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<!DOCTYPE html> <html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#"> <head> <meta charset="utf-8" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-D7EXFRJXP0"></script> <script>window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag("js", new Date());gtag("set", "developer_id.dMDhkMT", true);gtag("config", "G-D7EXFRJXP0", {"groups":"default","page_placeholder":"PLACEHOLDER_page_location","allow_ad_personalization_signals":false});</script> <meta name="description" content="Improving patient outcomes by gaining a deeper understanding of lymphoma biology and progression, for use in clinical application" /> <link rel="shortlink" href="https://www.bccrc.ca/dept/lcr/" /> <link rel="canonical" href="https://www.bccrc.ca/dept/lcr/" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <style>.logo a {background-image: url(/dept/lcr/sites/lymphoidcancer/files/BCClogo_Research_LymphoidCancer_RGB.png);background-size: contain;}body .region__network .logo a {background-size: contain}</style> <style>#what-we-do .background {background-image: url(https://www.bccrc.ca/dept/lcr/sites/lymphoidcancer/files/styles/400w/public/2019-10/LCR_Callout01.jpg?itok=yKxg7e87)}</style> <style>.carousel__slide_38 {background-image: url(https://www.bccrc.ca/dept/lcr/sites/lymphoidcancer/files/styles/header/public/2019-10/LCR_Banner.jpeg?itok=tnFY0FRC)} @media (min-width: 600px) { .carousel__slide_38 {background-image: url(https://www.bccrc.ca/dept/lcr/sites/lymphoidcancer/files/styles/carousel/public/2019-10/LCR_Banner.jpeg?itok=oiXe3PJ9)}}</style> <link rel="icon" href="/dept/lcr/themes/custom/bccrc/favicon.ico" type="image/vnd.microsoft.icon" /> <title>Lymphoid Cancer Research</title> <link rel="stylesheet" href="//use.typekit.net/rew6qot.css"> <link rel="stylesheet" media="all" href="/dept/lcr/sites/lymphoidcancer/files/css/css_nYWlFnEygeNSjbTAchYRcwUV5SV9RXtwiJlGbdI-_Tc.css?delta=0&language=en&theme=bccrc&include=eJxFyEEKwzAMBdELqfaZvmThuCixkaK2uX0hULoZmMciLlXgM0ON-N5uk2GPOC8bRyeZrrV5LljBEx9acHTH2uLHfyl5rGQbsWmjuOLUvTJC6TX0HfVu2WdL0y-rOzAj" /> <link rel="stylesheet" media="all" href="/dept/lcr/sites/lymphoidcancer/files/css/css_c_M5VvJkbKVs1ZmYN8FBs07xuEnQ_GtFDXXNhkMTXvg.css?delta=1&language=en&theme=bccrc&include=eJxFyEEKwzAMBdELqfaZvmThuCixkaK2uX0hULoZmMciLlXgM0ON-N5uk2GPOC8bRyeZrrV5LljBEx9acHTH2uLHfyl5rGQbsWmjuOLUvTJC6TX0HfVu2WdL0y-rOzAj" /> <link rel="stylesheet" media="all" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/4.7.0/css/font-awesome.min.css" /> <link rel="stylesheet" media="all" href="/dept/lcr/sites/lymphoidcancer/files/css/css_b1Imd5Zfo6d9UtggtC_ak93-Ac2c67PnthKR5yWdzt8.css?delta=3&language=en&theme=bccrc&include=eJxFyEEKwzAMBdELqfaZvmThuCixkaK2uX0hULoZmMciLlXgM0ON-N5uk2GPOC8bRyeZrrV5LljBEx9acHTH2uLHfyl5rGQbsWmjuOLUvTJC6TX0HfVu2WdL0y-rOzAj" /> </head> <body class="colour--spruce has-carousel front page--front"> <a href="#main-content" class="visually-hidden focusable skip-link"> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div class="main-container"> <header class="page--front has-carousel page"> <div class="region__header--inner region--inner"> <nav role="navigation" aria-labelledby="block-utility-menu" id="block-utility"> <h2 class="visually-hidden" id="block-utility-menu">Utility</h2> <ul class="menu"> <li class="menu-item"> <a href="https://www.bccrc.ca/dept/cid" target="_blank"><span class="nomobile">For Patients - </span>Find a Clinical Trial</a> </li> </ul> </nav> <section class="views-element-container block block--views-blockcarousel-block-1 block-views-block-carousel-block-1" id="block-views-block-carousel-block-1"> <div><div class="js-view-dom-id-344bf01572b2021319e6e73ab63d185b91250ede77e42ab50de4f03ce2c4b773 view view--carousel"> <div class="views-row"><div class="views-field views-field-field-carousel"><div class="field-content"><div class="field field--carousel carousel" data-timeout="5000" data-slides=".layout__carousel_slide"> <section class="layout layout__carousel_slide layout__parent__node carousel__slide_38 tinted" id="paragraph--38"> <div