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<!DOCTYPE html> <html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#"> <head> <meta charset="utf-8" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-9M4L5ZJ47J"></script> <script>window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag("js", new Date());gtag("set", "developer_id.dMDhkMT", true);gtag("config", "G-9M4L5ZJ47J", {"groups":"default","page_placeholder":"PLACEHOLDER_page_location","allow_ad_personalization_signals":false});</script> <meta name="description" content="The Vision of Experimental Therapeutics is to define better intervention strategies for individuals with aggressive cancers through: (i) a better understanding of disease classification and patient selection criteria, (ii) development and use of more predictive models (e.g." /> <link rel="canonical" href="https://www.bccrc.ca/dept/et/programs" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <style>.logo a {background-image: url(/dept/et/sites/experimentaltherapeutics/files/BCClogo_Research_ExperimentalTherapeutics_RGB.png);background-size: contain;}body .region__network .logo a {background-size: contain}</style> <link rel="icon" href="/dept/et/themes/custom/bccrc/favicon.ico" type="image/vnd.microsoft.icon" /> <title>Programs | Experimental Therapeutics</title> <link rel="stylesheet" href="//use.typekit.net/rew6qot.css"> <link rel="stylesheet" media="all" href="/dept/et/sites/experimentaltherapeutics/files/css/css_ey_ugW0R6-Dv9mM3z5uVLqTrM-kdw_Fg0VmFvE0AoXg.css?delta=0&language=en&theme=bccrc&include=eJxFyDEOwCAIAMAPWXkTKEETqgRk8Pcde-PFjcMvEAYXas0biG5CfeJcnUuKoaM42gjonoZa_6m5LElnDO4fGXccpA" /> <link rel="stylesheet" media="all" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/4.7.0/css/font-awesome.min.css" /> <link rel="stylesheet" media="all" href="/dept/et/sites/experimentaltherapeutics/files/css/css_f9vSMEfaUUj1Vi5S5OMU9J-eyVOUVzkdzlMftZl9VdI.css?delta=2&language=en&theme=bccrc&include=eJxFyDEOwCAIAMAPWXkTKEETqgRk8Pcde-PFjcMvEAYXas0biG5CfeJcnUuKoaM42gjonoZa_6m5LElnDO4fGXccpA" /> </head> <body class="colour--mahogany not-front path--node page--page"> <a href="#main-content" class="visually-hidden focusable skip-link"> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div class="main-container"> <header class="page--page page"> <div class="region__header--inner region--inner"> <section id="block-bccrc-breadcrumbs" class="block block--system-breadcrumb-block block-bccrc-breadcrumbs"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/dept/et/">Experimental Therapeutics</a> </li> <li> Programs </li> </ol> </nav> </section> <section id="block-bccrc-page-title" class="block block--page-title-block block-bccrc-page-title"> <h1><span>Programs</span> </h1> </section> </div> </header> <section class="region region__highlight"> <div class="region__highlight--inner region--inner"> <div data-drupal-messages-fallback class="hidden"></div> </div> </section> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <section class="region region__content"> <div class="region__content--inner region--inner"> <section id="block-bccrc-content" class="block block--system-main-block block-bccrc-content"> <article class="node node--page full"> <div class="field field--body"><p>The Vision of Experimental Therapeutics is to define better intervention strategies for individuals with aggressive cancers through: (i) a better understanding of disease classification and patient selection criteria, (ii) development and use of more predictive models (e.g. patient-derived cancer xenograft models) for targeted indications, (iii) a better understanding of tumor-stromal interactions and mechanistic actions of targeted therapies; (iv) integration of relevant imaging tools to rapidly assess therapeutic potential of treatments, (v) application of genetic information to better understand the immediate impacts of treatment and how to design better treatments, (vi) application of high-throughput, next generation genomics approaches to novel discovery of new therapeutics and (vii) maintenance and expansion of the needed infrastructure to develop therapeutics in an academic setting.