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(PDF) Huiles de Chaulmoogra et de Gorli - Les premiers traitements antilépreux d’origine végétale | Anne Bargès - Academia.edu
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L’objectif de cette étude est de déterminer la diversité végétale impliquée dans le traitement des pathologies dermatologiques au Ferlo (Sénégal) et d’évaluer l’activité antimicrobienne des plantes les plus utilisées. Pour ce faire, un guide d’entretien semi directif a été soumis aux enquêtés, afin de recueillir la diversité des plantes utilisées au Ferlo dans le traitement des dermatoses. Des tests de micro dilution ont permis d’évaluer la concentration minimale inhibitrice (CMI) d’extraits de Sept (7) plantes contre une souche fongique (Candida albicans) et une bactérienne (Staphyloccocus aureus). Vingt-huit (28) espèces réparties dans 26 genres et 14 familles ont été recensées comme impliquées dans le traitement des affections dermatologiques. L’écorce est la partie la plus exploitée, pui...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Diversité Et Activité Antimicrobienne Des Plantes Impliquées Dans Le Traitement Des Affections Dermatologiques Chez Les Peul Et Les Wolof Du Ferlo Nord (Sénégal)","attachmentId":91204646,"attachmentType":"pdf","work_url":"https://www.academia.edu/86840345/Diversit%C3%A9_Et_Activit%C3%A9_Antimicrobienne_Des_Plantes_Impliqu%C3%A9es_Dans_Le_Traitement_Des_Affections_Dermatologiques_Chez_Les_Peul_Et_Les_Wolof_Du_Ferlo_Nord_S%C3%A9n%C3%A9gal_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/86840345/Diversit%C3%A9_Et_Activit%C3%A9_Antimicrobienne_Des_Plantes_Impliqu%C3%A9es_Dans_Le_Traitement_Des_Affections_Dermatologiques_Chez_Les_Peul_Et_Les_Wolof_Du_Ferlo_Nord_S%C3%A9n%C3%A9gal_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="89534979" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/89534979/Etude_compar%C3%A9e_de_l_efficacit%C3%A9_des_extraits_aqueux_de_feuilles_d_eucalyptus_Eucalyptus_camaldulensis_et_des_graines_de_neem_Azadirachta_indica_Juss_contre_les_principaux_ravageurs_de_chou">Etude comparée de l’efficacité des extraits aqueux de feuilles d’eucalyptus (Eucalyptus camaldulensis) et des graines de neem (Azadirachta indica Juss) contre les principaux ravageurs de chou</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="4871788" href="https://univ-na.academia.edu/KablanTano">Kablan Tano</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Biological and Chemical Sciences</p><p class="ds-related-work--abstract ds2-5-body-sm">Cette étude a été conduite afin d’évaluer ’efficacité des extraits aqueux de feuilles d’eucalyptus (Eucalyptus camaldulensis) et des graines de neem (Azadirachta indica Juss) contre les principaux ravageurs de chou. A cet effet, une parcelle disposée en 3 blocs complets, randomisés et équilibrés constitués de 4 parcelles élémentaires correspondant à 3 traitements et 1 témoin sans traitement a servi de dispositif expérimental. Après analyse des résultats, il ressort que l’extrait de graines de neem a un effet significatif sur tous les ravageurs ciblés. L’extrait de feuilles d’eucalyptus s’est montré inefficace sur Plutella xylostella et Brevicoryne brassicae. L’insecticide de synthèse a eu un effet immédiat sur Brevicoryne brassicae, un effet remarquable sur Spodoptera littoralis, mais s’est montré moins efficace sur Hellula undalis et Plutella xylostella. Les meilleurs rendements ont été obtenus sur les parcelles élémentaires (PE) traitées avec l’extrait aqueux de graines de neem et...