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Primary Prevention Research Papers - Academia.edu

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Medical Commission</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12852278" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a9c824b274ec4bc232f37367e3f91afe" rel="nofollow" data-download="{&quot;attachment_id&quot;:45891240,&quot;asset_id&quot;:12852278,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" 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type="text/json">{"id":922,"name":"Education","url":"https://www.academia.edu/Documents/in/Education?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4160" href="https://www.academia.edu/Documents/in/Eating_Disorders">Eating Disorders</a><script data-card-contents-for-ri="4160" type="text/json">{"id":4160,"name":"Eating Disorders","url":"https://www.academia.edu/Documents/in/Eating_Disorders?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12852278]'), work: {"id":12852278,"title":"How to minimise the health risks to athletes who compete in weight-sensitive sports review and position statement on behalf of the Ad Hoc Research Working Group on Body Composition, Health and Performance, under the auspices of the IOC Medical 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rheumatic heart disease in Africa: the Addis Ababa communiqué</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major causes of heart failure, stroke and death among African women and children, despite being preventable and imminently treatable. From 21 to 22 February 2015, the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72737591" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major causes of heart failure, stroke and death among African women and children, despite being preventable and imminently treatable. From 21 to 22 February 2015, the Social Cluster of the Africa Union Commission (AUC) hosted a consultation with RHD experts convened by the Pan-African Society of Cardiology (PASCAR) in Addis Ababa, Ethiopia, to develop a &amp;#39;roadmap&amp;#39; of key actions that need to be taken by governments to eliminate ARF and eradicate RHD in Africa. Seven priority areas for action were adopted: (1) create prospective disease registers at sentinel sites in affected countries to measure disease burden and track progress towards the reduction of mortality by 25% by the year 2025, (2) ensure an adequate supply of high-quality benzathine penicillin for the primary and secondary prevention of ARF/RHD, (3) improve access to reproductive health services for women with RHD and other non-communicable diseas...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72737591" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="530f425eb9a953ae3b6fd3c23ef2bd59" rel="nofollow" data-download="{&quot;attachment_id&quot;:81546587,&quot;asset_id&quot;:72737591,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81546587/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="55280565" href="https://independent.academia.edu/SulafaAli">Sulafa Ali</a><script data-card-contents-for-user="55280565" type="text/json">{"id":55280565,"first_name":"Sulafa","last_name":"Ali","domain_name":"independent","page_name":"SulafaAli","display_name":"Sulafa Ali","profile_url":"https://independent.academia.edu/SulafaAli?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_72737591 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72737591"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72737591, container: ".js-paper-rank-work_72737591", }); 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From 21 to 22 February 2015, the Social Cluster of the Africa Union Commission (AUC) hosted a consultation with RHD experts convened by the Pan-African Society of Cardiology (PASCAR) in Addis Ababa, Ethiopia, to develop a \u0026#39;roadmap\u0026#39; of key actions that need to be taken by governments to eliminate ARF and eradicate RHD in Africa. Seven priority areas for action were adopted: (1) create prospective disease registers at sentinel sites in affected countries to measure disease burden and track progress towards the reduction of mortality by 25% by the year 2025, (2) ensure an adequate supply of high-quality benzathine penicillin for the primary and secondary prevention of ARF/RHD, (3) improve access to reproductive health services for women with RHD and other non-communicable diseas...","downloadable_attachments":[{"id":81546587,"asset_id":72737591,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":55280565,"first_name":"Sulafa","last_name":"Ali","domain_name":"independent","page_name":"SulafaAli","display_name":"Sulafa Ali","profile_url":"https://independent.academia.edu/SulafaAli?f_ri=1292329","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4486,"name":"Political 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Prevention","url":"https://www.academia.edu/Documents/in/Primary_Prevention?f_ri=1292329"},{"id":1355491,"name":"Pregnancy Outcome","url":"https://www.academia.edu/Documents/in/Pregnancy_Outcome?f_ri=1292329"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_77058368" data-work_id="77058368" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/77058368/Abordagem_do_c%C3%A2ncer_da_boca_uma_estrat%C3%A9gia_para_os_n%C3%ADveis_prim%C3%A1rio_e_secund%C3%A1rio_de_aten%C3%A7%C3%A3o_em_sa%C3%BAde">Abordagem do câncer da boca: uma estratégia para os níveis primário e secundário de atenção em saúde</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">O avanço verificado no enfrentamento de neoplasias malignas por meio dos sistemas de saúde envolve melhorias nas áreas de vigilância, organização de redes de assistência, programas específicos voltados às prevenções primária e secundária... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_77058368" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">O avanço verificado no enfrentamento de neoplasias malignas por meio dos sistemas de saúde envolve melhorias nas áreas de vigilância, organização de redes de assistência, programas específicos voltados às prevenções primária e secundária e, obviamente, aos avanços técnico-científicos que caracterizam a abordagem diagnóstica e terapêutica. Embora seja notável o reconhecimento de avanços no manejo de neoplasias malignas em todas as áreas citadas, o câncer da boca permanece com indicadores de morbidade e mortalidade que parecem não acompanhar o acúmulo científico no conhecimento da doença. O presente manuscrito objetiva discutir os motivos desse descompasso, a necessidade de reorientação de prioridades na abordagem do câncer da boca e sua efetivação como política pública de saúde.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/77058368" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="95ac67f3bad5b4551820b33fe956de12" rel="nofollow" data-download="{&quot;attachment_id&quot;:84615052,&quot;asset_id&quot;:77058368,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/84615052/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33401020" href="https://usp-br.academia.edu/CelsoLemos">Celso A Lemos</a><script data-card-contents-for-user="33401020" type="text/json">{"id":33401020,"first_name":"Celso","last_name":"Lemos","domain_name":"usp-br","page_name":"CelsoLemos","display_name":"Celso A Lemos","profile_url":"https://usp-br.academia.edu/CelsoLemos?f_ri=1292329","photo":"https://0.academia-photos.com/33401020/44002755/34783101/s65_celso.lemos.jpg"}</script></span></span></li><li class="js-paper-rank-work_77058368 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="77058368"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 77058368, container: ".js-paper-rank-work_77058368", }); 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$(".js-view-count[data-work-id=77058368]").text(description); $(".js-view-count-work_77058368").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_77058368").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="77058368"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">11</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2974" href="https://www.academia.edu/Documents/in/Primary_Health_Care">Primary Health Care</a>,&nbsp;<script data-card-contents-for-ri="2974" type="text/json">{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="9821" href="https://www.academia.edu/Documents/in/Brazil">Brazil</a>,&nbsp;<script data-card-contents-for-ri="9821" type="text/json">{"id":9821,"name":"Brazil","url":"https://www.academia.edu/Documents/in/Brazil?