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A better understanding of the pathogenesis of this disease may help with prevention and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_49659927" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">BackgroundThe environment preferred by Acanthamoeba trophozoites and the mechanism by which the amebae enters the cornea are not yet fully understood. A better understanding of the pathogenesis of this disease may help with prevention and treatment.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/49659927" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5a4e62807c6f5be753e5c4b0911d3214" rel="nofollow" data-download="{"attachment_id":67951904,"asset_id":49659927,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67951904/download_file?st=MTczMjQ3NzUwMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="57822852" href="https://independent.academia.edu/JanBergmanson">Jan Bergmanson</a><script data-card-contents-for-user="57822852" type="text/json">{"id":57822852,"first_name":"Jan","last_name":"Bergmanson","domain_name":"independent","page_name":"JanBergmanson","display_name":"Jan Bergmanson","profile_url":"https://independent.academia.edu/JanBergmanson?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_49659927 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="49659927"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 49659927, container: ".js-paper-rank-work_49659927", }); });</script></li><li class="js-percentile-work_49659927 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 49659927; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_49659927"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_49659927 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="49659927"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 49659927; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=49659927]").text(description); $(".js-view-count-work_49659927").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_49659927").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="49659927"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a>, <script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="359001" href="https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology">Optometry and Ophthalmology</a>, <script data-card-contents-for-ri="359001" type="text/json">{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="591104" href="https://www.academia.edu/Documents/in/Chlorine">Chlorine</a><script data-card-contents-for-ri="591104" type="text/json">{"id":591104,"name":"Chlorine","url":"https://www.academia.edu/Documents/in/Chlorine?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=49659927]'), work: {"id":49659927,"title":"In vitro effects of medium tonicity, nutrient concentration, and free chlorine content on Acanthamoeba","created_at":"2021-07-09T10:48:34.760-07:00","url":"https://www.academia.edu/49659927/In_vitro_effects_of_medium_tonicity_nutrient_concentration_and_free_chlorine_content_on_Acanthamoeba?f_ri=17721","dom_id":"work_49659927","summary":"BackgroundThe environment preferred by Acanthamoeba trophozoites and the mechanism by which the amebae enters the cornea are not yet fully understood. A better understanding of the pathogenesis of this disease may help with prevention and treatment.","downloadable_attachments":[{"id":67951904,"asset_id":49659927,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":57822852,"first_name":"Jan","last_name":"Bergmanson","domain_name":"independent","page_name":"JanBergmanson","display_name":"Jan Bergmanson","profile_url":"https://independent.academia.edu/JanBergmanson?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721","nofollow":false},{"id":591104,"name":"Chlorine","url":"https://www.academia.edu/Documents/in/Chlorine?f_ri=17721","nofollow":false},{"id":909335,"name":"Acanthamoeba","url":"https://www.academia.edu/Documents/in/Acanthamoeba?f_ri=17721"},{"id":957359,"name":"Culture Media","url":"https://www.academia.edu/Documents/in/Culture_Media?f_ri=17721"},{"id":1157148,"name":"Cell Survival","url":"https://www.academia.edu/Documents/in/Cell_Survival?f_ri=17721"},{"id":2516464,"name":"Nutrient Concentration","url":"https://www.academia.edu/Documents/in/Nutrient_Concentration?f_ri=17721"},{"id":3975139,"name":"Tonicity","url":"https://www.academia.edu/Documents/in/Tonicity?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_26703595 coauthored" data-work_id="26703595" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/26703595/An_adaptive_algorithm_for_the_cornea_modeling_from_keratometric_data">An adaptive algorithm for the cornea modeling from keratometric data</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In this paper we describe an adaptive and multi-scale algorithm for the parsimonious fit of the corneal surface data that allows to adapt the number of functions used in the reconstruction to the conditions of each cornea. The method... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_26703595" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In this paper we describe an adaptive and multi-scale algorithm for the parsimonious fit of the corneal surface data that allows to adapt the number of functions used in the reconstruction to the conditions of each cornea. The method implements also a dynamical selection of the parameters and the management of noise. It can be used for the real-time reconstruction</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/26703595" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c94fc52349ccf219fdc17dd53075966b" rel="nofollow" data-download="{"attachment_id":46985304,"asset_id":26703595,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46985304/download_file?st=MTczMjQ3NzUwMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37828835" href="https://ual-es.academia.edu/dramoslopez">Darío Ramos-López</a><script data-card-contents-for-user="37828835" type="text/json">{"id":37828835,"first_name":"Darío","last_name":"Ramos-López","domain_name":"ual-es","page_name":"dramoslopez","display_name":"Darío Ramos-López","profile_url":"https://ual-es.academia.edu/dramoslopez?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-26703595">+2</span><div class="hidden js-additional-users-26703595"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://ual-es.academia.edu/AndreiMartinezFinkelshtein">Andrei Martinez Finkelshtein</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/JorgeAlio">Jorge Alio</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-26703595'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-26703595').html(); 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class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_64425422" data-work_id="64425422" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/64425422/UV_Rays_the_prooxidant_antioxidant_imbalance_in_the_cornea_and_oxidative_eye_damage">UV Rays, the prooxidant/antioxidant imbalance in the cornea and oxidative eye damage</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In this minireview, the factors involved in the development of corneal injury due to an increased amount of UVB rays are summarized. Experimental studies have shown that an increased number of UVB rays leads to a profound decrease in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_64425422" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In this minireview, the factors involved in the development of corneal injury due to an increased amount of UVB rays are summarized. Experimental studies have shown that an increased number of UVB rays leads to a profound decrease in corneal antioxidants (high molecular weight, antioxidant enzymes as well as low molecular weight, mainly ascorbic acid) so that a prooxidant/antioxidant imbalance appears. The decrease of corneal antioxidant protective mechanisms results in oxidative injury of the cornea and causes damage of the inner parts of the eye by UVB rays and by reactive oxygen species generated by them.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/64425422" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="52825cafc1d22ac7cd03ec1a0cd767c2" rel="nofollow" data-download="{"attachment_id":76469526,"asset_id":64425422,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/76469526/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32385248" href="https://independent.academia.edu/AMidelfart">A. 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Experimental studies have shown that an increased number of UVB rays leads to a profound decrease in corneal antioxidants (high molecular weight, antioxidant enzymes as well as low molecular weight, mainly ascorbic acid) so that a prooxidant/antioxidant imbalance appears. The decrease of corneal antioxidant protective mechanisms results in oxidative injury of the cornea and causes damage of the inner parts of the eye by UVB rays and by reactive oxygen species generated by them.","downloadable_attachments":[{"id":76469526,"asset_id":64425422,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32385248,"first_name":"A.","last_name":"Midelfart","domain_name":"independent","page_name":"AMidelfart","display_name":"A. 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class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/61571206" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="71f9713c2c5079f14ebb49c190075b29" rel="nofollow" data-download="{"attachment_id":74563645,"asset_id":61571206,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/74563645/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" 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href="https://www.academia.edu/Documents/in/Wound_Healing">Wound Healing</a>, <script data-card-contents-for-ri="8991" type="text/json">{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="53510" href="https://www.academia.edu/Documents/in/Cataract_surgery">Cataract surgery</a>, <script data-card-contents-for-ri="53510" type="text/json">{"id":53510,"name":"Cataract surgery","url":"https://www.academia.edu/Documents/in/Cataract_surgery?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" 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surgery","url":"https://www.academia.edu/Documents/in/Cataract_surgery?f_ri=17721","nofollow":false},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=17721"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":401214,"name":"Endothelial 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work_60711240" data-work_id="60711240" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/60711240/Excimer_Laser_Radial_Keratotomy">Excimer Laser Radial Keratotomy</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/60711240" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a89c876f08d1dbd18bcf0aede1566cd6" rel="nofollow" data-download="{"attachment_id":74031850,"asset_id":60711240,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/74031850/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39422474" href="https://independent.academia.edu/StephenTrokel">Stephen Trokel</a><script data-card-contents-for-user="39422474" type="text/json">{"id":39422474,"first_name":"Stephen","last_name":"Trokel","domain_name":"independent","page_name":"StephenTrokel","display_name":"Stephen Trokel","profile_url":"https://independent.academia.edu/StephenTrokel?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_60711240 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="60711240"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 60711240, container: ".js-paper-rank-work_60711240", }); });</script></li><li class="js-percentile-work_60711240 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 60711240; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_60711240"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_60711240 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="60711240"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 60711240; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=60711240]").text(description); $(".js-view-count-work_60711240").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_60711240").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="60711240"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="165" href="https://www.academia.edu/Documents/in/Pathology">Pathology</a>, <script data-card-contents-for-ri="165" type="text/json">{"id":165,"name":"Pathology","url":"https://www.academia.edu/Documents/in/Pathology?