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Etude comparée de l’efficacité des extraits aqueux de feuilles d’eucalyptus (Eucalyptus camaldulensis) et des graines de neem (Azadirachta indica Juss) contre les principaux ravageurs de chou","attachmentId":93322904,"attachmentType":"pdf","work_url":"https://www.academia.edu/89534979/Etude_compar%C3%A9e_de_l_efficacit%C3%A9_des_extraits_aqueux_de_feuilles_d_eucalyptus_Eucalyptus_camaldulensis_et_des_graines_de_neem_Azadirachta_indica_Juss_contre_les_principaux_ravageurs_de_chou","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/89534979/Etude_compar%C3%A9e_de_l_efficacit%C3%A9_des_extraits_aqueux_de_feuilles_d_eucalyptus_Eucalyptus_camaldulensis_et_des_graines_de_neem_Azadirachta_indica_Juss_contre_les_principaux_ravageurs_de_chou"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="43646213" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/43646213/Plantes_employ%C3%A9es_en_m%C3%A9decine_traditionnelle_contre_la_pathologie_h%C3%A9morro%C3%AFdaire_par_les_B%C3%A9t%C3%A9_de_la_sous_pr%C3%A9fecture_d_Ouragahio_d%C3%A9partement_de_Gagnoa_C%C3%B4te_d_Ivoire_">Plantes employées en médecine traditionnelle contre la pathologie hémorroïdaire par les Bété de la sous-préfecture d’Ouragahio, département de Gagnoa (Côte d’Ivoire).</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="46431041" href="https://fhb.academia.edu/SergeRolandSidio">Serge-Roland Sidio</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50075721" href="https://independent.academia.edu/AbrouNgouanEmmanuelJoel">Abrou N'gouan Emmanuel Joel</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Applied Biosciences, 2020</p><p class="ds-related-work--abstract ds2-5-body-sm">Objectifs : Cette étude a été réalisée avec pour objectif de recenser les connaissances ancestrales relatives au traitement traditionnel de la maladie hémorroïdaire auprès des tradipraticiens de santé de la sous-préfecture d’Ouragahio (Côte d’Ivoire) et ainsi contribuer à la valorisation de la médecine traditionnelle. Méthodologie et Résultats : Une collecte de données a été effectuée à travers des enquêtes ethnobotaniques grâce au concours de 33 guérisseurs et herboristes natifs de la localité visitée. Les informations recueillies ont été statistiquement traitées et ont permis de calculer des indices spécifiques. Il en ressort que dix-sept (17) espèces de plantes médicinales réparties en 15 genres appartenant à 11 familles sont recommandées pour la préparation de 19 recettes majoritairement monospécifiques (63,16%). Les Fabaceae forment la famille la plus représentée. Les feuilles (41,94%) sont les organes les plus sollicités. Le mode de récolte prépondérant est la cueillette (61,29%), la pulvérisation (45%) est la technique de préparation dominante et l’administration se fait majoritairement par voie orale (52,63%). Alchornea cordifolia est l’espèce la plus mentionnée (FC = 87,87%) et détient l’indice de consensus maximum de cette étude (IC = 0,76). Elle constitue avec Rhygiocarya racemiflora les plantes anti hémorroïdaires préférées des répondants (NP= 15,15%). Conclusion et Application des résultats : Les résultats de cette étude s’avèrent déterminantes étant donné qu’ils pourraient orienter des phytochimistes, des toxicologues et des pharmacologues sur de nouvelles pistes de recherches pouvant aboutir à la mise au point de médicaments traditionnels améliorés accessibles aux ménages à revenus modestes. Mots clés : Ethnobotanique, médecine traditionnelle, hémorroïdes, Ouragahio, Côte d’Ivoire.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Plantes employées en médecine traditionnelle contre\nla pathologie hémorroïdaire par les Bété de la sous-préfecture d’Ouragahio, département de Gagnoa (Côte\nd’Ivoire).","attachmentId":64229311,"attachmentType":"pdf","work_url":"https://www.academia.edu/43646213/Plantes_employ%C3%A9es_en_m%C3%A9decine_traditionnelle_contre_la_pathologie_h%C3%A9morro%C3%AFdaire_par_les_B%C3%A9t%C3%A9_de_la_sous_pr%C3%A9fecture_d_Ouragahio_d%C3%A9partement_de_Gagnoa_C%C3%B4te_d_Ivoire_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/43646213/Plantes_employ%C3%A9es_en_m%C3%A9decine_traditionnelle_contre_la_pathologie_h%C3%A9morro%C3%AFdaire_par_les_B%C3%A9t%C3%A9_de_la_sous_pr%C3%A9fecture_d_Ouragahio_d%C3%A9partement_de_Gagnoa_C%C3%B4te_d_Ivoire_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="4950666" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/4950666/Criblage_d_extraits_de_plantes_de_Madagascar_pour_recherche_d_activit%C3%A9_antipaludique_et_d_effet_potentialisateur_de_la_chloroquine">Criblage