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(PDF) Cytogenetic changes in subjects occupationally exposed to benzene | Karmela Sentija - Academia.edu

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translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/1545014/11_Chromosomal_Damage_Risk_Assessment_to_Benzene_Exposure"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="81194117" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/81194117/Lymphocyte_chromosome_breakage_in_low_benzene_exposure_among_Indonesian_workers">Lymphocyte chromosome breakage in low benzene exposure among Indonesian workers</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31928115" href="https://independent.academia.edu/DewiSoemarko">Dewi Soemarko</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Medical Journal of Indonesia, 2015</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: Benzene has been used in industry since long time and its level in environment should be controled. Although environmental benzene level has been controlled to less than 1 ppm, negative effect of benzene exposure is still observed, such as chromosome breakage. This study aimed to know the prevalence of lymphocyte chromosome breakage and the influencing factors among workers in low level benzene exposure.Methods: This was a cross sectional study in oil &amp; gas industry T, conducted between September 2007 and April 2010. The study subjects consisted of 115 workers from production section and head office. Data on type of work, duration of benzene exposure, and antioxidant consumption were collected by interview as well as observation of working process. Lymphocyte chromosome breakage was examined by banding method. Analysis of relationship between chromosome breakage and risk factors was performed by chi-square and odd ratio, whereas the role of determinant risk factors was a...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Lymphocyte chromosome breakage in low benzene exposure among Indonesian workers&quot;,&quot;attachmentId&quot;:87324394,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/81194117/Lymphocyte_chromosome_breakage_in_low_benzene_exposure_among_Indonesian_workers&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/81194117/Lymphocyte_chromosome_breakage_in_low_benzene_exposure_among_Indonesian_workers"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="55509377" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/55509377/Increased_translocations_and_aneusomy_in_chromosomes_8_and_21_among_workers_exposed_to_benzene">Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="66419086" href="https://independent.academia.edu/ZhangLuoping">Luoping Zhang</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Cancer research, 1998</p><p class="ds-related-work--abstract ds2-5-body-sm">Chromosome aberrations in peripheral blood lymphocytes have been used for many years to monitor human populations exposed to potential carcinogens. Recent reports have confirmed the validity of this approach by demonstrating that elevated levels of chromosome aberrations in lymphocytes are associated with subsequent increased cancer risk, especially for increased mortality from hematological malignancies including acute myeloid leukemia (AML). We postulated that this approach could be improved in two ways: (a) by detecting oncogenic disease-specific aberrations; and (b) by using chromosome painting so that many more metaphases could be analyzed. Numerical and structural aberrations in chromosomes 8 and 21 are commonly observed in AML. In the present study, we painted chromosomes 8 and 21 in lymphocyte metaphases from 43 healthy workers exposed to benzene, an established cause of AML, and from 44 matched controls. To examine dose-response relationships the workers were divided into t...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene&quot;,&quot;attachmentId&quot;:71346508,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/55509377/Increased_translocations_and_aneusomy_in_chromosomes_8_and_21_among_workers_exposed_to_benzene&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" 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ds2-5-body-sm ds2-5-body-link" data-author-id="52139982" href="https://independent.academia.edu/LanceHallberg">Lance Hallberg</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental Health Perspectives, 1996</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Measurement of DNA repair deficiency in workers exposed to benzene&quot;,&quot;attachmentId&quot;:70271680,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/53417382/Measurement_of_DNA_repair_deficiency_in_workers_exposed_to_benzene&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline 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href="https://iugaza-ps.academia.edu/FadelSharif">Fadel A Sharif</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39541345" href="https://uni-saarland.academia.edu/MohammedLaqqan">Mohammed Laqqan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">iugaza.edu.ps</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Chromosomal Aberrations in Males Occupationally Exposed to Chemical Pollutants in the Gaza Strip-Palestine&quot;,&quot;attachmentId&quot;:39924606,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/18191099/Chromosomal_Aberrations_in_Males_Occupationally_Exposed_to_Chemical_Pollutants_in_the_Gaza_Strip_Palestine&quot;,&quot;alternativeTracking&quot;:true}"><span 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href="https://www.academia.edu/123043843/Chromosome_aberration_sister_chromatid_exchange_proliferative_rate_index_and_serum_thiocyanate_concentration_in_smokers_exposed_to_low_dose_benzene">Chromosome