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Hamida Hamdi - Academia.edu

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u-displayNone">less</div></div></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="67234001" href="https://www.academia.edu/Documents/in/Cadmium"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{&quot;inMailer&quot;:false,&quot;i18nLocale&quot;:&quot;en&quot;,&quot;i18nDefaultLocale&quot;:&quot;en&quot;,&quot;href&quot;:&quot;https://independent.academia.edu/HamidaHamdi&quot;,&quot;location&quot;:&quot;/HamidaHamdi&quot;,&quot;scheme&quot;:&quot;https&quot;,&quot;host&quot;:&quot;independent.academia.edu&quot;,&quot;port&quot;:null,&quot;pathname&quot;:&quot;/HamidaHamdi&quot;,&quot;search&quot;:null,&quot;httpAcceptLanguage&quot;:null,&quot;serverSide&quot;:false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" 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class="profile--tab_heading_container">Papers by Hamida Hamdi</h3></div><div class="js-work-strip profile--work_container" data-work-id="111872479"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111872479/GENOTOXIC_AND_MUTAGENIC_STUDIES_OF_THE_ANTIEPILEPTIC_DRUG_LEVETIRACETAM_IN_PREGNANT_RATS_AND_THEIR_FETUSES"><img alt="Research paper thumbnail of GENOTOXIC AND MUTAGENIC STUDIES OF THE ANTIEPILEPTIC DRUG LEVETIRACETAM IN PREGNANT RATS AND THEIR FETUSES" class="work-thumbnail" src="https://attachments.academia-assets.com/109277622/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111872479/GENOTOXIC_AND_MUTAGENIC_STUDIES_OF_THE_ANTIEPILEPTIC_DRUG_LEVETIRACETAM_IN_PREGNANT_RATS_AND_THEIR_FETUSES">GENOTOXIC AND MUTAGENIC STUDIES OF THE ANTIEPILEPTIC DRUG LEVETIRACETAM IN PREGNANT RATS AND THEIR FETUSES</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/InternationalJournalofPharmacyandPharmaceuticalSciencesIJPPS">International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HamidaHamdi">Hamida Hamdi</a></span></div><div class="wp-workCard_item"><span>International Journal of Pharmacy and Pharmaceutical Sciences</span><span>, Feb 1, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therap...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therapy in adult patients with partial-onset seizures, and used as monotherapy treatment during pregnancy. However, very few, if none, investigations have been focused on LEV neurotoxicity or hepatotoxicity at the molecular level. This study aimed to evaluate the genotoxic and mutagenic potential of LEV, in liver and brain tissues of treated pregnant rats and their fetuses during pregnancy. Methods: LEV was administered to pregnant female albino rats at doses 300 and 600 mg/kg b. w, from gestation days 5-18. Comet assay, DNA fragmentation were performed for detection of DNA damage. Single-stranded conformation polymorphism (SSCP) followed by DNA sequencing were accomplished for detecting possible mutagenicity. Results: Administration of the two tested doses of LEV resulted in a significant increase of DNA damage as detected by alkaline Comet assay, and an appearance of both apoptotic laddered and smeared DNA in the tissues tested. Moreover, a significant incidence of mutations in exon 2 and 3 of Harvey rat sarcoma viral oncogene (HRAS) gene, were detected in fetal liver and brain tissues respectively, using single-stranded conformation polymorphism (SSCP) and were confirmed by DNA sequencing. Conclusion: Maternal and fetal DNA damage induced by LEV was evidenced in our study, even at the commonly used therapeutic dose (300 mg/kg), and thus these side effects should be considered when using LEV for long-term during pregnancy.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="08d738c8cb3a90b49c59c3e0adefdfdd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:109277622,&quot;asset_id&quot;:111872479,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/109277622/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111872479"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111872479"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111872479; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=111872479]").text(description); $(".js-view-count[data-work-id=111872479]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 111872479; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='111872479']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 111872479, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "08d738c8cb3a90b49c59c3e0adefdfdd" } } $('.js-work-strip[data-work-id=111872479]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":111872479,"title":"GENOTOXIC AND MUTAGENIC STUDIES OF THE ANTIEPILEPTIC DRUG LEVETIRACETAM IN PREGNANT RATS AND THEIR FETUSES","translated_title":"","metadata":{"issue":"2","volume":"8","abstract":"Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therapy in adult patients with partial-onset seizures, and used as monotherapy treatment during pregnancy. However, very few, if none, investigations have been focused on LEV neurotoxicity or hepatotoxicity at the molecular level. This study aimed to evaluate the genotoxic and mutagenic potential of LEV, in liver and brain tissues of treated pregnant rats and their fetuses during pregnancy. Methods: LEV was administered to pregnant female albino rats at doses 300 and 600 mg/kg b. w, from gestation days 5-18. Comet assay, DNA fragmentation were performed for detection of DNA damage. Single-stranded conformation polymorphism (SSCP) followed by DNA sequencing were accomplished for detecting possible mutagenicity. Results: Administration of the two tested doses of LEV resulted in a significant increase of DNA damage as detected by alkaline Comet assay, and an appearance of both apoptotic laddered and smeared DNA in the tissues tested. 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class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111154358/Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects"><img alt="Research paper thumbnail of Morphology of the lips, cheeks, and the hard palate of the Egyptian water buffalo (Bubalus bubalis): a focus on histological, histochemical, and ultrastructural aspects" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111154358/Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects">Morphology of the lips, cheeks, and the hard palate of the Egyptian water buffalo (Bubalus bubalis): a focus on histological, histochemical, and ultrastructural aspects</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. A...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. Aims: The current investigation was focused on describing the morphology of the lip, cheek, and palate. Methods: Our study included the gross, light, and electron microscopic examinations of ten heads of the Egyptian water buffalos. Results: The nasolabial plate surface carried numerous scales of keratinized epithelium. Internal labial surface and labial mucocutaneous junctions were covered with stratified squamous keratinized epithelium. Two types of hair follicles in the dermis included ordinary and cavernous types characterized by cavernous space. The conical papillae on the internal aspect of the oral commissure were projected from the mucous membrane. Seromucous glands were occasionally observed under the oral mucous membrane of the commissure and gave positive PAS and AB. Conical papillae density on the inner cheek surface had some variations: the rostral part had large papillae, while the dorsal part had numerous papillae than the ventral part, the caudal part had a smaller number of papillae, while the middle part was devoid of papillae. Parotid duct opening in the buccal vestibule was without papillae. Conical papillae had two surfaces; the rostral surface was highly keratinized than the caudal one. The buccal gland was a compound tubuloacinar mixed (mucoserous) gland and mucus acini only reacted to PAS and AB. The oral surface of palatine rugae was covered with highly keratinized epithelium than the aboral surface. Palatine glands showed PAS and AB positive. Conclusion: The result describes the relationship between the available food particles, environmental conditions and the lip, cheek, and palate appearance, and structure.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111154358"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111154358"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111154358; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=111154358]").text(description); $(".js-view-count[data-work-id=111154358]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 111154358; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='111154358']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 111154358, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=111154358]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":111154358,"title":"Morphology of the lips, cheeks, and the hard palate of the Egyptian water buffalo (Bubalus bubalis): a focus on histological, histochemical, and ultrastructural aspects","translated_title":"","metadata":{"abstract":"Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. Aims: The current investigation was focused on describing the morphology of the lip, cheek, and palate. Methods: Our study included the gross, light, and electron microscopic examinations of ten heads of the Egyptian water buffalos. Results: The nasolabial plate surface carried numerous scales of keratinized epithelium. Internal labial surface and labial mucocutaneous junctions were covered with stratified squamous keratinized epithelium. Two types of hair follicles in the dermis included ordinary and cavernous types characterized by cavernous space. The conical papillae on the internal aspect of the oral commissure were projected from the mucous membrane. Seromucous glands were occasionally observed under the oral mucous membrane of the commissure and gave positive PAS and AB. Conical papillae density on the inner cheek surface had some variations: the rostral part had large papillae, while the dorsal part had numerous papillae than the ventral part, the caudal part had a smaller number of papillae, while the middle part was devoid of papillae. Parotid duct opening in the buccal vestibule was without papillae. Conical papillae had two surfaces; the rostral surface was highly keratinized than the caudal one. The buccal gland was a compound tubuloacinar mixed (mucoserous) gland and mucus acini only reacted to PAS and AB. The oral surface of palatine rugae was covered with highly keratinized epithelium than the aboral surface. Palatine glands showed PAS and AB positive. Conclusion: The result describes the relationship between the available food particles, environmental conditions and the lip, cheek, and palate appearance, and structure.","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"PubMed"},"translated_abstract":"Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. Aims: The current investigation was focused on describing the morphology of the lip, cheek, and palate. Methods: Our study included the gross, light, and electron microscopic examinations of ten heads of the Egyptian water buffalos. Results: The nasolabial plate surface carried numerous scales of