d’extraits de plantes de Madagascar pour recherche d’activité antipaludique et d’effet potentialisateur de la chloroquine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="3883403" href="https://independent.academia.edu/PhilippeRasoanaivo">Philippe Rasoanaivo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Ethnopharmacology, 1999</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Criblage d’extraits de plantes de Madagascar pour recherche d’activité antipaludique et d’effet potentialisateur de la chloroquine","attachmentId":36592226,"attachmentType":"pdf","work_url":"https://www.academia.edu/4950666/Criblage_d_extraits_de_plantes_de_Madagascar_pour_recherche_d_activit%C3%A9_antipaludique_et_d_effet_potentialisateur_de_la_chloroquine","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/4950666/Criblage_d_extraits_de_plantes_de_Madagascar_pour_recherche_d_activit%C3%A9_antipaludique_et_d_effet_potentialisateur_de_la_chloroquine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="110140041" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/110140041/Effet_des_extraits_du_th%C3%A9_de_Gambie_and_lt_i_and_gt_Lippia_multiflora_and_lt_i_and_gt_Moldenk_et_du_neem_and_lt_i_and_gt_Azadirachta_indica_and_lt_i_and_gt_A_Juss_sur_and_lt_i_and_gt_Helicoverpa_armigera_and_lt_i_and_gt_et_les_and_lt_i_and_gt_Thrips_and_lt_i_and_gt_de_la_tomate_and_lt_i_and_gt_Lycopersicon_esculentum_and_lt_i_and_gt_Mill_">Effet des extraits du thé de Gambie (&lt;i&gt;Lippia multiflora&lt;/i&gt; Moldenk) et du neem (&lt;i&gt;Azadirachta indica&lt;/i&gt; A. Juss.) sur&lt;i&gt; Helicoverpa armigera&lt;/i&gt; et les &lt;i&gt;Thrips&lt;/i&gt; de la tomate (&lt;i&gt;Lycopersicon esculentum &lt;/i&gt;Mill.)</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="56953097" href="https://independent.academia.edu/KoussaoSOME">Koussao SOME</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Applied Biosciences, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Effet des extraits du thé de Gambie (\u0026lt;i\u0026gt;Lippia multiflora\u0026lt;/i\u0026gt; Moldenk) et du neem (\u0026lt;i\u0026gt;Azadirachta indica\u0026lt;/i\u0026gt; A. Juss.) sur\u0026lt;i\u0026gt; Helicoverpa armigera\u0026lt;/i\u0026gt; et les \u0026lt;i\u0026gt;Thrips\u0026lt;/i\u0026gt; de la tomate (\u0026lt;i\u0026gt;Lycopersicon esculentum \u0026lt;/i\u0026gt;Mill.)","attachmentId":108049918,"attachmentType":"pdf","work_url":"https://www.academia.edu/110140041/Effet_des_extraits_du_th%C3%A9_de_Gambie_and_lt_i_and_gt_Lippia_multiflora_and_lt_i_and_gt_Moldenk_et_du_neem_and_lt_i_and_gt_Azadirachta_indica_and_lt_i_and_gt_A_Juss_sur_and_lt_i_and_gt_Helicoverpa_armigera_and_lt_i_and_gt_et_les_and_lt_i_and_gt_Thrips_and_lt_i_and_gt_de_la_tomate_and_lt_i_and_gt_Lycopersicon_esculentum_and_lt_i_and_gt_Mill_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/110140041/Effet_des_extraits_du_th%C3%A9_de_Gambie_and_lt_i_and_gt_Lippia_multiflora_and_lt_i_and_gt_Moldenk_et_du_neem_and_lt_i_and_gt_Azadirachta_indica_and_lt_i_and_gt_A_Juss_sur_and_lt_i_and_gt_Helicoverpa_armigera_and_lt_i_and_gt_et_les_and_lt_i_and_gt_Thrips_and_lt_i_and_gt_de_la_tomate_and_lt_i_and_gt_Lycopersicon_esculentum_and_lt_i_and_gt_Mill_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="85890812" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/85890812/Bioefficacit%C3%A9_des_poudres_et_des_huiles_essentielles_des_feuilles_de_Chenopodium_ambrosioides_et_Eucalyptus_saligna_%C3%A0_l_%C3%A9gard_de_la_bruche_du_ni%C3%A9b%C3%A9_">Bioefficacité des poudres et des huiles essentielles des feuilles de Chenopodium ambrosioides et Eucalyptus saligna à l 'égard de la bruche du niébé, …</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="48641902" href="https://independent.academia.edu/DFontem">D. Fontem</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Cahiers