CINXE.COM
(PDF) Detection of physiological concentrations of cortisol and cortisone in human hair | Bertrand Ludes - Academia.edu
<!DOCTYPE html> <html > <head> <meta charset="utf-8"> <meta rel="search" type="application/opensearchdescription+xml" href="/open_search.xml" title="Academia.edu"> <meta content="width=device-width, initial-scale=1" name="viewport"> <meta name="google-site-verification" content="bKJMBZA7E43xhDOopFZkssMMkBRjvYERV-NaN4R6mrs"> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="HLR1F7AjYm628TmfQE7W1a2kTZFLKNgkT/79zZ1hf/X6YtHE9tgwNsIp7ulKJzWgloaXfB0VwM29uE2KS7RAXw==" /> <meta name="citation_title" content="Detection of physiological concentrations of cortisol and cortisone in human hair" /> <meta name="citation_publication_date" content="2004/01/01" /> <meta name="citation_journal_title" content="Clinical Biochemistry" /> <meta name="citation_author" content="Bertrand Ludes" /> <meta name="twitter:card" content="summary" /> <meta name="twitter:url" content="https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair" /> <meta name="twitter:title" content="Detection of physiological concentrations of cortisol and cortisone in human hair" /> <meta name="twitter:description" content="Academia.edu is a platform for academics to share research papers." /> <meta name="twitter:image" content="http://a.academia-assets.com/images/twitter-card.jpeg" /> <meta property="fb:app_id" content="2369844204" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair" /> <meta property="og:title" content="Detection of physiological concentrations of cortisol and cortisone in human hair" /> <meta property="og:image" content="http://a.academia-assets.com/images/open-graph-icons/fb-paper.gif" /> <meta property="og:description" content="Detection of physiological concentrations of cortisol and cortisone in human hair" /> <meta property="article:author" content="https://independent.academia.edu/BertrandLudes" /> <meta name="description" content="Detection of physiological concentrations of cortisol and cortisone in human hair" /> <title>(PDF) Detection of physiological concentrations of cortisol and cortisone in human hair | Bertrand Ludes - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '49879c2402910372f4abc62630a427bbe033d190'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732511506000); window.Aedu.timeDifference = new Date().getTime() - 1732511506000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":null,"author":[{"@context":"https://schema.org","@type":"Person","name":"Bertrand Ludes"}],"contributor":[],"dateCreated":"2015-05-19","dateModified":null,"datePublished":"2004-01-01","headline":"Detection of physiological concentrations of cortisol and cortisone in human hair","inLanguage":"en","keywords":["Mass Spectrometry","Clinical Biochemistry","Adolescent","Cortisol","Humans","Child","Hair","Female","Male","Aged","Middle Aged","Adult","Liquid Chromatography","Sex Factors","Time Factors","Ether","Gas Chromatography/mass Spectrometry","Age Factors","Cortisone","Glucocorticoids"],"locationCreated":null,"publication":"Clinical Biochemistry","publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/single_work_page/loswp-352e32ba4e89304dc0b4fa5b3952eef2198174c54cdb79066bc62e91c68a1a91.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/body-8d679e925718b5e8e4b18e9a4fab37f7eaa99e43386459376559080ac8f2856a.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-3cea6e0ad4715ed965c49bfb15dedfc632787b32ff6d8c3a474182b231146ab7.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/text_button-73590134e40cdb49f9abdc8e796cc00dc362693f3f0f6137d6cf9bb78c318ce7.css" /><link crossorigin="" href="https://fonts.gstatic.com/" rel="preconnect" /><link href="https://fonts.googleapis.com/css2?family=DM+Sans:ital,opsz,wght@0,9..40,100..1000;1,9..40,100..1000&family=Gupter:wght@400;500;700&family=IBM+Plex+Mono:wght@300;400&family=Material+Symbols+Outlined:opsz,wght,FILL,GRAD@20,400,0,0&display=swap" rel="stylesheet" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/common-10fa40af19d25203774df2d4a03b9b5771b45109c2304968038e88a81d1215c5.css" /> </head> <body> <div id='react-modal'></div> <div class="js-upgrade-ie-banner" style="display: none; text-align: center; padding: 8px 0; background-color: #ebe480;"><p style="color: #000; font-size: 12px; margin: 0 0 4px;">Academia.edu no longer supports Internet Explorer.</p><p style="color: #000; font-size: 12px; margin: 0;">To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to <a href="https://www.academia.edu/upgrade-browser">upgrade your browser</a>.</p></div><script>// Show this banner for all versions of IE if (!!window.MSInputMethodContext || /(MSIE)/.test(navigator.userAgent)) { document.querySelector('.js-upgrade-ie-banner').style.display = 'block'; }</script> <div class="bootstrap login"><div class="modal fade login-modal" id="login-modal"><div class="login-modal-dialog modal-dialog"><div class="modal-content"><div class="modal-header"><button class="close close" data-dismiss="modal" type="button"><span aria-hidden="true">×</span><span class="sr-only">Close</span></button><h4 class="modal-title text-center"><strong>Log In</strong></h4></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><button class="btn btn-fb btn-lg btn-block btn-v-center-content" id="login-facebook-oauth-button"><svg style="float: left; width: 19px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="facebook-square" class="svg-inline--fa fa-facebook-square fa-w-14" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path fill="currentColor" d="M400 32H48A48 48 0 0 0 0 80v352a48 48 0 0 0 48 48h137.25V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.27c-30.81 0-40.42 19.12-40.42 38.73V256h68.78l-11 71.69h-57.78V480H400a48 48 0 0 0 48-48V80a48 48 0 0 0-48-48z"></path></svg><small><strong>Log in</strong> with <strong>Facebook</strong></small></button><br /><button class="btn btn-google btn-lg btn-block btn-v-center-content" id="login-google-oauth-button"><svg style="float: left; width: 22px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="google-plus" class="svg-inline--fa fa-google-plus fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M256,8C119.1,8,8,119.1,8,256S119.1,504,256,504,504,392.9,504,256,392.9,8,256,8ZM185.3,380a124,124,0,0,1,0-248c31.3,0,60.1,11,83,32.3l-33.6,32.6c-13.2-12.9-31.3-19.1-49.4-19.1-42.9,0-77.2,35.5-77.2,78.1S142.3,334,185.3,334c32.6,0,64.9-19.1,70.1-53.3H185.3V238.1H302.2a109.2,109.2,0,0,1,1.9,20.7c0,70.8-47.5,121.2-118.8,121.2ZM415.5,273.8v35.5H380V273.8H344.5V238.3H380V202.8h35.5v35.5h35.2v35.5Z"></path></svg><small><strong>Log in</strong> with <strong>Google</strong></small></button><br /><style type="text/css">.sign-in-with-apple-button { width: 100%; height: 52px; border-radius: 3px; border: 1px solid black; cursor: pointer; }</style><script src="https://appleid.cdn-apple.com/appleauth/static/jsapi/appleid/1/en_US/appleid.auth.js" type="text/javascript"></script><div class="sign-in-with-apple-button" data-border="false" data-color="white" id="appleid-signin"><span ="Sign Up with Apple" class="u-fs11"></span></div><script>AppleID.auth.init({ clientId: 'edu.academia.applesignon', scope: 'name email', redirectURI: 'https://www.academia.edu/sessions', state: "089ecf3ea4c7a2574647f68fa83a80f70488d2f550f1bab7636ade0a44663439", });</script><script>// Hacky way of checking if on fast loswp if (window.loswp == null) { (function() { const Google = window?.Aedu?.Auth?.OauthButton?.Login?.Google; const Facebook = window?.Aedu?.Auth?.OauthButton?.Login?.Facebook; if (Google) { new Google({ el: '#login-google-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } if (Facebook) { new Facebook({ el: '#login-facebook-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } })(); }</script></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><div class="hr-heading login-hr-heading"><span class="hr-heading-text">or</span></div></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><form class="js-login-form" action="https://www.academia.edu/sessions" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="BmVT09jlDQH4lJikVXKsWJonNtTxNA8+XMn1Hr+UMSPgs/cAnh5fWYxMT9JfG08toQXsOacJF9euj0VZaUEOiQ==" autocomplete="off" /><div class="form-group"><label