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(PDF) Neonatal sepsis: causative bacteria and their resistance to antibiotics | Umar Hayat - Academia.edu

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The objective of this study was to determine the causative bacteria and level of their resistance to commonly used antibiotics. This" /> <meta name="twitter:image" content="https://0.academia-photos.com/226044839/83140307/71755599/s200_umar.hayat.jpeg" /> <meta property="fb:app_id" content="2369844204" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.academia.edu/93608764/Neonatal_sepsis_causative_bacteria_and_their_resistance_to_antibiotics" /> <meta property="og:title" content="Neonatal sepsis: causative bacteria and their resistance to antibiotics" /> <meta property="og:image" content="http://a.academia-assets.com/images/open-graph-icons/fb-paper.gif" /> <meta property="og:description" content="Neonatal sepsis is one of the major causes of neonatal morbidity and mortality, particularly in developing countries. The objective of this study was to determine the causative bacteria and level of their resistance to commonly used antibiotics. This" /> <meta property="article:author" content="https://independent.academia.edu/UmarHayat197" /> <meta name="description" content="Neonatal sepsis is one of the major causes of neonatal morbidity and mortality, particularly in developing countries. The objective of this study was to determine the causative bacteria and level of their resistance to commonly used antibiotics. This" /> <title>(PDF) Neonatal sepsis: causative bacteria and their resistance to antibiotics | Umar Hayat - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/93608764/Neonatal_sepsis_causative_bacteria_and_their_resistance_to_antibiotics" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '92477ec68c09d28ae4730a4143c926f074776319'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732842688000); window.Aedu.timeDifference = new Date().getTime() - 1732842688000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Neonatal sepsis is one of the major causes of neonatal morbidity and mortality, particularly in developing countries. The objective of this study was to determine the causative bacteria and level of their resistance to commonly used antibiotics. This descriptive study was carried out at Ayub Teaching Hospital, Abbottabad from April 2009 to January 2010. All neonates of either gender admitted in neonatology unit with clinical sepsis and positive blood culture were included in the study. Neonatal period was defined as 28 days of life at term and up to 44 weeks of gestational age in preterm babies. One hundred and thirty neonates of either gender were studied during the period. Blood sample for culture was taken from a peripheral vein or an artery ensuring standard anti-septic measures. BACTEC technique was used for obtaining bacterial growth and drug sensitivity after incubation of 24-48 hours. Second blood culture was also performed in few cases which were not showing improvement aft...","author":[{"@context":"https://schema.org","@type":"Person","name":"Umar Hayat"}],"contributor":[],"dateCreated":"2022-12-24","dateModified":null,"datePublished":null,"headline":"Neonatal sepsis: causative bacteria and their resistance to antibiotics","inLanguage":"en","keywords":["Pakistan","Medicine","Humans","Escherichia coli","Female","Male","Microbial genetic and drug resistance","Staphylococcus aureus","Sepsis","Antibiotics","Newborn Infant","Anti-Bacterial Agents","Neonatal Sepsis","Cefotaxime","Ampicillin","Blood Culture","Gentamicin"],"locationCreated":null,"publication":"Journal of Ayub Medical College, Abbottabad : 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The objective of this study was to determine the causative bacteria and level of their resistance to commonly used antibiotics. This descriptive study was carried out at Ayub Teaching Hospital, Abbottabad from April 2009 to January 2010. All neonates of either gender admitted in neonatology unit with clinical sepsis and positive blood culture were included in the study. Neonatal period was defined as 28 days of life at term and up to 44 weeks of gestational age in preterm babies. One hundred and thirty neonates of either gender were studied during the period. Blood sample for culture was taken from a peripheral vein or an artery ensuring standard anti-septic measures. BACTEC technique was used for obtaining bacterial growth and drug sensitivity after incubation of 24-48 hours. Second blood culture was also performed in few cases which were not showing improvement aft...","publication_name":"Journal of Ayub Medical College, Abbottabad : JAMC"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Neonatal sepsis: causative bacteria and their resistance to