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data-dom-id="ProfileCheckPaperUpdate-react-component-6366cfc4-019d-407c-8afd-78c9fa321dbe"></div> <div id="ProfileCheckPaperUpdate-react-component-6366cfc4-019d-407c-8afd-78c9fa321dbe"></div> <div class="DesignSystem"><div class="onsite-ping" id="onsite-ping"></div></div><div class="profile-user-info DesignSystem"><div class="social-profile-container"><div class="left-panel-container"><div class="user-info-component-wrapper"><div class="user-summary-cta-container"><div class="user-summary-container"><div class="social-profile-avatar-container"><img class="profile-avatar u-positionAbsolute" border="0" alt="" src="//a.academia-assets.com/images/s200_no_pic.png" /></div><div class="title-container"><h1 class="ds2-5-heading-sans-serif-sm">Luan-yin Chang</h1><div class="affiliations-container fake-truncate js-profile-affiliations"><div><a class="u-tcGrayDarker" href="https://taiwan.academia.edu/">National Taiwan University</a>, <a class="u-tcGrayDarker" 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class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Luan-yin Chang</h3></div><div class="js-work-strip profile--work_container" data-work-id="14115157"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115157/Multidrug_resistant_non_typhoid_Salmonella_infections_in_a_medical_center"><img alt="Research paper thumbnail of Multidrug-resistant non-typhoid Salmonella infections in a medical center" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115157/Multidrug_resistant_non_typhoid_Salmonella_infections_in_a_medical_center">Multidrug-resistant non-typhoid Salmonella infections in a medical center</a></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multidrug-resistant Salmonella has become of particular concern. This retrospective study assessed the clinical features of patients with multidrug-resistant Salmonella treated from January 1998 through June 2000. A total of 201 children and 33 adults with multidrug-resistant Salmonella infections treated during a 2.5-year period were included. Sixty-percent of these patients had used antibiotics before multidrug-resistant Salmonella infection developed. The incidence of extra-intestinal infections was higher in adults (51.4%) than in children (4.9%). Infection with an invasive serotype of Salmonella, such as Salmonella choleraesuis, and host factors appeared to be predisposing factors for bacteremia or extra-intestinal infections. None of the patients had mortality attributable to multidrug-resistant salmonellosis. The increasing rate of resistance to third-generation cephalosporins and fluo...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115157"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115157"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115157; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115157]").text(description); $(".js-view-count[data-work-id=14115157]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115157; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115157']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115157, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115157]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115157,"title":"Multidrug-resistant non-typhoid Salmonella infections in a medical center","translated_title":"","metadata":{"abstract":"Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multidrug-resistant Salmonella has become of particular concern. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115156"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115156/Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study"><img alt="Research paper thumbnail of Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115156/Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study">Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study</a></div><div class="wp-workCard_item"><span>Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to i...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to identify the risk factors for the acquisition of MRSA bacteremia in infants hospitalized in neonatal intensive care units (NICUs), 21 bloodstream isolates from 21 infants were genotyped and other 21 infants without MRSA bacteremia were matched for a case-control study. Two genotypes (A and C) were identified by pulsed-field gel electrophoresis and three genotypes (I, II and III) by infrequent-restriction-site polymerase chain reaction. Genotype C-III in 9 isolates and genotype A-I in 7 isolates were the two most common genotypes. The presence of skin infection at onset, prolonged prior duration of central venous catheter indwelling and prolonged hospital stay were significantly associated with MRSA bacteremia in these infants. With multiple logistic regression analysis, the presence of skin infection at onset was the only significant risk factor of MRSA bacteremia, with an odds ratio of 2...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115156"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115156"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115156; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115156]").text(description); $(".js-view-count[data-work-id=14115156]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115156; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115156']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115156, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115156]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115156,"title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study","translated_title":"","metadata":{"abstract":"To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to identify the risk factors for the acquisition of MRSA bacteremia in infants hospitalized in neonatal intensive care units (NICUs), 21 bloodstream isolates from 21 infants were genotyped and other 21 infants without MRSA bacteremia were matched for a case-control study. Two genotypes (A and C) were identified by pulsed-field gel electrophoresis and three genotypes (I, II and III) by infrequent-restriction-site polymerase chain reaction. Genotype C-III in 9 isolates and genotype A-I in 7 isolates were the two most common genotypes. The presence of skin infection at onset, prolonged prior duration of central venous catheter indwelling and prolonged hospital stay were significantly associated with MRSA bacteremia in these infants. With multiple logistic regression analysis, the presence of skin infection at onset was the only significant risk factor of MRSA bacteremia, with an odds ratio of 2...","publication_name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi"},"translated_abstract":"To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to identify the risk factors for the acquisition of MRSA bacteremia in infants hospitalized in neonatal intensive care units (NICUs), 21 bloodstream isolates from 21 infants were genotyped and other 21 infants without MRSA bacteremia were matched for a case-control study. Two genotypes (A and C) were identified by pulsed-field gel electrophoresis and three genotypes (I, II and III) by infrequent-restriction-site polymerase chain reaction. Genotype C-III in 9 isolates and genotype A-I in 7 isolates were the two most common genotypes. The presence of skin infection at onset, prolonged prior duration of central venous catheter indwelling and prolonged hospital stay were significantly associated with MRSA bacteremia in these infants. With multiple logistic regression analysis, the presence of skin infection at onset was the only significant risk factor of MRSA bacteremia, with an odds ratio of 2...","internal_url":"https://www.academia.edu/14115156/Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study","translated_internal_url":"","created_at":"2015-07-16T07:34:06.714-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292309,"work_id":14115156,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":607516,"email":"p***n@cgmh.org.tw","display_order":0,"name":"Tzou-yien Lin","title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study"},{"id":3292356,"work_id":14115156,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":530665,"email":"p***n@adm.cgmh.org.tw","display_order":4194304,"name":"Tzou-yien Lin","title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study"},{"id":3293143,"work_id":14115156,"tagging_user_id":33115704,"tagged_user_id":33121704,"co_author_invite_id":818623,"email":"s***i@gmail.com","display_order":6291456,"name":"Lin-hui Su","title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study"}],"downloadable_attachments":[],"slug":"Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115155"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115155/Large_Isoform_of_Mammalian_Relative_of_DnaJ_is_a_Major_Determinant_of_Human_Susceptibility_to_HIV_1_Infection"><img alt="Research paper thumbnail of Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection" class="work-thumbnail" src="https://attachments.academia-assets.com/44588948/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115155/Large_Isoform_of_Mammalian_Relative_of_DnaJ_is_a_Major_Determinant_of_Human_Susceptibility_to_HIV_1_Infection">Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection</a></div><div class="wp-workCard_item"><span>EBioMedicine</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of MRJ-L in monocyte-derived macrophages was significantly higher in HIV-infected individuals (n = 31) than their uninfected counterparts (n = 27) (p = 0.009). Fifty male homosexual subjects (20 of them are HIV-1 positive) were further recruited to examine the association between MRJ-L levels and occurrence of HIV infection. Bayesian multiple logistic regression revealed that playing a receptive role and increased levels of MRJ-L in macrophages were two risk factors for HIV-1 infection. A 1% rise in MRJ-L expression was associated with a 1.13 fold (95% CrI 1.06-1.29) increase in odds of contracting HIV-1 infection. Ex vivo experiments revealed that MRJ-L facilitated Vpr-dependent nuclear loca...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="339f34a4a157f8fba9a53f538ee9c50b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588948,"asset_id":14115155,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588948/download_file?st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115155"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115155"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115155; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115155]").text(description); $(".js-view-count[data-work-id=14115155]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115155; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115155']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115155, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "339f34a4a157f8fba9a53f538ee9c50b" } } $('.js-work-strip[data-work-id=14115155]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115155,"title":"Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection","translated_title":"","metadata":{"abstract":"Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of MRJ-L in monocyte-derived macrophages was significantly higher in HIV-infected individuals (n = 31) than their uninfected counterparts (n = 27) (p = 0.009). Fifty male homosexual subjects (20 of them are HIV-1 positive) were further recruited to examine the association between MRJ-L levels and occurrence of HIV infection. Bayesian multiple logistic regression revealed that playing a receptive role and increased levels of MRJ-L in macrophages were two risk factors for HIV-1 infection. A 1% rise in MRJ-L expression was associated with a 1.13 fold (95% CrI 1.06-1.29) increase in odds of contracting HIV-1 infection. Ex vivo experiments revealed that MRJ-L facilitated Vpr-dependent nuclear loca...","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"EBioMedicine"},"translated_abstract":"Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of MRJ-L in monocyte-derived macrophages was significantly higher in HIV-infected individuals (n = 31) than their uninfected counterparts (n = 27) (p = 0.009). Fifty male homosexual subjects (20 of them are HIV-1 positive) were further recruited to examine the association between MRJ-L levels and occurrence of HIV infection. Bayesian multiple logistic regression revealed that playing a receptive role and increased levels of MRJ-L in macrophages were two risk factors for HIV-1 infection. A 1% rise in MRJ-L expression was associated with a 1.13 fold (95% CrI 1.06-1.29) increase in odds of contracting HIV-1 infection. Ex vivo experiments revealed that MRJ-L facilitated Vpr-dependent nuclear loca...","internal_url":"https://www.academia.edu/14115155/Large_Isoform_of_Mammalian_Relative_of_DnaJ_is_a_Major_Determinant_of_Human_Susceptibility_to_HIV_1_Infection","translated_internal_url":"","created_at":"2015-07-16T07:34:06.608-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":44588948,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/44588948/thumbnails/1.jpg","file_name":"Large_Isoform_of_Mammalian_Relative_of_D20160410-28575-yj7nmh.pdf","download_url":"https://www.academia.edu/attachments/44588948/download_file?st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Large_Isoform_of_Mammalian_Relative_of_D.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/44588948/Large_Isoform_of_Mammalian_Relative_of_D20160410-28575-yj7nmh-libre.pdf?1460290158=\u0026response-content-disposition=attachment%3B+filename%3DLarge_Isoform_of_Mammalian_Relative_of_D.pdf\u0026Expires=1732462884\u0026Signature=IqCOESqZRVUCkpI1oSiRgKGBIir1liRRd~Bp1jwskwZJbbfjg6dPLClqd7qmHxPl5UN0B95CvuMfia~Dd0f8mucMPPFA9b1-FAhS-FICl9vrYXkOSgI1U68USFYtpOhyuU-Naly3~L4mrFjGOuftpC3G-Vha~vZacguujZWV3~BfWOXVjicVunHWc4UnXm13PRqLs3Rqs-L422wqEZB6jwsnx1y42Dwi9WAXLhMlGY2BHJNUmNqU5FiBIZXbV~ml1h24BqAZLT4eR5iJ56XmEodZ1CMNJxbDD~bY07kZ~BRCBTe5W55gw8CdDDbLa201WqlKtZ95qIBRuCUy-onDHA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Large_Isoform_of_Mammalian_Relative_of_DnaJ_is_a_Major_Determinant_of_Human_Susceptibility_to_HIV_1_Infection","translated_slug":"","page_count":7,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[{"id":44588948,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/44588948/thumbnails/1.jpg","file_name":"Large_Isoform_of_Mammalian_Relative_of_D20160410-28575-yj7nmh.pdf","download_url":"https://www.academia.edu/attachments/44588948/download_file?st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Large_Isoform_of_Mammalian_Relative_of_D.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/44588948/Large_Isoform_of_Mammalian_Relative_of_D20160410-28575-yj7nmh-libre.pdf?1460290158=\u0026response-content-disposition=attachment%3B+filename%3DLarge_Isoform_of_Mammalian_Relative_of_D.pdf\u0026Expires=1732462884\u0026Signature=IqCOESqZRVUCkpI1oSiRgKGBIir1liRRd~Bp1jwskwZJbbfjg6dPLClqd7qmHxPl5UN0B95CvuMfia~Dd0f8mucMPPFA9b1-FAhS-FICl9vrYXkOSgI1U68USFYtpOhyuU-Naly3~L4mrFjGOuftpC3G-Vha~vZacguujZWV3~BfWOXVjicVunHWc4UnXm13PRqLs3Rqs-L422wqEZB6jwsnx1y42Dwi9WAXLhMlGY2BHJNUmNqU5FiBIZXbV~ml1h24BqAZLT4eR5iJ56XmEodZ1CMNJxbDD~bY07kZ~BRCBTe5W55gw8CdDDbLa201WqlKtZ95qIBRuCUy-onDHA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115154"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115154/Molecular_diagnosis_and_clinical_presentations_of_enteroviral_infections_in_Taipei_during_the_2008_epidemic"><img alt="Research paper thumbnail of Molecular diagnosis and clinical presentations of enteroviral infections in Taipei during the 2008 epidemic" class="work-thumbnail" src="https://attachments.academia-assets.com/44588935/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115154/Molecular_diagnosis_and_clinical_presentations_of_enteroviral_infections_in_Taipei_during_the_2008_epidemic">Molecular diagnosis and clinical presentations of enteroviral infections in Taipei during the 2008 epidemic</a></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In 2008, an epidemic of enterovirus (EV) infection caused hand, foot, and mouth disease (HFMD) an...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In 2008, an epidemic of enterovirus (EV) infection caused hand, foot, and mouth disease (HFMD) and herpangina in children in Taiwan, and some of them died. To establish an early detection and effective management for children with EV71 infection, sensitive molecular diagnostic methods were applied from May to July 2008. We used virus isolation, EV71 real-time reverse-transcription polymerase chain reaction (RT-PCR), and viral protein 1 (VP1) RT-PCR followed by direct sequencing to detect EV71 and the other EVs in the infected outpatient or inpatient children. Clinical presentations of children infected with EV71 and other EVs were compared. From May 2008 to July 2008, 255 swabs were tested by both PCR diagnostic methods. Based on the viral isolation results, the sensitivities of EV71 real-time RT-PCR and VP1 RT-PCR followed by direct sequencing were 71% and 86%, respectively. Among the 221 children who were enrolled for clinical analysis, 73% (161 of 221) had herpangina, and 27% (60...