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Medicinal plants such as Sthauneyaka (Taxus baccata L.) and compound formulations like Triphala ghrita, Khadirarista, Madhusnuhi rasayana, Maha triphaladya ghrita, Panchatikta guggulu ghrita are indicated in the Ayurvedic texts for management of cancer/ tumour. The anti-proliferative activities of hydro-alcoholic extracts of some standardized plant materials were screened against a panel of 14 human cancer cell lines representing different tissues (lung, pancreas, colon, cervix, oral, bladder, prostate, breast, leukaemia, etc.) through Sulforhodamine-B (SRB) assay. The findings revealed that Cedrus deodara (Roxb.) ex Lamb. and Berberis aristata (Roxb.) ex DC. have maximum anticancer activity against 3 cell lines while Withania somnifera Dunal. showed activity against two cell lines. In addition to these, Picrorhiza kurroa Royle ex Benth. and Pi...","author":[{"@context":"https://schema.org","@type":"Person","name":"Dr. M.M. Padhi"}],"contributor":[],"dateCreated":"2023-04-18","dateModified":null,"datePublished":null,"headline":"Evaluation of some plant extracts for standardization and anticancer activity","inLanguage":"en","keywords":["Traditional Medicine","Biology","Medicinal Plants","Standardization","Withania Somnifera","Anticancer activity","Indian Traditional Knowledge","Sulforhodamine B"],"locationCreated":null,"publication":"Indian journal of traditional knowledge","publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/100384271/Evaluation_of_some_plant_extracts_for_standardization_and_anticancer_activity","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/single_work_page/loswp-102fa537001ba4d8dcd921ad9bd56c474abc201906ea4843e7e7efe9dfbf561d.css" /><link rel="stylesheet" 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from natural resources for management of cancer. Medicinal plants such as Sthauneyaka (Taxus baccata L.) and compound formulations like Triphala ghrita, Khadirarista, Madhusnuhi rasayana, Maha triphaladya ghrita, Panchatikta guggulu ghrita are indicated in the Ayurvedic texts for management of cancer/ tumour. The anti-proliferative activities of hydro-alcoholic extracts of some standardized plant materials were screened against a panel of 14 human cancer cell lines representing different tissues (lung, pancreas, colon, cervix, oral, bladder, prostate, breast, leukaemia, etc.) through Sulforhodamine-B (SRB) assay. The findings revealed that Cedrus deodara (Roxb.) ex Lamb. and Berberis aristata (Roxb.) ex DC. have maximum anticancer activity against 3 cell lines while Withania somnifera Dunal. showed activity against two cell lines. In addition to these, Picrorhiza kurroa Royle ex Benth. and Pi...","publication_name":"Indian journal of traditional knowledge"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Evaluation of some plant extracts for standardization and anticancer activity","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [128356583]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":101223232,"attachmentType":"pdf"}"><img alt="First page of “Evaluation of some plant extracts for standardization and anticancer activity”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/101223232/mini_magick20230418-1-g0y04v.png?1681820754" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Evaluation of some plant extracts for standardization and anticancer activity</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="128356583" href="https://independent.academia.edu/DrMMPadhi"><img alt="Profile image of Dr. M.M. Padhi" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Dr. M.M. Padhi</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">Indian journal of traditional knowledge</p></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">In recent times, the trend in cancer research is shifting towards identifying new medicines from natural resources for management of cancer. Medicinal plants such as Sthauneyaka (Taxus baccata L.) and compound formulations like Triphala ghrita, Khadirarista, Madhusnuhi rasayana, Maha triphaladya ghrita, Panchatikta guggulu ghrita are indicated in the Ayurvedic texts for management of cancer/ tumour. The anti-proliferative activities of hydro-alcoholic extracts of some standardized plant materials were screened against a panel of 14 human cancer cell lines representing different tissues (lung, pancreas, colon, cervix, oral, bladder, prostate, breast, leukaemia, etc.) through Sulforhodamine-B (SRB) assay. The findings revealed that Cedrus deodara (Roxb.) ex Lamb. and Berberis aristata (Roxb.) ex DC. have maximum anticancer activity against 3 cell lines while Withania somnifera Dunal. showed activity against two cell lines. In addition to these, Picrorhiza kurroa Royle ex Benth. and Pi...