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intake of high-fat diet in critical periods of pregnancy and/or suckling period predisposes nonalcoholic fatty liver disease in adult C57BL/6 mice offspring.","publication_date":"2010,,","publication_name":"American Journal of Obstetrics and Gynecology","grobid_abstract_attachment_id":"44274962"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [33344234,33313530]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" 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data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hepatic structural alteration in adult programmed offspring (severe maternal protein restriction) is aggravated by post-weaning high-fat diet","attachmentId":44179325,"attachmentType":"pdf","work_url":"https://www.academia.edu/14399653/Hepatic_structural_alteration_in_adult_programmed_offspring_severe_maternal_protein_restriction_is_aggravated_by_post_weaning_high_fat_diet","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/14399653/Hepatic_structural_alteration_in_adult_programmed_offspring_severe_maternal_protein_restriction_is_aggravated_by_post_weaning_high_fat_diet"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="14612305" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/14612305/Maternal_obesity_during_pregnancy_and_lactation_programs_the_development_of_offspring_non_alcoholic_fatty_liver_disease_in_mice">Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33774688" href="https://kcl.academia.edu/AnnemajSamuelsson">Anne-maj Samuelsson</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33562675" href="https://independent.academia.edu/SusanOzanne">Susan Ozanne</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Hepatology, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice","attachmentId":44035842,"attachmentType":"pdf","work_url":"https://www.academia.edu/14612305/Maternal_obesity_during_pregnancy_and_lactation_programs_the_development_of_offspring_non_alcoholic_fatty_liver_disease_in_mice","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/14612305/Maternal_obesity_during_pregnancy_and_lactation_programs_the_development_of_offspring_non_alcoholic_fatty_liver_disease_in_mice"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="121420614" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/121420614/Maternal_and_Post_Weaning_Exposure_to_a_High_Fat_Diet_Promotes_Visceral_Obesity_and_Hepatic_Steatosis_in_Adult_Rats">Maternal and Post-Weaning Exposure to a High Fat Diet Promotes Visceral Obesity and Hepatic Steatosis in Adult Rats</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="310267285" href="https://independent.academia.edu/RaulManhaes">Raul Manhaes</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Nutricion hospitalaria, 2015</p><p class="ds-related-work--abstract ds2-5-body-sm">considering the frequent consumption of fatrich diets by women of reproductive age, the aim of the present study was to investigate the effects of maternal consumption of a high-fat diet during the perinatal and/ or post-weaning period on the liver parameters and lipid metabolism of young rats. Wistar female rats were fed a high-fat (H) or control (C) diet during pregnancy and lactation. The offspring were allocated to four groups: Control Control (CC, n = 11), offspring fed a control diet after weaning; Control High-fat (CH, n = 10), offspring fed a high-fat diet after weaning; High-fat High-fat (HH, n = 10), offspring of mothers H fed a high-fat diet after weaning; and High-fat Control (HC, n = 9), offspring of mothers H fed with control diet after weaning. the food intake did not differ among the groups, however, the relative weight of the adipose tissue was higher in animals from the HC, HH and CH groups (p ≤ 0.005). Liver steatosis was found in the CH and HH animals, which also...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Maternal and Post-Weaning Exposure to a High Fat Diet Promotes Visceral Obesity and Hepatic Steatosis in Adult Rats","attachmentId":116300728,"attachmentType":"pdf","work_url":"https://www.academia.edu/121420614/Maternal_and_Post_Weaning_Exposure_to_a_High_Fat_Diet_Promotes_Visceral_Obesity_and_Hepatic_Steatosis_in_Adult_Rats","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/121420614/Maternal_and_Post_Weaning_Exposure_to_a_High_Fat_Diet_Promotes_Visceral_Obesity_and_Hepatic_Steatosis_in_Adult_Rats"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="91790076" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/91790076/A_Slow_Digesting_Carbohydrate_Diet_during_Rat_Pregnancy_Protects_Offspring_from_Non_Alcoholic_Fatty_Liver_Disease_Risk_through_the_Modulation_of_the_Carbohydrate_Response_Element_and_Sterol_Regulatory_Element_Binding_Proteins">A Slow-Digesting Carbohydrate Diet during Rat Pregnancy Protects Offspring from Non-Alcoholic Fatty Liver Disease Risk through the Modulation of the Carbohydrate-Response Element and Sterol Regulatory Element Binding Proteins</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="247596909" href="https://independent.academia.edu/PROFRAMAAZUCENACASTROESTRADA">PROFRA. MA. AZUCENA CASTRO ESTRADA.