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(PDF) Evaluation of the anticancer potential of six herbs against a hepatoma cell line | Sahapat Barusrux - Academia.edu

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"https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F45461336%2FEvaluation_of_the_anticancer_potential_of_six_herbs_against_a_hepatoma_cell_line%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":65966899,"identifier":"Attachment_65966899","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":45461336,"created_at":"2021-03-10T17:45:46.490-08:00","from_world_paper_id":166990382,"updated_at":"2024-11-13T21:19:17.971-08:00","_data":{"publisher":"Springer Nature","grobid_abstract":"Background: Six herbs in the Plant Genetics Conservation Project that have been used as complementary medicines were chosen on the basis of their medicinal value, namely Terminalia mucronata, Diospyros winitii, Bridelia insulana, Artabotrys harmandii, Terminallia triptera, and Croton oblongifolius. This study aims to evaluate the potential anticancer activity of 50% ethanol-water extracts of these six herbs. Methods: Fifty percent ethanol-water crude extracts of the six herbs were prepared. The cytotoxicity of the herbal extracts relative to that of melphalan was evaluated using a hepatoma cell line (HepG2), and examined by neutral red assays and apoptosis induction by gel electrophoresis and flow cytometry after 24 h.","publication_date":"2012,,","publication_name":"Chinese Medicine","grobid_abstract_attachment_id":"65966899"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Evaluation of the anticancer potential of six herbs against a hepatoma cell line","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [12754608]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;swp-splash-paper-cover&quot;,&quot;attachmentId&quot;:65966899,&quot;attachmentType&quot;:&quot;pdf&quot;}"><img alt="First page of “Evaluation of the anticancer potential of six herbs against a hepatoma cell line”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/65966899/mini_magick20210310-2426-7eci2y.png?1615429912" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Evaluation of the anticancer potential of six herbs against a hepatoma cell line</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="12754608" href="https://independent.academia.edu/SahapatBarusrux"><img alt="Profile image of Sahapat Barusrux" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/12754608/94935755/83907845/s65_sahapat.barusrux.jpg" />Sahapat Barusrux</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2012, Chinese Medicine</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">7 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 45461336; 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Plants were fractionated using ethanol, methanol, chloroform, n-hexane, distilled water, and butanol. The antiproliferative activity was measured by MTT assay. TLC was used to identify active fractions. The apoptotic activity of active fractions was determined using TUNEL colorimetric assay. 20 of these extracts demonstrated significant antiproliferative activity against one or more of the cell lines. These extracts were prepared from Ononis hirta, Inula viscosa, Salvia pinardi, Verbascum sinaiticum and Ononis sicula. Methanol fractions of Ononis hirta (aerial parts) and Inula viscosa (flowers) were the most active fractions against MCF-7 cells with IC(50) of 27.96 and 15.78 Îg/ml respectively and they were less toxic against other cell lines. Other extracts showed lower activity against cancer cell li...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Antiproliferative activity of plant extracts used against cancer in traditional medicine&quot;,&quot;attachmentId&quot;:85785926,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/78573751/Antiproliferative_activity_of_plant_extracts_used_against_cancer_in_traditional_medicine&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/78573751/Antiproliferative_activity_of_plant_extracts_used_against_cancer_in_traditional_medicine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="106281123" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/106281123/ETHNOPHARMACOLOGICAL_EVALUATION_OF_MEDICINAL_PLANTS_FOR_CYTOTOXICITY_AGAINST_VARIOUS_CANCER_CELL_LINES_Original_Article">ETHNOPHARMACOLOGICAL EVALUATION OF MEDICINAL PLANTS FOR CYTOTOXICITY AGAINST VARIOUS CANCER CELL LINES Original Article</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="265496504" href="https://independent.academia.edu/InternationalJournalofPharmacyandPharmaceuticalSciencesIJPPS">International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Pharmacy and Pharmaceutical Sciences, 2017</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective: To evaluate the cytotoxic potential of