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Antibody Synthesis | GENEWIZ from Azenta
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href='https://www.azenta.com/' style='color:#826ec3;font-size:17px'>Azenta Life Sciences – Services</a></li><br><li><a class='GColor' href='/en/Public/Services/Next-Generation-Sequencing' style='color:#826ec3;font-size:17px'>Next Generation Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/RNA-Seq' style='color:#585F69;font-size:14px'>RNA-Seq</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Proteomics' style='color:#585F69;font-size:14px'>Proteomics</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/High-Throughput-Gene-Expression-Screening' style='color:#585F69;font-size:14px'>High-Throughput Gene Expression Screening <sup style="color:#826ec3; font-weight: bold;">NEW</sup></a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Single-Cell-Sequencing' style='color:#585F69;font-size:14px'>Single-Cell Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Exome-Sequencing' style='color:#585F69;font-size:14px'>Exome Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Amplicon-Sequencing-Services' style='color:#585F69;font-size:14px'>Amplicon Sequencing Services</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Standalone-NGS-Solutions' style='color:#585F69;font-size:14px'>Sequencing Only<br></a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Whole-Genome-Sequencing' style='color:#585F69;font-size:14px'>Whole Genome Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/High-Throughput-Genotyping' style='color:#585F69;font-size:14px'>CRISPR Validation</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Targeted-Resequencing-Panels' style='color:#585F69;font-size:14px'>Targeted Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Metagenomics-Solutions' style='color:#585F69;font-size:14px'>Metagenomics </a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Epigenomics' style='color:#585F69;font-size:14px'>Epigenomics</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Antibody-Discovery' style='color:#585F69;font-size:14px'>Antibody Discovery <sup style="color:#826ec3; font-weight: bold;">NEW</sup></a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Immunogenomics' style='color:#585F69;font-size:14px'>Immunogenomics</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Digital-Spatial-Profiling' style='color:#585F69;font-size:14px'>Digital Spatial Profiling</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/AAV-Genome-Sequencing' style='color:#585F69;font-size:14px'>AAV Genome Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Whole-Plasmid-Sequencing-Plasmid-EZ' style='color:#585F69;font-size:14px'>Whole Plasmid Sequencing: Plasmid-EZ <sup style="color:#826ec3; font-weight: bold;">NEW</sup></a></li></ul></div><div class='col-md-3 '><ul class='list-unstyled'><li><a class='GColor' href='/en/Public/Services/Sanger-Sequencing' style='color:#826ec3;font-size:17px'>Sanger Sequencing</a></li><li><a href='/en/Public/Services/Sanger-Sequencing/Sanger-EZ' style='color:#585F69;font-size:14px'>Sanger-EZ <sup style="color:#826ec3; font-weight: bold;">NEW</sup></a></li><li><a href='/en/Public/Services/Sanger-Sequencing/AAV-ITR' style='color:#585F69;font-size:14px'>AAV-ITR Sanger Sequencing</a></li><li><a href='/en/Public/Services/Sanger-Sequencing/Purified-Templates' style='color:#585F69;font-size:14px'>Purified Templates</a></li><li><a href='/en/Public/Services/Sanger-Sequencing/Difficult-Template-Sequencing' style='color:#585F69;font-size:14px'>Difficult Template Sequencing</a></li><li><a href='/en/Public/Services/Sanger-Sequencing/Direct-Colony-Sequencing' style='color:#585F69;font-size:14px'>Direct Colony Sequencing</a></li><li><a href='/en/Public/Services/Sanger-Sequencing/PCR-Purification' style='color:#585F69;font-size:14px'>PCR