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8a150fee6f40ce9ee4c98fd4b96ff4a5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588935,"asset_id":14115154,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588935/download_file?st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115154"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115154"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115154; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115154]").text(description); $(".js-view-count[data-work-id=14115154]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115154; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115154']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115154, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8a150fee6f40ce9ee4c98fd4b96ff4a5" } } $('.js-work-strip[data-work-id=14115154]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115154,"title":"Molecular diagnosis and clinical presentations of enteroviral infections in Taipei during the 2008 epidemic","translated_title":"","metadata":{"abstract":"In 2008, an epidemic of enterovirus (EV) infection caused hand, foot, and mouth disease (HFMD) and herpangina in children in Taiwan, and some of them died. 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src="https://attachments.academia-assets.com/38207868/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115153/HLA_A33_Is_Associated_With_Susceptibility_to_Enterovirus_71_Infection">HLA-A33 Is Associated With Susceptibility to Enterovirus 71 Infection</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">OBJECTIVE.Enterovirus 71 has caused large epidemics of disease, resulting in many fatalities and ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">OBJECTIVE.Enterovirus 71 has caused large epidemics of disease, resulting in many fatalities and severe sequelae, in Taiwan and some other countries. In this study, host genetic factors were investigated to link susceptibility to and clinical severity of enterovirus 71 infections. METHODS.We enrolled 219 enterovirus 71 case subjects and 97 control children. HLA typing was performed with sequence-specific primers, and polymorphisms</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bb22c7a379b25d09eb7e62247df0c5ac" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38207868,"asset_id":14115153,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38207868/download_file?st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115153"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115153"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115153; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115153]").text(description); $(".js-view-count[data-work-id=14115153]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115153; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115153']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115153, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bb22c7a379b25d09eb7e62247df0c5ac" } } $('.js-work-strip[data-work-id=14115153]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115153,"title":"HLA-A33 Is Associated With Susceptibility to Enterovirus 71 Infection","translated_title":"","metadata":{"abstract":"OBJECTIVE.Enterovirus 71 has caused large epidemics of disease, resulting in many fatalities and severe sequelae, in Taiwan and some other countries. 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manifestations and quantitative analysis of virus load in Taiwanese children with Epstein-Barr virus-associated infectious mononucleosis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115152/Clinical_manifestations_and_quantitative_analysis_of_virus_load_in_Taiwanese_children_with_Epstein_Barr_virus_associated_infectious_mononucleosis">Clinical manifestations and quantitative analysis of virus load in Taiwanese children with Epstein-Barr virus-associated infectious mononucleosis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background and Purpose: To delineate the clinical manifestations in different age groups and to d...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background and Purpose: To delineate the clinical manifestations in different age groups and to define the viral load in patients with Epstein-Barr virus-associated infectious mononucleosis (EBV-associated IM). Methods: We reviewed data on 69 children with EBV-associated IM from November 2001 to October 2005. Clinical features were evaluated among four age groups: &lt;3 years, 3 to 5 years, 6 to 9</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115152"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115152"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115152; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115152]").text(description); $(".js-view-count[data-work-id=14115152]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115152; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115152']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115152, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115152]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115152,"title":"Clinical manifestations and quantitative analysis of virus load in Taiwanese children with Epstein-Barr virus-associated infectious mononucleosis","translated_title":"","metadata":{"abstract":"Background and Purpose: To delineate the clinical manifestations in different age groups and to define the viral load in patients with Epstein-Barr virus-associated infectious mononucleosis (EBV-associated IM). 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class="js-work-more-abstract-truncated">+ CD25 + regulatory T cells and their phenotypic expression in peripheral blood of children with ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">+ CD25 + regulatory T cells and their phenotypic expression in peripheral blood of children with active and non-active juvenile idio- pathic arthritis (JIA) and healthy controls, to determine if their frequency or phenotypic expression is involved in the immunoregulation of this disease. Methods: From October 2004 to October 2005, 55 JIA patients and 55 age- and gender-matched healthy controls</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115151"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115151"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115151; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115151]").text(description); $(".js-view-count[data-work-id=14115151]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115151; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115151']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115151, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115151]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115151,"title":"Frequency and phenotypic analysis of CD4+CD25+ regulatory T cells in children with juvenile idiopathic arthritis","translated_title":"","metadata":{"abstract":"+ CD25 + regulatory T cells and their phenotypic expression in peripheral blood of children with active and non-active juvenile idio- pathic arthritis (JIA) and healthy controls, to determine if their frequency or phenotypic expression is involved in the immunoregulation of this disease. 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However, there is limited epidemiological data about RSV infection in Taiwan. This study aimed to investigate the clinical, epidemiological, virological, and economical aspects of RSV infections in Taiwan. Methods: We collected data of children with positive RSV respiratory specimens at the Laboratory</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115150"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115150"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115150; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115150]").text(description); $(".js-view-count[data-work-id=14115150]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115150; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115150']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115150, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115150]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115150,"title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden","translated_title":"","metadata":{"abstract":"Background and Purpose: Respiratory syncytial virus (RSV) is an important pathogen in children less than 2 years old. 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Methods: We collected data of children with positive RSV respiratory specimens at the Laboratory","internal_url":"https://www.academia.edu/14115150/Epidemiology_of_respiratory_syncytial_virus_infection_in_northern_Taiwan_2001_2005_seasonality_clinical_characteristics_and_disease_burden","translated_internal_url":"","created_at":"2015-07-16T07:34:05.902-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292431,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818511,"email":"c***u@ntu.edu.tw","display_order":0,"name":"Chun-yi Lu","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292543,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":43181325,"co_author_invite_id":818512,"email":"c***u@ntuh.gov.tw","display_order":4194304,"name":"Chun-yi Lu","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292681,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818517,"email":"p***g@ntumc.org","display_order":6291456,"name":"Ping-ing Lee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292711,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":297031361,"co_author_invite_id":818518,"email":"p***g@ntu.edu.tw","display_order":7340032,"name":"Ping-ing Lee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292882,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818534,"email":"s***7@ms38.hinet.net","display_order":7864320,"name":"Pei-lan Shao","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292955,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818544,"email":"y***u@ntu.edu.tw","display_order":8126464,"name":"Chin-yun Lee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3293001,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818555,"email":"p***8@ntnu.edu.tw","display_order":8257536,"name":"Ping- Inglee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"}],"downloadable_attachments":[],"slug":"Epidemiology_of_respiratory_syncytial_virus_infection_in_northern_Taiwan_2001_2005_seasonality_clinical_characteristics_and_disease_burden","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[{"id":57433,"name":"Seasonality","url":"https://www.academia.edu/Documents/in/Seasonality"},{"id":208136,"name":"Respiratory Syncytial Virus","url":"https://www.academia.edu/Documents/in/Respiratory_Syncytial_Virus"},{"id":263029,"name":"Intensive Care Unit","url":"https://www.academia.edu/Documents/in/Intensive_Care_Unit"},{"id":883945,"name":"Chronic lung disease","url":"https://www.academia.edu/Documents/in/Chronic_lung_disease"},{"id":1505497,"name":"Endotracheal intubation","url":"https://www.academia.edu/Documents/in/Endotracheal_intubation"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115149"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115149/Stenotrophomonas_maltophilia_bacteremia_in_pediatric_patients_a_10_year_analysis"><img alt="Research paper thumbnail of Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115149/Stenotrophomonas_maltophilia_bacteremia_in_pediatric_patients_a_10_year_analysis">Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Results: In total, 32 episodes (31 patients) of S. maltophilia bacteremia were reviewed. The aver...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Results: In total, 32 episodes (31 patients) of S. maltophilia bacteremia were reviewed. The average rate of nosocomial bloodstream infection was 8.3 episodes per 100,000 patient-days, and an average of 6.4% of them were caused by S. maltophilia. Malignancy was the most common underlying disease (32%). Six episodes of S. maltophilia bacteremia had soft tissue involvement, and only 1 of</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115149"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115149"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115149; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115149]").text(description); $(".js-view-count[data-work-id=14115149]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115149; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115149']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115149, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115149]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115149,"title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis","translated_title":"","metadata":{"abstract":"Results: In total, 32 episodes (31 patients) of S. maltophilia bacteremia were reviewed. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115148"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115148/Clinical_characteristics_of_children_with_influenza_A_virus_infection_requiring_hospitalization"><img alt="Research paper thumbnail of Clinical characteristics of children with influenza A virus infection requiring hospitalization" class="work-thumbnail" src="https://attachments.academia-assets.com/44588970/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115148/Clinical_characteristics_of_children_with_influenza_A_virus_infection_requiring_hospitalization">Clinical characteristics of children with influenza A virus infection requiring hospitalization</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">From September 1997 to March 2002, a total of 84 children were admitted to Chang Gung Children&#3...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">From September 1997 to March 2002, a total of 84 children were admitted to Chang Gung Children&#39;s Hospital due to influenza A virus infection. Influenza A virus infection was documented in 61 cases by viral isolation from throat and in 23 cases by serologic studies. The mean age of patients was 43.8 months, ranging from 20 days to 16 years.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b9834f70305276de5734ed4550b396f9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588970,"asset_id":14115148,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588970/download_file?st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115148"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115148"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115148; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115148]").text(description); $(".js-view-count[data-work-id=14115148]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115148; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115148']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115148, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b9834f70305276de5734ed4550b396f9" } } $('.js-work-strip[data-work-id=14115148]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115148,"title":"Clinical characteristics of children with influenza A virus infection requiring hospitalization","translated_title":"","metadata":{"abstract":"From September 1997 to March 2002, a total of 84 children were admitted to Chang Gung Children\u0026#39;s Hospital due to influenza A virus infection. 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href="https://www.academia.edu/14115146/Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease"><img alt="Research paper thumbnail of Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115146/Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease">Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JoukouWang">Jou-kou Wang</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ChangChinhao">Chin-hao Chang</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/ChunanChen">Chun-an Chen</a></span></div><div class="wp-workCard_item"><span>Journal of the Formosan Medical Association = Taiwan yi zhi</span><span>, Jan 21, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Kawasaki disease (KD) is the most common pediatric vasculitis. The study aimed to identify the ri...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Kawasaki disease (KD) is the most common pediatric vasculitis. The study aimed to identify the risk factors of intravenous immunoglobulin (IVIG) unresponsiveness from the initial clinical parameters of the Taiwanese KD patients. We enrolled 248 KD (development dataset: 181, validation: 67) patients who received IVIG within 10 days after fever onset. IVIG unresponsiveness was defined by persistent fever beyond 24 hours after IVIG or recrudescent fever with KD symptoms. From the development dataset (181 patients), IVIG unresponsiveness was noted in 22 patients (12.1%). The preIVIG levels of albumin, percentage of neutrophils, and positive lymphadenopathy were identified with highest risk for IVIG unresponsiveness. These three variables were used to construct a three-variable logistic regression model, which yielded an area under the receiver-operating-characteristics curve of 0.87. These three variables were further used to generate a composite scoring model (Formosa score) which yiel...