class="control-label" for="login-modal-email-input" style="font-size: 14px;">Email</label><input class="form-control" id="login-modal-email-input" name="login" type="email" /></div><div class="form-group"><label class="control-label" for="login-modal-password-input" style="font-size: 14px;">Password</label><input class="form-control" id="login-modal-password-input" name="password" type="password" /></div><input type="hidden" name="post_login_redirect_url" id="post_login_redirect_url" value="https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair" autocomplete="off" /><div class="checkbox"><label><input type="checkbox" name="remember_me" id="remember_me" value="1" checked="checked" /><small style="font-size: 12px; margin-top: 2px; display: inline-block;">Remember me on this computer</small></label></div><br><input type="submit" name="commit" value="Log In" class="btn btn-primary btn-block btn-lg js-login-submit" data-disable-with="Log In" /></br></form><script>typeof window?.Aedu?.recaptchaManagedForm === 'function' && window.Aedu.recaptchaManagedForm( document.querySelector('.js-login-form'), document.querySelector('.js-login-submit') );</script><small style="font-size: 12px;"><br />or <a data-target="#login-modal-reset-password-container" data-toggle="collapse" href="javascript:void(0)">reset password</a></small><div class="collapse" id="login-modal-reset-password-container"><br /><div class="well margin-0x"><form class="js-password-reset-form" action="https://www.academia.edu/reset_password" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="OM+miBvOnpSgNkW/IfL03wNFQU/5UuLARWeoVRRagsfeGQJbXTXMzNTukskrmxeqOGeboq9v+im3IRgSwo+9bQ==" autocomplete="off" /><p>Enter the email address you signed up with and we'll email you a reset link.</p><div class="form-group"><input class="form-control" name="email" type="email" /></div><input class="btn btn-primary btn-block g-recaptcha js-password-reset-submit" data-sitekey="6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj" type="submit" value="Email me a link" /></form></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/collapse-45805421cf446ca5adf7aaa1935b08a3a8d1d9a6cc5d91a62a2a3a00b20b3e6a.js"], function() { // from javascript_helper.rb $("#login-modal-reset-password-container").on("shown.bs.collapse", function() { $(this).find("input[type=email]").focus(); }); }); </script> </div></div></div><div class="modal-footer"><div class="text-center"><small style="font-size: 12px;">Need an account? <a rel="nofollow" href="https://www.academia.edu/signup">Click here to sign up</a></small></div></div></div></div></div></div><script>// If we are on subdomain or non-bootstrapped page, redirect to login page instead of showing modal (function(){ if (typeof $ === 'undefined') return; var host = window.location.hostname; if ((host === $domain || host === "www."+$domain) && (typeof $().modal === 'function')) { $("#nav_log_in").click(function(e) { // Don't follow the link and open the modal e.preventDefault(); $("#login-modal").on('shown.bs.modal', function() { $(this).find("#login-modal-email-input").focus() }).modal('show'); }); } })()</script> <div id="fb-root"></div><script>window.fbAsyncInit = function() { FB.init({ appId: "2369844204", version: "v8.0", status: true, cookie: true, xfbml: true }); // Additional initialization code. if (window.InitFacebook) { // facebook.ts already loaded, set it up. window.InitFacebook(); } else { // Set a flag for facebook.ts to find when it loads. window.academiaAuthReadyFacebook = true; } };</script> <div id="google-root"></div><script>window.loadGoogle = function() { if (window.InitGoogle) { // google.ts already loaded, set it up. window.InitGoogle("331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"); } else { // Set a flag for google.ts to use when it loads. window.GoogleClientID = "331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"; } };</script> <div class="header--container" id="main-header-container"><div class="header--inner-container header--inner-container-ds2"><div class="header-ds2--left-wrapper"><div class="header-ds2--left-wrapper-inner"><a data-main-header-link-target="logo_home" href="https://www.academia.edu/"><img class="hide-on-desktop-redesign" style="height: 24px; width: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015-A.svg" width="24" height="24" /><img width="145.2" height="18" class="hide-on-mobile-redesign" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015.svg" /></a><div class="header--search-container header--search-container-ds2"><form class="js-SiteSearch-form select2-no-default-pills" action="https://www.academia.edu/search" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><svg style="width: 14px; height: 14px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="search" class="header--search-icon svg-inline--fa fa-search fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M505 442.7L405.3 343c-4.5-4.5-10.6-7-17-7H372c27.6-35.3 44-79.7 44-128C416 93.1 322.9 0 208 0S0 93.1 0 208s93.1 208 208 208c48.3 0 92.7-16.4 128-44v16.3c0 6.4 2.5 12.5 7 17l99.7 99.7c9.4 9.4 24.6 9.4 33.9 0l28.3-28.3c9.4-9.4 9.4-24.6.1-34zM208 336c-70.7 0-128-57.2-128-128 0-70.7 57.2-128 128-128 70.7 0 128 57.2 128 128 0 70.7-57.2 128-128 128z"></path></svg><input class="header--search-input header--search-input-ds2 js-SiteSearch-form-input" data-main-header-click-target="search_input" name="q" placeholder="Search" type="text" /></form></div></div></div><nav class="header--nav-buttons header--nav-buttons-ds2 js-main-nav"><a class="ds2-5-button ds2-5-button--secondary js-header-login-url header-button-ds2 header-login-ds2 hide-on-mobile-redesign" href="https://www.academia.edu/login" rel="nofollow">Log In</a><a class="ds2-5-button ds2-5-button--secondary header-button-ds2 hide-on-mobile-redesign" href="https://www.academia.edu/signup" rel="nofollow">Sign Up</a><button class="header--hamburger-button header--hamburger-button-ds2 hide-on-desktop-redesign js-header-hamburger-button"><div class="icon-bar"></div><div class="icon-bar" style="margin-top: 4px;"></div><div class="icon-bar" style="margin-top: 4px;"></div></button></nav></div><ul class="header--dropdown-container js-header-dropdown"><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/login" rel="nofollow">Log In</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/signup" rel="nofollow">Sign Up</a></li><li class="header--dropdown-row js-header-dropdown-expand-button"><button class="header--dropdown-button">more<svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="caret-down" class="header--dropdown-button-icon svg-inline--fa fa-caret-down fa-w-10" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 320 512"><path fill="currentColor" d="M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z"></path></svg></button></li><li><ul class="header--expanded-dropdown-container"><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/about">About</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/press">Press</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://medium.com/@academia">Blog</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/documents">Papers</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/terms">Terms</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/privacy">Privacy</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/copyright">Copyright</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://www.academia.edu/hiring"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="briefcase" class="header--dropdown-row-icon svg-inline--fa fa-briefcase fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M320 336c0 8.84-7.16 16-16 16h-96c-8.84 0-16-7.16-16-16v-48H0v144c0 25.6 22.4 48 48 48h416c25.6 0 48-22.4 48-48V288H320v48zm144-208h-80V80c0-25.6-22.4-48-48-48H176c-25.6 0-48 22.4-48 48v48H48c-25.6 0-48 22.4-48 48v80h512v-80c0-25.6-22.4-48-48-48zm-144 0H192V96h128v32z"></path></svg>We're Hiring!