aberration, sister‐chromatid exchange, proliferative rate index, and serum thiocyanate concentration in smokers exposed to low‐dose benzene</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="300056728" href="https://independent.academia.edu/AnnaTompa1">Anna Tompa</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental and Molecular Mutagenesis, 1994</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Chromosome aberration, sister‐chromatid exchange, proliferative rate index, and serum thiocyanate concentration in 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class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="11" data-entity-id="87401218" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/87401218/Cytogenetic_damage_in_workers_exposed_to_ethylene_oxide">Cytogenetic damage in workers exposed to ethylene oxide</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="140324773" href="https://independent.academia.edu/PiergiorgioBrovedani">Piergiorgio Brovedani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Mutation Research/Genetic Toxicology, 1984</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Cytogenetic damage in workers exposed to 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ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/72383413/Genotoxicity_of_benzene_and_its_metabolites">Genotoxicity of benzene and its metabolites</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="25724345" href="https://independent.academia.edu/PeterRoss6">Peter Ross</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Mutation research, 2004</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Genotoxicity of benzene and its metabolites&quot;,&quot;attachmentId&quot;:81330835,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/72383413/Genotoxicity_of_benzene_and_its_metabolites&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" 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class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33157745" href="https://uab.academia.edu/RicardMarcos">Ricard Marcos</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental Health Perspectives, 2002</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Sister Chromatid Exchanges and Micronuclei in Peripheral Lymphocytes of Shoe Factory Workers Exposed to Solvents&quot;,&quot;attachmentId&quot;:83521697,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/75093348/Sister_Chromatid_Exchanges_and_Micronuclei_in_Peripheral_Lymphocytes_of_Shoe_Factory_Workers_Exposed_to_Solvents&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 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class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="2307557" href="https://jamescook.academia.edu/michaelbird">michael bird</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Chemico-Biological Interactions, 2008</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice&quot;,&quot;attachmentId&quot;:42889867,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/22238897/Genotoxicity_of_intermittent_co_exposure_to_benzene_and_toluene_in_male_CD_1_mice&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span 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mixture in the tyre industry</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="44563267" href="https://independent.academia.edu/MariaSasiadek">Maria Sąsiadek</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Mutation Research Letters, 1993</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Sister-chromatid exchanges and cell-cycle kinetics in the lymphocytes of workers occupationally exposed to a chemical mixture in the tyre 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js-related-work-sidebar-card" data-collection-position="16" data-entity-id="93358072" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/93358072/Chromosome_wide_aneuploidy_study_CWAS_in_workers_exposed_to_an_established_leukemogen_benzene">Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32943985" href="https://independent.academia.edu/ClionaMcHale">Cliona McHale</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Carcinogenesis, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Chromosome-wide aneuploidy study 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data-collection-position="17" data-entity-id="84597176" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/84597176/Low_air_levels_of_benzene_Correlation_between_biomarkers_of_exposure_and_genotoxic_effects">Low air levels of benzene: Correlation between biomarkers of exposure and genotoxic effects</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="99617709" href="https://independent.academia.edu/GiovanniBattistaBartolucci">Giovanni Battista Bartolucci</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Toxicology Letters, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Low air levels of benzene: Correlation 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data-entity-id="27598179" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/27598179/Benzene_increases_aneuploidy_in_the_lymphocytes_of_exposed_workers_A_comparison_of_data_obtained_by_fluorescence_in_situ_hybridization_in_interphase_and_metaphase_cells">Benzene increases aneuploidy in the lymphocytes of exposed workers: A comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="51785298" href="https://independent.academia.edu/PremaKolachana">Prema Kolachana</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental and Molecular Mutagenesis, 1999</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" 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