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17969" href="https://www.academia.edu/Documents/in/Health_Policy">Health Policy</a>,&nbsp;<script data-card-contents-for-ri="17969" type="text/json">{"id":17969,"name":"Health Policy","url":"https://www.academia.edu/Documents/in/Health_Policy?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=77058368]'), work: {"id":77058368,"title":"Abordagem do câncer da boca: uma estratégia para os níveis primário e secundário de atenção em saúde","created_at":"2022-04-20T04:18:41.696-07:00","url":"https://www.academia.edu/77058368/Abordagem_do_c%C3%A2ncer_da_boca_uma_estrat%C3%A9gia_para_os_n%C3%ADveis_prim%C3%A1rio_e_secund%C3%A1rio_de_aten%C3%A7%C3%A3o_em_sa%C3%BAde?f_ri=1292329","dom_id":"work_77058368","summary":"O avanço verificado no enfrentamento de neoplasias malignas por meio dos sistemas de saúde envolve melhorias nas áreas de vigilância, organização de redes de assistência, programas específicos voltados às prevenções primária e secundária e, obviamente, aos avanços técnico-científicos que caracterizam a abordagem diagnóstica e terapêutica. Embora seja notável o reconhecimento de avanços no manejo de neoplasias malignas em todas as áreas citadas, o câncer da boca permanece com indicadores de morbidade e mortalidade que parecem não acompanhar o acúmulo científico no conhecimento da doença. O presente manuscrito objetiva discutir os motivos desse descompasso, a necessidade de reorientação de prioridades na abordagem do câncer da boca e sua efetivação como política pública de saúde.","downloadable_attachments":[{"id":84615052,"asset_id":77058368,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33401020,"first_name":"Celso","last_name":"Lemos","domain_name":"usp-br","page_name":"CelsoLemos","display_name":"Celso A Lemos","profile_url":"https://usp-br.academia.edu/CelsoLemos?f_ri=1292329","photo":"https://0.academia-photos.com/33401020/44002755/34783101/s65_celso.lemos.jpg"}],"research_interests":[{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care?f_ri=1292329","nofollow":false},{"id":9821,"name":"Brazil","url":"https://www.academia.edu/Documents/in/Brazil?f_ri=1292329","nofollow":false},{"id":17969,"name":"Health 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href="https://www.academia.edu/54272921/Benefit_risk_assessment_in_a_post_market_setting_a_case_study_integrating_real_life_experience_into_benefit_risk_methodology">Benefit-risk assessment in a post-market setting: a case study integrating real-life experience into benefit-risk methodology</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/54272921" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4b1828efb6ebbd511e17edc26e19e253" rel="nofollow" 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Africa in the year 2000</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Various approaches to preventing mother-to-child transmission (MTCT) of HIV have recently been, or are being, evaluated in developing countries, especially in Africa. New findings from these trials are now becoming available, the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14359031" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Various approaches to preventing mother-to-child transmission (MTCT) of HIV have recently been, or are being, evaluated in developing countries, especially in Africa. New findings from these trials are now becoming available, the implications of which, for population-based intervention programmes, need urgent consideration. A critical review of 18 randomized trials and other relevant studies from developing and industrialized countries. Most African results relate to trials of antiretroviral agents (ARV). They demonstrate efficacy in reducing transmission in the first 6 months of life with short regimens of zidovudine (ZDV), with or without lamivudine (3TC), and nevirapine (NVP) alone. Preliminary results suggest the long-term efficacy of zidovudine. Antiseptic and nutritional interventions have been shown to reduce maternal and infant mortality and morbidity but not MTCT of HIV. HIV confidential voluntary counselling and testing for pregnant women, a short regimen of peripartum ARV...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14359031" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7acd3487d59f42f956e3dd4d3249f62c" rel="nofollow" data-download="{&quot;attachment_id&quot;:44285447,&quot;asset_id&quot;:14359031,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44285447/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33303779" href="https://u-bordeaux1.academia.edu/Val%C3%A9rianeLeroy">Valériane Leroy</a><script data-card-contents-for-user="33303779" type="text/json">{"id":33303779,"first_name":"Valériane","last_name":"Leroy","domain_name":"u-bordeaux1","page_name":"ValérianeLeroy","display_name":"Valériane Leroy","profile_url":"https://u-bordeaux1.academia.edu/Val%C3%A9rianeLeroy?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-14359031">+1</span><div class="hidden js-additional-users-14359031"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/MarielouiseNewell">Marie-louise Newell</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-14359031'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-14359031').html(); 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New findings from these trials are now becoming available, the implications of which, for population-based intervention programmes, need urgent consideration. A critical review of 18 randomized trials and other relevant studies from developing and industrialized countries. Most African results relate to trials of antiretroviral agents (ARV). They demonstrate efficacy in reducing transmission in the first 6 months of life with short regimens of zidovudine (ZDV), with or without lamivudine (3TC), and nevirapine (NVP) alone. Preliminary results suggest the long-term efficacy of zidovudine. Antiseptic and nutritional interventions have been shown to reduce maternal and infant mortality and morbidity but not MTCT of HIV. HIV confidential voluntary counselling and testing for pregnant women, a short regimen of peripartum ARV...","downloadable_attachments":[{"id":44285447,"asset_id":14359031,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33303779,"first_name":"Valériane","last_name":"Leroy","domain_name":"u-bordeaux1","page_name":"ValérianeLeroy","display_name":"Valériane Leroy","profile_url":"https://u-bordeaux1.academia.edu/Val%C3%A9rianeLeroy?f_ri=1292329","photo":"/images/s65_no_pic.png"},{"id":38445293,"first_name":"Marie-louise","last_name":"Newell","domain_name":"independent","page_name":"MarielouiseNewell","display_name":"Marie-louise Newell","profile_url":"https://independent.academia.edu/MarielouiseNewell?f_ri=1292329","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":184,"name":"Sociology","url":"https://www.academia.edu/Documents/in/Sociology?f_ri=1292329","nofollow":false},{"id":202,"name":"Program 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itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18532554/Prevention_of_Preeclampsia">Prevention of Preeclampsia</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Preeclampsia (PE) affects around 2-5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In an attempt to prevent preeclampsia, many strategies based on antenatal care, change in lifestyle,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_18532554" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Preeclampsia (PE) affects around 2-5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In an attempt to prevent preeclampsia, many strategies based on antenatal care, change in lifestyle, nutritional supplementation, and drugs have been studied. The aim of this paper is to review recent evidence about primary and secondary prevention of preeclampsia.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18532554" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="31ec61e6e9bd3131c11bf7cfe0f9a1e5" rel="nofollow" data-download="{&quot;attachment_id&quot;:42160807,&quot;asset_id&quot;:18532554,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42160807/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38563901" href="https://westernu.academia.edu/LaudelinoLopes">LAUDELINO M LOPES</a><script data-card-contents-for-user="38563901" type="text/json">{"id":38563901,"first_name":"LAUDELINO","last_name":"LOPES","domain_name":"westernu","page_name":"LaudelinoLopes","display_name":"LAUDELINO M LOPES","profile_url":"https://westernu.academia.edu/LaudelinoLopes?f_ri=1292329","photo":"https://0.academia-photos.com/38563901/10711381/11957543/s65_laudelino.lopes.jpg"}</script></span></span></li><li class="js-paper-rank-work_18532554 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18532554"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18532554, container: ".js-paper-rank-work_18532554", }); 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$(".js-view-count[data-work-id=18532554]").text(description); $(".js-view-count-work_18532554").