antibiotics","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [226044839]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;swp-splash-paper-cover&quot;,&quot;attachmentId&quot;:96299742,&quot;attachmentType&quot;:&quot;pdf&quot;}"><img alt="First page of “Neonatal sepsis: causative bacteria and their resistance to antibiotics”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/96299742/mini_magick20221224-1-v8tvgv.png?1671901874" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Neonatal sepsis: causative bacteria and their resistance to antibiotics</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="226044839" href="https://independent.academia.edu/UmarHayat197"><img alt="Profile image of Umar Hayat" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/226044839/83140307/71755599/s65_umar.hayat.jpeg" />Umar Hayat</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">Journal of Ayub Medical College, Abbottabad : JAMC</p></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Neonatal sepsis is one of the major causes of neonatal morbidity and mortality, particularly in developing countries. The objective of this study was to determine the causative bacteria and level of their resistance to commonly used antibiotics. This descriptive study was carried out at Ayub Teaching Hospital, Abbottabad from April 2009 to January 2010. All neonates of either gender admitted in neonatology unit with clinical sepsis and positive blood culture were included in the study. Neonatal period was defined as 28 days of life at term and up to 44 weeks of gestational age in preterm babies. One hundred and thirty neonates of either gender were studied during the period. Blood sample for culture was taken from a peripheral vein or an artery ensuring standard anti-septic measures. BACTEC technique was used for obtaining bacterial growth and drug sensitivity after incubation of 24-48 hours. Second blood culture was also performed in few cases which were not showing improvement aft...</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--work-card&quot;,&quot;attachmentId&quot;:96299742,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:&quot;https://www.academia.edu/93608764/Neonatal_sepsis_causative_bacteria_and_their_resistance_to_antibiotics&quot;}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--work-card&quot;,&quot;attachmentId&quot;:96299742,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:&quot;https://www.academia.edu/93608764/Neonatal_sepsis_causative_bacteria_and_their_resistance_to_antibiotics&quot;}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="96299742" data-landing_url="https://www.academia.edu/93608764/Neonatal_sepsis_causative_bacteria_and_their_resistance_to_antibiotics" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="50429874" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/50429874/Neonatal_Bacterial_Sepsis_and_Its_Susceptibility_Pattern_in_Neonatal_Care_Unit_of_Tertiary_Care_Hospital">Neonatal Bacterial Sepsis and Its Susceptibility Pattern in Neonatal Care Unit of Tertiary Care Hospital</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="129614317" href="https://independent.academia.edu/AltafAliMangi">Altaf Ali Mangi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Pharmaceutical Research International</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: The drug resistance and pathogens are different in various Hospitals of any country. Very high resistance pattern is observed nowadays to the frequently used antibiotics. The important observation has been noted that most of the doctors do not obtain blood cultures before start of the antibiotics, which becomes competent source of resistance. For the same purpose, this study has been done to find out the responsible microbes causing ailment and their susceptibility towards antibiotics to plan early and effective management. Materials and Methods: A number of 100 new borns admitted in the NICU CMC Children Hospital Larkana with signs and symptoms of sepsis were included in this research work. The study will help in provision of a comprehensive record on microorganisms causing sepsis in the neonates and their antibiotic sensitivity. The epidemiology and presence of neonatal sepsis in particular area makes it more easy and convenient to implement the rationale of empirical ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal Bacterial Sepsis and Its Susceptibility Pattern in Neonatal Care Unit of Tertiary Care Hospital&quot;,&quot;attachmentId&quot;:68422111,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/50429874/Neonatal_Bacterial_Sepsis_and_Its_Susceptibility_Pattern_in_Neonatal_Care_Unit_of_Tertiary_Care_Hospital&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/50429874/Neonatal_Bacterial_Sepsis_and_Its_Susceptibility_Pattern_in_Neonatal_Care_Unit_of_Tertiary_Care_Hospital"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="53279566" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/53279566/Neonatal_Sepsis_Common_Bacterial_Isolates_and_Their_Antimicrobial_Susceptibility_Patterns_in_Neonatal_Intensive_Care_Unit_Islamabad">Neonatal