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oxidative stress, or immune function in healthy Australian males</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23886409" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d6a997011814f74e924ad0e9ccfefe03" rel="nofollow" data-download="{"attachment_id":44275640,"asset_id":23886409,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" 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u-positionRelative">27</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6697" href="https://www.academia.edu/Documents/in/Australia">Australia</a>, <script data-card-contents-for-ri="6697" type="text/json">{"id":6697,"name":"Australia","url":"https://www.academia.edu/Documents/in/Australia?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14292" href="https://www.academia.edu/Documents/in/Oxidative_Stress">Oxidative Stress</a>, <script data-card-contents-for-ri="14292" type="text/json">{"id":14292,"name":"Oxidative Stress","url":"https://www.academia.edu/Documents/in/Oxidative_Stress?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14406" href="https://www.academia.edu/Documents/in/Health">Health</a>, <script data-card-contents-for-ri="14406" 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href="https://www.academia.edu/63389422/A_social_ecological_model_of_readiness_for_transition_to_adult_oriented_care_for_adolescents_and_young_adults_with_chronic_health_conditions">A social-ecological model of readiness for transition to adult-oriented care for adolescents and young adults with chronic health conditions</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/63389422" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="50316c72aa556f7e2477f5fadf7e3e07" rel="nofollow" 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data-work_id="13328849" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13328849/Understanding_the_Will_to_Live_in_Patients_Nearing_Death">Understanding the Will to Live in Patients Nearing Death</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13328849" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e81d1eaac8222ca30e2269fd0453f827" rel="nofollow" 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itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13328868/Dignity_in_the_terminally_ill_a_cross_sectional_cohort_study">Dignity in the terminally ill: a cross-sectional, cohort study</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13328868" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9b266fcdddd2f238db3d28e4f54ececc" rel="nofollow" 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data-has-card-for-user="137493591" href="https://independent.academia.edu/PhillipRodgers1">Phillip Rodgers</a><script data-card-contents-for-user="137493591" type="text/json">{"id":137493591,"first_name":"Phillip","last_name":"Rodgers","domain_name":"independent","page_name":"PhillipRodgers1","display_name":"Phillip Rodgers","profile_url":"https://independent.academia.edu/PhillipRodgers1?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_77555129 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="77555129"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 77555129, container: ".js-paper-rank-work_77555129", }); });</script></li><li class="js-percentile-work_77555129 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget 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href="https://www.academia.edu/Documents/in/Palliative_Care">Palliative Care</a>, <script data-card-contents-for-ri="4482" type="text/json">{"id":4482,"name":"Palliative Care","url":"https://www.academia.edu/Documents/in/Palliative_Care?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="40165" href="https://www.academia.edu/Documents/in/Pain_Management">Pain Management</a><script data-card-contents-for-ri="40165" type="text/json">{"id":40165,"name":"Pain Management","url":"https://www.academia.edu/Documents/in/Pain_Management?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new 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itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15955864/Molecular_imaging_of_hypoxia_with_radiolabelled_agents">Molecular imaging of hypoxia with radiolabelled agents</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Tissue hypoxia results from an inadequate supply of oxygen (O2) that compromises biological functions. Structural and functional abnormalities of the tumour vasculature together with altered diffusion conditions inside the tumour seem to... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_15955864" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Tissue hypoxia results from an inadequate supply of oxygen (O2) that compromises biological functions. Structural and functional abnormalities of the tumour vasculature together with altered diffusion conditions inside the tumour seem to be the main causes of tumour hypoxia. Evidence from experimental and clinical studies points to a role for tumour hypoxia in tumour propagation, resistance to therapy and malignant</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15955864" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="744abeb60d0047c4d7783e55a5be5154" rel="nofollow" data-download="{"attachment_id":42814315,"asset_id":15955864,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42814315/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35111225" href="https://independent.academia.edu/ChristelVangestel">Christel Vangestel</a><script data-card-contents-for-user="35111225" type="text/json">{"id":35111225,"first_name":"Christel","last_name":"Vangestel","domain_name":"independent","page_name":"ChristelVangestel","display_name":"Christel Vangestel","profile_url":"https://independent.academia.edu/ChristelVangestel?f_ri=469018","photo":"https://0.academia-photos.com/35111225/10210169/11394063/s65_christel.vangestel.jpg"}</script></span></span></li><li class="js-paper-rank-work_15955864 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15955864"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15955864, container: ".js-paper-rank-work_15955864", }); 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type="text/json">{"id":923,"name":"Technology","url":"https://www.academia.edu/Documents/in/Technology?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a>, <script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62710" href="https://www.academia.edu/Documents/in/Tumor_microenvironment">Tumor microenvironment</a>, <script data-card-contents-for-ri="62710" type="text/json">{"id":62710,"name":"Tumor microenvironment","url":"https://www.academia.edu/Documents/in/Tumor_microenvironment?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a><script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=21145535]'), work: {"id":21145535,"title":"Exosome in Tumour Microenvironment: Overview of the Crosstalk between Normal and Cancer Cells","created_at":"2016-01-29T07:48:46.463-08:00","url":"https://www.academia.edu/21145535/Exosome_in_Tumour_Microenvironment_Overview_of_the_Crosstalk_between_Normal_and_Cancer_Cells?f_ri=469018","dom_id":"work_21145535","summary":null,"downloadable_attachments":[{"id":41735413,"asset_id":21145535,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5795824,"first_name":"Pedro","last_name":"Baptista","domain_name":"unl-pt","page_name":"PedroBaptista","display_name":"Pedro Baptista","profile_url":"https://unl-pt.academia.edu/PedroBaptista?f_ri=469018","photo":"https://0.academia-photos.com/5795824/10502408/18506425/s65_pedro.baptista.jpg"}],"research_interests":[{"id":923,"name":"Technology","url":"https://www.academia.edu/Documents/in/Technology?f_ri=469018","nofollow":false},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=469018","nofollow":false},{"id":62710,"name":"Tumor microenvironment","url":"https://www.academia.edu/Documents/in/Tumor_microenvironment?f_ri=469018","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018","nofollow":false},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals?f_ri=469018"},{"id":165131,"name":"Exosomes","url":"https://www.academia.edu/Documents/in/Exosomes?f_ri=469018"},{"id":222543,"name":"Biomed","url":"https://www.academia.edu/Documents/in/Biomed?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"},{"id":846581,"name":"Cell communication","url":"https://www.academia.edu/Documents/in/Cell_communication?