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_18532554").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="18532554"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">16</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="9534" href="https://www.academia.edu/Documents/in/Calcium">Calcium</a>,&nbsp;<script data-card-contents-for-ri="9534" type="text/json">{"id":9534,"name":"Calcium","url":"https://www.academia.edu/Documents/in/Calcium?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="25443" href="https://www.academia.edu/Documents/in/Exercise_therapy">Exercise therapy</a>,&nbsp;<script data-card-contents-for-ri="25443" type="text/json">{"id":25443,"name":"Exercise therapy","url":"https://www.academia.edu/Documents/in/Exercise_therapy?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="51711" href="https://www.academia.edu/Documents/in/Antioxidants">Antioxidants</a>,&nbsp;<script data-card-contents-for-ri="51711" type="text/json">{"id":51711,"name":"Antioxidants","url":"https://www.academia.edu/Documents/in/Antioxidants?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62550" href="https://www.academia.edu/Documents/in/Pregnancy">Pregnancy</a><script data-card-contents-for-ri="62550" type="text/json">{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=18532554]'), work: {"id":18532554,"title":"Prevention of Preeclampsia","created_at":"2015-11-17T13:23:23.872-08:00","url":"https://www.academia.edu/18532554/Prevention_of_Preeclampsia?f_ri=1292329","dom_id":"work_18532554","summary":"Preeclampsia (PE) affects around 2-5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In an attempt to prevent preeclampsia, many strategies based on antenatal care, change in lifestyle, nutritional supplementation, and drugs have been studied. 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The German health examination as defined in section 25 of the Social Code Book V... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72393864" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The purpose of periodic health examinations is to prevent disease through early intervention and through stratifying individual patients&amp;#39; health risk. The German health examination as defined in section 25 of the Social Code Book V (Sozialgesetzbuch V) seems to be outdated in many respects. In order to develop an alternative to the current German system an international comparison of periodic health examinations in other healthcare systems is useful. The study investigates the measures taken for primary prevention of cardiovascular disease in seven countries. Content, implementation and organisation of the various programmes are analysed in the present paper. The present study was designed as a qualitative multiple case study. The collection of data on cardiovascular screening programmes in the seven different healthcare systems in this study relies on information publicly available on the Internet. The data were entered into a matrix which had been created prior to the data col...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72393864" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="033f46980b645fa470928328180ce101" rel="nofollow" data-download="{&quot;attachment_id&quot;:81336549,&quot;asset_id&quot;:72393864,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81336549/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37452235" href="https://uni-marburg1.academia.edu/NorbertDonnerbanzhoff">Norbert Donner-banzhoff</a><script data-card-contents-for-user="37452235" type="text/json">{"id":37452235,"first_name":"Norbert","last_name":"Donner-banzhoff","domain_name":"uni-marburg1","page_name":"NorbertDonnerbanzhoff","display_name":"Norbert Donner-banzhoff","profile_url":"https://uni-marburg1.academia.edu/NorbertDonnerbanzhoff?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_72393864 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72393864"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72393864, container: ".js-paper-rank-work_72393864", }); 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$(".js-view-count[data-work-id=72393864]").text(description); $(".js-view-count-work_72393864").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_72393864").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="72393864"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">14</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3645" href="https://www.academia.edu/Documents/in/Evidence_Based_Medicine">Evidence Based Medicine</a>,&nbsp;<script data-card-contents-for-ri="3645" type="text/json">{"id":3645,"name":"Evidence Based Medicine","url":"https://www.academia.edu/Documents/in/Evidence_Based_Medicine?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12135" href="https://www.academia.edu/Documents/in/Qualitative_Research">Qualitative Research</a>,&nbsp;<script data-card-contents-for-ri="12135" type="text/json">{"id":12135,"name":"Qualitative Research","url":"https://www.academia.edu/Documents/in/Qualitative_Research?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="50576" href="https://www.academia.edu/Documents/in/Germany">Germany</a>,&nbsp;<script data-card-contents-for-ri="50576" type="text/json">{"id":50576,"name":"Germany","url":"https://www.academia.edu/Documents/in/Germany?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="57511" href="https://www.academia.edu/Documents/in/Cross-Cultural_Comparison">Cross-Cultural Comparison</a><script data-card-contents-for-ri="57511" type="text/json">{"id":57511,"name":"Cross-Cultural Comparison","url":"https://www.academia.edu/Documents/in/Cross-Cultural_Comparison?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72393864]'), work: {"id":72393864,"title":"[Periodic health examinations - an international comparison]","created_at":"2022-02-24T02:44:31.497-08:00","url":"https://www.academia.edu/72393864/_Periodic_health_examinations_an_international_comparison_?f_ri=1292329","dom_id":"work_72393864","summary":"The purpose of periodic health examinations is to prevent disease through early intervention and through stratifying individual patients\u0026#39; health risk. The German health examination as defined in section 25 of the Social Code Book V (Sozialgesetzbuch V) seems to be outdated in many respects. In order to develop an alternative to the current German system an international comparison of periodic health examinations in other healthcare systems is useful. The study investigates the measures taken for primary prevention of cardiovascular disease in seven countries. Content, implementation and organisation of the various programmes are analysed in the present paper. The present study was designed as a qualitative multiple case study. The collection of data on cardiovascular screening programmes in the seven different healthcare systems in this study relies on information publicly available on the Internet. 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type="text/json">{"id":922,"name":"Education","url":"https://www.academia.edu/Documents/in/Education?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1697" href="https://www.academia.edu/Documents/in/Violence">Violence</a>,&nbsp;<script data-card-contents-for-ri="1697" type="text/json">{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3208" href="https://www.academia.edu/Documents/in/Homicide">Homicide</a>,&nbsp;<script data-card-contents-for-ri="3208" type="text/json">{"id":3208,"name":"Homicide","url":"https://www.academia.edu/Documents/in/Homicide?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4307" href="https://www.academia.edu/Documents/in/Behavior">Behavior</a><script data-card-contents-for-ri="4307" type="text/json">{"id":4307,"name":"Behavior","url":"https://www.academia.edu/Documents/in/Behavior?