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GNAL - Wikipedia
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lang="arz" hreflang="arz" data-title="GNAL" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target"><span>مصرى</span></a></li><li class="interlanguage-link interwiki-tt mw-list-item"><a href="https://tt.wikipedia.org/wiki/GNAL" title="GNAL – Tatar" lang="tt" hreflang="tt" data-title="GNAL" data-language-autonym="Татарча / tatarça" data-language-local-name="Tatar" class="interlanguage-link-target"><span>Татарча / tatarça</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/GNAL" title="GNAL – Ukrainian" lang="uk" hreflang="uk" data-title="GNAL" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q18026230#sitelinks-wikipedia" title="Edit 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<div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">hide</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Protein-coding gene in the species Homo sapiens</div> <p class="mw-empty-elt"> </p> <table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">GNAL</th></tr><tr><td colspan="4" style="text-align:center"></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd">Identifiers</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/4388">GNAL</a></span>, DYT25, G protein subunit alpha L, HG1O</td></tr><tr><th scope="row" style="background-color:#c3fdb8">External IDs</th><td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/139312">139312</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:95774">95774</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=68222">68222</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=GNAL">GNAL</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000141404">GNAL - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_18.svg" class="mw-file-description" title="Chromosome 18 (human)"><img alt="Chromosome 18 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Ideogram_human_chromosome_18.svg/300px-Ideogram_human_chromosome_18.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Ideogram_human_chromosome_18.svg/450px-Ideogram_human_chromosome_18.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Ideogram_human_chromosome_18.svg/600px-Ideogram_human_chromosome_18.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Chromosome_18_(human)" class="mw-redirect" title="Chromosome 18 (human)">Chromosome 18 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_18_ideogram.svg" class="mw-file-description" title="Chromosome 18 (human)"><img alt="Chromosome 18 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/Human_chromosome_18_ideogram.svg/300px-Human_chromosome_18_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/Human_chromosome_18_ideogram.svg/450px-Human_chromosome_18_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/94/Human_chromosome_18_ideogram.svg/600px-Human_chromosome_18_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 37.737313531522px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for GNAL"><img alt="Genomic location for GNAL" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 43.7px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for GNAL"><img alt="Genomic location for GNAL" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">18p11.21</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">11,689,264 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">11,885,685 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_house_mouse_chromosome_18.svg" class="mw-file-description" title="Chromosome 18 (mouse)"><img alt="Chromosome 18 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Ideogram_house_mouse_chromosome_18.svg/260px-Ideogram_house_mouse_chromosome_18.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Ideogram_house_mouse_chromosome_18.svg/390px-Ideogram_house_mouse_chromosome_18.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Ideogram_house_mouse_chromosome_18.svg/520px-Ideogram_house_mouse_chromosome_18.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks">Chromosome 18 (mouse)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Ideogram_of_house_mouse_chromosome_18.svg" class="mw-file-description" title="Chromosome 18 (mouse)"><img alt="Chromosome 18 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/86/Ideogram_of_house_mouse_chromosome_18.svg/300px-Ideogram_of_house_mouse_chromosome_18.