keratinized epithelium. Internal labial surface and labial mucocutaneous junctions were covered with stratified squamous keratinized epithelium. Two types of hair follicles in the dermis included ordinary and cavernous types characterized by cavernous space. The conical papillae on the internal aspect of the oral commissure were projected from the mucous membrane. Seromucous glands were occasionally observed under the oral mucous membrane of the commissure and gave positive PAS and AB. Conical papillae density on the inner cheek surface had some variations: the rostral part had large papillae, while the dorsal part had numerous papillae than the ventral part, the caudal part had a smaller number of papillae, while the middle part was devoid of papillae. Parotid duct opening in the buccal vestibule was without papillae. Conical papillae had two surfaces; the rostral surface was highly keratinized than the caudal one. The buccal gland was a compound tubuloacinar mixed (mucoserous) gland and mucus acini only reacted to PAS and AB. The oral surface of palatine rugae was covered with highly keratinized epithelium than the aboral surface. Palatine glands showed PAS and AB positive. Conclusion: The result describes the relationship between the available food particles, environmental conditions and the lip, cheek, and palate appearance, and structure.","internal_url":"https://www.academia.edu/111154358/Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects","translated_internal_url":"","created_at":"2023-12-11T07:36:22.585-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":54589,"name":"Anatomy","url":"https://www.academia.edu/Documents/in/Anatomy"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":767308,"name":"Cheek Teeth","url":"https://www.academia.edu/Documents/in/Cheek_Teeth"},{"id":2132576,"name":"Cheek","url":"https://www.academia.edu/Documents/in/Cheek"}],"urls":[{"id":36888452,"url":"https://pubmed.ncbi.nlm.nih.gov/35126537"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="111154247"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111154247/Larval_cestodes_infecting_commercial_fish_of_Alexandria_coast_along_the_Mediterranean_Sea_morphology_and_phylogeny"><img alt="Research paper thumbnail of Larval cestodes infecting commercial fish of Alexandria coast along the Mediterranean Sea: morphology and phylogeny" class="work-thumbnail" src="https://attachments.academia-assets.com/108760973/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111154247/Larval_cestodes_infecting_commercial_fish_of_Alexandria_coast_along_the_Mediterranean_Sea_morphology_and_phylogeny">Larval cestodes infecting commercial fish of Alexandria coast along the Mediterranean Sea: morphology and phylogeny</a></div><div class="wp-workCard_item"><span>Revista Brasileira de Parasitologia Veterinária</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Members of the order Trypanorhyncha are cestode parasites that are frequently found infecting the...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Members of the order Trypanorhyncha are cestode parasites that are frequently found infecting the muscles of several marine fish species, affecting fish health and resulting in consumers’ rejection. Seventy–five specimens of marine fish were freshly caught from boat landing sites at the Alexandria coast along the Mediterranean Sea in Egypt, including two Carangids, the greater amberjack Seriola dumerili and the gulley jack Pseudocarans dentex; two Serranids, the Haifa grouper Epinephelus haifensis and the mottled grouper Mycteroperca rubra. Forty-five fish were infected; the infection was recorded as blastocysts embedded in fish flesh. Blastocysts were isolated and ruptured; the generated plerocerci were described morphologically, where, four different species were recovered; Callitetrarhynchus gracilis, Callitetrarhynchus speciosus, Protogrillotia zerbiae, and Grillotia brayi. The taxonomic position of these parasites was justified by multiple-sequence alignment and a phylogenetic ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d581fbccb01f12e3701ae6279a15d4e7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:108760973,&quot;asset_id&quot;:111154247,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/108760973/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111154247"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111154247"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111154247; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=111154247]").text(description); $(".js-view-count[data-work-id=111154247]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 111154247; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='111154247']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 111154247, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "d581fbccb01f12e3701ae6279a15d4e7" } } $('.js-work-strip[data-work-id=111154247]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":111154247,"title":"Larval cestodes infecting commercial fish of Alexandria coast along the Mediterranean Sea: morphology and phylogeny","translated_title":"","metadata":{"abstract":"Members of the order Trypanorhyncha are cestode parasites that are frequently found infecting the muscles of several marine fish species, affecting fish health and resulting in consumers’ rejection. Seventy–five specimens of marine fish were freshly caught from boat landing sites at the Alexandria coast along the Mediterranean Sea in Egypt, including two Carangids, the greater amberjack Seriola dumerili and the gulley jack Pseudocarans dentex; two Serranids, the Haifa grouper Epinephelus haifensis and the mottled grouper Mycteroperca rubra. Forty-five fish were infected; the infection was recorded as blastocysts embedded in fish flesh. Blastocysts were isolated and ruptured; the generated plerocerci were described morphologically, where, four different species were recovered; Callitetrarhynchus gracilis, Callitetrarhynchus speciosus, Protogrillotia zerbiae, and Grillotia brayi. The taxonomic position of these parasites was justified by multiple-sequence alignment and a phylogenetic ...","publisher":"FapUNIFESP (SciELO)","publication_name":"Revista Brasileira de Parasitologia Veterinária"},"translated_abstract":"Members of the order Trypanorhyncha are cestode parasites that are frequently found infecting the muscles of several marine fish species, affecting fish health and resulting in consumers’ rejection. Seventy–five specimens of marine fish were freshly caught from boat landing sites at the Alexandria coast along the Mediterranean Sea in Egypt, including two Carangids, the greater amberjack Seriola dumerili and the gulley jack Pseudocarans dentex; two Serranids, the Haifa grouper Epinephelus haifensis and the mottled grouper Mycteroperca rubra. Forty-five fish were infected; the infection was recorded as blastocysts embedded in fish flesh. Blastocysts were isolated and ruptured; the generated plerocerci were described morphologically, where, four different species were recovered; Callitetrarhynchus gracilis, Callitetrarhynchus speciosus, Protogrillotia zerbiae, and Grillotia brayi. The taxonomic position of these parasites was justified by multiple-sequence alignment and a phylogenetic ...","internal_url":"https://www.academia.edu/111154247/Larval_cestodes_infecting_commercial_fish_of_Alexandria_coast_along_the_Mediterranean_Sea_morphology_and_phylogeny","translated_internal_url":"","created_at":"2023-12-11T07:35:05.083-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108760973,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108760973/thumbnails/1.jpg","file_name":"scielo.pdf","download_url":"https://www.academia.edu/attachments/108760973/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Larval_cestodes_infecting_commercial_fis.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108760973/scielo-libre.pdf?1702309846=\u0026response-content-disposition=attachment%3B+filename%3DLarval_cestodes_infecting_commercial_fis.pdf\u0026Expires=1732781320\u0026Signature=Q5AcerXNNmC0nCO9RNh4pUyapcz9BhTHTnR41lo6e9mRXS3XAXEjAZ2gVWOVtAcSMcKiDxIGUKPILMJORlNzDnSnP9krLrWarr-iIlsVpOX-wwSAP1jg7chjKt5gtWjZSdk0Hf3t6zFjD4EDmwndkObTLhItS9FoSNJfNahcSGv7iRL8v3mseTNh1DykYQVEWSH3gXKWuIw5tgMF0SA-Vd1mOKbRRlEmkQmCx-HiLbYCCXHWF1qiArGaiGs-fWXXYj5o3N3IIuo6td-wT4xNEazSYWJ-8POOWX-UYItc1LBJC-fKgWZSfaai7B8fmKCk1FFCepsWB1s7jq~4BELmwA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Larval_cestodes_infecting_commercial_fish_of_Alexandria_coast_along_the_Mediterranean_Sea_morphology_and_phylogeny","translated_slug":"","page_count":14,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[{"id":108760973,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108760973/thumbnails/1.jpg","file_name":"scielo.pdf","download_url":"https://www.academia.edu/attachments/108760973/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Larval_cestodes_infecting_commercial_fis.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108760973/scielo-libre.pdf?1702309846=\u0026response-content-disposition=attachment%3B+filename%3DLarval_cestodes_infecting_commercial_fis.pdf\u0026Expires=1732781320\u0026Signature=Q5AcerXNNmC0nCO9RNh4pUyapcz9BhTHTnR41lo6e9mRXS3XAXEjAZ2gVWOVtAcSMcKiDxIGUKPILMJORlNzDnSnP9krLrWarr-iIlsVpOX-wwSAP1jg7chjKt5gtWjZSdk0Hf3t6zFjD4EDmwndkObTLhItS9FoSNJfNahcSGv7iRL8v3mseTNh1DykYQVEWSH3gXKWuIw5tgMF0SA-Vd1mOKbRRlEmkQmCx-HiLbYCCXHWF1qiArGaiGs-fWXXYj5o3N3IIuo6td-wT4xNEazSYWJ-8POOWX-UYItc1LBJC-fKgWZSfaai7B8fmKCk1FFCepsWB1s7jq~4BELmwA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":173285,"name":"Fishery","url":"https://www.academia.edu/Documents/in/Fishery"},{"id":299367,"name":"Serranidae","url":"https://www.academia.edu/Documents/in/Serranidae"},{"id":449981,"name":"Grouper","url":"https://www.academia.edu/Documents/in/Grouper"},{"id":1785470,"name":"Epinephelus","url":"https://www.academia.edu/Documents/in/Epinephelus"}],"urls":[{"id":36888364,"url":"http://www.scielo.br/scielo.php?script=sci_pdf\u0026pid=S1984-29612022000200309\u0026tlng=en"}]}, dispatcherData: dispatcherData }); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="102721215"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/102721215/Characterization_and_Biological_Studies_of_Synthesized_Titanium_Dioxide_Nanoparticles_from_Leaf_Extract_of_Juniperus_phoenicea_L_Growing_in_Taif_Region_Saudi_Arabia"><img alt="Research paper thumbnail of Characterization and Biological Studies of Synthesized Titanium Dioxide Nanoparticles from Leaf Extract of Juniperus phoenicea (L.) Growing in Taif Region, Saudi Arabia" class="work-thumbnail" src="https://attachments.academia-assets.com/102915795/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/102721215/Characterization_and_Biological_Studies_of_Synthesized_Titanium_Dioxide_Nanoparticles_from_Leaf_Extract_of_Juniperus_phoenicea_L_Growing_in_Taif_Region_Saudi_Arabia">Characterization and Biological Studies of Synthesized Titanium Dioxide Nanoparticles from Leaf Extract of Juniperus phoenicea (L.) Growing in Taif Region, Saudi Arabia</a></div><div class="wp-workCard_item"><span>Processes</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Green synthesis of metal nanoparticles in nanosized form has acquired great interest in the area ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Green synthesis of metal nanoparticles in nanosized form has acquired great interest in the area of nanomedicine as an environmentally friendly and cost-effective alternative compared to other chemical and physical methods. This study deals with the eco-friendly green synthesis of titanium dioxide nanoparticles (TiO2 NPs) utilizing Juniperus phoenicea leaf extract and their characterization. The biosynthesis of TiO2 NPs was completed in 3 h and confirmed by UV-Vis spectroscopy, a strong band at 205.4 nm distinctly revealed the formation of NPs. Transmissions electron microscopy (TEM) analysis showed the synthesized TiO2 NPs are spherical in shape, with a diameter in a range of 10–30 nm. The XRD major peak at 27.1° congruent with the (110) lattice plane of tetragonal rutile TiO2 phase. Dynamic light scattering (DLS) analysis revealed synthesized TiO2 NPs average particle size (hydrodynamic diameter) of (74.8 ± 0.649) nm. Fourier transmission infrared (FTIR) revealed the bioactive com...