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Merr. &amp; L.M.Perry, leaves of Volkameria inermis L. (syn. Clerodendrum inerme L.) whole plant of Sphaeranthus amaranthoides Burm.f. and combination of these three drugs were studied" /> <meta name="twitter:image" content="http://a.academia-assets.com/images/twitter-card.jpeg" /> <meta property="fb:app_id" content="2369844204" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.academia.edu/50705599/CYTOTOXIC_STUDIES_ON_SELECTED_MEDICINAL_PLANTS" /> <meta property="og:title" content="CYTOTOXIC STUDIES ON SELECTED MEDICINAL PLANTS" /> <meta property="og:image" content="http://a.academia-assets.com/images/open-graph-icons/fb-paper.gif" /> <meta property="og:description" content="Methanolic extract of flower bud of Syzygium aromaticum (L.) Merr. &amp; L.M.Perry, leaves of Volkameria inermis L. (syn. Clerodendrum inerme L.) whole plant of Sphaeranthus amaranthoides Burm.f. and combination of these three drugs were studied" /> <meta property="article:author" content="https://independent.academia.edu/ELANKANIPOOVAN" /> <meta name="description" content="Methanolic extract of flower bud of Syzygium aromaticum (L.) Merr. &amp; L.M.Perry, leaves of Volkameria inermis L. (syn. Clerodendrum inerme L.) whole plant of Sphaeranthus amaranthoides Burm.f. and combination of these three drugs were studied" /> <title>(PDF) CYTOTOXIC STUDIES ON SELECTED MEDICINAL PLANTS | ELANKANI POOVAN - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/50705599/CYTOTOXIC_STUDIES_ON_SELECTED_MEDICINAL_PLANTS" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = 'c7c923e13c2d00b99cbe85c9159af2026a636b1c'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732712907000); window.Aedu.timeDifference = new Date().getTime() - 1732712907000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Methanolic extract of flower bud of Syzygium aromaticum (L.) Merr. \u0026amp;amp; L.M.Perry, leaves of Volkameria inermis L. (syn. Clerodendrum inerme L.) whole plant of Sphaeranthus amaranthoides Burm.f. and combination of these three drugs were studied cytotoxic activity against a human hepato cellular carcinoma cell line, Hep G2 in different concentrations (10, 20, 40 \u0026amp;amp; 80μg/ml) along with standard drug Adriamycin (Doxorubicin)(ADA)(Positive control compound). The results showed that all the extracts were non-cytotoxic at the dose levels studied and all of them showed GI50 only at concentration \u0026amp;gt; 80 μg/ml.","author":[{"@context":"https://schema.org","@type":"Person","name":"ELANKANI POOVAN"}],"contributor":[],"dateCreated":"2021-08-04","dateModified":"2021-08-04","datePublished":"2016-01-01","headline":"CYTOTOXIC STUDIES ON SELECTED MEDICINAL PLANTS","inLanguage":"en","keywords":["Pharmacology","Toxicology","Syzygium aromaticum"],"locationCreated":null,"publication":"European Journal of Biomedical and pharmaceutical sciences","publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/50705599/CYTOTOXIC_STUDIES_ON_SELECTED_MEDICINAL_PLANTS","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" 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Merr. \u0026 L.M.Perry, leaves of Volkameria inermis L. (syn. Clerodendrum inerme L.) whole plant of Sphaeranthus amaranthoides Burm.f. and combination of these three drugs were studied cytotoxic activity against a human hepato cellular carcinoma cell line, Hep G2 in different concentrations (10, 20, 40 \u0026 80μg/ml) along with standard drug Adriamycin (Doxorubicin)(ADA)(Positive control compound). The results showed that all the extracts were non-cytotoxic at the dose levels studied and all of them showed GI50 only at concentration \u003e 80 μg/ml.","publication_date":"2016,,","publication_name":"European Journal of Biomedical and pharmaceutical sciences"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"CYTOTOXIC STUDIES ON SELECTED MEDICINAL PLANTS","broadcastable":true,"draft":false,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [43698188]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":68585701,"attachmentType":"pdf"}"><img alt="First page of “CYTOTOXIC STUDIES ON SELECTED MEDICINAL