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=4020332]'), work: {"id":4020332,"title":"Youth violence","created_at":"2013-07-13T02:06:28.022-07:00","url":"https://www.academia.edu/4020332/Youth_violence?f_ri=1292329","dom_id":"work_4020332","summary":null,"downloadable_attachments":[{"id":50079177,"asset_id":4020332,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3552276,"first_name":"Lloyd","last_name":"Potter","domain_name":"utsa","page_name":"LloydPotter","display_name":"Lloyd 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class="InlineList-item-text" data-has-card-for-ri="981" href="https://www.academia.edu/Documents/in/Health_Promotion">Health Promotion</a>,&nbsp;<script data-card-contents-for-ri="981" type="text/json">{"id":981,"name":"Health Promotion","url":"https://www.academia.edu/Documents/in/Health_Promotion?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1786" href="https://www.academia.edu/Documents/in/Social_Marketing">Social Marketing</a>,&nbsp;<script data-card-contents-for-ri="1786" type="text/json">{"id":1786,"name":"Social Marketing","url":"https://www.academia.edu/Documents/in/Social_Marketing?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4441" href="https://www.academia.edu/Documents/in/Health_Care">Health Care</a>,&nbsp;<script data-card-contents-for-ri="4441" type="text/json">{"id":4441,"name":"Health 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Prevention","url":"https://www.academia.edu/Documents/in/Primary_Prevention?f_ri=1292329"},{"id":2246318,"name":"Motor activity","url":"https://www.academia.edu/Documents/in/Motor_activity?f_ri=1292329"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19324000" data-work_id="19324000" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/19324000/Executive_Summary_of_the_National_Cancer_Institute_Workshop_Highlights_and_recommendations">Executive Summary of the National Cancer Institute Workshop: Highlights and recommendations</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Prostate cancer chemoprevention represents a relatively new and promising strategy for reducing the immense public health burden of this devastating cancer of men in the United States and Western societies. Chemoprevention is defined as... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_19324000" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Prostate cancer chemoprevention represents a relatively new and promising strategy for reducing the immense public health burden of this devastating cancer of men in the United States and Western societies. Chemoprevention is defined as the administration of agents (drugs, biologics, and natural products) that modulate (inhibit) one or more steps in the multistage carcinogenesis process culminating in invasive adenocarcinoma of the prostate. In 2000, there were an estimated 170,000 new cases of prostate cancer and 31,000 deaths in the United States. During the past decade, the National Cancer Institute (NCI) organized the chemoprevention research program and began testing the first generation of promising agents (eg, 4-(hydroxy)-fenretinide [4-HPR], difluoromethylornithine [DFMO], antiandrogens) in high-risk cohorts and launched the first-large scale US phase 3 primary prevention trial, known as Prostate Cancer Prevention Trial (PCPT-1), in 18,000 average-risk men (age more than 55 years and prostate-specific antigen [PSA] less than 3 ng/mL) treated for 7 years with finasteride or placebo. In the summer of 1998, the NCI Prostate Cancer Progress Review Group (PRG) Report to the director of NCI was published in response to the leadership of the prostate cancer advocacy community in conjunction with Congress. To further elucidate and address critical issues identified in this report and to develop a research agenda for the newly created Prostate and Urologic Cancer Research Group in the Division of Cancer Prevention at NCI, the NCI organized the workshop &amp;amp;quot;New Clinical Trial Strategies for Prostate Cancer Chemoprevention.&amp;amp;quot; The major objectives were to promote understanding and cooperation among the NCI, US Food and Drug Administration (FDA), academia, pharmaceutical industry, and the public regarding new opportunities for clinical prevention trials for prostate cancer. The workshop was divided into three concurrent breakout panels and a fourth joint integrative panel. The workshop addressed multiple key areas identified in the PRG report in the following panels: (1) Molecular Targets and Promising Agents in Clinical Development; (2) Intermediate Endpoint Biomarkers for Prevention Trials; (3) High-Risk Study Populations for Prevention Trials, and (4) Preventive Clinical Trial Designs and Regulatory Issues. Expert panelists were drawn from leading academic, pharmaceutical, and government scientists in basic research and clinical investigation. Key pharmaceutical, biotechnology, academic, and National Institutes of Health scientists presented overviews of their new agents and products in clinical development (representing the next generation of promising agents). Senior FDA physicians from the Center for Drugs and Center for Biologics presented on current standards for new drug and biologic approval for chemoprevention efficacy. Some of the key topics included recent advances in the state of knowledge of promising agents in the clinic based on molecular targets as well as bottlenecks in drug development for pharmaceutical sponsors; strategic modulable biomarkers that can serve as primary endpoints in phase 1/2 trials to assess preventive efficacy; high-risk cohorts with precancer (high-grade prostatic intraepithelial neoplasia) and representative clinical trial designs that are ready for immediate translation into efficient prevention trials, such as Bayesian sequential monitoring for early assessment of biologic activity and factorial designs for assessment of multiagent combinations. Finally, each expert panel generated recommendations for areas of future research emphasizing opportunities and infrastructure needs.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/19324000" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="25675d0b5cad19ade384735daf78491d" rel="nofollow" data-download="{&quot;attachment_id&quot;:42097996,&quot;asset_id&quot;:19324000,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42097996/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39578858" href="https://independent.academia.edu/FrankMeyskens">Frank Meyskens</a><script data-card-contents-for-user="39578858" type="text/json">{"id":39578858,"first_name":"Frank","last_name":"Meyskens","domain_name":"independent","page_name":"FrankMeyskens","display_name":"Frank Meyskens","profile_url":"https://independent.academia.edu/FrankMeyskens?f_ri=1292329","photo":"https://0.academia-photos.com/39578858/18605047/18570056/s65_frank.meyskens.jpg"}</script></span></span></li><li class="js-paper-rank-work_19324000 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="19324000"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 19324000, container: ".js-paper-rank-work_19324000", }); });</script></li><li class="js-percentile-work_19324000 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 19324000; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_19324000"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_19324000 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="19324000"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 19324000; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=19324000]").text(description); $(".js-view-count-work_19324000").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_19324000").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="19324000"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">27</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="653" href="https://www.academia.edu/Documents/in/Urology">Urology</a>,&nbsp;<script data-card-contents-for-ri="653" type="text/json">{"id":653,"name":"Urology","url":"https://www.academia.edu/Documents/in/Urology?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="2789" href="https://www.academia.edu/Documents/in/Government">Government</a>,&nbsp;<script data-card-contents-for-ri="2789" type="text/json">{"id":2789,"name":"Government","url":"https://www.academia.edu/Documents/in/Government?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4531" href="https://www.academia.edu/Documents/in/Clinical_Trial">Clinical Trial</a>,&nbsp;<script data-card-contents-for-ri="4531" type="text/json">{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12980" href="https://www.academia.edu/Documents/in/Prostate_Cancer">Prostate Cancer</a><script data-card-contents-for-ri="12980" type="text/json">{"id":12980,"name":"Prostate Cancer","url":"https://www.academia.edu/Documents/in/Prostate_Cancer?