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="627" href="https://www.academia.edu/Documents/in/Ophthalmology">Ophthalmology</a>, <script data-card-contents-for-ri="627" type="text/json">{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="647" href="https://www.academia.edu/Documents/in/Surgery">Surgery</a>, <script data-card-contents-for-ri="647" type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="11284" href="https://www.academia.edu/Documents/in/Myopia">Myopia</a><script data-card-contents-for-ri="11284" type="text/json">{"id":11284,"name":"Myopia","url":"https://www.academia.edu/Documents/in/Myopia?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=60711240]'), work: {"id":60711240,"title":"Excimer Laser Radial Keratotomy","created_at":"2021-11-01T08:05:34.589-07:00","url":"https://www.academia.edu/60711240/Excimer_Laser_Radial_Keratotomy?f_ri=17721","dom_id":"work_60711240","summary":null,"downloadable_attachments":[{"id":74031850,"asset_id":60711240,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39422474,"first_name":"Stephen","last_name":"Trokel","domain_name":"independent","page_name":"StephenTrokel","display_name":"Stephen Trokel","profile_url":"https://independent.academia.edu/StephenTrokel?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":165,"name":"Pathology","url":"https://www.academia.edu/Documents/in/Pathology?f_ri=17721","nofollow":false},{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false},{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=17721","nofollow":false},{"id":11284,"name":"Myopia","url":"https://www.academia.edu/Documents/in/Myopia?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721"},{"id":54344,"name":"Methods","url":"https://www.academia.edu/Documents/in/Methods?f_ri=17721"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":247948,"name":"Cadaver","url":"https://www.academia.edu/Documents/in/Cadaver?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=17721"},{"id":591484,"name":"Laser Therapy","url":"https://www.academia.edu/Documents/in/Laser_Therapy?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12014167 coauthored" data-work_id="12014167" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12014167/Arctic_reindeer_extend_their_visual_range_into_the_ultraviolet">Arctic reindeer extend their visual range into the ultraviolet</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12014167" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="10bb5bdf3f410e3b896240c22c6ea7d3" rel="nofollow" data-download="{"attachment_id":46403405,"asset_id":12014167,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46403405/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="55589667" href="https://independent.academia.edu/KaStokkan">K.-a. Stokkan</a><script data-card-contents-for-user="55589667" type="text/json">{"id":55589667,"first_name":"K.-a.","last_name":"Stokkan","domain_name":"independent","page_name":"KaStokkan","display_name":"K.-a. Stokkan","profile_url":"https://independent.academia.edu/KaStokkan?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-12014167">+3</span><div class="hidden js-additional-users-12014167"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/MagellaNeveu">Magella Neveu</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/HoggChris">Chris Hogg</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/RonDouglas">Ron Douglas</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-12014167'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-12014167').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_12014167 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12014167"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12014167, container: ".js-paper-rank-work_12014167", }); });</script></li><li class="js-percentile-work_12014167 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12014167; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_12014167"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_12014167 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="12014167"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12014167; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12014167]").text(description); $(".js-view-count-work_12014167").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_12014167").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12014167"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="38756" href="https://www.academia.edu/Documents/in/Color_Perception">Color Perception</a>, <script data-card-contents-for-ri="38756" type="text/json">{"id":38756,"name":"Color Perception","url":"https://www.academia.edu/Documents/in/Color_Perception?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a>, <script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="51645" href="https://www.academia.edu/Documents/in/Norway">Norway</a><script data-card-contents-for-ri="51645" type="text/json">{"id":51645,"name":"Norway","url":"https://www.academia.edu/Documents/in/Norway?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12014167]'), work: {"id":12014167,"title":"Arctic reindeer extend their visual range into the ultraviolet","created_at":"2015-04-19T12:47:42.548-07:00","url":"https://www.academia.edu/12014167/Arctic_reindeer_extend_their_visual_range_into_the_ultraviolet?f_ri=17721","dom_id":"work_12014167","summary":null,"downloadable_attachments":[{"id":46403405,"asset_id":12014167,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":55589667,"first_name":"K.-a.","last_name":"Stokkan","domain_name":"independent","page_name":"KaStokkan","display_name":"K.-a. Stokkan","profile_url":"https://independent.academia.edu/KaStokkan?f_ri=17721","photo":"/images/s65_no_pic.png"},{"id":29911841,"first_name":"Magella","last_name":"Neveu","domain_name":"independent","page_name":"MagellaNeveu","display_name":"Magella Neveu","profile_url":"https://independent.academia.edu/MagellaNeveu?f_ri=17721","photo":"/images/s65_no_pic.png"},{"id":30078371,"first_name":"Chris","last_name":"Hogg","domain_name":"independent","page_name":"HoggChris","display_name":"Chris Hogg","profile_url":"https://independent.academia.edu/HoggChris?f_ri=17721","photo":"https://0.academia-photos.com/30078371/122708129/112051101/s65_chris.hogg.jpg"},{"id":30051649,"first_name":"Ron","last_name":"Douglas","domain_name":"independent","page_name":"RonDouglas","display_name":"Ron Douglas","profile_url":"https://independent.academia.edu/RonDouglas?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":38756,"name":"Color Perception","url":"https://www.academia.edu/Documents/in/Color_Perception?f_ri=17721","nofollow":false},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=17721","nofollow":false},{"id":51645,"name":"Norway","url":"https://www.academia.edu/Documents/in/Norway?f_ri=17721","nofollow":false},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":158384,"name":"Reindeer","url":"https://www.academia.edu/Documents/in/Reindeer?f_ri=17721"},{"id":301347,"name":"Opsins","url":"https://www.academia.edu/Documents/in/Opsins?f_ri=17721"},{"id":649451,"name":"Seasons","url":"https://www.academia.edu/Documents/in/Seasons?f_ri=17721"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence?f_ri=17721"},{"id":1764230,"name":"Experimental Biology","url":"https://www.academia.edu/Documents/in/Experimental_Biology?f_ri=17721"},{"id":2467566,"name":"Molecular Sequence Data","url":"https://www.academia.edu/Documents/in/Molecular_Sequence_Data?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12350520" data-work_id="12350520" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12350520/Optical_projection_mires_for_measurements_of_the_radii_of_curvature_of_the_cornea_in_biomicroscopes">Optical projection mires for measurements of the radii of curvature of the cornea in biomicroscopes</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Keratometry is currently achieved by projecting a circular mire onto the patient&#39;s cornea and analyzing the size and shape of its reflected image. The projection mires are decisive for the precision of the measurement. We have... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12350520" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Keratometry is currently achieved by projecting a circular mire onto the patient&#39;s cornea and analyzing the size and shape of its reflected image. The projection mires are decisive for the precision of the measurement. We have previously developed a keratometric module for slit lamps, and the development of four projection mires are presented. Mire 1 is composed of optical fibers and electrical cables; Mire 2, 48 LEDs; Mire 3, optical fibers and no electrical cables; and Mire 4, mechanical parts--cable free. Mires 2-4 provide accurate keratometry measurements at slit lamps. Mire 4 is the most adequate for the clinical environment.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12350520" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="104932621f310c1f559af5c85422e9f3" rel="nofollow" data-download="{"attachment_id":46229773,"asset_id":12350520,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46229773/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31044056" href="https://usp-br.academia.edu/LilianeVentura">Liliane Ventura</a><script data-card-contents-for-user="31044056" type="text/json">{"id":31044056,"first_name":"Liliane","last_name":"Ventura","domain_name":"usp-br","page_name":"LilianeVentura","display_name":"Liliane Ventura","profile_url":"https://usp-br.academia.edu/LilianeVentura?f_ri=17721","photo":"https://0.academia-photos.com/31044056/72836714/61308341/s65_liliane.ventura.jpg"}</script></span></span></li><li class="js-paper-rank-work_12350520 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12350520"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12350520, container: ".js-paper-rank-work_12350520", }); 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The projection mires are decisive for the precision of the measurement. We have previously developed a keratometric module for slit lamps, and the development of four projection mires are presented. Mire 1 is composed of optical fibers and electrical cables; Mire 2, 48 LEDs; Mire 3, optical fibers and no electrical cables; and Mire 4, mechanical parts--cable free. Mires 2-4 provide accurate keratometry measurements at slit lamps. Mire 4 is the most adequate for the clinical environment.","downloadable_attachments":[{"id":46229773,"asset_id":12350520,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31044056,"first_name":"Liliane","last_name":"Ventura","domain_name":"usp-br","page_name":"LilianeVentura","display_name":"Liliane Ventura","profile_url":"https://usp-br.academia.edu/LilianeVentura?f_ri=17721","photo":"https://0.academia-photos.com/31044056/72836714/61308341/s65_liliane.ventura.jpg"}],"research_interests":[{"id":60,"name":"Mechanical Engineering","url":"https://www.academia.edu/Documents/in/Mechanical_Engineering?f_ri=17721","nofollow":false},{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false},{"id":2066,"name":"Research Design","url":"https://www.academia.edu/Documents/in/Research_Design?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721"},{"id":66379,"name":"Automation","url":"https://www.academia.edu/Documents/in/Automation?f_ri=17721"},{"id":234350,"name":"Applied Optics","url":"https://www.academia.edu/Documents/in/Applied_Optics?f_ri=17721"},{"id":263152,"name":"Optical physics","url":"https://www.academia.edu/Documents/in/Optical_physics?f_ri=17721"},{"id":404996,"name":"Optical fiber","url":"https://www.academia.edu/Documents/in/Optical_fiber?f_ri=17721"},{"id":548472,"name":"Optics and Photonics","url":"https://www.academia.edu/Documents/in/Optics_and_Photonics?f_ri=17721"},{"id":1145520,"name":"Equipment Design","url":"https://www.academia.edu/Documents/in/Equipment_Design?f_ri=17721"},{"id":1161531,"name":"Corneal 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class="clearfix u-pv7x u-mb0x js-work-card work_66804197" data-work_id="66804197" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/66804197/Small_Fibers_Peripheral_Neuropathy_in_Wilson_Disease_an_In_Vivo_Documentation_by_Corneal_Confocal_Microscopy">Small Fibers Peripheral Neuropathy in Wilson Disease: an In Vivo Documentation by Corneal Confocal Microscopy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: Wilson disease (WD) is a disorder of hepatic copper metabolism leading to copper accumulation in hepatocytes and in extrahepatic organs, as the brain and the cornea. The aim of this study was to investigate central corneal... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_66804197" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: Wilson disease (WD) is a disorder of hepatic copper metabolism leading to copper accumulation in hepatocytes and in extrahepatic organs, as the brain and the cornea. The aim of this study was to investigate central corneal changes and in particular to assess the parameters of corneal sub-basal nerve plexus (SBNP) in patients affected by WD, using corneal confocal microscopy (CCM). Twenty-four patients affected by WD and 24 healthy control subjects were incuded in this cross-sectional comparative study. One eye of each subject was examined to quantify different corneal parameters. Mean cell diameter and mean cell density of the epithelium; number of fibers (NF), nerve fiber length density (NFLD), number of branchings (NBr), number of beadings (NBe) and fiber tortuosity (FT) of the SBNP; mean cell density of keratocytes of the anterior, medium and posterior stroma and mean cell density, polimegatism and pleomorphism of the endothelium and central corneal sensitivity were anal...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/66804197" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="240a43a9c7bd6bcf9f9d8455f590a308" rel="nofollow" data-download="{"attachment_id":77855602,"asset_id":66804197,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/77855602/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="52495617" href="https://independent.academia.edu/MariannaBerton">Marianna Berton</a><script data-card-contents-for-user="52495617" type="text/json">{"id":52495617,"first_name":"Marianna","last_name":"Berton","domain_name":"independent","page_name":"MariannaBerton","display_name":"Marianna Berton","profile_url":"https://independent.academia.edu/MariannaBerton?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_66804197 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="66804197"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 66804197, container: ".js-paper-rank-work_66804197", }); 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Mean cell diameter and mean cell density of the epithelium; number of fibers (NF), nerve fiber length density (NFLD), number of branchings (NBr), number of beadings (NBe) and fiber tortuosity (FT) of the SBNP; mean cell density of keratocytes of the anterior, medium and posterior stroma and mean cell density, polimegatism and pleomorphism of the endothelium and central corneal sensitivity were anal...","downloadable_attachments":[{"id":77855602,"asset_id":66804197,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":52495617,"first_name":"Marianna","last_name":"Berton","domain_name":"independent","page_name":"MariannaBerton","display_name":"Marianna Berton","profile_url":"https://independent.academia.edu/MariannaBerton?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":18533,"name":"Confocal 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surgery","url":"https://www.academia.edu/Documents/in/Cataract_surgery?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":114855,"name":"Astigmatism","url":"https://www.academia.edu/Documents/in/Astigmatism?f_ri=17721"},{"id":144034,"name":"Cataract","url":"https://www.academia.edu/Documents/in/Cataract?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=17721"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=17721"},{"id":866913,"name":"Phacoemulsification","url":"https://www.academia.edu/Documents/in/Phacoemulsification?f_ri=17721"},{"id":990198,"name":"Retrospective Study","url":"https://www.academia.edu/Documents/in/Retrospective_Study?f_ri=17721"},{"id":2463621,"name":"Postoperative Complications","url":"https://www.academia.edu/Documents/in/Postoperative_Complications?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8651862" data-work_id="8651862" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8651862/Spot_size_and_quality_of_scanning_laser_correction_of_higher_order_wavefront_aberrations">Spot size and quality of scanning laser correction of higher-order wavefront aberrations</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8651862" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="60ae4342ff51fb61169bab62d83ccd1f" rel="nofollow" data-download="{"attachment_id":48030984,"asset_id":8651862,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48030984/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="18050873" href="https://independent.academia.edu/MuhammadArif176">Muhammad Arif</a><script data-card-contents-for-user="18050873" type="text/json">{"id":18050873,"first_name":"Muhammad","last_name":"Arif","domain_name":"independent","page_name":"MuhammadArif176","display_name":"Muhammad 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$(".js-view-count-work_8651862").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8651862"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="43860" href="https://www.academia.edu/Documents/in/Refractive_Surgery">Refractive Surgery</a>, <script data-card-contents-for-ri="43860" type="text/json">{"id":43860,"name":"Refractive Surgery","url":"https://www.academia.edu/Documents/in/Refractive_Surgery?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="49247" href="https://www.academia.edu/Documents/in/Higher_Order_Thinking">Higher Order Thinking</a>, <script data-card-contents-for-ri="49247" type="text/json">{"id":49247,"name":"Higher Order Thinking","url":"https://www.academia.edu/Documents/in/Higher_Order_Thinking?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a><script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8651862]'), work: {"id":8651862,"title":"Spot size and quality of scanning laser correction of higher-order 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Surgery","url":"https://www.academia.edu/Documents/in/Refractive_Surgery?f_ri=17721","nofollow":false},{"id":49247,"name":"Higher Order Thinking","url":"https://www.academia.edu/Documents/in/Higher_Order_Thinking?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false},{"id":69542,"name":"Computer Simulation","url":"https://www.academia.edu/Documents/in/Computer_Simulation?f_ri=17721"},{"id":157261,"name":"Photorefractive keratectomy","url":"https://www.academia.edu/Documents/in/Photorefractive_keratectomy?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":343667,"name":"Theoretical Models","url":"https://www.academia.edu/Documents/in/Theoretical_Models?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25718932" data-work_id="25718932" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25718932/The_Effect_of_Different_2_4_D_Doses_on_Callus_Induction_and_Chromosomal_Structure_in_Maize_Zea_Mays_L">The Effect of Different 2, 4-D Doses on Callus Induction and Chromosomal Structure in Maize (Zea Mays L</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In the stage of in vitro of this research which was arranged in vitro and in vivo media, the effect on callus induction and plant regeneration in 6 different varieties of 2,4-D doses (0, 2, 4, 6, 8 and 10 mg/l) through callus culture was... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_25718932" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In the stage of in vitro of this research which was arranged in vitro and in vivo media, the effect on callus induction and plant regeneration in 6 different varieties of 2,4-D doses (0, 2, 4, 6, 8 and 10 mg/l) through callus culture was investigated. In the stage of in vivo, samples from the root tips composed of the callus of all maize varieties were taken, and the changes observed in the chromosomal numbers in maize lines were evaluated. As a result of the microscopic analyses of the root tips obtained through the application of 2,4-D auxin in different corn varieties in different doses, changes were observed in the chromosomal numbers of Pioneer 31N27 (2n=18), Pioneer 3223 (2n=19) and Pioneer 34N24 (2n=19) maize varieties. Mitotic anomaly observed through the application of 2,4-D was established as aneuploidy (the change of the chromosomal number in genome) and it was found to form as the decrease of the chromosomal number (hipoploidy). According to the data found, the dose of 2,4-D to be used in the transgenic maize producing studies to be utilized in Turkey was determined to be 2 mg/l providing the highest callus formation ratio but causing no chromosomal deviations.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25718932" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="78b3ea3fadbd67542e321e71e002cf6f" rel="nofollow" data-download="{"attachment_id":46066762,"asset_id":25718932,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46066762/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31785042" href="https://ijoer.academia.edu/IJOERResearchJournal">Engineering Journal Publication of Research work</a><script data-card-contents-for-user="31785042" type="text/json">{"id":31785042,"first_name":"Engineering Journal","last_name":"Publication of Research work","domain_name":"ijoer","page_name":"IJOERResearchJournal","display_name":"Engineering Journal Publication of Research work","profile_url":"https://ijoer.academia.edu/IJOERResearchJournal?f_ri=17721","photo":"https://0.academia-photos.com/31785042/9436714/10515385/s65_ijoer.research_journal.png"}</script></span></span></li><li class="js-paper-rank-work_25718932 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25718932"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25718932, container: ".js-paper-rank-work_25718932", }); 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$(".js-view-count[data-work-id=25718932]").text(description); $(".js-view-count-work_25718932").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25718932").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25718932"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="48" href="https://www.academia.edu/Documents/in/Engineering">Engineering</a>, <script data-card-contents-for-ri="48" type="text/json">{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="19870" href="https://www.academia.edu/Documents/in/Research">Research</a>, <script data-card-contents-for-ri="19870" type="text/json">{"id":19870,"name":"Research","url":"https://www.academia.edu/Documents/in/Research?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="84384" href="https://www.academia.edu/Documents/in/Maize">Maize</a><script data-card-contents-for-ri="84384" type="text/json">{"id":84384,"name":"Maize","url":"https://www.academia.edu/Documents/in/Maize?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25718932]'), work: {"id":25718932,"title":"The Effect of Different 2, 4-D Doses on Callus Induction and Chromosomal Structure in Maize (Zea Mays L","created_at":"2016-05-30T04:19:59.893-07:00","url":"https://www.academia.edu/25718932/The_Effect_of_Different_2_4_D_Doses_on_Callus_Induction_and_Chromosomal_Structure_in_Maize_Zea_Mays_L?f_ri=17721","dom_id":"work_25718932","summary":"In the stage of in vitro of this research which was arranged in vitro and in vivo media, the effect on callus induction and plant regeneration in 6 different varieties of 2,4-D doses (0, 2, 4, 6, 8 and 10 mg/l) through callus culture was investigated. In the stage of in vivo, samples from the root tips composed of the callus of all maize varieties were taken, and the changes observed in the chromosomal numbers in maize lines were evaluated. As a result of the microscopic analyses of the root tips obtained through the application of 2,4-D auxin in different corn varieties in different doses, changes were observed in the chromosomal numbers of Pioneer 31N27 (2n=18), Pioneer 3223 (2n=19) and Pioneer 34N24 (2n=19) maize varieties. Mitotic anomaly observed through the application of 2,4-D was established as aneuploidy (the change of the chromosomal number in genome) and it was found to form as the decrease of the chromosomal number (hipoploidy). According to the data found, the dose of 2,4-D to be used in the transgenic maize producing studies to be utilized in Turkey was determined to be 2 mg/l providing the highest callus formation ratio but causing no chromosomal deviations.","downloadable_attachments":[{"id":46066762,"asset_id":25718932,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31785042,"first_name":"Engineering Journal","last_name":"Publication of Research work","domain_name":"ijoer","page_name":"IJOERResearchJournal","display_name":"Engineering Journal Publication of Research work","profile_url":"https://ijoer.academia.edu/IJOERResearchJournal?f_ri=17721","photo":"https://0.academia-photos.com/31785042/9436714/10515385/s65_ijoer.research_journal.png"}],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":19870,"name":"Research","url":"https://www.academia.edu/Documents/in/Research?f_ri=17721","nofollow":false},{"id":84384,"name":"Maize","url":"https://www.academia.edu/Documents/in/Maize?f_ri=17721","nofollow":false},{"id":370863,"name":"Zea mays","url":"https://www.academia.edu/Documents/in/Zea_mays?f_ri=17721"},{"id":740938,"name":"Callus induction","url":"https://www.academia.edu/Documents/in/Callus_induction?f_ri=17721"},{"id":2471267,"name":"Chromosomal Number","url":"https://www.academia.edu/Documents/in/Chromosomal_Number?