</a></li><li class="header--dropdown-row"><a class="header--dropdown-link" href="https://support.academia.edu/"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="question-circle" class="header--dropdown-row-icon svg-inline--fa fa-question-circle fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M504 256c0 136.997-111.043 248-248 248S8 392.997 8 256C8 119.083 119.043 8 256 8s248 111.083 248 248zM262.655 90c-54.497 0-89.255 22.957-116.549 63.758-3.536 5.286-2.353 12.415 2.715 16.258l34.699 26.31c5.205 3.947 12.621 3.008 16.665-2.122 17.864-22.658 30.113-35.797 57.303-35.797 20.429 0 45.698 13.148 45.698 32.958 0 14.976-12.363 22.667-32.534 33.976C247.128 238.528 216 254.941 216 296v4c0 6.627 5.373 12 12 12h56c6.627 0 12-5.373 12-12v-1.333c0-28.462 83.186-29.647 83.186-106.667 0-58.002-60.165-102-116.531-102zM256 338c-25.365 0-46 20.635-46 46 0 25.364 20.635 46 46 46s46-20.636 46-46c0-25.365-20.635-46-46-46z"></path></svg>Help Center</a></li><li class="header--dropdown-row js-header-dropdown-collapse-button"><button class="header--dropdown-button">less<svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="caret-up" class="header--dropdown-button-icon svg-inline--fa fa-caret-up fa-w-10" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 320 512"><path fill="currentColor" d="M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z"></path></svg></button></li></ul></li></ul></div> <script src="//a.academia-assets.com/assets/webpack_bundles/fast_loswp-bundle-bf3d831cde46cd0e142f29f81a3fc4ce5ab45a404c10c12a480e83de68aff851.js" defer="defer"></script><script>window.loswp = {}; window.loswp.author = 31283622; window.loswp.bulkDownloadFilterCounts = {}; window.loswp.hasDownloadableAttachment = true; window.loswp.hasViewableAttachments = true; // TODO: just use routes for this window.loswp.loginUrl = "https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F12457883%2FDetection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair%3Fauto%3Ddownload"; window.loswp.translateUrl = "https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F12457883%2FDetection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":46169359,"identifier":"Attachment_46169359","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":12457883,"created_at":"2015-05-19T00:52:05.708-07:00","from_world_paper_id":136533014,"updated_at":"2024-11-18T01:18:42.037-08:00","_data":{"grobid_abstract":"Objective: Since the 1960s, glucocorticoids are used by athletes to improve their performances. Their use is restricted in sports. Hair can document chronic abuse and can be therefore a complementary matrix for doping control. We have developed a new extraction, purification, and separation technique using liquid chromatography and mass spectrometry for the identification and quantification of two endogenous glucocorticoids: cortisol and cortisone.","publication_date":"2004,,","publication_name":"Clinical Biochemistry","grobid_abstract_attachment_id":"46169359"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Detection of physiological concentrations of cortisol and cortisone in human hair","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [31283622]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":46169359,"attachmentType":"pdf"}"><img alt="First page of “Detection of physiological concentrations of cortisol and cortisone in human hair”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/46169359/mini_magick20180819-22053-oqm3hl.png?1534666384" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Detection of physiological concentrations of cortisol and cortisone in human hair</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="31283622" href="https://independent.academia.edu/BertrandLudes"><img alt="Profile image of Bertrand Ludes" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Bertrand Ludes</a></div><p class="ds-work-card--detail ds2-5-body-sm">2004, Clinical Biochemistry</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":46169359,"attachmentType":"pdf","workUrl":"https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":46169359,"attachmentType":"pdf","workUrl":"https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="46169359" data-landing_url="https://www.academia.edu/12457883/Detection_of_physiological_concentrations_of_cortisol_and_cortisone_in_human_hair" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="48191846" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/48191846/An_assessment_of_cortisol_analysis_in_hair_and_its_clinical_applications">An assessment of cortisol analysis in hair and its clinical applications</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32710843" href="https://independent.academia.edu/MichaelRieder">Michael Rieder</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Forensic Science International, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"An assessment of cortisol analysis in hair and its clinical applications","attachmentId":66946910,"attachmentType":"pdf","work_url":"https://www.academia.edu/48191846/An_assessment_of_cortisol_analysis_in_hair_and_its_clinical_applications","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/48191846/An_assessment_of_cortisol_analysis_in_hair_and_its_clinical_applications"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="23715251" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23715251/Toward_Standardization_of_Hair_Cortisol_Measurement_Results_of_the_First_International_Inter_laboratory_Round_Robin">Toward Standardization of Hair Cortisol Measurement; Results of the First International Inter-laboratory Round Robin</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33049582" href="https://independent.academia.edu/ElisabethVanRossum">Elisabeth Van Rossum</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Therapeutic Drug Monitoring, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Toward Standardization of Hair Cortisol Measurement; Results of the First International Inter-laboratory Round Robin","attachmentId":44137809,"attachmentType":"pdf","work_url":"https://www.academia.edu/23715251/Toward_Standardization_of_Hair_Cortisol_Measurement_Results_of_the_First_International_Inter_laboratory_Round_Robin","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23715251/Toward_Standardization_of_Hair_Cortisol_Measurement_Results_of_the_First_International_Inter_laboratory_Round_Robin"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="77403752" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/77403752/Hair_as_a_Specimen_to_Determine_the_Concentration_of_Cortisol_Levels_in_Individuals_that_have_Performed_Physical_Activity">Hair as a Specimen to Determine the Concentration of Cortisol Levels in Individuals that have Performed Physical Activity</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="56705688" href="https://ufba.academia.edu/LaisaPaineirasDomingos">Profa Dra Laisa L Paineiras-Domingos</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Trichology and Cosmetology – Open Journal, 2018</p><p class="ds-related-work--abstract ds2-5-body-sm">Introduction The physical inactivity has been identified as the fourth leading risk factor for mortality in the world. Physical activity may exert beneficial influence on the cardiovascular system, besides to bring benefits to the lipid metabolism, the increase of the lean mass, and the increase of the basal metabolism. As a response of the physical activity, the concentration of several hormones is altered, as the cortisol. Different specimens are used to determination of concentration of the cortisol, like saliva, urine, blood samples and hair. The aim of this narrative review is to present scientific information about the use of the hair to evaluate the concentration of cortisol in individuals that have performed physical activity. Materials and Methods Publications were accessed in the database PubMed September 12th, 2018 using the keywords hair and “physical activity” and cortisol. Results In general, it was found that the hair can be used to determine the concentration of cort...