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/86/Ideogram_of_house_mouse_chromosome_18.svg/450px-Ideogram_of_house_mouse_chromosome_18.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/86/Ideogram_of_house_mouse_chromosome_18.svg/600px-Ideogram_of_house_mouse_chromosome_18.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 212.81186652122px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for GNAL"><img alt="Genomic location for GNAL" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 218.8px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for GNAL"><img alt="Genomic location for GNAL" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">18 E1|18 39.85 cM</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">67,221,287 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">67,359,863 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000141404">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">external globus pallidus</li><br /><li style="line-height: 137%;">lateral nuclear group of thalamus</li><br /><li style="line-height: 137%;">middle temporal gyrus</li><br /><li style="line-height: 137%;">nucleus accumbens</li><br /><li style="line-height: 137%;">entorhinal cortex</li><br /><li style="line-height: 137%;">pars compacta</li><br /><li style="line-height: 137%;">pons</li><br /><li style="line-height: 137%;">superior vestibular nucleus</li><br /><li style="line-height: 137%;">putamen</li><br /><li style="line-height: 137%;">caudate nucleus</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSMUSG00000024524">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">olfactory tubercle</li><br /><li style="line-height: 137%;">olfactory epithelium</li><br /><li style="line-height: 137%;">nucleus accumbens</li><br /><li style="line-height: 137%;">globus pallidus</li><br /><li style="line-height: 137%;">medial dorsal nucleus</li><br /><li style="line-height: 137%;">medial geniculate nucleus</li><br /><li style="line-height: 137%;">lateral septal nucleus</li><br /><li style="line-height: 137%;">superior frontal gyrus</li><br /><li style="line-height: 137%;">lateral geniculate nucleus</li><br /><li style="line-height: 137%;">medial vestibular nucleus</li></ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000141404">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:PBB_GE_GNAL_206355_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/56/PBB_GE_GNAL_206355_at_fs.png/250px-PBB_GE_GNAL_206355_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/56/PBB_GE_GNAL_206355_at_fs.png/375px-PBB_GE_GNAL_206355_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/56/PBB_GE_GNAL_206355_at_fs.png/500px-PBB_GE_GNAL_206355_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span><br /><br /><span typeof="mw:File"><a href="/wiki/File:PBB_GE_GNAL_206356_s_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/PBB_GE_GNAL_206356_s_at_fs.png/250px-PBB_GE_GNAL_206356_s_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/PBB_GE_GNAL_206356_s_at_fs.png/375px-PBB_GE_GNAL_206356_s_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/59/PBB_GE_GNAL_206356_s_at_fs.png/500px-PBB_GE_GNAL_206356_s_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span><br /><br /><span typeof="mw:File"><a href="/wiki/File:PBB_GE_GNAL_214071_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/ce/PBB_GE_GNAL_214071_at_fs.png/250px-PBB_GE_GNAL_214071_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/ce/PBB_GE_GNAL_214071_at_fs.png/375px-PBB_GE_GNAL_214071_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/ce/PBB_GE_GNAL_214071_at_fs.png/500px-PBB_GE_GNAL_214071_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/2774/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Molecular function</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0019001">guanyl nucleotide binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0000166">nucleotide binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005525">GTP binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046872">metal ion binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001664">G protein-coupled receptor binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0003924">GTPase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/">signal transducer activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031683">G-protein beta/gamma-subunit complex binding</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Cellular component</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005886">plasma membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070062">extracellular exosome</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005834">heterotrimeric G-protein complex</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Biological process</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007608">sensory perception of smell</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007191">adenylate cyclase-activating dopamine receptor signaling pathway</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007193">adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007189">adenylate cyclase-activating G protein-coupled receptor signaling pathway</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007165">signal transduction</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007190">activation of adenylate cyclase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007186">G protein-coupled receptor signaling pathway</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007188">adenylate cyclase-modulating G protein-coupled receptor signaling pathway</a></li></ul> </div></td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:#c3fdb8">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=2774&rn=1">2774</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=14680&rn=1">14680</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000141404;db=core">ENSG00000141404</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000024524;db=core">ENSMUSG00000024524</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P38405">P38405</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q8CGK7">Q8CGK7</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (mRNA)</th><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001142339">NM_001142339</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001261443">NM_001261443</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001261444">NM_001261444</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_002071">NM_002071</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_182978">NM_182978</a><br /></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001369387">NM_001369387</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_010307">NM_010307</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_177137">NM_177137</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (protein)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001135811">NP_001135811</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001248372">NP_001248372</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001248373">NP_001248373</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_892023">NP_892023</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001356316">NP_001356316</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_034437">NP_034437</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_796111">NP_796111</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr18:11689264-11885685">Chr 18: 11.69 – 11.89 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chr18:67221287-67359863">Chr 18: 67.22 – 67.36 Mb</a></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q18026230" class="extiw" title="d:Q18026230">View/Edit Human</a></td><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q18250874" class="extiw" title="d:Q18250874">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>Guanine nucleotide-binding protein G(olf) subunit alpha</b> is a <a href="/wiki/Protein" title="Protein">protein</a> that in humans is encoded by the <i>GNAL</i> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-pmid1302014_5-0" class="reference"><a href="#cite_note-pmid1302014-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-entrez_6-0" class="reference"><a href="#cite_note-entrez-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> Its main product is the <a href="/wiki/Heterotrimeric_G-protein" class="mw-redirect" title="Heterotrimeric G-protein">heterotrimeric