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_78250881" data-work_id="78250881" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/78250881/Membrane_Type_1_Matrix_Metalloproteinase_associated_Degradation_of_Tissue_Inhibitor_of_Metalloproteinase_2_in_Human_Tumor_Cell_Lines">Membrane Type 1 Matrix Metalloproteinase-associated Degradation of Tissue Inhibitor of Metalloproteinase 2 in Human Tumor Cell Lines</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/78250881" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8cbfc902047d9640ba8f2cc26e98a10a" rel="nofollow" data-download="{"attachment_id":85362934,"asset_id":78250881,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/85362934/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="222467013" href="https://independent.academia.edu/RemacleAlbert">Albert Remacle</a><script data-card-contents-for-user="222467013" type="text/json">{"id":222467013,"first_name":"Albert","last_name":"Remacle","domain_name":"independent","page_name":"RemacleAlbert","display_name":"Albert Remacle","profile_url":"https://independent.academia.edu/RemacleAlbert?f_ri=469018","photo":"https://0.academia-photos.com/222467013/80073093/68647308/s65_albert.remacle.png"}</script></span></span></li><li class="js-paper-rank-work_78250881 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="78250881"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 78250881, container: ".js-paper-rank-work_78250881", }); });</script></li><li class="js-percentile-work_78250881 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 78250881; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_78250881"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_78250881 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="78250881"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 78250881; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=78250881]").text(description); $(".js-view-count-work_78250881").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_78250881").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="78250881"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="523" href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a>, <script data-card-contents-for-ri="523" type="text/json">{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="11298" href="https://www.academia.edu/Documents/in/Membrane_Proteins">Membrane Proteins</a>, <script data-card-contents-for-ri="11298" type="text/json">{"id":11298,"name":"Membrane Proteins","url":"https://www.academia.edu/Documents/in/Membrane_Proteins?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="18520" href="https://www.academia.edu/Documents/in/Biological_Chemistry">Biological Chemistry</a>, <script data-card-contents-for-ri="18520" type="text/json">{"id":18520,"name":"Biological Chemistry","url":"https://www.academia.edu/Documents/in/Biological_Chemistry?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=78250881]'), work: {"id":78250881,"title":"Membrane Type 1 Matrix Metalloproteinase-associated Degradation of Tissue Inhibitor of Metalloproteinase 2 in Human Tumor Cell Lines","created_at":"2022-05-02T11:49:13.059-07:00","url":"https://www.academia.edu/78250881/Membrane_Type_1_Matrix_Metalloproteinase_associated_Degradation_of_Tissue_Inhibitor_of_Metalloproteinase_2_in_Human_Tumor_Cell_Lines?f_ri=469018","dom_id":"work_78250881","summary":null,"downloadable_attachments":[{"id":85362934,"asset_id":78250881,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":222467013,"first_name":"Albert","last_name":"Remacle","domain_name":"independent","page_name":"RemacleAlbert","display_name":"Albert Remacle","profile_url":"https://independent.academia.edu/RemacleAlbert?f_ri=469018","photo":"https://0.academia-photos.com/222467013/80073093/68647308/s65_albert.remacle.png"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=469018","nofollow":false},{"id":11298,"name":"Membrane Proteins","url":"https://www.academia.edu/Documents/in/Membrane_Proteins?f_ri=469018","nofollow":false},{"id":18520,"name":"Biological Chemistry","url":"https://www.academia.edu/Documents/in/Biological_Chemistry?f_ri=469018","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=469018","nofollow":false},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=469018"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018"},{"id":117643,"name":"Biological","url":"https://www.academia.edu/Documents/in/Biological?f_ri=469018"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES?f_ri=469018"},{"id":382339,"name":"Phenylalanine","url":"https://www.academia.edu/Documents/in/Phenylalanine?f_ri=469018"},{"id":404745,"name":"Protease Inhibitors","url":"https://www.academia.edu/Documents/in/Protease_Inhibitors?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"},{"id":990417,"name":"Recombinant Proteins","url":"https://www.academia.edu/Documents/in/Recombinant_Proteins?f_ri=469018"},{"id":1137254,"name":"Hydrogen-Ion Concentration","url":"https://www.academia.edu/Documents/in/Hydrogen-Ion_Concentration?f_ri=469018"},{"id":1920779,"name":"Matrix Metalloproteinase","url":"https://www.academia.edu/Documents/in/Matrix_Metalloproteinase?f_ri=469018"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_78118425" data-work_id="78118425" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/78118425/Planning_cancer_control_in_Latin_America_and_the_Caribbean">Planning cancer control in Latin America and the Caribbean</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/78118425" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="94f709ed33af3fd7bdbf8c703d148acd" rel="nofollow" data-download="{"attachment_id":85277864,"asset_id":78118425,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/85277864/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="48585206" href="https://independent.academia.edu/RGab%C3%BAs">Raúl Gabús</a><script data-card-contents-for-user="48585206" type="text/json">{"id":48585206,"first_name":"Raúl","last_name":"Gabús","domain_name":"independent","page_name":"RGabús","display_name":"Raúl Gabús","profile_url":"https://independent.academia.edu/RGab%C3%BAs?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_78118425 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="78118425"><i class="u-m1x fa fa-bar-chart"></i><strong 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data-work-id="78118425"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 78118425; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=78118425]").text(description); $(".js-view-count-work_78118425").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_78118425").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="78118425"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4990" href="https://www.academia.edu/Documents/in/Global_Health">Global Health</a>, <script data-card-contents-for-ri="4990" type="text/json">{"id":4990,"name":"Global Health","url":"https://www.academia.edu/Documents/in/Global_Health?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7583" href="https://www.academia.edu/Documents/in/Health_Planning">Health Planning</a>, <script data-card-contents-for-ri="7583" type="text/json">{"id":7583,"name":"Health Planning","url":"https://www.academia.edu/Documents/in/Health_Planning?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="9745" href="https://www.academia.edu/Documents/in/Quality_Improvement">Quality Improvement</a>, <script data-card-contents-for-ri="9745" type="text/json">{"id":9745,"name":"Quality Improvement","url":"https://www.academia.edu/Documents/in/Quality_Improvement?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16749" href="https://www.academia.edu/Documents/in/Cancer_Control">Cancer Control</a><script data-card-contents-for-ri="16749" type="text/json">{"id":16749,"name":"Cancer Control","url":"https://www.academia.edu/Documents/in/Cancer_Control?