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(PDF) Evaluation of booster doses of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine in 18-month-old children | John Thipphawong - Academia.edu

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"https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F31495252%2FEvaluation_of_booster_doses_of_Haemophilus_influenzae_type_b_tetanus_toxoid_conjugate_vaccine_in_18_month_old_children%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":51844395,"identifier":"Attachment_51844395","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":31495252,"created_at":"2017-02-17T18:53:44.717-08:00","from_world_paper_id":160943185,"updated_at":"2024-11-18T00:53:40.653-08:00","_data":{"grobid_abstract":"). Systemic adverse events did not differ in type or frequency betwen groups. Before immunization, the geometric mean anti-PRP level in those tested was 0.41 I~g ml-1; 26.7% had levels below 0.15 #g ml-1. Both treatment groups responded strongly to vaccination. In those serially tested, anti-PRP levels rose by over 90-fold, to 38.1 #9 ml-1. No difference existed between postimmunization anti-PRP levels in those given PRP-T separately or mixed with DPT. No intergroup differences existed for postimmunization levels of diphtheria, tetanus or pertussis antibodies tested. We conclude that booster doses of PRP-T are safe and highly immunogenic even when mixed in one syringe with DPT vaccine.","publication_date":"1995,,","publication_name":"Vaccine","grobid_abstract_attachment_id":"51844395"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Evaluation of booster doses of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine in 18-month-old children","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [60261763]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div 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class="ds-related-work--metadata ds2-5-body-xs">2003</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Safety and immunogenicity of a diphtheria, tetanus, and acellular pertussis-inactivated poliovirus vaccine/Haemophilus influenzae type B combination vaccine administered to Taiwanese infants at 2, 4, and 6 months of age&quot;,&quot;attachmentId&quot;:44589504,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/14115018/Safety_and_immunogenicity_of_a_diphtheria_tetanus_and_acellular_pertussis_inactivated_poliovirus_vaccine_Haemophilus_influenzae_type_B_combination_vaccine_administered_to_Taiwanese_infants_at_2_4_and_6_months_of_age&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/14115018/Safety_and_immunogenicity_of_a_diphtheria_tetanus_and_acellular_pertussis_inactivated_poliovirus_vaccine_Haemophilus_influenzae_type_B_combination_vaccine_administered_to_Taiwanese_infants_at_2_4_and_6_months_of_age"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="11705278" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/11705278/Adverse_effects_and_sero_responses_to_an_acellular_pertussis_diphtheria_tetanus_vaccine_when_combined_with_Haemophilus_influenzae_type_b_vaccine_in_an_">Adverse effects and sero-responses to an acellular pertussis/diphtheria/tetanus vaccine when combined with Haemophilus influenzae type b vaccine in an …</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="28678171" href="https://independent.academia.edu/JennyMaclennan">Jenny Maclennan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European journal of …, 1999</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Adverse effects and sero-responses to an acellular pertussis/diphtheria/tetanus vaccine when combined with Haemophilus influenzae type b vaccine in an …&quot;,&quot;attachmentId&quot;:46566380,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/11705278/Adverse_effects_and_sero_responses_to_an_acellular_pertussis_diphtheria_tetanus_vaccine_when_combined_with_Haemophilus_influenzae_type_b_vaccine_in_an_&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/11705278/Adverse_effects_and_sero_responses_to_an_acellular_pertussis_diphtheria_tetanus_vaccine_when_combined_with_Haemophilus_influenzae_type_b_vaccine_in_an_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="14115044" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/14115044/A_fully_liquid_diphtheria_tetanus_five_component_acellular_pertussis_inactivated_poliomyelitis_Haemophilus_influenzae_type_b_conjugate_vaccine_immunogenicity_and_safety_of_primary_vaccination_in_Taiwanese_infants">A fully liquid diphtheria–tetanus–five component acellular pertussis–inactivated poliomyelitis–Haemophilus influenzae type b conjugate vaccine: immunogenicity and safety of primary vaccination in Taiwanese infants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33115704" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Infectious Diseases, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;A fully liquid