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115146"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115146"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115146; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115146]").text(description); $(".js-view-count[data-work-id=14115146]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115146; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115146']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115146, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115146]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115146,"title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease","translated_title":"","metadata":{"abstract":"Kawasaki disease (KD) is the most common pediatric vasculitis. 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These three variables were further used to generate a composite scoring model (Formosa score) which yiel...","publication_date":{"day":21,"month":1,"year":2015,"errors":{}},"publication_name":"Journal of the Formosan Medical Association = Taiwan yi zhi"},"translated_abstract":"Kawasaki disease (KD) is the most common pediatric vasculitis. The study aimed to identify the risk factors of intravenous immunoglobulin (IVIG) unresponsiveness from the initial clinical parameters of the Taiwanese KD patients. We enrolled 248 KD (development dataset: 181, validation: 67) patients who received IVIG within 10 days after fever onset. IVIG unresponsiveness was defined by persistent fever beyond 24 hours after IVIG or recrudescent fever with KD symptoms. From the development dataset (181 patients), IVIG unresponsiveness was noted in 22 patients (12.1%). The preIVIG levels of albumin, percentage of neutrophils, and positive lymphadenopathy were identified with highest risk for IVIG unresponsiveness. These three variables were used to construct a three-variable logistic regression model, which yielded an area under the receiver-operating-characteristics curve of 0.87. These three variables were further used to generate a composite scoring model (Formosa score) which yiel...","internal_url":"https://www.academia.edu/14115146/Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease","translated_internal_url":"","created_at":"2015-07-16T07:34:05.235-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292717,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":721755,"email":"w***h@ntu.edu.tw","display_order":0,"name":"Mei-hwan Wu","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":3292754,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":36647501,"co_author_invite_id":818520,"email":"j***w@ntuh.gov.tw","display_order":4194304,"name":"Jou-kou Wang","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":3292757,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":37027739,"co_author_invite_id":818521,"email":"c***o@ntuh.gov.tw","display_order":6291456,"name":"Chin-hao Chang","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":3293085,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818594,"email":"j***y@taigen.com","display_order":7340032,"name":"M. Lin","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":7814003,"work_id":14115146,"tagging_user_id":36647501,"tagged_user_id":36595650,"co_author_invite_id":null,"email":"c***a@ntu.edu.tw","affiliation":"National Taiwan University","display_order":7864320,"name":"Chun-an Chen","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":7814004,"work_id":14115146,"tagging_user_id":36647501,"tagged_user_id":null,"co_author_invite_id":1744818,"email":"h***u@gmail.com","display_order":8126464,"name":"Hsin-min Liu","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"}],"downloadable_attachments":[],"slug":"Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115145"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115145/Effect_of_intravenous_immunoglobulin_for_neonates_with_severe_enteroviral_infections_with_emphasis_on_the_timing_of_administration"><img alt="Research paper thumbnail of Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration" class="work-thumbnail" src="https://attachments.academia-assets.com/44588958/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115145/Effect_of_intravenous_immunoglobulin_for_neonates_with_severe_enteroviral_infections_with_emphasis_on_the_timing_of_administration">Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration</a></div><div class="wp-workCard_item"><span>Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infecti...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infections are still controversial. To evaluate whether timing of IVIG administration might affect clinical outcomes of neonates with severe enteroviral infections. We retrospectively analyzed 67 neonates with culture-confirmed severe enteroviral infection, defined as hepatitis with coagulopathy and thrombocytopenia. Clinical features, outcomes and the usage of IVIG therapy were collected and analyzed. IVIG administered within 3 days of illness onset was classified as early IVIG therapy. Of the 67 cases, 38 (57%) were male, 27 (40%) were premature, 57 (85%) had disease onset within 7 days of life and all but 2 cases were caused by coxsackievirus B group. Ten infants (15%) had clinically evident myocarditis. 41 infants (61%) received IVIG therapy and 29 were early IVIG therapy. Fifteen infants (22%) eventually died, without IVIG therapy for 7 infants. The deceased had a significantly higher peak...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bb17763ed6ee88b4531ffb28ca4c07f7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588958,"asset_id":14115145,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588958/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115145"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115145"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115145; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115145]").text(description); $(".js-view-count[data-work-id=14115145]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115145; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115145']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115145, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bb17763ed6ee88b4531ffb28ca4c07f7" } } $('.js-work-strip[data-work-id=14115145]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115145,"title":"Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration","translated_title":"","metadata":{"abstract":"The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infections are still controversial. To evaluate whether timing of IVIG administration might affect clinical outcomes of neonates with severe enteroviral infections. We retrospectively analyzed 67 neonates with culture-confirmed severe enteroviral infection, defined as hepatitis with coagulopathy and thrombocytopenia. Clinical features, outcomes and the usage of IVIG therapy were collected and analyzed. IVIG administered within 3 days of illness onset was classified as early IVIG therapy. Of the 67 cases, 38 (57%) were male, 27 (40%) were premature, 57 (85%) had disease onset within 7 days of life and all but 2 cases were caused by coxsackievirus B group. Ten infants (15%) had clinically evident myocarditis. 41 infants (61%) received IVIG therapy and 29 were early IVIG therapy. Fifteen infants (22%) eventually died, without IVIG therapy for 7 infants. The deceased had a significantly higher peak...","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology"},"translated_abstract":"The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infections are still controversial. To evaluate whether timing of IVIG administration might affect clinical outcomes of neonates with severe enteroviral infections. We retrospectively analyzed 67 neonates with culture-confirmed severe enteroviral infection, defined as hepatitis with coagulopathy and thrombocytopenia. Clinical features, outcomes and the usage of IVIG therapy were collected and analyzed. IVIG administered within 3 days of illness onset was classified as early IVIG therapy. Of the 67 cases, 38 (57%) were male, 27 (40%) were premature, 57 (85%) had disease onset within 7 days of life and all but 2 cases were caused by coxsackievirus B group. Ten infants (15%) had clinically evident myocarditis. 41 infants (61%) received IVIG therapy and 29 were early IVIG therapy. Fifteen infants (22%) eventually died, without IVIG therapy for 7 infants. The deceased had a significantly higher peak...","internal_url":"https://www.academia.edu/14115145/Effect_of_intravenous_immunoglobulin_for_neonates_with_severe_enteroviral_infections_with_emphasis_on_the_timing_of_administration","translated_internal_url":"","created_at":"2015-07-16T07:34:05.083-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292300,"work_id":14115145,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":607516,"email":"p***n@cgmh.org.tw","display_order":0,"name":"Tzou-yien Lin","title":"Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration"},{"id":3292347,"work_id":14115145,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":530665,"email":"p***n@adm.cgmh.org.tw","display_order":4194304,"name":"Tzou-yien Lin","title":"Effect of 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thumbnail of Central venous catheter-associated bloodstream infections in pediatric hematology-oncology patients and effectiveness of antimicrobial lock therapy" class="work-thumbnail" src="https://attachments.academia-assets.com/44588983/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115144/Central_venous_catheter_associated_bloodstream_infections_in_pediatric_hematology_oncology_patients_and_effectiveness_of_antimicrobial_lock_therapy">Central venous catheter-associated bloodstream infections in pediatric hematology-oncology patients and effectiveness of antimicrobial lock therapy</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span><span>, Jan 10, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-on...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-oncology patients. This study aimed to analyze the prevalence of CLABSI and the effectiveness of antimicrobial lock therapy (ALT) in pediatric patients. BSIs of all pediatric hematology-oncology patients admitted to a children&#39;s hospital between January 2009 and December 2013 were reviewed. The United States National Healthcare Safety Network and Infectious Diseases Society of America guidelines were used to define CLABSI and catheter-related BSI (CRBSI). The incidence, laboratory and microbiology characteristics, poor outcome, and effectiveness of ALT were analyzed. There were 246 cases of CLABSI in 146 patients (mean age, 10.0 years), including 66 (26.8%) cases of CRBSI. The incidence of CLABSI was 4.49/1000 catheter-days, and the infection was responsible for 32.9% of the complications these patients developed and 9.3% of contributable mortality. Patients with acute myeloid leukemia...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="393a7d7419d5332406a60feda6d83fc6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588983,"asset_id":14115144,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588983/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115144"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115144"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115144; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115144]").text(description); $(".js-view-count[data-work-id=14115144]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115144; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115144']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115144, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "393a7d7419d5332406a60feda6d83fc6" } } $('.js-work-strip[data-work-id=14115144]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115144,"title":"Central venous catheter-associated bloodstream infections in pediatric hematology-oncology patients and effectiveness of antimicrobial lock therapy","translated_title":"","metadata":{"abstract":"Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-oncology patients. This study aimed to analyze the prevalence of CLABSI and the effectiveness of antimicrobial lock therapy (ALT) in pediatric patients. BSIs of all pediatric hematology-oncology patients admitted to a children\u0026#39;s hospital between January 2009 and December 2013 were reviewed. The United States National Healthcare Safety Network and Infectious Diseases Society of America guidelines were used to define CLABSI and catheter-related BSI (CRBSI). The incidence, laboratory and microbiology characteristics, poor outcome, and effectiveness of ALT were analyzed. There were 246 cases of CLABSI in 146 patients (mean age, 10.0 years), including 66 (26.8%) cases of CRBSI. The incidence of CLABSI was 4.49/1000 catheter-days, and the infection was responsible for 32.9% of the complications these patients developed and 9.3% of contributable mortality. Patients with acute myeloid leukemia...","publication_date":{"day":10,"month":1,"year":2014,"errors":{}},"publication_name":"Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi"},"translated_abstract":"Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-oncology patients. This study aimed to analyze the prevalence of CLABSI and the effectiveness of antimicrobial lock therapy (ALT) in pediatric patients. BSIs of all pediatric hematology-oncology patients admitted to a children\u0026#39;s hospital between January 2009 and December 2013 were reviewed. The United States National Healthcare Safety Network and Infectious Diseases Society of America guidelines were used to define CLABSI and catheter-related BSI (CRBSI). The incidence, laboratory and microbiology characteristics, poor outcome, and effectiveness of ALT were analyzed. 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/></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115143/Campylobacter_enteritis_in_children_in_northern_Taiwan_a_7_year_experience">Campylobacter enteritis in children in northern Taiwan--a 7-year experience</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/YuChiaHsieh">Yu Chia Hsieh</a></span></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Campylobacter infection is recognized as a major cause of acute enteritis in humans. The clinical...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Campylobacter infection is recognized as a major cause of acute enteritis in humans. The clinical characteristics may vary in different countries. This study investigated the clinical manifestations of pediatric Campylobacter enteritis in a medical center in northern Taiwan. This was a retrospective review of Campylobacter enteritis infections at National Taiwan University Hospital, Taipei, Taiwan, from January 2000 to December 2006. All children who tested positive for Campylobacter, isolated from stool samples, were included in the study. Data collected and evaluated included the species of Campylobacter, age, gender, underlying disease, travel history, clinical manifestations and laboratory data. A total of 104 patients had enteric campylobacteriosis. Campylobacter coli was grown from 24 patients (23.1%), while Campylobacter jejuni was found in 80 patients (76.9%). More than half of the infections (60.6%) occurred in children less than 5 years old. The male-to-female ratio was 2....