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16392926 coauthored" data-work_id="16392926" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16392926/Combined_3DISCO_clearing_method_retrograde_tracer_and_ultramicroscopy_to_map_corneal_neurons_in_a_whole_adult_mouse_trigeminal_ganglion">Combined 3DISCO clearing method, retrograde tracer and ultramicroscopy to map corneal neurons in a whole adult mouse trigeminal ganglion</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Tissue clearing and subsequent imaging of intact transparent tissues have provided an innovative way to analyze anatomical pathways in the nervous system. In this study, we combined a recent 3-dimensional imaging of solvent cleared organ... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16392926" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Tissue clearing and subsequent imaging of intact transparent tissues have provided an innovative way to analyze anatomical pathways in the nervous system. In this study, we combined a recent 3-dimensional imaging of solvent cleared organ (3DISCO) procedure, light-sheet microscopy, fluorescent retrograde tracer, and Imaris software to 3D map corneal sensory neurons within a whole adult mouse trigeminal ganglion (TG). We first established the optimized steps to easily and rapidly clear a fixed TG. We found that the 3DISCO procedure gave excellent results and took less than 3 h to clear the TG. In a second set of experiments, a retrograde tracer (cholera toxin B Alexa 594-conjugated) was applied to de-epithelialized cornea to retrograde-labeled corneal sensory neurons. Two days later, TGs were cleared by the 3DISCO method and serial imaging was performed using light-sheet ultramicroscopic technology. High-resolution images of labeled neurons can be easily and rapidly obtained from a 3D...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16392926" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7ab7cde77693b4a4558ad3ec62a2b508" rel="nofollow" data-download="{"attachment_id":42502736,"asset_id":16392926,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42502736/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35529701" href="https://independent.academia.edu/HanenKhabou">Hanen Khabou</a><script data-card-contents-for-user="35529701" type="text/json">{"id":35529701,"first_name":"Hanen","last_name":"Khabou","domain_name":"independent","page_name":"HanenKhabou","display_name":"Hanen Khabou","profile_url":"https://independent.academia.edu/HanenKhabou?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-16392926">+1</span><div class="hidden js-additional-users-16392926"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://cearc.academia.edu/ChristopheBaudouin">Christophe Baudouin</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-16392926'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-16392926').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_16392926 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16392926"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16392926, container: ".js-paper-rank-work_16392926", }); });</script></li><li class="js-percentile-work_16392926 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 16392926; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_16392926"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_16392926 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="16392926"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 16392926; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=16392926]").text(description); $(".js-view-count-work_16392926").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_16392926").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="16392926"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="3091" href="https://www.academia.edu/Documents/in/Microscopy">Microscopy</a>, <script data-card-contents-for-ri="3091" type="text/json">{"id":3091,"name":"Microscopy","url":"https://www.academia.edu/Documents/in/Microscopy?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="82660" href="https://www.academia.edu/Documents/in/Sensation">Sensation</a>, <script data-card-contents-for-ri="82660" type="text/json">{"id":82660,"name":"Sensation","url":"https://www.academia.edu/Documents/in/Sensation?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="84760" href="https://www.academia.edu/Documents/in/Mice">Mice</a><script data-card-contents-for-ri="84760" type="text/json">{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=16392926]'), work: {"id":16392926,"title":"Combined 3DISCO clearing method, retrograde tracer and ultramicroscopy to map corneal neurons in a whole adult mouse trigeminal ganglion","created_at":"2015-10-02T01:53:09.535-07:00","url":"https://www.academia.edu/16392926/Combined_3DISCO_clearing_method_retrograde_tracer_and_ultramicroscopy_to_map_corneal_neurons_in_a_whole_adult_mouse_trigeminal_ganglion?f_ri=17721","dom_id":"work_16392926","summary":"Tissue clearing and subsequent imaging of intact transparent tissues have provided an innovative way to analyze anatomical pathways in the nervous system. In this study, we combined a recent 3-dimensional imaging of solvent cleared organ (3DISCO) procedure, light-sheet microscopy, fluorescent retrograde tracer, and Imaris software to 3D map corneal sensory neurons within a whole adult mouse trigeminal ganglion (TG). We first established the optimized steps to easily and rapidly clear a fixed TG. We found that the 3DISCO procedure gave excellent results and took less than 3 h to clear the TG. In a second set of experiments, a retrograde tracer (cholera toxin B Alexa 594-conjugated) was applied to de-epithelialized cornea to retrograde-labeled corneal sensory neurons. Two days later, TGs were cleared by the 3DISCO method and serial imaging was performed using light-sheet ultramicroscopic technology. High-resolution images of labeled neurons can be easily and rapidly obtained from a 3D...","downloadable_attachments":[{"id":42502736,"asset_id":16392926,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35529701,"first_name":"Hanen","last_name":"Khabou","domain_name":"independent","page_name":"HanenKhabou","display_name":"Hanen Khabou","profile_url":"https://independent.academia.edu/HanenKhabou?f_ri=17721","photo":"/images/s65_no_pic.png"},{"id":35674458,"first_name":"Christophe","last_name":"Baudouin","domain_name":"cearc","page_name":"ChristopheBaudouin","display_name":"Christophe Baudouin","profile_url":"https://cearc.academia.edu/ChristopheBaudouin?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3091,"name":"Microscopy","url":"https://www.academia.edu/Documents/in/Microscopy?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":82660,"name":"Sensation","url":"https://www.academia.edu/Documents/in/Sensation?f_ri=17721","nofollow":false},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=17721","nofollow":false},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":123287,"name":"Three Dimensional Imaging","url":"https://www.academia.edu/Documents/in/Three_Dimensional_Imaging?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_67513591" data-work_id="67513591" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/67513591/SkQ1_Ophthalmic_Solution_for_Dry_Eye_Treatment_Results_of_a_Phase_2_Safety_and_Efficacy_Clinical_Study_in_the_Environment_and_During_Challenge_in_the_Controlled_Adverse_Environment_Model">SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study in the Environment and During Challenge in the Controlled Adverse Environment Model</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. In a single-center, randomized, double-masked, placebo-controlled,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_67513591" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. In a single-center, randomized, double-masked, placebo-controlled, 29-day study, 91 subjects with mild to moderate dry eye instilled the study drug twice daily and recorded dry eye symptoms daily. Subjects were randomized 1:1:1 into one of three ophthalmic solution treatment groups: SkQ1 1.55 µg/mL, SkQ1 0.155 µg/mL, or 0.0 µg/mL (placebo). Subjects were exposed to a controlled adverse environment chamber at 3 of the 4 study visits (Day -7, Day 1, and Day 29). Investigator assessments occurred at all study visits. SkQ1 was safe and efficacious in treating dry eye signs and symptoms. Statistically significant improvements with SkQ1 compared to placebo occurred for the dry eye signs of corneal fluorescein staining and lissamine green staining in the central region and lid margin redness, and for the dry eye symptoms of oc...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/67513591" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a0fd3972cdf3bb2e17d252e1977d5a40" rel="nofollow" data-download="{"attachment_id":78300731,"asset_id":67513591,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/78300731/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37075617" href="https://independent.academia.edu/MaximSkulachev">Maxim Skulachev</a><script data-card-contents-for-user="37075617" type="text/json">{"id":37075617,"first_name":"Maxim","last_name":"Skulachev","domain_name":"independent","page_name":"MaximSkulachev","display_name":"Maxim Skulachev","profile_url":"https://independent.academia.edu/MaximSkulachev?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_67513591 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="67513591"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 67513591, container: ".js-paper-rank-work_67513591", }); });</script></li><li class="js-percentile-work_67513591 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 67513591; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_67513591"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_67513591 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="67513591"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 67513591; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=67513591]").text(description); $(".js-view-count-work_67513591").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_67513591").