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Der Optimierungsprozes ist von einem hohen Redundanzgrad in den" /> <meta name="robots" content="noindex" /> <title>Beherrschung von Komplexit盲t in der molekularen Evolution | Peter Schuster - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/69744885/Beherrschung_von_Komplexit%C3%A4t_in_der_molekularen_Evolution" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '48654d67e5106e06fb1e5c9a356c302510d6cfee'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1734498593000); window.Aedu.timeDifference = new Date().getTime() - 1734498593000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Die Evolution von Rna-MolekuLen in vitro wird als Kletterprozes auf einer Fitness-Landschaft visualisiert, die aus molekularen Eigenschaften und Funktionen abgeleitet werden kann. Der Optimierungsprozes ist von einem hohen Redundanzgrad in den Abbildungen von den Polynukleotidsequenzen auf die MolekuLstrukturen GepraGt: Es gibt viel mehr Sequenzen als Strukturen und die Sequenzen, die in dieselbe Struktur falten, sind (beinahe) zufallig im Sequenzraum verteilt. Zwei Konsequenzen dieser Redundanz sind fur die Evolution wichtig: die GestaltraumuBerdeckung durch kleine verbundene Gebiete im Sequenzraum und die Existenz ausgedehnter neutraler Netzwerke. Beide Resultate erklaren zusammen, wie die Natur durch Versuch und Irrtum schnell und effizient Losungen fur komplexe Optimierungsprobleme finden kann, wahrend die Anzahl moglicher Genotypen jede Vorstellung ubersteigt. In Gegenwart neutraler Netzwerke vermeiden Populationen, in evolutionaren Fallen gefangen zu werden, und sie erreichen schlieslich das globale Optimum durch eine zusammengesetzte Dynamik von adaptiven Wanderungen und zufalliger Drift. Aus mathematischer Analyse abgeleitete Resultate werden mit den Resultaten von Computersimulationen und verfugbaren experimentellen Daten konfrontiert.","author":[{"@context":"https://schema.org","@type":"Person","name":"Peter Schuster"}],"contributor":[],"dateCreated":"2022-01-28","dateModified":"2022-01-28","headline":"Beherrschung von Komplexit盲t in der molekularen Evolution","image":"https://a.academia-assets.com/images/blank-paper.jpg","inLanguage":"de","keywords":["Physics"],"publication":"Komplexe Systeme und Nichtlineare Dynamik in Natur und Gesellschaft","publisher":{"@context":"https://schema.org","@type":"Organization","name":"Springer Berlin Heidelberg"},"sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}],"thumbnailUrl":"https://a.academia-assets.com/images/blank-paper.jpg","url":"https://www.academia.edu/69744885/Beherrschung_von_Komplexit%C3%A4t_in_der_molekularen_Evolution"}</script><link rel="stylesheet" media="all" 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Der Optimierungsprozes ist von einem hohen Redundanzgrad in den Abbildungen von den Polynukleotidsequenzen auf die MolekuLstrukturen GepraGt: Es gibt viel mehr Sequenzen als Strukturen und die Sequenzen, die in dieselbe Struktur falten, sind (beinahe) zufallig im Sequenzraum verteilt. Zwei Konsequenzen dieser Redundanz sind fur die Evolution wichtig: die GestaltraumuBerdeckung durch kleine verbundene Gebiete im Sequenzraum und die Existenz ausgedehnter neutraler Netzwerke. Beide Resultate erklaren zusammen, wie die Natur durch Versuch und Irrtum schnell und effizient Losungen fur komplexe Optimierungsprobleme finden kann, wahrend die Anzahl moglicher Genotypen jede Vorstellung ubersteigt. In Gegenwart neutraler Netzwerke vermeiden Populationen, in evolutionaren Fallen gefangen zu werden, und sie erreichen schlieslich das globale Optimum durch eine zusammengesetzte Dynamik von adaptiven Wanderungen und zufalliger Drift. Aus mathematischer Analyse abgeleitete Resultate werden mit den Resultaten von Computersimulationen und verfugbaren experimentellen Daten konfrontiert.","publisher":"Springer Berlin Heidelberg","publication_name":"Komplexe Systeme und Nichtlineare Dynamik in Natur und Gesellschaft"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":null,"language":"de","title":"Beherrschung von Komplexit盲t in der molekularen Evolution","broadcastable":false,"draft":null,"has_indexable_attachment":false,"indexable":true}}["work"]; window.loswp.workCoauthors = [11507755]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "grid"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loginModal = {}; window.loginModal.