diphtheria–tetanus–five component acellular pertussis–inactivated poliomyelitis–Haemophilus influenzae type b conjugate vaccine: immunogenicity and safety of primary vaccination in Taiwanese infants&quot;,&quot;attachmentId&quot;:44589502,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/14115044/A_fully_liquid_diphtheria_tetanus_five_component_acellular_pertussis_inactivated_poliomyelitis_Haemophilus_influenzae_type_b_conjugate_vaccine_immunogenicity_and_safety_of_primary_vaccination_in_Taiwanese_infants&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/14115044/A_fully_liquid_diphtheria_tetanus_five_component_acellular_pertussis_inactivated_poliomyelitis_Haemophilus_influenzae_type_b_conjugate_vaccine_immunogenicity_and_safety_of_primary_vaccination_in_Taiwanese_infants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="18549004" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/18549004/Safety_and_immunogenicity_of_a_combined_five_component_pertussis_diphtheria_tetanus_inactivated_poliomyelitis_Haemophilus_b_conjugate_vaccine_administered_to_infants_at_two_four_and_six_months_of_age">Safety and immunogenicity of a combined five-component pertussis-diphtheria-tetanus-inactivated poliomyelitis-Haemophilus b conjugate vaccine administered to infants at two, four and six months of age</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="60261763" href="https://independent.academia.edu/JohnThipphawong">John Thipphawong</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38584614" href="https://nrc-ca.academia.edu/LuisBarreto">Luis Barreto</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1998</p><p class="ds-related-work--abstract ds2-5-body-sm">Safety, immunogenicity and lot consistency of five-component pertussis combination vaccine (CPDT-IPV//PRP-T) in infants were compared to that of whole cell pertussis combination vaccine (DPT-IPV//PRP-T), as were separate and combined injections of CPDT-IPV and PRP-T. No significant differences in adverse event rates were observed between lots of CPDT-IPV//PRP-T or between separate or combined injections of CPDT-IPV and PRP-T. Minor differences in antibody responses were observed between lots of component pertussis vaccine. Higher concentrations of diphtheria and tetanus antitoxins were induced by separate than by combined injection of CPDT-IPV and PRP-T, but no other differences in immunogenicity were observed. Adverse reactions were more than twice as frequent after whole cell than after component pertussis vaccines. Antibody responses to pertussis toxoid, filamentous hemagglutin and pertactin were significantly greater after component vaccines, while the response to type 3 poliovirus was higher after whole cell vaccine. No significant differences were observed for other vaccine components. CPDT-IPV//PRP-T was safe and immunogenic in infants. Antibody results were similar to those observed in a Swedish field trial that demonstrated CPDT to be 85% effective in preventing clinical pertussis.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Safety and immunogenicity of a combined five-component pertussis-diphtheria-tetanus-inactivated poliomyelitis-Haemophilus b conjugate vaccine administered to infants at two, four and six months of age&quot;,&quot;attachmentId&quot;:42159872,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/18549004/Safety_and_immunogenicity_of_a_combined_five_component_pertussis_diphtheria_tetanus_inactivated_poliomyelitis_Haemophilus_b_conjugate_vaccine_administered_to_infants_at_two_four_and_six_months_of_age&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/18549004/Safety_and_immunogenicity_of_a_combined_five_component_pertussis_diphtheria_tetanus_inactivated_poliomyelitis_Haemophilus_b_conjugate_vaccine_administered_to_infants_at_two_four_and_six_months_of_age"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="78726400" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/78726400/Primary_vaccination_of_infants_with_diphtheria_tetanus_acellular_pertussis_hepatitis_B_virus_inactivated_polio_virus_and_Haemophilus_influenzae_type_b_vaccines_given_as_either_separate_or_mixed_injections">Primary vaccination of infants with diphtheria-tetanus-acellular pertussis–hepatitis B virus– inactivated polio virus and Haemophilus influenzae type b vaccines given as either separate or mixed injections</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="55520528" href="https://independent.academia.edu/SchmittHeinz">Heinz Schmitt</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Journal of Pediatrics, 2000</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Primary vaccination of infants with diphtheria-tetanus-acellular pertussis–hepatitis B virus– inactivated polio virus and Haemophilus influenzae type b vaccines given as either separate or mixed