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="67513591"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=67513591]'), work: {"id":67513591,"title":"SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study in the Environment and During Challenge in the Controlled Adverse Environment Model","created_at":"2022-01-07T04:17:21.293-08:00","url":"https://www.academia.edu/67513591/SkQ1_Ophthalmic_Solution_for_Dry_Eye_Treatment_Results_of_a_Phase_2_Safety_and_Efficacy_Clinical_Study_in_the_Environment_and_During_Challenge_in_the_Controlled_Adverse_Environment_Model?f_ri=17721","dom_id":"work_67513591","summary":"This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. In a single-center, randomized, double-masked, placebo-controlled, 29-day study, 91 subjects with mild to moderate dry eye instilled the study drug twice daily and recorded dry eye symptoms daily. Subjects were randomized 1:1:1 into one of three ophthalmic solution treatment groups: SkQ1 1.55 µg/mL, SkQ1 0.155 µg/mL, or 0.0 µg/mL (placebo). Subjects were exposed to a controlled adverse environment chamber at 3 of the 4 study visits (Day -7, Day 1, and Day 29). Investigator assessments occurred at all study visits. SkQ1 was safe and efficacious in treating dry eye signs and symptoms. Statistically significant improvements with SkQ1 compared to placebo occurred for the dry eye signs of corneal fluorescein staining and lissamine green staining in the central region and lid margin redness, and for the dry eye symptoms of oc...","downloadable_attachments":[{"id":78300731,"asset_id":67513591,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37075617,"first_name":"Maxim","last_name":"Skulachev","domain_name":"independent","page_name":"MaximSkulachev","display_name":"Maxim Skulachev","profile_url":"https://independent.academia.edu/MaximSkulachev?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=17721","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721"},{"id":100657,"name":"Therapy","url":"https://www.academia.edu/Documents/in/Therapy?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=17721"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=17721"},{"id":1137112,"name":"Ophthalmic Solutions","url":"https://www.academia.edu/Documents/in/Ophthalmic_Solutions?f_ri=17721"},{"id":1923219,"name":"Fluorescein","url":"https://www.academia.edu/Documents/in/Fluorescein?f_ri=17721"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8351184" data-work_id="8351184" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8351184/Automated_keratometry_at_low_cost">Automated keratometry at low cost</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Describes an automatic optical system that is attached to a slit lamp in order to provide automatic keratometry at low cost. The system consists of projecting a light ring as a target onto the patient's cornea as well as analysis of the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8351184" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Describes an automatic optical system that is attached to a slit lamp in order to provide automatic keratometry at low cost. The system consists of projecting a light ring as a target onto the patient's cornea as well as analysis of the deformation of the target in order to obtain the radius of curvature and the axis of the associated astigmatism. The reflected image of the target is displayed on a PC monitor, while dedicated software performs the analysis of the image, which provides the corneal keratometry</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8351184" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="817ef6903bebca5d9f1b989e94810ee6" rel="nofollow" data-download="{"attachment_id":48126877,"asset_id":8351184,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48126877/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="16747802" href="https://independent.academia.edu/LilianVentura">Lilian Ventura</a><script data-card-contents-for-user="16747802" type="text/json">{"id":16747802,"first_name":"Lilian","last_name":"Ventura","domain_name":"independent","page_name":"LilianVentura","display_name":"Lilian Ventura","profile_url":"https://independent.academia.edu/LilianVentura?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8351184 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8351184"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8351184, container: ".js-paper-rank-work_8351184", }); });</script></li><li class="js-percentile-work_8351184 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 8351184; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_8351184"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_8351184 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="8351184"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 8351184; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=8351184]").text(description); $(".js-view-count-work_8351184").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8351184").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8351184"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1131" href="https://www.academia.edu/Documents/in/Biomedical_Engineering">Biomedical Engineering</a>, <script data-card-contents-for-ri="1131" type="text/json">{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a><script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8351184]'), work: {"id":8351184,"title":"Automated keratometry at low cost","created_at":"2014-09-16T07:17:54.192-07:00","url":"https://www.academia.edu/8351184/Automated_keratometry_at_low_cost?f_ri=17721","dom_id":"work_8351184","summary":"Describes an automatic optical system that is attached to a slit lamp in order to provide automatic keratometry at low cost. The system consists of projecting a light ring as a target onto the patient's cornea as well as analysis of the deformation of the target in order to obtain the radius of curvature and the axis of the associated astigmatism. The reflected image of the target is displayed on a PC monitor, while dedicated software performs the analysis of the image, which provides the corneal keratometry","downloadable_attachments":[{"id":48126877,"asset_id":8351184,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":16747802,"first_name":"Lilian","last_name":"Ventura","domain_name":"independent","page_name":"LilianVentura","display_name":"Lilian Ventura","profile_url":"https://independent.academia.edu/LilianVentura?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false},{"id":245634,"name":"Eye","url":"https://www.academia.edu/Documents/in/Eye?f_ri=17721"},{"id":1161531,"name":"Corneal topography","url":"https://www.academia.edu/Documents/in/Corneal_topography?f_ri=17721"},{"id":1237788,"name":"Electrical And Electronic Engineering","url":"https://www.academia.edu/Documents/in/Electrical_And_Electronic_Engineering?f_ri=17721"},{"id":1771673,"name":"Software Performance","url":"https://www.academia.edu/Documents/in/Software_Performance?f_ri=17721"},{"id":2028950,"name":"Automatic test equipment (ATE)","url":"https://www.academia.edu/Documents/in/Automatic_test_equipment_ATE_?f_ri=17721"},{"id":2513364,"name":"Radius of Curvature","url":"https://www.academia.edu/Documents/in/Radius_of_Curvature?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_68711814" data-work_id="68711814" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/68711814/Increased_Langerhan_cell_density_and_corneal_nerve_damage_in_diabetic_patients_Role_of_immune_mechanisms_in_human_diabetic_neuropathy">Increased Langerhan cell density and corneal nerve damage in diabetic patients: Role of immune mechanisms in human diabetic neuropathy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Aim/hypothesisImmune mechanisms have been proposed to play a role in the development of diabetic neuropathy. We employed in vivo corneal confocal microscopy (CCM) to quantify the presence and density of Langerhans cells (LCs) in relation... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_68711814" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Aim/hypothesisImmune mechanisms have been proposed to play a role in the development of diabetic neuropathy. We employed in vivo corneal confocal microscopy (CCM) to quantify the presence and density of Langerhans cells (LCs) in relation to the extent of corneal nerve damage in Bowman&#x27;s layer of the cornea in diabetic patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/68711814" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f5b354837f577a7f1c6afe37ddcc4925" rel="nofollow" data-download="{"attachment_id":79094202,"asset_id":68711814,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/79094202/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51837374" href="https://weillcornell.academia.edu/RayazMalik">Rayaz Malik</a><script data-card-contents-for-user="51837374" type="text/json">{"id":51837374,"first_name":"Rayaz","last_name":"Malik","domain_name":"weillcornell","page_name":"RayazMalik","display_name":"Rayaz Malik","profile_url":"https://weillcornell.academia.edu/RayazMalik?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_68711814 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="68711814"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 68711814, container: ".js-paper-rank-work_68711814", }); 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We employed in vivo corneal confocal microscopy (CCM) to quantify the presence and density of Langerhans cells (LCs) in relation to the extent of corneal nerve damage in Bowman\u0026#x27;s layer of the cornea in diabetic patients.","downloadable_attachments":[{"id":79094202,"asset_id":68711814,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51837374,"first_name":"Rayaz","last_name":"Malik","domain_name":"weillcornell","page_name":"RayazMalik","display_name":"Rayaz Malik","profile_url":"https://weillcornell.academia.edu/RayazMalik?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":18533,"name":"Confocal Microscopy","url":"https://www.academia.edu/Documents/in/Confocal_Microscopy?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721","nofollow":false},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":209529,"name":"Diabetic Neuropathy","url":"https://www.academia.edu/Documents/in/Diabetic_Neuropathy?f_ri=17721"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=17721"},{"id":306781,"name":"DCs","url":"https://www.academia.edu/Documents/in/DCs?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":852944,"name":"Langerhans cells","url":"https://www.academia.edu/Documents/in/Langerhans_cells?f_ri=17721"},{"id":2796077,"name":"Cell count","url":"https://www.academia.edu/Documents/in/Cell_count?f_ri=17721"},{"id":2921997,"name":"Diabetic Neuropathies","url":"https://www.academia.edu/Documents/in/Diabetic_Neuropathies?f_ri=17721"},{"id":3952711,"name":"NFT","url":"https://www.academia.edu/Documents/in/NFT?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_28818326" data-work_id="28818326" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/28818326/Distribution_of_Tritiated_Benzylpenicillin_in_the_Rabbit_Eye">Distribution of Tritiated Benzylpenicillin in the Rabbit Eye</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28818326" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b9dd00c1f905e2b7c8c72389bc34fdd5" rel="nofollow" data-download="{"attachment_id":49238648,"asset_id":28818326,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49238648/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="54261315" href="https://independent.academia.edu/ToivanenP">P. 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href="https://www.academia.edu/15859430/Genetic_dissection_of_Pax6_dosage_requirements_in_the_developing_mouse_eye">Genetic dissection of Pax6 dosage requirements in the developing mouse eye</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15859430" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e02007b95b00b91ebf1f13fee8ba56b2" rel="nofollow" data-download="{"attachment_id":42850624,"asset_id":15859430,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm 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href="https://www.academia.edu/Documents/in/Morphogenesis">Morphogenesis</a>, <script data-card-contents-for-ri="24124" type="text/json">{"id":24124,"name":"Morphogenesis","url":"https://www.academia.edu/Documents/in/Morphogenesis?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a><script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15859430]'), work: {"id":15859430,"title":"Genetic dissection of Pax6 dosage requirements in the developing mouse 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Ashery-Padan","profile_url":"https://independent.academia.edu/RuthAsheryPadan?