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> <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 14 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-14" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">14 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A8%D9%8A%D8%BA%D9%86%D8%AA%D9%8A%D8%B1%D9%81%D9%8A%D8%B1%D9%88%D9%86_%E2%80%93_%D8%A3%D9%84%D9%81%D8%A7_%E2%80%93_2%D8%A3" title="بيغنتيرفيرون – ألفا – 2أ – Arabic" lang="ar" hreflang="ar" data-title="بيغنتيرفيرون – ألفا – 2أ" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a – Bosnian" lang="bs" hreflang="bs" data-title="Pegilirani interferon alfa-2a" data-language-autonym="Bosanski" data-language-local-name="Bosnian" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Peginterferon_%CE%B1" title="Peginterferon α – German" lang="de" hreflang="de" data-title="Peginterferon α" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Peginterf%C3%A9ron_alfa-2a" title="Peginterféron alfa-2a – French" lang="fr" hreflang="fr" data-title="Peginterféron alfa-2a" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Peginterferon_alfa-2a" title="Peginterferon alfa-2a – Indonesian" lang="id" hreflang="id" data-title="Peginterferon alfa-2a" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Peginterferon_alfa-2a" title="Peginterferon alfa-2a – Malay" lang="ms" hreflang="ms" data-title="Peginterferon alfa-2a" data-language-autonym="Bahasa Melayu" data-language-local-name="Malay" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%AA%E0%AD%87%E0%AC%9C%E0%AC%BF%E0%AC%A3%E0%AD%8D%E0%AC%9F%E0%AC%B0%E0%AC%AB%E0%AD%87%E0%AC%B0%E0%AC%A8_%E0%AC%86%E0%AC%B2%E0%AC%AB%E0%AC%BE-%E0%AD%A8%E0%AC%8F" title="ପେଜିଣ୍ଟରଫେରନ ଆଲଫା-୨ଏ – Odia" lang="or" hreflang="or" data-title="ପେଜିଣ୍ଟରଫେରନ ଆଲଫା-୨ଏ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="Odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Peginterferon_alfa-2a" title="Peginterferon alfa-2a – Polish" lang="pl" hreflang="pl" data-title="Peginterferon alfa-2a" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9F%D0%B5%D0%B3%D0%B8%D0%BB%D0%B8%D1%80%D0%BE%D0%B2%D0%B0%D0%BD%D0%BD%D1%8B%D0%B9_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B5%D1%80%D0%BE%D0%BD_%D0%B0%D0%BB%D1%8C%D1%84%D0%B0-2%D0%B0" title="Пегилированный интерферон альфа-2а – Russian" lang="ru" hreflang="ru" data-title="Пегилированный интерферон альфа-2а" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Peginterferon_alfa-2a" title="Peginterferon alfa-2a – Slovenian" lang="sl" hreflang="sl" data-title="Peginterferon alfa-2a" data-language-autonym="Slovenščina" data-language-local-name="Slovenian" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a – Serbian" lang="sr" hreflang="sr" data-title="Pegilirani interferon alfa-2a" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Pegilirani interferon alfa-2a" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9F%D0%B5%D0%B3%D1%96%D0%BB%D1%8C%D0%BE%D0%B2%D0%B0%D0%BD%D0%B8%D0%B9_%D1%96%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B5%D1%80%D0%BE%D0%BD_%D0%B0%D0%BB%D1%8C%D1%84%D0%B0-2%D0%B0" title="Пегільований інтерферон альфа-2а – Ukrainian" lang="uk" hreflang="uk" data-title="Пегільований інтерферон альфа-2а" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Peginterferon_alfa-2a" title="Peginterferon alfa-2a – Vietnamese" lang="vi" hreflang="vi" data-title="Peginterferon alfa-2a" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q420056#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div 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class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Pharmaceutical drug</div> <p class="mw-empty-elt"> </p> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Peginterferon alfa-2a">Peginterferon alfa-2a</span></caption><tbody><tr><th colspan="2" class="infobox-header" style="background:#ddd">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_nomenclature#Trade_names" title="Drug nomenclature">Trade names</a></th><td class="infobox-data">Pegasys, others</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/American_Society_of_Health-System_Pharmacists" title="American Society of Health-System Pharmacists">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data"><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/ppa/peginterferon-alfa-2a.html">Professional Drug Facts</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></th><td class="infobox-data"><span title="medlineplus.gov"><a rel="nofollow" class="external text" href="https://medlineplus.gov/druginfo/meds/a605029.html">a605029</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">License data</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"> <ul><li><small><abbr class="country-name" title="United States">US</abbr></small> <a href="/wiki/DailyMed" title="DailyMed">DailyMed</a>: <span title="dailymed.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Peginterferon_alfa-2a">Peginterferon_alfa-2a</a></span></li></ul></div> </td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Pregnancy_category" title="Pregnancy category">Pregnancy<br />category</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> B3</li> <li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Route_of_administration" title="Route of administration">Routes of<br />administration</a></th><td class="infobox-data"><a href="/wiki/Subcutaneous_injection" class="mw-redirect" title="Subcutaneous injection">Subcutaneous injection</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><a href="/wiki/ATC_code_L03" title="ATC code L03">L03AB11</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=L03AB11">WHO</a></span>) <br /><a href="/wiki/ATC_code_L03" title="ATC code L03">L03AB61</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=L03AB61">WHO</a></span>) (in combinations)</li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Legal status</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">Legal status</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> <a href="/wiki/Standard_for_the_Uniform_Scheduling_of_Medicines_and_Poisons#Schedule_4" title="Standard for the Uniform Scheduling of Medicines and Poisons">S4</a> (Prescription only)</li> <li><small><abbr class="country-name" title="United Kingdom">UK</abbr>:</small> <a href="/wiki/Prescription_drug" title="Prescription drug">POM</a> (Prescription only)</li> <li><small><abbr class="country-name" title="United States">US</abbr>:</small> <a href="/wiki/Boxed_warning" title="Boxed warning"><span style="border:thin solid black;">WARNING</span></a><sup id="cite_ref-FDA-AllBoxedWarnings_1-0" class="reference"><a href="#cite_note-FDA-AllBoxedWarnings-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>Rx-only</li> <li><small><abbr class="country-name" title="European Union">EU</abbr>:</small> Rx-only<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></li> <li>In general: ℞ (Prescription only)</li></ul></div> </td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=198153-51-4">198153-51-4</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li><li>alfa-2b: <span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=215647-85-1">215647-85-1</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB00008">DB00008</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li>none</li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/Q46947ZFE7K">Q46947ZFE7K</a></span></li><li>alfa-2b: <span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/G8RGG88B68">G8RGG88B68</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D02748">D02748</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembl/explore/compound/ChEMBL1201560">ChEMBL1201560</a></span><sup> <span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span></sup></li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Chemical_formula" title="Chemical formula">Formula</a></th><td class="infobox-data"><span title="Carbon">C</span><sub>860</sub><span title="Hydrogen">H</span><sub>1353</sub><span title="Nitrogen">N</span><sub>227</sub><span title="Oxygen">O</span><sub>255</sub><span title="Sulfur">S</span><sub>9</sub></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data"><span class="nowrap"><span data-sort-value="7004192411600000000♠"></span>19<span style="margin-left:.25em;">241</span>.16</span> g·mol<sup>−1</sup></td></tr><tr><td colspan="2" class="infobox-below"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style><span class="nobold"> <sup><span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span><span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup> <a href="/wiki/Wikipedia:WikiProject_Chemicals/Chembox_validation" title="Wikipedia:WikiProject Chemicals/Chembox validation">(what is this?)</a></span><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r886047488"><span class="nobold">  <span class="reflink plainlinks nourlexpansion"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Special:ComparePages&rev1=458269040&page2=Peginterferon+alfa-2a">(verify)</a></span></span></td></tr></tbody></table> <p><b>Pegylated interferon alfa-2a</b>, sold under the brand name <b>Pegasys</b> among others, is medication used to treat <a href="/wiki/Hepatitis_C" title="Hepatitis C">hepatitis C</a> and <a href="/wiki/Hepatitis_B" title="Hepatitis B">hepatitis B</a>.<sup id="cite_ref-Pro2017_3-0" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> For hepatitis C it is typically used together with <a href="/wiki/Ribavirin" title="Ribavirin">ribavirin</a> and cure rates are between 24 and 92%.