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7679932fa6f31cfb00734ea80563d86a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:102915795,&quot;asset_id&quot;:102721215,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/102915795/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="102721215"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="102721215"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 102721215; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=102721215]").text(description); $(".js-view-count[data-work-id=102721215]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 102721215; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='102721215']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 102721215, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7679932fa6f31cfb00734ea80563d86a" } } $('.js-work-strip[data-work-id=102721215]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":102721215,"title":"Characterization and Biological Studies of Synthesized Titanium Dioxide Nanoparticles from Leaf Extract of Juniperus phoenicea (L.) 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100092392"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100092392/Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves"><img alt="Research paper thumbnail of Antimicrobial and Wound Healing Potentials of Vitis Vitigenia Leaves" class="work-thumbnail" src="https://attachments.academia-assets.com/101008816/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100092392/Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves">Antimicrobial and Wound Healing Potentials of Vitis Vitigenia Leaves</a></div><div class="wp-workCard_item"><span>American Journal of Pharmacology and Toxicology</span><span>, 2011</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="66a2c5fc642300ca85e79ce05c75ce69" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:101008816,&quot;asset_id&quot;:100092392,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/101008816/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100092392"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100092392"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100092392; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "66a2c5fc642300ca85e79ce05c75ce69" } } $('.js-work-strip[data-work-id=100092392]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100092392,"title":"Antimicrobial and Wound Healing Potentials of Vitis Vitigenia Leaves","translated_title":"","metadata":{"publisher":"Science Publications","grobid_abstract":"Problem statement: The investigation for possible antimicrobial and wound healing activity of ethanolic and aqueous extracts of V. Vitigenia L. leaves were performed. The antimicrobial activity of extract was studied against the 8 bacterial and 2 fungal strains using agar cup plate method. Approach: The wound healing effect of both the extract of V. Vitigenia L. leaves were evaluated by incision and excision model in rats. The incision model was assessed by the breaking strength and excision model by % wound contraction and period of Epithelialization. Results: The results showed that both the extracts exhibited significant antimicrobial activity against all the tested microorganisms and have significant wound healing activity as evident from the breaking strength; % wound contraction and period of epithelialization. Conclusion: Therefore, the present study provides a scientific rationale for the traditional use of V. Vitigenia L. in the management of wounds.","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"American Journal of Pharmacology and Toxicology","grobid_abstract_attachment_id":101008816},"translated_abstract":null,"internal_url":"https://www.academia.edu/100092392/Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves","translated_internal_url":"","created_at":"2023-04-12T03:09:18.799-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101008816,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101008816/thumbnails/1.jpg","file_name":"ajptsp.2011.119.123.pdf","download_url":"https://www.academia.edu/attachments/101008816/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Antimicrobial_and_Wound_Healing_Potentia.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101008816/ajptsp.2011.119.123-libre.pdf?1681297675=\u0026response-content-disposition=attachment%3B+filename%3DAntimicrobial_and_Wound_Healing_Potentia.pdf\u0026Expires=1732781320\u0026Signature=R89LByu9jg6DpN5GtmmF5cuBnR2YZEHXc2Tu2Opi1HJovNuIvZFrRQ6dBLp23ZdOjNMztRoAxg7JMqMfeAYYx3KtWhz42jcR7f4fVg-Z0c4DUFRRd4MnuPcZJ5yTdAwDRzK7NSVEUUP1vnELAu3qRyoemA64Q83FFLMyskqos6qFJq6fDvv5l7j1QAIeYmB81~SHRnD8hBMu~9sp6WflWsQLGHE6m1OO~Z-L7DMI5-Xquuf5kLDTXLOaPTSdDTaBSpBbu32SyQ9h~N09SiW4WtWV0889UwiksbsvTAVQrDQR~z3-7pzxy2qp3LBlwDkj0jEr0mSGBnNai2VYt3opFQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[{"id":101008816,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101008816/thumbnails/1.jpg","file_name":"ajptsp.2011.119.123.pdf","download_url":"https://www.academia.edu/attachments/101008816/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Antimicrobial_and_Wound_Healing_Potentia.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101008816/ajptsp.2011.119.123-libre.pdf?1681297675=\u0026response-content-disposition=attachment%3B+filename%3DAntimicrobial_and_Wound_Healing_Potentia.pdf\u0026Expires=1732781320\u0026Signature=R89LByu9jg6DpN5GtmmF5cuBnR2YZEHXc2Tu2Opi1HJovNuIvZFrRQ6dBLp23ZdOjNMztRoAxg7JMqMfeAYYx3KtWhz42jcR7f4fVg-Z0c4DUFRRd4MnuPcZJ5yTdAwDRzK7NSVEUUP1vnELAu3qRyoemA64Q83FFLMyskqos6qFJq6fDvv5l7j1QAIeYmB81~SHRnD8hBMu~9sp6WflWsQLGHE6m1OO~Z-L7DMI5-Xquuf5kLDTXLOaPTSdDTaBSpBbu32SyQ9h~N09SiW4WtWV0889UwiksbsvTAVQrDQR~z3-7pzxy2qp3LBlwDkj0jEr0mSGBnNai2VYt3opFQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":220036,"name":"Antimicrobial","url":"https://www.academia.edu/Documents/in/Antimicrobial"},{"id":772284,"name":"Agar","url":"https://www.academia.edu/Documents/in/Agar"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96990401"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96990401/Protective_Effect_of_Annona_muricata_Linn_Fruit_Pulp_Lyophilized_Powder_against_Paracetamol_Induced_Redox_Imbalance_and_Hepatotoxicity_in_Rats"><img alt="Research paper thumbnail of Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats" class="work-thumbnail" src="https://attachments.academia-assets.com/98735858/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96990401/Protective_Effect_of_Annona_muricata_Linn_Fruit_Pulp_Lyophilized_Powder_against_Paracetamol_Induced_Redox_Imbalance_and_Hepatotoxicity_in_Rats">Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats</a></div><div class="wp-workCard_item"><span>Processes</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated f...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen (APAP). Male Sprague Dawley rats were orally pre-treated for 15 days with A. muricata lyophilized fruit pulp powder at low (1 g/kg b.wt) and high doses (2 g/kg b.wt). Silymarin (100 mg/kg) was administered as the standard drug. Hepatotoxicity was induced using APAP, in a single oral administration of 2.5 g/kg body weight dosage on the 15th day. Aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) were elevated in the APAP group but were found to be significantly reduced in the pre-treated groups in a dose-dependent manner. APAP administration brought down the serum total protein and albumin levels significantly. The activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase were reduced in the APAP administration; further, the reduced glutathione pool in ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ce5ad42e7291f2bd9f85b7f452dfa1a0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:98735858,&quot;asset_id&quot;:96990401,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/98735858/download_file?st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96990401"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96990401"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96990401; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96990401]").text(description); $(".js-view-count[data-work-id=96990401]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96990401; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96990401']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96990401, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ce5ad42e7291f2bd9f85b7f452dfa1a0" } } $('.js-work-strip[data-work-id=96990401]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96990401,"title":"Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats","translated_title":"","metadata":{"abstract":"In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen (APAP). Male Sprague Dawley rats were orally pre-treated for 15 days with A. muricata lyophilized fruit pulp powder at low (1 g/kg b.wt) and high doses (2 g/kg b.wt). Silymarin (100 mg/kg) was administered as the standard drug. Hepatotoxicity was induced using APAP, in a single oral administration of 2.5 g/kg body weight dosage on the 15th day. Aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) were elevated in the APAP group but were found to be significantly reduced in the pre-treated groups in a dose-dependent manner. APAP administration brought down the serum total protein and albumin levels significantly. The activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase were reduced in the APAP administration; further, the reduced glutathione pool in ...","publisher":"MDPI AG","publication_name":"Processes"},"translated_abstract":"In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen (APAP). Male Sprague Dawley rats were orally pre-treated for 15 days with A. muricata lyophilized fruit pulp powder at low (1 g/kg b.wt) and high doses (2 g/kg b.wt). Silymarin (100 mg/kg) was administered as the standard drug. Hepatotoxicity was induced using APAP, in a single oral administration of 2.5 g/kg body weight dosage on the 15th day. Aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) were elevated in the APAP group but were found to be significantly reduced in the pre-treated groups in a dose-dependent manner. APAP administration brought down the serum total protein and albumin levels significantly. 