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(PDF) The challenge of preventing environmentally related disease in young children: community-based research in New York City | Virginia Rauh, Rachel Miller, Robert Maynard, and Robin Whyatt - Academia.edu

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{"work":{"id":12652599,"created_at":"2015-05-28T08:51:40.502-07:00","from_world_paper_id":136967804,"updated_at":"2021-01-14T16:56:26.104-08:00","_data":{"publication_date":"2002,,"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"The challenge of preventing environmentally related disease in young children: community-based research in New York City","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [45255692,38212826,51020160,31638725]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div 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Based on exposure-response functions from a U.S. cohort study, we assessed the attributable risk of postneonatal infant mortality in 23 U.S. metropolitan areas related to particulate matter &amp;lt;10 microm in diameter (PM10) as a surrogate of total air pollution. The estimated proportion of all cause mortality, sudden infant death syndrome (normal birth weight infants only) and respiratory disease mortality (normal birth weight) attributable to PM10 above a chosen reference value of 12.0 microg/m3 PM10 was 6% (95% confidence interval 3-11%), 16% (95% confidence interval 9-23%) and 24% (95% confidence interval 7-44%), respectively. The expected number of infant deaths per year in the selected areas was 106 (95% confidence interval 53-185), 79 (95% confidence interval 46-111) and 15 (95% confidence interval 5-27), respectively. Approximately 75% of cases were from areas where the current levels are at or be...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Air pollution attributable postneonatal infant mortality in U.S. metropolitan areas: a risk assessment study&quot;,&quot;attachmentId&quot;:40629655,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/19454623/Air_pollution_attributable_postneonatal_infant_mortality_in_U_S_metropolitan_areas_a_risk_assessment_study&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/19454623/Air_pollution_attributable_postneonatal_infant_mortality_in_U_S_metropolitan_areas_a_risk_assessment_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="65310306" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/65310306/The_NYU_Children_s_Health_and_Environment_Study">The NYU Children’s Health and Environment Study</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="44886179" href="https://independent.academia.edu/DorisDescorbeth">Doris Descorbeth</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European Journal of Epidemiology, 2020</p><p class="ds-related-work--abstract ds2-5-body-sm">The aims of the NYU Children’s Health and Environment Study (CHES) are to evaluate influences of prenatal non-persistent chemical exposures on fetal and postnatal growth and pool our data with the US National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) Program to answer collaborative research questions on the impact of the preconceptual, prenatal, and postnatal environment on childhood obesity, neurodevelopment, pre/peri/postnatal outcomes, upper and lower airway outcomes, and positive health. Eligible women were ≥ 18 years old, &lt; 18 weeks pregnant, had a pregnancy that is not medically threatened, and planned to deliver at NYU Langone Hospital—Manhattan, Bellevue Hospital, or NYU Langone Hospital—Brooklyn. Between March 22, 2016 and April 15, 2019, we recruited 2469 pregnant women, from whom 2193 completed an initial questionnaire and continued into NYU CHES. Of the 2193, 88 miscarried, 28 terminated, and 20 experienced stillbirth, while 57 were lost to follow up. We report here demographic and other characteristics of the 2000 live deliveries (2037 children), from whom 1624 (80%) consented to postnatal follow-up. Data collection in pregnancy was nested in clinical care, with questionnaire and specimen collection conducted during routine prenatal visits at &lt; 18, 18–25, and &gt; 25 weeks gestation. 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data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Intrauterine and early postnatal exposure to outdoor air pollution and lung function at preschool age&quot;,&quot;attachmentId&quot;:101701068,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/101056099/Intrauterine_and_early_postnatal_exposure_to_outdoor_air_pollution_and_lung_function_at_preschool_age&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/101056099/Intrauterine_and_early_postnatal_exposure_to_outdoor_air_pollution_and_lung_function_at_preschool_age"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="61807414" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/61807414/The_Mothers_and_Children_s_Environmental_Health_MOCEH_study">The Mothers and Children’s Environmental Health (MOCEH) study</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="34146520" href="https://independent.academia.edu/YanghoKim">Yangho Kim</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European Journal of Epidemiology, 2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;The Mothers and Children’s Environmental Health (MOCEH) study&quot;,&quot;attachmentId&quot;:74750500,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/61807414/The_Mothers_and_Children_s_Environmental_Health_MOCEH_study&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/61807414/The_Mothers_and_Children_s_Environmental_Health_MOCEH_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="26983329" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26983329/Childrens_Environmental_Health_Research_Highlights_from_the_Columbia_Center_for_Childrens_Environmental_Health">Children&#39;s