Purification</a></li><li><a href='/en/Public/Services/Sanger-Sequencing/Primer-Walking' style='color:#585F69;font-size:14px'>Primer Walking</a></li><br><li><a class='GColor' href='/en/Public/Services/Molecular-Genetics' style='color:#826ec3;font-size:17px'>PCR + Sanger Services</a></li><li><a href='/en/Public/Services/Molecular-Genetics/Bacterial-and-Fungal-Identification' style='color:#585F69;font-size:14px'>Bacterial and Fungal Identification</a></li><li><a href='/en/Public/Services/Molecular-Genetics/Mutation-Analysis' style='color:#585F69;font-size:14px'>Mutation Analysis</a></li><li><a href='/en/Public/Services/Molecular-Genetics/SNP-Genotyping' style='color:#585F69;font-size:14px'>SNP Genotyping</a></li><li><a href='/en/Public/Services/Molecular-Genetics/PCR-Plus-Sequencing-CRISPR-Analysis-Package' style='color:#585F69;font-size:14px'>PCR Plus Sequencing CRISPR Analysis Package</a></li><li><a href='/en/Public/Services/Molecular-Genetics/cDNA-Verification' style='color:#585F69;font-size:14px'>Confirmatory Sequencing & Cell Bank Characterization</a></li><li><a href='/en/Public/Services/Molecular-Genetics/Yeast-Colony-Sequencing' style='color:#585F69;font-size:14px'>Yeast Colony Sequencing</a></li><li><a href='/en/Public/Services/Molecular-Genetics/Fragment-Analysis' style='color:#585F69;font-size:14px'>Fragment Analysis</a></li><li><a href='/en/Public/Services/Molecular-Genetics/PCR-Solutions' style='color:#585F69;font-size:14px'>Quantitative PCR & Digital PCR <sup style="color:#826ec3;"><strong>NEW </strong></sup></a></li><li><a href='/en/Public/Services/Molecular-Genetics/Nucleic-Acid-Extraction' style='color:#585F69;font-size:14px'>Nucleic Acid Extraction</a></li></ul></div><div class='col-md-3 '><ul class='list-unstyled'><li><a class='GColor' href='/en/Public/Services/Gene-Synthesis' style='color:#826ec3;font-size:17px'>DNA & RNA Synthesis</a></li><li><a href='/en/Public/Services/Gene-Synthesis/Gene-Synthesis' style='color:#585F69;font-size:14px'>Gene Synthesis</a></li><li><a href='/en/Public/Services/Gene-Synthesis/Antibody-DNA-Synthesis' style='color:#585F69;font-size:14px'>Antibody Synthesis</a></li><li><a href='/en/Public/Services/Gene-Synthesis/AAV-Plasmid-Synthesis' style='color:#585F69;font-size:14px'>AAV Plasmid Synthesis</a></li><li><a href='/en/Public/Services/Gene-Synthesis/Gene-Fragments' style='color:#585F69;font-size:14px'>Gene Fragments</a></li><li><a href='/en/Public/Services/Gene-Synthesis/CRISPR-Construct-Synthesis' style='color:#585F69;font-size:14px'>CRISPR Construct Synthesis</a></li><li><a href='/en/Public/Services/Gene-Synthesis/Synthetic-DNA-Libraries' style='color:#585F69;font-size:14px'>Synthetic DNA Libraries</a></li><li><a href='/en/Public/Services/Gene-Synthesis/Single-Stranded-DNA-Synthesis' style='color:#585F69;font-size:14px'>ssDNA Synthesis</a></li><li><a href='/en/Public/Services/Gene-Synthesis/DNA-Cloning' style='color:#585F69;font-size:14px'>DNA Cloning</a></li><li><a href='/en/Public/Services/Gene-Synthesis/Site-Directed-Mutagenesis' style='color:#585F69;font-size:14px'>Site-Directed Mutagenesis<br></a></li><li><a href='/en/Public/Services/Gene-Synthesis/Viral-Package' style='color:#585F69;font-size:14px'>Viral Packaging <sup style="color:#826ec3;"><strong>NEW </strong></sup></a></li><li><a href='/en/Public/Services/Gene-Synthesis/Recombinant-Antibody-Production' style='color:#585F69;font-size:14px'>Recombinant Antibody Production <sup style="color:#826ec3;"><strong>NEW </strong></sup></a></li><li><a href='/en/Public/Services/Gene-Synthesis/Custom-mRNA-Synthesis' style='color:#585F69;font-size:14px'>Custom mRNA Synthesis <sup style="color:#826ec3; font-weight: bold;">NEW</sup></a></li><br><li><a class='GColor' href='/en/Public/Services/Oligo' style='color:#826ec3;font-size:17px'>Oligo Synthesis Services</a></li><li><a