G-protein</a> alpha subunit G<sub>olf</sub>-α, a member of the <a href="/wiki/Gs_alpha_subunit" title="Gs alpha subunit">Gs alpha subunit</a> family that is a key component of <a href="/wiki/G_protein-coupled_receptor" title="G protein-coupled receptor">G protein-coupled receptor</a>-regulated <a href="/wiki/Adenylyl_cyclase" title="Adenylyl cyclase">adenylyl cyclase</a> <a href="/wiki/Signal_transduction" title="Signal transduction">signal transduction</a> pathways in the <a href="/wiki/Olfactory_system" title="Olfactory system">olfactory system</a> and the <a href="/wiki/Striatum" title="Striatum">striatum</a> in the <a href="/wiki/Brain" title="Brain">brain</a>. It also mediated <a href="/wiki/D1_receptor" class="mw-redirect" title="D1 receptor">D1 receptor</a> signalling in the striatum and is hence involved in motor control.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=GNAL&action=edit&section=1" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Second_messenger_system" title="Second messenger system">Second messenger system</a></li> <li><a href="/wiki/G_protein-coupled_receptor" title="G protein-coupled receptor">G protein-coupled receptor</a></li> <li><a href="/wiki/Heterotrimeric_G_protein" title="Heterotrimeric G protein">Heterotrimeric G protein</a></li> <li><a href="/wiki/Adenylyl_cyclase" title="Adenylyl cyclase">Adenylyl cyclase</a></li> <li><a href="/wiki/Protein_kinase_A" title="Protein kinase A">Protein kinase A</a></li> <li><a href="/wiki/Olfactory_receptors" class="mw-redirect" title="Olfactory receptors">Olfactory receptors</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=GNAL&action=edit&section=2" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000141404">GRCh38: Ensembl release 89: ENSG00000141404</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000024524">GRCm38: Ensembl release 89: ENSMUSG00000024524</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=2774">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span 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title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D14680&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGNAL" class="Z3988"></span></span> </li> <li id="cite_note-pmid1302014-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid1302014_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWilkieGilbertOlsenChen1993" class="citation journal cs1">Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI, et al. (Jun 1993). <a rel="nofollow" class="external text" href="https://zenodo.org/record/1233383">"Evolution of the mammalian G protein alpha subunit multigene family"</a>. <i>Nat Genet</i>. <b>1</b> (2): 85–91. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fng0592-85">10.1038/ng0592-85</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1302014">1302014</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:31888533">31888533</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nat+Genet&rft.atitle=Evolution+of+the+mammalian+G+protein+alpha+subunit+multigene+family&rft.volume=1&rft.issue=2&rft.pages=85-91&rft.date=1993-06&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A31888533%23id-name%3DS2CID&rft_id=info%3Apmid%2F1302014&rft_id=info%3Adoi%2F10.1038%2Fng0592-85&rft.aulast=Wilkie&rft.aufirst=TM&rft.au=Gilbert%2C+DJ&rft.au=Olsen%2C+AS&rft.au=Chen%2C+XN&rft.au=Amatruda%2C+TT&rft.au=Korenberg%2C+JR&rft.au=Trask%2C+BJ&rft.au=de+Jong%2C+P&rft.au=Reed%2C+RR&rft.au=Simon%2C+MI&rft_id=https%3A%2F%2Fzenodo.org%2Frecord%2F1233383&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGNAL" class="Z3988"></span></span> </li> <li id="cite_note-entrez-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-entrez_6-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2774">"Entrez Gene: GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+GNAL+guanine+nucleotide+binding+protein+%28G+protein%29%2C+alpha+activating+activity+polypeptide%2C+olfactory+type&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D2774&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGNAL" class="Z3988"></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFZhuangBelluscioHen2000" class="citation journal cs1">Zhuang X, Belluscio L, Hen R (15 August 2000). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772608">"G<sub>OLFα</sub> Mediates Dopamine D 1 Receptor Signaling"</a>. <i>The Journal of Neuroscience</i>. <b>20</b> (16): RC91. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1523%2FJNEUROSCI.20-16-j0001.2000">10.1523/JNEUROSCI.20-16-j0001.2000</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772608">6772608</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10924528">10924528</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Neuroscience&rft.atitle=G%3Csub%3EOLF%CE%B1%3C%2Fsub%3E+Mediates+Dopamine+D+1+Receptor+Signaling&rft.volume=20&rft.issue=16&rft.pages=RC91&rft.date=2000-08-15&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6772608%23id-name%3DPMC&rft_id=info%3Apmid%2F10924528&rft_id=info%3Adoi%2F10.1523%2FJNEUROSCI.20-16-j0001.2000&rft.aulast=Zhuang&rft.aufirst=Xiaoxi&rft.au=Belluscio%2C+Leonardo&rft.au=Hen%2C+Rene&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6772608&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGNAL" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=GNAL&action=edit&section=3" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 30em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFZigmanWestermarkLaMendola1994" class="citation journal cs1">Zigman JM, Westermark GT, LaMendola J, et al. (1994). 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navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Intracellular_signaling_peptides_and_proteins" title="Template:Intracellular signaling peptides and proteins"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Intracellular_signaling_peptides_and_proteins" title="Template talk:Intracellular signaling peptides and proteins"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Intracellular_signaling_peptides_and_proteins" title="Special:EditPage/Template:Intracellular signaling peptides and proteins"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Intracellular_signaling_peptides_and_proteins" style="font-size:114%;margin:0 4em"><a href="/wiki/Intracellular_signaling_peptides_and_proteins" class="mw-redirect" title="Intracellular signaling peptides and proteins">Intracellular signaling peptides and proteins</a></div></th></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%">MAP</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>see <a href="/wiki/Template:MAP_kinase_pathway" title="Template:MAP kinase pathway">MAP kinase pathway</a></i></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%">Calcium</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Intracellular_calcium-sensing_proteins" title="Intracellular calcium-sensing proteins">Intracellular calcium-sensing proteins</a></li> <li><a href="/wiki/Calcineurin" title="Calcineurin">Calcineurin</a></li> <li><a href="/wiki/Ca2%2B/calmodulin-dependent_protein_kinase" class="mw-redirect" title="Ca2+/calmodulin-dependent protein kinase">Ca2+/calmodulin-dependent protein kinase</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%"><a href="/wiki/G_protein" title="G protein">G protein</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Heterotrimeric_G_protein" title="Heterotrimeric G protein">Heterotrimeric</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/CAMP-dependent_pathway" title="CAMP-dependent pathway">cAMP</a>:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Heterotrimeric_G_protein" title="Heterotrimeric G protein">Heterotrimeric G protein</a> <ul><li><a href="/wiki/Gs_alpha_subunit" title="Gs alpha subunit">Gs</a>/<a href="/wiki/Gi_alpha_subunit" title="Gi alpha subunit">Gi</a></li></ul></li> <li><a href="/wiki/Adenylate_cyclase" class="mw-redirect" title="Adenylate cyclase">Adenylate cyclase</a></li> <li><a href="/wiki/Cyclic_adenosine_monophosphate" title="Cyclic adenosine monophosphate">cAMP</a></li> <li><a href="/wiki/3%27,5%27-cyclic-AMP_phosphodiesterase" title="3',5'-cyclic-AMP phosphodiesterase">3',5'-cyclic-AMP phosphodiesterase</a></li> <li><a href="/wiki/Protein_kinase_A" title="Protein kinase A">Protein kinase A</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Cyclic_guanosine_monophosphate" title="Cyclic guanosine monophosphate">cGMP</a>:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Transducin" title="Transducin">Transducin</a></li> <li><a href="/wiki/Gustducin" title="Gustducin">Gustducin</a></li> <li><a