</p></div> </article> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--79"> <h2 class="section__title" data-expand="field--field_text">Investigational Drug Program</h2> <div class="field field--field_expanding_summary">The Investigational Drug Program (IDP) specializes in providing extensive research services for your preclinical, manufacturing and research support needs.</div> <button class="icon" data-expand></button> <div class="field field--field_text"> <p><img alt="pharmaceutical value chain" data-entity-type data-entity-uuid src="https://www.bccrc.ca/dept/et/sites/experimentaltherapeutics/files/Pharmaceutical%20value%20chain_1.png" class="align-center"></p> <p>IDP is positioned to conduct the stages of the pharmaceutical value chain including: discovery, pharmaceutical formulation, manufacturing and preclinical / safety pharmacology testing activities required to initiate first in-human clinical trials and to ensure Good Manufacturing Practice (cGMP) and Good Laboratory Practice (cGLP) regulations are met.</p></div> <div class="field field--field_link"><a href="/dept/et/services/investigational-drug-program">Learn More</a></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--80"> <h2 class="section__title" data-expand="field--field_text">Pancreas Centre BC</h2> <div class="field field--field_expanding_summary">Pancreas Centre BC was established in 2012 as a multicentre partnership between BC Cancer, Vancouver Coastal Health and University of British Columbia. Its mission is to combat pancreatic cancer and our team is committed to foster and lead research into early disease detection and the development of personalized treatments in pancreatic cancer.</div> <button class="icon" data-expand></button> <div class="field field--field_text"> <p>Despite decades of intense research, the five-year overall survival rate in pancreatic cancer is less than 10% due to late detection, high recurrence rates, chemoresistance and limited knowledge of clinically relevant biomarkers. <em>Pancreas Centre BC</em> was established in 2012 as a multicentre partnership between BC Cancer, Vancouver Coastal Health and University of British Columbia. Its mission is to combat pancreatic cancer and our team is committed to foster and lead research into early disease detection and the development of personalized treatments in pancreatic cancer. The centre strives to become a centre of excellence for translational and clinical pancreatic cancer research and patient care, and focuses on four major goals:</p> <ol> <li><strong>Lead</strong> the development and implementation of individualized care in pancreatic cancer;</li> <li><strong>Support</strong> translational and clinical research, as well as local, national and international collaborations to accelerate clinically relevant discovery;</li> <li><strong>Provide</strong> mentorship to future researchers and clinical leaders;</li> <li><strong>Deliver</strong> short term and significant impact on outcomes for patients at BC Cancer.</li> </ol> <p>One of the strengths of <em>Pancreas Centre BC</em> is its multidisciplinary team with expertise in clinical care, clinical trials and translational research. Research focuses on integration of multi-omics, clinical parameter and outcome data. Our team is comprised of clinicians, clinical support, scientific, technical, bioinformatics and biostatistics personnel with unique and diverse expertise. We support a collaborative research culture by engaging with local and national research and clinical care centres. To this end, <em>Pancreas Centre BC </em>has developed unique core resources accessible to clinical and scientific research community including a clinical outcomes unit, a tumour biobank, a tissue microarray and a patient-derived pre-clinical model facility.