</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Nutrients, 2019</p><p class="ds-related-work--abstract ds2-5-body-sm">High-fat (HF) and rapid digestive (RD) carbohydrate diets during pregnancy promote excessive adipogenesis in offspring. This effect can be corrected by diets with similar glycemic loads, but low rates of carbohydrate digestion. However, the effects of these diets on metabolic programming in the livers of offspring, and the liver metabolism contributions to adipogenesis, remain to be addressed. In this study, pregnant insulin-resistant rats were fed high-fat diets with similar glycemic loads but different rates of carbohydrate digestion, High Fat-Rapid Digestive (HF–RD) diet or High Fat-Slow Digestive (HF–SD) diet. Offspring were fed a standard diet for 10 weeks, and the impact of these diets on the metabolic and signaling pathways involved in liver fat synthesis and storage of offspring were analyzed, including liver lipidomics, glycogen and carbohydrate and lipid metabolism key enzymes and signaling pathways. Livers from animals whose mothers were fed an HF–RD diet showed higher sa...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A Slow-Digesting Carbohydrate Diet during Rat Pregnancy Protects Offspring from Non-Alcoholic Fatty Liver Disease Risk through the Modulation of the Carbohydrate-Response Element and Sterol Regulatory Element Binding Proteins","attachmentId":94976842,"attachmentType":"pdf","work_url":"https://www.academia.edu/91790076/A_Slow_Digesting_Carbohydrate_Diet_during_Rat_Pregnancy_Protects_Offspring_from_Non_Alcoholic_Fatty_Liver_Disease_Risk_through_the_Modulation_of_the_Carbohydrate_Response_Element_and_Sterol_Regulatory_Element_Binding_Proteins","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/91790076/A_Slow_Digesting_Carbohydrate_Diet_during_Rat_Pregnancy_Protects_Offspring_from_Non_Alcoholic_Fatty_Liver_Disease_Risk_through_the_Modulation_of_the_Carbohydrate_Response_Element_and_Sterol_Regulatory_Element_Binding_Proteins"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="96772546" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/96772546/Maternal_High_Fat_Diet_Programs_Rat_Offspring_Liver_Fatty_Acid_Metabolism">Maternal High-Fat-Diet Programs Rat Offspring Liver Fatty Acid Metabolism</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="206331257" href="https://independent.academia.edu/MichaelRoss141">Michael Ross</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Lipids, 2015</p><p class="ds-related-work--abstract ds2-5-body-sm">In offspring exposed in utero to a maternal diet high in fat (HF), we have previously demonstrated that despite similar birth weights, HF adult offspring at 6 months of age had significantly higher body weights, greater adiposity, and increased triacylglycerol (TAG) levels as compared to controls. We hypothesized that a maternal HF diet predisposes to offspring adiposity via a programmed increase in the synthesis of monounsaturated fatty acids in the liver and hence increased substrate availability for liver TAG synthesis. We further hypothesized that programmed changes in offspring liver fatty acid metabolism are associated with increased liver expression of the lipogenic enzyme stearoyl-CoA desaturase-1 (SCD-1). Female rats were maintained on a HF diet rich in monounsaturated fatty acids (MUFA) prior to and throughout pregnancy and lactation. After birth, newborns were nursed by the same dam, and all offspring were weaned to control diet. Plasma and liver fatty acid compositions w...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Maternal High-Fat-Diet Programs Rat Offspring Liver Fatty Acid Metabolism","attachmentId":98578146,"attachmentType":"pdf","work_url":"https://www.academia.edu/96772546/Maternal_High_Fat_Diet_Programs_Rat_Offspring_Liver_Fatty_Acid_Metabolism","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/96772546/Maternal_High_Fat_Diet_Programs_Rat_Offspring_Liver_Fatty_Acid_Metabolism"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="80543154" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/80543154/Maternal_Dietary_Restriction_and_the_Effects_of_Postweaning_Nutrition_on_Fetal_Development_Insulin_Signalling_Glucose_Metabolism_and_Body_Composition_In_C57BL_6J_Mice">Maternal Dietary Restriction and the Effects of Postweaning Nutrition on Fetal Development, Insulin Signalling, Glucose Metabolism and Body Composition In C57BL/6J Mice</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32867802" href="https://independent.academia.edu/StephenLye">Stephen Lye</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Maternal Dietary Restriction and the