Sepsis; Common Bacterial Isolates and Their Antimicrobial Susceptibility Patterns in Neonatal Intensive Care Unit, Islamabad</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="81141096" href="https://pimshospitalislamabadpakistan.academia.edu/DrShafatKhatoon">Dr Shafat Khatoon</a></div><p class="ds-related-work--metadata ds2-5-body-xs">THE PROFESSIONAL MEDICAL JOURNAL, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal Sepsis; Common Bacterial Isolates and Their Antimicrobial Susceptibility Patterns in Neonatal Intensive Care Unit, Islamabad&quot;,&quot;attachmentId&quot;:70191350,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/53279566/Neonatal_Sepsis_Common_Bacterial_Isolates_and_Their_Antimicrobial_Susceptibility_Patterns_in_Neonatal_Intensive_Care_Unit_Islamabad&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/53279566/Neonatal_Sepsis_Common_Bacterial_Isolates_and_Their_Antimicrobial_Susceptibility_Patterns_in_Neonatal_Intensive_Care_Unit_Islamabad"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="65848151" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/65848151/Bacterial_Etiology_of_Neonatal_Sepsis_Antibiotic_Susceptibility_Profile_and_Associated_Factors_at_Burdwan_Medical_College_Burdwan_West_Bengal_India">Bacterial Etiology of Neonatal Sepsis, Antibiotic Susceptibility Profile, and Associated Factors at Burdwan Medical College, Burdwan, West Bengal, India</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="140313422" href="https://independent.academia.edu/KUHUPAL">KUHU PAL</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective Neonatal sepsis remains to be a major cause of neonatal mortality and morbidity in developing countries like India. This study was aimed to identify the bacterial isolates and study antimicrobial profile among admitted babies with neonatal sepsis. Methods A cross-sectional retrospective study was conducted in the sick neonatal wards and neonatal intensive care unit of Burdwan Medical College from March 2017 to February 2018. A total of 299 neonates suspected of neonatal sepsis was evaluated. Diagnosis of neonatal sepsis was made through positive blood culture. Positive samples were subcultured on specific media like blood, chocolate agar, nutrient, Muller–Hinton agar, and MacConkey plates, and the organisms were identified by gram staining and biochemical reactions. Antibiotic susceptibility was tested by Kirby–Bauer disc diffusion method. Results Overall, 118 blood cultures out of 299 patients (39.46%) were bacteria-positive. Of these, 31.3% cases had early-onset septicem...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Bacterial Etiology of Neonatal Sepsis, Antibiotic Susceptibility Profile, and Associated Factors at Burdwan Medical College, Burdwan, West Bengal, India&quot;,&quot;attachmentId&quot;:77267490,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/65848151/Bacterial_Etiology_of_Neonatal_Sepsis_Antibiotic_Susceptibility_Profile_and_Associated_Factors_at_Burdwan_Medical_College_Burdwan_West_Bengal_India&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/65848151/Bacterial_Etiology_of_Neonatal_Sepsis_Antibiotic_Susceptibility_Profile_and_Associated_Factors_at_Burdwan_Medical_College_Burdwan_West_Bengal_India"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="55108193" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/55108193/Clinical_and_bacteriological_profile_of_neonatal_sepsis_with_emerging_resistance_patterns">Clinical and bacteriological profile of neonatal sepsis with emerging resistance patterns</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="46293114" href="https://independent.academia.edu/DhanRajBagri">Dhan Raj Bagri</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Contemporary Pediatrics</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: The present study was designed to evaluate the clinical spectrum, bacteriological profile, antibiotic sensitivity pattern and mortality due to neonatal septicemia in neonates admitted in neonatal units attached to the SMS Medical College, Jaipur.Methods: In born and out born babies of postnatal age up to 28 days who were bacteriological proven cases of septicemia were subjected to history, clinical examination and laboratory evaluation and data were analyzed statistically.Results: Out of 150 cases 67.33% neonates were preterm and 77.33% were low birth weight neonates. Gram negative organisms were most common cause of septicemia (66.6%), Both the Gram negative and Gram positive organisms were sensitive to piperacillin-tazobactam, linezolid, fosfomycin, teicoplanin, polymyxin B, colistin, ofloxacin. Both the Gram negative and Gram positive organisms were resistant against cephalosporins, ampicillin, Amoxyclav, cotrimoxazole. Gram negative isolates were most sensitive to Po...