</p> <p><img alt="Pancreas Team" data-entity-type data-entity-uuid src="https://www.bccrc.ca/dept/et/sites/experimentaltherapeutics/files/styles/DSC08197.jpg" class="align-center"></p> <p><em>Pancreas Centre BC </em>is part of PancOne, a national collaborative network funded by Pancreatic Cancer Canada (PCC). We also lead a national initiative funded by the Terry Fox Research Institute, Pancreatic Cancer Canada and BC Cancer Foundation called the Enhanced Pancreatic Cancer Profiling for Individualized Care (EPPIC) project, which aims to sequence and molecularly characterize up to 400 metastatic pancreatic cancers in order to accelerate the development and clinical implementation of personalized medicine. As a clinical research centre, <em>Pancreas Centre BC</em> is in a unique position to develop a path towards the validation and implementation of novel clinical approaches to treat pancreatic cancer.</p> <p>More information at <a href="http://www.pancreascentrebc.ca">www.pancreascentrebc.ca</a></p></div> </section> </section> <section class="programs-form block block--programs-block block-programsblock" data-drupal-selector="programs-form" id="block-programsblock"> <form action="/dept/et/programs" method="post" id="programs-form" accept-charset="UTF-8"> <div class="results-region"><nav class="pager pager--mini"><ul><li class="prev visible"><a rel="prev" href="?page=1"></a></li><li class="next hidden"><a rel="next" href="?page=3"></a></li></ul></nav></div><input data-drupal-selector="form-kuihra1c88mnotbcz-vhbc60qsyywudxumhztrm0afk" type="hidden" name="form_build_id" value="form-kUiHra1C88mNOTBCZ-vHBc60qsYywUdxumhZTrm0aFk" /> <input data-drupal-selector="edit-programs-form" type="hidden" name="form_id" value="programs_form" /> </form> </section> </div> </section> </div> <a class="top" href="#main-content">Back to top</a> </main> <section class="region region__cta"> <div class="region__cta--inner region--inner"> <section id="block-sitecalltoaction" class="block block--block-contenta8a59224-4648-42d5-b71c-294b3c630d8a block-sitecalltoaction"> <div class="field field--body"><p>BC Cancer Foundation is the fundraising partner of BC Cancer, which includes BC Cancer Research. Together with our donors, we are changing cancer outcomes for British Columbians by funding innovative research and personalized treatment and care.</p> <p><a class="button" href="https://bccancerfoundation.com/donations/general-donation-form/?s_src=BCCRCFooter" target="_blank">Donate Today</a></p></div> </section> </div> </section> <footer class="page" role="contentinfo"> <section class="region region__footer"> <div class="region__footer--inner region--inner"> <section id="block-bccrc-branding" class="block block--system-branding-block block-bccrc-branding"> <a href="/dept/et/" title="Home" rel="home"> <img src="/dept/et/sites/experimentaltherapeutics/files/BCClogo_Research_ExperimentalTherapeutics_RGB.png" alt="Home" /> </a> </section> <section id="block-contactus" class="block block--block-content2314a90f-9af6-4a1e-8cf5-6a294688e075 block--contact-us block-contactus"> <h2 class="section__title">Contact Us</h2> <div class="field field--body"><p>BC Cancer Research Institute<br> 675 West 10th Avenue<br> Vancouver, BC V5Z 1L3</p> <p>604 675 8000</p> <p>Toll Free: 1 888 675 8001</p></div> </section> <section id="block-followus" class="block block--block-content06fb6d8a-948b-4134-bf4f-c16a4f797215 block--follow-us block-followus"> <h2 class="section__title">Follow Us</h2> <div class="field field--body"><p><a class="fa fa-linkedin" href="https://www.linkedin.com/company/bc-cancer/"> </a><a class="fa fa-twitter" href="https://twitter.com/BCCancer"> </a><a class="fa fa-instagram" href="https://www.instagram.com/bccancer/"> </a></p></div> </section> <section id="block-phsa" class="block block--block-content288c07b1-9e42-46f4-a804-fdd18540fbad block-phsa"> <div class="field field--body"><p><a href="http://www.phsa" target="_blank"><img alt="PHSA" src="https://www.bccrc.ca/dept/et/sites/experimentaltherapeutics/files/PHSA-logo.svg"></a></p></div> </section> </div> </section> </footer> <section class="region region__copyright"> <div class="region__copyright--inner region--inner"> <nav role="navigation" aria-labelledby="block-bccrc-footer-menu" id="block-bccrc-footer"> <h2 class="visually-hidden" id="block-bccrc-footer-menu">Footer menu</h2> <ul class="menu"> <li class="menu-item"> <a href="http://www.phsa.ca/privacy">Privacy Policy</a> </li> <li>Copyright © BC Cancer. 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