<sup id="cite_ref-Pro2017_3-1" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> For hepatitis B it may be used alone.<sup id="cite_ref-BNF69_5-0" class="reference"><a href="#cite_note-BNF69-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> It is given by <a href="/wiki/Injection_under_the_skin" class="mw-redirect" title="Injection under the skin">injection under the skin</a>.<sup id="cite_ref-Pro2017_3-2" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>Side effects are common.<sup id="cite_ref-UW2017_6-0" class="reference"><a href="#cite_note-UW2017-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> They may include headache, feeling tired, depression, trouble sleeping, hair loss, nausea, pain at the site of injection, and fever.<sup id="cite_ref-Pro2017_3-3" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Severe side effects may include <a href="/wiki/Psychosis" title="Psychosis">psychosis</a>, <a href="/wiki/Autoimmune_disorders" class="mw-redirect" title="Autoimmune disorders">autoimmune disorders</a>, <a href="/wiki/Blood_clots" class="mw-redirect" title="Blood clots">blood clots</a>, or <a href="/wiki/Infections" class="mw-redirect" title="Infections">infections</a>.<sup id="cite_ref-Pro2017_3-4" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Use with ribavirin is not recommended during <a href="/wiki/Pregnancy" title="Pregnancy">pregnancy</a>.<sup id="cite_ref-Pro2017_3-5" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Pegylated interferon alfa-2a is in the <a href="/wiki/Alpha_interferon" class="mw-redirect" title="Alpha interferon">alpha interferon</a> family of medications.<sup id="cite_ref-Pro2017_3-6" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> It is <a href="/wiki/Pegylated" class="mw-redirect" title="Pegylated">pegylated</a> to protect the molecule from breakdown.<sup id="cite_ref-UW2017_6-1" class="reference"><a href="#cite_note-UW2017-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>Pegylated interferon alfa-2a was approved for medical use in the United States in 2002.<sup id="cite_ref-Pro2017_3-7" class="reference"><a href="#cite_note-Pro2017-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> It is on the <a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">World Health Organization's List of Essential Medicines</a>.<sup id="cite_ref-WHO21st_7-0" class="reference"><a href="#cite_note-WHO21st-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Medical_uses">Medical uses</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=1" title="Edit section: Medical uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>This drug is approved around the world for the treatment of chronic <a href="/wiki/Hepatitis_C" title="Hepatitis C">hepatitis C</a> (including people with <a href="/wiki/HIV" title="HIV">HIV</a> co-infection, <a href="/wiki/Cirrhosis" title="Cirrhosis">cirrhosis</a>, 'normal' levels of <a href="/wiki/Alanine_transaminase" title="Alanine transaminase">ALT</a>) and has recently been approved (in the <a href="/wiki/European_Union" title="European Union">EU</a>, <a href="/wiki/United_States" title="United States">U.S.</a>, <a href="/wiki/China" title="China">China</a> and many other countries) for the treatment of chronic <a href="/wiki/Hepatitis_B" title="Hepatitis B">hepatitis B</a>. It is also used in the treatment of certain T-cell lymphomas, particularly <a href="/wiki/Mycosis_fungoides" title="Mycosis fungoides">mycosis fungoides</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (January 2023)">citation needed</span></a></i>]</sup> </p><p>Peginterferon alfa-2a is a long acting interferon. Interferons are <a href="/wiki/Proteins" class="mw-redirect" title="Proteins">proteins</a> released in the body in response to <a href="/wiki/Viral_infections" class="mw-redirect" title="Viral infections">viral infections</a>. <a href="/wiki/Interferon" title="Interferon">Interferons</a> are important for fighting <a href="/wiki/Viruses" class="mw-redirect" title="Viruses">viruses</a> in the body, for regulating reproduction of <a href="/wiki/Cell_(biology)" title="Cell (biology)">cells</a>, and for regulating the immune system.<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Host_genetic_factors">Host genetic factors</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=2" title="Edit section: Host genetic factors"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>For genotype 1 hepatitis C treated with pegylated interferon alfa-2a or <a href="/wiki/Peginterferon_alfa-2b" title="Peginterferon alfa-2b">pegylated interferon alfa-2b</a> combined with <a href="/wiki/Ribavirin" title="Ribavirin">ribavirin</a>, it has been shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in response to the treatment. This finding, originally reported in <i><a href="/wiki/Nature_(journal)" title="Nature (journal)">Nature</a></i>,<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> showed genotype 1 hepatitis C patients carrying certain genetic variant alleles near the IL28B gene are more likely to achieve sustained virological response after the treatment than others. Another report in Nature demonstrated the same genetic variants are also associated with the natural clearance of the genotype 1 hepatitis C virus.<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Manufacturing">Manufacturing</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=3" title="Edit section: Manufacturing"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>It is <a href="/wiki/Pegylated" class="mw-redirect" title="Pegylated">pegylated</a> with a branched 40<span class="nowrap"> </span>kg/mol PEG chain.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Society_and_culture">Society and culture</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=4" title="Edit section: Society and culture"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Availability">Availability</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=5" title="Edit section: Availability"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Peginterferon alfa-2a is manufactured under the brand name Pegasys. In 2021, <a href="/wiki/Hoffmann-La_Roche" class="mw-redirect" title="Hoffmann-La Roche">Roche Pharmaceuticals</a> sold the worldwide rights of Pegasys (excluding China and Japan) to zr pharma& GmbH (pharma&).<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Roche_HYR_2021_16-0" class="reference"><a href="#cite_note-Roche_HYR_2021-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> In May 2022, Roche Australia transferred the sales and marketing of Pegasys to Echo Therapeutics Pty Ltd.<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Research">Research</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=6" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A <a href="/wiki/Cochrane_(organisation)" title="Cochrane (organisation)">Cochrane Review</a> sought to determine whether interferon alfa-2a could be used as a treatment for individuals with <a href="/wiki/Macular_degeneration" title="Macular degeneration">neovascular age-related macular degeneration</a>. They found no evidence of improved visual acuity with potential harm.<sup id="cite_ref-Reddy_18-0" class="reference"><a href="#cite_note-Reddy-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=7" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-FDA-AllBoxedWarnings-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-FDA-AllBoxedWarnings_1-0">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802">"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)"</a>. <i>nctr-crs.fda.gov</i>. <a href="/wiki/FDA" class="mw-redirect" title="FDA">FDA</a><span class="reference-accessdate">. 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Retrieved <span class="nowrap">12 January</span> 2017</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.drugs.com&rft.atitle=Peginterferon+Alfa-2a+%28Professional+Patient+Advice%29+-+Drugs.com&rft_id=https%3A%2F%2Fwww.drugs.com%2Fppa%2Fpeginterferon-alfa-2a.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3APeginterferon+alfa-2a" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.medicines.org.uk/emc/medicine/32432">"Pegasys 135 mcg and 180 mcg solution for injection in pre-filled pen - Summary of Product Characteristics (SPC) - (eMC)"</a>. <i>www.medicines.org.uk</i>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20170113131243/https://www.medicines.org.uk/emc/medicine/32432">Archived</a> from the original on 13 January 2017<span class="reference-accessdate">. Retrieved <span class="nowrap">12 January</span> 2017</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.medicines.org.uk&rft.atitle=Pegasys+135+mcg+and+180+mcg+solution+for+injection+in+pre-filled+pen+-+Summary+of+Product+Characteristics+%28SPC%29+-+%28eMC%29&rft_id=https%3A%2F%2Fwww.medicines.org.uk%2Femc%2Fmedicine%2F32432&rfr_id=info%3Asid%2Fen.wikipedia.org%3APeginterferon+alfa-2a" class="Z3988"></span></span> </li> <li id="cite_note-BNF69-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-BNF69_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation book cs1"><i>British national formulary : BNF 69</i> (69 ed.). 