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hair as a Specimen to Determine the Concentration of Cortisol Levels in Individuals that have Performed Physical Activity","attachmentId":84779562,"attachmentType":"pdf","work_url":"https://www.academia.edu/77403752/Hair_as_a_Specimen_to_Determine_the_Concentration_of_Cortisol_Levels_in_Individuals_that_have_Performed_Physical_Activity","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/77403752/Hair_as_a_Specimen_to_Determine_the_Concentration_of_Cortisol_Levels_in_Individuals_that_have_Performed_Physical_Activity"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="113655874" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/113655874/Hair_cortisol_analysis_An_update_on_methodological_considerations_and_clinical_applications">Hair cortisol analysis: An update on methodological considerations and clinical applications</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36470223" href="https://independent.academia.edu/StanVanUum">Stan Van Uum</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical biochemistry, 2018</p><p class="ds-related-work--abstract ds2-5-body-sm">Hair cortisol analysis is increasingly being appreciated and applied in both research and medicine, aiding endocrinologists with diagnosis. We provide an overview of hair cortisol research in general and an update on methodological considerations including the incorporation of cortisol into hair, hair growth rates, and sampling procedures, mincing vs. grinding of samples during preparation for extraction, various extraction protocols, and quantification techniques. We compare the clinical utility and application of hair cortisol with traditional methods of measurement while acknowledging the limitations of analysis including variations in hair growth parameters. We explore the value of hair cortisol in cases of Cushing syndrome (particularly Cyclical Cushing), Adrenal insufficiency (including Addison&#39;s disease), therapy monitoring, cardiovascular disease, stress, and mental illness. Hair cortisol provides a unique objective biomarker for the analysis of endogenous cortisol level...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hair cortisol analysis: An update on methodological considerations and clinical applications","attachmentId":110560284,"attachmentType":"pdf","work_url":"https://www.academia.edu/113655874/Hair_cortisol_analysis_An_update_on_methodological_considerations_and_clinical_applications","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/113655874/Hair_cortisol_analysis_An_update_on_methodological_considerations_and_clinical_applications"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="23715261" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23715261/Clinical_applications_of_cortisol_measurements_in_hair">Clinical applications of cortisol measurements in hair</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33049582" href="https://independent.academia.edu/ElisabethVanRossum">Elisabeth Van Rossum</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European journal of endocrinology / European Federation of Endocrine Societies, 2015</p><p class="ds-related-work--abstract ds2-5-body-sm">Cortisol measurements in blood, saliva, and urine are frequently used to examine the hypothalamus-pituitary-adrenal axis in clinical practice and in research. However, cortisol levels are subject to variations due to acute stress, the diurnal rhythm and pulsatile secretion. Cortisol measurements in body fluids are not always a reflection of long-term cortisol exposure. The analysis of cortisol in scalp hair is a relatively novel method to measure cumulative cortisol exposure over months up to years. Over the past years, hair cortisol concentrations (HCC) have been examined in association with a large number of somatic and mental health conditions. HCC can be used to evaluate disturbances of the HPA axis, including Cushing&#39;s syndrome, and to evaluate hydrocortisone treatment. Using HCC, retrospective timelines of cortisol exposure can be created, which can be of value in diagnosing cyclic hypercortisolism. HCC have also been shown to increase with psychological stressors, includi...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Clinical applications of cortisol measurements in hair","attachmentId":44137817,"attachmentType":"pdf","work_url":"https://www.academia.edu/23715261/Clinical_applications_of_cortisol_measurements_in_hair","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23715261/Clinical_applications_of_cortisol_measurements_in_hair"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="70600625" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/70600625/Validity_and_reliability_of_method_used_to_analyse_hair_cortisol_concentration">Validity and reliability of method used to analyse hair cortisol concentration</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="185230481" href="https://tudublin.academia.edu/JordanReid">Jordan Reid</a></div><p class="ds-related-work--metadata ds2-5-body-xs">F1000Research</p><p class="ds-related-work--abstract ds2-5-body-sm">Hair cortisol analysis is a method of analysing the stress hormone cortisol that offers great potential for helping researchers understand the long-term impact of stress and distress on the body. Hair analysis not only provides an excellent method of studying the average production of cortisol over weeks and months, but also the potential to understand cortisol levels several months before the hair was collected. Whilst research with hair samples for cortisol analysis is a fast-developing field, there has been less analysis of the methods used to analyse hair cortisol. We report two studies where the novel hair analysis method developed at the Anglia Ruskin university (ARU) Biomarker Laboratory was tested for reliability and validity. In study 1, 32 participants provided hair samples for an examination of the reproducibility of the hair cortisol analysis method. In study 2, 53 participants provided a hair sample cut from the scalp, and the methanol that the cortisol was extracted in...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Validity and reliability of method used to analyse hair cortisol concentration","attachmentId":80284640,"attachmentType":"pdf","work_url":"https://www.academia.edu/70600625/Validity_and_reliability_of_method_used_to_analyse_hair_cortisol_concentration","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/70600625/Validity_and_reliability_of_method_used_to_analyse_hair_cortisol_concentration"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="117019606" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/117019606/Hair_Cortisol_Measurement_by_an_Automated_Method">Hair Cortisol Measurement by an Automated Method</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="303965260" href="https://independent.academia.edu/AyelenBalbi">Ayelen Balbi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Scientific Reports, 2019</p><p class="ds-related-work--abstract ds2-5-body-sm">We present the development of the first procedure for hair cortisol measurement through an automated method. Hair samples were obtained from 286 individuals. After cortisol extraction, samples were measured in a Siemens Immulite 2000 (Gwynedd, UK) automated chemoluminiscent immunoassay analyzer. Normal reference values were obtained from hair cortisol levels measured in 213 healthy individuals with low levels of stress. Hair cortisol concentration median was 55 pg/mg hair (2.5–97.5 percentile (40–128)) in healthy individuals with low levels of stress and 250 pg/mg hair (range 182–520) in stressed individuals. No significant differences were observed in hair cortisol levels between subjects with and without dye (40 (40–107) and 40 (40–155) pg/mg hair, respectively; p = 0.128). The novel procedure presented here shows an adequate analytical performance.