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(Amaryllidaceae), como potencial protetor contra Anisakis spp. Infecção tipo II (L3) (Nematoda) em ratos Wistar" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96990400/O_%C3%B3leo_de_alho_Allium_sativum_L_Amaryllidaceae_como_potencial_protetor_contra_Anisakis_spp_Infec%C3%A7%C3%A3o_tipo_II_L3_Nematoda_em_ratos_Wistar">O óleo de alho, Allium sativum L. (Amaryllidaceae), como potencial protetor contra Anisakis spp. Infecção tipo II (L3) (Nematoda) em ratos Wistar</a></div><div class="wp-workCard_item"><span>Revista Brasileira De Parasitologia Veterinaria</span><span>, 2021</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96990400"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96990400"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96990400; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96990400]").text(description); $(".js-view-count[data-work-id=96990400]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96990400; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96990400']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96990400, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=96990400]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96990400,"title":"O óleo de alho, Allium sativum L. 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The pl...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Curcuma species are widely used as a food additive and also in various medicinal purposes. The plant is a rich source of essential oil and is predominantly extracted from the rhizomes. On the other hand, the leaves of the plants are usually considered as an agrowaste. The valorization of these Curcuma leaf wastes into essential oils is becoming accepted globally. In the present study, we aim to extract essential oils from the leaves of Curcuma longa (LEO), C. aromatica (REO), and C. anguistifolia (NEO). The chemical composition of these essential oils was analyzed by GC-MS. Free radical scavenging properties were evaluated against the radical sources, including DPPH, ABTS, and hydrogen peroxide. The antibacterial activity was assessed by the disc diffusion method and Minimum inhibitory concentration analysis against Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica) bacteria. Results identified the compounds α-p...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="113f9726981abf055619a5dd5a469aaa" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:98735848,&quot;asset_id&quot;:96990387,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/98735848/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96990387"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96990387"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96990387; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96990387]").text(description); $(".js-view-count[data-work-id=96990387]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96990387; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96990387']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96990387, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "113f9726981abf055619a5dd5a469aaa" } } $('.js-work-strip[data-work-id=96990387]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96990387,"title":"Chemical Composition and Biological Activities of the Leaf Essential Oils of Curcuma longa, Curcuma aromatica and Curcuma angustifolia","translated_title":"","metadata":{"abstract":"Curcuma species are widely used as a food additive and also in various medicinal purposes. 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class="wp-workCard_item"><span>Journal of Biochemical and Molecular Toxicology</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="88102755"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="88102755"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 88102755; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); 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href="https://www.academia.edu/88102754/Chemical_Composition_and_Antioxidant_Antiviral_Antifungal_Antibacterial_and_Anticancer_Potentials_of_Opuntia_ficus_indica_Seed_Oil"><img alt="Research paper thumbnail of Chemical Composition and Antioxidant, Antiviral, Antifungal, Antibacterial and Anticancer Potentials of Opuntia ficus-indica Seed Oil" class="work-thumbnail" src="https://attachments.academia-assets.com/92144576/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/88102754/Chemical_Composition_and_Antioxidant_Antiviral_Antifungal_Antibacterial_and_Anticancer_Potentials_of_Opuntia_ficus_indica_Seed_Oil">Chemical Composition and Antioxidant, Antiviral, Antifungal, Antibacterial and Anticancer Potentials of Opuntia ficus-indica Seed Oil</a></div><div class="wp-workCard_item"><span>Molecules</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Opuntia ficus-indica (OFI) is a cactus that is widely cultivated in the Kingdom of Saudi Arabia e...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Opuntia ficus-indica (OFI) is a cactus that is widely cultivated in the Kingdom of Saudi Arabia especially in the Taif region due to its favorable weather for growing, and it has benefits as a food and traditional medicine. The aim of the current study was to chemically characterize Opuntia ficus-indica seed oil from Taif, Kingdom of Saudi Arabia, using GC-MS and HPLC analysis and evaluate its antioxidant, antiviral, antifungal, antibacterial and anticancer activities. Linolenic acid was the dominating fatty acid in OFI oil, followed by oleic acid, linoleic acid, palmitic acid and stearic acid. Total tocopherol (α-, β-, Ɣ-tocopherol) was found to be 24.02 μg/mL. Campesterol was the main phytosterol, followed by γ- &amp; β -sitosterol, and Stigmasterol. The phenolic components scored 30.5 mg gallic acid equivalent per ml of oil with 89.2% antioxidant activity (% DPPH radical inhibition) at 200 µL/mL of OFI oil. OFI oil showed an inhibition efficacy against microbial strains especially Sa...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="81710b04d5f681def173857659f07077" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:92144576,&quot;asset_id&quot;:88102754,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/92144576/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="88102754"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="88102754"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 88102754; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=88102754]").text(description); $(".js-view-count[data-work-id=88102754]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 88102754; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='88102754']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 88102754, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "81710b04d5f681def173857659f07077" } } $('.js-work-strip[data-work-id=88102754]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":88102754,"title":"Chemical Composition and Antioxidant, Antiviral, Antifungal, Antibacterial and Anticancer Potentials of Opuntia ficus-indica Seed Oil","translated_title":"","metadata":{"abstract":"Opuntia ficus-indica (OFI) is a cactus that is widely cultivated in the Kingdom of Saudi Arabia especially in the Taif region due to its favorable weather for growing, and it has benefits as a food and traditional medicine. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="12194048" id="papers"><div class="js-work-strip profile--work_container" data-work-id="111872479"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111872479/GENOTOXIC_AND_MUTAGENIC_STUDIES_OF_THE_ANTIEPILEPTIC_DRUG_LEVETIRACETAM_IN_PREGNANT_RATS_AND_THEIR_FETUSES"><img alt="Research paper thumbnail of GENOTOXIC AND MUTAGENIC STUDIES OF THE ANTIEPILEPTIC DRUG LEVETIRACETAM IN PREGNANT RATS AND THEIR FETUSES" class="work-thumbnail" src="https://attachments.academia-assets.com/109277622/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111872479/GENOTOXIC_AND_MUTAGENIC_STUDIES_OF_THE_ANTIEPILEPTIC_DRUG_LEVETIRACETAM_IN_PREGNANT_RATS_AND_THEIR_FETUSES">GENOTOXIC AND MUTAGENIC STUDIES OF THE ANTIEPILEPTIC DRUG LEVETIRACETAM IN PREGNANT RATS AND THEIR FETUSES</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/InternationalJournalofPharmacyandPharmaceuticalSciencesIJPPS">International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HamidaHamdi">Hamida Hamdi</a></span></div><div class="wp-workCard_item"><span>International Journal of Pharmacy and Pharmaceutical Sciences</span><span>, Feb 1, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therap...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therapy in adult patients with partial-onset seizures, and used as monotherapy treatment during pregnancy. However, very few, if none, investigations have been focused on LEV neurotoxicity or hepatotoxicity at the molecular level. This study aimed to evaluate the genotoxic and mutagenic potential of LEV, in liver and brain tissues of treated pregnant rats and their fetuses during pregnancy. Methods: LEV was administered to pregnant female albino rats at doses 300 and 600 mg/kg b. w, from gestation days 5-18. Comet assay, DNA fragmentation were performed for detection of DNA damage. Single-stranded conformation polymorphism (SSCP) followed by DNA sequencing were accomplished for detecting possible mutagenicity. Results: Administration of the two tested doses of LEV resulted in a significant increase of DNA damage as detected by alkaline Comet assay, and an appearance of both apoptotic laddered and smeared DNA in the tissues tested. Moreover, a significant incidence of mutations in exon 2 and 3 of Harvey rat sarcoma viral oncogene (HRAS) gene, were detected in fetal liver and brain tissues respectively, using single-stranded conformation polymorphism (SSCP) and were confirmed by DNA sequencing. Conclusion: Maternal and fetal DNA damage induced by LEV was evidenced in our study, even at the commonly used therapeutic dose (300 mg/kg), and thus these side effects should be considered when using LEV for long-term during pregnancy.