class="inner"> <h2 class="section__title">Lymphoid Cancer Research</h2> </div> </section> </div> </div></div></div> </div> </div> </section> </div> </header> <section class="region region__highlight"> <div class="region__highlight--inner region--inner"> <div data-drupal-messages-fallback class="hidden"></div> </div> </section> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <section class="region region__content"> <div class="region__content--inner region--inner"> <section id="block-bccrc-content" class="block block--system-main-block block-bccrc-content"> <article class="node node--front full"> </article> <section class="layout layout__callout layout__parent__node has-background paragraph paragraph--type--callout paragraph--view-mode--default" id="what-we-do"> <div class="section__title"><h2 class="section__title">What We Do</h2></div> <div class="inner"> <div class="background"> </div> <div class="field field--summary"> <p>Our main research focus is to improve patient outcomes by gaining deeper understanding of lymphoma biology and disease progression which can be translated into clinical applications. Our ultimate goal is to improve patient outcomes through enhanced precision medicine, which can be designed using advanced genomic tools.</p> </div> </div> </section> <section class="layout layout__news layout__parent__node paragraph paragraph--type--news paragraph--view-mode--default" id="paragraph--50"> <h2 class="section__title">News & Events</h2><div class="inner"><div class="featured has-teasers"><article class="node--article teaser"> <a href="/dept/lcr/news/recipients-bc-cancer-foundation-2024-rising-stars-award-competition-announced" class="image"><figure class="remote-image"><img src="//www.bccrc.ca/sites/bccrc.ca/files/styles/large/public/2024-12/Rising%20Stars%202024.png?itok=UvRhGz5Z" alt=""></figure></a> <div class="node__inner"> <footer class="node"> <article> </article> <div> <span><time datetime="2024-12-03T09:24:51-08:00" title="Tuesday, December 3, 2024 - 9:24am">Dec 03, 2024</time> </span> </div> </footer> <h2 class="node__title"><a href="/dept/lcr/news/recipients-bc-cancer-foundation-2024-rising-stars-award-competition-announced" rel="bookmark"><span>Recipients of BC Cancer Foundation 2024 Rising Stars Award competition announced </span> </a></h2> <div class="field field--body"><p>Congratulations to the recipients of the BC Cancer Foundation (BCCF) 2024 Rising Stars Award competition!</p><p>This year’s awardees are: </p></div> <ul class="links inline"><li class="node-readmore"><a href="/dept/lcr/news/recipients-bc-cancer-foundation-2024-rising-stars-award-competition-announced" rel="tag" title="Recipients of BC Cancer Foundation 2024 Rising Stars Award competition announced " hreflang="en">More Info<span class="visually-hidden"> about Recipients of BC Cancer Foundation 2024 Rising Stars Award competition announced </span></a></li></ul> </div> </article> </div><div class="teasers"><article class="node--article teaser"> <a href="/dept/lcr/news/dr-ryan-morin-receives-canadian-cancer-society-bernard-and-francine-dorval-prize" class="image"><figure class="remote-image"><img src="//www.bccrc.ca/sites/bccrc.ca/files/styles/large/public/2024-09/Ryan%20Morin%20web.png?itok=uBmQItY5" alt=""></figure></a> <div class="node__inner"> <footer class="node"> <article> </article> <div> <span><time datetime="2024-09-06T10:00:42-07:00" title="Friday, September 6, 2024 - 10:00am">Sep 06, 2024</time> </span> </div> </footer> <h2 class="node__title"><a href="/dept/lcr/news/dr-ryan-morin-receives-canadian-cancer-society-bernard-and-francine-dorval-prize" rel="bookmark"><span>Dr. Ryan Morin receives Canadian Cancer Society Bernard and Francine Dorval Prize</span> </a></h2> <div class="field field--body"><p>Dr. Ryan Morin (Centre for Lymphoid Cancer) is the co-recipient of the <a>Canadian Cancer Society (CCS) Bernard and Francine Dorval Prize. </a></p><p>Dr. Morin is a national and international leader in his field of studying how changes to our genes lead to cancer. He has conducted cutting-edge research that has directly helped doctors understand, diagnose