href='/en/Public/Services/Oligo/Overnight-DNA-Oligos' style='color:#585F69;font-size:14px'>Overnight DNA Oligos</a></li><li><a href='/en/Public/Services/Oligo/Custom-DNA-and-RNA-Oligos' style='color:#585F69;font-size:14px'>Custom DNA and RNA Oligos</a></li><li><a href='/en/Public/Services/Oligo/Oligo-Retained-for-Sanger-Sequencing' style='color:#585F69;font-size:14px'>Oligo Retained for Sanger Sequencing</a></li></ul></div><div class='col-md-3 '><ul class='list-unstyled'><li><a class='GColor' href='/en/Public/Services/Plasmid-DNA-Prep' style='color:#826ec3;font-size:17px'>Plasmid DNA Preparation</a></li><li><a href='/en/Public/Services/Plasmid-DNA-Prep/Standard' style='color:#585F69;font-size:14px'>Standard Plasmid DNA Prep</a></li><li><a href='/en/Public/Services/Plasmid-DNA-Prep/Targeted-Yield' style='color:#585F69;font-size:14px'>Targeted Yield Plasmid DNA Prep</a></li><li><a href='/en/Public/Services/Plasmid-DNA-Prep/AAV-Plasmid-Preparation' style='color:#585F69;font-size:14px'>AAV Plasmid Preparation</a></li><br><li><a class='GColor' href='/en/Public/Services/Clinical-Services' style='color:#826ec3;font-size:17px'>PreClinical and Clinical Services</a></li><li><a href='/en/Public/Services/Clinical-Services/Clinical-Services-Overview' style='color:#585F69;font-size:14px'>Clinical Services</a></li><li><a href='/en/Public/Services/Clinical-Services/Microarray-Solutions' style='color:#585F69;font-size:14px'>Microarray Solutions <sup style="color:#826ec3; font-weight: bold;">NEW</sup></a></li><li><a href='/en/Public/Services/Clinical-Services/CLIA-Variant-Confirmation' style='color:#585F69;font-size:14px'>CLIA Variant Confirmation (PCR + Sanger)</a></li><li><a href='/en/Public/Services/Clinical-Services/CLIA-Sanger-Sequencing' style='color:#585F69;font-size:14px'>CLIA Sanger Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/CLIA-Whole-Exome-Sequencing' style='color:#585F69;font-size:14px'>CLIA Whole Exome Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/CLIA-Whole-Genome-Sequencing' style='color:#585F69;font-size:14px'>CLIA Whole Genome Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/Regulatory' style='color:#585F69;font-size:14px'>GLP-Compliant Overview</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-Confirmatory-Sequencing' style='color:#585F69;font-size:14px'>GLP Confirmatory Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-SNP-Mutation-Analysis' style='color:#585F69;font-size:14px'>GLP SNP Mutation Analysis</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-Plasmid-Prep' style='color:#585F69;font-size:14px'>GLP Plasmid Prep</a></li><li><a href='/en/Public/Services/Clinical-Services/Nucleic-Acid-Extraction' style='color:#585F69;font-size:14px'>GLP Nucleic Acid Extraction</a></li><li><a href='/en/Public/Services/Clinical-Services/Biofluid-Processing-Overview' style='color:#585F69;font-size:14px'>Biofluid Processing</a></li><li><a href='/en/Public/Services/Clinical-Services/CLIA-Integration-Site-Analysis' style='color:#585F69;font-size:14px'>CLIA Integration Site Analysis <sup style="color:#826ec3; font-weight: bold;">NEW</sup></a></li></ul></div></div></div></li></ul></li><li class='dropdown'><a href='/en/Public/Research-Areas' data-toggle='dropdown' class='dropdown-toggle' style='color:white;height:52px;top:47px;padding-top:0;background-color:transparent;font-size:17px;font-weight:bold;'>RESEARCH AREAS</a><ul class='dropdown-menu'><li class='dropdown'><a class='GColor' href='/en/Public/Research-Areas/AAV' style='font-size:17px'>AAV Services</a><ul class='dropdown-menu'></ul></li><li class='dropdown'><a class='GColor' href='/en/Public/Research-Areas/Agriculture-Food-Science' style='font-size:17px'>Agriculture and Food Science</a><ul class='dropdown-menu'></ul></li><li class='dropdown'><a class='GColor' 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padding: 0; } .intro-new-container { background: #f0f0f0; padding: 30px 0; } .intro-new-container h1 { margin: 0; color: #000000; } .intro-new-content p { color: #000000; } .intro-new-content { width: 1170px; margin: 0 auto; } .intro-content-box { display: inline-block; vertical-align: middle; /*width: 50%;*/ } #intro-content-box-left { width: 60%; text-align: left; padding: 30px 0; } #intro-content-box-right { width: 39%; text-align: right; } .intro-content-box img { width: 400px; } .intro-content-box button { border: none; border-radius: 4px; background: #826ec3; padding: 10px 20px; color: #fff; font-size: 15px; letter-spacing: 1px; } .intro-content-box button:hover { background: #6965a1; } @media only screen and (max-width: 768px) { .headline-center { padding-top: 0; } .intro-new-container { text-align: center; margin-top: 0; } .intro-new-content { width: 90%; margin: 0 auto; } .intro-new-content { display: inline-block; } #intro-content-box-right, #intro-content-box-left { width: 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This is the fastest turnaround time on the market. Our high-quality results are paired with FREE recombinant antibody expression optimization and FREE cloning vector storage for up to 2 years.</p> <p>GENEWIZ Multiomics and Synthesis Solutions from Azenta Life Sciences offers a customer-friendly antibody synthesis service with Ph.D.-level technical support to alleviate common synthesis obstacles and streamline your antibody discovery research.</p> <p> </p> <a href="https://web.genewiz.com/gene-synth-inquiry?utm_source=antibody-synthesis" target="_blank"><button>Request Quote</button></a> </div> <div class="intro-content-box" id="intro-content-box-right"> <a rel="noopener noreferrer" href="https://www.genewiz.com/en/Public/Services/Gene-Synthesis/Recombinant-Antibody-Production" target="_blank"><img alt="" src="/-/media/Images/Gene-to-Antibody_US_Web-Ban_Right.ashx?la=en&hash=2FF03A93A8F5216C101ED1D6E3876B34CF87341C"></a> </div> </div> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .body { text-align: center; display: inline-block; } .banner2 { width: 1170px; background-image: url('/-/media/12021-D_Competent-Cells_WebBanFull-Lrg_Background.ashx'); background-size: cover; text-align: center; display: flex; padding: 10px; } .banner2 img { text-align: center; display: block; margin-left: auto; margin-right: auto; } #banner2-left { width: 30%; padding: 25px; padding-left: 50px; } #banner2-right { width: 65%; padding: 25px; padding-left: 25px; } #banner2-right h2 { text-transform: none; letter-spacing: 1px; line-height: 50px; border-bottom: none; font-family: 'Roboto', sans-serif; font-weight: 400; font-size: 45px; margin: 0; margin-top: 15px; margin-bottom: 5px; color: #ffffff; } #banner2-right h3 { text-transform: none; letter-spacing: 1px; line-height: 30px; border-bottom: none; font-family: 'Roboto', sans-serif; font-weight: 400; font-size: 25px; margin: 0; margin-bottom: 20px; color: #ffffff; } #banner2-right p { text-transform: none; letter-spacing: 1px; line-height: 20px; border-bottom: none; font-family: 'Roboto', sans-serif; font-weight: 400; font-size: 15px; margin: 0; margin-top: 20px; color: #ffffff; } #banner2-right button { padding: 8px 19px; color: #826ec3; letter-spacing: 1px; background: #ffffff; border: 2px solid #ffffff; border-radius: 0px; transition: all .2s ease-in-out; font-size: 15px; font-weight: bold; } #banner2-right button:hover { cursor: pointer; transform: scale(1.1); } #banner2-right button:focus { outline: 0; } @media only screen and (max-width: 1170px) { .banner2 { width: 95%; height: auto; background-image: url('/-/media/12021-D_Competent-Cells_WebBanFull-Lrg_Background.ashx'); display: inline-block; } #banner2-left { text-align: center; width: 100%; } #banner2-right { text-align: center; width: 100%; } #banner2-right h2 { text-transform: none; letter-spacing: 1px; line-height: 