Effects of Postweaning Nutrition on Fetal Development, Insulin Signalling, Glucose Metabolism and Body Composition In C57BL/6J Mice","attachmentId":86889807,"attachmentType":"pdf","work_url":"https://www.academia.edu/80543154/Maternal_Dietary_Restriction_and_the_Effects_of_Postweaning_Nutrition_on_Fetal_Development_Insulin_Signalling_Glucose_Metabolism_and_Body_Composition_In_C57BL_6J_Mice","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/80543154/Maternal_Dietary_Restriction_and_the_Effects_of_Postweaning_Nutrition_on_Fetal_Development_Insulin_Signalling_Glucose_Metabolism_and_Body_Composition_In_C57BL_6J_Mice"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="15193128" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/15193128/Early_onset_of_fatty_liver_in_growth_restricted_rat_fetuses_and_newborns">Early onset of fatty liver in growth-restricted rat fetuses and newborns</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="25152791" href="https://independent.academia.edu/MinaDesai">Mina Desai</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="34251626" href="https://independent.academia.edu/WolfeDiana">Diana Wolfe</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Congenital Anomalies, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Early onset of fatty liver in growth-restricted rat fetuses and newborns","attachmentId":43473000,"attachmentType":"pdf","work_url":"https://www.academia.edu/15193128/Early_onset_of_fatty_liver_in_growth_restricted_rat_fetuses_and_newborns","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/15193128/Early_onset_of_fatty_liver_in_growth_restricted_rat_fetuses_and_newborns"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="98531727" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/98531727/Gestational_exercise_protects_adult_male_offspring_from_high_fat_diet_induced_hepatic_steatosis">Gestational exercise protects adult male offspring from high-fat diet-induced hepatic steatosis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="47431027" href="https://independent.academia.edu/RyanSheldon2">Ryan Sheldon</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Hepatology, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Gestational exercise protects adult male offspring from high-fat diet-induced hepatic steatosis","attachmentId":99856229,"attachmentType":"pdf","work_url":"https://www.academia.edu/98531727/Gestational_exercise_protects_adult_male_offspring_from_high_fat_diet_induced_hepatic_steatosis","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/98531727/Gestational_exercise_protects_adult_male_offspring_from_high_fat_diet_induced_hepatic_steatosis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="10271311" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/10271311/Gender_specific_programmed_hepatic_lipid_dysregulation_in_intrauterine_growth_restricted_offspring">Gender-specific programmed hepatic lipid dysregulation in intrauterine growth-restricted offspring</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="25152791" href="https://independent.academia.edu/MinaDesai">Mina Desai</a></div><p class="ds-related-work--metadata ds2-5-body-xs">American Journal of Obstetrics and Gynecology, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Gender-specific programmed hepatic lipid dysregulation in intrauterine growth-restricted offspring","attachmentId":47460859,"attachmentType":"pdf","work_url":"https://www.academia.edu/10271311/Gender_specific_programmed_hepatic_lipid_dysregulation_in_intrauterine_growth_restricted_offspring","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/10271311/Gender_specific_programmed_hepatic_lipid_dysregulation_in_intrauterine_growth_restricted_offspring"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="34488050" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/34488050/The_effect_of_maternal_and_post_weaning_low_and_high_glycaemic_index_diets_on_glucose_tolerance_fat_deposition_and_hepatic_function_in_rat_offspring">The effect of maternal and post-weaning low and high glycaemic index diets on glucose tolerance, fat deposition and hepatic function in rat offspring</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="67958131" href="https://independent.academia.edu/MohammedAlNussairawi">Mohammed Al-Nussairawi</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Clinical studies have reported beneficial effects of a maternal low glycaemic index (GI) diet on pregnancy and neonatal outcomes, but the impact of the diet on the offspring in later life, and the mechanisms underlying these effects, remain unclear. In this study, Albino Wistar rats were fed either a low GI (n = 14) or high GI (n = 14) diet during pregnancy and lactation and their offspring weaned onto either the low or high GI diet. Low GI dams had better glucose tolerance (AUC [glucose], 1322 ± 55 v. 1523 ± 72 mmol min/l, P < 