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":24124,"name":"Morphogenesis","url":"https://www.academia.edu/Documents/in/Morphogenesis?f_ri=17721","nofollow":false},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=17721","nofollow":false},{"id":60436,"name":"Cell Differentiation","url":"https://www.academia.edu/Documents/in/Cell_Differentiation?f_ri=17721"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=17721"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals?f_ri=17721"},{"id":116160,"name":"Human Molecular Genetics","url":"https://www.academia.edu/Documents/in/Human_Molecular_Genetics?f_ri=17721"},{"id":194433,"name":"Gene Dosage","url":"https://www.academia.edu/Documents/in/Gene_Dosage?f_ri=17721"},{"id":213897,"name":"Phenotype","url":"https://www.academia.edu/Documents/in/Phenotype?f_ri=17721"},{"id":372410,"name":"Genotype","url":"https://www.academia.edu/Documents/in/Genotype?f_ri=17721"},{"id":619723,"name":"Iris","url":"https://www.academia.edu/Documents/in/Iris?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22001974" data-work_id="22001974" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22001974/Comparison_of_Apoptosis_and_Terminal_Differentiation_The_Mammalian_Aging_Process">Comparison of Apoptosis and Terminal Differentiation: The Mammalian Aging Process</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22001974" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="860d99ab832408383e5fbd74c67d7936" rel="nofollow" data-download="{"attachment_id":42703990,"asset_id":22001974,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42703990/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="43260463" href="https://independent.academia.edu/ClaudeGagna">Claude E Gagna</a><script data-card-contents-for-user="43260463" type="text/json">{"id":43260463,"first_name":"Claude","last_name":"Gagna","domain_name":"independent","page_name":"ClaudeGagna","display_name":"Claude E 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$(".js-percentile-work_22001974"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22001974 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22001974"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22001974; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22001974]").text(description); $(".js-view-count-work_22001974").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22001974").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22001974"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6791" href="https://www.academia.edu/Documents/in/Aging">Aging</a>, <script data-card-contents-for-ri="6791" type="text/json">{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12071" href="https://www.academia.edu/Documents/in/Immunohistochemistry">Immunohistochemistry</a>, <script data-card-contents-for-ri="12071" type="text/json">{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="24731" href="https://www.academia.edu/Documents/in/Apoptosis">Apoptosis</a><script data-card-contents-for-ri="24731" type="text/json">{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22001974]'), work: {"id":22001974,"title":"Comparison of Apoptosis and Terminal Differentiation: The Mammalian Aging 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Gagna","profile_url":"https://independent.academia.edu/ClaudeGagna?f_ri=17721","photo":"https://0.academia-photos.com/43260463/169562713/159537922/s65_claude.gagna.jpg"}],"research_interests":[{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=17721","nofollow":false},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis?f_ri=17721","nofollow":false},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals?f_ri=17721"},{"id":112576,"name":"Cell Death","url":"https://www.academia.edu/Documents/in/Cell_Death?f_ri=17721"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=17721"},{"id":289683,"name":"DNA content","url":"https://www.academia.edu/Documents/in/DNA_content?f_ri=17721"},{"id":485556,"name":"Guinea Pig","url":"https://www.academia.edu/Documents/in/Guinea_Pig?f_ri=17721"},{"id":1036479,"name":"Fixatives","url":"https://www.academia.edu/Documents/in/Fixatives?f_ri=17721"},{"id":1939264,"name":"single stranded DNA","url":"https://www.academia.edu/Documents/in/single_stranded_DNA?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27222378" data-work_id="27222378" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27222378/Sensitivity_and_Specificity_of_Posterior_Corneal_Elevation_Measured_by_Pentacam_in_Discriminating_Keratoconus_Subclinical_Keratoconus">Sensitivity and Specificity of Posterior Corneal Elevation Measured by Pentacam in Discriminating Keratoconus/Subclinical Keratoconus</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27222378" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="926e636a78ac989d2b2b26b9051301a9" rel="nofollow" data-download="{"attachment_id":47479770,"asset_id":27222378,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47479770/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51306740" href="https://independent.academia.edu/DavideTurco1">Davide Turco</a><script data-card-contents-for-user="51306740" type="text/json">{"id":51306740,"first_name":"Davide","last_name":"Turco","domain_name":"independent","page_name":"DavideTurco1","display_name":"Davide Turco","profile_url":"https://independent.academia.edu/DavideTurco1?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_27222378 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="27222378"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 27222378, container: ".js-paper-rank-work_27222378", }); });</script></li><li class="js-percentile-work_27222378 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 27222378; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_27222378"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_27222378 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="27222378"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27222378; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27222378]").text(description); $(".js-view-count-work_27222378").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_27222378").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="27222378"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">19</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="627" href="https://www.academia.edu/Documents/in/Ophthalmology">Ophthalmology</a>, <script data-card-contents-for-ri="627" type="text/json">{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1589" href="https://www.academia.edu/Documents/in/Photography">Photography</a>, <script data-card-contents-for-ri="1589" type="text/json">{"id":1589,"name":"Photography","url":"https://www.academia.edu/Documents/in/Photography?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=27222378]'), work: {"id":27222378,"title":"Sensitivity and Specificity of Posterior Corneal Elevation Measured by Pentacam in Discriminating Keratoconus/Subclinical Keratoconus","created_at":"2016-07-24T09:59:12.097-07:00","url":"https://www.academia.edu/27222378/Sensitivity_and_Specificity_of_Posterior_Corneal_Elevation_Measured_by_Pentacam_in_Discriminating_Keratoconus_Subclinical_Keratoconus?f_ri=17721","dom_id":"work_27222378","summary":null,"downloadable_attachments":[{"id":47479770,"asset_id":27222378,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51306740,"first_name":"Davide","last_name":"Turco","domain_name":"independent","page_name":"DavideTurco1","display_name":"Davide Turco","profile_url":"https://independent.academia.edu/DavideTurco1?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false},{"id":1589,"name":"Photography","url":"https://www.academia.edu/Documents/in/Photography?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721"},{"id":96574,"name":"Keratoconus","url":"https://www.academia.edu/Documents/in/Keratoconus?f_ri=17721"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":194916,"name":"ROC Curve","url":"https://www.academia.edu/Documents/in/ROC_Curve?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=17721"},{"id":401947,"name":"Sensitivity","url":"https://www.academia.edu/Documents/in/Sensitivity?f_ri=17721"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=17721"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=17721"},{"id":1161531,"name":"Corneal topography","url":"https://www.academia.edu/Documents/in/Corneal_topography?f_ri=17721"},{"id":1191613,"name":"Likelihood Functions","url":"https://www.academia.edu/Documents/in/Likelihood_Functions?f_ri=17721"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=17721"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_73220811" data-work_id="73220811" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/73220811/Central_and_peripheral_corneal_thickness_measurement_with_Orbscan_II_and_topographical_ultrasound_pachymetry">Central and peripheral corneal thickness measurement with Orbscan II and topographical ultrasound pachymetry</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: To compare thickness measurements of the central 6.0 mm of the cornea obtained with the Orbscan® II topography system and topographical ultrasound pachymetry. Setting: School of Optometry, University of Santiago de Compostela,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_73220811" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: To compare thickness measurements of the central 6.0 mm of the cornea obtained with the Orbscan® II topography system and topographical ultrasound pachymetry. Setting: School of Optometry, University of Santiago de Compostela, Galicia, Spain. Methods: In 24 right eyes, pachymetric measurements were taken at the center and 1.2 mm and 3.0 mm on the superior and inferior hemimeridians. A 1‐sample t test was applied to assess the significance of the relationship between Orbscan II and ultrasound methods. The relationship between the 2 was assessed by analyzing regression and plotting the differences against the mean corneal thickness. Orbscan II data were analyzed in 3 ways: (1) without the application of an acoustic equivalent correction factor; (2) with a correction factor of 0.92, as recommended by the manufacturer; (3) with correction using the equations derived in this study. The data were systematically compared with those of ultrasound pachymetry. Results: Before the cor...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/73220811" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9460c25cb2ec4546927287ebb8fb2297" rel="nofollow" data-download="{"attachment_id":81826098,"asset_id":73220811,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81826098/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="27344297" href="https://independent.academia.edu/MasudiA">Ali Masudi</a><script data-card-contents-for-user="27344297" type="text/json">{"id":27344297,"first_name":"Ali","last_name":"Masudi","domain_name":"independent","page_name":"MasudiA","display_name":"Ali Masudi","profile_url":"https://independent.academia.edu/MasudiA?f_ri=17721","photo":"https://0.academia-photos.com/27344297/75149442/63656112/s65_ali.masudi.png"}</script></span></span></li><li class="js-paper-rank-work_73220811 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="73220811"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 73220811, container: ".js-paper-rank-work_73220811", }); 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Setting: School of Optometry, University of Santiago de Compostela, Galicia, Spain. Methods: In 24 right eyes, pachymetric measurements were taken at the center and 1.2 mm and 3.0 mm on the superior and inferior hemimeridians. A 1‐sample t test was applied to assess the significance of the relationship between Orbscan II and ultrasound methods. The relationship between the 2 was assessed by analyzing regression and plotting the differences against the mean corneal thickness. Orbscan II data were analyzed in 3 ways: (1) without the application of an acoustic equivalent correction factor; (2) with a correction factor of 0.92, as recommended by the manufacturer; (3) with correction using the equations derived in this study. The data were systematically compared with those of ultrasound pachymetry. 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Discussion</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/54365478" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6a4af58108322faec36f82ac6bf66c0c" rel="nofollow" data-download="{"attachment_id":70770390,"asset_id":54365478,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/70770390/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39360923" href="https://independent.academia.edu/DouglasKoch2">Douglas Koch</a><script data-card-contents-for-user="39360923" type="text/json">{"id":39360923,"first_name":"Douglas","last_name":"Koch","domain_name":"independent","page_name":"DouglasKoch2","display_name":"Douglas Koch","profile_url":"https://independent.academia.edu/DouglasKoch2?