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=78118425]'), work: {"id":78118425,"title":"Planning cancer control in Latin America and the Caribbean","created_at":"2022-05-01T05:47:46.355-07:00","url":"https://www.academia.edu/78118425/Planning_cancer_control_in_Latin_America_and_the_Caribbean?f_ri=469018","dom_id":"work_78118425","summary":null,"downloadable_attachments":[{"id":85277864,"asset_id":78118425,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":48585206,"first_name":"Raúl","last_name":"Gabús","domain_name":"independent","page_name":"RGabús","display_name":"Raúl Gabús","profile_url":"https://independent.academia.edu/RGab%C3%BAs?f_ri=469018","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4990,"name":"Global Health","url":"https://www.academia.edu/Documents/in/Global_Health?f_ri=469018","nofollow":false},{"id":7583,"name":"Health Planning","url":"https://www.academia.edu/Documents/in/Health_Planning?f_ri=469018","nofollow":false},{"id":9745,"name":"Quality Improvement","url":"https://www.academia.edu/Documents/in/Quality_Improvement?f_ri=469018","nofollow":false},{"id":16749,"name":"Cancer Control","url":"https://www.academia.edu/Documents/in/Cancer_Control?f_ri=469018","nofollow":false},{"id":22255,"name":"Cancer Research","url":"https://www.academia.edu/Documents/in/Cancer_Research?f_ri=469018"},{"id":22733,"name":"Global Health Policy","url":"https://www.academia.edu/Documents/in/Global_Health_Policy?f_ri=469018"},{"id":38657,"name":"Global Cancer Public Health \u0026 Policy","url":"https://www.academia.edu/Documents/in/Global_Cancer_Public_Health_and_Policy?f_ri=469018"},{"id":56989,"name":"Latin America","url":"https://www.academia.edu/Documents/in/Latin_America?f_ri=469018"},{"id":58626,"name":"Health Care reform","url":"https://www.academia.edu/Documents/in/Health_Care_reform?f_ri=469018"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"},{"id":806065,"name":"West Indies","url":"https://www.academia.edu/Documents/in/West_Indies?f_ri=469018"},{"id":4109113,"name":"Latin Americans","url":"https://www.academia.edu/Documents/in/Latin_Americans?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_73022265" data-work_id="73022265" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/73022265/Adipose_Derived_Stems_Cells_and_Their_Role_in_Human_Cancer_Development_Growth_Progression_and_Metastasis_A_Systematic_Review">Adipose-Derived Stems Cells and Their Role in Human Cancer Development, Growth, Progression, and Metastasis: A Systematic Review</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Obesity is a well recognized risk factor for several types of cancers, many of which occur solely or disproportionately in women. Adipose tissue is a rich source of adipose-derived stem cells (ASC), which have received attention for their... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_73022265" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Obesity is a well recognized risk factor for several types of cancers, many of which occur solely or disproportionately in women. Adipose tissue is a rich source of adipose-derived stem cells (ASC), which have received attention for their role in cancer behavior. The purpose of this systematic review is to present the existing literature on the role of ASCs in the growth, development, progression, and metastasis of cancer, with an emphasis on malignancies that primarily affect women. To accomplish this goal, the bibliographic database PubMed was systematically searched for articles published between 2001 and 2014 that address ASCs&#39; relationship to human cancer. Thirty-seven articles on ASCs&#39; role in human cancer were reviewed. Literature suggests that ASCs exhibit cancer-promoting properties, influence/are influenced by the tumor microenvironment, promote angiogenesis, and may be associated with pathogenic processes through a variety of mechanisms, such as playing a role in ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/73022265" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9db2c605d1ab87b5850445b1e4ee76ae" rel="nofollow" data-download="{"attachment_id":81709713,"asset_id":73022265,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81709713/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="48348077" href="https://independent.academia.edu/BrianPhilips1">Brian Philips</a><script data-card-contents-for-user="48348077" type="text/json">{"id":48348077,"first_name":"Brian","last_name":"Philips","domain_name":"independent","page_name":"BrianPhilips1","display_name":"Brian Philips","profile_url":"https://independent.academia.edu/BrianPhilips1?f_ri=469018","photo":"https://0.academia-photos.com/48348077/46399275/35866981/s65_brian.philips.jpg"}</script></span></span></li><li class="js-paper-rank-work_73022265 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="73022265"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 73022265, container: ".js-paper-rank-work_73022265", }); 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$(".js-view-count[data-work-id=73022265]").text(description); $(".js-view-count-work_73022265").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_73022265").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="73022265"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6021" href="https://www.academia.edu/Documents/in/Cancer">Cancer</a>, <script data-card-contents-for-ri="6021" type="text/json">{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="18608" href="https://www.academia.edu/Documents/in/Adult_Stem_Cells">Adult Stem Cells</a>, <script data-card-contents-for-ri="18608" type="text/json">{"id":18608,"name":"Adult Stem Cells","url":"https://www.academia.edu/Documents/in/Adult_Stem_Cells?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62710" href="https://www.academia.edu/Documents/in/Tumor_microenvironment">Tumor microenvironment</a><script data-card-contents-for-ri="62710" type="text/json">{"id":62710,"name":"Tumor microenvironment","url":"https://www.academia.edu/Documents/in/Tumor_microenvironment?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=73022265]'), work: {"id":73022265,"title":"Adipose-Derived Stems Cells and Their Role in Human Cancer Development, Growth, Progression, and Metastasis: A Systematic Review","created_at":"2022-03-04T04:56:17.664-08:00","url":"https://www.academia.edu/73022265/Adipose_Derived_Stems_Cells_and_Their_Role_in_Human_Cancer_Development_Growth_Progression_and_Metastasis_A_Systematic_Review?f_ri=469018","dom_id":"work_73022265","summary":"Obesity is a well recognized risk factor for several types of cancers, many of which occur solely or disproportionately in women. Adipose tissue is a rich source of adipose-derived stem cells (ASC), which have received attention for their role in cancer behavior. The purpose of this systematic review is to present the existing literature on the role of ASCs in the growth, development, progression, and metastasis of cancer, with an emphasis on malignancies that primarily affect women. To accomplish this goal, the bibliographic database PubMed was systematically searched for articles published between 2001 and 2014 that address ASCs\u0026#39; relationship to human cancer. Thirty-seven articles on ASCs\u0026#39; role in human cancer were reviewed. Literature suggests that ASCs exhibit cancer-promoting properties, influence/are influenced by the tumor microenvironment, promote angiogenesis, and may be associated with pathogenic processes through a variety of mechanisms, such as playing a role in ...","downloadable_attachments":[{"id":81709713,"asset_id":73022265,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":48348077,"first_name":"Brian","last_name":"Philips","domain_name":"independent","page_name":"BrianPhilips1","display_name":"Brian Philips","profile_url":"https://independent.academia.edu/BrianPhilips1?f_ri=469018","photo":"https://0.academia-photos.com/48348077/46399275/35866981/s65_brian.philips.jpg"}],"research_interests":[{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=469018","nofollow":false},{"id":18608,"name":"Adult Stem Cells","url":"https://www.academia.edu/Documents/in/Adult_Stem_Cells?f_ri=469018","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=469018","nofollow":false},{"id":62710,"name":"Tumor microenvironment","url":"https://www.academia.edu/Documents/in/Tumor_microenvironment?f_ri=469018","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018"},{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals?f_ri=469018"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=469018"},{"id":340262,"name":"Carcinogenesis","url":"https://www.academia.edu/Documents/in/Carcinogenesis?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=469018"},{"id":2845694,"name":"Adiposity","url":"https://www.academia.edu/Documents/in/Adiposity?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_70393820 coauthored" data-work_id="70393820" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/70393820/Tracheal_stenosis_diagnostic_and_therapeutic_principles_results">Tracheal stenosis--diagnostic and therapeutic principles, results</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Between November 2001-April 2010, 107 tracheal resections were performed in our department for different types of tracheal stenosis: iatrogenic or tumoral, benign or malignant. We present the diagnosis and treatment principles that we... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_70393820" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Between November 2001-April 2010, 107 tracheal resections were performed in our department for different types of tracheal stenosis: iatrogenic or tumoral, benign or malignant. We present the diagnosis and treatment principles that we used, along with our results. We operated on 74 (69.15%) iatrogenic postintubation tracheal stenosis, 6 (5.6%) of them complicated with tracheo-esophageal fistula, 6 (5.6%) benign tumors, 11 (10.28%) primary malignant and 16 (14.97%) secondary malignant ones, with a 3.8% total mortality. Tracheal resection and reconstruction is the only curative treatment for all types of tracheal stenosis. Interventional endoscopy is of a major importance in the assessment and treatment of tracheal stenosis. We believe that each patient diagnosed with a tracheal stenosis should be referred to a tertiary center with multidisciplinary experience in the treatment of tracheal stenosis.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/70393820" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c23b71a9a82db2e3f62fb9140896f95f" rel="nofollow" data-download="{"attachment_id":80239289,"asset_id":70393820,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80239289/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="47549460" href="https://independent.academia.edu/GCadar">Genoveva Cadar</a><script data-card-contents-for-user="47549460" type="text/json">{"id":47549460,"first_name":"Genoveva","last_name":"Cadar","domain_name":"independent","page_name":"GCadar","display_name":"Genoveva Cadar","profile_url":"https://independent.academia.edu/GCadar?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-70393820">+1</span><div class="hidden js-additional-users-70393820"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/CodinSaon">Codin Saon</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-70393820'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-70393820').html(); 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We present the diagnosis and treatment principles that we used, along with our results. We operated on 74 (69.15%) iatrogenic postintubation tracheal stenosis, 6 (5.6%) of them complicated with tracheo-esophageal fistula, 6 (5.6%) benign tumors, 11 (10.28%) primary malignant and 16 (14.97%) secondary malignant ones, with a 3.8% total mortality. Tracheal resection and reconstruction is the only curative treatment for all types of tracheal stenosis. Interventional endoscopy is of a major importance in the assessment and treatment of tracheal stenosis. We believe that each patient diagnosed with a tracheal stenosis should be referred to a tertiary center with multidisciplinary experience in the treatment of tracheal stenosis.","downloadable_attachments":[{"id":80239289,"asset_id":70393820,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":47549460,"first_name":"Genoveva","last_name":"Cadar","domain_name":"independent","page_name":"GCadar","display_name":"Genoveva Cadar","profile_url":"https://independent.academia.edu/GCadar?f_ri=469018","photo":"/images/s65_no_pic.png"},{"id":215920779,"first_name":"Codin","last_name":"Saon","domain_name":"independent","page_name":"CodinSaon","display_name":"Codin Saon","profile_url":"https://independent.academia.edu/CodinSaon?f_ri=469018","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=469018","nofollow":false},{"id":16664,"name":"Risk 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Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=469018"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=469018"},{"id":587542,"name":"Tracheostomy","url":"https://www.academia.edu/Documents/in/Tracheostomy?f_ri=469018"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=469018"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=469018"},{"id":709529,"name":"Tracheal stenosis","url":"https://www.academia.edu/Documents/in/Tracheal_stenosis?f_ri=469018"},{"id":1137021,"name":"Pneumologia","url":"https://www.academia.edu/Documents/in/Pneumologia?f_ri=469018"}]}, }) } 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type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="289271" href="https://www.academia.edu/Documents/in/Aged">Aged</a><script data-card-contents-for-ri="289271" type="text/json">{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=63086476]'), work: {"id":63086476,"title":"Review of current best practice and priorities for research in radiation oncology for elderly patients with cancer: the International Society of Geriatric Oncology (SIOG) task 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Therapy","url":"https://www.academia.edu/Documents/in/Combined_Modality_Therapy?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_62447199" data-work_id="62447199" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/62447199/Exosomes_The_Messengers_of_Health_and_Disease">Exosomes: The Messengers of Health and Disease</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/62447199" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span 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class="u-tcGrayDark u-fw700" data-has-card-for-user="41614163" href="https://independent.academia.edu/ChenSuzie">Suzie Chen</a><script data-card-contents-for-user="41614163" type="text/json">{"id":41614163,"first_name":"Suzie","last_name":"Chen","domain_name":"independent","page_name":"ChenSuzie","display_name":"Suzie Chen","profile_url":"https://independent.academia.edu/ChenSuzie?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_62447199 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="62447199"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 62447199, container: ".js-paper-rank-work_62447199", }); });</script></li><li class="js-percentile-work_62447199 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span 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$(".js-view-count[data-work-id=62447199]").text(description); $(".js-view-count-work_62447199").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_62447199").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="62447199"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a>, <script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="99234" href="https://www.academia.edu/Documents/in/Animals">Animals</a>, <script data-card-contents-for-ri="99234" type="text/json">{"id":99234,"name":"Animals","url":"https://www.academia.edu/Documents/in/Animals?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="165131" href="https://www.academia.edu/Documents/in/Exosomes">Exosomes</a>, <script data-card-contents-for-ri="165131" type="text/json">{"id":165131,"name":"Exosomes","url":"https://www.academia.edu/Documents/in/Exosomes?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="218105" href="https://www.academia.edu/Documents/in/Organelle_biogenesis">Organelle biogenesis</a><script data-card-contents-for-ri="218105" type="text/json">{"id":218105,"name":"Organelle biogenesis","url":"https://www.academia.edu/Documents/in/Organelle_biogenesis?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=62447199]'), work: {"id":62447199,"title":"Exosomes: The Messengers of Health and Disease","created_at":"2021-11-26T03:10:33.249-08:00","url":"https://www.academia.edu/62447199/Exosomes_The_Messengers_of_Health_and_Disease?f_ri=469018","dom_id":"work_62447199","summary":null,"downloadable_attachments":[{"id":75208902,"asset_id":62447199,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41614163,"first_name":"Suzie","last_name":"Chen","domain_name":"independent","page_name":"ChenSuzie","display_name":"Suzie 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communication","url":"https://www.academia.edu/Documents/in/Cell_communication?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_57774635" data-work_id="57774635" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/57774635/Role_of_the_nurse_in_patient_education_and_follow_up_of_people_receiving_oral_chemotherapy_treatment_an_International_survey">Role of the nurse in patient education and follow-up of people receiving oral chemotherapy treatment: an International survey</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm 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class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="164436617" href="https://edithcowan.academia.edu/DavinaPorock">Davina Porock</a><script data-card-contents-for-user="164436617" type="text/json">{"id":164436617,"first_name":"Davina","last_name":"Porock","domain_name":"edithcowan","page_name":"DavinaPorock","display_name":"Davina Porock","profile_url":"https://edithcowan.academia.edu/DavinaPorock?