leaves and seeds of Hibiscus sabdariffa L., fruit juice of Phyllanthus emblica, rhizomes of Dryopteris cochleata and flowers of Caesalpinia decapetala (Roth) Alston along with the chemical profiling of the most toxic extract through Gas-mass spectroscopy-MS technique. Methods: The hydroalcoholic extract of the selected crude drugs was prepared by maceration method and the extracts were undergone through phytochemical analysis. The cytotoxic activity of the hydroalcoholic extract was performed against four cancer cell lines i.e. liver (HepG2), breast (MCF7), prostate (PC-3) and leukemia (HL60) using sulphorhodamine B assay. The hydroalcoholic extract of Caesalpinia decapetala flowers was profiled through using gas mass spectroscopy. Results: The results confirmed that Phyllanthus emblica inhibited HL60 cancer cells at the dose of 35.6 µg/ml and show dose-dependent growth inhibition. The flowers of Caesalpinia decapetala inhibited nearly fifty percent of HL60 cancer cells at very low dose i. e 10 µg/ml. The analysis of Caesalpinia decapetala flowers shows the presence of diterpenoid furanolactones, bufadienolides, polycyclic enones, and androsterone. Conclusion: The fruit juice of Phyllanthus emblica and flowers of Caesalpinia decapetala showed good inhibitory activity against HL60 cancer cell line. The use of Phyllanthus emblica in herbal medicine is justified. The data obtained impelled to further assess the in vivo efficacy of Caesalpinia decapetala flowers for anticancer activity.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;ETHNOPHARMACOLOGICAL EVALUATION OF MEDICINAL PLANTS FOR CYTOTOXICITY AGAINST VARIOUS CANCER CELL LINES Original Article&quot;,&quot;attachmentId&quot;:105520077,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/106281123/ETHNOPHARMACOLOGICAL_EVALUATION_OF_MEDICINAL_PLANTS_FOR_CYTOTOXICITY_AGAINST_VARIOUS_CANCER_CELL_LINES_Original_Article&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/106281123/ETHNOPHARMACOLOGICAL_EVALUATION_OF_MEDICINAL_PLANTS_FOR_CYTOTOXICITY_AGAINST_VARIOUS_CANCER_CELL_LINES_Original_Article"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="111662506" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/111662506/Effects_of_Some_Natural_Extracts_on_the_Apoptotic_Process_in_Rat_Tumoral_Cells_Assessed_by_Flow_Cytometry">Effects of Some Natural Extracts, on the Apoptotic Process, in Rat Tumoral Cells, Assessed by Flow Cytometry</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37819494" href="https://virology.academia.edu/CarmenDiaconu">Carmen C Diaconu</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2008</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Effects of Some Natural Extracts, on the Apoptotic Process, in Rat Tumoral Cells, Assessed by Flow Cytometry&quot;,&quot;attachmentId&quot;:109133825,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/111662506/Effects_of_Some_Natural_Extracts_on_the_Apoptotic_Process_in_Rat_Tumoral_Cells_Assessed_by_Flow_Cytometry&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/111662506/Effects_of_Some_Natural_Extracts_on_the_Apoptotic_Process_in_Rat_Tumoral_Cells_Assessed_by_Flow_Cytometry"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="45461335" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/45461335/Cytotoxic_and_apoptotic_effects_of_six_herbal_plants_against_the_human_hepatocarcinoma_HepG2_cell_line">Cytotoxic and apoptotic effects of six herbal plants against the human hepatocarcinoma (HepG2) cell line</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="12754608" href="https://independent.academia.edu/SahapatBarusrux">Sahapat Barusrux</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Chinese Medicine, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Cytotoxic and apoptotic effects of six herbal plants against the human hepatocarcinoma (HepG2) cell line&quot;,&quot;attachmentId&quot;:65966909,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/45461335/Cytotoxic_and_apoptotic_effects_of_six_herbal_plants_against_the_human_hepatocarcinoma_HepG2_cell_line&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/45461335/Cytotoxic_and_apoptotic_effects_of_six_herbal_plants_against_the_human_hepatocarcinoma_HepG2_cell_line"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="104797733" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/104797733/Anticancer_Activity_of_Ethnopharmacological_Plants_of_Golestan_Province_Iran_against_AGS_HT_29_and_KYSE_30_Cell_Lines_through_Promoting_the_Apoptosis_and_Immunomodulatory_Effects">Anticancer Activity of Ethnopharmacological Plants of Golestan Province/Iran against AGS, HT-29 and KYSE-30 Cell Lines through Promoting the Apoptosis and Immunomodulatory Effects</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="230480333" href="https://independent.academia.edu/ayeshehenayati">ayesheh