PLANTS”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/68585701/mini_magick20210804-18281-15zwzxo.png?1628063565" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">CYTOTOXIC STUDIES ON SELECTED MEDICINAL PLANTS</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="43698188" href="https://independent.academia.edu/ELANKANIPOOVAN"><img alt="Profile image of ELANKANI POOVAN" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />ELANKANI POOVAN</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2016, European Journal of Biomedical and pharmaceutical sciences</p></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Methanolic extract of flower bud of Syzygium aromaticum (L.) Merr. & L.M.Perry, leaves of Volkameria inermis L. (syn. Clerodendrum inerme L.) whole plant of Sphaeranthus amaranthoides Burm.f. and combination of these three drugs were studied cytotoxic activity against a human hepato cellular carcinoma cell line, Hep G2 in different concentrations (10, 20, 40 & 80μg/ml) along with standard drug Adriamycin (Doxorubicin)(ADA)(Positive control compound). The results showed that all the extracts were non-cytotoxic at the dose levels studied and all of them showed GI50 only at concentration > 80 μg/ml.</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":68585701,"attachmentType":"pdf","workUrl":"https://www.academia.edu/50705599/CYTOTOXIC_STUDIES_ON_SELECTED_MEDICINAL_PLANTS"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":68585701,"attachmentType":"pdf","workUrl":"https://www.academia.edu/50705599/CYTOTOXIC_STUDIES_ON_SELECTED_MEDICINAL_PLANTS"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="68585701" data-landing_url="https://www.academia.edu/50705599/CYTOTOXIC_STUDIES_ON_SELECTED_MEDICINAL_PLANTS" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="3053125" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/3053125/EVALUATION_OF_CYTOTOXICITY_OF_SOME_SELECTED_MEDICINAL_PLANTS_EVALUATION_OF_CYTOTOXICITY_OF_SOME_SELECTED_MEDICINAL_PLANTS">EVALUATION OF CYTOTOXICITY OF SOME SELECTED MEDICINAL PLANTS EVALUATION OF CYTOTOXICITY OF SOME SELECTED MEDICINAL PLANTS</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="3510100" href="https://gadjamadauniversity.academia.edu/PriyoAtmaja">Priyo Atmaja</a></div><p class="ds-related-work--metadata ds2-5-body-xs">arpb.info</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"EVALUATION OF CYTOTOXICITY OF SOME SELECTED MEDICINAL PLANTS EVALUATION OF CYTOTOXICITY OF SOME SELECTED MEDICINAL PLANTS","attachmentId":30983003,"attachmentType":"pdf","work_url":"https://www.academia.edu/3053125/EVALUATION_OF_CYTOTOXICITY_OF_SOME_SELECTED_MEDICINAL_PLANTS_EVALUATION_OF_CYTOTOXICITY_OF_SOME_SELECTED_MEDICINAL_PLANTS","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/3053125/EVALUATION_OF_CYTOTOXICITY_OF_SOME_SELECTED_MEDICINAL_PLANTS_EVALUATION_OF_CYTOTOXICITY_OF_SOME_SELECTED_MEDICINAL_PLANTS"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="106281123" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/106281123/ETHNOPHARMACOLOGICAL_EVALUATION_OF_MEDICINAL_PLANTS_FOR_CYTOTOXICITY_AGAINST_VARIOUS_CANCER_CELL_LINES_Original_Article">ETHNOPHARMACOLOGICAL EVALUATION OF MEDICINAL PLANTS FOR CYTOTOXICITY AGAINST VARIOUS CANCER CELL LINES Original Article</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="265496504" href="https://independent.academia.edu/InternationalJournalofPharmacyandPharmaceuticalSciencesIJPPS">International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Pharmacy and Pharmaceutical Sciences, 2017</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective: To evaluate the cytotoxic potential of leaves and seeds of Hibiscus sabdariffa L., fruit juice of Phyllanthus emblica, rhizomes of Dryopteris cochleata and flowers of Caesalpinia decapetala (Roth) Alston along with the chemical profiling of the most toxic extract through Gas-mass spectroscopy-MS technique. Methods: The hydroalcoholic extract of the selected crude drugs was prepared by maceration method and the extracts were undergone through phytochemical analysis. The cytotoxic activity of the hydroalcoholic extract was performed against four cancer cell lines i.e. liver (HepG2), breast (MCF7), prostate (PC-3) and leukemia (HL60) using sulphorhodamine B assay. The hydroalcoholic extract of Caesalpinia decapetala flowers was profiled through using gas mass spectroscopy. Results: The results confirmed that Phyllanthus emblica inhibited HL60 cancer cells at the dose of 35.6 µg/ml and show dose-dependent growth inhibition. The flowers of Caesalpinia decapetala inhibited nearly fifty percent of HL60 cancer cells at very low dose i. e 10 µg/ml. The analysis of Caesalpinia decapetala flowers shows the presence of diterpenoid furanolactones, bufadienolides, polycyclic enones, and androsterone. Conclusion: The fruit juice of Phyllanthus emblica and flowers of Caesalpinia decapetala showed good inhibitory activity against HL60 cancer cell line. The use of Phyllanthus emblica in herbal medicine is justified. The data obtained impelled to further assess the in vivo efficacy of Caesalpinia decapetala flowers for anticancer activity.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"ETHNOPHARMACOLOGICAL EVALUATION OF MEDICINAL PLANTS FOR CYTOTOXICITY AGAINST VARIOUS CANCER CELL LINES Original Article","attachmentId":105520077,"attachmentType":"pdf","work_url":"https://www.academia.edu/106281123/ETHNOPHARMACOLOGICAL_EVALUATION_OF_MEDICINAL_PLANTS_FOR_CYTOTOXICITY_AGAINST_VARIOUS_CANCER_CELL_LINES_Original_Article","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/106281123/ETHNOPHARMACOLOGICAL_EVALUATION_OF_MEDICINAL_PLANTS_FOR_CYTOTOXICITY_AGAINST_VARIOUS_CANCER_CELL_LINES_Original_Article"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="52979313" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/52979313/In_Vitro_Screening_for_Cytotoxic_Activity_of_Herbal_Extracts">In Vitro Screening for Cytotoxic Activity of Herbal Extracts</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38392260" href="https://independent.academia.edu/Ram%C3%B3nCacabelos">Ramón Cacabelos</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Evidence-Based Complementary and Alternative Medicine</p><p class="ds-related-work--abstract ds2-5-body-sm">Experimental studies have shown that a variety of chemopreventive plant components affect tumor initiation, promotion, and progression and the main difference, between botanical medicines and synthetic drugs, resides in the presence of complex metabolite mixtures shown by botanical medicine which in turn exert their action on different levels and via different mechanisms. In the present study, we performed an in vitro screening of ethanol extracts from commercial plants in order to investigate potential antitumor activity against human tumor cell lines. Experimental results obtained through a variety of methods and techniques indicated that extracts ofI. verum,G. glabra,R. Frangula, andL. usitatissimumpresent significant reduction inin vitrotumor cell proliferation, suggesting these extracts as possible chemotherapeutical adjuvants for different cancer treatments.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"In Vitro Screening for Cytotoxic Activity of Herbal Extracts","attachmentId":69980127,"attachmentType":"pdf","work_url":"https://www.academia.edu/52979313/In_Vitro_Screening_for_Cytotoxic_Activity_of_Herbal_Extracts","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/52979313/In_Vitro_Screening_for_Cytotoxic_Activity_of_Herbal_Extracts"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="108503995" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/108503995/Cytotoxic_Properties_of_Some_Medicinal_Plant_Extracts_from_Mazandaran_Iran">Cytotoxic Properties of Some Medicinal Plant Extracts from Mazandaran, Iran</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="274313022" href="https://independent.academia.edu/FarkhondehNemati">Farkhondeh Nemati</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Iranian Red Crescent Medical Journal, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cytotoxic Properties of Some Medicinal Plant Extracts from