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title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cochrane+Database+Syst+Rev&rft.atitle=Antiangiogenic+therapy+with+interferon+alfa+for+neovascular+age-related+macular+degeneration&rft.volume=1&rft.issue=1&rft.pages=CD005138&rft.date=2006&rft_id=info%3Adoi%2F10.1002%2F14651858.CD005138.pub2&rft_id=info%3Apmid%2F16437522&rft.aulast=Reddy&rft.aufirst=U&rft.au=Krzystolik%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3APeginterferon+alfa-2a" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Peginterferon_alfa-2a&action=edit&section=8" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1235681985">.mw-parser-output .side-box{margin:4px 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.navbox-image img{max-width:none!important}@media print{body.ns-0 .mw-parser-output .navbox{display:none!important}}</style></div><div role="navigation" class="navbox" aria-labelledby="Cell_signaling:_cytokines" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Cytokines" title="Template:Cytokines"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Cytokines" title="Template talk:Cytokines"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Cytokines" title="Special:EditPage/Template:Cytokines"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Cell_signaling:_cytokines" style="font-size:114%;margin:0 4em"><a href="/wiki/Cell_signaling" title="Cell signaling">Cell signaling</a>: <a href="/wiki/Cytokine" title="Cytokine">cytokines</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">By family</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Chemokine" title="Chemokine">Chemokine</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">CCL</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CCL1" title="CCL1">CCL1</a></li> <li><a href="/wiki/CCL2" title="CCL2">CCL2</a>/MCP1</li> <li><a href="/wiki/CCL3" title="CCL3">CCL3</a>/MIP1α</li> <li><a href="/wiki/CCL4" title="CCL4">CCL4</a>/MIP1β</li> <li><a href="/wiki/CCL5" title="CCL5">CCL5</a>/RANTES</li> <li><a href="/wiki/CCL6" title="CCL6">CCL6</a></li> <li><a href="/wiki/CCL7" title="CCL7">CCL7</a></li> <li><a href="/wiki/CCL8" title="CCL8">CCL8</a></li> <li><a href="/wiki/CCL9" title="CCL9">CCL9</a></li> <li><a href="/wiki/CCL11" title="CCL11">CCL11</a></li> <li><a href="/wiki/CCL12" title="CCL12">CCL12</a></li> <li><a href="/wiki/CCL13" title="CCL13">CCL13</a></li> <li><a href="/wiki/CCL14" title="CCL14">CCL14</a></li> <li><a href="/wiki/CCL15" title="CCL15">CCL15</a></li> <li><a href="/wiki/CCL16" title="CCL16">CCL16</a></li> <li><a href="/wiki/CCL17" title="CCL17">CCL17</a></li> <li><a href="/wiki/CCL18" title="CCL18">CCL18</a>/PARC/DCCK1/AMAC1/MIP4</li> <li><a href="/wiki/CCL19" title="CCL19">CCL19</a></li> <li><a href="/wiki/CCL20" title="CCL20">CCL20</a></li> <li><a href="/wiki/CCL21" title="CCL21">CCL21</a></li> <li><a href="/wiki/CCL22" title="CCL22">CCL22</a></li> <li><a href="/wiki/CCL23" title="CCL23">CCL23</a></li> <li><a href="/wiki/CCL24" title="CCL24">CCL24</a></li> <li><a href="/wiki/CCL25" title="CCL25">CCL25</a></li> <li><a href="/wiki/CCL26" title="CCL26">CCL26</a></li> <li><a href="/wiki/C-C_motif_chemokine_ligand_27" title="C-C motif chemokine ligand 27">CCL27</a></li> <li><a href="/wiki/CCL28" title="CCL28">CCL28</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">CXCL</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CXCL1" title="CXCL1">CXCL1</a>/KC</li> <li><a href="/wiki/CXCL2" title="CXCL2">CXCL2</a></li> <li><a href="/wiki/CXCL3" title="CXCL3">CXCL3</a></li> <li><a href="/wiki/Platelet_factor_4" title="Platelet factor 4">CXCL4</a></li> <li><a href="/wiki/CXCL5" title="CXCL5">CXCL5</a></li> <li><a href="/wiki/CXCL6" title="CXCL6">CXCL6</a></li> <li><a href="/wiki/CXCL7" title="CXCL7">CXCL7</a></li> <li><a href="/wiki/Interleukin_8" title="Interleukin 8">CXCL8/IL8</a></li> <li><a href="/wiki/CXCL9" title="CXCL9">CXCL9</a></li> <li><a href="/wiki/CXCL10" title="CXCL10">CXCL10</a></li> <li><a href="/wiki/CXCL11" title="CXCL11">CXCL11</a></li> <li><a href="/wiki/SDF-1_(biology)" class="mw-redirect" title="SDF-1 (biology)">CXCL12</a></li> <li><a href="/wiki/CXCL13" title="CXCL13">CXCL13</a></li> <li><a href="/wiki/CXCL14" title="CXCL14">CXCL14</a></li> <li><a href="/wiki/CXCL15" title="CXCL15">CXCL15</a></li> <li><a href="/wiki/CXCL16" title="CXCL16">CXCL16</a></li> <li><a href="/wiki/CXCL17" title="CXCL17">CXCL17</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">CX3CL</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CX3CL1" title="CX3CL1">CX3CL1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">XCL</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/XCL1" title="XCL1">XCL1</a></li> <li><a href="/wiki/XCL2" title="XCL2">XCL2</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tumor_necrosis_factors" class="mw-redirect" title="Tumor necrosis factors">TNF</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Tumor_necrosis_factor_alpha" class="mw-redirect" title="Tumor necrosis factor alpha">TNFA</a></li> <li><a href="/wiki/Lymphotoxin" title="Lymphotoxin">Lymphotoxin</a> <ul><li><a href="/wiki/Lymphotoxin_alpha" title="Lymphotoxin alpha">TNFB/LTA</a></li> <li><a href="/wiki/Lymphotoxin_beta" title="Lymphotoxin beta">TNFC/LTB</a></li></ul></li> <li><a href="/wiki/OX40L" class="mw-redirect" title="OX40L">TNFSF4</a></li> <li><a href="/wiki/CD154" title="CD154">TNFSF5/CD40LG</a></li> <li><a href="/wiki/Fas_ligand" title="Fas ligand">TNFSF6</a></li> <li><a href="/wiki/CD70" title="CD70">TNFSF7</a></li> <li><a href="/wiki/CD153" title="CD153">TNFSF8</a></li> <li><a href="/wiki/4-1BB_ligand" class="mw-redirect" title="4-1BB ligand">TNFSF9</a></li> <li><a href="/wiki/TRAIL" title="TRAIL">TNFSF10</a></li> <li><a href="/wiki/RANKL" title="RANKL">TNFSF11</a></li> <li><a href="/wiki/A_proliferation-inducing_ligand" class="mw-redirect" title="A proliferation-inducing ligand">TNFSF13</a></li> <li><a href="/wiki/B-cell_activating_factor" title="B-cell activating factor">TNFSF13B</a></li> <li><a href="/wiki/EDA_(gene)" class="mw-redirect" title="EDA (gene)">EDA</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interleukin" title="Interleukin">Interleukin</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Type_I_cytokine_receptor" title="Type I cytokine receptor">Type I</a><br />(grouped by<br />receptor<br />subunit)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Common_gamma_chain" title="Common gamma chain">γ chain</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_2" title="Interleukin 2">IL2</a>/<a href="/wiki/Interleukin_15" title="Interleukin 15">IL15</a></li> <li><a href="/wiki/Interleukin_4" title="Interleukin 4">IL4</a>/<a href="/wiki/Interleukin_13" title="Interleukin 13">IL13</a></li> <li><a href="/wiki/Interleukin_7" title="Interleukin 7">IL7</a></li> <li><a href="/wiki/Interleukin_9" title="Interleukin 9">IL9</a></li> <li><a href="/wiki/Interleukin_21" title="Interleukin 21">IL21</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/CSF2RB" title="CSF2RB">β chain</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_3" title="Interleukin 3">IL3</a></li> <li><a href="/wiki/Interleukin_5" title="Interleukin 5">IL5</a></li> <li><a href="/wiki/Granulocyte_macrophage_colony-stimulating_factor" class="mw-redirect" title="Granulocyte macrophage colony-stimulating factor">GMCSF</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">IL6 like/<a href="/wiki/Glycoprotein_130" title="Glycoprotein 130">gp130</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_6" title="Interleukin 6">IL6</a></li> <li><a href="/wiki/Interleukin_11" title="Interleukin 11">IL11</a></li> <li><a href="/wiki/Interleukin_27" title="Interleukin 27">IL27</a></li> <li><a href="/wiki/Interleukin_30" title="Interleukin 30">IL30</a></li> <li><a href="/wiki/Interleukin_31" title="Interleukin 31">IL31</a> <ul><li>+non IL <a href="/wiki/Oncostatin_M" title="Oncostatin M">OSM</a></li> <li><a href="/wiki/Leukemia_inhibitory_factor" title="Leukemia inhibitory factor">LIF</a></li> <li><a href="/wiki/Ciliary_neurotrophic_factor" title="Ciliary neurotrophic factor">CNTF</a></li> <li><a href="/wiki/Cardiotrophin_1" title="Cardiotrophin 1">CTF1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/w/index.php?title=IL12_family&action=edit&redlink=1" class="new" title="IL12 family (page does not exist)">IL12 family</a>/<a href="/wiki/Interleukin_12_receptor,_beta_1_subunit" title="Interleukin 12 receptor, beta 1 subunit">IL12RB1</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_12" title="Interleukin 12">IL12</a></li> <li><a href="/wiki/Interleukin_23" title="Interleukin 23">IL23</a></li> <li><a href="/wiki/Interleukin_27" title="Interleukin 27">IL27</a></li> <li><a href="/wiki/Interleukin_35" title="Interleukin 35">IL35</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Alpha-taxilin" title="Alpha-taxilin">IL14</a></li> <li><a href="/wiki/Interleukin_16" title="Interleukin 16">IL16</a></li> <li><a href="/wiki/Interleukin_32" title="Interleukin 32">IL32</a></li> <li><a href="/wiki/Interleukin_34" title="Interleukin 34">IL34</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Type_II_cytokine_receptor" title="Type II cytokine receptor">Type II</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/IL10_family" class="mw-redirect" title="IL10 family">IL10 family</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_10" title="Interleukin 10">IL10</a>/<a href="/wiki/Interleukin_22" title="Interleukin 22">IL22</a></li> <li><a href="/wiki/Interleukin_19" title="Interleukin 19">IL19</a></li> <li><a href="/wiki/Interleukin_20" title="Interleukin 20">IL20</a></li> <li><a href="/wiki/Interleukin_24" title="Interleukin 24">IL24</a></li> <li><a href="/wiki/Interleukin_26" title="Interleukin 