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Ltd. and Kalaivani R - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/38710595/Microbial_profile_of_neonatal_sepsis_and_antibiotic_resistance_from_a_tertiary_care_hospital_in_South_India" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '49879c2402910372f4abc62630a427bbe033d190'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732517457000); window.Aedu.timeDifference = new Date().getTime() - 1732517457000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Introduction: Neonatal sepsis is a major cause of neonatal mortality, the clinical outcome of which depends on early diagnosis and initiation of appropriate antibiotics. The emergence of multi-drug resistant strains has limited the choice of available antibiotics. Thus, antibiotic resistance pattern of pathogens iscritical for both therapy and infection control. Objective: To determine the etiological agents of neonatal sepsis and their antibiotic resistance pattern. Materials and Methods: In this study, all neonates with suspected sepsis, admitted to neonatal intensive care unit during January to December, 2014 were included. Aerobic blood culture was done using BACTEC FX system. Identification and antibiotic susceptibility testing of isolates from positive cultures was carried out. Results: Out of 522 neonates who developed clinical sepsis, 64 grew pathogens on blood culture. The most common organisms were coagulase negative Staphylococcus species (CONS)(32.8%), Klebsiella pneumoniae (18.7%), Escherichia coli (9.4%), Enterococcus faecalis (7.8%) and Candida species (7.8%). The gram negative isolates showed high resistance to ampicillin (90%), gentamicin (70%), ceftriaxone (66.7%), cotrimoxazole (56.7%), amikacin (53.3%) and ciprofloxacin (43.3%). In contrast, imipenem (16.7%), piperacillin-tazobactam (26.7%) and cefepime-tazobactam (0%) were effective with lower resistance rates. A large majority of the Enterobactericeae isolates (66.7%) were extended spectrum beta-lactamase producers. Among the gram positive isolates, resistance to penicillin, erythromycin and ciprofloxacin were 93.1%, 62.1%and 51.7% respectively. These strains showed uniform sensitivity to vancomycin, teicoplanin and linezolid. Conclusion: While CONS were the predominant isolate, gram negative bacilli and Enterococcus sp have shown high resistance to commonly used antibiotics. Low resistance was observed with Cefepime-tazobactam, imipenem (for gram-negative isolates) and vancomycin, teicoplanin and linezolid (for gram-positive isolates) in our study. Keywords: Neonatal sepsis, Bacteraemia, Antibiotic resistance, Blood culture.","author":[{"@context":"https://schema.org","@type":"Person","name":"IP Innovative Publication Pvt. Ltd."},{"@context":"https://schema.org","@type":"Person","name":"Kalaivani R"}],"contributor":[{"@context":"https://schema.org","@type":"Person","name":"Kalaivani R"}],"dateCreated":"2019-04-04","dateModified":null,"datePublished":"2019-01-01","headline":"Microbial profile of neonatal sepsis and antibiotic resistance from a tertiary care hospital in South India","inLanguage":"en","keywords":["Microbiology","Research in Microbiology","Indian Journal of Microbiology Research"],"locationCreated":null,"publication":"IP Innovative Publication Pvt. Ltd.","publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/38710595/Microbial_profile_of_neonatal_sepsis_and_antibiotic_resistance_from_a_tertiary_care_hospital_in_South_India","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":"innovativepublication"},{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/single_work_page/loswp-352e32ba4e89304dc0b4fa5b3952eef2198174c54cdb79066bc62e91c68a1a91.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/body-8d679e925718b5e8e4b18e9a4fab37f7eaa99e43386459376559080ac8f2856a.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-3cea6e0ad4715ed965c49bfb15dedfc632787b32ff6d8c3a474182b231146ab7.css" /><link rel="stylesheet" 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[{"id":58794354,"identifier":"Attachment_58794354","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":38710595,"created_at":"2019-04-04T03:30:00.769-07:00","from_world_paper_id":null,"updated_at":"2022-05-24T08:43:05.311-07:00","_data":{"doi":"10.18231/2394-5478.2019.0012","abstract":"Introduction: Neonatal sepsis is a major cause of neonatal mortality, the clinical outcome of which depends on early diagnosis and initiation of appropriate antibiotics. The emergence of multi-drug resistant strains has limited the choice of available antibiotics. Thus, antibiotic resistance pattern of pathogens iscritical for both therapy and infection control.\nObjective: To determine the etiological agents of neonatal sepsis and their antibiotic resistance pattern.\nMaterials and Methods: In this study, all neonates with suspected sepsis, admitted to neonatal intensive care unit during January to December, 2014 were included. Aerobic blood culture was done using BACTEC FX system. Identification and antibiotic susceptibility testing of isolates from positive cultures was carried out.