Mazandaran, Iran","attachmentId":106868325,"attachmentType":"pdf","work_url":"https://www.academia.edu/108503995/Cytotoxic_Properties_of_Some_Medicinal_Plant_Extracts_from_Mazandaran_Iran","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/108503995/Cytotoxic_Properties_of_Some_Medicinal_Plant_Extracts_from_Mazandaran_Iran"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="9297736" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/9297736/Cytotoxicity_potentials_of_eleven_Bangladeshi_medicinal_plants">Cytotoxicity potentials of eleven Bangladeshi medicinal plants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7411416" href="https://manarat.academia.edu/AminaKhatun">Amina Khatun</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="1411297" href="https://scu-au.academia.edu/MahmudurRahman">Mahmudur Rahman</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Various forms of cancer are rising all over the world, requiring newer therapy. The quest of anti-cancer drugs both from natural and synthetic sources is the demand of time. In this study, fourteen extracts of different parts of eleven Bangladeshi medicinal plants which have been traditionally used for the treatment of different types of carcinoma, tumor, leprosy and diseases associated with cancer were evaluated for their cytotoxicity for the first time. Extraction was conceded using methanol. Phytochemical groups like reducing sugars, tannins, saponins, steroids, gums, flavonoids and alkaloids were tested using standard chromogenic reagents. Plants were evaluated for cytotoxicity by brine shrimp lethality bioassay using Artemia salina comparing with standard anti-cancer drug vincristine sulphate. All the extracts showed potent to moderate cytotoxicity ranging from LC50 2 to 115 µg/ml. Highest toxicity was shown by Hygrophila spinosa seeds (LC50 = 2.93µg/ml) and lowest by Litsea glutinosa leaves (LC50 = 114.71 µg/ml) in comparison with standard vincristine sulphate (LC50 = 2.04 µg/ml). Among the plants, the plants traditionally used in different cancer and microbial treatment showed highest cytotoxicity. The results support their ethnomedicinal uses and require advanced investigation to elucidate responsible compounds as well as their mode of action.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cytotoxicity potentials of eleven Bangladeshi medicinal plants","attachmentId":35558507,"attachmentType":"pdf","work_url":"https://www.academia.edu/9297736/Cytotoxicity_potentials_of_eleven_Bangladeshi_medicinal_plants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/9297736/Cytotoxicity_potentials_of_eleven_Bangladeshi_medicinal_plants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="98686168" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/98686168/Cytotoxic_Activities_of_Certain_Medicinal_Plants_on_Different_Cancer_Cell_Lines">Cytotoxic Activities of Certain Medicinal Plants on Different Cancer Cell Lines</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="262028830" href="https://independent.academia.edu/HaticeGunes6">Hatice Gunes</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Turkish Journal of Pharmaceutical Sciences</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cytotoxic Activities of Certain Medicinal Plants on Different Cancer Cell Lines","attachmentId":99969924,"attachmentType":"pdf","work_url":"https://www.academia.edu/98686168/Cytotoxic_Activities_of_Certain_Medicinal_Plants_on_Different_Cancer_Cell_Lines","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/98686168/Cytotoxic_Activities_of_Certain_Medicinal_Plants_on_Different_Cancer_Cell_Lines"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="13396430" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/13396430/Cytotoxic_activity_screening_of_Bangladeshi_medicinal_plant_extracts">Cytotoxic activity screening of Bangladeshi medicinal plant extracts</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32620700" href="https://independent.academia.edu/EvelinTiralongo">Evelin Tiralongo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Natural Medicines, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cytotoxic activity screening of Bangladeshi medicinal plant