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_54365478 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="54365478"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 54365478, container: ".js-paper-rank-work_54365478", }); 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Meth-ods: All cases diagnosed with Acanthamoeba keratitis in a referral centre from June 1994 through June 1997 were included.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13182180" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: To describe the outcome of a series of Acanthamoeba keratitis treated with a similar regimen. Meth-ods: All cases diagnosed with Acanthamoeba keratitis in a referral centre from June 1994 through June 1997 were included. Diagnosis of Acanthamoeba keratitis was ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13182180" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8fad17904b58f81109a69d11d61b4ca0" rel="nofollow" data-download="{"attachment_id":45679738,"asset_id":13182180,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45679738/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32438782" href="https://independent.academia.edu/MushtaqHussain14">Mushtaq Hussain</a><script data-card-contents-for-user="32438782" type="text/json">{"id":32438782,"first_name":"Mushtaq","last_name":"Hussain","domain_name":"independent","page_name":"MushtaqHussain14","display_name":"Mushtaq Hussain","profile_url":"https://independent.academia.edu/MushtaqHussain14?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13182180 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13182180"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13182180, container: ".js-paper-rank-work_13182180", }); 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Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48447912" data-work_id="48447912" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48447912/Integration_of_Scheimpflug_Based_Corneal_Tomography_and_Biomechanical_Assessments_for_Enhancing_Ectasia_Detection">Integration of Scheimpflug-Based Corneal Tomography and Biomechanical Assessments for Enhancing Ectasia Detection</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">To present the Tomographic and Biomechanical Index (TBI), which combines Scheimpflugbased corneal tomography and biomechanics for enhancing ectasia detection. Patients from different continents were retrospectively studied. The normal... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48447912" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To present the Tomographic and Biomechanical Index (TBI), which combines Scheimpflugbased corneal tomography and biomechanics for enhancing ectasia detection. Patients from different continents were retrospectively studied. The normal group included 1 eye randomly selected from 480 patients with normal corneas and the keratoconus group included 1 eye randomly selected from 204 patients with keratoconus. There were two groups: 72 ectatic eyes with no surgery from 94 patients with very asymmetric ectasia (VAE-E group) and the fellow eyes of these patients with normal topography (VAE-NT group). Pentacam HR and Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) parameters were analyzed and combined using different artificial intelligence methods. The accuracies for detecting ectasia of the Belin/Ambrósio Deviation (BAD-D) and Corvis Biomechanical Index (CBI) were compared to the TBI, considering the areas under receiver operating characteristic curves (AUROCs). The random forest meth...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48447912" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="28d9cfbe116c297716e6ab30dd4adfcd" rel="nofollow" data-download="{"attachment_id":67054218,"asset_id":48447912,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67054218/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39243268" href="https://independent.academia.edu/RenatoAmbr%C3%B3sio">Renato Ambrósio</a><script data-card-contents-for-user="39243268" type="text/json">{"id":39243268,"first_name":"Renato","last_name":"Ambrósio","domain_name":"independent","page_name":"RenatoAmbrósio","display_name":"Renato Ambrósio","profile_url":"https://independent.academia.edu/RenatoAmbr%C3%B3sio?f_ri=17721","photo":"https://0.academia-photos.com/39243268/89535042/78250698/s65_renato.ambr_sio.jpeg"}</script></span></span></li><li class="js-paper-rank-work_48447912 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48447912"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48447912, container: ".js-paper-rank-work_48447912", }); 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Patients from different continents were retrospectively studied. The normal group included 1 eye randomly selected from 480 patients with normal corneas and the keratoconus group included 1 eye randomly selected from 204 patients with keratoconus. There were two groups: 72 ectatic eyes with no surgery from 94 patients with very asymmetric ectasia (VAE-E group) and the fellow eyes of these patients with normal topography (VAE-NT group). Pentacam HR and Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) parameters were analyzed and combined using different artificial intelligence methods. The accuracies for detecting ectasia of the Belin/Ambrósio Deviation (BAD-D) and Corvis Biomechanical Index (CBI) were compared to the TBI, considering the areas under receiver operating characteristic curves (AUROCs). The random forest meth...","downloadable_attachments":[{"id":67054218,"asset_id":48447912,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39243268,"first_name":"Renato","last_name":"Ambrósio","domain_name":"independent","page_name":"RenatoAmbrósio","display_name":"Renato Ambrósio","profile_url":"https://independent.academia.edu/RenatoAmbr%C3%B3sio?f_ri=17721","photo":"https://0.academia-photos.com/39243268/89535042/78250698/s65_renato.ambr_sio.jpeg"}],"research_interests":[{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=17721","nofollow":false},{"id":43860,"name":"Refractive Surgery","url":"https://www.academia.edu/Documents/in/Refractive_Surgery?f_ri=17721","nofollow":false},{"id":48904,"name":"Elasticity","url":"https://www.academia.edu/Documents/in/Elasticity?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=17721"},{"id":96574,"name":"Keratoconus","url":"https://www.academia.edu/Documents/in/Keratoconus?f_ri=17721"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=17721"},{"id":194916,"name":"ROC Curve","url":"https://www.academia.edu/Documents/in/ROC_Curve?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=17721"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=17721"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=17721"},{"id":878239,"name":"Corneal Pachymetry","url":"https://www.academia.edu/Documents/in/Corneal_Pachymetry?f_ri=17721"},{"id":1161531,"name":"Corneal topography","url":"https://www.academia.edu/Documents/in/Corneal_topography?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_31380434" data-work_id="31380434" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/31380434/_Antibiotic_susceptibility_patterns_of_bacteria_isolated_from_keratitis_and_intraocular_infections_at_Fundaci%C3%B3n_Oftalmol%C3%B3gica_de_Santander_FOSCAL_Floridablanca_Colombia_">[Antibiotic susceptibility patterns of bacteria isolated from keratitis and intraocular infections at Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Colombia]</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Bacterial resistance is critical for the selection of antibiotics in the treatment of infections, so it is vital to know its current status in our geographical area. To determine in vitro antibiotic susceptibility of bacterial isolates... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_31380434" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Bacterial resistance is critical for the selection of antibiotics in the treatment of infections, so it is vital to know its current status in our geographical area. To determine in vitro antibiotic susceptibility of bacterial isolates obtained from keratitis and intraocular infections. A retrospective study of microbiological tests in Fundación Oftalmológica de Santander (FOSCAL) was carried out between June, 2011, and January, 2012. A total of 92 samples were examined and 110 bacteria, 27 fungi and 12 free-living amoebae were identified. Polymicrobial infections constituted 50% of the total; 1.1%, 0%, 1.1%, 16.9%, 29.3% and 85% of Gram-positive bacteria were resistant to imipenem, moxifloxacin, gatifloxacin, levofloxacin, ciprofloxacin and tobramycin, respectively, while 0%, 8.3%, 0%, 0%, 18.2% and 27.3% of Gram-negative bacteria were resistant to imipenem, moxifloxacin, gatifloxacin, levofloxacin, ciprofloxacin and tobramycin, respectively. For methicillin-resistant coagulase-pos...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/31380434" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="27d15ec90abe10eb92b72934b5a38f2e" rel="nofollow" data-download="{"attachment_id":51756350,"asset_id":31380434,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51756350/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36051745" href="https://independent.academia.edu/SrikantaChowdhury">Srikanta Chowdhury</a><script data-card-contents-for-user="36051745" type="text/json">{"id":36051745,"first_name":"Srikanta","last_name":"Chowdhury","domain_name":"independent","page_name":"SrikantaChowdhury","display_name":"Srikanta Chowdhury","profile_url":"https://independent.academia.edu/SrikantaChowdhury?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_31380434 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="31380434"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 31380434, container: ".js-paper-rank-work_31380434", }); 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To determine in vitro antibiotic susceptibility of bacterial isolates obtained from keratitis and intraocular infections. A retrospective study of microbiological tests in Fundación Oftalmológica de Santander (FOSCAL) was carried out between June, 2011, and January, 2012. A total of 92 samples were examined and 110 bacteria, 27 fungi and 12 free-living amoebae were identified. Polymicrobial infections constituted 50% of the total; 1.1%, 0%, 1.1%, 16.9%, 29.3% and 85% of Gram-positive bacteria were resistant to imipenem, moxifloxacin, gatifloxacin, levofloxacin, ciprofloxacin and tobramycin, respectively, while 0%, 8.3%, 0%, 0%, 18.2% and 27.3% of Gram-negative bacteria were resistant to imipenem, moxifloxacin, gatifloxacin, levofloxacin, ciprofloxacin and tobramycin, respectively. 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href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6791" href="https://www.academia.edu/Documents/in/Aging">Aging</a>, <script data-card-contents-for-ri="6791" type="text/json">{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22722088]'), work: {"id":22722088,"title":"Age-related changes in optical and biometric characteristics of emmetropic eyes","created_at":"2016-03-02T20:50:15.387-08:00","url":"https://www.academia.edu/22722088/Age_related_changes_in_optical_and_biometric_characteristics_of_emmetropic_eyes?f_ri=17721","dom_id":"work_22722088","summary":null,"downloadable_attachments":[{"id":43292745,"asset_id":22722088,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44353339,"first_name":"James","last_name":"Pope","domain_name":"qut","page_name":"JamesPope","display_name":"James M 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Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=17721"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=17721"},{"id":413192,"name":"Sex Factors","url":"https://www.academia.edu/Documents/in/Sex_Factors?f_ri=17721"},{"id":1161531,"name":"Corneal topography","url":"https://www.academia.edu/Documents/in/Corneal_topography?