</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115143"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115143"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115143; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115143]").text(description); $(".js-view-count[data-work-id=14115143]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115143; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115143']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115143, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115143]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115143,"title":"Campylobacter enteritis in children in northern Taiwan--a 7-year experience","translated_title":"","metadata":{"abstract":"Campylobacter infection is recognized as a major cause of acute enteritis in humans. The clinical characteristics may vary in different countries. This study investigated the clinical manifestations of pediatric Campylobacter enteritis in a medical center in northern Taiwan. This was a retrospective review of Campylobacter enteritis infections at National Taiwan University Hospital, Taipei, Taiwan, from January 2000 to December 2006. All children who tested positive for Campylobacter, isolated from stool samples, were included in the study. Data collected and evaluated included the species of Campylobacter, age, gender, underlying disease, travel history, clinical manifestations and laboratory data. A total of 104 patients had enteric campylobacteriosis. Campylobacter coli was grown from 24 patients (23.1%), while Campylobacter jejuni was found in 80 patients (76.9%). More than half of the infections (60.6%) occurred in children less than 5 years old. The male-to-female ratio was 2....","publication_date":{"day":null,"month":null,"year":2008,"errors":{}},"publication_name":"Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi"},"translated_abstract":"Campylobacter infection is recognized as a major cause of acute enteritis in humans. The clinical characteristics may vary in different countries. This study investigated the clinical manifestations of pediatric Campylobacter enteritis in a medical center in northern Taiwan. This was a retrospective review of Campylobacter enteritis infections at National Taiwan University Hospital, Taipei, Taiwan, from January 2000 to December 2006. All children who tested positive for Campylobacter, isolated from stool samples, were included in the study. Data collected and evaluated included the species of Campylobacter, age, gender, underlying disease, travel history, clinical manifestations and laboratory data. A total of 104 patients had enteric campylobacteriosis. Campylobacter coli was grown from 24 patients (23.1%), while Campylobacter jejuni was found in 80 patients (76.9%). More than half of the infections (60.6%) occurred in children less than 5 years old. 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Study","url":"https://www.academia.edu/Documents/in/Retrospective_Study"},{"id":1180715,"name":"Abdominal Pain","url":"https://www.academia.edu/Documents/in/Abdominal_Pain"},{"id":1249381,"name":"Campylobacter jejuni","url":"https://www.academia.edu/Documents/in/Campylobacter_jejuni"},{"id":2036233,"name":"Campylobacter coli","url":"https://www.academia.edu/Documents/in/Campylobacter_coli"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115142"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115142/Lack_of_association_between_infection_with_a_novel_human_coronavirus_HCoV_HCoV_NH_and_Kawasaki_disease_in_Taiwan"><img alt="Research paper thumbnail of Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115142/Lack_of_association_between_infection_with_a_novel_human_coronavirus_HCoV_HCoV_NH_and_Kawasaki_disease_in_Taiwan">Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan</a></div><div class="wp-workCard_item"><span>The Journal of infectious diseases</span><span>, Jan 15, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We investigated whether infection with a novel human coronavirus (HCoV), called &quot;New Haven c...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We investigated whether infection with a novel human coronavirus (HCoV), called &quot;New Haven coronavirus&quot; (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115142"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115142"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115142; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115142]").text(description); $(".js-view-count[data-work-id=14115142]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115142; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115142']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115142, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115142]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115142,"title":"Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan","translated_title":"","metadata":{"abstract":"We investigated whether infection with a novel human coronavirus (HCoV), called \u0026quot;New Haven coronavirus\u0026quot; (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.","publication_date":{"day":15,"month":1,"year":2006,"errors":{}},"publication_name":"The Journal of infectious diseases"},"translated_abstract":"We investigated whether infection with a novel human coronavirus (HCoV), called \u0026quot;New Haven coronavirus\u0026quot; (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.","internal_url":"https://www.academia.edu/14115142/Lack_of_association_between_infection_with_a_novel_human_coronavirus_HCoV_HCoV_NH_and_Kawasaki_disease_in_Taiwan","translated_internal_url":"","created_at":"2015-07-16T07:34:04.754-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292719,"work_id":14115142,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":721755,"email":"w***h@ntu.edu.tw","display_order":0,"name":"Mei-hwan Wu","title":"Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan"},{"id":3292748,"work_id":14115142,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":695744,"email":"p***n@ntu.edu.tw","display_order":4194304,"name":"Pei-jer Chen","title":"Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan"}],"downloadable_attachments":[],"slug":"Lack_of_association_between_infection_with_a_novel_human_coronavirus_HCoV_HCoV_NH_and_Kawasaki_disease_in_Taiwan","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":94451,"name":"Taiwan","url":"https://www.academia.edu/Documents/in/Taiwan"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":210665,"name":"Infectious","url":"https://www.academia.edu/Documents/in/Infectious"},{"id":837636,"name":"SERUM","url":"https://www.academia.edu/Documents/in/SERUM"},{"id":1305891,"name":"Coronavirus","url":"https://www.academia.edu/Documents/in/Coronavirus"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115141"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115141/Childhood_severe_acute_respiratory_syndrome_in_Taiwan_and_how_to_differentiate_it_from_childhood_influenza_infection"><img alt="Research paper thumbnail of Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115141/Childhood_severe_acute_respiratory_syndrome_in_Taiwan_and_how_to_differentiate_it_from_childhood_influenza_infection">Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection</a></div><div class="wp-workCard_item"><span>Archives of pediatrics & adolescent medicine</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed sev...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed severe acute respiratory syndrome (SARS) vs those of children with influenza to differentiate the 2 diseases. Patients 20 years or younger with clinical, epidemiological, and laboratory evidence of SARS from March to July 2003 vs children with virus culture-confirmed influenza in a 1:1 age- and sex-matched control group. Rates of symptoms, abnormal laboratory data, and outcomes of recovery, sequelae, or death. The 15 SARS patients (9 girls and 6 boys) had a median age of 17 years (age range, 4-20 years). Nine patients (60%) were infected through household contact, 4 (27%) nosocomially, 1 (7%) through contact with a neighbor, and 1 (7%) after returning from Hong Kong. All 15 patients had fever, 3 (20%) had chills, and 11 (73%) had cough. Only 1 patient (7%) had sputum production; 1 (7%) had rhinorrhea. At presentation, 5 patients (33%) had leukopenia, 6 (40%) had lymphopenia, and 5 (33%) had...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115141"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115141"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115141; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115141]").text(description); $(".js-view-count[data-work-id=14115141]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115141; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115141']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115141, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115141]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115141,"title":"Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection","translated_title":"","metadata":{"abstract":"To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed severe acute respiratory syndrome (SARS) vs those of children with influenza to differentiate the 2 diseases. Patients 20 years or younger with clinical, epidemiological, and laboratory evidence of SARS from March to July 2003 vs children with virus culture-confirmed influenza in a 1:1 age- and sex-matched control group. Rates of symptoms, abnormal laboratory data, and outcomes of recovery, sequelae, or death. The 15 SARS patients (9 girls and 6 boys) had a median age of 17 years (age range, 4-20 years). Nine patients (60%) were infected through household contact, 4 (27%) nosocomially, 1 (7%) through contact with a neighbor, and 1 (7%) after returning from Hong Kong. All 15 patients had fever, 3 (20%) had chills, and 11 (73%) had cough. Only 1 patient (7%) had sputum production; 1 (7%) had rhinorrhea. At presentation, 5 patients (33%) had leukopenia, 6 (40%) had lymphopenia, and 5 (33%) had...","publication_date":{"day":null,"month":null,"year":2004,"errors":{}},"publication_name":"Archives of pediatrics \u0026 adolescent medicine"},"translated_abstract":"To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed severe acute respiratory syndrome (SARS) vs those of children with influenza to differentiate the 2 diseases. Patients 20 years or younger with clinical, epidemiological, and laboratory evidence of SARS from March to July 2003 vs children with virus culture-confirmed influenza in a 1:1 age- and sex-matched control group. Rates of symptoms, abnormal laboratory data, and outcomes of recovery, sequelae, or death. The 15 SARS patients (9 girls and 6 boys) had a median age of 17 years (age range, 4-20 years). Nine patients (60%) were infected through household contact, 4 (27%) nosocomially, 1 (7%) through contact with a neighbor, and 1 (7%) after returning from Hong Kong. All 15 patients had fever, 3 (20%) had chills, and 11 (73%) had cough. Only 1 patient (7%) had sputum production; 1 (7%) had rhinorrhea. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115140"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115140/Transmission_and_clinical_features_of_enterovirus_71_infections_in_household_contacts_in_Taiwan"><img alt="Research paper thumbnail of Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan" class="work-thumbnail" src="https://attachments.academia-assets.com/44588956/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115140/Transmission_and_clinical_features_of_enterovirus_71_infections_in_household_contacts_in_Taiwan">Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan</a></div><div class="wp-workCard_item"><span>JAMA</span><span>, Jan 14, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Although enterovirus 71 has caused epidemics associated with significant morbidity and mortality,...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Although enterovirus 71 has caused epidemics associated with significant morbidity and mortality, its transmission has not been thoroughly investigated. To investigate enterovirus 71 transmission and determine clinical outcomes within households. Prospective family cohort study to investigate patients at a children&#39;s hospital in Taiwan and family members of these patients who had signs and symptoms suggestive of enterovirus 71 between February 2001 and August 2002. Patients and household members underwent clinical evaluations, virological studies, questionnaire-based interviews, and were followed up for 6 months. Enterovirus 71 infection, defined as a positive viral culture from a throat or rectal swab, or the presence of IgM or a 4-fold increase in neutralizing antibody in serum; and clinical syndromes, defined as asymptomatic; uncomplicated symptomatic; and complicated; with unfavorable outcomes of sequelae or death. Ninety-four families (433 family members) had at least 1 fam...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b49a0f6e61039531b50a1e5f54eb15fa" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588956,"asset_id":14115140,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588956/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115140"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115140"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115140; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115140]").text(description); $(".js-view-count[data-work-id=14115140]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115140; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115140']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115140, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b49a0f6e61039531b50a1e5f54eb15fa" } } $('.js-work-strip[data-work-id=14115140]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115140,"title":"Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan","translated_title":"","metadata":{"abstract":"Although enterovirus 71 has caused epidemics associated with significant morbidity and mortality, its transmission has not been thoroughly investigated. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115139"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115139/Influenza_in_Taiwan_seasonality_and_vaccine_strain_match"><img alt="Research paper thumbnail of Influenza in Taiwan: seasonality and vaccine strain match" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115139/Influenza_in_Taiwan_seasonality_and_vaccine_strain_match">Influenza in Taiwan: seasonality and vaccine strain match</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/YuChiaHsieh">Yu Chia Hsieh</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This article explores seasonality, epidemiology and dominant epidemic strains of influenza in Tai...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This article explores seasonality, epidemiology and dominant epidemic strains of influenza in Taiwan. Surveillance in Taiwan demonstrates that influenza is a disease which occurs throughout the year but has peak activity in winter. Due to the high mutability of influenza virus, effective vaccination is the best strategy for protection. Although the World Health Organization-recommended vaccine compositions usually matched with around</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115139"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115139"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115139; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115139]").text(description); $(".js-view-count[data-work-id=14115139]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115139; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115139']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115139, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115139]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115139,"title":"Influenza in Taiwan: seasonality and vaccine strain match","translated_title":"","metadata":{"abstract":"This article explores seasonality, epidemiology and dominant epidemic strains of influenza in Taiwan. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115138"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115138/Status_of_cellular_rather_than_humoral_immunity_is_correlated_with_clinical_outcome_of_enterovirus_71"><img alt="Research paper thumbnail of Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71" class="work-thumbnail" src="https://attachments.academia-assets.com/44588957/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115138/Status_of_cellular_rather_than_humoral_immunity_is_correlated_with_clinical_outcome_of_enterovirus_71">Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span>Pediatric research</span><span>, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We valuated specific cellular and humoral immune response of cases of enterovirus 71 (EV71) infec...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We valuated specific cellular and humoral immune response of cases of enterovirus 71 (EV71) infection and correlated immune response with clinical outcome. After obtaining informed consent, we enrolled 30 EV71 cases including 7 cases with brainstem encephalitis plus pulmonary edema, 12 cases of CNS (CNS) involvement and 11 uncomplicated cases. We measured antibodies specific to EV71, lymphocyte proliferation response and EV71-stimulated cellular response of Th1/Th2 cytokines and chemokines. The 7 EV71 cases involving brainstem encephalitis plus pulmonary edema had a significantly lower phytohemagglutinin stimulation index than other cases (p = 0.04). After EV71 stimulation of peripheral mononuclear cells, there was a significant increase in cellular Th1 cytokine (gamma-interferon) and proinflammatroy cytokines. However, cases with pulmonary edema had significantly lower cellular gamma-interferon (p = 0.04), lower cellular IL-1beta (p = 0.04), lower cellular IL-6 (p = 0.04), lower ce...