href="/wiki/Guanylate_cyclase" title="Guanylate cyclase">Guanylate cyclase</a></li> <li><a href="/wiki/Cyclic_guanosine_monophosphate" title="Cyclic guanosine monophosphate">cGMP</a></li> <li><a href="/wiki/3%27,5%27-cyclic-GMP_phosphodiesterase" title="3',5'-cyclic-GMP phosphodiesterase">3',5'-cyclic-GMP phosphodiesterase</a></li> <li><a href="/wiki/CGMP-dependent_protein_kinase" title="CGMP-dependent protein kinase">Protein kinase G</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/G_alpha_subunit" title="G alpha subunit">G alpha subunit</a> G<sub>α</sub> <ul><li><a href="/wiki/GNAO1" title="GNAO1">GNAO1</a></li> <li><a href="/wiki/GNAI1" title="GNAI1">GNAI1</a></li> <li><a href="/wiki/GNAI2" title="GNAI2">GNAI2</a></li> <li><a href="/wiki/GNAI3" title="GNAI3">GNAI3</a></li> <li><a href="/wiki/GNAT1" title="GNAT1">GNAT1</a></li> <li><a href="/wiki/GNAT2" title="GNAT2">GNAT2</a></li> <li><a href="/wiki/GNAT3" title="GNAT3">GNAT3</a></li> <li><a href="/wiki/GNAZ" title="GNAZ">GNAZ</a></li> <li><a href="/wiki/GNAS_complex_locus" title="GNAS complex locus">GNAS</a></li> <li><a class="mw-selflink selflink">GNAL</a></li> <li><a href="/wiki/GNAQ" title="GNAQ">GNAQ</a></li> <li><a href="/wiki/GNA11" title="GNA11">GNA11</a></li> <li><a href="/wiki/GNA12" title="GNA12">GNA12</a></li> <li><a href="/wiki/GNA13" title="GNA13">GNA13</a></li> <li><a href="/wiki/GNA14" title="GNA14">GNA14</a></li> <li><a href="/w/index.php?title=GNA15/GNA16&action=edit&redlink=1" class="new" title="GNA15/GNA16 (page does not exist)">GNA15/GNA16</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/G_beta-gamma_complex" title="G beta-gamma complex">G beta-gamma complex</a> G<sub>β</sub> <ul><li><a href="/wiki/GNB1" title="GNB1">GNB1</a></li> <li><a href="/wiki/GNB2" title="GNB2">GNB2</a></li> <li><a href="/wiki/GNB3" title="GNB3">GNB3</a></li> <li><a href="/wiki/GNB4" title="GNB4">GNB4</a></li> <li><a href="/wiki/GNB5" title="GNB5">GNB5</a></li></ul></li> <li>G<sub>γ</sub> <ul><li><a href="/wiki/GNGT1" title="GNGT1">GNGT1</a></li> <li><a href="/wiki/GNGT2" title="GNGT2">GNGT2</a></li> <li><a href="/wiki/GNG2" title="GNG2">GNG2</a></li> <li><a href="/wiki/GNG3" title="GNG3">GNG3</a></li> <li><a href="/wiki/GNG4" title="GNG4">GNG4</a></li> <li><a href="/wiki/GNG5" title="GNG5">GNG5</a></li> <li><a href="/wiki/GNG7" title="GNG7">GNG7</a></li> <li><a href="/w/index.php?title=GNG8&action=edit&redlink=1" class="new" title="GNG8 (page does not exist)">GNG8</a></li> <li><a href="/w/index.php?title=GNG10&action=edit&redlink=1" class="new" title="GNG10 (page does not exist)">GNG10</a></li> <li><a href="/wiki/GNG11" title="GNG11">GNG11</a></li> <li><a href="/wiki/GNG12" title="GNG12">GNG12</a></li> <li><a href="/wiki/GNG13" title="GNG13">GNG13</a></li> <li><a href="/wiki/BSCL2" title="BSCL2">BSCL2</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/G_protein-coupled_receptor_kinase" title="G protein-coupled receptor kinase">G protein-coupled receptor kinase</a></li> <li><a href="/wiki/AMP-activated_protein_kinase" title="AMP-activated protein kinase">AMP-activated protein kinase</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Small_GTPase" title="Small GTPase">Monomeric</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ADP_ribosylation_factor" title="ADP ribosylation factor">ARFs</a></li> <li><a href="/wiki/Rab_(G-protein)" title="Rab (G-protein)">Rabs</a></li> <li><a href="/wiki/Ras_subfamily" class="mw-redirect" title="Ras subfamily">Ras</a> <ul><li><a href="/wiki/HRAS" title="HRAS">HRAS</a></li> <li><a href="/wiki/KRAS" title="KRAS">KRAS</a></li> <li><a href="/wiki/Neuroblastoma_RAS_viral_oncogene_homolog" title="Neuroblastoma RAS viral oncogene homolog">NRAS</a></li></ul></li> <li><a href="/wiki/Rho_family_of_GTPases" title="Rho family of GTPases">Rhos</a></li> <li><a href="/wiki/ADP_ribosylation_factor" title="ADP ribosylation factor">Arfs</a></li> <li><a href="/wiki/Ran_(gene)" class="mw-redirect" title="Ran (gene)">Ran</a></li> <li><a href="/wiki/RHEB" title="RHEB">Rhebs</a></li> <li><a href="/wiki/Rap_GTP-binding_protein" title="Rap GTP-binding protein">Raps</a></li> <li><a href="/wiki/RRAD_(gene)" title="RRAD (gene)">RGKs</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%">Cyclin</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cyclin-dependent_kinase_inhibitor_protein" title="Cyclin-dependent