0.05) and a lower proportion of visceral fat (19.0 ± 2.9 v. 21.7 ± 3.8% of total body fat, P < 0.05) compared to high GI dams. Female offspring of low GI dams had lower visceral adiposity (0.45 ± 0.03 v. 0.53 ± 0.03% body weight, P < 0.05) and higher glucose tolerance (AUC [glucose] , 1243 ± 29 v. 1351 ± 39 mmol min/l, P < 0.05) at weaning, as well as lower hepatic PI3K-p85 mRNA at 12 weeks of age. No differences in glucose tolerance or hepatic gene expression were observed in male offspring, but the male low GI offspring did have reduced hepatic lipid content at weaning. These findings suggest that consuming a low GI diet during pregnancy and lactation can improve glucose tolerance and reduce visceral adiposity in the female offspring at weaning, and may potentially produce long-term reductions in the hepatic lipogenic capacity of these offspring.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The effect of maternal and post-weaning low and high glycaemic index diets on glucose tolerance, fat deposition and hepatic function in rat offspring","attachmentId":54356171,"attachmentType":"pdf","work_url":"https://www.academia.edu/34488050/The_effect_of_maternal_and_post_weaning_low_and_high_glycaemic_index_diets_on_glucose_tolerance_fat_deposition_and_hepatic_function_in_rat_offspring","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/34488050/The_effect_of_maternal_and_post_weaning_low_and_high_glycaemic_index_diets_on_glucose_tolerance_fat_deposition_and_hepatic_function_in_rat_offspring"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":44274962,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":44274962,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_44274962" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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Anderson</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Nutrients</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"High Choline Intake during Pregnancy Reduces Characteristics of the Metabolic Syndrome in Male Wistar Rat Offspring Fed a High Fat But Not a Normal Fat Post-Weaning Diet","attachmentId":79829071,"attachmentType":"pdf","work_url":"https://www.academia.edu/69913978/High_Choline_Intake_during_Pregnancy_Reduces_Characteristics_of_the_Metabolic_Syndrome_in_Male_Wistar_Rat_Offspring_Fed_a_High_Fat_But_Not_a_Normal_Fat_Post_Weaning_Diet","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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href="https://ffarmasi.academia.edu/desmawatidesmawati">desmawati desmawati</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Majalah Kedokteran Bandung</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Effect of High Fat Diet on Histopathological Appearance of Pregnant Wistar Rat’s Liver","attachmentId":105254091,"attachmentType":"pdf","work_url":"https://www.academia.edu/105917896/Effect_of_High_Fat_Diet_on_Histopathological_Appearance_of_Pregnant_Wistar_Rat_s_Liver","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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class="ds-related-work--metadata ds2-5-body-xs">Frontiers in Endocrinology, 2022</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Animal Foetal Models of Obesity and Diabetes – From Laboratory to Clinical Settings","attachmentId":84054309,"attachmentType":"pdf","work_url":"https://www.academia.edu/76306935/Animal_Foetal_Models_of_Obesity_and_Diabetes_From_Laboratory_to_Clinical_Settings","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/76306935/Animal_Foetal_Models_of_Obesity_and_Diabetes_From_Laboratory_to_Clinical_Settings"><span class="ds2-5-text-link__content">View 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ds2-5-body-xs">2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Maternal protein restriction during pregnancy and lactation in rats imprints long-term reduction in hepatic lipid content selectively in the male offspring","attachmentId":71461202,"attachmentType":"pdf","work_url":"https://www.academia.edu/55725481/Maternal_protein_restriction_during_pregnancy_and_lactation_in_rats_imprints_long_term_reduction_in_hepatic_lipid_content_selectively_in_the_male_offspring","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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href="https://ohsu.academia.edu/DanielMarks">Daniel Marks</a></div><p class="ds-related-work--metadata ds2-5-body-xs">American Journal of Physiology-Endocrinology and Metabolism, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Increased maternal fat consumption during pregnancy alters body composition in neonatal mice","attachmentId":100014807,"attachmentType":"pdf","work_url":"https://www.academia.edu/98747116/Increased_maternal_fat_consumption_during_pregnancy_alters_body_composition_in_neonatal_mice","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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