injections&quot;,&quot;attachmentId&quot;:85672092,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/78726400/Primary_vaccination_of_infants_with_diphtheria_tetanus_acellular_pertussis_hepatitis_B_virus_inactivated_polio_virus_and_Haemophilus_influenzae_type_b_vaccines_given_as_either_separate_or_mixed_injections&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/78726400/Primary_vaccination_of_infants_with_diphtheria_tetanus_acellular_pertussis_hepatitis_B_virus_inactivated_polio_virus_and_Haemophilus_influenzae_type_b_vaccines_given_as_either_separate_or_mixed_injections"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:51844395,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" 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You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="15658011" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/15658011/Adverse_effects_and_sero_responses_to_an_acellular_pertussis_diphtheria_tetanus_vaccine_when_combined_with_Haemophilus_influenzae_type_b_vaccine_in_an_accelerated_schedule">Adverse effects and sero-responses to an acellular pertussis/diphtheria/tetanus vaccine when combined with Haemophilus influenzae type b vaccine in an accelerated schedule</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" 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href="https://www.academia.edu/11705277/Effect_of_combination_with_an_acellular_pertussis_diphtheria_tetanus_vaccine_on_antibody_response_to_Hib_vaccine_PRP_T_">Effect of combination with an acellular pertussis, diphtheria, tetanus vaccine on antibody response to Hib vaccine (PRP-T)</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="28678171" href="https://independent.academia.edu/JennyMaclennan">Jenny Maclennan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1998</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Effect of combination with an acellular pertussis, diphtheria, tetanus vaccine on antibody response to Hib vaccine 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data-entity-id="24222128" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/24222128/The_use_of_Haemophilus_influenzae_type_b_tetanus_toxoid_conjugate_vaccine_mixed_with_diphtheria_tetanus_pertussis_vaccine_in_Gambian_infants">The use of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine mixed with diphtheria-tetanus-pertussis vaccine in Gambian infants</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="46629081" href="https://independent.academia.edu/JoelWard6">Joel Ward</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1996</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;The use of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine mixed with diphtheria-tetanus-pertussis vaccine in Gambian infants&quot;,&quot;attachmentId&quot;:44552389,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/24222128/The_use_of_Haemophilus_influenzae_type_b_tetanus_toxoid_conjugate_vaccine_mixed_with_diphtheria_tetanus_pertussis_vaccine_in_Gambian_infants&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/24222128/The_use_of_Haemophilus_influenzae_type_b_tetanus_toxoid_conjugate_vaccine_mixed_with_diphtheria_tetanus_pertussis_vaccine_in_Gambian_infants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="3" data-entity-id="26688399" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26688399/Immunogenicity_and_reactogenicity_of_two_diphtheria_tetanus_acellular_pertussis_hepatitis_B_inactivated_polio_virus_Haemophilus_influenzae_type_b_vaccines_administered_at_3_5_and_11_12_months_of_age">Immunogenicity and reactogenicity of two diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated polio virus- Haemophilus influenzae type b vaccines administered at 3, 5 and 11–12 months of age</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50682354" href="https://independent.academia.edu/MahmoodJedditehrani">Mahmood Jeddi-tehrani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Human Vaccines, 2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Immunogenicity and reactogenicity of two diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated polio virus- Haemophilus influenzae type b vaccines administered at 3, 5 and 11–12 months of age&quot;,&quot;attachmentId&quot;:46970339,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/26688399/Immunogenicity_and_reactogenicity_of_two_diphtheria_tetanus_acellular_pertussis_hepatitis_B_inactivated_polio_virus_Haemophilus_influenzae_type_b_vaccines_administered_at_3_5_and_11_12_months_of_age&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span 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href="https://www.academia.edu/4578781/Pattern_of_functional_antibody_activity_against_Haemophilus_influenzae_type_b_Hib_in_infants_immunized_with_diphtheria_tetanus_pertussis_Hib_Brazilian_combination_vaccine">Pattern of functional antibody activity against Haemophilus influenzae type b (Hib) in infants immunized with diphtheria-tetanus-pertussis/Hib