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hair Cortisol Measurement by an Automated Method","attachmentId":112989966,"attachmentType":"pdf","work_url":"https://www.academia.edu/117019606/Hair_Cortisol_Measurement_by_an_Automated_Method","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/117019606/Hair_Cortisol_Measurement_by_an_Automated_Method"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="83304197" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/83304197/High_performance_liquid_chromatography_methods_for_the_analysis_of_endogenous_cortisol_and_cortisone_in_human_urine_comparison_of_mass_spectrometry_and_fluorescence_detection">High-performance liquid chromatography methods for the analysis of endogenous cortisol and cortisone in human urine: comparison of mass spectrometry and fluorescence detection</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="153864670" href="https://independent.academia.edu/MariolaKrzy%C5%9Bcin">Mariola Krzyścin</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of Clinical Biochemistry, 2019</p><p class="ds-related-work--abstract ds2-5-body-sm">Background The analysis of steroids in biological matrices is challenging. One can apply immunoassay as well as gas and liquid chromatography with various types of detection, depending on the available equipment and the experience of the analyst. The question is how the methods are interchangeable between themselves. Doubts were reported having compared immunoassays and chromatography-mass spectrometry, but there are scarce data on chromatographic methods with detection types other than mass spectrometry. Methods Here, we present the detailed comparison of two liquid chromatographic methods for the determination of free urinary cortisol and cortisone: one with fluorescence detection (high-performance liquid chromatography [HPLC-FLD]) and the other with tandem mass spectrometry (HPLC-MS/MS). The comparison was made with 199 human urine samples. The data analysis included Passing–Bablok and Deming regression, Bland–Altman test, Wilcoxon test, mountain plot and Lin’s concordance correl...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"High-performance liquid chromatography methods for the analysis of endogenous cortisol and cortisone in human urine: comparison of mass spectrometry and fluorescence detection","attachmentId":88694185,"attachmentType":"pdf","work_url":"https://www.academia.edu/83304197/High_performance_liquid_chromatography_methods_for_the_analysis_of_endogenous_cortisol_and_cortisone_in_human_urine_comparison_of_mass_spectrometry_and_fluorescence_detection","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/83304197/High_performance_liquid_chromatography_methods_for_the_analysis_of_endogenous_cortisol_and_cortisone_in_human_urine_comparison_of_mass_spectrometry_and_fluorescence_detection"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="77654112" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/77654112/Trends_in_Analysis_of_Cortisol_and_Its_Derivatives">Trends in Analysis of Cortisol and Its Derivatives</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="1072444" href="https://okcu.academia.edu/AliBoolani">Ali Boolani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Advances in experimental medicine and biology, 2019</p><p class="ds-related-work--abstract ds2-5-body-sm">Determination of concentration of cortisol in various biological fluids can provide extensive information about a person&#39;s health. Historically, cortisol and its derivatives were (and still are) determined using immunoaffinity-based methods such as colorimetric ELISA assay, chemiluminescent immunoassay, fluorescence assays, radioimmunoassay, electrochemiluminescence immunoassay, immunochromatographic test, or sensors and immunosensors. Recently, mass spectrometry (MS)-based methods started to be used in determination of cortisol and its derivatives. These MS methods are net superior to immunoaffinity-based assays, but are not easily applicable and are also time-consuming and price prohibitive. Furthermore the standard MS instruments used are triple quadrupole instruments. Here we review the literature on the MS and non-MS based methods for determination of cortisol and its derivatives and also explore the use of a less used quadrupole-time of flight instrument in determination o...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Trends in Analysis of Cortisol and Its Derivatives","attachmentId":84965869,"attachmentType":"pdf","work_url":"https://www.academia.edu/77654112/Trends_in_Analysis_of_Cortisol_and_Its_Derivatives","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/77654112/Trends_in_Analysis_of_Cortisol_and_Its_Derivatives"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="18442404" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/18442404/Cortisol_and_cortisone_analysis_in_serum_and_plasma_by_atmospheric_pressure_photoionization_tandem_mass_spectrometry">Cortisol and cortisone analysis in serum and plasma by atmospheric pressure photoionization tandem mass spectrometry</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38450035" href="https://independent.academia.edu/MarkKushnir">Mark Kushnir</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Biochemistry, 2004</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cortisol and cortisone analysis in serum and plasma by atmospheric pressure photoionization tandem mass spectrometry","attachmentId":40065897,"attachmentType":"pdf","work_url":"https://www.academia.edu/18442404/Cortisol_and_cortisone_analysis_in_serum_and_plasma_by_atmospheric_pressure_photoionization_tandem_mass_spectrometry","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/18442404/Cortisol_and_cortisone_analysis_in_serum_and_plasma_by_atmospheric_pressure_photoionization_tandem_mass_spectrometry"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":46169359,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":46169359,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_46169359" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="120363437" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/120363437/Radiolabel_validation_of_cortisol_in_the_hair_of_rhesus_monkeys">Radiolabel validation of cortisol in the hair of rhesus monkeys</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="104663" href="https://wisc.academia.edu/ToniZiegler">Toni Ziegler</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Psychoneuroendocrinology, 2018</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Radiolabel validation of cortisol in the hair of rhesus monkeys","attachmentId":115538706,"attachmentType":"pdf","work_url":"https://www.academia.edu/120363437/Radiolabel_validation_of_cortisol_in_the_hair_of_rhesus_monkeys","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/120363437/Radiolabel_validation_of_cortisol_in_the_hair_of_rhesus_monkeys"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="1" data-entity-id="101018876" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/101018876/Multi_matrix_assay_of_cortisol_cortisone_and_corticosterone_using_a_combined_MEPS_HPLC_procedure">Multi-matrix assay of cortisol, cortisone and corticosterone using a combined MEPS-HPLC procedure</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39616791" href="https://independent.academia.edu/LorenzoSomaini">Lorenzo Somaini</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Pharmaceutical and Biomedical Analysis, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Multi-matrix assay of cortisol, cortisone and corticosterone using a combined MEPS-HPLC procedure","attachmentId":101674265,"attachmentType":"pdf","work_url":"https://www.academia.edu/101018876/Multi_matrix_assay_of_cortisol_cortisone_and_corticosterone_using_a_combined_MEPS_HPLC_procedure","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/101018876/Multi_matrix_assay_of_cortisol_cortisone_and_corticosterone_using_a_combined_MEPS_HPLC_procedure"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="2" data-entity-id="118793027" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/118793027/Influence_of_external_factors_on_hair_cortisol_concentrations">Influence of external factors on hair cortisol concentrations</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="207120171" href="https://independent.academia.edu/ErichM%C3%B6stl">Erich Möstl</a></div><p class="ds-related-work--metadata ds2-5-body-xs">General and Comparative Endocrinology, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Influence of external factors on hair cortisol concentrations","attachmentId":114335065,"attachmentType":"pdf","work_url":"https://www.academia.edu/118793027/Influence_of_external_factors_on_hair_cortisol_concentrations","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/118793027/Influence_of_external_factors_on_hair_cortisol_concentrations"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="3" data-entity-id="94238465" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/94238465/Candidate_definitive_method_for_the_determination_of_cortisol_in_human_serum">Candidate