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class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="24138850" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/24138850/Prevention_of_Corneal_Neovascularization_Comparison_of_Different_Doses_of_Subconjunctival_Bevacizumab_with_Its_Topical_Form_in_Experimental_Rats">Prevention of Corneal Neovascularization: Comparison of Different Doses of Subconjunctival Bevacizumab with Its Topical Form in Experimental Rats</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="46559123" href="https://independent.academia.edu/MaryamTahvildari">Maryam Tahvildari</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Ophthalmic Research, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline 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data-entity-id="93827717" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/93827717/Effects_of_topical_and_subconjunctival_use_of_bevacizumab_on_corneal_neovascularization_in_rabbits_eyes">Effects of topical and subconjunctival use of bevacizumab on corneal neovascularization in rabbits' eyes</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="44720896" href="https://independent.academia.edu/AnaPaulaMiyaguskoTabaOguido">Ana Paula Miyagusko Taba Oguido</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Arquivos brasileiros de oftalmologia</p><p class="ds-related-work--abstract ds2-5-body-sm">To evaluate and compare the effects of topical application and subconjunctival injection of bevacizumab on corneal neovascularization (CNV) in rabbits&#39; eyes after chemical burning of the cornea. The animals were randomly distributed into four groups of five animals. In one group, the drug was instilled, while in another, it was administered by subconjunctival injection. The two procedures using bevacizumab were compared with instillation and subconjunctival injection of saline solution (S). Neovascularization was evaluated according to the size of the invasion area of new blood vessels and through computerized analysis of this area. The data were analyzed using the Kruskal-Wallis test followed by Dunn&#39;s test for two-by-two comparison of the groups, to assess the external examination of CNV. Analysis of variance was used to assess the area of CNV. P&lt;0.05 was considered statistically significant. Assessing both the external examination and the invasion area of neovessels on...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Effects of topical and subconjunctival use of bevacizumab on corneal neovascularization in rabbits' eyes","attachmentId":96457479,"attachmentType":"pdf","work_url":"https://www.academia.edu/93827717/Effects_of_topical_and_subconjunctival_use_of_bevacizumab_on_corneal_neovascularization_in_rabbits_eyes","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/93827717/Effects_of_topical_and_subconjunctival_use_of_bevacizumab_on_corneal_neovascularization_in_rabbits_eyes"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="80417418" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/80417418/Comparison_of_the_inhibitory_effect_of_different_doses_of_subconjunctival_bevacizumab_application_in_an_experimental_model_of_corneal_neovascularization">Comparison of the inhibitory effect of different doses of subconjunctival bevacizumab application in an experimental model of corneal neovascularization</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="137627803" href="https://acibadem.academia.edu/RanaAltanYayciogluMDFEBO">Rana Altan-Yaycioglu, MD, FEBO</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International journal of ophthalmology, 2018</p><p class="ds-related-work--abstract ds2-5-body-sm">AIM To evaluate the inhibitory effect of subconjunctival bevacizumab as single- and multiple-dose application, and compare their effects on corneal neovascularization in a rat model. METHODS Thirty adult Sprague-Dawley rats were used in this experimental study. The central cornea of the rats was cauterized chemically. The rats were randomly enrolled into three groups. All groups received subconjunctival injections. In Group 1 (control group, n=10), 0.05 mL 0.9% NaCl solution was injected on the first day. In Group 2 (single-dose group, n=10), 0.05 mL bevacizumab (1.25 mg) was injected on the first day. In Group 3 (multiple-dose group, n=10), four doses of 0.05 mL bevacizumab (1.25 mg) were injected on the first, third, fifth and seventh day. Slit-lamp examination of all rats was performed at the third and ninth day. Digital images of the corneas were taken and analyzed using image analysis software to calculate corneal neovascularization area. All rats were sacrificed on the tenth d...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Comparison of the inhibitory effect of different doses of subconjunctival bevacizumab application in an experimental model of corneal neovascularization","attachmentId":86806283,"attachmentType":"pdf","work_url":"https://www.academia.edu/80417418/Comparison_of_the_inhibitory_effect_of_different_doses_of_subconjunctival_bevacizumab_application_in_an_experimental_model_of_corneal_neovascularization","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/80417418/Comparison_of_the_inhibitory_effect_of_different_doses_of_subconjunctival_bevacizumab_application_in_an_experimental_model_of_corneal_neovascularization"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="9664095" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/9664095/Inhibition_of_Corneal_Neovascularization_by_Topical_Bevacizumab_Anti_VEGF_and_Sunitinib_Anti_VEGF_and_Anti_PDGF_in_an_Animal_Model">Inhibition of Corneal Neovascularization by Topical Bevacizumab (Anti-VEGF) and Sunitinib (Anti-VEGF and Anti-PDGF) in an Animal Model</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="23083462" href="https://unsa-pe.academia.edu/JMiguelMollo">J Miguel Mollo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">American Journal of Ophthalmology, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Inhibition of Corneal Neovascularization by Topical Bevacizumab (Anti-VEGF) and Sunitinib (Anti-VEGF and Anti-PDGF) in an Animal Model","attachmentId":47683605,"attachmentType":"pdf","work_url":"https://www.academia.edu/9664095/Inhibition_of_Corneal_Neovascularization_by_Topical_Bevacizumab_Anti_VEGF_and_Sunitinib_Anti_VEGF_and_Anti_PDGF_in_an_Animal_Model","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/9664095/Inhibition_of_Corneal_Neovascularization_by_Topical_Bevacizumab_Anti_VEGF_and_Sunitinib_Anti_VEGF_and_Anti_PDGF_in_an_Animal_Model"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="101248790" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/101248790/Effect_of_Subconjunctival_Bevacizumab_Avastin_on_Experimental_Corneal_Neovascularization_in_Guinea_Pigs">Effect of Subconjunctival Bevacizumab (Avastin) on Experimental