</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":101223232,"attachmentType":"pdf","workUrl":"https://www.academia.edu/100384271/Evaluation_of_some_plant_extracts_for_standardization_and_anticancer_activity"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":101223232,"attachmentType":"pdf","workUrl":"https://www.academia.edu/100384271/Evaluation_of_some_plant_extracts_for_standardization_and_anticancer_activity"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="101223232" data-landing_url="https://www.academia.edu/100384271/Evaluation_of_some_plant_extracts_for_standardization_and_anticancer_activity" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="117208672" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/117208672/Evaluation_of_anticancer_activities_of_selected_medicinal_plants_from_Ganga_Choti_lesser_Himalaya_Bagh_Azad_Kashmir">Evaluation of anticancer activities of selected medicinal plants from Ganga Choti, lesser Himalaya, Bagh, Azad Kashmir</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="59701888" href="https://uaar.academia.edu/RQureshi">Rahmatullah Qureshi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pakistan Journal of Botany</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Evaluation of anticancer activities of selected medicinal plants from Ganga Choti, lesser Himalaya, Bagh, Azad Kashmir","attachmentId":113126483,"attachmentType":"pdf","work_url":"https://www.academia.edu/117208672/Evaluation_of_anticancer_activities_of_selected_medicinal_plants_from_Ganga_Choti_lesser_Himalaya_Bagh_Azad_Kashmir","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/117208672/Evaluation_of_anticancer_activities_of_selected_medicinal_plants_from_Ganga_Choti_lesser_Himalaya_Bagh_Azad_Kashmir"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="95058594" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/95058594/Anticancer_activity_of_Medicinal_plant_extract_A_re_view">Anticancer activity of Medicinal plant extract-A re view</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="13713277" href="https://independent.academia.edu/SavitaDixit">Savita Dixit</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2010</p><p class="ds-related-work--abstract ds2-5-body-sm">Traditional medicine has a long history of serving peoples all over the world. India is without doubt a herbal hub. Medicin al plants that are native to India and their use in various traditiona l systems of medicine are indeed awe-inspiring. The ethnobotany and ubiquitous plants provide a rich resource for Natural drug research a nd development. In recent years, the use of traditional medicine infor mation on plant research received considerable interest. The medici nal plants contain several phytochemicals such as vitamins, carotenoid s, terpenoids, flavonoids, polyphenols, alkaloids, tannins, saponi ns, enzymes, minerals etc. These phytochemicals possess antioxid ant activities, which, prevent or can be used in the treatment of m any diseases, including cancer. There are the several medicinal p lants all over the world, including India, which are being used tradit ionally for the prevention and treatment of cancer. The present pap er is a comprehensive review of different literat...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Anticancer activity of Medicinal plant extract-A re view","attachmentId":97345401,"attachmentType":"pdf","work_url":"https://www.academia.edu/95058594/Anticancer_activity_of_Medicinal_plant_extract_A_re_view","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/95058594/Anticancer_activity_of_Medicinal_plant_extract_A_re_view"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="44398237" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/44398237/Screening_of_Selected_Ethno_Medicinal_Plants_for_Anti_Cancer_Activity">Screening of Selected Ethno-Medicinal Plants for Anti-Cancer Activity</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="13473331" href="https://independent.academia.edu/KevinNelson2">Horizon Research Publishing(HRPUB) Kevin Nelson</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Advances in Zoology and Botany, 2020</p><p class="ds-related-work--abstract ds2-5-body-sm">Cancer is an epidemic worldwide. As per the report of the National Centre for Health Statistics in 2019, approximately 606,880 patients were died due to cancer and 1,762,450 new cases were detected. To overcome this scenario, worldwide research is going on to combat this disease. Among these, treatment of cancer through plant phytochemical has attended much prominence in the last few decades. Phytochemicals are produced by plants for their defense mechanism. However, these can also be used to treat many deadly diseases, among them cancer is most common. In the present study, we selected three Ethno-medicinal plants namely Careya arborea (leaf), Ficus religiosa (leaf) and Amorphophallus campanulatus (tuber) to evaluate their efficacy against A549 human lung cancer cells. MTT assay is widely used to assess cell viability. Human lung adenocarcinoma cell lines were purchased from NCCS, Pune and maintained in the laboratory under all standard conditions. Cells were grown, using ready to use media containing 4.5 grams of glucose, L-glutamine and sodium pyruvate. Growth factors were made available to the cells through the fetal bovine serum. We treated the cells with different concentrations of methanol and distilled water extracts of the selected plants and investigate the cell viability using a statistical test. We found varied significant differences between control cells and the cells treated with plant extracts.