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=19324000]'), work: {"id":19324000,"title":"Executive Summary of the National Cancer Institute Workshop: Highlights and recommendations","created_at":"2015-12-01T15:09:40.177-08:00","url":"https://www.academia.edu/19324000/Executive_Summary_of_the_National_Cancer_Institute_Workshop_Highlights_and_recommendations?f_ri=1292329","dom_id":"work_19324000","summary":"Prostate cancer chemoprevention represents a relatively new and promising strategy for reducing the immense public health burden of this devastating cancer of men in the United States and Western societies. Chemoprevention is defined as the administration of agents (drugs, biologics, and natural products) that modulate (inhibit) one or more steps in the multistage carcinogenesis process culminating in invasive adenocarcinoma of the prostate. In 2000, there were an estimated 170,000 new cases of prostate cancer and 31,000 deaths in the United States. During the past decade, the National Cancer Institute (NCI) organized the chemoprevention research program and began testing the first generation of promising agents (eg, 4-(hydroxy)-fenretinide [4-HPR], difluoromethylornithine [DFMO], antiandrogens) in high-risk cohorts and launched the first-large scale US phase 3 primary prevention trial, known as Prostate Cancer Prevention Trial (PCPT-1), in 18,000 average-risk men (age more than 55 years and prostate-specific antigen [PSA] less than 3 ng/mL) treated for 7 years with finasteride or placebo. In the summer of 1998, the NCI Prostate Cancer Progress Review Group (PRG) Report to the director of NCI was published in response to the leadership of the prostate cancer advocacy community in conjunction with Congress. To further elucidate and address critical issues identified in this report and to develop a research agenda for the newly created Prostate and Urologic Cancer Research Group in the Division of Cancer Prevention at NCI, the NCI organized the workshop \u0026amp;quot;New Clinical Trial Strategies for Prostate Cancer Chemoprevention.\u0026amp;quot; The major objectives were to promote understanding and cooperation among the NCI, US Food and Drug Administration (FDA), academia, pharmaceutical industry, and the public regarding new opportunities for clinical prevention trials for prostate cancer. The workshop was divided into three concurrent breakout panels and a fourth joint integrative panel. The workshop addressed multiple key areas identified in the PRG report in the following panels: (1) Molecular Targets and Promising Agents in Clinical Development; (2) Intermediate Endpoint Biomarkers for Prevention Trials; (3) High-Risk Study Populations for Prevention Trials, and (4) Preventive Clinical Trial Designs and Regulatory Issues. Expert panelists were drawn from leading academic, pharmaceutical, and government scientists in basic research and clinical investigation. Key pharmaceutical, biotechnology, academic, and National Institutes of Health scientists presented overviews of their new agents and products in clinical development (representing the next generation of promising agents). Senior FDA physicians from the Center for Drugs and Center for Biologics presented on current standards for new drug and biologic approval for chemoprevention efficacy. Some of the key topics included recent advances in the state of knowledge of promising agents in the clinic based on molecular targets as well as bottlenecks in drug development for pharmaceutical sponsors; strategic modulable biomarkers that can serve as primary endpoints in phase 1/2 trials to assess preventive efficacy; high-risk cohorts with precancer (high-grade prostatic intraepithelial neoplasia) and representative clinical trial designs that are ready for immediate translation into efficient prevention trials, such as Bayesian sequential monitoring for early assessment of biologic activity and factorial designs for assessment of multiagent combinations. 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This systematic review of controlled trials evaluates the effectiveness of interventions to prevent BP episodes in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_25132587" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Back problems (BPs), with their cost and disability, are a substantial burden for individuals, employers, and society. This systematic review of controlled trials evaluates the effectiveness of interventions to prevent BP episodes in working age adults. We searched MEDLINE/EMBASE through May 2007, and COCHRANE/Trials Registry through August 22, 2008 using search terms of back pain, back injuries or sciatica, linked to prevention, control, workplace interventions, or ergonomics and searched article bibliographies. For systematic review inclusion, articles had to describe prospective controlled trials of interventions to prevent BPs in working-age adults, with intervention assignment either to individual participants or preexisting groups. Of 185 articles identified as potentially relevant, 20 trials (11%) met inclusion criteria. Researchers extracted relevant information from controlled trials and graded methodological quality. Because of heterogeneity of trials, meta-analysis was no...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25132587" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="aab50528a5d5cdd60dd7584f4a306276" rel="nofollow" data-download="{&quot;attachment_id&quot;:45453246,&quot;asset_id&quot;:25132587,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45453246/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32913372" href="https://washington.academia.edu/JudithMalmgren">Judith Malmgren</a><script data-card-contents-for-user="32913372" type="text/json">{"id":32913372,"first_name":"Judith","last_name":"Malmgren","domain_name":"washington","page_name":"JudithMalmgren","display_name":"Judith Malmgren","profile_url":"https://washington.academia.edu/JudithMalmgren?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25132587 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25132587"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25132587, container: ".js-paper-rank-work_25132587", }); 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Harold E. Shinitzky is an Instructor, Department of Pediatrics, Johns Hopkins University, School of Medicine, Baltimore, Maryland. Joan Kub is an Assistant Professor, Johns Hopkins University School of Nursing, Baltimore, Maryland.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/69447195" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="010b24e528f0bf6391262ef46c6db9c4" rel="nofollow" data-download="{&quot;attachment_id&quot;:79542370,&quot;asset_id&quot;:69447195,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/79542370/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="185657924" href="https://independent.academia.edu/HShinitzky">Harold Shinitzky</a><script data-card-contents-for-user="185657924" type="text/json">{"id":185657924,"first_name":"Harold","last_name":"Shinitzky","domain_name":"independent","page_name":"HShinitzky","display_name":"Harold Shinitzky","profile_url":"https://independent.academia.edu/HShinitzky?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_69447195 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="69447195"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 69447195, container: ".js-paper-rank-work_69447195", }); 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data-work_id="18365677" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18365677/Childhood_obesity_Prevention_practices_of_nurse_practitioners">Childhood obesity: Prevention practices of nurse practitioners</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The purposes or this study were to (a) describe the prevention practices of nurse practitioners (NPs) regarding childhood obesity, (b) compare the practices of NPs by specialty, practice setting, and awareness of childhood obesity... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_18365677" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The purposes or this study were to (a) describe the prevention practices of nurse practitioners (NPs) regarding childhood obesity, (b) compare the practices of NPs by specialty, practice setting, and awareness of childhood obesity prevention guidelines, (c) identify relationships between prevention practices and demographic variables of NPs, and (d) examine the resources for and barriers to implementing prevention practices. A convenience sample of 99 family NPs (FNPs) and pediatric NPs (PNPs) from the Intermountain area was used. Participants completed a questionnaire based on documented risk factors for childhood obesity as well as prevention guidelines developed by the American Academy of Pediatrics (AAP). NPs working in family practice or general pediatric practice settings were not consistently using the BMI-for-age index to screen for childhood obesity, as recommended by the AAP. However, they were teaching parents to promote healthy food choices and physical activity in their families. PNPs and FNPs working in a pediatric practice setting and NPs who were aware of prevention guidelines were more likely to perform several prevention strategies than FNPs working in a family practice setting and those who were unaware of guidelines. Major barriers to implementing childhood obesity prevention strategies included parental attitudes, the American lifestyle, and lack of resources for both the NP and the family. The main resources NPs used in preventing childhood obesity were a dietician, journal articles, and Web sites. Although the majority of the NPs in this study reported being aware of childhood obesity prevention guidelines (73.7%), most were not consistently using BMI for age or monitoring children at increased risk for obesity. Because childhood obesity is escalating at such a rapid rate, it is critical that NPs working in family practice and pediatric practice settings take the necessary steps to help curtail obesity in childhood, including calculating BMI for age, targeting children at risk, and helping families develop healthy nutrition and physical activity habits. In addition to proper health supervision of children, NPs also need to be advocates in their communities to overcome barriers to childhood obesity prevention.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18365677" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8a1728bf21015fb624663c57eafad339" rel="nofollow" data-download="{&quot;attachment_id&quot;:42174574,&quot;asset_id&quot;:18365677,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42174574/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38357256" href="https://independent.academia.edu/LoneLarsen2">Lone Larsen</a><script data-card-contents-for-user="38357256" type="text/json">{"id":38357256,"first_name":"Lone","last_name":"Larsen","domain_name":"independent","page_name":"LoneLarsen2","display_name":"Lone Larsen","profile_url":"https://independent.academia.edu/LoneLarsen2?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_18365677 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18365677"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18365677, container: ".js-paper-rank-work_18365677", }); 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A convenience sample of 99 family NPs (FNPs) and pediatric NPs (PNPs) from the Intermountain area was used. Participants completed a questionnaire based on documented risk factors for childhood obesity as well as prevention guidelines developed by the American Academy of Pediatrics (AAP). NPs working in family practice or general pediatric practice settings were not consistently using the BMI-for-age index to screen for childhood obesity, as recommended by the AAP. However, they were teaching parents to promote healthy food choices and physical activity in their families. PNPs and FNPs working in a pediatric practice setting and NPs who were aware of prevention guidelines were more likely to perform several prevention strategies than FNPs working in a family practice setting and those who were unaware of guidelines. Major barriers to implementing childhood obesity prevention strategies included parental attitudes, the American lifestyle, and lack of resources for both the NP and the family. The main resources NPs used in preventing childhood obesity were a dietician, journal articles, and Web sites. Although the majority of the NPs in this study reported being aware of childhood obesity prevention guidelines (73.7%), most were not consistently using BMI for age or monitoring children at increased risk for obesity. Because childhood obesity is escalating at such a rapid rate, it is critical that NPs working in family practice and pediatric practice settings take the necessary steps to help curtail obesity in childhood, including calculating BMI for age, targeting children at risk, and helping families develop healthy nutrition and physical activity habits. 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data-has-card-for-ri="29154" href="https://www.academia.edu/Documents/in/Cardiovascular_Risk">Cardiovascular Risk</a>,&nbsp;<script data-card-contents-for-ri="29154" type="text/json">{"id":29154,"name":"Cardiovascular Risk","url":"https://www.academia.edu/Documents/in/Cardiovascular_Risk?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1292329" href="https://www.academia.edu/Documents/in/Primary_Prevention">Primary Prevention</a><script data-card-contents-for-ri="1292329" type="text/json">{"id":1292329,"name":"Primary Prevention","url":"https://www.academia.edu/Documents/in/Primary_Prevention?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8850857]'), work: {"id":8850857,"title":"La valutazione del rischio cardiovascolare globale assoluto: il punteggio individuale del Progetto 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data-work_id="11982051" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11982051/Addressing_the_Needs_of_Children_of_Parents_With_a_Mental_Illness_Current_Approaches">Addressing the Needs of Children of Parents With a Mental Illness: Current Approaches</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11982051" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="87fec7c6377f7235bdb92388d42ff548" 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href="https://independent.academia.edu/KimFoster5">Kim Foster</a><script data-card-contents-for-user="42562774" type="text/json">{"id":42562774,"first_name":"Kim","last_name":"Foster","domain_name":"independent","page_name":"KimFoster5","display_name":"Kim Foster","profile_url":"https://independent.academia.edu/KimFoster5?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-11982051">+1</span><div class="hidden js-additional-users-11982051"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://cqu1.academia.edu/MargaretMcAllister">Margaret McAllister</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-11982051'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return 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class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-13274503">+1</span><div class="hidden js-additional-users-13274503"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/BHouston1">B. 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The... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_58793572" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We propose a cycles-breaking conceptual framework to guide perinatal research, interventions, and clinical innovations that can prevent or disrupt intergenerational cycles of childhood maltreatment and psychiatric vulnerability. The framework is grounded in literature, clinical observations, team science collaboration, and empirical research from numerous disciplines and is specific to the childbearing year. Adoption of the framework has the potential to speed the progress of research on the social problems of intergenerational childhood maltreatment and psychiatric vulnerability.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/58793572" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="08ef3eaa6bf33f5729a85e7344b9d332" rel="nofollow" data-download="{&quot;attachment_id&quot;:73033445,&quot;asset_id&quot;:58793572,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/73033445/download_file?st=MTczMjQyNDQyMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34621531" href="https://buffalo.academia.edu/MickeySperlich">Mickey Sperlich</a><script data-card-contents-for-user="34621531" type="text/json">{"id":34621531,"first_name":"Mickey","last_name":"Sperlich","domain_name":"buffalo","page_name":"MickeySperlich","display_name":"Mickey Sperlich","profile_url":"https://buffalo.academia.edu/MickeySperlich?f_ri=1292329","photo":"https://0.academia-photos.com/34621531/10112281/11282772/s65_mickey.sperlich.jpg_oh_628e975b767be2b7a2b1318771e0940c_oe_566153a8___gda___1449202064_0dfd5e46fe1c4778b901751c10bf15a7"}</script></span></span></li><li class="js-paper-rank-work_58793572 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="58793572"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 58793572, container: ".js-paper-rank-work_58793572", }); 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href="https://umassmed.academia.edu/suzannecashman">suzanne cashman</a><script data-card-contents-for-user="103482" type="text/json">{"id":103482,"first_name":"suzanne","last_name":"cashman","domain_name":"umassmed","page_name":"suzannecashman","display_name":"suzanne cashman","profile_url":"https://umassmed.academia.edu/suzannecashman?