definitive method for the determination of cortisol in human serum</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="94337830" href="https://independent.academia.edu/JosephJonckheere">Joseph Jonckheere</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Biological Mass Spectrometry, 1983</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Candidate definitive method for the determination of cortisol in human serum","attachmentId":96751263,"attachmentType":"pdf","work_url":"https://www.academia.edu/94238465/Candidate_definitive_method_for_the_determination_of_cortisol_in_human_serum","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/94238465/Candidate_definitive_method_for_the_determination_of_cortisol_in_human_serum"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="4" data-entity-id="65403280" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/65403280/Sample_pretreatment_procedure_for_routine_liquid_chromatographic_assay_of_serum_cortisol">Sample-pretreatment procedure for routine liquid chromatographic assay of serum cortisol</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32883272" href="https://uniroma1.academia.edu/GiulianaVinci">Giuliana Vinci</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Talanta, 1986</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Sample-pretreatment procedure for routine liquid chromatographic assay of serum cortisol","attachmentId":77015863,"attachmentType":"pdf","work_url":"https://www.academia.edu/65403280/Sample_pretreatment_procedure_for_routine_liquid_chromatographic_assay_of_serum_cortisol","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/65403280/Sample_pretreatment_procedure_for_routine_liquid_chromatographic_assay_of_serum_cortisol"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="5" data-entity-id="115701750" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/115701750/Hair_testing_for_cortisol_by_UPLC_MS_MS_in_a_family_External_cross_contamination_from_use_of_cortisol_cream">Hair testing for cortisol by UPLC–MS/MS in a family: External cross-contamination from use of cortisol cream</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38476187" href="https://independent.academia.edu/SysJohansen">Sys Johansen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Forensic Science International, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hair testing for cortisol by UPLC–MS/MS in a family: External cross-contamination from use of cortisol cream","attachmentId":112034826,"attachmentType":"pdf","work_url":"https://www.academia.edu/115701750/Hair_testing_for_cortisol_by_UPLC_MS_MS_in_a_family_External_cross_contamination_from_use_of_cortisol_cream","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/115701750/Hair_testing_for_cortisol_by_UPLC_MS_MS_in_a_family_External_cross_contamination_from_use_of_cortisol_cream"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="6" data-entity-id="81330274" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/81330274/Determination_of_Free_and_Total_Cortisol_in_Plasma_and_Urine_by_Liquid_Chromatography_Tandem_Mass_Spectrometry">Determination of Free and Total Cortisol in Plasma and Urine by Liquid Chromatography-Tandem Mass Spectrometry</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="223842949" href="https://independent.academia.edu/WeiliHuang">Weili Huang</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Therapeutic Drug Monitoring, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Determination of Free and Total Cortisol in Plasma and Urine by Liquid Chromatography-Tandem Mass Spectrometry","attachmentId":87411099,"attachmentType":"pdf","work_url":"https://www.academia.edu/81330274/Determination_of_Free_and_Total_Cortisol_in_Plasma_and_Urine_by_Liquid_Chromatography_Tandem_Mass_Spectrometry","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/81330274/Determination_of_Free_and_Total_Cortisol_in_Plasma_and_Urine_by_Liquid_Chromatography_Tandem_Mass_Spectrometry"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="7" data-entity-id="75423279" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/75423279/Assessing_cortisol_from_hair_samples_in_a_large_observational_cohort_The_Whitehall_II_study">Assessing cortisol from hair samples in a large observational cohort: The Whitehall II study</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="59812616" href="https://independent.academia.edu/JaneFerrie">Jane Ferrie</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Psychoneuroendocrinology, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Assessing cortisol from hair samples in a large observational cohort: The Whitehall II study","attachmentId":83198081,"attachmentType":"pdf","work_url":"https://www.academia.edu/75423279/Assessing_cortisol_from_hair_samples_in_a_large_observational_cohort_The_Whitehall_II_study","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/75423279/Assessing_cortisol_from_hair_samples_in_a_large_observational_cohort_The_Whitehall_II_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="8" data-entity-id="4364539" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/4364539/Cortisol_assays_and_diagnostic_laboratory_procedures_in_human_biological_fluids">Cortisol assays and diagnostic laboratory procedures in human biological fluids</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="5334748" href="https://libero.academia.edu/GiorgiaAntonelli">Giorgia Antonelli</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Biochemistry, 2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cortisol assays and diagnostic laboratory procedures in human biological fluids","attachmentId":49906867,"attachmentType":"pdf","work_url":"https://www.academia.edu/4364539/Cortisol_assays_and_diagnostic_laboratory_procedures_in_human_biological_fluids","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/4364539/Cortisol_assays_and_diagnostic_laboratory_procedures_in_human_biological_fluids"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="9" data-entity-id="80555992" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/80555992/A_validated_method_for_measurement_of_serum_total_serum_free_and_salivary_cortisol_using_high_performance_liquid_chromatography_coupled_with_high_resolutionESI_TOF_mass_spectrometry">A validated method for measurement of serum total, serum free, and salivary cortisol, using high-performance liquid chromatography coupled with high-resolutionESI-TOF mass spectrometry</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33009787" href="https://independent.academia.edu/EmeseMez%C5%91si">Emese Mezősi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Analytical and Bioanalytical Chemistry, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A validated method for measurement of serum total, serum free, and salivary cortisol, using high-performance liquid chromatography coupled with high-resolutionESI-TOF mass spectrometry","attachmentId":86898548,"attachmentType":"pdf","work_url":"https://www.academia.edu/80555992/A_validated_method_for_measurement_of_serum_total_serum_free_and_salivary_cortisol_using_high_performance_liquid_chromatography_coupled_with_high_resolutionESI_TOF_mass_spectrometry","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/80555992/A_validated_method_for_measurement_of_serum_total_serum_free_and_salivary_cortisol_using_high_performance_liquid_chromatography_coupled_with_high_resolutionESI_TOF_mass_spectrometry"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="10" data-entity-id="92848396" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/92848396/A_comprehensive_study_for_the_validation_of_a_LC_MS_MS_method_for_the_determination_of_free_and_total_forms_of_urinary_cortisol_and_its_metabolites">A comprehensive study for the validation of a LC–MS/MS method for the determination of free and total forms of urinary cortisol and its metabolites</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36211377" href="https://independent.academia.edu/AngelaCuzzola">Angela Cuzzola</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Pharmaceutical and Biomedical Analysis, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A comprehensive study for the