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Clinical and bacteriological profile of neonatal sepsis with emerging resistance patterns&quot;,&quot;attachmentId&quot;:71139439,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/55108193/Clinical_and_bacteriological_profile_of_neonatal_sepsis_with_emerging_resistance_patterns&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/55108193/Clinical_and_bacteriological_profile_of_neonatal_sepsis_with_emerging_resistance_patterns"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="106328797" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/106328797/Neonatal_Sepsis_Antibiotic_Sensitivity_and_Resistance_Pattern_of_Most_Common_Isolated_Pathogens_in_a_Neonatal_Intensive_Care_Unit_of_a_Tertiary_Care_Hospital">Neonatal Sepsis: Antibiotic Sensitivity and Resistance Pattern of Most Common Isolated Pathogens in a Neonatal Intensive Care Unit of a Tertiary Care Hospital</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="252644365" href="https://independent.academia.edu/PrakashWaghmare19">Prakash Waghmare</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Current Microbiology and Applied Sciences, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal Sepsis: Antibiotic Sensitivity and Resistance Pattern of Most Common Isolated Pathogens in a Neonatal Intensive Care Unit of a Tertiary Care Hospital&quot;,&quot;attachmentId&quot;:105556173,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/106328797/Neonatal_Sepsis_Antibiotic_Sensitivity_and_Resistance_Pattern_of_Most_Common_Isolated_Pathogens_in_a_Neonatal_Intensive_Care_Unit_of_a_Tertiary_Care_Hospital&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/106328797/Neonatal_Sepsis_Antibiotic_Sensitivity_and_Resistance_Pattern_of_Most_Common_Isolated_Pathogens_in_a_Neonatal_Intensive_Care_Unit_of_a_Tertiary_Care_Hospital"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="114605006" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/114605006/Neonatal_sepsis_high_antibiotic_resistance_of_the_bacterial_pathogens_in_a_neonatal_intensive_care_unit_of_a_tertiary_care_hospital">Neonatal sepsis: high antibiotic resistance of the bacterial pathogens in a neonatal intensive care unit of a tertiary care hospital</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7844421" href="https://independent.academia.edu/AbidMahmood2">Abid Mahmood</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of clinical neonatology, 2012</p><p class="ds-related-work--abstract ds2-5-body-sm">To study the bacterial pathogens causing neonatal sepsis and their sensitivity pattern so that guidelines can be prepared for empirical antibiotic therapy. We conducted a prospective analysis of all the cases admitted to the neonatal intensive care unit (NICU) of a tertiary care hospital and studied the culture and sensitivity pattern of organisms isolated. The neonates who presented with signs and symptoms of septicemia, with/without pneumonia and/or meningitis were studied and a detailed record of the maturity, age at onset, sex, birth weight (weight on admission for home deliveries), symptoms and signs along with the maternal risk factors was made. The cases with suspect sepsis were screened using various screening markers. Blood culture was done in all the cases, while cerebrospinal fluid was analysed only in those indicated. Sensitivity of the isolated organism was tested by Kirby Bauer disc diffusion techniques and various drug resistance mechanisms were studied. Out of the 19...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal sepsis: high antibiotic resistance of the bacterial pathogens in a neonatal intensive care unit of a tertiary care hospital&quot;,&quot;attachmentId&quot;:111259631,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/114605006/Neonatal_sepsis_high_antibiotic_resistance_of_the_bacterial_pathogens_in_a_neonatal_intensive_care_unit_of_a_tertiary_care_hospital&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/114605006/Neonatal_sepsis_high_antibiotic_resistance_of_the_bacterial_pathogens_in_a_neonatal_intensive_care_unit_of_a_tertiary_care_hospital"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="101275033" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/101275033/Bacteriological_Profile_and_Antibiotic_Susceptibility_Pattern_of_Isolates_in_Neonatal_Sepsis">Bacteriological Profile and Antibiotic Susceptibility Pattern of Isolates in Neonatal Sepsis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="268415953" href="https://independent.academia.edu/ShaistaEhsan">Shaista Ehsan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pakistan Journal of Health Sciences</p><p class="ds-related-work--abstract ds2-5-body-sm">Sepsis in newborns is a serious medical condition having a high mortality. Pakistan and other developing countries have a high burden of neonatal sepsis. Objectives: To determine the bacterial spectrum and antibiotic activity pattern in neonatal sepsis. Methods: This retrospective cross-sectional research was performed at the Pediatrics Unit of Ziauddin University Hospital Karachi from 1st June 2022 till 1st December 2022. A total of 120 medical records of neonates admitted with the clinical suspicion of sepsis were reviewed. Non-probability convenience sampling technique was used. Data regarding clinical characteristics of neonates, type of bacteria isolated and antibiotic susceptibility results were recorded. SPSS version 20 was used for statistical analysis. The results were written as frequencies / percentages. Results: Neonatal sepsis was suspected in 120 newborns but blood culture-proven infection was present in 32 (13.3%) neonates with 23(71.8%) having early -onset sepsis. T...