50px; border-bottom: none; font-family: 'Roboto', sans-serif; font-weight: 400; font-size: 45px; margin: 0; margin-bottom: 15px; color: #ffffff; } #banner2-right h3 { text-transform: none; letter-spacing: 1px; line-height: 20px; border-bottom: none; font-family: 'Roboto', sans-serif; font-weight: 400; font-size: 20px; margin: 0; margin-bottom: 15px; color: #ffffff; } #banner2-left img { width: auto; height: auto; } #banner2-right img { width: 90%; height: auto; } @media only screen and (max-width: 700px) { #banner2-left img { width: 60%; } #banner2-right button { font-size: 14px; } } </style> <div class="body"> <div class="banner2"> <div id="banner2-left"> <img alt="" src="/-/media/12021-D_Competent-Cells_WebBanFull-Lrg_Thumbnail.ashx?la=en&hash=03D06DF38C68AA688D331E471D55F4F288AB7840" /> </div> <div id="banner2-right"> <h2>Competent Cells<br /> Selection Guide</h2> <h3>Learn how to identify the most suitable <em>E.coli</em> strain<br /> and protocol for competent cells</h3> <a rel="noopener noreferrer" rel="noopener noreferrer" href="https://hubs.ly/Q02YbDT70" target="_blank"><button>DOWNLOAD</button></a> </div> </div> </div> <p> </p> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .question { width: 1170px; display: inline-block; } .question p { width: 90%; text-align: left; } .question ul { width: 90%; text-align: left; } @media screen and (max-width: 1170px) { .question { width: auto; } } </style> <div class="question"> <h2>What is the process of Antibody Synthesis?</h2> <p>Antibody synthesis is the production of antibodies – proteins created by the immune system of a host — in response to an antigen, a foreign body that enters the host. The production of an antibody involves several steps:</p> <ul> <li>Preparation of the immunogen</li> <li>Immunization</li> <li>Creation of a hybridoma</li> <li>Collection</li> <li>Screening</li> <li>Isotyping</li> <li>Purification of the antibody</li> <li>Antibody labeling for direct use</li> </ul> </div> </div> <script type="text/javascript" src="/assets/plugins/counter/jquery.counterup.min.js"></script> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".row .category").find("img").addClass("img-responsive"); }); </script> <div class='Component-Frame pull-center Multi-column-TextBullet-Layout Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="container"> <div class="headline-center"> <h2>Antibody Synthesis Features & Benefits</h2> </div> <div class="headline-left"> </div> <div class="row category"> <div class="col-md-6 col-sm-6"> <div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> <strong>Rapid Turnaround Time</strong> – Starting at just 6 days to meet your project deadlines </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> <strong>Quality Control</strong> – Stringent quality control with guaranteed 100% sequence accuracy </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> <strong>Vector Storage</strong> – FREE cloning vector storage for up to 2 years </div> </div> </div> <div class="col-md-6 col-sm-6"> <div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> <strong>Codon Optimization</strong> – Optimize recombinant antibody expression using our FREE <a href="https://clims4.genewiz.com/RegisterAccount/Login?returnUrl=https://clims4.local.genewiz.com/Toolbox/CodonOptimization" target="_blank">codon optimization tool</a> </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> <strong>Large-Scale Plasmid Prep</strong> – Multiple plasmid DNA preparation options from ug to mg </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> <strong>Ph.D.