validation of a LC–MS/MS method for the determination of free and total forms of urinary cortisol and its metabolites","attachmentId":95748382,"attachmentType":"pdf","work_url":"https://www.academia.edu/92848396/A_comprehensive_study_for_the_validation_of_a_LC_MS_MS_method_for_the_determination_of_free_and_total_forms_of_urinary_cortisol_and_its_metabolites","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/92848396/A_comprehensive_study_for_the_validation_of_a_LC_MS_MS_method_for_the_determination_of_free_and_total_forms_of_urinary_cortisol_and_its_metabolites"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="11" data-entity-id="26621099" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26621099/Development_of_a_rapid_assay_for_the_analysis_of_serum_cortisol_and_its_implementation_into_a_routine_service_laboratory">Development of a rapid assay for the analysis of serum cortisol and its implementation into a routine service laboratory</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50606273" href="https://independent.academia.edu/BrianKeevil">Brian Keevil</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of Clinical Biochemistry: An international journal of biochemistry and laboratory medicine, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Development of a rapid assay for the analysis of serum cortisol and its implementation into a routine service laboratory","attachmentId":46907152,"attachmentType":"pdf","work_url":"https://www.academia.edu/26621099/Development_of_a_rapid_assay_for_the_analysis_of_serum_cortisol_and_its_implementation_into_a_routine_service_laboratory","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/26621099/Development_of_a_rapid_assay_for_the_analysis_of_serum_cortisol_and_its_implementation_into_a_routine_service_laboratory"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="12" data-entity-id="28119165" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/28119165/Determination_of_urinary_free_cortisol_by_HPLC">Determination of urinary free cortisol by HPLC</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="52704028" href="https://independent.academia.edu/HeleneMarkkanen">Helene Markkanen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical chemistry, 1997</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Determination of urinary free cortisol by HPLC","attachmentId":48434819,"attachmentType":"pdf","work_url":"https://www.academia.edu/28119165/Determination_of_urinary_free_cortisol_by_HPLC","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/28119165/Determination_of_urinary_free_cortisol_by_HPLC"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="13" data-entity-id="67745438" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/67745438/Title_Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents_Running_title_Adaption_of_the_collection_protocol_for_hair_cortisol_determination">Title : Validation of an adapted procedure to collect hair for cortisol determination in adolescents Running title : Adaption of the collection protocol for hair cortisol determination</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33122434" href="https://umontreal.academia.edu/IsabelleOuelletmorin">Isabelle Ouellet-morin</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Title : Validation of an adapted procedure to collect hair for cortisol determination in adolescents Running title : Adaption of the collection protocol for hair cortisol determination","attachmentId":78459656,"attachmentType":"pdf","work_url":"https://www.academia.edu/67745438/Title_Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents_Running_title_Adaption_of_the_collection_protocol_for_hair_cortisol_determination","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/67745438/Title_Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents_Running_title_Adaption_of_the_collection_protocol_for_hair_cortisol_determination"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="14" data-entity-id="52915846" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/52915846/Measurement_of_Cortisol_in_Human_Plasma_and_Urine_by_Ultra_Performance_Liquid_Chromatography_Tandem_Mass_Spectrometry">Measurement of Cortisol in Human Plasma and Urine by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="47402553" href="https://independent.academia.edu/SyedAlvi3">Syed Alvi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Asian Journal of Pharmaceutical and Clinical Research</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Measurement of Cortisol in Human Plasma and Urine by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry","attachmentId":69946983,"attachmentType":"pdf","work_url":"https://www.academia.edu/52915846/Measurement_of_Cortisol_in_Human_Plasma_and_Urine_by_Ultra_Performance_Liquid_Chromatography_Tandem_Mass_Spectrometry","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/52915846/Measurement_of_Cortisol_in_Human_Plasma_and_Urine_by_Ultra_Performance_Liquid_Chromatography_Tandem_Mass_Spectrometry"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="15" data-entity-id="55421355" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/55421355/Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents">Validation of an adapted procedure to collect hair for cortisol determination in adolescents</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33122434" href="https://umontreal.academia.edu/IsabelleOuelletmorin">Isabelle Ouellet-morin</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Psychoneuroendocrinology, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Validation of an adapted procedure to collect hair for cortisol determination in adolescents","attachmentId":71298694,"attachmentType":"pdf","work_url":"https://www.academia.edu/55421355/Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/55421355/Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="16" data-entity-id="120368623" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/120368623/The_Detection_of_Cortisol_in_Human_Sweat">The Detection of Cortisol in Human Sweat</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32710843" href="https://independent.academia.edu/MichaelRieder">Michael Rieder</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Therapeutic Drug Monitoring, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The Detection of Cortisol in Human Sweat","attachmentId":115542483,"attachmentType":"pdf","work_url":"https://www.academia.edu/120368623/The_Detection_of_Cortisol_in_Human_Sweat","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/120368623/The_Detection_of_Cortisol_in_Human_Sweat"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="17" data-entity-id="21819372" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/21819372/Cortisol_and_cortisone_ratio_in_urine_LC_MS_MS_method_validation_and_preliminary_clinical_application">Cortisol and cortisone ratio in urine: LC-MS/MS method validation and preliminary clinical application</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="43043796" href="https://independent.academia.edu/AntonelliGiorgia">Giorgia Antonelli</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="43094241" href="https://independent.academia.edu/CarloArtusi">Carlo Artusi</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="43094692" href="https://unipd.academia.edu/RosalbaGatti">Rosalba Gatti</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Chemistry and Laboratory Medicine, 2000</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cortisol and cortisone ratio in urine: LC-MS/MS method validation and preliminary clinical application","attachmentId":42574522,"attachmentType":"pdf","work_url":"https://www.academia.edu/21819372/Cortisol_and_cortisone_ratio_in_urine_LC_MS_MS_method_validation_and_preliminary_clinical_application","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/21819372/Cortisol_and_cortisone_ratio_in_urine_LC_MS_MS_method_validation_and_preliminary_clinical_application"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="18" data-entity-id="14623609" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/14623609/Quantitation_of_cortisol_and_related_3_oxo_4_ene_steroids_in_urine_using_gas_chromatography_mass_spectrometry_with_stable_isotope_labeled_internal_standards">Quantitation