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-18113095">+1</span><div class="hidden js-additional-users-18113095"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/DavidGarr">David Garr</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-18113095'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return 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href="https://www.academia.edu/47581535/Pakistan_country_profile_of_cancer_and_cancer_control_1995_2004">Pakistan--country profile of cancer and cancer control 1995-2004</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/47581535" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1896167d62f2ba2f418c6b2a8a27465e" rel="nofollow" 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itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31860638" href="https://independent.academia.edu/anaperez104">ana perez</a><script data-card-contents-for-user="31860638" type="text/json">{"id":31860638,"first_name":"ana","last_name":"perez","domain_name":"independent","page_name":"anaperez104","display_name":"ana perez","profile_url":"https://independent.academia.edu/anaperez104?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12790630 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12790630"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12790630, container: ".js-paper-rank-work_12790630", }); });</script></li><li class="js-percentile-work_12790630 InlineList-item 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href="https://www.academia.edu/5673379/Consensus_Statement_on_Chronic_and_Subacute_High_Altitude_Diseases">Consensus Statement on Chronic and Subacute High Altitude Diseases</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/5673379" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4c19f4c5d04ddc1c8f8b5d1175091db8" rel="nofollow" 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data-has-card-for-ri="12054" href="https://www.academia.edu/Documents/in/International_Cooperation">International Cooperation</a>,&nbsp;<script data-card-contents-for-ri="12054" type="text/json">{"id":12054,"name":"International Cooperation","url":"https://www.academia.edu/Documents/in/International_Cooperation?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="24837" href="https://www.academia.edu/Documents/in/Peer_Review">Peer Review</a>,&nbsp;<script data-card-contents-for-ri="24837" type="text/json">{"id":24837,"name":"Peer Review","url":"https://www.academia.edu/Documents/in/Peer_Review?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a><script data-card-contents-for-ri="64568" 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class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a>,&nbsp;<script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="93353" href="https://www.academia.edu/Documents/in/North_Carolina">North Carolina</a><script data-card-contents-for-ri="93353" type="text/json">{"id":93353,"name":"North Carolina","url":"https://www.academia.edu/Documents/in/North_Carolina?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17214557]'), work: {"id":17214557,"title":"Chronic kidney disease in North 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})();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18298613" data-work_id="18298613" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18298613/Bystander_education_training_for_campus_sexual_assault_prevention_an_initial_meta_analysis">Bystander education training for campus sexual assault prevention: an initial meta-analysis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The present meta-analysis evaluated the effectiveness of bystander education programs for preventing sexual assault in college communities. Undergraduates trained in bystander education for sexual assault were expected to report more... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_18298613" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The present meta-analysis evaluated the effectiveness of bystander education programs for preventing sexual assault in college communities. Undergraduates trained in bystander education for sexual assault were expected to report more favorable attitudes, behavioral proclivities, and actual behaviors relative to untrained controls. Data from 12 studies of college students (N = 2,926) were used to calculate 32 effect sizes. Results suggested moderate effects of bystander education on both bystander efficacy and intentions to help others at risk. Smaller but significant effects were observed regarding self-reported bystander helping behaviors, (lower) rape-supportive attitudes, and (lower) rape proclivity, but not perpetration. These results provide initial support for the effectiveness of in-person bystander education training. Nonetheless, future longitudinal research evaluating behavioral outcomes and sexual assault incidence is needed.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18298613" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="af923c835dee5788ba516b27197eff5e" rel="nofollow" data-download="{&quot;attachment_id&quot;:39980687,&quot;asset_id&quot;:18298613,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/39980687/download_file?st=MTczMjQyNDQyMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38281175" href="https://independent.academia.edu/JenniferKatz2">Jennifer Katz</a><script data-card-contents-for-user="38281175" type="text/json">{"id":38281175,"first_name":"Jennifer","last_name":"Katz","domain_name":"independent","page_name":"JenniferKatz2","display_name":"Jennifer Katz","profile_url":"https://independent.academia.edu/JenniferKatz2?f_ri=1292329","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_18298613 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18298613"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18298613, container: ".js-paper-rank-work_18298613", }); 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$(".js-view-count[data-work-id=18298613]").text(description); $(".js-view-count-work_18298613").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_18298613").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="18298613"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">18</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="189" href="https://www.academia.edu/Documents/in/Criminology">Criminology</a>,&nbsp;<script data-card-contents-for-ri="189" type="text/json">{"id":189,"name":"Criminology","url":"https://www.academia.edu/Documents/in/Criminology?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1697" href="https://www.academia.edu/Documents/in/Violence">Violence</a>,&nbsp;<script data-card-contents-for-ri="1697" type="text/json">{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4802" href="https://www.academia.edu/Documents/in/Rape">Rape</a>,&nbsp;<script data-card-contents-for-ri="4802" type="text/json">{"id":4802,"name":"Rape","url":"https://www.academia.edu/Documents/in/Rape?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7428" href="https://www.academia.edu/Documents/in/Health_Education">Health Education</a><script data-card-contents-for-ri="7428" type="text/json">{"id":7428,"name":"Health Education","url":"https://www.academia.edu/Documents/in/Health_Education?