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_57774635 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="57774635"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 57774635, container: 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window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=57774635]").text(description); $(".js-view-count-work_57774635").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_57774635").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="57774635"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="10966" href="https://www.academia.edu/Documents/in/Turkey">Turkey</a>, <script data-card-contents-for-ri="10966" type="text/json">{"id":10966,"name":"Turkey","url":"https://www.academia.edu/Documents/in/Turkey?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12054" href="https://www.academia.edu/Documents/in/International_Cooperation">International Cooperation</a>, <script data-card-contents-for-ri="12054" type="text/json">{"id":12054,"name":"International Cooperation","url":"https://www.academia.edu/Documents/in/International_Cooperation?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="18174" href="https://www.academia.edu/Documents/in/Language">Language</a>, <script data-card-contents-for-ri="18174" type="text/json">{"id":18174,"name":"Language","url":"https://www.academia.edu/Documents/in/Language?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="52710" href="https://www.academia.edu/Documents/in/Patient_education">Patient education</a><script data-card-contents-for-ri="52710" type="text/json">{"id":52710,"name":"Patient education","url":"https://www.academia.edu/Documents/in/Patient_education?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=57774635]'), work: {"id":57774635,"title":"Role of the nurse in patient education and follow-up of people receiving oral chemotherapy treatment: an International 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Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_52853586" data-work_id="52853586" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/52853586/European_Code_against_Cancer_4th_Edition_Cancer_screening">European Code against Cancer, 4th Edition: Cancer screening</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In order to update the previous version of the European Code against Cancer and formulate evidence-based recommendations, a systematic search of the literature was performed according to the methodology agreed by the Code Working Groups.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_52853586" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In order to update the previous version of the European Code against Cancer and formulate evidence-based recommendations, a systematic search of the literature was performed according to the methodology agreed by the Code Working Groups. Based on the review, the 4th edition of the European Code against Cancer recommends: &quot;Take part in organized cancer screening programmes for: Organized screening programs are preferable because they provide better conditions to ensure that the Guidelines for Quality Assurance in Screening are followed in order to achieve the greatest benefit with the least harm. Screening is recommended only for those cancers where a demonstrated life-saving effect substantially outweighs the potential harm of examining very large numbers of people who may otherwise never have, or suffer from, these cancers, and when an adequate quality of the screening is achieved. 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EU citizens are recommended to participate in cancer screening each time an invitation from the ...","downloadable_attachments":[{"id":69916926,"asset_id":52853586,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37571052,"first_name":"J.","last_name":"Regula","domain_name":"independent","page_name":"Regula","display_name":"J. 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Of several radiobiological models, the linear-quadratic (LQ) model has been best validated by experimental and clinical data. Clinically, the LQ model is mainly... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_51979905" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Prediction of radiobiological response is a major challenge in radiotherapy. Of several radiobiological models, the linear-quadratic (LQ) model has been best validated by experimental and clinical data. Clinically, the LQ model is mainly used to estimate equivalent radiotherapy schedules (e.g. calculate the equivalent dose in 2 Gy fractions, EQD), but increasingly also to predict tumour control probability (TCP) and normal tissue complication probability (NTCP) using logistic models. The selection of accurate LQ parameters α, β and α/β is pivotal for a reliable estimate of radiation response. The aim of this review is to provide an overview of published values for the LQ parameters of human tumours as a guideline for radiation oncologists and radiation researchers to select appropriate radiobiological parameter values for LQ modelling in clinical radiotherapy. We performed a systematic literature search and found sixty-four clinical studies reporting α, β and α/β for tumours. Tumour...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51979905" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1831014c5fb537837b816b7c27dae55c" rel="nofollow" data-download="{"attachment_id":69457268,"asset_id":51979905,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69457268/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34169810" href="https://uva.academia.edu/JCrezee">J. 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Of several radiobiological models, the linear-quadratic (LQ) model has been best validated by experimental and clinical data. Clinically, the LQ model is mainly used to estimate equivalent radiotherapy schedules (e.g. calculate the equivalent dose in 2 Gy fractions, EQD), but increasingly also to predict tumour control probability (TCP) and normal tissue complication probability (NTCP) using logistic models. The selection of accurate LQ parameters α, β and α/β is pivotal for a reliable estimate of radiation response. The aim of this review is to provide an overview of published values for the LQ parameters of human tumours as a guideline for radiation oncologists and radiation researchers to select appropriate radiobiological parameter values for LQ modelling in clinical radiotherapy. We performed a systematic literature search and found sixty-four clinical studies reporting α, β and α/β for tumours. 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u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/51532255/Dose_Response_Nonlinearities_for_Benzene_Revisited_A_Reply_to_Crump_et_al_1">Dose-Response Nonlinearities for Benzene Revisited: A Reply to Crump et al.1</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51532255" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="17d6037038fed3606c412073081d76cb" rel="nofollow" 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class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/2641177/A_nationwide_cohort_study_of_educational_background_and_major_causes_of_death_among_the_elderly_population_in_Japan">A nationwide cohort study of educational background and major causes of death among the elderly population in Japan</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This prospective cohort study examined the association between educational level and major causes of death in Japan.A baseline survey was conducted between 1988 and 1990 among 110,792 inhabitants of 45 areas aged 40–79 years. Follow-up... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_2641177" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This prospective cohort study examined the association between educational level and major causes of death in Japan.A baseline survey was conducted between 1988 and 1990 among 110,792 inhabitants of 45 areas aged 40–79 years. Follow-up surveys were conducted annually and causes of death were identified from death certificates. The analysis was restricted to 16,715 men and 23,284 women.During the follow-up period (377,139 person-years), 6628 deaths were recorded. Individuals with low levels of education had an increased overall risk of death [relative risk (RR) = 1.16, 95% confidence interval (CI): 1.08, 1.25, in men; RR = 1.26, 95% CI: 1.14, 1.39, in women], cancers (RR = 1.17, 95% CI: 1.04, 1.32, in men; RR = 1.10, 95% CI: 0.93, 1.30, in women), and death from external causes (RR = 1.81, 95% CI: 1.29. 