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(PDF) Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine

<!DOCTYPE html> <html > <head> <meta charset="utf-8"> <meta rel="search" type="application/opensearchdescription+xml" href="/open_search.xml" title="Academia.edu"> <meta content="width=device-width, initial-scale=1" name="viewport"> <meta name="google-site-verification" content="bKJMBZA7E43xhDOopFZkssMMkBRjvYERV-NaN4R6mrs"> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="wJcpOK7ybP2mQQnMi7kRuRi2A2_kXcNmNUeT2zYRt6QB7EKAaJ9BUwNFN-hMgv9w4UdDCiyh2bknvth1wXIKPg" /> <meta name="citation_title" content="Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine" /> <meta name="citation_publication_date" content="2018" /> <meta name="citation_journal_title" content="Stem Cells International" /> <meta name="citation_author" content="Kevin Dzobo" /> <meta name="citation_author" content="Nicholas Ekow Thomford" /> <meta name="citation_author" content="Dimakatso Alice Senthebane" /> <meta name="citation_author" content="Hendrina Shipanga" /> <meta name="citation_author" content="Arielle Rowe" /> <meta name="citation_author" content="Collet Dandara" /> <meta name="citation_author" content="Michael Pillay" /> <meta name="citation_author" content="Keolebogile Shirley Caroline M. Motaung" /> <meta name="citation_volume" content="2018" /> <meta name="citation_firstpage" content="1-24" /> <meta name="citation_issn" content="1687-966X" /> <meta name="twitter:card" content="summary" /> <meta name="twitter:url" content="https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine" /> <meta name="twitter:title" content="Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine" /> <meta name="twitter:description" content="Humans and animals lose tissues and organs due to congenital defects, trauma, and diseases. The human body has a low regenerative potential as opposed to the urodele amphibians commonly referred to as salamanders. Globally, millions of people would" /> <meta name="twitter:image" content="https://0.academia-photos.com/38366464/13702797/14830731/s200_kevin.dzobo.jpg" /> <meta property="fb:app_id" content="2369844204" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine" /> <meta property="og:title" content="Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine" /> <meta property="og:image" content="http://a.academia-assets.com/images/open-graph-icons/fb-paper.gif" /> <meta property="og:description" content="Humans and animals lose tissues and organs due to congenital defects, trauma, and diseases. The human body has a low regenerative potential as opposed to the urodele amphibians commonly referred to as salamanders. Globally, millions of people would" /> <meta property="article:author" content="https://uct.academia.edu/KevinDzobo" /> <meta name="description" content="Humans and animals lose tissues and organs due to congenital defects, trauma, and diseases. The human body has a low regenerative potential as opposed to the urodele amphibians commonly referred to as salamanders. Globally, millions of people would" /> <title>(PDF) Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine</title> <link rel="canonical" href="https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = 'b092bf3a3df71cf13feee7c143e83a57eb6b94fb'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1739815537000); window.Aedu.timeDifference = new Date().getTime() - 1739815537000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Humans and animals lose tissues and organs due to congenital defects, trauma, and diseases. The human body has a low regenerative potential as opposed to the urodele amphibians commonly referred to as salamanders. Globally, millions of people would benefit immensely if tissues and organs can be replaced on demand. Traditionally, transplantation of intact tissues and organs has been the bedrock to replace damaged and diseased parts of the body. The sole reliance on transplantation has created a waiting list of people requiring donated tissues and organs, and generally, supply cannot meet the demand. The total cost to society in terms of caring for patients with failing organs and debilitating diseases is enormous. Scientists and clinicians, motivated by the need to develop safe and reliable sources of tissues and organs, have been improving therapies and technologies that can regenerate tissues and in some cases create new tissues altogether. Tissue engineering and/or regenerative me...","author":[{"@context":"https://schema.org","@type":"Person","name":"Kevin Dzobo","url":"https://uct.academia.edu/KevinDzobo"}],"contributor":[],"dateCreated":"2022-01-17","dateModified":"2022-01-18","datePublished":"2018-01-01","headline":"Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine","image":"https://attachments.academia-assets.com/79011211/thumbnails/1.jpg","inLanguage":"en","keywords":["Engineering","Stem Cells","Medicine"],"publication":"Stem cells international","publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":"uct"}],"thumbnailUrl":"https://attachments.academia-assets.com/79011211/thumbnails/1.jpg","url":"https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine"}</script><style 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The human body has a low regenerative potential as opposed to the urodele amphibians commonly referred to as salamanders. Globally, millions of people would benefit immensely if tissues and organs can be replaced on demand. Traditionally, transplantation of intact tissues and organs has been the bedrock to replace damaged and diseased parts of the body. The sole reliance on transplantation has created a waiting list of people requiring donated tissues and organs, and generally, supply cannot meet the demand. The total cost to society in terms of caring for patients with failing organs and debilitating diseases is enormous. Scientists and clinicians, motivated by the need to develop safe and reliable sources of tissues and organs, have been improving therapies and technologies that can regenerate tissues and in some cases create new tissues altogether. Tissue engineering and/or regenerative me...","publication_date":"2018,,","publication_name":"Stem cells international"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [38366464]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loginModal = {}; window.loginModal.appleClientId = 'edu.academia.applesignon'; window.userInChina = "false";</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card ds-work-card--no-bottom-spacing"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;swp-splash-paper-cover&quot;,&quot;attachmentId&quot;:79011211,&quot;attachmentType&quot;:&quot;pdf&quot;}"><img alt="First page of “Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/79011211/mini_magick20220117-5012-1fpkce3.png?1642492613" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/images/single_work_splash/adobe_icon.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="38366464" href="https://uct.academia.edu/KevinDzobo"><img alt="Profile image of Kevin Dzobo" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/38366464/13702797/14830731/s65_kevin.dzobo.jpg" />Kevin Dzobo</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2018, Stem cells international</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">25 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 68583690; 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if (!viewCountBody) { throw new Error('Failed to find work views element'); } viewCountBody.textContent = `${commaizedViewCount} views`; } catch (error) { // Remove the whole views element if there was some issue parsing. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); throw new Error(`Failed to parse view count: ${viewCount}`, error); } }; // If the DOM is still loading, wait for it to be ready before updating the view count. if (document.readyState === "loading") { document.addEventListener('DOMContentLoaded', () => { updateViewCount(viewCount); }); // Otherwise, just update it immediately. } else { updateViewCount(viewCount); } })();</script></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Humans and animals lose tissues and organs due to congenital defects, trauma, and diseases. The human body has a low regenerative potential as opposed to the urodele amphibians commonly referred to as salamanders. Globally, millions of people would benefit immensely if tissues and organs can be replaced on demand. Traditionally, transplantation of intact tissues and organs has been the bedrock to replace damaged and diseased parts of the body. The sole reliance on transplantation has created a waiting list of people requiring donated tissues and organs, and generally, supply cannot meet the demand. The total cost to society in terms of caring for patients with failing organs and debilitating diseases is enormous. Scientists and clinicians, motivated by the need to develop safe and reliable sources of tissues and organs, have been improving therapies and technologies that can regenerate tissues and in some cases create new tissues altogether. 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