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=18298613]'), work: {"id":18298613,"title":"Bystander education training for campus sexual assault prevention: an initial meta-analysis","created_at":"2015-11-13T12:25:33.721-08:00","url":"https://www.academia.edu/18298613/Bystander_education_training_for_campus_sexual_assault_prevention_an_initial_meta_analysis?f_ri=1292329","dom_id":"work_18298613","summary":"The present meta-analysis evaluated the effectiveness of bystander education programs for preventing sexual assault in college communities. Undergraduates trained in bystander education for sexual assault were expected to report more favorable attitudes, behavioral proclivities, and actual behaviors relative to untrained controls. Data from 12 studies of college students (N = 2,926) were used to calculate 32 effect sizes. Results suggested moderate effects of bystander education on both bystander efficacy and intentions to help others at risk. Smaller but significant effects were observed regarding self-reported bystander helping behaviors, (lower) rape-supportive attitudes, and (lower) rape proclivity, but not perpetration. These results provide initial support for the effectiveness of in-person bystander education training. Nonetheless, future longitudinal research evaluating behavioral outcomes and sexual assault incidence is needed.","downloadable_attachments":[{"id":39980687,"asset_id":18298613,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38281175,"first_name":"Jennifer","last_name":"Katz","domain_name":"independent","page_name":"JenniferKatz2","display_name":"Jennifer Katz","profile_url":"https://independent.academia.edu/JenniferKatz2?f_ri=1292329","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":189,"name":"Criminology","url":"https://www.academia.edu/Documents/in/Criminology?f_ri=1292329","nofollow":false},{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=1292329","nofollow":false},{"id":4802,"name":"Rape","url":"https://www.academia.edu/Documents/in/Rape?f_ri=1292329","nofollow":false},{"id":7428,"name":"Health Education","url":"https://www.academia.edu/Documents/in/Health_Education?f_ri=1292329","nofollow":false},{"id":11015,"name":"Social Support","url":"https://www.academia.edu/Documents/in/Social_Support?f_ri=1292329"},{"id":40023,"name":"Social Responsibility","url":"https://www.academia.edu/Documents/in/Social_Responsibility?f_ri=1292329"},{"id":40475,"name":"Helping Behavior","url":"https://www.academia.edu/Documents/in/Helping_Behavior?f_ri=1292329"},{"id":56132,"name":"Students","url":"https://www.academia.edu/Documents/in/Students?f_ri=1292329"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=1292329"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=1292329"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male?f_ri=1292329"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=1292329"},{"id":172809,"name":"Interpersonal Relations","url":"https://www.academia.edu/Documents/in/Interpersonal_Relations?f_ri=1292329"},{"id":274835,"name":"Male Domestic Violence Victims","url":"https://www.academia.edu/Documents/in/Male_Domestic_Violence_Victims?f_ri=1292329"},{"id":284849,"name":"Peer group","url":"https://www.academia.edu/Documents/in/Peer_group?f_ri=1292329"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=1292329"},{"id":1034181,"name":"Cross Sectional Studies","url":"https://www.academia.edu/Documents/in/Cross_Sectional_Studies?f_ri=1292329"},{"id":1292329,"name":"Primary Prevention","url":"https://www.academia.edu/Documents/in/Primary_Prevention?f_ri=1292329"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13804329" data-work_id="13804329" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13804329/Prevalence_of_prehypertension_and_associated_cardiovascular_risk_profiles_among_prediabetic_Omani_adults">Prevalence of prehypertension and associated cardiovascular risk profiles among prediabetic Omani adults</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13804329" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7a7a5ae81fd456def10baebc78ab0947" rel="nofollow" data-download="{&quot;attachment_id&quot;:44932646,&quot;asset_id&quot;:13804329,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44932646/download_file?st=MTczMjQyNDQyMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32905923" href="https://squ.academia.edu/ShyamSundarGanguly">Shyam Sundar. Ganguly</a><script data-card-contents-for-user="32905923" type="text/json">{"id":32905923,"first_name":"Shyam Sundar.","last_name":"Ganguly","domain_name":"squ","page_name":"ShyamSundarGanguly","display_name":"Shyam Sundar. 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Approximately one in four women are raped in their adult lifetime, which causes severe psychological distress and long-term physical... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_2456473" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">During the past 20 years, researchers have documented the widespread problem of rape in American society. Approximately one in four women are raped in their adult lifetime, which causes severe psychological distress and long-term physical health problems. The impact of sexual assault extends far beyond rape survivors as their family, friends, and significant others are also negatively affected. Moreover, those who help rape victims, such as rape victim advocates, therapists, as well as sexual assault researchers, can experience vicarious trauma. Future research and advocacy should focus on improving the community response to rape and the prevention of sexual assault.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/2456473" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3e85886a22d821cfa180ac24e005a1c8" rel="nofollow" data-download="{&quot;attachment_id&quot;:59186946,&quot;asset_id&quot;:2456473,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/59186946/download_file?st=MTczMjQyNDQyMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3201554" href="https://uml.academia.edu/SharonWasco">Sharon M Wasco</a><script data-card-contents-for-user="3201554" type="text/json">{"id":3201554,"first_name":"Sharon","last_name":"Wasco","domain_name":"uml","page_name":"SharonWasco","display_name":"Sharon M Wasco","profile_url":"https://uml.academia.edu/SharonWasco?f_ri=1292329","photo":"https://0.academia-photos.com/3201554/2975823/30822678/s65_sharon.wasco.jpeg"}</script></span></span></li><li class="js-paper-rank-work_2456473 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="2456473"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 2456473, container: ".js-paper-rank-work_2456473", }); });</script></li><li class="js-percentile-work_2456473 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 2456473; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_2456473"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_2456473 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="2456473"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 2456473; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=2456473]").text(description); $(".js-view-count-work_2456473").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_2456473").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="2456473"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">24</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="189" href="https://www.academia.edu/Documents/in/Criminology">Criminology</a>,&nbsp;<script data-card-contents-for-ri="189" type="text/json">{"id":189,"name":"Criminology","url":"https://www.academia.edu/Documents/in/Criminology?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="221" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>,&nbsp;<script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="2066" href="https://www.academia.edu/Documents/in/Research_Design">Research Design</a>,&nbsp;<script data-card-contents-for-ri="2066" type="text/json">{"id":2066,"name":"Research Design","url":"https://www.academia.edu/Documents/in/Research_Design?f_ri=1292329","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4802" href="https://www.academia.edu/Documents/in/Rape">Rape</a><script data-card-contents-for-ri="4802" type="text/json">{"id":4802,"name":"Rape","url":"https://www.academia.edu/Documents/in/Rape?f_ri=1292329","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=2456473]'), work: {"id":2456473,"title":"Understanding Rape and Sexual Assault20 Years of Progress and Future Directions","created_at":"2013-01-24T06:53:06.965-08:00","url":"https://www.academia.edu/2456473/Understanding_Rape_and_Sexual_Assault20_Years_of_Progress_and_Future_Directions?f_ri=1292329","dom_id":"work_2456473","summary":"During the past 20 years, researchers have documented the widespread problem of rape in American society. Approximately one in four women are raped in their adult lifetime, which causes severe psychological distress and long-term physical health problems. The impact of sexual assault extends far beyond rape survivors as their family, friends, and significant others are also negatively affected. Moreover, those who help rape victims, such as rape victim advocates, therapists, as well as sexual assault researchers, can experience vicarious trauma. 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