\nResults: Out of 522 neonates who developed clinical sepsis, 64 grew pathogens on blood culture. The most common organisms were coagulase negative Staphylococcus species (CONS)(32.8%), Klebsiella pneumoniae (18.7%), Escherichia coli (9.4%), Enterococcus faecalis (7.8%) and Candida species (7.8%). The gram negative isolates showed high resistance to ampicillin (90%), gentamicin (70%), ceftriaxone (66.7%), cotrimoxazole (56.7%), amikacin (53.3%) and ciprofloxacin (43.3%). In contrast, imipenem (16.7%), piperacillin-tazobactam (26.7%) and cefepime-tazobactam (0%) were effective with lower resistance rates. A large majority of the Enterobactericeae isolates (66.7%) were extended spectrum beta-lactamase producers. Among the gram positive isolates, resistance to penicillin, erythromycin and ciprofloxacin were 93.1%, 62.1%and 51.7% respectively. These strains showed uniform sensitivity to vancomycin, teicoplanin and linezolid.\nConclusion: While CONS were the predominant isolate, gram negative bacilli and Enterococcus sp have shown high resistance to commonly used antibiotics. Low resistance was observed with Cefepime-tazobactam, imipenem (for gram-negative isolates) and vancomycin, teicoplanin and linezolid (for gram-positive isolates) in our study.\nKeywords: Neonatal sepsis, Bacteraemia, Antibiotic resistance, Blood culture.","publication_date":"2019,,","publication_name":"IP Innovative Publication Pvt. Ltd."},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Microbial profile of neonatal sepsis and antibiotic resistance from a tertiary care hospital in South India","broadcastable":true,"draft":false,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [108820338,27377481]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":58794354,"attachmentType":"pdf"}"><img alt="First page of “Microbial profile of neonatal sepsis and antibiotic resistance from a tertiary care hospital in South India”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/58794354/mini_magick20190404-27995-q3u5hg.png?1554383858" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Microbial profile of neonatal sepsis and antibiotic resistance from a tertiary care hospital in South India</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="108820338" href="https://independent.academia.edu/KalaivaniR6"><img alt="Profile image of Kalaivani R" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Kalaivani R</a><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="27377481" href="https://innovativepublication.academia.edu/IP"><img alt="Profile image of IP Innovative Publication Pvt. Ltd." class="ds-work-card--author-avatar" src="https://0.academia-photos.com/27377481/8351640/25499110/s65_ip_innovative.publication_pvt._ltd..png" />IP Innovative Publication Pvt. Ltd.</a></div><p class="ds-work-card--detail ds2-5-body-sm">2019, IP Innovative Publication Pvt. Ltd.</p><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Introduction: Neonatal sepsis is a major cause of neonatal mortality, the clinical outcome of which depends on early diagnosis and initiation of appropriate antibiotics. The emergence of multi-drug resistant strains has limited the choice of available antibiotics. Thus, antibiotic resistance pattern of pathogens iscritical for both therapy and infection control. Objective: To determine the etiological agents of neonatal sepsis and their antibiotic resistance pattern. Materials and Methods: In this study, all neonates with suspected sepsis, admitted to neonatal intensive care unit during January to December, 2014 were included. Aerobic blood culture was done using BACTEC FX system. Identification and antibiotic susceptibility testing of isolates from positive cultures was carried out. Results: Out of 522 neonates who developed clinical sepsis, 64 grew pathogens on blood culture. The most common organisms were coagulase negative Staphylococcus species (CONS)(32.8%), Klebsiella pneumoniae (18.7%), Escherichia coli (9.4%), Enterococcus faecalis (7.8%) and Candida species (7.8%). The gram negative isolates showed high resistance to ampicillin (90%), gentamicin (70%), ceftriaxone (66.7%), cotrimoxazole (56.7%), amikacin (53.3%) and ciprofloxacin (43.3%). In contrast, imipenem (16.7%), piperacillin-tazobactam (26.7%) and cefepime-tazobactam (0%) were effective with lower resistance rates. A large majority of the Enterobactericeae isolates (66.7%) were extended spectrum beta-lactamase producers. Among the gram positive isolates, resistance to penicillin, erythromycin and ciprofloxacin were 93.1%, 62.1%and 51.7% respectively. These strains showed uniform sensitivity to vancomycin, teicoplanin and linezolid. Conclusion: While CONS were the predominant isolate, gram negative bacilli and Enterococcus sp have shown high resistance to commonly used antibiotics. Low resistance was observed with Cefepime-tazobactam, imipenem (for gram-negative isolates) and vancomycin, teicoplanin and linezolid (for gram-positive isolates) in our study. Keywords: Neonatal sepsis, Bacteraemia, Antibiotic resistance, Blood culture.