2.54, in men; RR = 1.78, 95% CI: 1.18, 2.70, in women). Ischemic heart disease risk was marginally reduced in men with low levels of education (RR = 0.77, 95% CI: 0.58, 1.01).These results show that health inequalities exist in Japan, even though wealth inequalities are relatively low. Social and political initiatives will be needed to correct these inequities between different socioeconomic statuses.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/2641177" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f9818fdbd7eb2b20f67d7e03c51647c6" rel="nofollow" data-download="{"attachment_id":50555297,"asset_id":2641177,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50555297/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3363999" href="https://uoeh-u.academia.edu/YoshihisaFujino">Yoshihisa Fujino</a><script data-card-contents-for-user="3363999" type="text/json">{"id":3363999,"first_name":"Yoshihisa","last_name":"Fujino","domain_name":"uoeh-u","page_name":"YoshihisaFujino","display_name":"Yoshihisa Fujino","profile_url":"https://uoeh-u.academia.edu/YoshihisaFujino?f_ri=469018","photo":"https://0.academia-photos.com/3363999/1130151/1416385/s65_yoshihisa.fujino.jpg"}</script></span></span></li><li class="js-paper-rank-work_2641177 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="2641177"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 2641177, container: ".js-paper-rank-work_2641177", }); 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$(".js-view-count[data-work-id=2641177]").text(description); $(".js-view-count-work_2641177").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_2641177").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="2641177"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">27</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6021" href="https://www.academia.edu/Documents/in/Cancer">Cancer</a>, <script data-card-contents-for-ri="6021" type="text/json">{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="13084" href="https://www.academia.edu/Documents/in/Preventive_medicine">Preventive medicine</a>, <script data-card-contents-for-ri="13084" type="text/json">{"id":13084,"name":"Preventive medicine","url":"https://www.academia.edu/Documents/in/Preventive_medicine?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="13734" href="https://www.academia.edu/Documents/in/Communicable_Diseases">Communicable Diseases</a>, <script data-card-contents-for-ri="13734" type="text/json">{"id":13734,"name":"Communicable Diseases","url":"https://www.academia.edu/Documents/in/Communicable_Diseases?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17158" href="https://www.academia.edu/Documents/in/Japan">Japan</a><script data-card-contents-for-ri="17158" type="text/json">{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=2641177]'), work: {"id":2641177,"title":"A nationwide cohort study of educational background and major causes of death among the elderly population in Japan","created_at":"2013-02-24T13:07:11.984-08:00","url":"https://www.academia.edu/2641177/A_nationwide_cohort_study_of_educational_background_and_major_causes_of_death_among_the_elderly_population_in_Japan?f_ri=469018","dom_id":"work_2641177","summary":"This prospective cohort study examined the association between educational level and major causes of death in Japan.A baseline survey was conducted between 1988 and 1990 among 110,792 inhabitants of 45 areas aged 40–79 years. Follow-up surveys were conducted annually and causes of death were identified from death certificates. The analysis was restricted to 16,715 men and 23,284 women.During the follow-up period (377,139 person-years), 6628 deaths were recorded. Individuals with low levels of education had an increased overall risk of death [relative risk (RR) = 1.16, 95% confidence interval (CI): 1.08, 1.25, in men; RR = 1.26, 95% CI: 1.14, 1.39, in women], cancers (RR = 1.17, 95% CI: 1.04, 1.32, in men; RR = 1.10, 95% CI: 0.93, 1.30, in women), and death from external causes (RR = 1.81, 95% CI: 1.29. 2.54, in men; RR = 1.78, 95% CI: 1.18, 2.70, in women). Ischemic heart disease risk was marginally reduced in men with low levels of education (RR = 0.77, 95% CI: 0.58, 1.01).These results show that health inequalities exist in Japan, even though wealth inequalities are relatively low. 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href="https://www.academia.edu/28469457/Interactions_of_Antitumor_Metallodrugs_with_Serum_Proteins_Advances_in_Characterization_Using_Modern_Analytical_Methodology">Interactions of Antitumor Metallodrugs with Serum Proteins: Advances in Characterization Using Modern Analytical Methodology</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28469457" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="224a664e464052749646b0f4c93c7e17" rel="nofollow" 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href="https://www.academia.edu/28373142/Directions_for_a_psychology_research_agenda_in_cancer">Directions for a psychology research agenda in cancer</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28373142" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e2a72eeeac7551932b88861bd19c685e" rel="nofollow" data-download="{"attachment_id":48707195,"asset_id":28373142,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button 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class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/7619910/Mammalian_cyclin_dependent_kinases">Mammalian cyclin-dependent kinases</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Cyclin-dependent kinases (Cdks) are the catalytic subunits of a family of mammalian heterodimeric serine/threonine kinases that have been implicated in the control of cell-cycle progression, transcription and neuronal function. Recent... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_7619910" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Cyclin-dependent kinases (Cdks) are the catalytic subunits of a family of mammalian heterodimeric serine/threonine kinases that have been implicated in the control of cell-cycle progression, transcription and neuronal function. Recent genetic evidence obtained with gene-targeted mice has shown that Cdk4 and Cdk6 are not needed for entry into the cell cycle after mitogenic stimuli and organogenesis; however, they are essential for the proliferation of some endocrine and hematopoietic cells. Cdk2 is also dispensable for the mitotic cell cycle. Indeed, mice without Cdk2 are normal except for their complete sterility: unexpectedly, Cdk2 is crucial for the first meiotic division of male and female germ cells. These findings have important implications both for our current understanding of the role of Cdks in regulating the mammalian cell cycle and for their potential use as therapeutic targets in cancer.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/7619910" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e479c42985de66b08faa5c5dac966c16" rel="nofollow" data-download="{"attachment_id":48395628,"asset_id":7619910,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48395628/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="13767023" href="https://cnio.academia.edu/MarcosMalumbres">Marcos Malumbres</a><script data-card-contents-for-user="13767023" type="text/json">{"id":13767023,"first_name":"Marcos","last_name":"Malumbres","domain_name":"cnio","page_name":"MarcosMalumbres","display_name":"Marcos Malumbres","profile_url":"https://cnio.academia.edu/MarcosMalumbres?f_ri=469018","photo":"https://0.academia-photos.com/13767023/3996901/4668267/s65_marcos.malumbres.jpg_oh_4263c46553ddd754eb18f143ff350cdb_oe_545635e5___gda___1414414582_a3e8cfcd41047cecf392abecb0eab9dc"}</script></span></span></li><li class="js-paper-rank-work_7619910 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="7619910"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 7619910, container: ".js-paper-rank-work_7619910", }); 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Recent genetic evidence obtained with gene-targeted mice has shown that Cdk4 and Cdk6 are not needed for entry into the cell cycle after