26">IL26</a></li> <li><a href="/wiki/Interferon_type_III" title="Interferon type III">Interferon type III</a> <ul><li><a href="/wiki/Interleukin_28" title="Interleukin 28">IL28/IFNL2+3</a></li> <li><a href="/wiki/Interleukin_29" title="Interleukin 29">IL29/IFNL1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interferon" title="Interferon">Interferon</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interferon_type_I" title="Interferon type I">I</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interferon_alpha_1" class="mw-redirect" title="Interferon alpha 1">IFNA1</a></li> <li><a href="/wiki/IFNA2" title="IFNA2">IFNA2</a></li> <li><a href="/wiki/IFNA4" title="IFNA4">IFNA4</a></li> <li><a href="/wiki/IFNA5" title="IFNA5">IFNA5</a></li> <li><a href="/wiki/IFNA6" title="IFNA6">IFNA6</a></li> <li><a href="/wiki/IFNA7" title="IFNA7">IFNA7</a></li> <li><a href="/wiki/IFNA8" title="IFNA8">IFNA8</a></li> <li><a href="/wiki/IFNA10" title="IFNA10">IFNA10</a></li> <li><a href="/wiki/IFNA13" title="IFNA13">IFNA13</a></li> <li><a href="/wiki/IFNA14" title="IFNA14">IFNA14</a></li> <li><a href="/wiki/IFNA16" title="IFNA16">IFNA16</a></li> <li><a href="/wiki/IFNA17" title="IFNA17">IFNA17</a></li> <li><a href="/wiki/IFNA21" title="IFNA21">IFNA21</a></li> <li><a href="/wiki/IFNB1" title="IFNB1">IFNB1</a></li> <li><a href="/wiki/IFNK" title="IFNK">IFNK</a></li> <li><a href="/wiki/IFNW1" title="IFNW1">IFNW1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interferon_type_II" class="mw-redirect" title="Interferon type II">II</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interferon_gamma" title="Interferon gamma">IFNG</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Immunoglobulin_superfamily" title="Immunoglobulin superfamily">Ig superfamily</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_1_family" class="mw-redirect" title="Interleukin 1 family">IL1 family</a>: <a href="/wiki/IL1A" class="mw-redirect" title="IL1A">IL1A/IL1F1</a></li> <li><a href="/wiki/Interleukin_1_beta" title="Interleukin 1 beta">IL1B/IL1F2</a></li> <li><a href="/wiki/Interleukin_1_receptor_antagonist" class="mw-redirect" title="Interleukin 1 receptor antagonist">1Ra/IL1F3</a></li> <li><a href="/wiki/IL1F5" class="mw-redirect" title="IL1F5">IL1F5</a></li> <li><a href="/wiki/IL36A" title="IL36A">IL1F6</a></li> <li><a href="/wiki/IL1F7" class="mw-redirect" title="IL1F7">IL1F7</a></li> <li><a href="/wiki/IL36B" title="IL36B">IL1F8</a></li> <li><a href="/wiki/IL1F9" class="mw-redirect" title="IL1F9">IL1F9</a></li> <li><a href="/wiki/IL1F10" title="IL1F10">IL1F10</a></li> <li><a href="/wiki/Interleukin_33" title="Interleukin 33">33/IL1F11</a></li> <li><a href="/wiki/Interleukin_18" title="Interleukin 18">18/IL1G</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/IL17_family" class="mw-redirect" title="IL17 family">IL17 family</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_17" title="Interleukin 17">IL17</a>/<a href="/wiki/Interleukin_25" title="Interleukin 25">IL25</a> (<a href="/wiki/IL17A" class="mw-redirect" title="IL17A">IL17A</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Hematopoietic" class="mw-redirect" title="Hematopoietic">Hematopoietic</a> <ul><li><a href="/wiki/Stem_cell_factor" title="Stem cell factor">KITLG</a></li> <li><a href="/wiki/Colony-stimulating_factor" title="Colony-stimulating factor">Colony-stimulating factor</a></li></ul></li> <li><a href="/wiki/Osteopontin" title="Osteopontin">SPP1</a></li> <li><a href="/wiki/Macrophage_migration_inhibitory_factor" title="Macrophage migration inhibitory factor">MIF</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">By function/<br />cell</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Proinflammatory_cytokine" class="mw-redirect" title="Proinflammatory cytokine">proinflammatory cytokine</a></i> <ul><li><a href="/wiki/Interleukin_1" class="mw-redirect" title="Interleukin 1">IL1</a></li> <li><a href="/wiki/Tumor_necrosis_factor_alpha" class="mw-redirect" title="Tumor necrosis factor alpha">TNFA</a></li></ul></li></ul> <ul><li><a href="/wiki/Monokine" title="Monokine">Monokine</a></li> <li><a href="/wiki/Lymphokine" title="Lymphokine">Lymphokine</a> <ul><li><i>T<sub>h</sub>1</i> <ul><li><a href="/wiki/Interferon_gamma" title="Interferon gamma">IFNγ</a></li> <li><a href="/wiki/Tumor_necrosis_factor_beta" class="mw-redirect" title="Tumor necrosis factor beta">TNFβ</a></li></ul></li> <li><i>T<sub>h</sub>2</i> <ul><li><a href="/wiki/Interleukin_4" title="Interleukin 4">IL4</a></li> <li><a href="/wiki/Interleukin_5" title="Interleukin 5">IL5</a></li> <li><a href="/wiki/Interleukin_6" title="Interleukin 6">IL6</a></li> <li><a href="/wiki/Interleukin_10" title="Interleukin 10">IL10</a></li> <li><a href="/wiki/Interleukin_13" title="Interleukin 13">IL13</a></li></ul></li></ul></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Immunostimulants_(L03)" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Immunostimulants" title="Template:Immunostimulants"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Immunostimulants" title="Template talk:Immunostimulants"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Immunostimulants" title="Special:EditPage/Template:Immunostimulants"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Immunostimulants_(L03)" style="font-size:114%;margin:0 4em"><a href="/wiki/Immunostimulant" title="Immunostimulant">Immunostimulants</a> (<a href="/wiki/ATC_code_L03" title="ATC code L03">L03</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Endogenous</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cytokine" title="Cytokine">Cytokines</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Colony-stimulating_factor" title="Colony-stimulating factor">Colony-stimulating factors</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Granulocyte_colony-stimulating_factor" title="Granulocyte colony-stimulating factor">G-CSF</a> <ul><li><a href="/wiki/Efbemalenograstim_alfa" title="Efbemalenograstim alfa">Efbemalenograstim alfa</a></li> <li><a href="/wiki/Eflapegrastim" title="Eflapegrastim">Eflapegrastim</a></li> <li><a href="/wiki/Filgrastim" title="Filgrastim">Filgrastim</a> / <a href="/wiki/Lipegfilgrastim" title="Lipegfilgrastim">Lipegfilgrastim</a> / <a href="/wiki/Pegfilgrastim" title="Pegfilgrastim">Pegfilgrastim</a></li> <li><a href="/wiki/Lenograstim" title="Lenograstim">Lenograstim</a></li></ul></li> <li><a href="/wiki/Granulocyte_macrophage_colony-stimulating_factor" class="mw-redirect" title="Granulocyte macrophage colony-stimulating factor">GM-CSF</a> <ul><li><a href="/wiki/Molgramostim" title="Molgramostim">Molgramostim</a></li> <li><a href="/wiki/Sargramostim" title="Sargramostim">Sargramostim</a></li></ul></li> <li><a href="/wiki/Stem_cell_factor" title="Stem cell factor">SCF</a> <ul><li><a href="/wiki/Ancestim" title="Ancestim">Ancestim</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interferon" title="Interferon">Interferons</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>alpha</i>: <ul><li><a href="/wiki/Albinterferon" title="Albinterferon">Albinterferon</a></li> <li><a href="/wiki/Interferon_alfa" title="Interferon alfa">Interferon alfa</a> natural</li> <li><a href="/wiki/Interferon_alfa_2a" class="mw-redirect" title="Interferon alfa 2a">Interferon alfa 2a</a> / <a class="mw-selflink selflink">Peginterferon alfa-2a</a></li> <li><a href="/wiki/Interferon_alfa_2b" class="mw-redirect" title="Interferon alfa 2b">Interferon alfa 2b</a> / <a href="/wiki/Peginterferon_alfa-2b" title="Peginterferon alfa-2b">Peginterferon alfa-2b</a> / <a href="/wiki/Ropeginterferon_alfa-2b" title="Ropeginterferon alfa-2b">Ropeginterferon alfa-2b</a></li> <li><a href="/w/index.php?title=Interferon_alfa_n1&action=edit&redlink=1" class="new" title="Interferon alfa n1 (page does not exist)">Interferon alfa n1</a></li> <li><a href="/wiki/Interferon_alfacon-1" title="Interferon alfacon-1">Interferon alfacon-1</a></li> <li><a href="/wiki/Interferon_alpha-n3" title="Interferon alpha-n3">Interferon alpha-n3</a></li> <li><a href="/wiki/Recombinant_feline_interferon_omega" title="Recombinant feline interferon omega">feline "omega"</a></li></ul></li> <li><i>beta</i>: <ul><li><a href="/wiki/Interferon_beta" class="mw-redirect" title="Interferon beta">Interferon beta</a> natural</li> <li><a href="/wiki/Interferon_beta_1a" class="mw-redirect" title="Interferon beta 1a">Interferon beta 1a</a></li> <li><a href="/wiki/Interferon_beta_1b" class="mw-redirect" title="Interferon beta 1b">Interferon beta 1b</a></li></ul></li> <li><a href="/wiki/Interferon_gamma" title="Interferon gamma">Interferon gamma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interleukin" title="Interleukin">Interleukins</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interleukin_2" title="Interleukin 2">Aldesleukin</a></li> <li><a href="/wiki/Oprelvekin" title="Oprelvekin">Oprelvekin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other protein / peptide</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Growth_hormone" title="Growth hormone">Growth hormone</a></li> <li><a href="/wiki/Immunocyanin" class="mw-redirect" title="Immunocyanin">Immunocyanin</a></li> <li><a href="/wiki/Pegademase" class="mw-redirect" title="Pegademase">Pegademase</a></li> <li><a href="/wiki/Prolactin" title="Prolactin">Prolactin</a></li> <li><a href="/wiki/Tasonermin" class="mw-redirect" title="Tasonermin">Tasonermin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Female_sex_steroids" class="mw-redirect" title="Female