-Level Customer Support</strong> – Our dedicated Project Management team provides consultation and support for your project, from start to finish </div> </div> </div> </div> </div> </div><div class="headline-center Rich-Text-Edit-Area"> <div class="container"> <h2>FASTEST ANTIBODY DNA SYNTHESIS ON THE MARKET</h2> <div class="row"> <div class="col-md-9 col-centered"> <table class="table table-responsive table-bordered"> <tbody class="panel panel-purple"> <tr class="panel-heading"> <td>Synthetic Gene Length</td> <td>Turnaround Time (TAT)</td> </tr> <tr> <td><500 bp</td> <td style="background-color: #ffed83;" rowspan="2"><strong><br /> 6-8 Business Days</strong></td> </tr> <tr> <td>501-750 bp</td> </tr> <tr> <td>751-1500 bp</td> <td style="background-color: #ffed83;"><strong>8-10 Business Days</strong></td> </tr> <tr> <td>Custom cloning</td> <td style="background-color: #ffed83;"><strong>No Additional TAT</strong></td> </tr> </tbody> </table> </div> </div> </div> <br /> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .research { width: 1170px; display: inline-block; text-align: center; padding-top: 20px; padding-bottom: 20px; } .research img { max-width: 900px; width: 100%; height: auto; display: block; margin-left: auto; margin-right: auto; } @media screen and (max-width: 1170px) { .research { width: auto; } .research img { width: 95%; height: auto; } } </style> <div class="research"> <h2 style="text-align: center;"> Synthesize all types of DNA Sequences for Antibody Research</h2> <p>Advancements in recombinant monoclonal antibody (rAb) technology have led to the development of a variety of engineered antibody molecules for research, diagnosis, and therapy. With over 10 years of expertise in <a href="https://www.genewiz.com/en/Public/Services/Gene-Synthesis">gene synthesis</a> and cloning, Azenta has supported numerous antibody discovery and development projects, including researchers developing broadly anti-virus monoclonal antibodies <sup>[1]</sup>, bispecific recombinant antibodies <sup>[2]</sup>, anticancer Fc-engineered human monoclonal antibody <sup>[3, 4]</sup>, and much more. </p> <img alt="" src="/-/media/Images/2xGSAntibodyDNASynthesisSequencesforAntibodyResearch2x1.ashx?la=en&hash=FAABF1CCCCF3B9C446FC00BA50481378DF5F557F"> <br> <h3>Figure 1. Synthetic DNA in antibody development</h3> <p>Recombinant antibodies can be developed using de novo synthesis of recombinant VDJ light chain and heavy chain sequences. Synthetic DNA can be also used in humanized or other recombinant antibodies such as single-chain variable fragment (scFv), single domain antibody (sdAb), fragment antigen binding mAb (Fab), trifunctional antibody, etc.</p> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .research { width: 1170px; display: inline-block; text-align: center; padding-top: 20px; padding-bottom: 20px; } .research img { max-width: 1100px; height: auto; display: block; margin-left: auto; margin-right: auto; } @media screen and (max-width: 1170px) { .research { width: auto; } } </style> <div class="research"> <h2 style="text-align: center;"> </h2> <img alt="" src="/-/media/Images/2xRecombinantAntibodyProductionWorkflow2x1.ashx?la=en&hash=F0FEE879F4872532B29CFDDD1D17EB04F6A995DC" /> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <div class="development"> <h2>WHAT OUR CUSTOMERS ARE SAYING</h2> <p><em>“I have always had great customer service from Azenta, received great products with a good price. It allows me to do other things in the lab instead of spending time cloning, etc.”<br> -<span> </span><strong>Researcher from Cincinnati Children's Hospital Medical Center</strong></em></p> <p><em><br> “Good quality, customer support, and expediated delivery to help me to meet the deadline.”<br> -<span> </span><strong>Principal Investigator from a top pharmaceutical company</strong></em></p> </div> </div> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Gray margin-top-0 margin-bottom-0 padding-top-10 padding-bottom-0 "> <div class=" container"> <div class="headline-center"> <h2>Technical Resources</h2> <p></p> </div> <ul class="list-unstyled row "> <li class='col-sm-6'> <a href='/Public/Resources/FAQs/FAQs-Gene-Synthesis' target='blank'> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/chat-bubble_Purple.ashx?h=110&la=en&w=210&hash=20D4E093CF40A1D72E7CE3721F0FDEAC239B298C" alt="Building" width="210" height="110" /> </div> <div class="row"> <h3>Frequently Asked Questions</h3> </div> <div class="row"> </div> </div> </a> </li> <!