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e5a42fe39aec1035c9bbc9fb121be2dd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588957,"asset_id":14115138,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588957/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115138"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115138"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115138; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115138]").text(description); $(".js-view-count[data-work-id=14115138]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115138; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115138']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115138, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "e5a42fe39aec1035c9bbc9fb121be2dd" } } $('.js-work-strip[data-work-id=14115138]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115138,"title":"Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71","translated_title":"","metadata":{"abstract":"We valuated specific cellular and humoral immune response of cases of enterovirus 71 (EV71) infection and correlated immune response with clinical outcome. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="3231942" id="papers"><div class="js-work-strip profile--work_container" data-work-id="14115157"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115157/Multidrug_resistant_non_typhoid_Salmonella_infections_in_a_medical_center"><img alt="Research paper thumbnail of Multidrug-resistant non-typhoid Salmonella infections in a medical center" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115157/Multidrug_resistant_non_typhoid_Salmonella_infections_in_a_medical_center">Multidrug-resistant non-typhoid Salmonella infections in a medical center</a></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multidrug-resistant Salmonella has become of particular concern. This retrospective study assessed the clinical features of patients with multidrug-resistant Salmonella treated from January 1998 through June 2000. A total of 201 children and 33 adults with multidrug-resistant Salmonella infections treated during a 2.5-year period were included. Sixty-percent of these patients had used antibiotics before multidrug-resistant Salmonella infection developed. The incidence of extra-intestinal infections was higher in adults (51.4%) than in children (4.9%). Infection with an invasive serotype of Salmonella, such as Salmonella choleraesuis, and host factors appeared to be predisposing factors for bacteremia or extra-intestinal infections. None of the patients had mortality attributable to multidrug-resistant salmonellosis. The increasing rate of resistance to third-generation cephalosporins and fluo...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115157"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115157"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115157; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115157]").text(description); $(".js-view-count[data-work-id=14115157]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115157; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115157']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115157, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115157]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115157,"title":"Multidrug-resistant non-typhoid Salmonella infections in a medical center","translated_title":"","metadata":{"abstract":"Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multidrug-resistant Salmonella has become of particular concern. 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The increasing rate of resistance to third-generation cephalosporins and fluo...","publication_name":"Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi"},"translated_abstract":"Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multidrug-resistant Salmonella has become of particular concern. This retrospective study assessed the clinical features of patients with multidrug-resistant Salmonella treated from January 1998 through June 2000. A total of 201 children and 33 adults with multidrug-resistant Salmonella infections treated during a 2.5-year period were included. Sixty-percent of these patients had used antibiotics before multidrug-resistant Salmonella infection developed. The incidence of extra-intestinal infections was higher in adults (51.4%) than in children (4.9%). Infection with an invasive serotype of Salmonella, such as Salmonella choleraesuis, and host factors appeared to be predisposing factors for bacteremia or extra-intestinal infections. None of the patients had mortality attributable to multidrug-resistant salmonellosis. The increasing rate of resistance to third-generation cephalosporins and fluo...","internal_url":"https://www.academia.edu/14115157/Multidrug_resistant_non_typhoid_Salmonella_infections_in_a_medical_center","translated_internal_url":"","created_at":"2015-07-16T07:34:06.827-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3293144,"work_id":14115157,"tagging_user_id":33115704,"tagged_user_id":33121704,"co_author_invite_id":818623,"email":"s***i@gmail.com","display_order":0,"name":"Lin-hui Su","title":"Multidrug-resistant non-typhoid Salmonella infections in a medical center"},{"id":3293157,"work_id":14115157,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818627,"email":"h***u@essex.ac.uk","display_order":4194304,"name":"Cheng Chiu","title":"Multidrug-resistant non-typhoid Salmonella infections in a medical center"}],"downloadable_attachments":[],"slug":"Multidrug_resistant_non_typhoid_Salmonella_infections_in_a_medical_center","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[{"id":310,"name":"Demography","url":"https://www.academia.edu/Documents/in/Demography"},{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology"},{"id":6947,"name":"Medical Microbiology","url":"https://www.academia.edu/Documents/in/Medical_Microbiology"},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome"},{"id":24089,"name":"Causality","url":"https://www.academia.edu/Documents/in/Causality"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":96213,"name":"Hospitalization","url":"https://www.academia.edu/Documents/in/Hospitalization"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant"},{"id":257897,"name":"Salmonella","url":"https://www.academia.edu/Documents/in/Salmonella"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":291136,"name":"Intestines","url":"https://www.academia.edu/Documents/in/Intestines"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":469102,"name":"Feces","url":"https://www.academia.edu/Documents/in/Feces"},{"id":525310,"name":"Bacteremia","url":"https://www.academia.edu/Documents/in/Bacteremia"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115156"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115156/Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study"><img alt="Research paper thumbnail of Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115156/Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study">Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study</a></div><div class="wp-workCard_item"><span>Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to i...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to identify the risk factors for the acquisition of MRSA bacteremia in infants hospitalized in neonatal intensive care units (NICUs), 21 bloodstream isolates from 21 infants were genotyped and other 21 infants without MRSA bacteremia were matched for a case-control study. Two genotypes (A and C) were identified by pulsed-field gel electrophoresis and three genotypes (I, II and III) by infrequent-restriction-site polymerase chain reaction. Genotype C-III in 9 isolates and genotype A-I in 7 isolates were the two most common genotypes. The presence of skin infection at onset, prolonged prior duration of central venous catheter indwelling and prolonged hospital stay were significantly associated with MRSA bacteremia in these infants. With multiple logistic regression analysis, the presence of skin infection at onset was the only significant risk factor of MRSA bacteremia, with an odds ratio of 2...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115156"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115156"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115156; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115156]").text(description); $(".js-view-count[data-work-id=14115156]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115156; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115156']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115156, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115156]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115156,"title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study","translated_title":"","metadata":{"abstract":"To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to identify the risk factors for the acquisition of MRSA bacteremia in infants hospitalized in neonatal intensive care units (NICUs), 21 bloodstream isolates from 21 infants were genotyped and other 21 infants without MRSA bacteremia were matched for a case-control study. Two genotypes (A and C) were identified by pulsed-field gel electrophoresis and three genotypes (I, II and III) by infrequent-restriction-site polymerase chain reaction. Genotype C-III in 9 isolates and genotype A-I in 7 isolates were the two most common genotypes. The presence of skin infection at onset, prolonged prior duration of central venous catheter indwelling and prolonged hospital stay were significantly associated with MRSA bacteremia in these infants. With multiple logistic regression analysis, the presence of skin infection at onset was the only significant risk factor of MRSA bacteremia, with an odds ratio of 2...","publication_name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi"},"translated_abstract":"To assess the relatedness of methicillin-resistant Staphylococcus aureus (MRSA) isolates and to identify the risk factors for the acquisition of MRSA bacteremia in infants hospitalized in neonatal intensive care units (NICUs), 21 bloodstream isolates from 21 infants were genotyped and other 21 infants without MRSA bacteremia were matched for a case-control study. Two genotypes (A and C) were identified by pulsed-field gel electrophoresis and three genotypes (I, II and III) by infrequent-restriction-site polymerase chain reaction. Genotype C-III in 9 isolates and genotype A-I in 7 isolates were the two most common genotypes. The presence of skin infection at onset, prolonged prior duration of central venous catheter indwelling and prolonged hospital stay were significantly associated with MRSA bacteremia in these infants. With multiple logistic regression analysis, the presence of skin infection at onset was the only significant risk factor of MRSA bacteremia, with an odds ratio of 2...","internal_url":"https://www.academia.edu/14115156/Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study","translated_internal_url":"","created_at":"2015-07-16T07:34:06.714-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292309,"work_id":14115156,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":607516,"email":"p***n@cgmh.org.tw","display_order":0,"name":"Tzou-yien Lin","title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study"},{"id":3292356,"work_id":14115156,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":530665,"email":"p***n@adm.cgmh.org.tw","display_order":4194304,"name":"Tzou-yien Lin","title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study"},{"id":3293143,"work_id":14115156,"tagging_user_id":33115704,"tagged_user_id":33121704,"co_author_invite_id":818623,"email":"s***i@gmail.com","display_order":6291456,"name":"Lin-hui Su","title":"Methicillin-resistant Staphylococcus aureus bacteremia in neonatal intensive care units: genotyping analysis and case-control study"}],"downloadable_attachments":[],"slug":"Methicillin_resistant_Staphylococcus_aureus_bacteremia_in_neonatal_intensive_care_units_genotyping_analysis_and_case_control_study","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115155"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115155/Large_Isoform_of_Mammalian_Relative_of_DnaJ_is_a_Major_Determinant_of_Human_Susceptibility_to_HIV_1_Infection"><img alt="Research paper thumbnail of Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection" class="work-thumbnail" src="https://attachments.academia-assets.com/44588948/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115155/Large_Isoform_of_Mammalian_Relative_of_DnaJ_is_a_Major_Determinant_of_Human_Susceptibility_to_HIV_1_Infection">Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection</a></div><div class="wp-workCard_item"><span>EBioMedicine</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of MRJ-L in monocyte-derived macrophages was significantly higher in HIV-infected individuals (n = 31) than their uninfected counterparts (n = 27) (p = 0.009). Fifty male homosexual subjects (20 of them are HIV-1 positive) were further recruited to examine the association between MRJ-L levels and occurrence of HIV infection. Bayesian multiple logistic regression revealed that playing a receptive role and increased levels of MRJ-L in macrophages were two risk factors for HIV-1 infection. A 1% rise in MRJ-L expression was associated with a 1.13 fold (95% CrI 1.06-1.29) increase in odds of contracting HIV-1 infection. Ex vivo experiments revealed that MRJ-L facilitated Vpr-dependent nuclear loca...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="339f34a4a157f8fba9a53f538ee9c50b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588948,"asset_id":14115155,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588948/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115155"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115155"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115155; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115155]").text(description); $(".js-view-count[data-work-id=14115155]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115155; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115155']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115155, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "339f34a4a157f8fba9a53f538ee9c50b" } } $('.js-work-strip[data-work-id=14115155]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115155,"title":"Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection","translated_title":"","metadata":{"abstract":"Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of MRJ-L in monocyte-derived macrophages was significantly higher in HIV-infected individuals (n = 31) than their uninfected counterparts (n = 27) (p = 0.009). Fifty male homosexual subjects (20 of them are HIV-1 positive) were further recruited to examine the association between MRJ-L levels and occurrence of HIV infection. Bayesian multiple logistic regression revealed that playing a receptive role and increased levels of MRJ-L in macrophages were two risk factors for HIV-1 infection. A 1% rise in MRJ-L expression was associated with a 1.13 fold (95% CrI 1.06-1.29) increase in odds of contracting HIV-1 infection. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115154"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115154/Molecular_diagnosis_and_clinical_presentations_of_enteroviral_infections_in_Taipei_during_the_2008_epidemic"><img alt="Research paper thumbnail of Molecular diagnosis and clinical presentations of enteroviral infections in Taipei during the 2008 epidemic" class="work-thumbnail" src="https://attachments.academia-assets.com/44588935/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115154/Molecular_diagnosis_and_clinical_presentations_of_enteroviral_infections_in_Taipei_during_the_2008_epidemic">Molecular diagnosis and clinical presentations of enteroviral infections in Taipei during the 2008 epidemic</a></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In 2008, an epidemic of enterovirus (EV) infection caused hand, foot, and mouth disease (HFMD) an...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In 2008, an epidemic of enterovirus (EV) infection caused hand, foot, and mouth disease (HFMD) and herpangina in children in Taiwan, and some of them died. To establish an early detection and effective management for children with EV71 infection, sensitive molecular diagnostic methods were applied from May to July 2008. We used virus isolation, EV71 real-time reverse-transcription polymerase chain reaction (RT-PCR), and viral protein 1 (VP1) RT-PCR followed by direct sequencing to detect EV71 and the other EVs in the infected outpatient or inpatient children. Clinical presentations of children infected with EV71 and other EVs were compared. From May 2008 to July 2008, 255 swabs were tested by both PCR diagnostic methods. Based on the viral isolation results, the sensitivities of EV71 real-time RT-PCR and VP1 RT-PCR followed by direct sequencing were 71% and 86%, respectively. Among the 221 children who were enrolled for clinical analysis, 73% (161 of 221) had herpangina, and 27% (60...