and better treat lymphomas. </p></div> <ul class="links inline"><li class="node-readmore"><a href="/dept/lcr/news/dr-ryan-morin-receives-canadian-cancer-society-bernard-and-francine-dorval-prize" rel="tag" title="Dr. Ryan Morin receives Canadian Cancer Society Bernard and Francine Dorval Prize" hreflang="en">More Info<span class="visually-hidden"> about Dr. Ryan Morin receives Canadian Cancer Society Bernard and Francine Dorval Prize</span></a></li></ul> </div> </article> <article class="node--article teaser"> <a href="/dept/lcr/news/new-class-biomarker-could-better-predict-treatment-outcomes-hodgkin-lymphoma" class="image"><figure class="remote-image"><img src="//www.bccrc.ca/sites/bccrc.ca/files/styles/large/public/2024-01/Lymphoma%20image%20cropped_0.png?itok=rtRXSaZ1" alt=""></figure></a> <div class="node__inner"> <footer class="node"> <article> </article> <div> <span><time datetime="2024-01-29T11:06:56-08:00" title="Monday, January 29, 2024 - 11:06am">Jan 29, 2024</time> </span> </div> </footer> <h2 class="node__title"><a href="/dept/lcr/news/new-class-biomarker-could-better-predict-treatment-outcomes-hodgkin-lymphoma" rel="bookmark"><span>New class of biomarker could better predict treatment outcomes for Hodgkin lymphoma</span> </a></h2> <div class="field field--body"><p>Researchers with BC Cancer have discovered a way to better predict treatment outcomes in patients with relapsed and refractory, or treatment-resistant, classic <a href="http://www.bccancer.bc.ca/health-info/types-of-cancer/blood-lymphoid/hodgkin-lymphoma">Hodgkin lymphoma</a>.</p></div> <ul class="links inline"><li class="node-readmore"><a href="/dept/lcr/news/new-class-biomarker-could-better-predict-treatment-outcomes-hodgkin-lymphoma" rel="tag" title="New class of biomarker could better predict treatment outcomes for Hodgkin lymphoma" hreflang="en">More Info<span class="visually-hidden"> about New class of biomarker could better predict treatment outcomes for Hodgkin lymphoma</span></a></li></ul> </div> </article> <article class="node--article teaser"> <a href="/dept/lcr/news/study-reveals-cause-different-outcomes-patients-experience-early-and-late-relapse-diffuse" class="image"><figure class="remote-image"><img src="//www.bccrc.ca/sites/bccrc.ca/files/styles/large/public/2023-07/DavidScott_headshot.jpg?itok=xoxEMMza" alt=""></figure></a> <div class="node__inner"> <footer class="node"> <article> </article> <div> <span><time datetime="2023-07-13T11:01:42-07:00" title="Thursday, July 13, 2023 - 11:01am">Jul 13, 2023</time> </span> </div> </footer> <h2 class="node__title"><a href="/dept/lcr/news/study-reveals-cause-different-outcomes-patients-experience-early-and-late-relapse-diffuse" rel="bookmark"><span>Study reveals cause for different outcomes for patients that experience early and late relapse of diffuse large B-cell lymphoma</span> </a></h2> <div class="field field--body"><p>A recent study conducted by TFRI-funded researchers at BC Cancer sheds light on the cause behind the different outcomes of patients with diffuse large B cell lymphoma (DLBCL) who experienced a relapse in their disease. The study confirmed that patients whose cancer relapses shortly after treatment typically have poor responses to additional chemotherapy-based treatment. However, when the relapse occurs more than two years from the time of diagnosis, the outcomes to chemotherapy are significantly better.</p></div> <ul class="links inline"><li class="node-readmore"><a href="/dept/lcr/news/study-reveals-cause-different-outcomes-patients-experience-early-and-late-relapse-diffuse" rel="tag" title="Study reveals cause for different outcomes for patients that experience early and late relapse of diffuse large B-cell lymphoma" hreflang="en">More Info<span class="visually-hidden"> about Study reveals cause for different outcomes for patients that experience early and late relapse of diffuse large B-cell lymphoma</span></a></li></ul> </div> </article> </div></div> </section> </section> <section class="views-element-container block block--views-blocklabs-block-1 block--research-labs-amp-principal-investigators