mitogenic stimuli and organogenesis; however, they are essential for the proliferation of some endocrine and hematopoietic cells. Cdk2 is also dispensable for the mitotic cell cycle. Indeed, mice without Cdk2 are normal except for their complete sterility: unexpectedly, Cdk2 is crucial for the first meiotic division of male and female germ cells. These findings have important implications both for our current understanding of the role of Cdks in regulating the mammalian cell cycle and for their potential use as therapeutic targets in cancer.","downloadable_attachments":[{"id":48395628,"asset_id":7619910,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":13767023,"first_name":"Marcos","last_name":"Malumbres","domain_name":"cnio","page_name":"MarcosMalumbres","display_name":"Marcos Malumbres","profile_url":"https://cnio.academia.edu/MarcosMalumbres?f_ri=469018","photo":"https://0.academia-photos.com/13767023/3996901/4668267/s65_marcos.malumbres.jpg_oh_4263c46553ddd754eb18f143ff350cdb_oe_545635e5___gda___1414414582_a3e8cfcd41047cecf392abecb0eab9dc"}],"research_interests":[{"id":9113,"name":"Cell Cycle","url":"https://www.academia.edu/Documents/in/Cell_Cycle?f_ri=469018","nofollow":false},{"id":47884,"name":"Biological 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Carron","profile_url":"https://independent.academia.edu/PierreLouisCarron?f_ri=469018","photo":"/images/s65_no_pic.png"},{"id":49641743,"first_name":"Gérard","last_name":"Motte","domain_name":"independent","page_name":"GerardMotte","display_name":"Gérard Motte","profile_url":"https://independent.academia.edu/GerardMotte?f_ri=469018","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk?f_ri=469018","nofollow":false},{"id":9003,"name":"Kidney transplantation","url":"https://www.academia.edu/Documents/in/Kidney_transplantation?f_ri=469018","nofollow":false},{"id":58379,"name":"Renal 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Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=469018"},{"id":584602,"name":"Geriatric Assessment","url":"https://www.academia.edu/Documents/in/Geriatric_Assessment?f_ri=469018"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=469018"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=469018"},{"id":900542,"name":"Selection Bias","url":"https://www.academia.edu/Documents/in/Selection_Bias?f_ri=469018"},{"id":1476689,"name":"Oncologist","url":"https://www.academia.edu/Documents/in/Oncologist?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14816223" data-work_id="14816223" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14816223/Serum_Fructosamine_and_Lipid_Profile_in_Children_with_Malignant_Diseases">Serum Fructosamine and Lipid Profile in Children with Malignant Diseases</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14816223" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f12b8d4927ef8bbfe1d756ac761fe49d" rel="nofollow" data-download="{"attachment_id":43877528,"asset_id":14816223,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43877528/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33775770" href="https://independent.academia.edu/MehmetTas1">Mehmet Tas</a><script data-card-contents-for-user="33775770" type="text/json">{"id":33775770,"first_name":"Mehmet","last_name":"Tas","domain_name":"independent","page_name":"MehmetTas1","display_name":"Mehmet Tas","profile_url":"https://independent.academia.edu/MehmetTas1?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14816223 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14816223"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14816223, container: ".js-paper-rank-work_14816223", }); });</script></li><li class="js-percentile-work_14816223 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14816223; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14816223"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14816223 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14816223"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14816223; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14816223]").text(description); $(".js-view-count-work_14816223").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14816223").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14816223"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="631" href="https://www.academia.edu/Documents/in/Pediatrics">Pediatrics</a>, <script data-card-contents-for-ri="631" type="text/json">{"id":631,"name":"Pediatrics","url":"https://www.academia.edu/Documents/in/Pediatrics?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a>, <script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14816223]'), work: {"id":14816223,"title":"Serum Fructosamine and Lipid Profile in Children with Malignant Diseases","created_at":"2015-08-10T03:31:47.431-07:00","url":"https://www.academia.edu/14816223/Serum_Fructosamine_and_Lipid_Profile_in_Children_with_Malignant_Diseases?f_ri=469018","dom_id":"work_14816223","summary":null,"downloadable_attachments":[{"id":43877528,"asset_id":14816223,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33775770,"first_name":"Mehmet","last_name":"Tas","domain_name":"independent","page_name":"MehmetTas1","display_name":"Mehmet Tas","profile_url":"https://independent.academia.edu/MehmetTas1?f_ri=469018","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":631,"name":"Pediatrics","url":"https://www.academia.edu/Documents/in/Pediatrics?f_ri=469018","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=469018","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=469018","nofollow":false},{"id":90514,"name":"Cholesterol","url":"https://www.academia.edu/Documents/in/Cholesterol?f_ri=469018"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=469018"},{"id":227299,"name":"Triglycerides","url":"https://www.academia.edu/Documents/in/Triglycerides?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"},{"id":801998,"name":"Lipid Profile","url":"https://www.academia.edu/Documents/in/Lipid_Profile?f_ri=469018"},{"id":1612404,"name":"Hexosamines","url":"https://www.academia.edu/Documents/in/Hexosamines?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15377502" data-work_id="15377502" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15377502/Krebs_alles_ganz_anders_Besonderheiten_onkologischer_Arzneimittel_aus_Sicht_der_Arzneimittelzulassung">Krebs - alles ganz anders? Besonderheiten onkologischer Arzneimittel aus Sicht der Arzneimittelzulassung</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15377502" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f96fcc8209b6d7f1260c0df04a346a86" rel="nofollow" data-download="{"attachment_id":43277074,"asset_id":15377502,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43277074/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34528520" href="https://independent.academia.edu/KarlBroich">Karl Broich</a><script data-card-contents-for-user="34528520" type="text/json">{"id":34528520,"first_name":"Karl","last_name":"Broich","domain_name":"independent","page_name":"KarlBroich","display_name":"Karl Broich","profile_url":"https://independent.academia.edu/KarlBroich?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_15377502 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15377502"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15377502, container: ".js-paper-rank-work_15377502", }); });</script></li><li class="js-percentile-work_15377502 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15377502; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_15377502"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_15377502 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="15377502"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15377502; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15377502]").text(description); $(".js-view-count-work_15377502").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_15377502").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="15377502"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="39" href="https://www.academia.edu/Documents/in/Marketing">Marketing</a>, <script data-card-contents-for-ri="39" type="text/json">{"id":39,"name":"Marketing","url":"https://www.academia.edu/Documents/in/Marketing?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6021" href="https://www.academia.edu/Documents/in/Cancer">Cancer</a>, <script data-card-contents-for-ri="6021" type="text/json">{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="10347" href="https://www.academia.edu/Documents/in/European_Union">European Union</a>, <script data-card-contents-for-ri="10347" type="text/json">{"id":10347,"name":"European Union","url":"https://www.academia.edu/Documents/in/European_Union?