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8a150fee6f40ce9ee4c98fd4b96ff4a5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588935,"asset_id":14115154,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588935/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115154"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115154"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115154; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115154]").text(description); $(".js-view-count[data-work-id=14115154]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115154; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115154']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115154, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8a150fee6f40ce9ee4c98fd4b96ff4a5" } } $('.js-work-strip[data-work-id=14115154]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115154,"title":"Molecular diagnosis and clinical presentations of enteroviral infections in Taipei during the 2008 epidemic","translated_title":"","metadata":{"abstract":"In 2008, an epidemic of enterovirus (EV) infection caused hand, foot, and mouth disease (HFMD) and herpangina in children in Taiwan, and some of them died. 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src="https://attachments.academia-assets.com/38207868/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115153/HLA_A33_Is_Associated_With_Susceptibility_to_Enterovirus_71_Infection">HLA-A33 Is Associated With Susceptibility to Enterovirus 71 Infection</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">OBJECTIVE.Enterovirus 71 has caused large epidemics of disease, resulting in many fatalities and ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">OBJECTIVE.Enterovirus 71 has caused large epidemics of disease, resulting in many fatalities and severe sequelae, in Taiwan and some other countries. In this study, host genetic factors were investigated to link susceptibility to and clinical severity of enterovirus 71 infections. METHODS.We enrolled 219 enterovirus 71 case subjects and 97 control children. HLA typing was performed with sequence-specific primers, and polymorphisms</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bb22c7a379b25d09eb7e62247df0c5ac" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38207868,"asset_id":14115153,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38207868/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115153"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115153"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115153; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115153]").text(description); $(".js-view-count[data-work-id=14115153]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115153; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115153']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115153, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bb22c7a379b25d09eb7e62247df0c5ac" } } $('.js-work-strip[data-work-id=14115153]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115153,"title":"HLA-A33 Is Associated With Susceptibility to Enterovirus 71 Infection","translated_title":"","metadata":{"abstract":"OBJECTIVE.Enterovirus 71 has caused large epidemics of disease, resulting in many fatalities and severe sequelae, in Taiwan and some other countries. 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manifestations and quantitative analysis of virus load in Taiwanese children with Epstein-Barr virus-associated infectious mononucleosis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115152/Clinical_manifestations_and_quantitative_analysis_of_virus_load_in_Taiwanese_children_with_Epstein_Barr_virus_associated_infectious_mononucleosis">Clinical manifestations and quantitative analysis of virus load in Taiwanese children with Epstein-Barr virus-associated infectious mononucleosis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background and Purpose: To delineate the clinical manifestations in different age groups and to d...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background and Purpose: To delineate the clinical manifestations in different age groups and to define the viral load in patients with Epstein-Barr virus-associated infectious mononucleosis (EBV-associated IM). Methods: We reviewed data on 69 children with EBV-associated IM from November 2001 to October 2005. Clinical features were evaluated among four age groups: &lt;3 years, 3 to 5 years, 6 to 9</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115152"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115152"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115152; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115152]").text(description); $(".js-view-count[data-work-id=14115152]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115152; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115152']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115152, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115152]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115152,"title":"Clinical manifestations and quantitative analysis of virus load in Taiwanese children with Epstein-Barr virus-associated infectious mononucleosis","translated_title":"","metadata":{"abstract":"Background and Purpose: To delineate the clinical manifestations in different age groups and to define the viral load in patients with Epstein-Barr virus-associated infectious mononucleosis (EBV-associated IM). 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class="js-work-more-abstract-truncated">+ CD25 + regulatory T cells and their phenotypic expression in peripheral blood of children with ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">+ CD25 + regulatory T cells and their phenotypic expression in peripheral blood of children with active and non-active juvenile idio- pathic arthritis (JIA) and healthy controls, to determine if their frequency or phenotypic expression is involved in the immunoregulation of this disease. Methods: From October 2004 to October 2005, 55 JIA patients and 55 age- and gender-matched healthy controls</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115151"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115151"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115151; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115151]").text(description); $(".js-view-count[data-work-id=14115151]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115151; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115151']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115151, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115151]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115151,"title":"Frequency and phenotypic analysis of CD4+CD25+ regulatory T cells in children with juvenile idiopathic arthritis","translated_title":"","metadata":{"abstract":"+ CD25 + regulatory T cells and their phenotypic expression in peripheral blood of children with active and non-active juvenile idio- pathic arthritis (JIA) and healthy controls, to determine if their frequency or phenotypic expression is involved in the immunoregulation of this disease. 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However, there is limited epidemiological data about RSV infection in Taiwan. This study aimed to investigate the clinical, epidemiological, virological, and economical aspects of RSV infections in Taiwan. Methods: We collected data of children with positive RSV respiratory specimens at the Laboratory</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115150"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115150"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115150; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115150]").text(description); $(".js-view-count[data-work-id=14115150]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115150; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115150']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115150, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115150]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115150,"title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden","translated_title":"","metadata":{"abstract":"Background and Purpose: Respiratory syncytial virus (RSV) is an important pathogen in children less than 2 years old. 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Methods: We collected data of children with positive RSV respiratory specimens at the Laboratory","internal_url":"https://www.academia.edu/14115150/Epidemiology_of_respiratory_syncytial_virus_infection_in_northern_Taiwan_2001_2005_seasonality_clinical_characteristics_and_disease_burden","translated_internal_url":"","created_at":"2015-07-16T07:34:05.902-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292431,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818511,"email":"c***u@ntu.edu.tw","display_order":0,"name":"Chun-yi Lu","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292543,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":43181325,"co_author_invite_id":818512,"email":"c***u@ntuh.gov.tw","display_order":4194304,"name":"Chun-yi Lu","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292681,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818517,"email":"p***g@ntumc.org","display_order":6291456,"name":"Ping-ing Lee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292711,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":297031361,"co_author_invite_id":818518,"email":"p***g@ntu.edu.tw","display_order":7340032,"name":"Ping-ing Lee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292882,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818534,"email":"s***7@ms38.hinet.net","display_order":7864320,"name":"Pei-lan Shao","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3292955,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818544,"email":"y***u@ntu.edu.tw","display_order":8126464,"name":"Chin-yun Lee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"},{"id":3293001,"work_id":14115150,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818555,"email":"p***8@ntnu.edu.tw","display_order":8257536,"name":"Ping- Inglee","title":"Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 — seasonality, clinical characteristics, and disease burden"}],"downloadable_attachments":[],"slug":"Epidemiology_of_respiratory_syncytial_virus_infection_in_northern_Taiwan_2001_2005_seasonality_clinical_characteristics_and_disease_burden","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[{"id":57433,"name":"Seasonality","url":"https://www.academia.edu/Documents/in/Seasonality"},{"id":208136,"name":"Respiratory Syncytial Virus","url":"https://www.academia.edu/Documents/in/Respiratory_Syncytial_Virus"},{"id":263029,"name":"Intensive Care Unit","url":"https://www.academia.edu/Documents/in/Intensive_Care_Unit"},{"id":883945,"name":"Chronic lung disease","url":"https://www.academia.edu/Documents/in/Chronic_lung_disease"},{"id":1505497,"name":"Endotracheal intubation","url":"https://www.academia.edu/Documents/in/Endotracheal_intubation"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115149"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115149/Stenotrophomonas_maltophilia_bacteremia_in_pediatric_patients_a_10_year_analysis"><img alt="Research paper thumbnail of Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115149/Stenotrophomonas_maltophilia_bacteremia_in_pediatric_patients_a_10_year_analysis">Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Results: In total, 32 episodes (31 patients) of S. maltophilia bacteremia were reviewed. The aver...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Results: In total, 32 episodes (31 patients) of S. maltophilia bacteremia were reviewed. The average rate of nosocomial bloodstream infection was 8.3 episodes per 100,000 patient-days, and an average of 6.4% of them were caused by S. maltophilia. Malignancy was the most common underlying disease (32%). Six episodes of S. maltophilia bacteremia had soft tissue involvement, and only 1 of</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115149"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115149"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115149; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115149]").text(description); $(".js-view-count[data-work-id=14115149]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115149; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115149']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115149, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115149]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115149,"title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis","translated_title":"","metadata":{"abstract":"Results: In total, 32 episodes (31 patients) of S. maltophilia bacteremia were reviewed. 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Six episodes of S. maltophilia bacteremia had soft tissue involvement, and only 1 of","internal_url":"https://www.academia.edu/14115149/Stenotrophomonas_maltophilia_bacteremia_in_pediatric_patients_a_10_year_analysis","translated_internal_url":"","created_at":"2015-07-16T07:34:05.728-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292428,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818511,"email":"c***u@ntu.edu.tw","display_order":0,"name":"Chun-yi Lu","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3292540,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":43181325,"co_author_invite_id":818512,"email":"c***u@ntuh.gov.tw","display_order":4194304,"name":"Chun-yi Lu","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3292679,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818517,"email":"p***g@ntumc.org","display_order":6291456,"name":"Ping-ing Lee","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3292710,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":297031361,"co_author_invite_id":818518,"email":"p***g@ntu.edu.tw","display_order":7340032,"name":"Ping-ing Lee","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3292736,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":511154,"email":"h***n@ha.ntu.edu.tw","display_order":7864320,"name":"Po-ren Hsueh","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3292745,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":252068985,"co_author_invite_id":511155,"email":"h***n@ntu.edu.tw","display_order":8126464,"name":"Po-ren Hsueh","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3292954,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818544,"email":"y***u@ntu.edu.tw","display_order":8257536,"name":"Chin-yun Lee","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3293000,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818555,"email":"p***8@ntnu.edu.tw","display_order":8323072,"name":"Ping- Inglee","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"},{"id":3293055,"work_id":14115149,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818580,"email":"p***u@tzuchi.com.tw","display_order":8355840,"name":"Ping-sheng Wu","title":"Stenotrophomonas maltophilia bacteremia in pediatric patients — a 10-year analysis"}],"downloadable_attachments":[],"slug":"Stenotrophomonas_maltophilia_bacteremia_in_pediatric_patients_a_10_year_analysis","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology"},{"id":6947,"name":"Medical Microbiology","url":"https://www.academia.edu/Documents/in/Medical_Microbiology"},{"id":94123,"name":"Multidrug Resistance","url":"https://www.academia.edu/Documents/in/Multidrug_Resistance"},{"id":102583,"name":"Drug Resistance","url":"https://www.academia.edu/Documents/in/Drug_Resistance"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":631028,"name":"Soft Tissue","url":"https://www.academia.edu/Documents/in/Soft_Tissue"},{"id":860622,"name":"Antimicrobial photodynamic therapy","url":"https://www.academia.edu/Documents/in/Antimicrobial_photodynamic_therapy"},{"id":906563,"name":"Central Venous Catheter","url":"https://www.academia.edu/Documents/in/Central_Venous_Catheter"},{"id":1680434,"name":"Mortality rate","url":"https://www.academia.edu/Documents/in/Mortality_rate"}],"urls":[{"id":4982275,"url":"http://www.jmii.org/content/pdf/v39n2p144.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115148"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115148/Clinical_characteristics_of_children_with_influenza_A_virus_infection_requiring_hospitalization"><img alt="Research paper thumbnail of Clinical characteristics of children with influenza A virus infection requiring hospitalization" class="work-thumbnail" src="https://attachments.academia-assets.com/44588970/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115148/Clinical_characteristics_of_children_with_influenza_A_virus_infection_requiring_hospitalization">Clinical characteristics of children with influenza A virus infection requiring hospitalization</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">From September 1997 to March 2002, a total of 84 children were admitted to Chang Gung Children&#3...