Environmental Health Research--Highlights from the Columbia Center for Children&#39;s Environmental Health</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31638725" href="https://independent.academia.edu/VirginiaRauh">Virginia Rauh</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of the New York Academy of Sciences, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Children&#39;s Environmental Health Research--Highlights from the Columbia Center for Children&#39;s Environmental Health&quot;,&quot;attachmentId&quot;:47245618,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/26983329/Childrens_Environmental_Health_Research_Highlights_from_the_Columbia_Center_for_Childrens_Environmental_Health&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/26983329/Childrens_Environmental_Health_Research_Highlights_from_the_Columbia_Center_for_Childrens_Environmental_Health"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="117567123" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/117567123/Post_birth_exposure_contrasts_for_children_during_the_Household_Air_Pollution_Intervention_Network_randomized_controlled_trial">Post-birth exposure contrasts for children during the Household Air Pollution Intervention Network randomized controlled trial</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="306298253" href="https://independent.academia.edu/FlorienNdagijimana">Florien Ndagijimana</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Exposure to household air pollution is a leading cause of ill-health globally. The Household Air Pollution Intervention Network (HAPIN) randomized controlled trial evaluated the impact of a free liquefied petroleum gas stove and fuel intervention on birth outcomes and maternal and child health. As part of HAPIN, an extensive exposure assessment was conducted. Here, we report on PM2.5and CO exposures of young children (≤ 15 months old) reconstructed using a Bluetooth-beacon based time-activity monitoring system coupled with microenvironmental pollutant monitors. Median (IQR) exposures to PM2.5were 65.1 (33 – 128.2) µg/m3in the control group and 22.9 (17.2 – 35.3) µg/m3 in the intervention group; for CO, median (IQR) exposures were 1.1 (0.3 – 2.9) ppm and 0.2 (0 – 0.7) ppm for control and intervention group, respectively. Exposure reductions were stable over time and consistent with previous findings for the children’s mothers. In the intervention group, 75% of children’s reconstructe...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Post-birth exposure contrasts for children during the Household Air Pollution Intervention Network randomized controlled trial&quot;,&quot;attachmentId&quot;:113390684,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/117567123/Post_birth_exposure_contrasts_for_children_during_the_Household_Air_Pollution_Intervention_Network_randomized_controlled_trial&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/117567123/Post_birth_exposure_contrasts_for_children_during_the_Household_Air_Pollution_Intervention_Network_randomized_controlled_trial"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="92268948" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/92268948/Health_Outcomes_in_Children_Associated_with_Prenatal_and_Early_Life_Exposures_to_Air_Pollution_A_Narrative_Review">Health Outcomes in Children Associated with Prenatal and Early-Life Exposures to Air Pollution: A Narrative Review</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="115333628" href="https://independent.academia.edu/ErikaGarcia249">Erika Garcia</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Toxics</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Health Outcomes in Children Associated with Prenatal and Early-Life Exposures to Air Pollution: A Narrative Review&quot;,&quot;attachmentId&quot;:95322286,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/92268948/Health_Outcomes_in_Children_Associated_with_Prenatal_and_Early_Life_Exposures_to_Air_Pollution_A_Narrative_Review&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/92268948/Health_Outcomes_in_Children_Associated_with_Prenatal_and_Early_Life_Exposures_to_Air_Pollution_A_Narrative_Review"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="115699541" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/115699541/Maternal_Exposure_to_Fine_Particulate_Pollution_During_Narrow_Gestational_Periods_and_Newborn_Health_in_Harris_County_Texas">Maternal Exposure to Fine Particulate Pollution During Narrow Gestational Periods and Newborn Health in Harris County, Texas</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="224187186" href="https://independent.academia.edu/LaiDejian">Dejian Lai</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Maternal and Child Health Journal, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Maternal Exposure to Fine Particulate Pollution During Narrow Gestational Periods and Newborn Health in Harris County, Texas&quot;,&quot;attachmentId&quot;:112033528,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/115699541/Maternal_Exposure_to_Fine_Particulate_Pollution_During_Narrow_Gestational_Periods_and_Newborn_Health_in_Harris_County_Texas&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/115699541/Maternal_Exposure_to_Fine_Particulate_Pollution_During_Narrow_Gestational_Periods_and_Newborn_Health_in_Harris_County_Texas"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:46026782,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" 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