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="loswp-grid--container"><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-landing_url="https://www.academia.edu/69744885/Beherrschung_von_Komplexit%C3%A4t_in_der_molekularen_Evolution" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="above-fold js-swp-splash-above-fold"><div class="work-card--container js-swp-control-work-card" data-entity-id="69744885"><div class="work-cover--wrapper"><div class="work-cover--container"><div class="work-cover--no-attachment-container js-swp-splash-paper-cover"><div class="work-cover--file-icon-wrapper"><img alt="paper cover icon" src="//a.academia-assets.com/images/single_work_splash/adobe.icon.svg" /></div><div class="work-cover--title js-swp-splash-paper-cover-page-title">Beherrschung von Komplexit盲t in der molekularen Evolution</div><br /><div style="margin-top: 170px"><button class="work-cover--request-pdf-button js-request-pdf-button"><svg style="width: 14px; margin-right: 8px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="envelope" class="svg-inline--fa fa-envelope fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z"></path></svg>Request PDF</button></div></div></div></div><div class="work-card--content"><h1 class="work-card--title">Beherrschung von Komplexit盲t in der molekularen Evolution</h1><div class="work-card--pub-info">Komplexe Systeme und Nichtlineare Dynamik in Natur und Gesellschaft</div><a class="js-profile-link work-card--single-author" data-has-card-for-user="11507755" href="https://independent.academia.edu/PSchuster?swp=tc-au-69744885"><div class="work-card--single-author-photo"><img class="Avatar--circle s65 Avatar--circle s65 Avatar--xxxs" alt="Peter Schuster" shape="circle" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s65_no_pic.png') this.src = '//a.academia-assets.com/images/s65_no_pic.png';" width="65" height="65" src="https://0.academia-photos.com/11507755/5025271/5767664/s65_peter.schuster.jpg" /></div><div class="work-card--author-name-wrapper" style="max-width: 125px; font-weight: 500; color: #4b4b4b;"><div class="u-textTruncate"><span itemprop="author">Peter Schuster</span></div></div></a><script data-card-contents-for-user="11507755" type="text/json">{"id":11507755,"first_name":"Peter","middle_initials":"","last_name":"Schuster","page_name":"PSchuster","domain_name":"independent","created_at":"2014-04-25T18:24:34.245-07:00","display_name":"Peter Schuster","url":"https://independent.academia.edu/PSchuster","photo":"https://0.academia-photos.com/11507755/5025271/5767664/s65_peter.schuster.jpg","has_photo":true,"interests":[{"id":1601,"name":"Teacher Education","url":"https://www.academia.edu/Documents/in/Teacher_Education"},{"id":7709,"name":"Applied Linguistics","url":"https://www.academia.edu/Documents/in/Applied_Linguistics"},{"id":2524,"name":"Sociolinguistics","url":"https://www.academia.edu/Documents/in/Sociolinguistics"},{"id":892,"name":"Statistics","url":"https://www.academia.edu/Documents/in/Statistics"},{"id":3392,"name":"Critical Pedagogy","url":"https://www.academia.edu/Documents/in/Critical_Pedagogy"}]}</script><div class="work-card--no-attachment-details"><div style="font-weight: 700; font-size: 14px;">Abstract</div><div class="work-card--abstract js-swp-splash-abstract">Die Evolution von Rna-MolekuLen in vitro wird als Kletterprozes auf einer Fitness-Landschaft visualisiert, die aus molekularen Eigenschaften und Funktionen abgeleitet werden kann. Der Optimierungsprozes ist von einem hohen Redundanzgrad in den Abbildungen von den Polynukleotidsequenzen auf die MolekuLstrukturen GepraGt: Es gibt viel mehr Sequenzen als Strukturen und die Sequenzen, die in dieselbe Struktur falten, sind (beinahe) zufallig im Sequenzraum verteilt. Zwei Konsequenzen dieser Redundanz sind fur die Evolution wichtig: die GestaltraumuBerdeckung durch kleine verbundene Gebiete im Sequenzraum und die Existenz ausgedehnter neutraler Netzwerke. Beide Resultate erklaren zusammen, wie die Natur durch Versuch und Irrtum schnell und effizient Losungen fur komplexe Optimierungsprobleme finden kann, wahrend die Anzahl moglicher Genotypen jede Vorstellung ubersteigt. In Gegenwart neutraler Netzwerke vermeiden Populationen, in evolutionaren Fallen gefangen zu werden, und sie erreichen schlieslich das globale Optimum durch eine zusammengesetzte Dynamik von adaptiven Wanderungen und zufalliger Drift. Aus mathematischer Analyse abgeleitete Resultate werden mit den Resultaten von Computersimulationen und verfugbaren experimentellen Daten konfrontiert.</div></div><div class="request-upload--container"><p class="request-upload--title">Peter Schuster hasn't uploaded this paper.</p><div class="request-upload--info-text"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="info-circle" class="request-upload--info-icon svg-inline--fa fa-info-circle fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M256 8C119.043 8 8 119.083 8 256c0 136.997 111.043 248 248 248s248-111.003 248-248C504 119.083 392.957 8 256 8zm0 110c23.196 0 42 18.804 42 42s-18.804 42-42 42-42-18.804-42-42 18.804-42 42-42zm56 254c0 6.627-5.373 12-12 12h-88c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h12v-64h-12c-6.627 0-12-5.373-12-12v-24c0-6.627 5.373-12 12-12h64c6.627 0 12 5.373 12 12v100h12c6.627 0 12 5.373 12 12v24z"></path></svg><p class="no-margin hide-on-small-mobile">Let Peter know you want this paper to be uploaded.</p><p class="no-margin hide-above-small-mobile">Ask for this paper to be uploaded.</p></div><button class="work-cover--request-pdf-button small js-request-pdf-button hide-on-desktop"><svg style="width: 14px; 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