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">From September 1997 to March 2002, a total of 84 children were admitted to Chang Gung Children&#39;s Hospital due to influenza A virus infection. Influenza A virus infection was documented in 61 cases by viral isolation from throat and in 23 cases by serologic studies. The mean age of patients was 43.8 months, ranging from 20 days to 16 years.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b9834f70305276de5734ed4550b396f9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588970,"asset_id":14115148,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588970/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&st=MTczMjQ1OTI4NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115148"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115148"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115148; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115148]").text(description); $(".js-view-count[data-work-id=14115148]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115148; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115148']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115148, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b9834f70305276de5734ed4550b396f9" } } $('.js-work-strip[data-work-id=14115148]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115148,"title":"Clinical characteristics of children with influenza A virus infection requiring hospitalization","translated_title":"","metadata":{"abstract":"From September 1997 to March 2002, a total of 84 children were admitted to Chang Gung Children\u0026#39;s Hospital due to influenza A virus infection. 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href="https://www.academia.edu/14115146/Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease"><img alt="Research paper thumbnail of Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115146/Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease">Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JoukouWang">Jou-kou Wang</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ChangChinhao">Chin-hao Chang</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/ChunanChen">Chun-an Chen</a></span></div><div class="wp-workCard_item"><span>Journal of the Formosan Medical Association = Taiwan yi zhi</span><span>, Jan 21, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Kawasaki disease (KD) is the most common pediatric vasculitis. The study aimed to identify the ri...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Kawasaki disease (KD) is the most common pediatric vasculitis. The study aimed to identify the risk factors of intravenous immunoglobulin (IVIG) unresponsiveness from the initial clinical parameters of the Taiwanese KD patients. We enrolled 248 KD (development dataset: 181, validation: 67) patients who received IVIG within 10 days after fever onset. IVIG unresponsiveness was defined by persistent fever beyond 24 hours after IVIG or recrudescent fever with KD symptoms. From the development dataset (181 patients), IVIG unresponsiveness was noted in 22 patients (12.1%). The preIVIG levels of albumin, percentage of neutrophils, and positive lymphadenopathy were identified with highest risk for IVIG unresponsiveness. These three variables were used to construct a three-variable logistic regression model, which yielded an area under the receiver-operating-characteristics curve of 0.87. These three variables were further used to generate a composite scoring model (Formosa score) which yiel...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115146"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115146"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115146; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115146]").text(description); $(".js-view-count[data-work-id=14115146]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115146; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115146']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115146, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115146]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115146,"title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease","translated_title":"","metadata":{"abstract":"Kawasaki disease (KD) is the most common pediatric vasculitis. 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These three variables were used to construct a three-variable logistic regression model, which yielded an area under the receiver-operating-characteristics curve of 0.87. These three variables were further used to generate a composite scoring model (Formosa score) which yiel...","internal_url":"https://www.academia.edu/14115146/Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease","translated_internal_url":"","created_at":"2015-07-16T07:34:05.235-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292717,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":721755,"email":"w***h@ntu.edu.tw","display_order":0,"name":"Mei-hwan Wu","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":3292754,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":36647501,"co_author_invite_id":818520,"email":"j***w@ntuh.gov.tw","display_order":4194304,"name":"Jou-kou Wang","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":3292757,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":37027739,"co_author_invite_id":818521,"email":"c***o@ntuh.gov.tw","display_order":6291456,"name":"Chin-hao Chang","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":3293085,"work_id":14115146,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":818594,"email":"j***y@taigen.com","display_order":7340032,"name":"M. Lin","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":7814003,"work_id":14115146,"tagging_user_id":36647501,"tagged_user_id":36595650,"co_author_invite_id":null,"email":"c***a@ntu.edu.tw","affiliation":"National Taiwan University","display_order":7864320,"name":"Chun-an Chen","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"},{"id":7814004,"work_id":14115146,"tagging_user_id":36647501,"tagged_user_id":null,"co_author_invite_id":1744818,"email":"h***u@gmail.com","display_order":8126464,"name":"Hsin-min Liu","title":"Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease"}],"downloadable_attachments":[],"slug":"Risk_factors_and_derived_formosa_score_for_intravenous_immunoglobulin_unresponsiveness_in_Taiwanese_children_with_Kawasaki_disease","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115145"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115145/Effect_of_intravenous_immunoglobulin_for_neonates_with_severe_enteroviral_infections_with_emphasis_on_the_timing_of_administration"><img alt="Research paper thumbnail of Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration" class="work-thumbnail" src="https://attachments.academia-assets.com/44588958/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115145/Effect_of_intravenous_immunoglobulin_for_neonates_with_severe_enteroviral_infections_with_emphasis_on_the_timing_of_administration">Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration</a></div><div class="wp-workCard_item"><span>Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infecti...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infections are still controversial. To evaluate whether timing of IVIG administration might affect clinical outcomes of neonates with severe enteroviral infections. We retrospectively analyzed 67 neonates with culture-confirmed severe enteroviral infection, defined as hepatitis with coagulopathy and thrombocytopenia. Clinical features, outcomes and the usage of IVIG therapy were collected and analyzed. IVIG administered within 3 days of illness onset was classified as early IVIG therapy. Of the 67 cases, 38 (57%) were male, 27 (40%) were premature, 57 (85%) had disease onset within 7 days of life and all but 2 cases were caused by coxsackievirus B group. Ten infants (15%) had clinically evident myocarditis. 41 infants (61%) received IVIG therapy and 29 were early IVIG therapy. Fifteen infants (22%) eventually died, without IVIG therapy for 7 infants. The deceased had a significantly higher peak...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bb17763ed6ee88b4531ffb28ca4c07f7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588958,"asset_id":14115145,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588958/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115145"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115145"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115145; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115145]").text(description); $(".js-view-count[data-work-id=14115145]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115145; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115145']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115145, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bb17763ed6ee88b4531ffb28ca4c07f7" } } $('.js-work-strip[data-work-id=14115145]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115145,"title":"Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration","translated_title":"","metadata":{"abstract":"The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infections are still controversial. 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The deceased had a significantly higher peak...","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology"},"translated_abstract":"The benefits of intravenous immunoglobulin (IVIG) therapy for severe neonatal enterovirus infections are still controversial. To evaluate whether timing of IVIG administration might affect clinical outcomes of neonates with severe enteroviral infections. We retrospectively analyzed 67 neonates with culture-confirmed severe enteroviral infection, defined as hepatitis with coagulopathy and thrombocytopenia. Clinical features, outcomes and the usage of IVIG therapy were collected and analyzed. IVIG administered within 3 days of illness onset was classified as early IVIG therapy. 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The deceased had a significantly higher peak...","internal_url":"https://www.academia.edu/14115145/Effect_of_intravenous_immunoglobulin_for_neonates_with_severe_enteroviral_infections_with_emphasis_on_the_timing_of_administration","translated_internal_url":"","created_at":"2015-07-16T07:34:05.083-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292300,"work_id":14115145,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":607516,"email":"p***n@cgmh.org.tw","display_order":0,"name":"Tzou-yien Lin","title":"Effect of intravenous immunoglobulin for neonates with severe enteroviral infections with emphasis on the timing of administration"},{"id":3292347,"work_id":14115145,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":530665,"email":"p***n@adm.cgmh.org.tw","display_order":4194304,"name":"Tzou-yien Lin","title":"Effect of 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thumbnail of Central venous catheter-associated bloodstream infections in pediatric hematology-oncology patients and effectiveness of antimicrobial lock therapy" class="work-thumbnail" src="https://attachments.academia-assets.com/44588983/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115144/Central_venous_catheter_associated_bloodstream_infections_in_pediatric_hematology_oncology_patients_and_effectiveness_of_antimicrobial_lock_therapy">Central venous catheter-associated bloodstream infections in pediatric hematology-oncology patients and effectiveness of antimicrobial lock therapy</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span><span>, Jan 10, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-on...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-oncology patients. This study aimed to analyze the prevalence of CLABSI and the effectiveness of antimicrobial lock therapy (ALT) in pediatric patients. BSIs of all pediatric hematology-oncology patients admitted to a children&#39;s hospital between January 2009 and December 2013 were reviewed. The United States National Healthcare Safety Network and Infectious Diseases Society of America guidelines were used to define CLABSI and catheter-related BSI (CRBSI). The incidence, laboratory and microbiology characteristics, poor outcome, and effectiveness of ALT were analyzed. There were 246 cases of CLABSI in 146 patients (mean age, 10.0 years), including 66 (26.8%) cases of CRBSI. The incidence of CLABSI was 4.49/1000 catheter-days, and the infection was responsible for 32.9% of the complications these patients developed and 9.3% of contributable mortality. Patients with acute myeloid leukemia...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="393a7d7419d5332406a60feda6d83fc6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588983,"asset_id":14115144,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588983/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115144"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115144"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115144; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115144]").text(description); $(".js-view-count[data-work-id=14115144]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115144; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115144']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115144, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "393a7d7419d5332406a60feda6d83fc6" } } $('.js-work-strip[data-work-id=14115144]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115144,"title":"Central venous catheter-associated bloodstream infections in pediatric hematology-oncology patients and effectiveness of antimicrobial lock therapy","translated_title":"","metadata":{"abstract":"Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-oncology patients. This study aimed to analyze the prevalence of CLABSI and the effectiveness of antimicrobial lock therapy (ALT) in pediatric patients. BSIs of all pediatric hematology-oncology patients admitted to a children\u0026#39;s hospital between January 2009 and December 2013 were reviewed. The United States National Healthcare Safety Network and Infectious Diseases Society of America guidelines were used to define CLABSI and catheter-related BSI (CRBSI). The incidence, laboratory and microbiology characteristics, poor outcome, and effectiveness of ALT were analyzed. There were 246 cases of CLABSI in 146 patients (mean age, 10.0 years), including 66 (26.8%) cases of CRBSI. The incidence of CLABSI was 4.49/1000 catheter-days, and the infection was responsible for 32.9% of the complications these patients developed and 9.3% of contributable mortality. Patients with acute myeloid leukemia...","publication_date":{"day":10,"month":1,"year":2014,"errors":{}},"publication_name":"Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi"},"translated_abstract":"Central line-associated bloodstream infection (CLABSI) is a serious complication in hematology-oncology patients. This study aimed to analyze the prevalence of CLABSI and the effectiveness of antimicrobial lock therapy (ALT) in pediatric patients. BSIs of all pediatric hematology-oncology patients admitted to a children\u0026#39;s hospital between January 2009 and December 2013 were reviewed. The United States National Healthcare Safety Network and Infectious Diseases Society of America guidelines were used to define CLABSI and catheter-related BSI (CRBSI). The incidence, laboratory and microbiology characteristics, poor outcome, and effectiveness of ALT were analyzed. 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/></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115143/Campylobacter_enteritis_in_children_in_northern_Taiwan_a_7_year_experience">Campylobacter enteritis in children in northern Taiwan--a 7-year experience</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/YuChiaHsieh">Yu Chia Hsieh</a></span></div><div class="wp-workCard_item"><span>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Campylobacter infection is recognized as a major cause of acute enteritis in humans. The clinical...