Agricultures, 2003</p><p class="ds-related-work--abstract ds2-5-body-sm">Résumé : Les feuilles de Chenopodium ambrosioides L. et Eucalyptus saligna Smith, utilisées pour la protection des grains stockés par les paysans dans les hauts plateaux de l&#x27;Ouest‐Cameroun, ont une forte teneur en huile essentielle. Les huiles volatiles extraites ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Bioefficacité des poudres et des huiles essentielles des feuilles de Chenopodium ambrosioides et Eucalyptus saligna à l 'égard de la bruche du niébé, …","attachmentId":90459148,"attachmentType":"pdf","work_url":"https://www.academia.edu/85890812/Bioefficacit%C3%A9_des_poudres_et_des_huiles_essentielles_des_feuilles_de_Chenopodium_ambrosioides_et_Eucalyptus_saligna_%C3%A0_l_%C3%A9gard_de_la_bruche_du_ni%C3%A9b%C3%A9_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/85890812/Bioefficacit%C3%A9_des_poudres_et_des_huiles_essentielles_des_feuilles_de_Chenopodium_ambrosioides_et_Eucalyptus_saligna_%C3%A0_l_%C3%A9gard_de_la_bruche_du_ni%C3%A9b%C3%A9_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="40959515" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/40959515/Activit%C3%A9s_Antiprolif%C3%A9rative_et_Antiradicalaire_dextraits_Aqueux_de_Quatre_Plantes_M%C3%A9dicinales_Congolaises">Activités Antiproliférative et Antiradicalaire d'extraits Aqueux de Quatre Plantes Médicinales Congolaises</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33384065" href="https://euinstitute.academia.edu/EuropeanScientificJournalESJ">European Scientific Journal ESJ</a></div><p class="ds-related-work--abstract ds2-5-body-sm">The purpose of this work is to evaluate antiprolifertive and DPPH radical scavenging activities of aqueous extracts from Morinda lucida Smith, Klainedoxa gabonensis Pierre ex Engl, Tephrosia vogelii Hook f and Nauclea latifolia Sm. The antiproliferative activity of the aqueous extract of each of the four species was evaluated in vitro on a cancer cell line (U87-MG) and a normal cell line (Hek-293) using the MTT assay. The antiradicalar activity was evaluated by measuring the scavenger capacity of the DPPH radical. Phytochemical analyzes of the extract were performed by thin layer chromatography and HPLC-PDA. The aqueous extracts of Klainedoxa gabonenis and Tephrosia vogelii showed antiproliferative activity against U87-MG cancer cells with IC50 values below 90 μg / ml. The aqueous extract of Klainedoxa gabonenis also showed remarkable antiradical activity (IC50 =4± 0,73 μg/ml). In addition, the treatment of U87-MG cancer cells by both the aqueous extract of Klainedoxa gabonensis (100 μg / ml) and by an MEK protein inhibitor (1 μM) causes a total suppression of U87-cell proliferation. MG (glioblastoma). HPLC-PDA analysis of the aqueous extract Klainedoxa gabonenis showed the presence of gallic acid compounds (41.9%) and Quercetin (2.17%).: Our study identified two medicinal plants with antiproliferative properties among the four Congolese herbal medicines evaluated, one with both anti-proliferative and antiradical properties.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Activités Antiproliférative et Antiradicalaire d'extraits Aqueux de Quatre Plantes Médicinales Congolaises","attachmentId":61244004,"attachmentType":"pdf","work_url":"https://www.academia.edu/40959515/Activit%C3%A9s_Antiprolif%C3%A9rative_et_Antiradicalaire_dextraits_Aqueux_de_Quatre_Plantes_M%C3%A9dicinales_Congolaises","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/40959515/Activit%C3%A9s_Antiprolif%C3%A9rative_et_Antiradicalaire_dextraits_Aqueux_de_Quatre_Plantes_M%C3%A9dicinales_Congolaises"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":104137636,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":104137636,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_104137636" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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