sex steroids">Female sex steroids</a></li> <li><a href="/wiki/Histamine_dihydrochloride" title="Histamine dihydrochloride">Histamine dihydrochloride</a></li> <li><a href="/wiki/Poly_ICLC" title="Poly ICLC">Poly ICLC</a></li> <li><a href="/wiki/Vitamin_D" title="Vitamin D">Vitamin D</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Exogenous</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Beta-glucan" title="Beta-glucan">beta-glucan</a> <ul><li><a href="/wiki/Lentinan" title="Lentinan">Lentinan</a></li></ul></li> <li><a href="/wiki/Heterocyclic_compound" title="Heterocyclic compound">heterocyclic compound</a> <ul><li><a href="/wiki/Plerixafor" title="Plerixafor">Plerixafor</a></li></ul></li> <li><a href="/wiki/8-Hydroxyquinoline" title="8-Hydroxyquinoline">hydroxyquinoline</a> <ul><li><a href="/wiki/Roquinimex" class="mw-redirect" title="Roquinimex">Roquinimex</a></li></ul></li> <li><a href="/wiki/Mifamurtide" title="Mifamurtide">Mifamurtide</a></li> <li><a href="/wiki/Oligopeptide" title="Oligopeptide">oligopeptides</a> <ul><li><a href="/wiki/Glatiramer_acetate" title="Glatiramer acetate">Glatiramer acetate</a></li> <li><a href="/wiki/Thymopentin" title="Thymopentin">Thymopentin</a></li> <li><a href="/wiki/Thymosin_%CE%B11" title="Thymosin α1">Thymosin α1</a></li> <li><a href="/wiki/Thymulin" title="Thymulin">Thymulin</a></li></ul></li> <li><a href="/wiki/Polyribonucleotide" class="mw-redirect" title="Polyribonucleotide">polyribonucleotide</a> <ul><li><a href="/wiki/Polyinosinic:polycytidylic_acid" title="Polyinosinic:polycytidylic acid">Polyinosinic:polycytidylic acid</a></li></ul></li> <li><a href="/wiki/Thiazolidine" title="Thiazolidine">thiazolidine</a> <ul><li><a href="/wiki/Pidotimod" title="Pidotimod">Pidotimod</a></li></ul></li> <li><a href="/wiki/Inosine_pranobex" title="Inosine pranobex">Inosine pranobex</a></li> <li><a href="/wiki/Vaccine" title="Vaccine">vaccines</a> <ul><li><a href="/wiki/Bacillus_Calmette%E2%80%93Gu%C3%A9rin" class="mw-redirect" title="Bacillus Calmette–Guérin">Bacillus Calmette–Guérin</a></li> <li><a href="/wiki/Melanoma_vaccine" class="mw-redirect" title="Melanoma vaccine">Melanoma vaccine</a></li> <li><a href="/wiki/Sipuleucel-T" title="Sipuleucel-T">Sipuleucel-T</a></li></ul></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-labelledby="DNA_virus_antivirals_(primarily_J05,_also_S01AD_and_D06BB)" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:DNA_antivirals" title="Template:DNA antivirals"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:DNA_antivirals" title="Template talk:DNA antivirals"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:DNA_antivirals" title="Special:EditPage/Template:DNA antivirals"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="DNA_virus_antivirals_(primarily_J05,_also_S01AD_and_D06BB)" style="font-size:114%;margin:0 4em"><a href="/wiki/DNA_virus" title="DNA virus">DNA virus</a> <a href="/wiki/Antiviral_drug" title="Antiviral drug">antivirals</a> (primarily <a href="/wiki/ATC_code_J05" title="ATC code J05">J05</a>, also <a href="/wiki/ATC_code_S01#S01AD" title="ATC code S01">S01AD</a> and <a href="/wiki/ATC_code_D06#D06BB" title="ATC code D06">D06BB</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Baltimore_classification" title="Baltimore classification">Baltimore I</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Herpesviridae" title="Herpesviridae">Herpesvirus</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">DNA-synthesis<br />inhibitor</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Thymidine_kinase_from_herpesvirus" title="Thymidine kinase from herpesvirus">TK</a> activated</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Purine_analogue" title="Purine analogue">Purine analogue</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Guanine" title="Guanine">guanine</a></i> (<a href="/wiki/Aciclovir" title="Aciclovir">Aciclovir</a><sup>#</sup>/<a href="/wiki/Valaciclovir" title="Valaciclovir">Valaciclovir</a></li> <li><a href="/wiki/Ganciclovir" title="Ganciclovir">Ganciclovir</a>/<a href="/wiki/Valganciclovir" title="Valganciclovir">Valganciclovir</a><sup>#</sup></li> <li><a href="/wiki/Penciclovir" title="Penciclovir">Penciclovir</a>/<a href="/wiki/Famciclovir" title="Famciclovir">Famciclovir</a>)</li></ul> <ul><li><i><a href="/wiki/Adenine" title="Adenine">adenine</a></i> (<a href="/wiki/Vidarabine" title="Vidarabine">Vidarabine</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pyrimidine_analogue" title="Pyrimidine analogue">Pyrimidine analogue</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Uridine" title="Uridine">uridine</a></i> (<a href="/wiki/Idoxuridine" title="Idoxuridine">Idoxuridine</a></li> <li><a href="/wiki/Trifluridine" title="Trifluridine">Trifluridine</a> (<a href="/wiki/Trifluridine/tipiracil" title="Trifluridine/tipiracil">+tipiracil</a>)</li> <li><a href="/wiki/Edoxudine" title="Edoxudine">Edoxudine</a>)</li></ul> <ul><li><i><a href="/wiki/Thymine" title="Thymine">thymine</a></i> <ul><li><a href="/wiki/Brivudine" title="Brivudine">Brivudine</a></li> <li><a href="/wiki/FV-100" title="FV-100">FV-100</a><sup>†</sup></li> <li><a href="/wiki/Sorivudine" title="Sorivudine">Sorivudine</a><sup>‡</sup></li></ul></li></ul> <ul><li><i><a href="/wiki/Cytosine" title="Cytosine">cytosine</a></i> (<a href="/wiki/Cytarabine" title="Cytarabine">Cytarabine</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Not TK activated</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Foscarnet" title="Foscarnet">Foscarnet</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Amenamevir" title="Amenamevir">Amenamevir</a></li> <li><a href="/wiki/Docosanol" class="mw-redirect" title="Docosanol">Docosanol</a></li> <li><a href="/wiki/Letermovir" title="Letermovir">Letermovir</a></li> <li><a href="/wiki/Maribavir" title="Maribavir">Maribavir</a></li> <li><i><a href="/wiki/Early_protein" title="Early protein">early protein</a></i> (<a href="/wiki/Fomivirsen" title="Fomivirsen">Fomivirsen</a><sup>‡</sup>)</li> <li><a href="/wiki/Tromantadine" title="Tromantadine">Tromantadine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Human_papillomavirus" class="mw-redirect" title="Human papillomavirus">HPV</a>/<a href="/wiki/Molluscum_contagiosum" title="Molluscum contagiosum">MC</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Imiquimod" title="Imiquimod">Imiquimod</a>/<a href="/wiki/Resiquimod" title="Resiquimod">Resiquimod</a></li> <li><a href="/wiki/Podophyllotoxin" title="Podophyllotoxin">Podophyllotoxin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Vaccinia" title="Vaccinia">Vaccinia</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Antiviral_drug#Assembly" title="Antiviral drug">assembly</a>:</i> <a href="/wiki/Rifampicin" title="Rifampicin">Rifampicin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Poxviridae" title="Poxviridae">Poxviridae</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Methisazone" class="mw-redirect" title="Methisazone">Methisazone</a></li> <li><a href="/wiki/Tecovirimat" title="Tecovirimat">Tecovirimat</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Hepatitis_B" title="Hepatitis B">Hepatitis B</a> (VII)</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Nucleoside_analogue" title="Nucleoside analogue">Nucleoside analogues</a>/<a href="/wiki/Reverse-transcriptase_inhibitor#Nucleoside_analog_reverse_transcriptase_inhibitors_.28NARTIs_or_NRTIs.29" title="Reverse-transcriptase inhibitor">NARTIs</a>:</i> <a href="/wiki/Entecavir" title="Entecavir">Entecavir</a><sup>#</sup></li> <li><a href="/wiki/Lamivudine" title="Lamivudine">Lamivudine</a></li> <li><a href="/wiki/Lobucavir" title="Lobucavir">Lobucavir</a><sup>†</sup></li> <li><a href="/wiki/Telbivudine" title="Telbivudine">Telbivudine</a></li> <li><a href="/wiki/Clevudine" title="Clevudine">Clevudine</a></li></ul> <ul><li><i><a href="/wiki/Nucleotide_analogue" class="mw-redirect" title="Nucleotide analogue">Nucleotide analogues</a>/<a href="/wiki/Reverse-transcriptase_inhibitor#Nucleotide_analog_reverse_transcriptase_inhibitors_.28NtARTIs_or_NtRTIs.29" title="Reverse-transcriptase inhibitor">NtRTIs</a>:</i> <a href="/wiki/Adefovir" title="Adefovir">Adefovir</a></li> <li><a href="/wiki/Tenofovir_disoproxil" title="Tenofovir disoproxil">Tenofovir disoproxil</a></li> <li><a href="/wiki/Tenofovir_alafenamide" title="Tenofovir alafenamide">Tenofovir alafenamide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Multiple/general</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Nucleic acid inhibitors</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cidofovir" title="Cidofovir">Cidofovir</a></li> <li><a href="/wiki/Brincidofovir" title="Brincidofovir">Brincidofovir</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interferon" title="Interferon">Interferon</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interferon_alfa_2b" class="mw-redirect" title="Interferon alfa 2b">Interferon alfa 2b</a></li> <li><a class="mw-selflink selflink">Peginterferon alfa-2a</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Multiple/unknown</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Filociclovir" title="Filociclovir">Filociclovir</a><sup>†</sup></li> <li><a href="/wiki/Ribavirin" title="Ribavirin">Ribavirin</a><sup>#</sup>/<a href="/wiki/Taribavirin" title="Taribavirin">Taribavirin</a><sup><b>†</b></sup></li> <li><a