</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":58794354,"attachmentType":"pdf","workUrl":"https://www.academia.edu/38710595/Microbial_profile_of_neonatal_sepsis_and_antibiotic_resistance_from_a_tertiary_care_hospital_in_South_India"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":58794354,"attachmentType":"pdf","workUrl":"https://www.academia.edu/38710595/Microbial_profile_of_neonatal_sepsis_and_antibiotic_resistance_from_a_tertiary_care_hospital_in_South_India"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" 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href="https://independent.academia.edu/ArunSingh811">Arun Singh</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Paediatrics and International Child Health, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Multi-drug-resistant, non-fermenting, gram-negative bacilli in neonatal sepsis in Kolkata, India: a 4-year study","attachmentId":102421162,"attachmentType":"pdf","work_url":"https://www.academia.edu/102052591/Multi_drug_resistant_non_fermenting_gram_negative_bacilli_in_neonatal_sepsis_in_Kolkata_India_a_4_year_study","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/102052591/Multi_drug_resistant_non_fermenting_gram_negative_bacilli_in_neonatal_sepsis_in_Kolkata_India_a_4_year_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="115672448" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/115672448/Blood_culture_result_profile_and_antimicrobial_resistance_pattern_a_report_from_neonatal_intensive_care_unit_NICU_Asella_teaching_and_referral_hospital_Asella_south_East_Ethiopia">Blood culture result profile and antimicrobial resistance pattern: a report from neonatal intensive care unit (NICU), Asella teaching and referral hospital, Asella, south East Ethiopia</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="25555479" href="https://independent.academia.edu/SileshiAbdissa">Sileshi Abdissa</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Antimicrobial Resistance &amp; Infection Control, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Blood culture result profile and antimicrobial resistance pattern: a report from neonatal intensive care unit (NICU), Asella teaching and referral hospital, Asella, south East Ethiopia","attachmentId":112014579,"attachmentType":"pdf","work_url":"https://www.academia.edu/115672448/Blood_culture_result_profile_and_antimicrobial_resistance_pattern_a_report_from_neonatal_intensive_care_unit_NICU_Asella_teaching_and_referral_hospital_Asella_south_East_Ethiopia","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/115672448/Blood_culture_result_profile_and_antimicrobial_resistance_pattern_a_report_from_neonatal_intensive_care_unit_NICU_Asella_teaching_and_referral_hospital_Asella_south_East_Ethiopia"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="56927124" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/56927124/A_Profile_of_Microbial_Isolates_and_Antibiotic_Susceptibility_Patterns_in_Neonatal_Sepsis_at_a_Tertiary_Care_Centre_in_South_India_A_Post_HOC_Analysis">A Profile of Microbial Isolates and Antibiotic Susceptibility Patterns in Neonatal Sepsis at a Tertiary Care Centre in South India - A Post HOC Analysis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="26200429" href="https://independent.academia.edu/SantoshKumarKamalakannan">Santosh Kumar Kamalakannan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Progressing Aspects in Pediatrics and Neonatology</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A Profile of Microbial Isolates and Antibiotic Susceptibility Patterns in Neonatal Sepsis at a Tertiary Care Centre in South India - A Post HOC Analysis","attachmentId":72073767,"attachmentType":"pdf","work_url":"https://www.academia.edu/56927124/A_Profile_of_Microbial_Isolates_and_Antibiotic_Susceptibility_Patterns_in_Neonatal_Sepsis_at_a_Tertiary_Care_Centre_in_South_India_A_Post_HOC_Analysis","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/56927124/A_Profile_of_Microbial_Isolates_and_Antibiotic_Susceptibility_Patterns_in_Neonatal_Sepsis_at_a_Tertiary_Care_Centre_in_South_India_A_Post_HOC_Analysis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="99081935" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/99081935/Neonatal_Sepsis_A_Study_on_Isolated_Pathogens_and_Their_Susceptibility_Pattern_at_Tertiary_Care_Hospital_in_Rural_Setting">Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="81067189" href="https://independent.academia.edu/NagaSriLathaBathala">Naga Sri Latha Bathala</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting","attachmentId":100263439,"attachmentType":"pdf","work_url":"https://www.academia.edu/99081935/Neonatal_Sepsis_A_Study_on_Isolated_Pathogens_and_Their_Susceptibility_Pattern_at_Tertiary_Care_Hospital_in_Rural_Setting","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/99081935/Neonatal_Sepsis_A_Study_on_Isolated_Pathogens_and_Their_Susceptibility_Pattern_at_Tertiary_Care_Hospital_in_Rural_Setting"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="106328797" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/106328797/Neonatal_Sepsis_Antibiotic_Sensitivity_and_Resistance_Pattern_of_Most_Common_Isolated_Pathogens_in_a_Neonatal_Intensive_Care_Unit_of_a_Tertiary_Care_Hospital">Neonatal