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15377502]'), work: {"id":15377502,"title":"Krebs - alles ganz anders? Besonderheiten onkologischer Arzneimittel aus Sicht der Arzneimittelzulassung","created_at":"2015-09-04T00:03:55.528-07:00","url":"https://www.academia.edu/15377502/Krebs_alles_ganz_anders_Besonderheiten_onkologischer_Arzneimittel_aus_Sicht_der_Arzneimittelzulassung?f_ri=469018","dom_id":"work_15377502","summary":null,"downloadable_attachments":[{"id":43277074,"asset_id":15377502,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34528520,"first_name":"Karl","last_name":"Broich","domain_name":"independent","page_name":"KarlBroich","display_name":"Karl Broich","profile_url":"https://independent.academia.edu/KarlBroich?f_ri=469018","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":39,"name":"Marketing","url":"https://www.academia.edu/Documents/in/Marketing?f_ri=469018","nofollow":false},{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=469018","nofollow":false},{"id":10347,"name":"European Union","url":"https://www.academia.edu/Documents/in/European_Union?f_ri=469018","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=469018","nofollow":false},{"id":50576,"name":"Germany","url":"https://www.academia.edu/Documents/in/Germany?f_ri=469018"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15714708" data-work_id="15714708" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15714708/Self_reported_physical_activity_behaviour_exercise_motivation_and_information_among_Danish_adult_cancer_patients_undergoing_chemotherapy">Self-reported physical activity behaviour; exercise motivation and information among Danish adult cancer patients undergoing chemotherapy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Physical activity is considered an important and determining factor for the cancer patient&#39;s physical well-being and quality of life. However, cancer treatment may disrupt the practice of physical activity, and the prevention of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_15714708" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Physical activity is considered an important and determining factor for the cancer patient&#39;s physical well-being and quality of life. However, cancer treatment may disrupt the practice of physical activity, and the prevention of sedentary lifestyles in cancer survivors is imperative. The current study aimed at investigating self-reported physical activity behaviour, exercise motivation and information in cancer patients undergoing chemotherapy. Using a cross-sectional design, 451 patients (18-65 years) completed a questionnaire assessing pre-illness and present physical activity; motivation and information received. Patients reported a significant decline in physical activity from pre-illness to the time in active treatment (p&lt;0.001). Amongst the respondents, 68% answered that they believed exercise to be beneficial; and 78% claimed not exercising as much as desired. Exercise barriers included fatigue (74%) and physical discomfort (45%). Present physical activity behaviour wa...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15714708" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5b9995686e074d53fb2189410e39923a" rel="nofollow" data-download="{"attachment_id":41203106,"asset_id":15714708,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41203106/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34904476" href="https://independent.academia.edu/MortenQuist">Morten Quist</a><script data-card-contents-for-user="34904476" type="text/json">{"id":34904476,"first_name":"Morten","last_name":"Quist","domain_name":"independent","page_name":"MortenQuist","display_name":"Morten Quist","profile_url":"https://independent.academia.edu/MortenQuist?f_ri=469018","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_15714708 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15714708"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15714708, container: ".js-paper-rank-work_15714708", }); });</script></li><li class="js-percentile-work_15714708 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15714708; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_15714708"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_15714708 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="15714708"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15714708; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15714708]").text(description); $(".js-view-count-work_15714708").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_15714708").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="15714708"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">25</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="588" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7470" href="https://www.academia.edu/Documents/in/Quality_of_life">Quality of life</a>, <script data-card-contents-for-ri="7470" type="text/json">{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="9112" href="https://www.academia.edu/Documents/in/Physical_Activity">Physical Activity</a>, <script data-card-contents-for-ri="9112" type="text/json">{"id":9112,"name":"Physical Activity","url":"https://www.academia.edu/Documents/in/Physical_Activity?f_ri=469018","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=469018","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15714708]'), work: {"id":15714708,"title":"Self-reported physical activity behaviour; 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However, cancer treatment may disrupt the practice of physical activity, and the prevention of sedentary lifestyles in cancer survivors is imperative. The current study aimed at investigating self-reported physical activity behaviour, exercise motivation and information in cancer patients undergoing chemotherapy. Using a cross-sectional design, 451 patients (18-65 years) completed a questionnaire assessing pre-illness and present physical activity; motivation and information received. Patients reported a significant decline in physical activity from pre-illness to the time in active treatment (p\u0026lt;0.001). Amongst the respondents, 68% answered that they believed exercise to be beneficial; and 78% claimed not exercising as much as desired. Exercise barriers included fatigue (74%) and physical discomfort (45%). 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A review</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/1427221" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9c71519cdc271f95a2c96211fb40368e" rel="nofollow" data-download="{"attachment_id":10203739,"asset_id":1427221,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/10203739/download_file?st=MTczMjQyMDU3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="1234344" href="https://soton.academia.edu/DeborahFenlon">Deborah Fenlon</a><script data-card-contents-for-user="1234344" type="text/json">{"id":1234344,"first_name":"Deborah","last_name":"Fenlon","domain_name":"soton","page_name":"DeborahFenlon","display_name":"Deborah Fenlon","profile_url":"https://soton.academia.edu/DeborahFenlon?f_ri=469018","photo":"https://0.academia-photos.com/1234344/448567/558991/s65_deborah.fenlon.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-1427221">+1</span><div class="hidden js-additional-users-1427221"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://lancaster.academia.edu/SheilaAPayne">Sheila A. 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Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=469018"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=469018"}]}, }) } })();</script></ul></li></ul></div></div></div><div class="u-taCenter Pagination"><ul class="pagination"><li class="next_page"><a href="/Documents/in/Neoplasms?after=50%2C1427221" rel="next">Next</a></li><li class="last next"><a href="/Documents/in/Neoplasms?page=last">Last »</a></li></ul></div></div><div class="hidden-xs hidden-sm"><div class="u-pl6x"><div style="width: 300px;"><div class="panel panel-flat u-mt7x"><div class="panel-heading u-p5x"><div class="u-tcGrayDark u-taCenter u-fw700 u-textUppercase">Related Topics</div></div><ul class="list-group"><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Antineoplastic_Agents">Antineoplastic 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