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="08d738c8cb3a90b49c59c3e0adefdfdd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:109277622,&quot;asset_id&quot;:111872479,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/109277622/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111872479"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111872479"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111872479; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=111872479]").text(description); $(".js-view-count[data-work-id=111872479]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 111872479; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='111872479']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 111872479, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "08d738c8cb3a90b49c59c3e0adefdfdd" } } $('.js-work-strip[data-work-id=111872479]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":111872479,"title":"GENOTOXIC AND MUTAGENIC STUDIES OF THE ANTIEPILEPTIC DRUG LEVETIRACETAM IN PREGNANT RATS AND THEIR FETUSES","translated_title":"","metadata":{"issue":"2","volume":"8","abstract":"Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therapy in adult patients with partial-onset seizures, and used as monotherapy treatment during pregnancy. However, very few, if none, investigations have been focused on LEV neurotoxicity or hepatotoxicity at the molecular level. This study aimed to evaluate the genotoxic and mutagenic potential of LEV, in liver and brain tissues of treated pregnant rats and their fetuses during pregnancy. Methods: LEV was administered to pregnant female albino rats at doses 300 and 600 mg/kg b. w, from gestation days 5-18. Comet assay, DNA fragmentation were performed for detection of DNA damage. Single-stranded conformation polymorphism (SSCP) followed by DNA sequencing were accomplished for detecting possible mutagenicity. Results: Administration of the two tested doses of LEV resulted in a significant increase of DNA damage as detected by alkaline Comet assay, and an appearance of both apoptotic laddered and smeared DNA in the tissues tested. Moreover, a significant incidence of mutations in exon 2 and 3 of Harvey rat sarcoma viral oncogene (HRAS) gene, were detected in fetal liver and brain tissues respectively, using single-stranded conformation polymorphism (SSCP) and were confirmed by DNA sequencing. Conclusion: Maternal and fetal DNA damage induced by LEV was evidenced in our study, even at the commonly used therapeutic dose (300 mg/kg), and thus these side effects should be considered when using LEV for long-term during pregnancy.","journal_name":"International Journal of Pharmacy and Pharmaceutical Sciences","page_numbers":"82-88","publication_date":{"day":1,"month":2,"year":2016,"errors":{}},"publication_name":"International Journal of Pharmacy and Pharmaceutical Sciences"},"translated_abstract":"Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therapy in adult patients with partial-onset seizures, and used as monotherapy treatment during pregnancy. 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Moreover, a significant incidence of mutations in exon 2 and 3 of Harvey rat sarcoma viral oncogene (HRAS) gene, were detected in fetal liver and brain tissues respectively, using single-stranded conformation polymorphism (SSCP) and were confirmed by DNA sequencing. 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nilagirica (C.B. Clarke) Pamp" class="work-thumbnail" src="https://attachments.academia-assets.com/108761076/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111154365/Phytochemical_Composition_and_In_Vitro_Antioxidant_Anti_Inflammatory_Anticancer_and_Enzyme_Inhibitory_Activities_of_Artemisia_nilagirica_C_B_Clarke_Pamp">Phytochemical Composition and In Vitro Antioxidant, Anti-Inflammatory, Anticancer, and Enzyme-Inhibitory Activities of Artemisia nilagirica (C.B. 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BY","publication_date":{"day":3,"month":11,"year":2022,"errors":{}},"publication_name":"Antibiotics","grobid_abstract_attachment_id":108761072},"translated_abstract":null,"internal_url":"https://www.academia.edu/111154359/Chemical_Composition_and_Biological_Activities_of_the_Leaf_Essential_Oils_of_Curcuma_longa_Curcuma_aromatica_and_Curcuma_angustifolia","translated_internal_url":"","created_at":"2023-12-11T07:36:22.992-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":108761072,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/108761072/thumbnails/1.jpg","file_name":"pdf.pdf","download_url":"https://www.academia.edu/attachments/108761072/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Chemical_Composition_and_Biological_Acti.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/108761072/pdf-libre.pdf?1702309841=\u0026response-content-disposition=attachment%3B+filename%3DChemical_Composition_and_Biological_Acti.pdf\u0026Expires=1732781320\u0026Signature=U3urBDVp-RknM1ESZs~LvkaAl6nGqojVOzX1lMlmkMrZo1LehjTFZj02c1xY7yUYYe-40VWSaDgxBMlJCVm8GmV4pyQS1as2~yY79PNbHTJ1N31Aoq1YtkqEZmu4BB-py8Dm6vuoDU7lBhlVGmCEhFZosMXSvB1l2UVo~XQsPS8NNNCFApKhfxu9XCBoPg~8aZLses4uky2H212fvf25jaeHk5baE-LcCugrujn18BkzfnVRCx91KlrjlknGeGHWk9UB5jkiZLQRGpEpXU4yxlNhSxG-lLoZVcLF9Gogu~NNnOvCCnHM6ZgBo9F-r09PEHLtZ-yhLnhL3sUfX1Or8A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Chemical_Composition_and_Biological_Activities_of_the_Leaf_Essential_Oils_of_Curcuma_longa_Curcuma_aromatica_and_Curcuma_angustifolia","translated_slug":"","page_count":14,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida 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Science","url":"https://www.academia.edu/Documents/in/Food_Science"},{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine"},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology"},{"id":48465,"name":"Essential Oil","url":"https://www.academia.edu/Documents/in/Essential_Oil"},{"id":220036,"name":"Antimicrobial","url":"https://www.academia.edu/Documents/in/Antimicrobial"},{"id":234672,"name":"Zingiberaceae","url":"https://www.academia.edu/Documents/in/Zingiberaceae"},{"id":251655,"name":"Antibiotics","url":"https://www.academia.edu/Documents/in/Antibiotics"},{"id":290432,"name":"Antibacterial activity","url":"https://www.academia.edu/Documents/in/Antibacterial_activity"},{"id":382472,"name":"DPPH","url":"https://www.academia.edu/Documents/in/DPPH"},{"id":731133,"name":"Curcuma","url":"https://www.academia.edu/Documents/in/Curcuma"},{"id":765952,"name":"ABTS","url":"https://www.academia.edu/Documents/in/ABTS"},{"id":1120916,"name":"Camphor","url":"https://www.academia.edu/Documents/in/Camphor"},{"id":2280378,"name":"Eucalyptol","url":"https://www.academia.edu/Documents/in/Eucalyptol"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[{"id":36888453,"url":"https://www.mdpi.com/2079-6382/11/11/1547/pdf?version=1669279718"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="111154358"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111154358/Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects"><img alt="Research paper thumbnail of Morphology of the lips, cheeks, and the hard palate of the Egyptian water buffalo (Bubalus bubalis): a focus on histological, histochemical, and ultrastructural aspects" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111154358/Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects">Morphology of the lips, cheeks, and the hard palate of the Egyptian water buffalo (Bubalus bubalis): a focus on histological, histochemical, and ultrastructural aspects</a></div><div class="wp-workCard_item"><span>PubMed</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. A...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. Aims: The current investigation was focused on describing the morphology of the lip, cheek, and palate. Methods: Our study included the gross, light, and electron microscopic examinations of ten heads of the Egyptian water buffalos. Results: The nasolabial plate surface carried numerous scales of keratinized epithelium. Internal labial surface and labial mucocutaneous junctions were covered with stratified squamous keratinized epithelium. Two types of hair follicles in the dermis included ordinary and cavernous types characterized by cavernous space. The conical papillae on the internal aspect of the oral commissure were projected from the mucous membrane. Seromucous glands were occasionally observed under the oral mucous membrane of the commissure and gave positive PAS and AB. Conical papillae density on the inner cheek surface had some variations: the rostral part had large papillae, while the dorsal part had numerous papillae than the ventral part, the caudal part had a smaller number of papillae, while the middle part was devoid of papillae. Parotid duct opening in the buccal vestibule was without papillae. Conical papillae had two surfaces; the rostral surface was highly keratinized than the caudal one. The buccal gland was a compound tubuloacinar mixed (mucoserous) gland and mucus acini only reacted to PAS and AB. The oral surface of palatine rugae was covered with highly keratinized epithelium than the aboral surface. Palatine glands showed PAS and AB positive. Conclusion: The result describes the relationship between the available food particles, environmental conditions and the lip, cheek, and palate appearance, and structure.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="111154358"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="111154358"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 111154358; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=111154358]").text(description); $(".js-view-count[data-work-id=111154358]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 111154358; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='111154358']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 111154358, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=111154358]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":111154358,"title":"Morphology of the lips, cheeks, and the hard palate of the Egyptian water buffalo (Bubalus bubalis): a focus on histological, histochemical, and ultrastructural aspects","translated_title":"","metadata":{"abstract":"Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. Aims: The current investigation was focused on describing the morphology of the lip, cheek, and palate. Methods: Our study included the gross, light, and electron microscopic examinations of ten heads of the Egyptian water buffalos. Results: The nasolabial plate surface carried numerous scales of keratinized epithelium. Internal labial surface and labial mucocutaneous junctions were covered with stratified squamous keratinized epithelium. Two types of hair follicles in the dermis included ordinary and cavernous types characterized by cavernous space. The conical papillae on the internal aspect of the oral commissure were projected from the mucous membrane. Seromucous glands were occasionally observed under the oral mucous membrane of the commissure and gave positive PAS and AB. Conical papillae density on the inner cheek surface had some variations: the rostral part had large papillae, while the dorsal part had numerous papillae than the ventral part, the caudal part had a smaller number of papillae, while the middle part was devoid of papillae. Parotid duct opening in the buccal vestibule was without papillae. Conical papillae had two surfaces; the rostral surface was highly keratinized than the caudal one. The buccal gland was a compound tubuloacinar mixed (mucoserous) gland and mucus acini only reacted to PAS and AB. The oral surface of palatine rugae was covered with highly keratinized epithelium than the aboral surface. Palatine glands showed PAS and AB positive. Conclusion: The result describes the relationship between the available food particles, environmental conditions and the lip, cheek, and palate appearance, and structure.","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"PubMed"},"translated_abstract":"Background: The available data is scanty about Egyptian water buffalo lips, cheeks, and palate. Aims: The current investigation was focused on describing the morphology of the lip, cheek, and palate. Methods: Our study included the gross, light, and electron microscopic