enayati</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Iranian Journal of Pharmaceutical Research : IJPR, 2021</p><p class="ds-related-work--abstract ds2-5-body-sm">The anticancer and immunomodulatory effects of medicinal plants from Golestan province, as a promising source of cancer therapy against gastrointestinal cancer cell lines, were investigated in this study. The ethanolic root/aerial part extracts of 9 medicinal plants were screened for their cytotoxicity against normal mouse fibroblast cells (L-929) and three human cancer cell lines including gastric adenocarcinoma (AGS), colorectal adenocarcinoma (HT-29), and esophagus adenocarcinoma (KYSE-30) by performing MTT assay to determine the IC50 of the extracts. The in-vitro antioxidant activity, total phenolic (TPC), and total flavonoid content (TFC) of extracts was evaluated. Flow cytometry and Real-Time PCR were used for apoptosis assay and evaluation of expression of some genes involved in cell signaling; TLR-4, AKT, ERK1/2, and NFκB. Out of the 9 plant extracts screened, Arctiumlappa root (ALR), showed the most potent cytotoxicity against AGS, KYSE-30, and HT-29 cells with IC50 values ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Anticancer Activity of Ethnopharmacological Plants of Golestan Province/Iran against AGS, HT-29 and KYSE-30 Cell Lines through Promoting the Apoptosis and Immunomodulatory Effects&quot;,&quot;attachmentId&quot;:104430874,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/104797733/Anticancer_Activity_of_Ethnopharmacological_Plants_of_Golestan_Province_Iran_against_AGS_HT_29_and_KYSE_30_Cell_Lines_through_Promoting_the_Apoptosis_and_Immunomodulatory_Effects&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/104797733/Anticancer_Activity_of_Ethnopharmacological_Plants_of_Golestan_Province_Iran_against_AGS_HT_29_and_KYSE_30_Cell_Lines_through_Promoting_the_Apoptosis_and_Immunomodulatory_Effects"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="50404538" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/50404538/In_vitro_anticancer_activity_of_some_plants_used_in_Moroccan_traditional_medicine">In vitro anticancer activity of some plants used in Moroccan traditional medicine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="166527732" href="https://independent.academia.edu/abdeljlilDAOUDI">abdeljlil DAOUDI</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Medicinal Plants Research, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;In vitro anticancer activity of some plants used in Moroccan traditional medicine&quot;,&quot;attachmentId&quot;:68405667,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/50404538/In_vitro_anticancer_activity_of_some_plants_used_in_Moroccan_traditional_medicine&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/50404538/In_vitro_anticancer_activity_of_some_plants_used_in_Moroccan_traditional_medicine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="29410216" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/29410216/Journal_of_Medicinal_Plants_Research_In_vitro_anticancer_activity_of_some_plants_used_in_Moroccan_traditional_medicine">Journal of Medicinal Plants Research In vitro anticancer activity of some plants used in Moroccan traditional medicine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="51082570" href="https://on.academia.edu/lotfiAARAB">lotfi AARAB</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Over time, cancer remains a world public health problem. The use of traditional medicine as alternative treatments of cancer was recognized in 1950s by the US National Cancer Institute (NCI) under the leadership of the late Dr. Jonathan Hartwell. In this context, we are interested to search for bioactive natural substances for cancer therapy used in Moroccan traditional medicine. Based on ethnopharmacological study, we selected four plants with an important therapy against cancer in Moroccan traditional medicine; these are Aristolochia longa (L), Citrullus colocynthis (L), Piper cubeba (L) and Delphinium Staphisagria (L). In the pharmacological study, we evaluated the antiproliferative activity of selected Moroccan plants on five different cancer cell lines namely MCF7, HT29, N2A, H5-6 and VCREMS using 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay at a dose of 500 µg/ml; lyophilized extracts after 24 h of treatment showed that two plants possess significant cytotoxic activity against cancer cell lines, such as MCF7, HT29, N2A, H5-6 and VCREMS. P. cubeba (L) extract showed the inhibition of 98.64 and 91.59% against MCF7 lines and HT29 cell lines, and for C. colocynthis (L), 91.84 and 85.58%, respectively. C. colocynthis (L) showed a dose-dependent effect on MCF7 and HT29 cell lines with an IC 50 of 22.0 and 32.5 µg/ml, respectively. This cytotoxicity is induced probably by apoptosis.