Sepsis: Antibiotic Sensitivity and Resistance Pattern of Most Common Isolated Pathogens in a Neonatal Intensive Care Unit of a Tertiary Care Hospital</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="252644365" href="https://independent.academia.edu/PrakashWaghmare19">Prakash Waghmare</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Current Microbiology and Applied Sciences, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Neonatal Sepsis: Antibiotic Sensitivity and Resistance Pattern of Most Common Isolated Pathogens in a Neonatal Intensive Care Unit of a Tertiary Care Hospital","attachmentId":105556173,"attachmentType":"pdf","work_url":"https://www.academia.edu/106328797/Neonatal_Sepsis_Antibiotic_Sensitivity_and_Resistance_Pattern_of_Most_Common_Isolated_Pathogens_in_a_Neonatal_Intensive_Care_Unit_of_a_Tertiary_Care_Hospital","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/106328797/Neonatal_Sepsis_Antibiotic_Sensitivity_and_Resistance_Pattern_of_Most_Common_Isolated_Pathogens_in_a_Neonatal_Intensive_Care_Unit_of_a_Tertiary_Care_Hospital"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="69757376" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/69757376/Causative_bacteria_and_antibiotic_resistance_in_neonatal_sepsis">Causative bacteria and antibiotic resistance in neonatal sepsis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="128412677" href="https://independent.academia.edu/AneesUrrehman35">Anees Ur rehman</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Ayub Medical College, Abbottabad : JAMC</p><p class="ds-related-work--abstract ds2-5-body-sm">Neonatal sepsis is characterised by bacteraemia and clinical symptoms caused by microorganisms and their toxic products. Gram negative bacteria are the commonest causes of neonatal Sepsis. The resistance to the commonly used antibiotics is alarmingly high. The major reason for emerging resistance against antibiotics is that doctors often do not take blood cultures before starting antibiotics. We have carried out this study to find out various bacteria causing neonatal sepsis and their susceptibility to antibiotics for better management of neonatal sepsis. A total of 130 neonates with sepsis who were found to be blood culture positive were taken in this study. Culture/sensitivity was done, isolated organisms identified and their sensitivity/resistance was noted against different antibiotics. Data were arranged in terms of frequencies and percentage. Out of 130 culture proven cases of neonatal sepsis, gram negative bacteria were found in 71 (54.6%) cases and gram positive bacteria in ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Causative bacteria and antibiotic resistance in neonatal sepsis","attachmentId":79730149,"attachmentType":"pdf","work_url":"https://www.academia.edu/69757376/Causative_bacteria_and_antibiotic_resistance_in_neonatal_sepsis","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/69757376/Causative_bacteria_and_antibiotic_resistance_in_neonatal_sepsis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":58794354,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":58794354,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_58794354" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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class="ds-related-work--metadata ds2-5-body-xs">International Journal of Contemporary Medical Research [IJCMR], 2018</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Bacteriology and Antibiotic Resistance Pattern in Neonatal Septicemia","attachmentId":100672163,"attachmentType":"pdf","work_url":"https://www.academia.edu/99635194/Bacteriology_and_Antibiotic_Resistance_Pattern_in_Neonatal_Septicemia","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/99635194/Bacteriology_and_Antibiotic_Resistance_Pattern_in_Neonatal_Septicemia"><span class="ds2-5-text-link__content">View 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href="https://www.academia.edu/96433787/Bacterial_profile_and_drug_resistance_patterns_in_neonates_admitted_with_sepsis_to_a_tertiary_teaching_hospital_in_Ethiopia"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="14" data-entity-id="113412960" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/113412960/Neonatal_Sepsis_Clinical_Spectrum_Bacteriological_Profile_and_Antibiotic_Sensitivity_Patterns_in_Neonatal_Intensive_Care_Unit_in_a_Tertiary_Care_Hospital">Neonatal Sepsis: Clinical Spectrum, Bacteriological Profile and Antibiotic Sensitivity Patterns in Neonatal Intensive Care Unit in a Tertiary Care Hospital</a><div class="ds-related-work--metadata"><a 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