kinase inhibitor protein">Cyclin-dependent kinase inhibitor protein</a></li> <li><a href="/wiki/Cyclin-dependent_kinase" title="Cyclin-dependent kinase">Cyclin-dependent kinase</a></li> <li><a href="/wiki/Cyclin" title="Cyclin">Cyclin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%">Lipid</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Phosphoinositide_phospholipase_C" title="Phosphoinositide phospholipase C">Phosphoinositide phospholipase C</a></li> <li><a href="/wiki/Phospholipase_C" title="Phospholipase C">Phospholipase C</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%">Other <a href="/wiki/Protein_kinase" title="Protein kinase">protein kinase</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Serine/threonine-specific_protein_kinase" title="Serine/threonine-specific protein kinase">Serine/threonine</a>:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Casein_kinase" title="Casein kinase">Casein kinase</a> <ul><li><a href="/wiki/Casein_kinase_1" title="Casein kinase 1">1</a></li> <li><a href="/wiki/Casein_kinase_2" title="Casein kinase 2">2</a></li></ul></li> <li><a href="/wiki/EIF-2_kinase" title="EIF-2 kinase">eIF-2 kinase</a> <ul><li><a href="/wiki/EIF2AK3" title="EIF2AK3">EIF2AK3</a></li></ul></li> <li><a href="/wiki/Glycogen_synthase_kinase" class="mw-redirect" title="Glycogen synthase kinase">Glycogen synthase kinase</a> <ul><li><a href="/w/index.php?title=GSK1&action=edit&redlink=1" class="new" title="GSK1 (page does not exist)">GSK1</a></li> <li><a href="/w/index.php?title=GSK2&action=edit&redlink=1" class="new" title="GSK2 (page does not exist)">GSK2</a></li> <li><a href="/wiki/GSK-3" title="GSK-3">GSK-3</a></li> <li><a href="/wiki/GSK3A" title="GSK3A">GSK3A</a></li> <li><a href="/wiki/GSK3B" class="mw-redirect" title="GSK3B">GSK3B</a></li></ul></li> <li><a href="/wiki/I%CE%BAB_kinase" title="IκB kinase">IκB kinase</a> <ul><li><a href="/wiki/CHUK" title="CHUK">CHUK</a></li> <li><a href="/wiki/IKK2" title="IKK2">IKK2</a></li> <li><a href="/wiki/IKBKG" title="IKBKG">IKBKG</a></li></ul></li> <li><a href="/wiki/Interleukin-1_receptor_associated_kinase" title="Interleukin-1 receptor associated kinase">Interleukin-1 receptor associated kinase</a> <ul><li><a href="/wiki/IRAK1" title="IRAK1">IRAK1</a></li> <li><a href="/wiki/IRAK2" title="IRAK2">IRAK2</a></li> <li><a href="/wiki/IRAK3" title="IRAK3">IRAK3</a></li> <li><a href="/wiki/IRAK4" title="IRAK4">IRAK4</a></li></ul></li> <li><a href="/wiki/Lim_kinase" title="Lim kinase">Lim kinase</a> <ul><li><a href="/wiki/LIMK1" title="LIMK1">LIMK1</a></li> <li><a href="/wiki/LIMK2" title="LIMK2">LIMK2</a></li></ul></li> <li><a href="/wiki/P21-activated_kinases" title="P21-activated kinases">p21-activated kinases</a> <ul><li><a href="/wiki/PAK1" title="PAK1">PAK1</a></li> <li><a href="/wiki/PAK2" title="PAK2">PAK2</a></li> <li><a href="/wiki/PAK3" title="PAK3">PAK3</a></li> <li><a href="/wiki/PAK4" title="PAK4">PAK4</a></li></ul></li> <li><a href="/wiki/Rho-associated_protein_kinase" title="Rho-associated protein kinase">Rho-associated protein kinase</a> <ul><li><a href="/wiki/ROCK1" title="ROCK1">ROCK1</a></li> <li><a href="/wiki/ROCK2" title="ROCK2">ROCK2</a></li></ul></li> <li><a href="/wiki/Ribosomal_s6_kinase" title="Ribosomal s6 kinase">Ribosomal s6 kinase</a> <ul><li><a href="/wiki/RPS6KA1" title="RPS6KA1">RPS6KA1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Non-receptor_tyrosine_kinase" title="Non-receptor tyrosine kinase">Tyrosine</a>:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ZAP70" title="ZAP70">ZAP70</a></li> <li><a href="/w/index.php?title=Focal_adhesion_protein-tyrosine_kinase&action=edit&redlink=1" class="new" title="Focal adhesion protein-tyrosine kinase (page does not exist)">Focal adhesion protein-tyrosine kinase</a> <ul><li><a href="/wiki/PTK2" title="PTK2">PTK2</a></li> <li><a href="/wiki/PTK2B" title="PTK2B">PTK2B</a></li></ul></li> <li><a href="/wiki/Bruton%27s_tyrosine_kinase" title="Bruton's tyrosine kinase">BTK</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Serine/threonine/tyrosine</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Dual-specificity_kinase" title="Dual-specificity kinase">Dual-specificity kinase</a> <ul><li><a