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17069958 coauthored" data-work_id="17069958" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17069958/Clinical_Efficacy_of_Moxifloxacin_in_the_Treatment_of_Bacterial_Keratitis">Clinical Efficacy of Moxifloxacin in the Treatment of Bacterial Keratitis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">To determine the clinical efficacy and safety of moxifloxacin (1.0%) in patients with bacterial keratitis compared with patients treated with ofloxacin (0.3%) or fortified tobramycin (1.33%)/cephazolin (5%). Prospective randomized trial.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_17069958" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To determine the clinical efficacy and safety of moxifloxacin (1.0%) in patients with bacterial keratitis compared with patients treated with ofloxacin (0.3%) or fortified tobramycin (1.33%)/cephazolin (5%). Prospective randomized trial. A total of 229 patients diagnosed with bacterial keratitis were enrolled in the study; 78 patients were randomized to the fortified tobramycin/cephazolin group, 77 patients to the moxifloxacin group, and 74 patients to the ofloxacin group. A total of 225 patients were evaluable for safety and 198 patients were included in the efficacy analysis. After corneal specimens were obtained, the assigned study medication was instilled every hour, day and night, for 48 hours and on the third day, every hour by day and every 2 hours at night. For days 4 and 5, 1 drop every 2 hours by day and every 4 hours at night, and for days 6 and 7, 1 drop every 4 hours. After day 7, the antibiotic was tapered to every 6 hours and stopped when appropriate. Resolution of keratitis and healing of ulcer, time to cure, mean time to discharge, clinical sign score, adverse reactions to study medication, and treatment failures. Of the 186 nonexiting patients, resolution of the keratitis and healing of the ulcer occurred in 175 (94%) nonexiting patients. In the 175 patients in whom the corneal ulcer was cured, there were no statistically significant differences between the treatment groups for the mean time to cure (P = 0.25). There were no statistically significant differences between the 3 treatment groups in the various sign parameters including the sign score. A positive bacterial corneal culture was obtained in 190 (83%) of the 229 enrolled patients. The distribution of the species of bacterial organisms was similar in each treatment group and no significant difference in the percentage of isolates between the groups was observed. Twelve (5.2%) of the treated patients had serious complications (perforation or enucleation). No serious events attributable to therapy occurred during the study and all treatments were safe and well tolerated. No difference in healing rate, cure rate, or complications between fortified cephazolin and tobramycin, ofloxacin, or moxifloxacin was seen in this study.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17069958" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5237895a00675fa2f4ec882cd07387e0" rel="nofollow" data-download="{"attachment_id":42333306,"asset_id":17069958,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42333306/download_file?st=MTczMjQ3NzUwMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32547181" href="https://unimelb.academia.edu/MarkDaniell">Mark Daniell</a><script data-card-contents-for-user="32547181" type="text/json">{"id":32547181,"first_name":"Mark","last_name":"Daniell","domain_name":"unimelb","page_name":"MarkDaniell","display_name":"Mark Daniell","profile_url":"https://unimelb.academia.edu/MarkDaniell?f_ri=17721","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-17069958">+1</span><div class="hidden js-additional-users-17069958"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://unimelb.academia.edu/GrantSnibson">Grant Snibson</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-17069958'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-17069958').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_17069958 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="17069958"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17069958; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17069958]").text(description); $(".js-view-count-work_17069958").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_17069958").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="17069958"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="627" href="https://www.academia.edu/Documents/in/Ophthalmology">Ophthalmology</a>, <script data-card-contents-for-ri="627" type="text/json">{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17721" href="https://www.academia.edu/Documents/in/Cornea">Cornea</a>, <script data-card-contents-for-ri="17721" type="text/json">{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17069958]'), work: {"id":17069958,"title":"Clinical Efficacy of Moxifloxacin in the Treatment of Bacterial Keratitis","created_at":"2015-10-20T16:11:43.437-07:00","url":"https://www.academia.edu/17069958/Clinical_Efficacy_of_Moxifloxacin_in_the_Treatment_of_Bacterial_Keratitis?f_ri=17721","dom_id":"work_17069958","summary":"To determine the clinical efficacy and safety of moxifloxacin (1.0%) in patients with bacterial keratitis compared with patients treated with ofloxacin (0.3%) or fortified tobramycin (1.33%)/cephazolin (5%). Prospective randomized trial. A total of 229 patients diagnosed with bacterial keratitis were enrolled in the study; 78 patients were randomized to the fortified tobramycin/cephazolin group, 77 patients to the moxifloxacin group, and 74 patients to the ofloxacin group. A total of 225 patients were evaluable for safety and 198 patients were included in the efficacy analysis. After corneal specimens were obtained, the assigned study medication was instilled every hour, day and night, for 48 hours and on the third day, every hour by day and every 2 hours at night. For days 4 and 5, 1 drop every 2 hours by day and every 4 hours at night, and for days 6 and 7, 1 drop every 4 hours. After day 7, the antibiotic was tapered to every 6 hours and stopped when appropriate. Resolution of keratitis and healing of ulcer, time to cure, mean time to discharge, clinical sign score, adverse reactions to study medication, and treatment failures. Of the 186 nonexiting patients, resolution of the keratitis and healing of the ulcer occurred in 175 (94%) nonexiting patients. In the 175 patients in whom the corneal ulcer was cured, there were no statistically significant differences between the treatment groups for the mean time to cure (P = 0.25). There were no statistically significant differences between the 3 treatment groups in the various sign parameters including the sign score. A positive bacterial corneal culture was obtained in 190 (83%) of the 229 enrolled patients. The distribution of the species of bacterial organisms was similar in each treatment group and no significant difference in the percentage of isolates between the groups was observed. Twelve (5.2%) of the treated patients had serious complications (perforation or enucleation). No serious events attributable to therapy occurred during the study and all treatments were safe and well tolerated. No difference in healing rate, cure rate, or complications between fortified cephazolin and tobramycin, ofloxacin, or moxifloxacin was seen in this study.","downloadable_attachments":[{"id":42333306,"asset_id":17069958,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32547181,"first_name":"Mark","last_name":"Daniell","domain_name":"unimelb","page_name":"MarkDaniell","display_name":"Mark Daniell","profile_url":"https://unimelb.academia.edu/MarkDaniell?f_ri=17721","photo":"/images/s65_no_pic.png"},{"id":36632723,"first_name":"Grant","last_name":"Snibson","domain_name":"unimelb","page_name":"GrantSnibson","display_name":"Grant Snibson","profile_url":"https://unimelb.academia.edu/GrantSnibson?f_ri=17721","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=17721","nofollow":false},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=17721"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=17721"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":113903,"name":"Bacteria","url":"https://www.academia.edu/Documents/in/Bacteria?f_ri=17721"},{"id":175778,"name":"Corneal Ulcer Management","url":"https://www.academia.edu/Documents/in/Corneal_Ulcer_Management?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=17721"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=17721"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=17721"},{"id":572282,"name":"Combination drug therapy","url":"https://www.academia.edu/Documents/in/Combination_drug_therapy?f_ri=17721"},{"id":816974,"name":"Quinolines","url":"https://www.academia.edu/Documents/in/Quinolines?f_ri=17721"},{"id":893767,"name":"Ofloxacin","url":"https://www.academia.edu/Documents/in/Ofloxacin?f_ri=17721"},{"id":1552428,"name":"Fluoroquinolones","url":"https://www.academia.edu/Documents/in/Fluoroquinolones?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_78296598" data-work_id="78296598" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/78296598/Effect_of_corneal_collagen_crosslinking_on_corneal_sensitivity_tear_function_and_innervation_a_clinical_and_confocal_microscopic_study">Effect of corneal collagen crosslinking on corneal sensitivity, tear function and innervation: a clinical and confocal microscopic study</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/78296598" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="baf016851611097d5e5ad976d5fec697" rel="nofollow" data-download="{"attachment_id":85393561,"asset_id":78296598,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" 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href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=17721","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a><script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=78296598]'), work: {"id":78296598,"title":"Effect of corneal collagen crosslinking on corneal sensitivity, tear function and innervation: a clinical and confocal microscopic study","created_at":"2022-05-03T00:39:32.812-07:00","url":"https://www.academia.edu/78296598/Effect_of_corneal_collagen_crosslinking_on_corneal_sensitivity_tear_function_and_innervation_a_clinical_and_confocal_microscopic_study?f_ri=17721","dom_id":"work_78296598","summary":null,"downloadable_attachments":[{"id":85393561,"asset_id":78296598,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36803452,"first_name":"Ioannis","last_name":"Pallikaris","domain_name":"independent","page_name":"IPallikaris","display_name":"Ioannis Pallikaris","profile_url":"https://independent.academia.edu/IPallikaris?f_ri=17721","photo":"https://0.academia-photos.com/36803452/102475423/91642168/s65_ioannis.pallikaris.jpeg"}],"research_interests":[{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=17721","nofollow":false},{"id":17721,"name":"Cornea","url":"https://www.academia.edu/Documents/in/Cornea?f_ri=17721","nofollow":false},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=17721","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=17721","nofollow":false},{"id":96574,"name":"Keratoconus","url":"https://www.academia.edu/Documents/in/Keratoconus?f_ri=17721"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=17721"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=17721"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=17721"},{"id":228471,"name":"Tears","url":"https://www.academia.edu/Documents/in/Tears?f_ri=17721"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=17721"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=17721"},{"id":375077,"name":"Photochemotherapy","url":"https://www.academia.edu/Documents/in/Photochemotherapy?f_ri=17721"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=17721"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=17721"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=17721"},{"id":1573017,"name":"Riboflavin","url":"https://www.academia.edu/Documents/in/Riboflavin?f_ri=17721"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48447852" data-work_id="48447852" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48447852/Corneal_cells_chatty_in_development_homeostasis_wound_healing_and_disease">Corneal cells: chatty in development, homeostasis,wound healing, and disease</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li 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