--target="blank"--> <li class='col-sm-6'> <a href='https://clims4.genewiz.com/RegisterAccount/Login?returnUrl=https://clims4.genewiz.com//Toolbox/CodonOptimization' target='_blank'> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/Codon_Optimization_Web_Icon_Purple.ashx?h=110&la=en&w=210&hash=D7FFFDC88326FEA1C7F62AE4ED09EA2FCED27D70" alt="Building" width="210" height="110" /> </div> <div class="row"> <h3>Codon Optimization Tool</h3> </div> <div class="row"> </div> </div> </a> </li> <!--target="_blank"--> </ul> <div class="row headline-center"> </div> </div> </div><div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> body { margin: 0; } .tech-resources-container { width: 1170px; margin: 0 auto; padding: 20px; } .tech-resources-container h2 { text-align: center; border-bottom: none; } .tech-resource { display: flex; align-items: center; flex-direction: row; margin-bottom: 35px; } .resource { flex-grow: 1; } .resource-right h3, .resource-right p { width: 90%; margin: 0 auto; border-bottom: none; text-align: left; } .resource button { padding: 5px 15px; border: none; border-radius: 4px; background: #826ec3; color: #fff; font-size: 15px; font-weight: lighter; letter-spacing: 1px; margin-top: 15px; -webkit-transition: ease-in-out 0.2s; -moz-transition: ease-in-out 0.2s; -o-transition: ease-in-out 0.2s; transition: ease-in-out 0.2s; } .resource button:hover { background: #6959a1; } @media only screen and (max-width: 800px) { .tech-resource { flex-direction: column; text-align: center; } .resource-right h3, .resource-right p { text-align: center; } } @media only screen and (max-width: 1170px) { .tech-resources-container { width: 80%; margin: 0 auto; } } </style> <div style="width: 100%; background-color: #f0f0f0; padding: 20px; margin: 0;margin-top: -20px;"> <div class="tech-resources-container"> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/rAB-Application-Note-Thumbnail.ashx?la=en&hash=ABD1E9B71BDD69A5EFA233AA96DE8809A3166D86" /> </div> <div class="resource resource-right"> <h3>Application Note | Accelerating Recombinant Antibody Production</h3> <p>Recombinant antibody production is a cornerstone of modern biotechnology and research, but it faces the significant challenge of achieving high yields. In this application note, discover how to enhance expression efficiency while reducing production times with an optimized vector backbone workflow. <br /> <a href="https://hubs.ly/Q02PhGG80" target="_blank"> <button>Download Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Plasmid-Prep-Tech-Note-Thumbnail.ashx?la=en&hash=C5845AA7ECA3C368E4344A363ABED340B41DA741" /> </div> <div class="resource resource-right"> <h3>Tech Note | Optimizing Plasmid Preparation to Increase Yield and Reduce Endotoxins</h3> <p>Plasmid DNA (pDNA) is vital for a range of biopharmaceutical and biotechnological applications but maximizing yield while minimizing endotoxins can be challenging. This tech note explores strategies to optimize bacterial growth conditions, enhance lysis, and refine purification protocols to boost pDNA yield and purity, ensuring consistent, high-quality results. <br /> <a href="https://hubs.ly/Q02Y31xg0" target="_blank"> <button>Download Now</button> </a> </p> </div> </div> </div> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .publication { width: 1170px; display: inline-block; text-align: left; padding-top: 20px; padding-bottom: 20px; } @media screen and (max-width: 1170px) { .publication { width: auto; } } </style> <div class="publication"> <h2 style="text-align: center;">RELATED PUBLICATIONS</h2> <p><sup>[1]</sup>Xiao H, Guo T, Yang M, et al. Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses. Cell Discov. 2019;5:21. Published 2019 Apr 16. doi:10.1038/s41421-019-0086-x</p> <p><sup>[2]</sup>Ahmed M, Lopez-Albaitero A, Pankov D, et al. TCR-mimic bispecific antibodies targeting LMP2A show potent activity against EBV malignancies. JCI Insight. 2018;3(4):e97805. Published 2018 Feb 22. doi:10.1172/jci.insight.97805</p> <p><sup>[3]</sup> Qi X, Li F, Wu Y, et al. Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity. Nat Commun. 2019;10(1):2141. Published 2019 May 20. doi:10.1038/s41467-019-10088-1</p> <p><sup>[4]</sup>Dahan R, Barnhart BC, Li F, Yamniuk AP, Korman AJ, Ravetch JV. Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement. 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} #banner3-right button { font-size: 14px; } } </style> <div class="body"> <div class="banner3"> <div id="banner3-left"> <h3 style="text-align:left;">STREAMLINE YOUR PATH TO DISCOVERY</h3> <h2 style="text-align:left;">Gene-to-Discovery Solutions</h2> <h3 style="text-align:left;">AAV Packaging, Custom mRNA Synthesis, Lentivirus Packaging, Recombinant Antibody Production</h3> <br /> <a rel="noopener noreferrer" rel="noopener noreferrer" href="https://hubs.ly/Q02gBwzs0" target="_blank"><button style="text-align:left;">LEARN MORE</button></a> </div> </div> </div> </div> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10"> <div class="container"> <div class="headline-center"> <h2>Related Services</h2> <p></p> </div> <ul class="list-unstyled row "> <li class='col-sm-3'> <a href='https://www.genewiz.com/en/Public/Services/Next-Generation-Sequencing/Antibody-Discovery' target=''> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Antibody-Discovery-Module-Purple_210x110.ashx?h=110&la=en&w=210&hash=EE3BAF1E12AADF2FD428C0EFF880DA300903CCD5" alt="Building" width="210" height="110" title="Precision Antibody Icon Small" /> </div> <div class="row"> <h3>Antibody Discovery</h3> </div> <div class="row"> </div> </div> </a> </li> <!--target=""--> <li class='col-sm-3'> <a href='/en/Public/Services/Gene-Synthesis/Synthetic-DNA-Libraries' target=''> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/Synthetic_DNA_Libraries_Icon_Purple.ashx?h=110&la=en&w=210&hash=0AE168240345420DA1791122FE70DC0981367FA6" alt="Building" width="210" height="110" /> </div> <div class="row"> <h3>Synthetic DNA Libraries</h3> </div> <div class="row"> </div> </div> </a> </li> <!--target=""--> <li class='col-sm-3'> <a href='/en/Public/Services/Plasmid-DNA-Prep' target=''> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/plasmid-prep-overview_110x210_Purple.ashx?h=110&la=en&w=210&hash=D542B9BF1106F547CB84A8011F635AD43B95653A" alt="Building" width="210" height="110" /> </div> <div class="row"> <h3>Plasmid DNA Preparation</h3> </div> <div class="row"> </div> </div> </a> </li> <!--target=""--> <li class='col-sm-3'> <a href='/en/Public/Services/Gene-Synthesis/FragmentGENE' target=''> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/Fragment-Gene_Web-Icon-Service_Purple_DESIGN.ashx?h=111&la=en&w=211&hash=8B6C44621515B4D66E237B533867CEBF28597388" alt="Building" width="211" height="111" /> </div> <div class="row"> <h3>FragmentGENE</h3> </div> <div class="row"> </div> </div> </a> </li> <!--target=""--> </ul> <div class="row headline-center"> </div> </div> </div><!--=== Process v1 ===--> <div class="process-v1 How-To-Order Component-BackGround-Gray margin-top-0 padding-top-10 padding-bottom-10 "> <div class=" container"> <div class="headline-center"> <div class="row"> <h2>HOW TO ORDER</h2> </div> <div class="row"> <p>*Samples must arrive at the GENEWIZ New Jersey laboratory before 10:00 am EST to qualify for Same Day service. 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