block-views-block-labs-block-1" id="block-views-block-labs-block-1"> <h2 class="section__title">Research Labs & Principal Investigators</h2> <div><div class="js-view-dom-id-d4f7e0e1e1eccc9f744fc74e5f87aea4921fd5ce4ff7d84f4407ca3f600ee35c view view--labs"> <div class="views-view-grid view--labs cols-4"> <article class="node lab teaser"> <a href="/dept/lcr/labs/scott-lab"><figure> <img loading="lazy" src="/dept/lcr/sites/lymphoidcancer/files/styles/profile/public/2019-10/DavidScott_headshot.jpg?itok=QEBvk6Qp" width="580" height="460" alt="" /> </figure> </a> <h2 class="node__title"> <a href="/dept/lcr/labs/scott-lab" rel="bookmark" ><span>Scott Lab</span> </a> </h2> </article> <article class="node lab teaser"> <a href="/dept/lcr/labs/steidl-lab"><figure> <img loading="lazy" src="/dept/lcr/sites/lymphoidcancer/files/styles/profile/public/2019-09/Christian_Steidl__03909.jpg?itok=RAxKkwdv" width="580" height="460" alt="" /> </figure> </a> <h2 class="node__title"> <a href="/dept/lcr/labs/steidl-lab" rel="bookmark" ><span>Steidl Lab</span> </a> </h2> </article> <article class="node lab teaser"> <a href="/dept/lcr/labs/venturutti-lab"><figure> <img loading="lazy" src="/dept/lcr/sites/lymphoidcancer/files/styles/profile/public/2022-06/LVshot.jpg?itok=AmkraLET" width="580" height="460" alt="" /> </figure> </a> <h2 class="node__title"> <a href="/dept/lcr/labs/venturutti-lab" rel="bookmark" ><span>Venturutti Lab </span> </a> </h2> </article> </div> </div> </div> </section> <section class="views-element-container block block--views-blockpublications-block-1 block--recent-publications block-views-block-publications-block-1" id="block-views-block-publications-block-1"> <h2 class="section__title">Recent Publications</h2> <div><div class="js-view-dom-id-f9f3ed2734716de82dbfe24bf3824b4e5c2599ab20ab7aa683624cafeeb320f6 view view--publications"> <div class="views-view-grid view--publications cols-3"> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/36001803" target="_blank" rel="bookmark"><span>Genomic Profiling for Clinical Decision Making in Lymphoid Neoplasms</span> </a></p> <div class="field field--field_journal">Blood, 2022</div> <div class="field field--field_authors">Laurence de Leval, Ash A Alizadeh, P Leif Bergsagel, Elias Campo, Andrew John Davies, Ahmet Dogan, Jude Fitzgibbon, Steven M. Horwitz, Ari M. Melnick, William George Morice, Ryan D Morin, Bertrand Nadel, Stefano A Pileri, Professor, Richard Rosenquist, Davide Rossi, Itziar Salaverria, Christian Steidl, Steven P Treon, Andrew D. Zelenetz, Ranjana Advani, Carl E Allen, Stephen M. Ansell, Wing C. Chan, James R. Cook, Lucy B Cook, Francesco d'Amore, Stefan Dirnhofer, Martin Dreyling, Kieron Dunleavy, Andrew Feldman, Falko Fend, Philippe GAULARD, Paolo Ghia, John G Gribben, Olivier Hermine, Daniel J Hodson, Eric D. Hsi, Giorgio GA Inghirami, Elaine S. Jaffe, Kennosuke Karube, Keisuke Kataoka, Wolfram Klapper, Won Seog Kim, Rebecca L King, Young Hyeh Ko, Ann S. LaCasce, Georg Lenz, Iñaki Martin-Subero, Miguel A Piris, Stefania Pittaluga, Laura Pasqualucci, Leticia Quintanilla-Martinez, Scott J. Rodig, Andreas Rosenwald, Gilles A. Salles, Jesus San-Miguel, Kerry J. Savage, Laurie H. Sehn, Gianpietro Semenzato, Louis M Staudt, Steven Howard Swerdlow, Constantine S. Tam, Judith Trotman, Julie Vose, Oliver Weigert, Wyndham H. Wilson, Jane N Winter, Catherine J. Wu, Pier Luigi Zinzani, Emanuele Zucca, Adam Bagg, David W. W. Scott</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/36001803" target="_blank">Learn More</a></div> </article> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/36302166" target="_blank" rel="bookmark"><span>Molecular Determinants of Clinical Outcomes In a Real-World Diffuse Large B-cell Lymphoma Population</span> </a></p> <div class="field field--field_journal">Blood, 2022</div> <div class="field field--field_authors">Waleed Alduaij, Brett J Collinge, Susana Ben-Neriah, Aixiang Jiang, Laura K Hilton, Merrill Boyle, Barbara Meissner, Lauren C. Chong, Tomoko Miyata-Takata, Graham W. Slack, Pedro Farinha, Jeffrey W Craig, Andrew Lytle, Kerry