href="/wiki/DYRK1A" title="DYRK1A">DYRK1A</a></li> <li><a href="/wiki/DYRK1B" title="DYRK1B">DYRK1B</a></li> <li><a href="/wiki/DYRK2" title="DYRK2">DYRK2</a></li> <li><a href="/wiki/DYRK3" title="DYRK3">DYRK3</a></li> <li><a href="/w/index.php?title=DYRK4&action=edit&redlink=1" class="new" title="DYRK4 (page does not exist)">DYRK4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Arginine</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arginine_kinase" title="Arginine kinase">Arginine kinase</a></li> <li><a href="/w/index.php?title=McsB&action=edit&redlink=1" class="new" title="McsB (page does not exist)">McsB</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%">Other <a href="/wiki/Protein_phosphatase" title="Protein phosphatase">protein phosphatase</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Protein_serine/threonine_phosphatase" title="Protein serine/threonine phosphatase">Serine/threonine</a>:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Protein_phosphatase_2" title="Protein phosphatase 2">Protein phosphatase 2</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Protein_tyrosine_phosphatase" title="Protein tyrosine phosphatase">Tyrosine</a>:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Protein_tyrosine_phosphatase" title="Protein tyrosine phosphatase">protein tyrosine phosphatase</a>: <a href="/w/index.php?title=Receptor-like_protein_tyrosine_phosphatase&action=edit&redlink=1" class="new" title="Receptor-like protein tyrosine phosphatase (page does not exist)">Receptor-like protein tyrosine phosphatase</a></li> <li><a href="/wiki/Sh2_domain-containing_protein_tyrosine_phosphatase" class="mw-redirect" title="Sh2 domain-containing protein tyrosine phosphatase">Sh2 domain-containing protein tyrosine phosphatase</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">both:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Dual-specificity_phosphatase" title="Dual-specificity phosphatase">Dual-specificity phosphatase</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%"><a href="/wiki/Apoptosis" title="Apoptosis">Apoptosis</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>see <a href="/wiki/Template:Apoptosis_signaling_pathway" title="Template:Apoptosis signaling pathway">apoptosis signaling pathway</a></i></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%"><a href="/wiki/GTP-binding_protein_regulators" title="GTP-binding protein regulators">GTP-binding protein regulators</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>see <a href="/wiki/Template:GTP-binding_protein_regulators" title="Template:GTP-binding protein regulators">GTP-binding protein regulators</a></i></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="background-color: AntiqueWhite;width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ATF6" title="ATF6">Activating transcription factor 6</a></li> <li><a href="/wiki/Signal_transducing_adaptor_protein" title="Signal transducing adaptor protein">Signal transducing adaptor protein</a></li> <li><a href="/wiki/I%CE%BAB%CE%B1" title="IκBα">I-kappa B protein</a></li> <li><a href="/wiki/MUC4" class="mw-redirect" title="MUC4">Mucin-4</a></li> <li><a href="/wiki/Olfactory_marker_protein" title="Olfactory marker protein">Olfactory marker protein</a></li> <li><a href="/wiki/Phosphatidylethanolamine_binding_protein" class="mw-redirect" title="Phosphatidylethanolamine binding protein">Phosphatidylethanolamine binding protein</a></li> <li><a href="/wiki/EDARADD" title="EDARADD">EDARADD</a></li> <li><a href="/wiki/PRKCSH" title="PRKCSH">PRKCSH</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div><i>see also <a href="/wiki/Template:Deficiencies_of_intracellular_signaling_peptides_and_proteins" title="Template:Deficiencies of intracellular signaling peptides and proteins">deficiencies of intracellular signaling peptides and proteins</a></i></div></td></tr></tbody></table></div> <p><br /> </p> <style data-mw-deduplicate="TemplateStyles:r1012311289">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/File:DNA_stub.png" class="mw-file-description"><img alt="Stub icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/40px-DNA_stub.png" decoding="async" width="40" height="30" class="mw-file-element" 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