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Bacteriological Profile and Antibiotic Susceptibility Pattern of Isolates in Neonatal Sepsis&quot;,&quot;attachmentId&quot;:101861251,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/101275033/Bacteriological_Profile_and_Antibiotic_Susceptibility_Pattern_of_Isolates_in_Neonatal_Sepsis&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/101275033/Bacteriological_Profile_and_Antibiotic_Susceptibility_Pattern_of_Isolates_in_Neonatal_Sepsis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="31781770" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/31781770/Neonatal_Sepsis_Bacteria_and_their_Susceptibility_Pattern_towards_Antibiotics_in_Neonatal_Intensive_Care_Unit">Neonatal Sepsis&quot;: Bacteria &amp; their Susceptibility Pattern towards Antibiotics in Neonatal Intensive Care Unit</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58496371" href="https://friends.academia.edu/deeptisharma">deepti sharma</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of clinical and diagnostic research : JCDR, 2013</p><p class="ds-related-work--abstract ds2-5-body-sm">Neonatal sepsis is one of the most common causes of neonatal mortality and morbidity, particularly in the developing countries. Its causative bacteria and their respective sensitivity patterns are different in each hospital and region. The objective of this study was to determine the causative bacteria and pattern of susceptibility to antibiotics in NICU of a tertiary care centre, which in turn may help in implementation of empirical therapy. This prospective study was carried out at a medical college during the period from 1st April 2011 to 31st March 2013. A total of 364 cases of suspected sepsis were admitted in our NICU during the mentioned period. Out of which, 137 cases were positive for culture. All the neonates of suspected sepsis were screened by using a panel consisting of CRP, ANC, I/T ratio, micro ESR and culture and sensitivity. A total of 137 cultures were found to be positive out of 364 cases. The most common organism isolated was Staphylococcus aureus (37.22%) follow...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal Sepsis\&quot;: Bacteria \u0026 their Susceptibility Pattern towards Antibiotics in Neonatal Intensive Care Unit&quot;,&quot;attachmentId&quot;:52083702,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/31781770/Neonatal_Sepsis_Bacteria_and_their_Susceptibility_Pattern_towards_Antibiotics_in_Neonatal_Intensive_Care_Unit&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/31781770/Neonatal_Sepsis_Bacteria_and_their_Susceptibility_Pattern_towards_Antibiotics_in_Neonatal_Intensive_Care_Unit"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="69757376" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/69757376/Causative_bacteria_and_antibiotic_resistance_in_neonatal_sepsis">Causative bacteria and antibiotic resistance in neonatal sepsis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="128412677" href="https://independent.academia.edu/AneesUrrehman35">Anees Ur rehman</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Ayub Medical College, Abbottabad : JAMC</p><p class="ds-related-work--abstract ds2-5-body-sm">Neonatal sepsis is characterised by bacteraemia and clinical symptoms caused by microorganisms and their toxic products. Gram negative bacteria are the commonest causes of neonatal Sepsis. The resistance to the commonly used antibiotics is alarmingly high. The major reason for emerging resistance against antibiotics is that doctors often do not take blood cultures before starting antibiotics. We have carried out this study to find out various bacteria causing neonatal sepsis and their susceptibility to antibiotics for better management of neonatal sepsis. A total of 130 neonates with sepsis who were found to be blood culture positive were taken in this study. Culture/sensitivity was done, isolated organisms identified and their sensitivity/resistance was noted against different antibiotics. Data were arranged in terms of frequencies and percentage. Out of 130 culture proven cases of neonatal sepsis, gram negative bacteria were found in 71 (54.6%) cases and gram positive