Brazilian combination vaccine</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="5742284" href="https://independent.academia.edu/ReinaldodeMenezesMartins">Reinaldo de Menezes Martins</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Brazilian Journal of Medical and Biological Research, 2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Pattern of functional antibody 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class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="5" data-entity-id="25080311" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/25080311/Assessment_of_nine_candidate_DTP_vaccines_with_reduced_amount_of_antigen_and_or_without_adjuvant_as_a_fourth_booster_dose_in_the_second_year_of_life">Assessment of nine candidate DTP-vaccines with reduced amount of antigen and/or without adjuvant as a fourth (booster-) dose in the second year of life</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="48238879" href="https://independent.academia.edu/ClemensRalf">Ralf Clemens</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Assessment of nine candidate DTP-vaccines with reduced amount of antigen and/or without adjuvant as a fourth (booster-) dose in the second year of life&quot;,&quot;attachmentId&quot;:45402377,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/25080311/Assessment_of_nine_candidate_DTP_vaccines_with_reduced_amount_of_antigen_and_or_without_adjuvant_as_a_fourth_booster_dose_in_the_second_year_of_life&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/25080311/Assessment_of_nine_candidate_DTP_vaccines_with_reduced_amount_of_antigen_and_or_without_adjuvant_as_a_fourth_booster_dose_in_the_second_year_of_life"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="6" data-entity-id="18549010" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/18549010/Safety_and_immunogenicity_of_an_acellular_pertussis_diphtheria_tetanus_vaccine_given_as_a_single_injection_with_Haemophilus_influenzae_b_conjugate_vaccine">Safety and immunogenicity of an acellular pertussis diphtheria tetanus vaccine given as a single injection with Haemophilus influenzae b conjugate vaccine</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38584614" href="https://nrc-ca.academia.edu/LuisBarreto">Luis Barreto</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1997</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Safety and immunogenicity of an acellular pertussis diphtheria tetanus vaccine given as a single injection with Haemophilus influenzae b conjugate vaccine&quot;,&quot;attachmentId&quot;:42159871,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/18549010/Safety_and_immunogenicity_of_an_acellular_pertussis_diphtheria_tetanus_vaccine_given_as_a_single_injection_with_Haemophilus_influenzae_b_conjugate_vaccine&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/18549010/Safety_and_immunogenicity_of_an_acellular_pertussis_diphtheria_tetanus_vaccine_given_as_a_single_injection_with_Haemophilus_influenzae_b_conjugate_vaccine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="7" data-entity-id="96424509" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/96424509/Reactogenicity_and_immunogenicity_of_reduced_antigen_content_diphtheria_tetanus_acellular_pertussis_vaccines_as_a_booster_in_4_7_year_old_children_primed_with_diphtheria_tetanus_whole_cell_pertussis_vaccine_before_2_years_of_age">Reactogenicity and immunogenicity of reduced antigen content diphtheria–tetanus–acellular pertussis vaccines as a booster in 4–7-year-old children primed with diphtheria–tetanus–whole cell pertussis vaccine before 2 years of age</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="116297980" href="https://independent.academia.edu/KarimIgbaria">Karim Igbaria</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1999</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Reactogenicity and immunogenicity of reduced antigen content diphtheria–tetanus–acellular pertussis vaccines as a booster in 4–7-year-old children primed with diphtheria–tetanus–whole cell pertussis vaccine before 2 years of age&quot;,&quot;attachmentId&quot;:98326295,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/96424509/Reactogenicity_and_immunogenicity_of_reduced_antigen_content_diphtheria_tetanus_acellular_pertussis_vaccines_as_a_booster_in_4_7_year_old_children_primed_with_diphtheria_tetanus_whole_cell_pertussis_vaccine_before_2_years_of_age&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/96424509/Reactogenicity_and_immunogenicity_of_reduced_antigen_content_diphtheria_tetanus_acellular_pertussis_vaccines_as_a_booster_in_4_7_year_old_children_primed_with_diphtheria_tetanus_whole_cell_pertussis_vaccine_before_2_years_of_age"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="8" data-entity-id="16795806" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/16795806/Reactogenicity_and_Safety_of_DTPa_Vaccine_and_Haemophilus_influenzae_Type_b_Conjugate_Vaccine_Hib_in_a_Single_Injection_vs_DTPw_and_Hib_as_Separate_Injections_as_a_Booster_Vaccination_in_18_Month_Old_Children">Reactogenicity