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Screening of Selected Ethno-Medicinal Plants for Anti-Cancer Activity","attachmentId":64805806,"attachmentType":"pdf","work_url":"https://www.academia.edu/44398237/Screening_of_Selected_Ethno_Medicinal_Plants_for_Anti_Cancer_Activity","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/44398237/Screening_of_Selected_Ethno_Medicinal_Plants_for_Anti_Cancer_Activity"><span class="ds2-5-text-link__content">View PDF</span><span 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data-entity-id="95302683" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/95302683/Traditional_medicinal_plants_as_anticancer_agents_from_Chhattishgarh_India_An_overview">Traditional medicinal plants as anticancer agents from Chhattishgarh, India: An overview</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="177844165" href="https://independent.academia.edu/RiteshJainTBTBilaspur">Ritesh Jain TBT, Bilaspur</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Phytomedicine, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Traditional medicinal plants as anticancer agents from Chhattishgarh, India: An overview","attachmentId":97521737,"attachmentType":"pdf","work_url":"https://www.academia.edu/95302683/Traditional_medicinal_plants_as_anticancer_agents_from_Chhattishgarh_India_An_overview","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/95302683/Traditional_medicinal_plants_as_anticancer_agents_from_Chhattishgarh_India_An_overview"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="37589136" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/37589136/THERAPEUTIC_APPLICATIONS_OF_MEDICINAL_PLANTS_FOUND_IN_ODISHA_USED_FOR_THE_TREATMENT_OF_CANCER">THERAPEUTIC APPLICATIONS OF MEDICINAL PLANTS FOUND IN ODISHA, USED FOR THE TREATMENT OF CANCER</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36195876" href="https://cutm.academia.edu/DrGyanranjanMahalik">Gyanranjan Mahalik</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Zingiberofficinale, Alliumsativum, Brassicaoleracea var. botrytis, Brassicaoleraceae var. capitata, Daucuscarota are found in Odishawhich were usedfor the treatment of cancer.C.roseusis an evergreen herbaceous plant contain alkaloids such as vinblastine, vincristine, vinorelbine, vinflunine inhibit spread of breast, ovary and lung cancer and also induce apoptosis.W.somnifera contain active components like withaferin,withanolide, withanoside and withanone. Particularly withaferinfound in this plant, inhibit breast cancer. Compounds such as bacopaside E and bacopaside VII extracted from B.monnieri have effects on cancer cells in malignantglioma and breast cancer. The main active compound of C.longa is curcumin which inhibit regrowth of cancer stem cells and shows best effects on breast and stomach cancer. O. sanctum has a range of beneficial compounds such as eugenol, rosmarinic acid, carnosic acid and apigenin inhibits the development of new tumors and inducers cell death. Z.officinalecontains a pungent compound such as 6-shogaol,zingerone and paradols provide chemopreventive activity which prevents and slows the progression of tumor growth. Arginine, oligosaccharides,flavonoids and selenium areextracted from A.sativum reduce risk of stomach, colon and breast cancer.B.oleraceae var.botrytis contains fiber, vitamin B and C, carotenoids, glucosinolates, isothiocyanates promote the death of cancer cells while sparing healthy cells. B.oleraceae var. capitatacontain antioxidants like vitamin A and C and phytonutrientssuch as thiocyanate, lutein, zeaxanthin, isothiocyanates, sulforaphane protect against breast, colon and prostate cancer. D.carota is a rich source of photochemicals and antioxidants like carotenoids, flavonoids,falcarinol prevents the cells from cancer. The above cheap medicinal herbs and their secondary metabolites are used effectively for the treatment of various types of cancer.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"THERAPEUTIC APPLICATIONS OF MEDICINAL PLANTS FOUND IN ODISHA, USED FOR THE TREATMENT OF CANCER","attachmentId":57569704,"attachmentType":"pdf","work_url":"https://www.academia.edu/37589136/THERAPEUTIC_APPLICATIONS_OF_MEDICINAL_PLANTS_FOUND_IN_ODISHA_USED_FOR_THE_TREATMENT_OF_CANCER","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/37589136/THERAPEUTIC_APPLICATIONS_OF_MEDICINAL_PLANTS_FOUND_IN_ODISHA_USED_FOR_THE_TREATMENT_OF_CANCER"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="68240420" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/68240420/Traditional_medicinal_plants_as_anticancer_agents_from_Chhattishgarh">Traditional medicinal plants as anticancer agents from Chhattishgarh</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="113977128" href="https://independent.academia.edu/SANMATIJAIN8">SANMATI JAIN</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2016</p><p class="ds-related-work--abstract ds2-5-body-sm">Email: sanmatijain72(at)yahoo.co.in reteshjain81(at)yahoo.com An attempt has been made to review some medicinal plants used for the prevention and treatment of cancer in Chhattisgarh. Information on the name of plants, family, parts used and method of preparation has been collected from Ethanobotanical literatures. Information collected has revealed 53 plants species that are used for treatment of cancer in Chhattisgarh. All these plants were further reviewed for scientific evidence, 33 plants out of 53 plants were found for possess anticancer, cytotoxic or antioxidant activity in various preclinical or clinical studies.