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Campylobacter infection is recognized as a major cause of acute enteritis in humans. The clinical characteristics may vary in different countries. This study investigated the clinical manifestations of pediatric Campylobacter enteritis in a medical center in northern Taiwan. This was a retrospective review of Campylobacter enteritis infections at National Taiwan University Hospital, Taipei, Taiwan, from January 2000 to December 2006. All children who tested positive for Campylobacter, isolated from stool samples, were included in the study. Data collected and evaluated included the species of Campylobacter, age, gender, underlying disease, travel history, clinical manifestations and laboratory data. A total of 104 patients had enteric campylobacteriosis. Campylobacter coli was grown from 24 patients (23.1%), while Campylobacter jejuni was found in 80 patients (76.9%). More than half of the infections (60.6%) occurred in children less than 5 years old. The male-to-female ratio was 2....</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115143"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115143"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115143; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115143]").text(description); $(".js-view-count[data-work-id=14115143]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115143; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115143']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115143, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115143]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115143,"title":"Campylobacter enteritis in children in northern Taiwan--a 7-year experience","translated_title":"","metadata":{"abstract":"Campylobacter infection is recognized as a major cause of acute enteritis in humans. 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The male-to-female ratio was 2....","publication_date":{"day":null,"month":null,"year":2008,"errors":{}},"publication_name":"Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi"},"translated_abstract":"Campylobacter infection is recognized as a major cause of acute enteritis in humans. The clinical characteristics may vary in different countries. This study investigated the clinical manifestations of pediatric Campylobacter enteritis in a medical center in northern Taiwan. This was a retrospective review of Campylobacter enteritis infections at National Taiwan University Hospital, Taipei, Taiwan, from January 2000 to December 2006. All children who tested positive for Campylobacter, isolated from stool samples, were included in the study. Data collected and evaluated included the species of Campylobacter, age, gender, underlying disease, travel history, clinical manifestations and laboratory data. A total of 104 patients had enteric campylobacteriosis. 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infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115142/Lack_of_association_between_infection_with_a_novel_human_coronavirus_HCoV_HCoV_NH_and_Kawasaki_disease_in_Taiwan">Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan</a></div><div class="wp-workCard_item"><span>The Journal of infectious diseases</span><span>, Jan 15, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We investigated whether infection with a novel human coronavirus (HCoV), called &quot;New Haven c...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We investigated whether infection with a novel human coronavirus (HCoV), called &quot;New Haven coronavirus&quot; (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115142"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115142"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115142; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115142]").text(description); $(".js-view-count[data-work-id=14115142]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115142; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115142']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115142, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115142]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115142,"title":"Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan","translated_title":"","metadata":{"abstract":"We investigated whether infection with a novel human coronavirus (HCoV), called \u0026quot;New Haven coronavirus\u0026quot; (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.","publication_date":{"day":15,"month":1,"year":2006,"errors":{}},"publication_name":"The Journal of infectious diseases"},"translated_abstract":"We investigated whether infection with a novel human coronavirus (HCoV), called \u0026quot;New Haven coronavirus\u0026quot; (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.","internal_url":"https://www.academia.edu/14115142/Lack_of_association_between_infection_with_a_novel_human_coronavirus_HCoV_HCoV_NH_and_Kawasaki_disease_in_Taiwan","translated_internal_url":"","created_at":"2015-07-16T07:34:04.754-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33115704,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3292719,"work_id":14115142,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":721755,"email":"w***h@ntu.edu.tw","display_order":0,"name":"Mei-hwan Wu","title":"Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan"},{"id":3292748,"work_id":14115142,"tagging_user_id":33115704,"tagged_user_id":null,"co_author_invite_id":695744,"email":"p***n@ntu.edu.tw","display_order":4194304,"name":"Pei-jer Chen","title":"Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan"}],"downloadable_attachments":[],"slug":"Lack_of_association_between_infection_with_a_novel_human_coronavirus_HCoV_HCoV_NH_and_Kawasaki_disease_in_Taiwan","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":33115704,"first_name":"Luan-yin","middle_initials":null,"last_name":"Chang","page_name":"LuanyinChang","domain_name":"taiwan","created_at":"2015-07-16T07:22:59.784-07:00","display_name":"Luan-yin Chang","url":"https://taiwan.academia.edu/LuanyinChang"},"attachments":[],"research_interests":[{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":94451,"name":"Taiwan","url":"https://www.academia.edu/Documents/in/Taiwan"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":210665,"name":"Infectious","url":"https://www.academia.edu/Documents/in/Infectious"},{"id":837636,"name":"SERUM","url":"https://www.academia.edu/Documents/in/SERUM"},{"id":1305891,"name":"Coronavirus","url":"https://www.academia.edu/Documents/in/Coronavirus"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115141"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115141/Childhood_severe_acute_respiratory_syndrome_in_Taiwan_and_how_to_differentiate_it_from_childhood_influenza_infection"><img alt="Research paper thumbnail of Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115141/Childhood_severe_acute_respiratory_syndrome_in_Taiwan_and_how_to_differentiate_it_from_childhood_influenza_infection">Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection</a></div><div class="wp-workCard_item"><span>Archives of pediatrics & adolescent medicine</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed sev...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed severe acute respiratory syndrome (SARS) vs those of children with influenza to differentiate the 2 diseases. Patients 20 years or younger with clinical, epidemiological, and laboratory evidence of SARS from March to July 2003 vs children with virus culture-confirmed influenza in a 1:1 age- and sex-matched control group. Rates of symptoms, abnormal laboratory data, and outcomes of recovery, sequelae, or death. The 15 SARS patients (9 girls and 6 boys) had a median age of 17 years (age range, 4-20 years). Nine patients (60%) were infected through household contact, 4 (27%) nosocomially, 1 (7%) through contact with a neighbor, and 1 (7%) after returning from Hong Kong. All 15 patients had fever, 3 (20%) had chills, and 11 (73%) had cough. Only 1 patient (7%) had sputum production; 1 (7%) had rhinorrhea. At presentation, 5 patients (33%) had leukopenia, 6 (40%) had lymphopenia, and 5 (33%) had...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115141"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115141"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115141; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115141]").text(description); $(".js-view-count[data-work-id=14115141]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115141; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115141']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115141, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115141]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115141,"title":"Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection","translated_title":"","metadata":{"abstract":"To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed severe acute respiratory syndrome (SARS) vs those of children with influenza to differentiate the 2 diseases. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115140"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115140/Transmission_and_clinical_features_of_enterovirus_71_infections_in_household_contacts_in_Taiwan"><img alt="Research paper thumbnail of Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan" class="work-thumbnail" src="https://attachments.academia-assets.com/44588956/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115140/Transmission_and_clinical_features_of_enterovirus_71_infections_in_household_contacts_in_Taiwan">Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan</a></div><div class="wp-workCard_item"><span>JAMA</span><span>, Jan 14, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Although enterovirus 71 has caused epidemics associated with significant morbidity and mortality,...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Although enterovirus 71 has caused epidemics associated with significant morbidity and mortality, its transmission has not been thoroughly investigated. To investigate enterovirus 71 transmission and determine clinical outcomes within households. Prospective family cohort study to investigate patients at a children&#39;s hospital in Taiwan and family members of these patients who had signs and symptoms suggestive of enterovirus 71 between February 2001 and August 2002. Patients and household members underwent clinical evaluations, virological studies, questionnaire-based interviews, and were followed up for 6 months. Enterovirus 71 infection, defined as a positive viral culture from a throat or rectal swab, or the presence of IgM or a 4-fold increase in neutralizing antibody in serum; and clinical syndromes, defined as asymptomatic; uncomplicated symptomatic; and complicated; with unfavorable outcomes of sequelae or death. Ninety-four families (433 family members) had at least 1 fam...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b49a0f6e61039531b50a1e5f54eb15fa" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588956,"asset_id":14115140,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588956/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115140"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115140"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115140; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115140]").text(description); $(".js-view-count[data-work-id=14115140]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115140; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115140']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115140, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b49a0f6e61039531b50a1e5f54eb15fa" } } $('.js-work-strip[data-work-id=14115140]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115140,"title":"Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan","translated_title":"","metadata":{"abstract":"Although enterovirus 71 has caused epidemics associated with significant morbidity and mortality, its transmission has not been thoroughly investigated. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115139"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115139/Influenza_in_Taiwan_seasonality_and_vaccine_strain_match"><img alt="Research paper thumbnail of Influenza in Taiwan: seasonality and vaccine strain match" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115139/Influenza_in_Taiwan_seasonality_and_vaccine_strain_match">Influenza in Taiwan: seasonality and vaccine strain match</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/YuChiaHsieh">Yu Chia Hsieh</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This article explores seasonality, epidemiology and dominant epidemic strains of influenza in Tai...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This article explores seasonality, epidemiology and dominant epidemic strains of influenza in Taiwan. Surveillance in Taiwan demonstrates that influenza is a disease which occurs throughout the year but has peak activity in winter. Due to the high mutability of influenza virus, effective vaccination is the best strategy for protection. Although the World Health Organization-recommended vaccine compositions usually matched with around</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115139"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115139"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115139; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115139]").text(description); $(".js-view-count[data-work-id=14115139]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115139; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115139']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115139, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14115139]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115139,"title":"Influenza in Taiwan: seasonality and vaccine strain match","translated_title":"","metadata":{"abstract":"This article explores seasonality, epidemiology and dominant epidemic strains of influenza in Taiwan. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14115138"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14115138/Status_of_cellular_rather_than_humoral_immunity_is_correlated_with_clinical_outcome_of_enterovirus_71"><img alt="Research paper thumbnail of Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71" class="work-thumbnail" src="https://attachments.academia-assets.com/44588957/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14115138/Status_of_cellular_rather_than_humoral_immunity_is_correlated_with_clinical_outcome_of_enterovirus_71">Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LuChunyi">Chun-yi Lu</a></span></div><div class="wp-workCard_item"><span>Pediatric research</span><span>, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We valuated specific cellular and humoral immune response of cases of enterovirus 71 (EV71) infec...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We valuated specific cellular and humoral immune response of cases of enterovirus 71 (EV71) infection and correlated immune response with clinical outcome. After obtaining informed consent, we enrolled 30 EV71 cases including 7 cases with brainstem encephalitis plus pulmonary edema, 12 cases of CNS (CNS) involvement and 11 uncomplicated cases. We measured antibodies specific to EV71, lymphocyte proliferation response and EV71-stimulated cellular response of Th1/Th2 cytokines and chemokines. The 7 EV71 cases involving brainstem encephalitis plus pulmonary edema had a significantly lower phytohemagglutinin stimulation index than other cases (p = 0.04). After EV71 stimulation of peripheral mononuclear cells, there was a significant increase in cellular Th1 cytokine (gamma-interferon) and proinflammatroy cytokines. However, cases with pulmonary edema had significantly lower cellular gamma-interferon (p = 0.04), lower cellular IL-1beta (p = 0.04), lower cellular IL-6 (p = 0.04), lower ce...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e5a42fe39aec1035c9bbc9fb121be2dd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44588957,"asset_id":14115138,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44588957/download_file?st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&st=MTczMjQ1OTI4NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14115138"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14115138"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14115138; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14115138]").text(description); $(".js-view-count[data-work-id=14115138]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14115138; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14115138']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 14115138, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "e5a42fe39aec1035c9bbc9fb121be2dd" } } $('.js-work-strip[data-work-id=14115138]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14115138,"title":"Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71","translated_title":"","metadata":{"abstract":"We valuated specific cellular and humoral immune response of cases of enterovirus 71 (EV71) infection and correlated immune response with clinical outcome. 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