and Safety of DTPa Vaccine and Haemophilus influenzae Type b Conjugate Vaccine (Hib) in a Single Injection vs DTPw and Hib as Separate Injections as a Booster Vaccination in 18-Month-Old Children</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36236693" href="https://independent.academia.edu/JosepMar%C3%A9s">Josep Marés</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Drug Investigation, 2001</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Reactogenicity and Safety of DTPa Vaccine and Haemophilus influenzae Type b Conjugate Vaccine (Hib) in a Single Injection vs DTPw and Hib as Separate Injections as a Booster Vaccination in 18-Month-Old Children&quot;,&quot;attachmentId&quot;:39187355,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/16795806/Reactogenicity_and_Safety_of_DTPa_Vaccine_and_Haemophilus_influenzae_Type_b_Conjugate_Vaccine_Hib_in_a_Single_Injection_vs_DTPw_and_Hib_as_Separate_Injections_as_a_Booster_Vaccination_in_18_Month_Old_Children&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/16795806/Reactogenicity_and_Safety_of_DTPa_Vaccine_and_Haemophilus_influenzae_Type_b_Conjugate_Vaccine_Hib_in_a_Single_Injection_vs_DTPw_and_Hib_as_Separate_Injections_as_a_Booster_Vaccination_in_18_Month_Old_Children"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="9" data-entity-id="2495889" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/2495889/Immunogenicity_study_of_a_combined_diphtheria_tetanus_acellular_pertussis_inactivated_poliomyelitis_vaccine_used_to_reconstitute_a_freeze_dried_Haemophilus_influenzae_type_b_vaccine_DTaP_IPV_PRP_T_administered_simultaneously_with_a_hepatitis_B_vaccine_at_two_three_and_four_months_of_life">Immunogenicity study of a combined diphtheria, tetanus, acellular pertussis, inactivated poliomyelitis vaccine used to reconstitute a freeze-dried Haemophilus influenzae type b vaccine (DTaP-IPV//PRP-T) administered simultaneously with a hepatitis B vaccine at two, three and four months of life</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="2293675" href="https://ankara.academia.edu/BetulUlukol">Betul Ulukol</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1999</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Immunogenicity study of a combined diphtheria, tetanus, acellular pertussis, inactivated poliomyelitis vaccine used to reconstitute a freeze-dried Haemophilus influenzae type b vaccine (DTaP-IPV//PRP-T) administered simultaneously with a hepatitis B vaccine at two, three and four months of life&quot;,&quot;attachmentId&quot;:50600022,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/2495889/Immunogenicity_study_of_a_combined_diphtheria_tetanus_acellular_pertussis_inactivated_poliomyelitis_vaccine_used_to_reconstitute_a_freeze_dried_Haemophilus_influenzae_type_b_vaccine_DTaP_IPV_PRP_T_administered_simultaneously_with_a_hepatitis_B_vaccine_at_two_three_and_four_months_of_life&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/2495889/Immunogenicity_study_of_a_combined_diphtheria_tetanus_acellular_pertussis_inactivated_poliomyelitis_vaccine_used_to_reconstitute_a_freeze_dried_Haemophilus_influenzae_type_b_vaccine_DTaP_IPV_PRP_T_administered_simultaneously_with_a_hepatitis_B_vaccine_at_two_three_and_four_months_of_life"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="10" data-entity-id="92826712" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/92826712/Reactogenicity_and_Immunogenicity_Profiles_of_a_Novel_Pentavalent_Diphtheria_Tetanus_Whole_Cell_Pertussis_Hepatitis_B_and_Haemophilus_Influenzae_Type_B_Vaccine">Reactogenicity and Immunogenicity Profiles of a Novel Pentavalent Diphtheria-Tetanus???Whole Cell Pertussis???Hepatitis B and Haemophilus Influenzae Type B Vaccine</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="249836346" href="https://independent.academia.edu/TheinAungMyat">Aung Myat Thein</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Pediatric Infectious Disease Journal, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Reactogenicity and Immunogenicity Profiles of a Novel Pentavalent Diphtheria-Tetanus???Whole Cell Pertussis???Hepatitis B and Haemophilus Influenzae Type B Vaccine&quot;,&quot;attachmentId&quot;:95732621,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/92826712/Reactogenicity_and_Immunogenicity_Profiles_of_a_Novel_Pentavalent_Diphtheria_Tetanus_Whole_Cell_Pertussis_Hepatitis_B_and_Haemophilus_Influenzae_Type_B_Vaccine&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/92826712/Reactogenicity_and_Immunogenicity_Profiles_of_a_Novel_Pentavalent_Diphtheria_Tetanus_Whole_Cell_Pertussis_Hepatitis_B_and_Haemophilus_Influenzae_Type_B_Vaccine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="11" data-entity-id="9070602" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/9070602/Reactogenicity_and_immunogenicity_of_reduced_antigen_content_diphtheria_tetanus_acellular_pertussis_vaccine_dTpa_administered_as_a_booster_to_4_6_year_old_children_primed_with_four_doses_of_whole_cell_pertussis_vaccine">Reactogenicity