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Journal of Medicinal Plants Research In vitro anticancer activity of some plants used in Moroccan traditional medicine&quot;,&quot;attachmentId&quot;:49852495,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/29410216/Journal_of_Medicinal_Plants_Research_In_vitro_anticancer_activity_of_some_plants_used_in_Moroccan_traditional_medicine&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/29410216/Journal_of_Medicinal_Plants_Research_In_vitro_anticancer_activity_of_some_plants_used_in_Moroccan_traditional_medicine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="112916343" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/112916343/A_Review_of_Medicinal_Plants_Effective_in_the_Treatment_or_Apoptosis_of_Cancer_Cells">A Review of Medicinal Plants Effective in the Treatment or Apoptosis of Cancer Cells</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="285311046" href="https://independent.academia.edu/Niloufarkarami3">Niloufar karami</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Cancer Press, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;A Review of Medicinal Plants Effective in the Treatment or Apoptosis of Cancer Cells&quot;,&quot;attachmentId&quot;:110012308,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/112916343/A_Review_of_Medicinal_Plants_Effective_in_the_Treatment_or_Apoptosis_of_Cancer_Cells&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/112916343/A_Review_of_Medicinal_Plants_Effective_in_the_Treatment_or_Apoptosis_of_Cancer_Cells"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="100384271" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/100384271/Evaluation_of_some_plant_extracts_for_standardization_and_anticancer_activity">Evaluation of some plant extracts for standardization and anticancer activity</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="128356583" href="https://independent.academia.edu/DrMMPadhi">Dr. M.M. Padhi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Indian journal of traditional knowledge</p><p class="ds-related-work--abstract ds2-5-body-sm">In recent times, the trend in cancer research is shifting towards identifying new medicines from natural resources for management of cancer. Medicinal plants such as Sthauneyaka (Taxus baccata L.) and compound formulations like Triphala ghrita, Khadirarista, Madhusnuhi rasayana, Maha triphaladya ghrita, Panchatikta guggulu ghrita are indicated in the Ayurvedic texts for management of cancer/ tumour. The anti-proliferative activities of hydro-alcoholic extracts of some standardized plant materials were screened against a panel of 14 human cancer cell lines representing different tissues (lung, pancreas, colon, cervix, oral, bladder, prostate, breast, leukaemia, etc.) through Sulforhodamine-B (SRB) assay. The findings revealed that Cedrus deodara (Roxb.) ex Lamb. and Berberis aristata (Roxb.) ex DC. have maximum anticancer activity against 3 cell lines while Withania somnifera Dunal. showed activity against two cell lines. In addition to these, Picrorhiza kurroa Royle ex Benth. and Pi...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Evaluation of some plant extracts for standardization and anticancer activity&quot;,&quot;attachmentId&quot;:101223232,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/100384271/Evaluation_of_some_plant_extracts_for_standardization_and_anticancer_activity&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/100384271/Evaluation_of_some_plant_extracts_for_standardization_and_anticancer_activity"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="91644635" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/91644635/Anticancer_activity_of_plant_leaves_extract_collected_from_a_tribal_region_of_India">Anticancer activity of plant leaves extract collected from a tribal region of India</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="247289996" href="https://independent.academia.edu/devpandey57">dev pandey</a></div><p class="ds-related-work--metadata ds2-5-body-xs">3 Biotech, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Anticancer activity of plant leaves extract collected from a tribal region of India&quot;,&quot;attachmentId&quot;:94874062,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/91644635/Anticancer_activity_of_plant_leaves_extract_collected_from_a_tribal_region_of_India&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/91644635/Anticancer_activity_of_plant_leaves_extract_collected_from_a_tribal_region_of_India"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:65966899,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--sticky-ctas&quot;,&quot;attachmentId&quot;:65966899,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_65966899" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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