Corneal Neovascularization in Guinea Pigs</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="268348580" href="https://independent.academia.edu/AliDurukan3">Ali Durukan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Cornea, 2008</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Effect of Subconjunctival Bevacizumab (Avastin) on Experimental Corneal Neovascularization in Guinea Pigs","attachmentId":101841919,"attachmentType":"pdf","work_url":"https://www.academia.edu/101248790/Effect_of_Subconjunctival_Bevacizumab_Avastin_on_Experimental_Corneal_Neovascularization_in_Guinea_Pigs","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/101248790/Effect_of_Subconjunctival_Bevacizumab_Avastin_on_Experimental_Corneal_Neovascularization_in_Guinea_Pigs"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="73026747" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/73026747/The_Effect_of_Topical_Bevacizumab_on_Corneal_Neovasularization_in_a_Rabbit_Model">The Effect of Topical Bevacizumab on Corneal Neovasularization in a Rabbit Model</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="55060323" href="https://independent.academia.edu/kasiriali">ali kasiri</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2017</p><p class="ds-related-work--abstract ds2-5-body-sm">Objectives: To evaluate the effect of topical bevacizumab for treatment of the corneal neovascularization (CNV) in a rabbit model of corneal injury. Methods: Corneal neovascularization was induced by 3 sutures of the cornea in 20 rabbits (20 corneas). Two weeks later all sutures have been removed then rabbits were divided randomly into 2 groups: group 1 received topical bevacizumab at 10 mg/mL and group 2 received only topical normal salin drops as control group, in the right eyes three times a day for two weeks. Photographs of (CNV) were obtained before drug administration and at 1 and 2 weeks after therapy. The images were analyzed using NIH Image J 1.49c software. Results: The mean percentage of CNV area estimated as 100 % before treatment. At the 1 week after treatment, the mean percentage of neovascularization area in Bevacizumab and Salin group were 75.64±4.32 and 93.33±4.57 respectively. Also at the 2 week after treatment were 61.45±6.18 and 84.96±5.21 respectively. After one...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The Effect of Topical Bevacizumab on Corneal Neovasularization in a Rabbit Model","attachmentId":81712638,"attachmentType":"pdf","work_url":"https://www.academia.edu/73026747/The_Effect_of_Topical_Bevacizumab_on_Corneal_Neovasularization_in_a_Rabbit_Model","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/73026747/The_Effect_of_Topical_Bevacizumab_on_Corneal_Neovasularization_in_a_Rabbit_Model"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="26902173" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26902173/The_effect_of_subconjunctival_bevacizumab_on_corneal_neovascularization_inflammation_and_re_epithelization_in_a_rabbit_model">The effect of subconjunctival bevacizumab on corneal neovascularization, inflammation and re-epithelization in a rabbit model</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50940570" href="https://independent.academia.edu/MarcosPizzolatti">Marcos Pizzolatti</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50909179" href="https://independent.academia.edu/GlaucoMello">Glauco Mello</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinics, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The effect of subconjunctival bevacizumab on corneal neovascularization, inflammation and re-epithelization in a rabbit model","attachmentId":47166205,"attachmentType":"pdf","work_url":"https://www.academia.edu/26902173/The_effect_of_subconjunctival_bevacizumab_on_corneal_neovascularization_inflammation_and_re_epithelization_in_a_rabbit_model","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/26902173/The_effect_of_subconjunctival_bevacizumab_on_corneal_neovascularization_inflammation_and_re_epithelization_in_a_rabbit_model"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="48677250" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/48677250/Inhibition_of_Corneal_Neovascularization_by_Subconjunctival_Bevacizumab_in_an_Animal_Model">Inhibition of Corneal Neovascularization by Subconjunctival Bevacizumab in an Animal Model</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33336977" href="https://johnshopkins.academia.edu/PeterGehlbach">Peter Gehlbach</a></div><p class="ds-related-work--metadata ds2-5-body-xs">American Journal of Ophthalmology, 2008</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Inhibition of Corneal Neovascularization by Subconjunctival Bevacizumab in an Animal Model","attachmentId":67165966,"attachmentType":"pdf","work_url":"https://www.academia.edu/48677250/Inhibition_of_Corneal_Neovascularization_by_Subconjunctival_Bevacizumab_in_an_Animal_Model","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/48677250/Inhibition_of_Corneal_Neovascularization_by_Subconjunctival_Bevacizumab_in_an_Animal_Model"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="105133686" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/105133686/Can_Subconjunctival_Bevacizumab_Injection_Regress_Corneal_Neovascularization">Can Subconjunctival Bevacizumab Injection Regress Corneal Neovascularization?</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="272865182" href="https://independent.academia.edu/Zeynep%C3%96zbek19">Zeynep Özbek</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Can 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You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="76051958" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/76051958/Topical_Bevacizumab_in_the_Treatment_of_Corneal_Neovascularization">Topical Bevacizumab in the Treatment of Corneal Neovascularization</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58073595" href="https://independent.academia.edu/MDastjerdi">Mohammad Dastjerdi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Archives of Ophthalmology, 2009</p><div 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data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/103838261/Comparison_of_subconjunctivally_injected_bevacizumab_ranibizumab_and_pegaptanib_for_inhibition_of_corneal_neovascularization_in_a_rat_model">Comparison of subconjunctivally injected bevacizumab, ranibizumab, and pegaptanib for inhibition of corneal neovascularization in a rat model</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35203799" href="https://independent.academia.edu/YoncaAkova">Yonca Akova</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International journal of ophthalmology, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Comparison of subconjunctivally injected 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