and immunogenicity of reduced antigen content diphtheria–tetanus–acellular pertussis vaccine (dTpa) administered as a booster to 4–6 year-old children primed with four doses of whole-cell pertussis vaccine</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="20575384" href="https://unrika.academia.edu/HansHutagalung">Hans Hutagalung</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 2003</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Reactogenicity and immunogenicity of reduced antigen content diphtheria–tetanus–acellular pertussis vaccine (dTpa) administered as a booster to 4–6 year-old children primed with four doses of whole-cell pertussis vaccine&quot;,&quot;attachmentId&quot;:47897225,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/9070602/Reactogenicity_and_immunogenicity_of_reduced_antigen_content_diphtheria_tetanus_acellular_pertussis_vaccine_dTpa_administered_as_a_booster_to_4_6_year_old_children_primed_with_four_doses_of_whole_cell_pertussis_vaccine&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" 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href="https://www.academia.edu/63313923/Safety_and_immunogenicity_of_combined_diphtheria_tetanus_pertussis_whole_cell_and_acellular_Haemophilus_influenzae_b_conjugate_vaccines_administered_to_">Safety and immunogenicity of combined diphtheria-tetanus-pertussis (whole cell and acellular)-Haemophilus influenzae-b conjugate vaccines administered to …</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33366343" href="https://independent.academia.edu/NarainPunjabi">Narain Punjabi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1999</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Safety and immunogenicity of combined diphtheria-tetanus-pertussis (whole cell and acellular)-Haemophilus influenzae-b conjugate 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href="https://independent.academia.edu/ChatterjeeSukanta">Sukanta Chatterjee</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="47576509" href="https://independent.academia.edu/BaldevBhatia">Baldev Bhatia</a></div><p class="ds-related-work--metadata ds2-5-body-xs">BMC Infectious Diseases, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;The immunogenicity and safety of a reduced PRP-content DTPw-HBV/Hib vaccine when administered according to the accelerated EPI 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href="https://independent.academia.edu/EugeniodeFrutos">Eugenio de Frutos</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36236693" href="https://independent.academia.edu/JosepMar%C3%A9s">Josep Marés</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 2003</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Comparison of the reactogenicity and immunogenicity of a combined diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated polio (DTPa–HBV–IPV) vaccine, mixed with the Haemophilus influenzae type b (Hib) conjugate vaccine and administered as a single injection, with the DTPa–IPV/Hib 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href="https://www.academia.edu/16795810/Comparison_of_the_reactogenicity_and_immunogenicity_of_a_combined_diphtheria_tetanus_acellular_pertussis_hepatitis_B_inactivated_polio_DTPa_HBV_IPV_vaccine_mixed_with_the_Haemophilus_influenzae_type_b_Hib_conjugate_vaccine_and_administered_as_a_single_injection_with_the_DTPa_IPV_Hib_and_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="17" data-entity-id="25080284" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/25080284/Reactogenicity_and_immunogenicity_of_a_booster_dose_of_a_combined_diphtheria_tetanus_and_tricomponent_acellular_pertussis_vaccine_at_fourteen_to_twenty_eight_months_of_age">Reactogenicity and immunogenicity of a 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translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="18" data-entity-id="97901018" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/97901018/One_year_post_primary_antibody_persistence_and_booster_immune_response_to_a_fully_liquid_five_component_acellular_pertussis_diphtheria_tetanus_inactivated_poliomyelitis_Haemophilus_influenzae_type_b_conjugate_vaccine">One-year post-primary antibody persistence and booster immune response to a fully liquid five-component acellular pertussis, diphtheria, tetanus, inactivated poliomyelitis, Haemophilus influenzae type b conjugate vaccine</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37125941" href="https://independent.academia.edu/desmonsiregar">desmon siregar</a></div><p 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