href="/wiki/Moroxydine" title="Moroxydine">Moroxydine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-labelledby="RNA_virus_antivirals_(primarily_J05,_also_S01AD_and_D06BB)" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:RNA_antivirals" title="Template:RNA antivirals"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:RNA_antivirals" title="Template talk:RNA antivirals"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:RNA_antivirals" title="Special:EditPage/Template:RNA antivirals"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="RNA_virus_antivirals_(primarily_J05,_also_S01AD_and_D06BB)" style="font-size:114%;margin:0 4em"><a href="/wiki/RNA_virus" title="RNA virus">RNA virus</a> <a href="/wiki/Antiviral_drug" title="Antiviral drug">antivirals</a> (primarily <a href="/wiki/ATC_code_J05" title="ATC code J05">J05</a>, also <a href="/wiki/ATC_code_S01#S01AD" title="ATC code S01">S01AD</a> and <a href="/wiki/ATC_code_D06#D06BB" title="ATC code D06">D06BB</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Hepatitis_C" title="Hepatitis C">Hepatitis C</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/NS3_(HCV)" class="mw-redirect" title="NS3 (HCV)">NS3</a>/<a href="/wiki/NS4A" class="mw-redirect" title="NS4A">4A</a> protease inhibitors (–previr)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Asunaprevir" title="Asunaprevir">Asunaprevir</a></li> <li><a href="/wiki/Boceprevir" title="Boceprevir">Boceprevir</a><sup><b>‡</b></sup></li> <li><a href="/wiki/Ciluprevir" title="Ciluprevir">Ciluprevir</a><sup><b>§</b></sup></li> <li><a href="/wiki/Danoprevir" title="Danoprevir">Danoprevir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Faldaprevir" title="Faldaprevir">Faldaprevir</a><sup><b>‡</b></sup></li> <li><a href="/wiki/Glecaprevir" title="Glecaprevir">Glecaprevir</a></li> <li><a href="/wiki/Grazoprevir" title="Grazoprevir">Grazoprevir</a></li> <li><a href="/wiki/Narlaprevir" title="Narlaprevir">Narlaprevir</a></li> <li><a href="/wiki/Paritaprevir" title="Paritaprevir">Paritaprevir</a></li> <li><a href="/wiki/Simeprevir" title="Simeprevir">Simeprevir</a></li> <li><a href="/wiki/Sovaprevir" title="Sovaprevir">Sovaprevir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Telaprevir" title="Telaprevir">Telaprevir</a><sup><b>‡</b></sup></li> <li><a href="/wiki/Vaniprevir" title="Vaniprevir">Vaniprevir</a></li> <li><a href="/w/index.php?title=Vedroprevir&action=edit&redlink=1" class="new" title="Vedroprevir (page does not exist)">Vedroprevir</a><sup><b>§</b></sup></li> <li><a href="/wiki/Voxilaprevir" title="Voxilaprevir">Voxilaprevir</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/NS5A" class="mw-redirect" title="NS5A">NS5A</a> inhibitors (–asvir)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Coblopasvir" title="Coblopasvir">Coblopasvir</a></li> <li><a href="/wiki/Daclatasvir" title="Daclatasvir">Daclatasvir</a><sup><b>#</b></sup></li> <li><a href="/wiki/Elbasvir" title="Elbasvir">Elbasvir</a></li> <li><a href="/wiki/Ledipasvir" title="Ledipasvir">Ledipasvir</a></li> <li><a href="/wiki/Odalasvir" title="Odalasvir">Odalasvir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Ombitasvir" title="Ombitasvir">Ombitasvir</a></li> <li><a href="/wiki/Pibrentasvir" title="Pibrentasvir">Pibrentasvir</a></li> <li><a href="/wiki/Ravidasvir" title="Ravidasvir">Ravidasvir</a><sup><b>†</b></sup></li> <li><a href="/w/index.php?title=Ruzasvir&action=edit&redlink=1" class="new" title="Ruzasvir (page does not exist)">Ruzasvir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Samatasvir" title="Samatasvir">Samatasvir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Velpatasvir" title="Velpatasvir">Velpatasvir</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/NS5B" class="mw-redirect" title="NS5B">NS5B</a> <a href="/wiki/RNA_polymerase" title="RNA polymerase">RNA polymerase</a> inhibitors (–buvir)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Beclabuvir" title="Beclabuvir">Beclabuvir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Bemnifosbuvir" title="Bemnifosbuvir">Bemnifosbuvir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Dasabuvir" title="Dasabuvir">Dasabuvir</a><sup><b>#</b></sup></li> <li><a href="/wiki/Deleobuvir" title="Deleobuvir">Deleobuvir</a><sup><b>§</b></sup></li> <li><a href="/wiki/Filibuvir" title="Filibuvir">Filibuvir</a><sup><b>§</b></sup></li> <li><a href="/wiki/GS-6620" title="GS-6620">GS-6620</a><sup><b>§</b></sup></li> <li><a href="/wiki/IDX-184" title="IDX-184">IDX-184</a><sup><b>§</b></sup></li> <li><a href="/wiki/Setrobuvir" title="Setrobuvir">Setrobuvir</a><sup><b>§</b></sup></li> <li><a href="/wiki/Sofosbuvir" title="Sofosbuvir">Sofosbuvir</a><sup><b>#</b></sup></li> <li><a href="/w/index.php?title=Tegobuvir&action=edit&redlink=1" class="new" title="Tegobuvir (page does not exist)">Tegobuvir</a><sup><b>§</b></sup></li> <li><a href="/wiki/TMC-647055" title="TMC-647055">TMC-647055</a><sup><b>§</b></sup></li> <li><a href="/wiki/Radalbuvir" title="Radalbuvir">Radalbuvir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Uprifosbuvir" title="Uprifosbuvir">Uprifosbuvir</a><sup><b>†</b></sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Combination drugs</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Elbasvir/grazoprevir" title="Elbasvir/grazoprevir">Elbasvir/grazoprevir</a></li> <li><a href="/wiki/Glecaprevir/pibrentasvir" title="Glecaprevir/pibrentasvir">Glecaprevir/pibrentasvir</a></li> <li><a href="/wiki/Ledipasvir/sofosbuvir" title="Ledipasvir/sofosbuvir">Ledipasvir/sofosbuvir</a><sup><b>#</b></sup></li> <li><a href="/wiki/Ombitasvir/paritaprevir/ritonavir" title="Ombitasvir/paritaprevir/ritonavir">Ombitasvir/paritaprevir/ritonavir</a><sup><b>#</b></sup></li> <li><a href="/wiki/Sofosbuvir/daclatasvir" title="Sofosbuvir/daclatasvir">Sofosbuvir/daclatasvir</a></li> <li><a href="/wiki/Sofosbuvir/velpatasvir" title="Sofosbuvir/velpatasvir">Sofosbuvir/velpatasvir</a><sup><b>#</b></sup></li> <li><a href="/wiki/Sofosbuvir/velpatasvir/voxilaprevir" title="Sofosbuvir/velpatasvir/voxilaprevir">Sofosbuvir/velpatasvir/voxilaprevir</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Hepatitis_D" title="Hepatitis D">Hepatitis D</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bulevirtide" title="Bulevirtide">Bulevirtide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Picornavirus" title="Picornavirus">Picornavirus</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Viral_entry" title="Viral entry">viral entry</a>:</i> <a href="/wiki/Pleconaril" title="Pleconaril">Pleconaril</a><sup><b>†</b></sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Anti-<a href="/wiki/Influenza" title="Influenza">influenza</a> agents</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Baloxavir_marboxil" title="Baloxavir marboxil">Baloxavir marboxil</a></li> <li><a href="/wiki/Pimodivir" title="Pimodivir">Pimodivir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Umifenovir" title="Umifenovir">Umifenovir</a></li></ul> <ul><li><i><a href="/wiki/Adamantane" title="Adamantane">adamantane derivatives</a>/<a href="/wiki/M2_protein" class="mw-redirect" title="M2 protein">M2 inhibitors</a></i> (<a href="/wiki/Adapromine" title="Adapromine">Adapromine</a></li> <li><a href="/wiki/Amantadine" title="Amantadine">Amantadine</a></li> <li><a href="/wiki/Rimantadine" title="Rimantadine">Rimantadine</a>)</li></ul> <ul><li><i><a href="/wiki/Neuraminidase_inhibitor" title="Neuraminidase inhibitor">neuraminidase inhibitors</a>/<a href="/wiki/Antiviral_drug#Release_phase" title="Antiviral drug">release phase</a></i> (<a href="/wiki/Oseltamivir" title="Oseltamivir">Oseltamivir</a><sup><b>#</b></sup></li> <li><a href="/wiki/Zanamivir" title="Zanamivir">Zanamivir</a></li> <li><a href="/wiki/Peramivir" title="Peramivir">Peramivir</a>, <a href="/wiki/Laninamivir" title="Laninamivir">Laninamivir</a><sup><b>†</b></sup>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Multiple/general</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Interferon" title="Interferon">Interferon</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interferon_alfa_2b" class="mw-redirect" title="Interferon alfa 2b">Interferon alfa 2b</a></li> <li><a class="mw-selflink selflink">Peginterferon alfa-2a</a><sup><b>#</b></sup></li> <li><a href="/wiki/Peginterferon_alfa-2b" title="Peginterferon alfa-2b">Peginterferon alfa-2b</a><sup><b>#</b></sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/3C-like_protease" title="3C-like protease">3CL protease</a> inhibitors (–trelvir)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ensitrelvir" title="Ensitrelvir">Ensitrelvir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Ibuzatrelvir" title="Ibuzatrelvir">Ibuzatrelvir</a></li> <li><a href="/wiki/Lufotrelvir" title="Lufotrelvir">Lufotrelvir</a></li> <li><a href="/wiki/Nirmatrelvir" title="Nirmatrelvir">Nirmatrelvir</a><sup><b>†</b></sup> (<a href="/wiki/Nirmatrelvir/ritonavir" title="Nirmatrelvir/ritonavir">+ritonavir</a>)<sup><b>†</b></sup></li> <li><a href="/wiki/Rupintrivir" title="Rupintrivir">Rupintrivir</a></li> <li><a href="/wiki/Simnotrelvir" class="mw-redirect" title="Simnotrelvir">Simnotrelvir</a> (<a href="/wiki/Simnotrelvir/ritonavir" title="Simnotrelvir/ritonavir">+ritonavir</a><sup><b>†</b></sup>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">RNA pol inhibitors</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CMX521" title="CMX521">CMX521</a><sup><b>§</b></sup></li> <li><a