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its use in organ transplantation for wound healing and repairing. This article also explains uses of various stem cell types in transplantation technologies and its applications in regenerative medicine and therapeutics. This review also addresses tissue engineering methods and use of new biological scaffold materials and promising candidates such as immunomodulators, adhesions, integrins in tissue repairing and induction of regeneration in injured tissues. In addition, role of various molecules of immune cell system, gene cascades and transcription specific proteins (TSPs) and growth factors in formation of microenvironment for differentiation are also explained. Moreover, mechanism of regeneration in various tissues such as neural, skeletal, cardiac, muscular, adipose and gonadial tissues, and bone marrow is described in detail. This article also suggest an urgent need for development of new advanced methods, technologies, biomatrices, polymers and scaffold materials, and cell based therapies to overcome the problem of disable and injured patients. Hence, landmark innovations are required in the field of regenerative medicine, tissue engineering, and developmental biology for successful tissue repairing and organ transplants to serve the human society.","publication_date":"2015,,","publication_name":"journal of Regenerative Medicine and Tissue Engineering","grobid_abstract_attachment_id":"102420037"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Role of regeneration in tissue repairing and therapies","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [247877697]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script 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This field has made significant advances in recent years, particularly in the use of stem cells and biomaterials. Advancements in cell-based therapies have involved the use of cells to repair or replace damaged tissues and organs. Tissue engineering involves using scaffolds and growth factors to promote tissue regeneration. However, a major challenge in this field is the formation of adhesions, which can cause complications, such as intestinal obstruction and chronic pain. Adhesion barriers are used to prevent adhesion of tissues and organs during recovery, thereby reducing the risk of complications. Anti-adhesion materials, such as polysaccharides, proteins, and synthetic polymers, are used to create a physical barrier between tissues and prevent adhesion. 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Regenerative Medicine: Open Access, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Role of Biological Scaffolds, Hydro Gels and Stem Cells in Tissue Regeneration Therapy","attachmentId":101903192,"attachmentType":"pdf","work_url":"https://www.academia.edu/101332841/Role_of_Biological_Scaffolds_Hydro_Gels_and_Stem_Cells_in_Tissue_Regeneration_Therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/101332841/Role_of_Biological_Scaffolds_Hydro_Gels_and_Stem_Cells_in_Tissue_Regeneration_Therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="24735909" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/24735909/Review_Regenerative_Biology_and_Medicine_in_the_21_st_Century">Review: Regenerative Biology and Medicine in the 21 st Century</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="47578368" href="https://iu-indianapolis.academia.edu/DavidStocum">David Stocum</a></div><p class="ds-related-work--metadata ds2-5-body-xs">e-biomed: The Journal of Regenerative Medicine, 2000</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Review: Regenerative Biology and Medicine in the 21 st Century","attachmentId":45065411,"attachmentType":"pdf","work_url":"https://www.academia.edu/24735909/Review_Regenerative_Biology_and_Medicine_in_the_21_st_Century","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/24735909/Review_Regenerative_Biology_and_Medicine_in_the_21_st_Century"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="68583690" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine">Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38366464" href="https://uct.academia.edu/KevinDzobo">Kevin Dzobo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Stem cells international, 2018</p><p class="ds-related-work--abstract ds2-5-body-sm">Humans and animals lose tissues and organs due to congenital defects, trauma, and diseases. 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