examinations of ten heads of the Egyptian water buffalos. Results: The nasolabial plate surface carried numerous scales of keratinized epithelium. Internal labial surface and labial mucocutaneous junctions were covered with stratified squamous keratinized epithelium. Two types of hair follicles in the dermis included ordinary and cavernous types characterized by cavernous space. The conical papillae on the internal aspect of the oral commissure were projected from the mucous membrane. Seromucous glands were occasionally observed under the oral mucous membrane of the commissure and gave positive PAS and AB. Conical papillae density on the inner cheek surface had some variations: the rostral part had large papillae, while the dorsal part had numerous papillae than the ventral part, the caudal part had a smaller number of papillae, while the middle part was devoid of papillae. Parotid duct opening in the buccal vestibule was without papillae. Conical papillae had two surfaces; the rostral surface was highly keratinized than the caudal one. The buccal gland was a compound tubuloacinar mixed (mucoserous) gland and mucus acini only reacted to PAS and AB. The oral surface of palatine rugae was covered with highly keratinized epithelium than the aboral surface. Palatine glands showed PAS and AB positive. Conclusion: The result describes the relationship between the available food particles, environmental conditions and the lip, cheek, and palate appearance, and structure.","internal_url":"https://www.academia.edu/111154358/Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects","translated_internal_url":"","created_at":"2023-12-11T07:36:22.585-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Morphology_of_the_lips_cheeks_and_the_hard_palate_of_the_Egyptian_water_buffalo_Bubalus_bubalis_a_focus_on_histological_histochemical_and_ultrastructural_aspects","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":54589,"name":"Anatomy","url":"https://www.academia.edu/Documents/in/Anatomy"},{"id":98939,"name":"Pubmed","url":"https://www.academia.edu/Documents/in/Pubmed"},{"id":767308,"name":"Cheek Teeth","url":"https://www.academia.edu/Documents/in/Cheek_Teeth"},{"id":2132576,"name":"Cheek","url":"https://www.academia.edu/Documents/in/Cheek"}],"urls":[{"id":36888452,"url":"https://pubmed.ncbi.nlm.nih.gov/35126537"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="111154247"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/111154247/Larval_cestodes_infecting_commercial_fish_of_Alexandria_coast_along_the_Mediterranean_Sea_morphology_and_phylogeny"><img alt="Research paper thumbnail of Larval cestodes infecting commercial fish of Alexandria coast along the Mediterranean Sea: morphology and phylogeny" class="work-thumbnail" src="https://attachments.academia-assets.com/108760973/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/111154247/Larval_cestodes_infecting_commercial_fish_of_Alexandria_coast_along_the_Mediterranean_Sea_morphology_and_phylogeny">Larval cestodes infecting commercial fish of Alexandria coast along the Mediterranean Sea: morphology and phylogeny</a></div><div class="wp-workCard_item"><span>Revista Brasileira de Parasitologia Veterinária</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Members of the order Trypanorhyncha are cestode parasites that are frequently found infecting the...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Members of the order Trypanorhyncha are cestode parasites that are frequently found infecting the muscles of several marine fish species, affecting fish health and resulting in consumers’ rejection. Seventy–five specimens of marine fish were freshly caught from boat landing sites at the Alexandria coast along the Mediterranean Sea in Egypt, including two Carangids, the greater amberjack Seriola dumerili and the gulley jack Pseudocarans dentex; two Serranids, the Haifa grouper Epinephelus haifensis and the mottled grouper Mycteroperca rubra. Forty-five fish were infected; the infection was recorded as blastocysts embedded in fish flesh. Blastocysts were isolated and ruptured; the generated plerocerci were described morphologically, where, four different species were recovered; Callitetrarhynchus gracilis, Callitetrarhynchus speciosus, Protogrillotia zerbiae, and Grillotia brayi. 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Growing in Taif Region, Saudi Arabia" class="work-thumbnail" src="https://attachments.academia-assets.com/102915795/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/102721215/Characterization_and_Biological_Studies_of_Synthesized_Titanium_Dioxide_Nanoparticles_from_Leaf_Extract_of_Juniperus_phoenicea_L_Growing_in_Taif_Region_Saudi_Arabia">Characterization and Biological Studies of Synthesized Titanium Dioxide Nanoparticles from Leaf Extract of Juniperus phoenicea (L.) Growing in Taif Region, Saudi Arabia</a></div><div class="wp-workCard_item"><span>Processes</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Green synthesis of metal nanoparticles in nanosized form has acquired great interest in the area ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Green synthesis of metal nanoparticles in nanosized form has acquired great interest in the area of nanomedicine as an environmentally friendly and cost-effective alternative compared to other chemical and physical methods. This study deals with the eco-friendly green synthesis of titanium dioxide nanoparticles (TiO2 NPs) utilizing Juniperus phoenicea leaf extract and their characterization. The biosynthesis of TiO2 NPs was completed in 3 h and confirmed by UV-Vis spectroscopy, a strong band at 205.4 nm distinctly revealed the formation of NPs. Transmissions electron microscopy (TEM) analysis showed the synthesized TiO2 NPs are spherical in shape, with a diameter in a range of 10–30 nm. The XRD major peak at 27.1° congruent with the (110) lattice plane of tetragonal rutile TiO2 phase. Dynamic light scattering (DLS) analysis revealed synthesized TiO2 NPs average particle size (hydrodynamic diameter) of (74.8 ± 0.649) nm. Fourier transmission infrared (FTIR) revealed the bioactive com...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7679932fa6f31cfb00734ea80563d86a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:102915795,&quot;asset_id&quot;:102721215,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/102915795/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="102721215"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="102721215"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 102721215; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=102721215]").text(description); $(".js-view-count[data-work-id=102721215]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 102721215; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='102721215']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 102721215, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7679932fa6f31cfb00734ea80563d86a" } } $('.js-work-strip[data-work-id=102721215]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":102721215,"title":"Characterization and Biological Studies of Synthesized Titanium Dioxide Nanoparticles from Leaf Extract of Juniperus phoenicea (L.) 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="100092392"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100092392/Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves"><img alt="Research paper thumbnail of Antimicrobial and Wound Healing Potentials of Vitis Vitigenia Leaves" class="work-thumbnail" src="https://attachments.academia-assets.com/101008816/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100092392/Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves">Antimicrobial and Wound Healing Potentials of Vitis Vitigenia Leaves</a></div><div class="wp-workCard_item"><span>American Journal of Pharmacology and Toxicology</span><span>, 2011</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="66a2c5fc642300ca85e79ce05c75ce69" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:101008816,&quot;asset_id&quot;:100092392,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/101008816/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100092392"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100092392"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100092392; 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Vitigenia L. leaves were performed. The antimicrobial activity of extract was studied against the 8 bacterial and 2 fungal strains using agar cup plate method. Approach: The wound healing effect of both the extract of V. Vitigenia L. leaves were evaluated by incision and excision model in rats. The incision model was assessed by the breaking strength and excision model by % wound contraction and period of Epithelialization. Results: The results showed that both the extracts exhibited significant antimicrobial activity against all the tested microorganisms and have significant wound healing activity as evident from the breaking strength; % wound contraction and period of epithelialization. Conclusion: Therefore, the present study provides a scientific rationale for the traditional use of V. Vitigenia L. in the management of wounds.","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"American Journal of Pharmacology and Toxicology","grobid_abstract_attachment_id":101008816},"translated_abstract":null,"internal_url":"https://www.academia.edu/100092392/Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves","translated_internal_url":"","created_at":"2023-04-12T03:09:18.799-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":101008816,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101008816/thumbnails/1.jpg","file_name":"ajptsp.2011.119.123.pdf","download_url":"https://www.academia.edu/attachments/101008816/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Antimicrobial_and_Wound_Healing_Potentia.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101008816/ajptsp.2011.119.123-libre.pdf?1681297675=\u0026response-content-disposition=attachment%3B+filename%3DAntimicrobial_and_Wound_Healing_Potentia.pdf\u0026Expires=1732781320\u0026Signature=R89LByu9jg6DpN5GtmmF5cuBnR2YZEHXc2Tu2Opi1HJovNuIvZFrRQ6dBLp23ZdOjNMztRoAxg7JMqMfeAYYx3KtWhz42jcR7f4fVg-Z0c4DUFRRd4MnuPcZJ5yTdAwDRzK7NSVEUUP1vnELAu3qRyoemA64Q83FFLMyskqos6qFJq6fDvv5l7j1QAIeYmB81~SHRnD8hBMu~9sp6WflWsQLGHE6m1OO~Z-L7DMI5-Xquuf5kLDTXLOaPTSdDTaBSpBbu32SyQ9h~N09SiW4WtWV0889UwiksbsvTAVQrDQR~z3-7pzxy2qp3LBlwDkj0jEr0mSGBnNai2VYt3opFQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Antimicrobial_and_Wound_Healing_Potentials_of_Vitis_Vitigenia_Leaves","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[{"id":101008816,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/101008816/thumbnails/1.jpg","file_name":"ajptsp.2011.119.123.pdf","download_url":"https://www.academia.edu/attachments/101008816/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Antimicrobial_and_Wound_Healing_Potentia.