J. Savage, Diego Villa, Alina S. Gerrie, Ciara L. Freeman, Randy D. Gascoyne, Joseph M Connors, Ryan D Morin, Laurie H. Sehn, Andrew J Mungall, Christian Steidl, David W. Scott</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/36302166" target="_blank">Learn More</a></div> </article> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/36264161" target="_blank" rel="bookmark"><span>An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas</span> </a></p> <div class="field field--field_journal">Cancer Discovery, 2023</div> <div class="field field--field_authors">Venturutti L*, Rivas MA, Pelzer BW, Flümann R, Hansen J, Karagiannidis I, Xia M, McNally DR, Isshiki Y, Lytle A, Teater M, Chin CR, Meydan C, Knittel G, Ricker E, Mason CE, Ye X, Pan-Hammarström Q, Steidl C, Scott DW, Reinhardt HC, Pernis AB, Béguelin W, Melnick AM. *Co-corresponding author.</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/36264161" target="_blank">Learn More</a></div> </article> </div> <nav role="navigation" aria-labelledby="pagination-heading"> <h4 class="visually-hidden">Pagination</h4> <ul class="js-pager__items pager__items mini"> <li> <a href="/dept/lcr/lymphoid-cancer-research?page=1" title="Go to next page" rel="next"> <span class="visually-hidden">Next page</span> <span aria-hidden="true">››</span> </a> </li> </ul> </nav> </div> </div> </section> </div> </section> </div> <a class="top" href="#main-content">Back to top</a> </main> <section class="region region__cta"> <div class="region__cta--inner region--inner"> <section id="block-sitecalltoaction" class="block block--block-contenta8a59224-4648-42d5-b71c-294b3c630d8a block-sitecalltoaction"> <div class="field field--body"><p>BC Cancer Foundation is the fundraising partner of BC Cancer, which includes BC Cancer Research. Together with our donors, we are changing cancer outcomes for British Columbians by funding innovative research and personalized treatment and care.</p> <p><a class="button" href="https://bccancerfoundation.com/donations/general-donation-form/?s_src=BCCRCFooter" target="_blank">Donate Today</a></p></div> </section> </div> </section> <footer class="page" role="contentinfo"> <section class="region region__footer"> <div class="region__footer--inner region--inner"> <section id="block-bccrc-branding" class="block block--system-branding-block block-bccrc-branding"> <a href="/dept/lcr/" title="Home" rel="home"> <img src="/dept/lcr/sites/lymphoidcancer/files/BCClogo_Research_LymphoidCancer_RGB.png" alt="Home" /> </a> </section> <section id="block-contactus" class="block block--block-content2314a90f-9af6-4a1e-8cf5-6a294688e075 block--contact-us block-contactus"> <h2 class="section__title">Contact Us</h2> <div class="field field--body"><p>BC Cancer Research Institute<br> 675 West 10th Avenue<br> Vancouver, BC V5Z 1L3</p> <p>604 675 8000</p> <p>Toll Free: 1 888 675 8001</p></div> </section> <section id="block-followus" class="block block--block-content06fb6d8a-948b-4134-bf4f-c16a4f797215 block--follow-us block-followus"> <h2 class="section__title">Follow Us</h2> <div class="field field--body"><p><a class="fa fa-linkedin" href="https://www.linkedin.com/company/bc-cancer/"> </a><a class="fa fa-twitter" href="https://twitter.com/BCCancer"> </a><a class="fa fa-instagram" href="https://www.instagram.com/bccancer/"> </a></p></div> </section> <section id="block-phsa" class="block block--block-contentc5694593-5e25-4c72-b214-18cb9fbcec9e block-phsa"> <div class="field field--body"><p><a href="http://www.phsa.ca" target="_blank"><img alt="PHSA" src="https://www.bccrc.ca/dept/lcr/sites/lymphoidcancer/files/PHSA-logo.svg"></a></p></div> </section> </div> </section> </footer> <section class="region region__copyright"> <div class="region__copyright--inner region--inner"> <nav role="navigation" aria-labelledby="block-bccrc-footer-menu" id="block-bccrc-footer"> <h2 class="visually-hidden" id="block-bccrc-footer-menu">Footer menu</h2> <ul class="menu"> <li class="menu-item"> <a href="http://www.phsa.ca/privacy">Privacy Policy</a> </li> <li>Copyright © BC Cancer. 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