bacteria in ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Causative bacteria and antibiotic resistance in neonatal sepsis&quot;,&quot;attachmentId&quot;:79730149,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/69757376/Causative_bacteria_and_antibiotic_resistance_in_neonatal_sepsis&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/69757376/Causative_bacteria_and_antibiotic_resistance_in_neonatal_sepsis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="74947735" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/74947735/Bacteriological_profile_and_antibiotic_susceptibility_of_neonatal_sepsis_in_neonatal_intensive_care_unit_of_a_tertiary_care_medical_institute_of_Eastern_India_A_retrospective_cross_sectional_study">Bacteriological profile and antibiotic susceptibility of neonatal sepsis in neonatal intensive care unit of a tertiary care medical institute of Eastern India: A retrospective cross-sectional study</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="136409877" href="https://independent.academia.edu/SunilKishore2">Sunil Kishore</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: According to WHO neonatal sepsis is the most important reason for morbidity and mortality in the neonatal period. By the knowledge of bacteriological flora and their antibiotic susceptibility pattern, we can decrease the mortality and morbidity. Multidrug antibiotic resistance is also increasing day by day in neonatal intensive care units. So our aim of the study was to find out the bacteriological profile and antibiotic susceptibility pattern in the NICU of Indira Gandhi Institute of Medical Sciences, a tertiary teaching hospital in Bihar. Materials and Methods: A retrospective analysis of all blood culture positive sepsis cases among neonates admitted to the neonatal intensive care unit of Indira Gandhi Institute of Medical Sciences Patna Bihar from Feb16, 2019, and Feb 15, 2020, was attempted. Neonate with a risk factor of sepsis having positive blood culture was analyzed bacteriologically and antibiotic sensitivity pattern was identified. Results: Out of 168 neonates...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Bacteriological profile and antibiotic susceptibility of neonatal sepsis in neonatal intensive care unit of a tertiary care medical institute of Eastern India: A retrospective cross-sectional study&quot;,&quot;attachmentId&quot;:82915789,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/74947735/Bacteriological_profile_and_antibiotic_susceptibility_of_neonatal_sepsis_in_neonatal_intensive_care_unit_of_a_tertiary_care_medical_institute_of_Eastern_India_A_retrospective_cross_sectional_study&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/74947735/Bacteriological_profile_and_antibiotic_susceptibility_of_neonatal_sepsis_in_neonatal_intensive_care_unit_of_a_tertiary_care_medical_institute_of_Eastern_India_A_retrospective_cross_sectional_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:96299742,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--sticky-ctas&quot;,&quot;attachmentId&quot;:96299742,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_96299742" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="38710595" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/38710595/Microbial_profile_of_neonatal_sepsis_and_antibiotic_resistance_from_a_tertiary_care_hospital_in_South_India">Microbial profile of neonatal sepsis and antibiotic resistance from a tertiary care hospital in South India</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="108820338" href="https://independent.academia.edu/KalaivaniR6">Kalaivani R</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="27377481" href="https://innovativepublication.academia.edu/IP">IP Innovative Publication Pvt. 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Ltd., 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Microbial profile of neonatal sepsis and antibiotic resistance from a tertiary care hospital in South India&quot;,&quot;attachmentId&quot;:58794354,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/38710595/Microbial_profile_of_neonatal_sepsis_and_antibiotic_resistance_from_a_tertiary_care_hospital_in_South_India&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/38710595/Microbial_profile_of_neonatal_sepsis_and_antibiotic_resistance_from_a_tertiary_care_hospital_in_South_India"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="1" data-entity-id="48871990" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/48871990/Clinicobacteriological_profile_antibiotic_sensitivity_patterns_and_mortality_of_neonatal_sepsis_in_a_tertiary_care_hospital_in_Kashmir_Jammu_and_Kashmir_India">Clinicobacteriological profile, antibiotic sensitivity patterns and mortality of neonatal sepsis in a tertiary care hospital in Kashmir, Jammu and Kashmir, India</a><div class="ds-related-work--metadata"><a 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