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/101008816/ajptsp.2011.119.123-libre.pdf?1681297675=\u0026response-content-disposition=attachment%3B+filename%3DAntimicrobial_and_Wound_Healing_Potentia.pdf\u0026Expires=1732781320\u0026Signature=R89LByu9jg6DpN5GtmmF5cuBnR2YZEHXc2Tu2Opi1HJovNuIvZFrRQ6dBLp23ZdOjNMztRoAxg7JMqMfeAYYx3KtWhz42jcR7f4fVg-Z0c4DUFRRd4MnuPcZJ5yTdAwDRzK7NSVEUUP1vnELAu3qRyoemA64Q83FFLMyskqos6qFJq6fDvv5l7j1QAIeYmB81~SHRnD8hBMu~9sp6WflWsQLGHE6m1OO~Z-L7DMI5-Xquuf5kLDTXLOaPTSdDTaBSpBbu32SyQ9h~N09SiW4WtWV0889UwiksbsvTAVQrDQR~z3-7pzxy2qp3LBlwDkj0jEr0mSGBnNai2VYt3opFQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":220036,"name":"Antimicrobial","url":"https://www.academia.edu/Documents/in/Antimicrobial"},{"id":772284,"name":"Agar","url":"https://www.academia.edu/Documents/in/Agar"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96990401"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96990401/Protective_Effect_of_Annona_muricata_Linn_Fruit_Pulp_Lyophilized_Powder_against_Paracetamol_Induced_Redox_Imbalance_and_Hepatotoxicity_in_Rats"><img alt="Research paper thumbnail of Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats" class="work-thumbnail" src="https://attachments.academia-assets.com/98735858/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96990401/Protective_Effect_of_Annona_muricata_Linn_Fruit_Pulp_Lyophilized_Powder_against_Paracetamol_Induced_Redox_Imbalance_and_Hepatotoxicity_in_Rats">Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats</a></div><div class="wp-workCard_item"><span>Processes</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated f...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen (APAP). Male Sprague Dawley rats were orally pre-treated for 15 days with A. muricata lyophilized fruit pulp powder at low (1 g/kg b.wt) and high doses (2 g/kg b.wt). Silymarin (100 mg/kg) was administered as the standard drug. Hepatotoxicity was induced using APAP, in a single oral administration of 2.5 g/kg body weight dosage on the 15th day. Aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) were elevated in the APAP group but were found to be significantly reduced in the pre-treated groups in a dose-dependent manner. APAP administration brought down the serum total protein and albumin levels significantly. The activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase were reduced in the APAP administration; further, the reduced glutathione pool in ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ce5ad42e7291f2bd9f85b7f452dfa1a0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:98735858,&quot;asset_id&quot;:96990401,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/98735858/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96990401"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96990401"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96990401; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96990401]").text(description); $(".js-view-count[data-work-id=96990401]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96990401; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96990401']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96990401, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ce5ad42e7291f2bd9f85b7f452dfa1a0" } } $('.js-work-strip[data-work-id=96990401]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96990401,"title":"Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats","translated_title":"","metadata":{"abstract":"In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen (APAP). Male Sprague Dawley rats were orally pre-treated for 15 days with A. muricata lyophilized fruit pulp powder at low (1 g/kg b.wt) and high doses (2 g/kg b.wt). Silymarin (100 mg/kg) was administered as the standard drug. Hepatotoxicity was induced using APAP, in a single oral administration of 2.5 g/kg body weight dosage on the 15th day. Aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) were elevated in the APAP group but were found to be significantly reduced in the pre-treated groups in a dose-dependent manner. APAP administration brought down the serum total protein and albumin levels significantly. The activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase were reduced in the APAP administration; further, the reduced glutathione pool in ...","publisher":"MDPI AG","publication_name":"Processes"},"translated_abstract":"In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen (APAP). Male Sprague Dawley rats were orally pre-treated for 15 days with A. muricata lyophilized fruit pulp powder at low (1 g/kg b.wt) and high doses (2 g/kg b.wt). Silymarin (100 mg/kg) was administered as the standard drug. Hepatotoxicity was induced using APAP, in a single oral administration of 2.5 g/kg body weight dosage on the 15th day. Aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) were elevated in the APAP group but were found to be significantly reduced in the pre-treated groups in a dose-dependent manner. APAP administration brought down the serum total protein and albumin levels significantly. The activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase were reduced in the APAP administration; further, the reduced glutathione pool in ...","internal_url":"https://www.academia.edu/96990401/Protective_Effect_of_Annona_muricata_Linn_Fruit_Pulp_Lyophilized_Powder_against_Paracetamol_Induced_Redox_Imbalance_and_Hepatotoxicity_in_Rats","translated_internal_url":"","created_at":"2023-02-16T00:33:08.027-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98735858,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98735858/thumbnails/1.jpg","file_name":"pdf.pdf","download_url":"https://www.academia.edu/attachments/98735858/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Protective_Effect_of_Annona_muricata_Lin.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98735858/pdf-libre.pdf?1676537791=\u0026response-content-disposition=attachment%3B+filename%3DProtective_Effect_of_Annona_muricata_Lin.pdf\u0026Expires=1732781320\u0026Signature=Inol7qeV7~yMw9gcPgFpPuzKukE8q5Dtu42Rk9dsgGwDLg06nYzxZHt5eByIyhl9QWhNE~hc9jz-ZpCV6VnICdxv8Tjf80yMFPX0hFBPfoVWdGPkxAYm0Sd2LS6RPzmm5Y~9mQ7FRvDAh4bINZ2~B~sY796736gwyaVVbcZhPkUWhFd3FDupGtxs8jxFQlJlHnReQi8ZLQxGVMbsJXOiT0nFwwVyY-SctqmavXKUHkxXhd~enwU2UeYuZhcvGQIv1VbC7co1Cvjdvy0dYaiizNHfCxpEpYo81vs-gwRPvjBahUSqCy5R6-E6b6GIe6PsMxU4R7JJIXaqvyEJy8VBmg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Protective_Effect_of_Annona_muricata_Linn_Fruit_Pulp_Lyophilized_Powder_against_Paracetamol_Induced_Redox_Imbalance_and_Hepatotoxicity_in_Rats","translated_slug":"","page_count":13,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[{"id":98735858,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98735858/thumbnails/1.jpg","file_name":"pdf.pdf","download_url":"https://www.academia.edu/attachments/98735858/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Protective_Effect_of_Annona_muricata_Lin.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98735858/pdf-libre.pdf?1676537791=\u0026response-content-disposition=attachment%3B+filename%3DProtective_Effect_of_Annona_muricata_Lin.pdf\u0026Expires=1732781320\u0026Signature=Inol7qeV7~yMw9gcPgFpPuzKukE8q5Dtu42Rk9dsgGwDLg06nYzxZHt5eByIyhl9QWhNE~hc9jz-ZpCV6VnICdxv8Tjf80yMFPX0hFBPfoVWdGPkxAYm0Sd2LS6RPzmm5Y~9mQ7FRvDAh4bINZ2~B~sY796736gwyaVVbcZhPkUWhFd3FDupGtxs8jxFQlJlHnReQi8ZLQxGVMbsJXOiT0nFwwVyY-SctqmavXKUHkxXhd~enwU2UeYuZhcvGQIv1VbC7co1Cvjdvy0dYaiizNHfCxpEpYo81vs-gwRPvjBahUSqCy5R6-E6b6GIe6PsMxU4R7JJIXaqvyEJy8VBmg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":146183,"name":"Processes","url":"https://www.academia.edu/Documents/in/Processes"}],"urls":[{"id":29023251,"url":"https://www.mdpi.com/2227-9717/11/1/276/pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96990400"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96990400/O_%C3%B3leo_de_alho_Allium_sativum_L_Amaryllidaceae_como_potencial_protetor_contra_Anisakis_spp_Infec%C3%A7%C3%A3o_tipo_II_L3_Nematoda_em_ratos_Wistar"><img alt="Research paper thumbnail of O óleo de alho, Allium sativum L. (Amaryllidaceae), como potencial protetor contra Anisakis spp. Infecção tipo II (L3) (Nematoda) em ratos Wistar" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96990400/O_%C3%B3leo_de_alho_Allium_sativum_L_Amaryllidaceae_como_potencial_protetor_contra_Anisakis_spp_Infec%C3%A7%C3%A3o_tipo_II_L3_Nematoda_em_ratos_Wistar">O óleo de alho, Allium sativum L. (Amaryllidaceae), como potencial protetor contra Anisakis spp. Infecção tipo II (L3) (Nematoda) em ratos Wistar</a></div><div class="wp-workCard_item"><span>Revista Brasileira De Parasitologia Veterinaria</span><span>, 2021</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96990400"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96990400"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96990400; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96990400]").text(description); $(".js-view-count[data-work-id=96990400]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96990400; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96990400']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96990400, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=96990400]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96990400,"title":"O óleo de alho, Allium sativum L. (Amaryllidaceae), como potencial protetor contra Anisakis spp. Infecção tipo II (L3) (Nematoda) em ratos Wistar","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"Revista Brasileira De Parasitologia Veterinaria"},"translated_abstract":null,"internal_url":"https://www.academia.edu/96990400/O_%C3%B3leo_de_alho_Allium_sativum_L_Amaryllidaceae_como_potencial_protetor_contra_Anisakis_spp_Infec%C3%A7%C3%A3o_tipo_II_L3_Nematoda_em_ratos_Wistar","translated_internal_url":"","created_at":"2023-02-16T00:33:07.906-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"O_óleo_de_alho_Allium_sativum_L_Amaryllidaceae_como_potencial_protetor_contra_Anisakis_spp_Infecção_tipo_II_L3_Nematoda_em_ratos_Wistar","translated_slug":"","page_count":null,"language":"pt","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[],"research_interests":[{"id":148,"name":"Botany","url":"https://www.academia.edu/Documents/in/Botany"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":1111009,"name":"Allium Sativum","url":"https://www.academia.edu/Documents/in/Allium_Sativum"},{"id":1320129,"name":"Amaryllidaceae","url":"https://www.academia.edu/Documents/in/Amaryllidaceae"},{"id":3958878,"name":"Bulb","url":"https://www.academia.edu/Documents/in/Bulb"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96990387"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96990387/Chemical_Composition_and_Biological_Activities_of_the_Leaf_Essential_Oils_of_Curcuma_longa_Curcuma_aromatica_and_Curcuma_angustifolia"><img alt="Research paper thumbnail of Chemical Composition and Biological Activities of the Leaf Essential Oils of Curcuma longa, Curcuma aromatica and Curcuma angustifolia" class="work-thumbnail" src="https://attachments.academia-assets.com/98735848/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96990387/Chemical_Composition_and_Biological_Activities_of_the_Leaf_Essential_Oils_of_Curcuma_longa_Curcuma_aromatica_and_Curcuma_angustifolia">Chemical Composition and Biological Activities of the Leaf Essential Oils of Curcuma longa, Curcuma aromatica and Curcuma angustifolia</a></div><div class="wp-workCard_item"><span>Antibiotics</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Curcuma species are widely used as a food additive and also in various medicinal purposes. The pl...