href="/wiki/Deuremidevir" title="Deuremidevir">Deuremidevir</a><sup><b>†</b></sup></li> <li><a href="/wiki/Favipiravir" title="Favipiravir">Favipiravir</a></li> <li><a href="/wiki/Galidesivir" title="Galidesivir">Galidesivir</a><sup><b>†</b></sup></li> <li><a href="/wiki/GS-441524" title="GS-441524">GS-441524</a><sup><b>§</b></sup></li> <li><a href="/wiki/Remdesivir" title="Remdesivir">Remdesivir</a></li> <li><a href="/wiki/MK-608" title="MK-608">MK-608</a><sup><b>§</b></sup></li> <li><a href="/wiki/Mericitabine" title="Mericitabine">Mericitabine</a><sup><b>†</b></sup></li> <li><a href="/wiki/Molnupiravir" title="Molnupiravir">Molnupiravir</a></li> <li><a href="/wiki/NITD008" title="NITD008">NITD008</a><sup><b>§</b></sup></li> <li><a href="/wiki/Ribavirin" title="Ribavirin">Ribavirin</a><sup><b>#</b></sup></li> <li><a href="/wiki/Taribavirin" title="Taribavirin">Taribavirin</a><sup><b>†</b></sup></li> <li><a href="/wiki/Triazavirin" class="mw-redirect" title="Triazavirin">Triazavirin</a></li> <li><a href="/wiki/Valopicitabine" title="Valopicitabine">Valopicitabine</a><sup><b>†</b></sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Multiple/Unknown/Other</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/EICAR_(antiviral)" title="EICAR (antiviral)">EICAR</a><sup><b>§</b></sup></li> <li><a href="/wiki/Merimepodib" title="Merimepodib">Merimepodib</a><sup><b>§</b></sup></li> <li><a href="/wiki/Moroxydine" title="Moroxydine">Moroxydine</a></li> <li><a href="/wiki/Presatovir" title="Presatovir">Presatovir</a><sup><b>†</b></sup></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Cytokine_receptor_modulators" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Cytokine_receptor_modulators" title="Template:Cytokine receptor modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Cytokine_receptor_modulators" title="Template talk:Cytokine receptor modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Cytokine_receptor_modulators" title="Special:EditPage/Template:Cytokine receptor modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Cytokine_receptor_modulators" style="font-size:114%;margin:0 4em"><a href="/wiki/Cytokine_receptor" title="Cytokine receptor">Cytokine receptor</a> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Chemokine_receptor" title="Chemokine receptor">Chemokine</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>See <a href="/wiki/Template:Chemokine_receptor_modulators" title="Template:Chemokine receptor modulators">here</a> instead.</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Colony-stimulating_factor_receptor" class="mw-redirect" title="Colony-stimulating factor receptor">CSF</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Erythropoietin_receptor" title="Erythropoietin receptor">Erythropoietin</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/w/index.php?title=ARA-290&action=edit&redlink=1" class="new" title="ARA-290 (page does not exist)">ARA-290</a></li> <li><a href="/w/index.php?title=Asialo_erythropoietin&action=edit&redlink=1" class="new" title="Asialo erythropoietin (page does not exist)">Asialo erythropoietin</a></li> <li><a href="/w/index.php?title=Carbamylated_erythropoietin&action=edit&redlink=1" class="new" title="Carbamylated erythropoietin (page does not exist)">Carbamylated erythropoietin</a></li> <li><a href="/w/index.php?title=CNTO-530&action=edit&redlink=1" class="new" title="CNTO-530 (page does not exist)">CNTO-530</a></li> <li><a href="/wiki/Darbepoetin_alfa" title="Darbepoetin alfa">Darbepoetin alfa</a></li> <li><a href="/wiki/Epoetin_alfa" title="Epoetin alfa">Epoetin alfa</a></li> <li><a href="/wiki/Epoetin_beta" title="Epoetin beta">Epoetin beta</a></li> <li><a href="/w/index.php?title=Epoetin_delta&action=edit&redlink=1" class="new" title="Epoetin delta (page does not exist)">Epoetin delta</a></li> <li><a href="/w/index.php?title=Epoetin_epsilon&action=edit&redlink=1" class="new" title="Epoetin epsilon (page does not exist)">Epoetin epsilon</a></li> <li><a href="/w/index.php?title=Epoetin_gamma&action=edit&redlink=1" class="new" title="Epoetin gamma (page does not exist)">Epoetin gamma</a></li> <li><a href="/w/index.php?title=Epoetin_kappa&action=edit&redlink=1" class="new" title="Epoetin kappa (page does not exist)">Epoetin kappa</a></li> <li><a href="/w/index.php?title=Epoetin_omega&action=edit&redlink=1" class="new" title="Epoetin omega (page does not exist)">Epoetin omega</a></li> <li><a href="/wiki/Epoetin_theta" title="Epoetin theta">Epoetin theta</a></li> <li><a href="/wiki/Epoetin_zeta" class="mw-redirect" title="Epoetin zeta">Epoetin zeta</a></li> <li><a href="/wiki/Erythropoietin" title="Erythropoietin">Erythropoietin (EPO)</a></li> <li><a href="/w/index.php?title=Erythropoietin-Fc&action=edit&redlink=1" class="new" title="Erythropoietin-Fc (page does not exist)">Erythropoietin-Fc</a></li> <li><a href="/wiki/Methoxy_polyethylene_glycol-epoetin_beta" title="Methoxy polyethylene glycol-epoetin beta">Methoxy polyethylene glycol-epoetin beta (CERA/Mircera)</a></li> <li><a href="/wiki/Peginesatide" title="Peginesatide">Peginesatide</a></li> <li><a href="/w/index.php?title=Pegol_sihematide&action=edit&redlink=1" class="new" title="Pegol sihematide (page does not exist)">Pegol sihematide (EPO-018B)</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Granulocyte_colony-stimulating_factor_receptor" title="Granulocyte colony-stimulating factor receptor">G-CSF (CSF3)</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/Filgrastim" title="Filgrastim">Filgrastim</a></li> <li><a href="/wiki/Granulocyte_colony-stimulating_factor" title="Granulocyte colony-stimulating factor">Granulocyte colony-stimulating factor</a></li> <li><a href="/wiki/Lenograstim" title="Lenograstim">Lenograstim</a></li> <li><a href="/w/index.php?title=Leridistim&action=edit&redlink=1" class="new" title="Leridistim (page does not exist)">Leridistim</a></li> <li><a href="/wiki/Lipegfilgrastim" title="Lipegfilgrastim">Lipegfilgrastim</a></li> <li><a href="/w/index.php?title=Nartograstim&action=edit&redlink=1" class="new" title="Nartograstim (page does not exist)">Nartograstim</a></li> <li><a href="/wiki/Pegfilgrastim" title="Pegfilgrastim">Pegfilgrastim</a></li> <li><a href="/w/index.php?title=Pegnartograstim&action=edit&redlink=1" class="new" title="Pegnartograstim (page does not exist)">Pegnartograstim</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Granulocyte_macrophage_colony-stimulating_factor_receptor" class="mw-redirect" title="Granulocyte macrophage colony-stimulating factor receptor">GM-CSF (CSF2)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/w/index.php?title=Ecogramostim&action=edit&redlink=1" class="new" title="Ecogramostim (page does not exist)">Ecogramostim</a></li> <li><a href="/wiki/Granulocyte_macrophage_colony-stimulating_factor" class="mw-redirect" title="Granulocyte macrophage colony-stimulating factor">Granulocyte macrophage colony-stimulating factor</a></li> <li><a href="/w/index.php?title=Milodistim&action=edit&redlink=1" class="new" title="Milodistim (page does not exist)">Milodistim</a></li> <li><a href="/wiki/Molgramostim" title="Molgramostim">Molgramostim</a></li> <li><a href="/w/index.php?title=Regramostim&action=edit&redlink=1" class="new" title="Regramostim (page does not exist)">Regramostim</a></li> <li><a href="/wiki/Sargramostim" title="Sargramostim">Sargramostim</a></li></ul> <ul><li><i>Antibodies:</i> <a href="/wiki/Mavrilimumab" title="Mavrilimumab">Mavrilimumab</a></li> <li><a href="/wiki/Namilumab" title="Namilumab">Namilumab</a></li> <li><a href="/wiki/Otilimab" title="Otilimab">Otilimab</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Macrophage_colony-stimulating_factor_receptor" class="mw-redirect" title="Macrophage colony-stimulating factor receptor">M-CSF (CSF1)</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/w/index.php?title=Cilmostim&action=edit&redlink=1" class="new" title="Cilmostim (page does not exist)">Cilmostim</a></li> <li><a href="/wiki/Interleukin-34" class="mw-redirect" title="Interleukin-34">Interleukin-34</a></li> <li><a href="/w/index.php?title=Lanimostim&action=edit&redlink=1" class="new" title="Lanimostim (page does not exist)">Lanimostim</a></li> <li><a href="/wiki/Macrophage_colony-stimulating_factor" title="Macrophage colony-stimulating factor">Macrophage colony-stimulating factor</a></li> <li><a href="/w/index.php?title=Mirimostim&action=edit&redlink=1" class="new" title="Mirimostim (page does not exist)">Mirimostim</a></li></ul> <ul><li><i>Kinase inhibitors:</i> <a href="/w/index.php?title=Agerafenib&action=edit&redlink=1" class="new" title="Agerafenib (page does not exist)">Agerafenib</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/CD117" class="mw-redirect" title="CD117">SCF (c-Kit)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>See <a href="/wiki/Template:Growth_factor_receptor_modulators" title="Template:Growth factor receptor modulators">here</a> instead.