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Traditional medicinal plants as anticancer agents from Chhattishgarh","attachmentId":78787147,"attachmentType":"pdf","work_url":"https://www.academia.edu/68240420/Traditional_medicinal_plants_as_anticancer_agents_from_Chhattishgarh","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/68240420/Traditional_medicinal_plants_as_anticancer_agents_from_Chhattishgarh"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="78521047" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/78521047/Anticancer_Activity_Evaluation_and_Some_Indian_Medicinal_Plants_from_Amarkantak_Mekal_Plateau_Madhya_Pradesh_India">Anticancer Activity Evaluation and Some Indian Medicinal Plants from Amarkantak Mekal Plateau Madhya Pradesh, India</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="218256298" href="https://independent.academia.edu/DrJitendraMalviya">Dr.Jitendra Malviya</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Current Microbiology and Applied Sciences, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Anticancer Activity Evaluation and Some Indian Medicinal Plants from Amarkantak Mekal Plateau Madhya Pradesh, India","attachmentId":85539944,"attachmentType":"pdf","work_url":"https://www.academia.edu/78521047/Anticancer_Activity_Evaluation_and_Some_Indian_Medicinal_Plants_from_Amarkantak_Mekal_Plateau_Madhya_Pradesh_India","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/78521047/Anticancer_Activity_Evaluation_and_Some_Indian_Medicinal_Plants_from_Amarkantak_Mekal_Plateau_Madhya_Pradesh_India"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="66736242" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/66736242/Study_of_the_anticancer_potential_of_Yemeni_plants_used_in_folk_medicine">Study of the anticancer potential of Yemeni plants used in folk medicine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="28676443" href="https://independent.academia.edu/RamziMothanaacademiaedu">Ramzi Mothana</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Die Pharmazie-An …, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Study of the anticancer potential of Yemeni plants used in folk medicine","attachmentId":77812909,"attachmentType":"pdf","work_url":"https://www.academia.edu/66736242/Study_of_the_anticancer_potential_of_Yemeni_plants_used_in_folk_medicine","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/66736242/Study_of_the_anticancer_potential_of_Yemeni_plants_used_in_folk_medicine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="78573751" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/78573751/Antiproliferative_activity_of_plant_extracts_used_against_cancer_in_traditional_medicine">Antiproliferative activity of plant extracts used against cancer in traditional medicine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="3795155" href="https://asu-jo.academia.edu/wamidhtalib">wamidh talib</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Scientia pharmaceutica, 2010</p><p class="ds-related-work--abstract ds2-5-body-sm">Forty four extracts from sixteen plants used traditionally as anticancer agents were evaluated in vitro for their antiproliferative activity against Hep-2, MCF-7, and Vero cell lines. Plants were fractionated using ethanol, methanol, chloroform, n-hexane, distilled water, and butanol. The antiproliferative activity was measured by MTT assay. TLC was used to identify active fractions. The apoptotic activity of active fractions was determined using TUNEL colorimetric assay. 20 of these extracts demonstrated significant antiproliferative activity against one or more of the cell lines. These extracts were prepared from Ononis hirta, Inula viscosa, Salvia pinardi, Verbascum sinaiticum and Ononis sicula. Methanol fractions of Ononis hirta (aerial parts) and Inula viscosa (flowers) were the most active fractions against MCF-7 cells with IC(50) of 27.96 and 15.78 Îg/ml respectively and they were less toxic against other cell lines. Other extracts showed lower activity against cancer cell li...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Antiproliferative activity of plant extracts used against cancer in traditional medicine","attachmentId":85785926,"attachmentType":"pdf","work_url":"https://www.academia.edu/78573751/Antiproliferative_activity_of_plant_extracts_used_against_cancer_in_traditional_medicine","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/78573751/Antiproliferative_activity_of_plant_extracts_used_against_cancer_in_traditional_medicine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":101223232,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":101223232,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_101223232" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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