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Curcuma species are widely used as a food additive and also in various medicinal purposes. The plant is a rich source of essential oil and is predominantly extracted from the rhizomes. On the other hand, the leaves of the plants are usually considered as an agrowaste. The valorization of these Curcuma leaf wastes into essential oils is becoming accepted globally. In the present study, we aim to extract essential oils from the leaves of Curcuma longa (LEO), C. aromatica (REO), and C. anguistifolia (NEO). The chemical composition of these essential oils was analyzed by GC-MS. Free radical scavenging properties were evaluated against the radical sources, including DPPH, ABTS, and hydrogen peroxide. The antibacterial activity was assessed by the disc diffusion method and Minimum inhibitory concentration analysis against Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica) bacteria. Results identified the compounds α-p...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="113f9726981abf055619a5dd5a469aaa" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:98735848,&quot;asset_id&quot;:96990387,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/98735848/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96990387"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96990387"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96990387; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96990387]").text(description); $(".js-view-count[data-work-id=96990387]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96990387; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96990387']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96990387, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "113f9726981abf055619a5dd5a469aaa" } } $('.js-work-strip[data-work-id=96990387]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96990387,"title":"Chemical Composition and Biological Activities of the Leaf Essential Oils of Curcuma longa, Curcuma aromatica and Curcuma angustifolia","translated_title":"","metadata":{"abstract":"Curcuma species are widely used as a food additive and also in various medicinal purposes. The plant is a rich source of essential oil and is predominantly extracted from the rhizomes. On the other hand, the leaves of the plants are usually considered as an agrowaste. The valorization of these Curcuma leaf wastes into essential oils is becoming accepted globally. In the present study, we aim to extract essential oils from the leaves of Curcuma longa (LEO), C. aromatica (REO), and C. anguistifolia (NEO). The chemical composition of these essential oils was analyzed by GC-MS. Free radical scavenging properties were evaluated against the radical sources, including DPPH, ABTS, and hydrogen peroxide. The antibacterial activity was assessed by the disc diffusion method and Minimum inhibitory concentration analysis against Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica) bacteria. Results identified the compounds α-p...","publisher":"MDPI AG","publication_name":"Antibiotics"},"translated_abstract":"Curcuma species are widely used as a food additive and also in various medicinal purposes. The plant is a rich source of essential oil and is predominantly extracted from the rhizomes. On the other hand, the leaves of the plants are usually considered as an agrowaste. The valorization of these Curcuma leaf wastes into essential oils is becoming accepted globally. In the present study, we aim to extract essential oils from the leaves of Curcuma longa (LEO), C. aromatica (REO), and C. anguistifolia (NEO). The chemical composition of these essential oils was analyzed by GC-MS. Free radical scavenging properties were evaluated against the radical sources, including DPPH, ABTS, and hydrogen peroxide. The antibacterial activity was assessed by the disc diffusion method and Minimum inhibitory concentration analysis against Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica) bacteria. 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activity","url":"https://www.academia.edu/Documents/in/Antibacterial_activity"},{"id":382472,"name":"DPPH","url":"https://www.academia.edu/Documents/in/DPPH"},{"id":731133,"name":"Curcuma","url":"https://www.academia.edu/Documents/in/Curcuma"},{"id":765952,"name":"ABTS","url":"https://www.academia.edu/Documents/in/ABTS"},{"id":1120916,"name":"Camphor","url":"https://www.academia.edu/Documents/in/Camphor"},{"id":2280378,"name":"Eucalyptol","url":"https://www.academia.edu/Documents/in/Eucalyptol"}],"urls":[{"id":29023243,"url":"https://www.mdpi.com/2079-6382/11/11/1547/pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="88102755"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/88102755/Therapeutic_properties_and_molecular_docking_study_of_some_phenolic_compounds_as_anti_human_lung_cancer_potential_A_biochemical_approach"><img alt="Research paper thumbnail of Therapeutic properties and molecular docking study of some phenolic compounds as anti‐human lung cancer potential: A biochemical approach" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/88102755/Therapeutic_properties_and_molecular_docking_study_of_some_phenolic_compounds_as_anti_human_lung_cancer_potential_A_biochemical_approach">Therapeutic properties and molecular docking study of some phenolic compounds as anti‐human lung cancer potential: A biochemical approach</a></div><div class="wp-workCard_item"><span>Journal of Biochemical and Molecular Toxicology</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="88102755"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="88102755"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 88102755; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=88102755]").text(description); $(".js-view-count[data-work-id=88102755]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 88102755; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='88102755']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 88102755, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=88102755]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":88102755,"title":"Therapeutic properties and molecular docking study of some phenolic compounds as anti‐human lung cancer potential: A biochemical approach","translated_title":"","metadata":{"publisher":"Wiley","publication_name":"Journal of Biochemical and Molecular Toxicology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/88102755/Therapeutic_properties_and_molecular_docking_study_of_some_phenolic_compounds_as_anti_human_lung_cancer_potential_A_biochemical_approach","translated_internal_url":"","created_at":"2022-10-08T01:00:18.925-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":67234001,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Therapeutic_properties_and_molecular_docking_study_of_some_phenolic_compounds_as_anti_human_lung_cancer_potential_A_biochemical_approach","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":67234001,"first_name":"Hamida","middle_initials":"","last_name":"Hamdi","page_name":"HamidaHamdi","domain_name":"independent","created_at":"2017-08-13T09:17:16.158-07:00","display_name":"Hamida Hamdi","url":"https://independent.academia.edu/HamidaHamdi"},"attachments":[],"research_interests":[{"id":834031,"name":"Biochemical and Molecular Toxicology","url":"https://www.academia.edu/Documents/in/Biochemical_and_Molecular_Toxicology"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[{"id":24575728,"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbt.23222"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="88102754"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/88102754/Chemical_Composition_and_Antioxidant_Antiviral_Antifungal_Antibacterial_and_Anticancer_Potentials_of_Opuntia_ficus_indica_Seed_Oil"><img alt="Research paper thumbnail of Chemical Composition and Antioxidant, Antiviral, Antifungal, Antibacterial and Anticancer Potentials of Opuntia ficus-indica Seed Oil" class="work-thumbnail" src="https://attachments.academia-assets.com/92144576/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/88102754/Chemical_Composition_and_Antioxidant_Antiviral_Antifungal_Antibacterial_and_Anticancer_Potentials_of_Opuntia_ficus_indica_Seed_Oil">Chemical Composition and Antioxidant, Antiviral, Antifungal, Antibacterial and Anticancer Potentials of Opuntia ficus-indica Seed Oil</a></div><div class="wp-workCard_item"><span>Molecules</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Opuntia ficus-indica (OFI) is a cactus that is widely cultivated in the Kingdom of Saudi Arabia e...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Opuntia ficus-indica (OFI) is a cactus that is widely cultivated in the Kingdom of Saudi Arabia especially in the Taif region due to its favorable weather for growing, and it has benefits as a food and traditional medicine. The aim of the current study was to chemically characterize Opuntia ficus-indica seed oil from Taif, Kingdom of Saudi Arabia, using GC-MS and HPLC analysis and evaluate its antioxidant, antiviral, antifungal, antibacterial and anticancer activities. Linolenic acid was the dominating fatty acid in OFI oil, followed by oleic acid, linoleic acid, palmitic acid and stearic acid. Total tocopherol (α-, β-, Ɣ-tocopherol) was found to be 24.02 μg/mL. Campesterol was the main phytosterol, followed by γ- &amp; β -sitosterol, and Stigmasterol. The phenolic components scored 30.5 mg gallic acid equivalent per ml of oil with 89.2% antioxidant activity (% DPPH radical inhibition) at 200 µL/mL of OFI oil. OFI oil showed an inhibition efficacy against microbial strains especially Sa...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="81710b04d5f681def173857659f07077" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:92144576,&quot;asset_id&quot;:88102754,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/92144576/download_file?st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&st=MTczMjc3NzcyMSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="88102754"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="88102754"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 88102754; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=88102754]").text(description); $(".js-view-count[data-work-id=88102754]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 88102754; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='88102754']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 88102754, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "81710b04d5f681def173857659f07077" } } $('.js-work-strip[data-work-id=88102754]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":88102754,"title":"Chemical Composition and Antioxidant, Antiviral, Antifungal, Antibacterial and Anticancer Potentials of Opuntia ficus-indica Seed Oil","translated_title":"","metadata":{"abstract":"Opuntia ficus-indica (OFI) is a cactus that is widely cultivated in the Kingdom of Saudi Arabia especially in the Taif region due to its favorable weather for growing, and it has benefits as a food and traditional medicine. 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