</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Thrombopoietin_receptor" title="Thrombopoietin receptor">Thrombopoietin</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/Eltrombopag" title="Eltrombopag">Eltrombopag</a></li> <li><a href="/w/index.php?title=Pegacaristim&action=edit&redlink=1" class="new" title="Pegacaristim (page does not exist)">Pegacaristim</a></li> <li><a href="/wiki/Promegapoietin" title="Promegapoietin">Promegapoietin</a></li> <li><a href="/wiki/Romiplostim" title="Romiplostim">Romiplostim</a></li> <li><a href="/wiki/Thrombopoietin" title="Thrombopoietin">Thrombopoietin (THPO, MGDF)</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Interferon_receptor" class="mw-redirect" title="Interferon receptor">Interferon</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Interferon-alpha/beta_receptor" title="Interferon-alpha/beta receptor">IFNAR (α/β, I)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/Albinterferon" title="Albinterferon">Albinterferon</a></li> <li><a href="/wiki/Interferon_alpha" class="mw-redirect" title="Interferon alpha">Interferon alpha (interferon alfa, IFN-α)</a></li> <li><a href="/wiki/Interferon_alfa" title="Interferon alfa">Interferon alfa</a> (<a href="/wiki/Interferon_alpha_1" class="mw-redirect" title="Interferon alpha 1">IFNA1</a>, <a href="/wiki/IFNA2" title="IFNA2">IFNA2</a>, <a href="/wiki/IFNA4" title="IFNA4">IFNA4</a>, <a href="/wiki/IFNA5" title="IFNA5">IFNA5</a>, <a href="/wiki/IFNA6" title="IFNA6">IFNA6</a>, <a href="/wiki/IFNA7" title="IFNA7">IFNA7</a>, <a href="/wiki/IFNA8" title="IFNA8">IFNA8</a>, <a href="/wiki/IFNA10" title="IFNA10">IFNA10</a>, <a href="/wiki/IFNA13" title="IFNA13">IFNA13</a>, <a href="/wiki/IFNA14" title="IFNA14">IFNA14</a>, <a href="/wiki/IFNA16" title="IFNA16">IFNA16</a>, <a href="/wiki/IFNA17" title="IFNA17">IFNA17</a>, <a href="/wiki/IFNA21" title="IFNA21">IFNA21</a>)</li> <li><a href="/wiki/Interferon_alfa_2a" class="mw-redirect" title="Interferon alfa 2a">Interferon alfa 2a</a></li> <li><a href="/wiki/Interferon_alfa_2b" class="mw-redirect" title="Interferon alfa 2b">Interferon alfa 2b</a></li> <li><a href="/w/index.php?title=Interferon_alfa_n1&action=edit&redlink=1" class="new" title="Interferon alfa n1 (page does not exist)">Interferon alfa n1</a></li> <li><a href="/wiki/Interferon_alfacon-1" title="Interferon alfacon-1">Interferon alfacon-1</a></li> <li><a href="/wiki/Interferon_alpha-n3" title="Interferon alpha-n3">Interferon alpha-n3</a></li> <li><a href="/wiki/Interferon_beta" class="mw-redirect" title="Interferon beta">Interferon beta (IFN-β)</a> (<a href="/wiki/IFNB1" title="IFNB1">IFNB1</a>, <a href="/w/index.php?title=IFNB3&action=edit&redlink=1" class="new" title="IFNB3 (page does not exist)">IFNB3</a>)</li> <li><a href="/wiki/Interferon_beta_1a" class="mw-redirect" title="Interferon beta 1a">Interferon beta 1a</a></li> <li><a href="/wiki/Interferon_beta_1b" class="mw-redirect" title="Interferon beta 1b">Interferon beta 1b</a></li> <li><a href="/wiki/Interferon_kappa" class="mw-redirect" title="Interferon kappa">Interferon kappa (IFN-ε/κ/τ/ζ, IFNK)</a></li> <li><a href="/wiki/Interferon_omega" class="mw-redirect" title="Interferon omega">Interferon omega (IFN-ω, IFNW1)</a></li> <li><a class="mw-selflink selflink">Peginterferon alfa-2a</a></li> <li><a href="/wiki/Peginterferon_alfa-2b" title="Peginterferon alfa-2b">Peginterferon alfa-2b</a></li></ul> <ul><li><i>Antibodies:</i> <a href="/wiki/Anifrolumab" title="Anifrolumab">Anifrolumab</a></li> <li><a href="/wiki/Faralimomab" title="Faralimomab">Faralimomab</a></li> <li><a href="/w/index.php?title=MEDI-545&action=edit&redlink=1" class="new" title="MEDI-545 (page does not exist)">MEDI-545</a></li> <li><a href="/wiki/Rontalizumab" title="Rontalizumab">Rontalizumab</a></li> <li><a href="/wiki/Sifalimumab" title="Sifalimumab">Sifalimumab</a></li></ul> <ul><li><i>Decoy receptors:</i> <a href="/w/index.php?title=Bifarcept&action=edit&redlink=1" class="new" title="Bifarcept (page does not exist)">Bifarcept</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Interferon-gamma_receptor" title="Interferon-gamma receptor">IFNGR (γ, II)</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/Interferon_gamma" title="Interferon gamma">Interferon gamma (IFN-γ)</a></li> <li><a href="/wiki/Interferon_gamma_1b" class="mw-redirect" title="Interferon gamma 1b">Interferon gamma 1b</a></li></ul> <ul><li><i>Antibodies:</i> <a href="/wiki/Emapalumab" title="Emapalumab">Emapalumab</a></li> <li><a href="/wiki/Fontolizumab" title="Fontolizumab">Fontolizumab</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Interferon-lambda_receptor" class="mw-redirect" title="Interferon-lambda receptor">IFNLR (λ, III)</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>See IL-28R (IFNLR) <a href="/wiki/Template:Interleukin_receptor_modulators" title="Template:Interleukin receptor modulators">here</a> instead.</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Interleukin_receptor" title="Interleukin receptor">Interleukin</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>See <a href="/wiki/Template:Interleukin_receptor_modulators" title="Template:Interleukin receptor modulators">here</a> instead.</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Transforming_growth_factor_beta_receptor" class="mw-redirect" title="Transforming growth factor beta receptor">TGFβ</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>See <a href="/wiki/Template:TGF%CE%B2_receptor_superfamily_modulators" title="Template:TGFβ receptor superfamily modulators">here</a> instead.</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Tumor_necrosis_factor_receptor" class="mw-redirect" title="Tumor necrosis factor receptor">TNF</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>See <a href="/wiki/Template:TNF_receptor_superfamily_modulators" title="Template:TNF receptor superfamily modulators">here</a> instead.</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Others</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Janus_kinase" title="Janus kinase">JAK</a><br /><small>(<a href="/wiki/Janus_kinase_inhibitor" title="Janus kinase inhibitor">inhibitors</a>)</small></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/JAK1" class="mw-redirect" title="JAK1">JAK1</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abrocitinib" title="Abrocitinib">Abrocitinib</a></li> <li><a href="/wiki/Baricitinib" title="Baricitinib">Baricitinib</a></li> <li><a href="/wiki/Deuruxolitinib" title="Deuruxolitinib">Deuruxolitinib</a></li> <li><a href="/wiki/Filgotinib" title="Filgotinib">Filgotinib</a></li> <li><a href="/wiki/Momelotinib" title="Momelotinib">Momelotinib</a></li> <li><a href="/wiki/Oclacitinib" title="Oclacitinib">Oclacitinib</a></li> <li><a href="/wiki/Peficitinib" title="Peficitinib">Peficitinib</a></li> <li><a href="/wiki/Ruxolitinib" title="Ruxolitinib">Ruxolitinib</a></li> <li><a href="/wiki/Tofacitinib" title="Tofacitinib">Tofacitinib (tasocitinib)</a></li> <li><a href="/wiki/Upadacitinib" title="Upadacitinib">Upadacitinib</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/JAK2" class="mw-redirect" title="JAK2">JAK2</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Atiprimod" title="Atiprimod">Atiprimod</a></li> <li><a href="/w/index.php?title=AZD-1480&action=edit&redlink=1" class="new" title="AZD-1480 (page does not exist)">AZD-1480</a></li> <li><a href="/wiki/Baricitinib" title="Baricitinib">Baricitinib</a></li> <li><a href="/wiki/CHZ868" title="CHZ868">CHZ868</a></li> <li><a href="/wiki/Cucurbitacin_I" class="mw-redirect" title="Cucurbitacin I">Cucurbitacin I (elatericin B, JSI-124)</a></li> <li><a href="/wiki/CYT387" class="mw-redirect" title="CYT387">CYT387</a></li> <li><a href="/wiki/Deuruxolitinib" title="Deuruxolitinib">Deuruxolitinib</a></li> <li><a href="/wiki/Lestaurtinib" title="Lestaurtinib">Lestaurtinib</a></li> <li><a href="/w/index.php?title=NSC-7908&action=edit&redlink=1" class="new" title="NSC-7908 (page does not exist)">NSC-7908</a></li> <li><a href="/w/index.php?title=NSC-33994&action=edit&redlink=1" class="new" title="NSC-33994 (page does not exist)">NSC-33994</a></li> <li><a href="/wiki/Pacritinib" title="Pacritinib">Pacritinib</a></li> <li><a href="/wiki/Peficitinib" title="Peficitinib">Peficitinib</a></li> <li><a href="/wiki/Ruxolitinib" title="Ruxolitinib">Ruxolitinib</a></li> <li><a href="/w/index.php?title=SD-1008&action=edit&redlink=1" class="new" title="SD-1008 (page does not exist)">SD-1008</a></li> <li><a href="/wiki/Tofacitinib" title="Tofacitinib">Tofacitinib (tasocitinib)</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/JAK3" class="mw-redirect" title="JAK3">JAK3</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Cercosporamide&action=edit&redlink=1" class="new" title="Cercosporamide (page does not exist)">Cercosporamide</a></li> <li><a href="/wiki/Decernotinib" title="Decernotinib">Decernotinib (VX-509)</a></li> <li><a href="/wiki/Peficitinib" title="Peficitinib">Peficitinib</a></li> <li><a href="/wiki/Ritlecitinib" title="Ritlecitinib">Ritlecitinib</a></li> <li><a href="/w/index.php?title=TCS-21311&action=edit&redlink=1" 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</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Others</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Additional cytokines:</i> <a href="/wiki/Cardiotrophin_1" title="Cardiotrophin 1">Cardiotrophin 1 (CT-1)</a></li> <li><a href="/wiki/FMS-like_tyrosine_kinase_3_ligand" title="FMS-like tyrosine kinase 3 ligand">FMS-like tyrosine kinase 3 ligand (FLT3L)</a></li> <li><a href="/wiki/Leukemia_inhibitory_factor" title="Leukemia inhibitory factor">Leukemia/leukocyte inhibitory factor (LIF)</a></li> <li><a href="/wiki/Oncostatin_M" title="Oncostatin M">Oncostatin M (OSM)</a></li> <li><a href="/wiki/Thymic_stromal_lymphopoietin" title="Thymic stromal lymphopoietin">Thymic stromal lymphopoietin (TSLP)</a></li></ul> <ul><li><i>Additional cytokine receptor modulators:</i> <a 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