extracts","attachmentId":45388858,"attachmentType":"pdf","work_url":"https://www.academia.edu/13396430/Cytotoxic_activity_screening_of_Bangladeshi_medicinal_plant_extracts","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/13396430/Cytotoxic_activity_screening_of_Bangladeshi_medicinal_plant_extracts"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="85691908" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/85691908/Cytotoxicity_Activity_of_Some_Indian_Medicinal_Plants">Cytotoxicity Activity of Some Indian Medicinal Plants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37032749" href="https://andhrauniversity.academia.edu/MallikarjunaRaoTalluri">Mallikarjuna Rao Talluri</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Current Pharmaceutical Research, 2016</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective: The current study is carried out to evaluate cytotoxicity activity of the methanolic extracts of some medicinal (Buchanania axillaris Desr, Tamilnadia ulignosa Retz, Phaseolus semierectus L and Stylosanthes fruticosa Retz).Methods: Cytotoxicity activity was evaluated on human cancer cell lines such as lung cancer (A549) and skin cancer (A431) using MTT assay method.Results: The selected plant extracts showed the dose-dependent cytotoxicity activity on the tested cell lines. The cytotoxicity variations on different cell lines were also observed for tested plants extracts. The cytotoxicity of the extracts was increased as the concentration of them was increased. Among all tested plants extracts Phaseolus semierectus showed the better cytotoxicity activity on tested cell lines. Conclusion: The results of the present study supported the folkloric usage of the studied plants and confirmed that the plant&#39;s extracts have the bioactive constituents with cytotoxic properties a...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cytotoxicity Activity of Some Indian Medicinal Plants","attachmentId":90313191,"attachmentType":"pdf","work_url":"https://www.academia.edu/85691908/Cytotoxicity_Activity_of_Some_Indian_Medicinal_Plants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/85691908/Cytotoxicity_Activity_of_Some_Indian_Medicinal_Plants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="5276305" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/5276305/Cytotoxic_Activity_of_Four_Mexican_Medicinal_Plants">Cytotoxic Activity of Four Mexican Medicinal Plants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="6110059" href="https://uam-mx.academia.edu/AdolfoEspejoSerna">Adolfo Espejo-Serna</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cytotoxic Activity of Four Mexican Medicinal Plants","attachmentId":49368775,"attachmentType":"pdf","work_url":"https://www.academia.edu/5276305/Cytotoxic_Activity_of_Four_Mexican_Medicinal_Plants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/5276305/Cytotoxic_Activity_of_Four_Mexican_Medicinal_Plants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="23914252" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23914252/Cytotoxic_Activity_of_Selected_Iranian_Traditional_Medicinal_Plants_on_Colon_Colorectal_and_Breast_Cancer_Cell_Lines">Cytotoxic Activity of Selected Iranian Traditional Medicinal Plants on Colon, Colorectal and Breast Cancer Cell Lines</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32669728" href="https://independent.academia.edu/NSadati">N. Sadati</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="34717060" href="https://independent.academia.edu/MahnazKhanavi">Mahnaz Khanavi</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cytotoxic Activity of Selected Iranian Traditional Medicinal Plants on Colon, Colorectal and Breast Cancer Cell Lines","attachmentId":44301703,"attachmentType":"pdf","work_url":"https://www.academia.edu/23914252/Cytotoxic_Activity_of_Selected_Iranian_Traditional_Medicinal_Plants_on_Colon_Colorectal_and_Breast_Cancer_Cell_Lines","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23914252/Cytotoxic_Activity_of_Selected_Iranian_Traditional_Medicinal_Plants_on_Colon_Colorectal_and_Breast_Cancer_Cell_Lines"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":68585701,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":68585701,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_68585701" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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