of cortisol and related 3-oxo-4-ene steroids in urine using gas chromatography/mass spectrometry with stable isotope-labeled internal standards</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33570704" href="https://independent.academia.edu/CedricShackleton">Cedric Shackleton</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Steroids, 1996</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Quantitation of cortisol and related 3-oxo-4-ene steroids in urine using gas chromatography/mass spectrometry with stable isotope-labeled internal standards","attachmentId":44023019,"attachmentType":"pdf","work_url":"https://www.academia.edu/14623609/Quantitation_of_cortisol_and_related_3_oxo_4_ene_steroids_in_urine_using_gas_chromatography_mass_spectrometry_with_stable_isotope_labeled_internal_standards","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/14623609/Quantitation_of_cortisol_and_related_3_oxo_4_ene_steroids_in_urine_using_gas_chromatography_mass_spectrometry_with_stable_isotope_labeled_internal_standards"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="19" data-entity-id="120397458" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/120397458/Radioimmunoassay_of_cortisone_in_serum_urine_and_saliva_to_assess_the_status_of_the_cortisol_cortisone_shuttle">Radioimmunoassay of cortisone in serum, urine, and saliva to assess the status of the cortisol–cortisone shuttle</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="221716607" href="https://independent.academia.edu/JimGosling">James P A T R I C K Gosling</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Chemistry, 1997</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Radioimmunoassay of cortisone in serum, urine, and saliva to assess the status of the cortisol–cortisone shuttle","attachmentId":115559991,"attachmentType":"pdf","work_url":"https://www.academia.edu/120397458/Radioimmunoassay_of_cortisone_in_serum_urine_and_saliva_to_assess_the_status_of_the_cortisol_cortisone_shuttle","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/120397458/Radioimmunoassay_of_cortisone_in_serum_urine_and_saliva_to_assess_the_status_of_the_cortisol_cortisone_shuttle"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="20" data-entity-id="74902052" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/74902052/Concerns_regarding_hair_cortisol_as_a_biomarker_of_chronic_stress_in_exercise_and_sport_science">Concerns regarding hair cortisol as a biomarker of chronic stress in exercise and sport science</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58437570" href="https://independent.academia.edu/MarkusGerber1">Markus Gerber</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of sports science & medicine, 2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Concerns regarding hair cortisol as a biomarker of chronic stress in exercise and sport science","attachmentId":82888152,"attachmentType":"pdf","work_url":"https://www.academia.edu/74902052/Concerns_regarding_hair_cortisol_as_a_biomarker_of_chronic_stress_in_exercise_and_sport_science","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/74902052/Concerns_regarding_hair_cortisol_as_a_biomarker_of_chronic_stress_in_exercise_and_sport_science"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related topics</h2><div class="ds-research-interests--pills-container"><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="5769" href="https://www.academia.edu/Documents/in/Mass_Spectrometry">Mass Spectrometry</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="14034" href="https://www.academia.edu/Documents/in/Clinical_Biochemistry">Clinical Biochemistry</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="58431" href="https://www.academia.edu/Documents/in/Cortisol">Cortisol</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="64933" href="https://www.academia.edu/Documents/in/Child">Child</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="83996" href="https://www.academia.edu/Documents/in/Hair">Hair</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="98925" href="https://www.academia.edu/Documents/in/Female">Female</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="111545" href="https://www.academia.edu/Documents/in/Male">Male</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="289271" href="https://www.academia.edu/Documents/in/Aged">Aged</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="295155" href="https://www.academia.edu/Documents/in/Middle_Aged">Middle Aged</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="382075" href="https://www.academia.edu/Documents/in/Adult">Adult</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="398287" href="https://www.academia.edu/Documents/in/Liquid_Chromatography">Liquid Chromatography</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="413192" href="https://www.academia.edu/Documents/in/Sex_Factors">Sex Factors</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="413195" href="https://www.academia.edu/Documents/in/Time_Factors">Time Factors</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="459820" href="https://www.academia.edu/Documents/in/Ether">Ether</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="529560" href="https://www.academia.edu/Documents/in/Gas_Chromatography_mass_Spectrometry">Gas Chromatography/mass Spectrom...</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="546419" href="https://www.academia.edu/Documents/in/Age_Factors">Age Factors</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="1250590" href="https://www.academia.edu/Documents/in/Cortisone">Cortisone</a><a class="js-related-research-interest ds-research-interests--pill" data-entity-id="1293308" href="https://www.academia.edu/Documents/in/Glucocorticoids">Glucocorticoids</a></div></div></div></div></div><div class="footer--content"><ul class="footer--main-links hide-on-mobile"><li><a href="https://www.academia.edu/about">About</a></li><li><a href="https://www.academia.edu/press">Press</a></li><li><a rel="nofollow" href="https://medium.com/academia">Blog</a></li><li><a href="https://www.academia.edu/documents">Papers</a></li><li><a href="https://www.academia.edu/topics">Topics</a></li><li><a href="https://www.academia.edu/hiring"><svg style="width: 13px; height: 13px; position: relative; bottom: -1px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="briefcase" class="svg-inline--fa fa-briefcase fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M320 336c0 8.84-7.16 16-16 16h-96c-8.84 0-16-7.16-16-16v-48H0v144c0 25.6 22.4 48 48 48h416c25.6 0 48-22.4 48-48V288H320v48zm144-208h-80V80c0-25.6-22.4-48-48-48H176c-25.6 0-48 22.4-48 48v48H48c-25.6 0-48 22.4-48 48v80h512v-80c0-25.6-22.4-48-48-48zm-144 0H192V96h128v32z"></path></svg> <strong>We're Hiring!</strong></a></li><li><a href="https://support.academia.edu/"><svg style="width: 12px; height: 12px; position: relative; bottom: -1px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="question-circle" class="svg-inline--fa fa-question-circle fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M504 256c0 136.997-111.043 248-248 248S8 392.997 8 256C8 119.083 119.043 8 256 8s248 111.083 248 248zM262.655 90c-54.497 0-89.255 22.957-116.549 63.758-3.536 5.286-2.353 12.415 2.715 16.258l34.699 26.31c5.205 3.947 12.621 3.008 16.665-2.122 17.864-22.658 30.113-35.797 57.303-35.797 20.429 0 45.698 13.148 45.698 32.958 0 14.976-12.363 22.667-32.534 33.976C247.128 238.528 216 254.941 216 296v4c0 6.627 5.373 12 12 12h56c6.627 0 12-5.373 12-12v-1.333c0-28.462 83.186-29.647 83.186-106.667 0-58.002-60.165-102-116.531-102zM256 338c-25.365 0-46 20.635-46 46 0 25.364 20.635 46 46 46s46-20.636 46-46c0-25.365-20.635-46-46-46z"></path></svg> <strong>Help Center</strong></a></li></ul><ul class="footer--research-interests"><li>Find new research papers in:</li><li><a href="https://www.academia.edu/Documents/in/Physics">Physics</a></li><li><a href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a></li><li><a href="https://www.academia.edu/Documents/in/Biology">Biology</a></li><li><a href="https://www.academia.edu/Documents/in/Health_Sciences">Health Sciences</a></li><li><a href="https://www.academia.edu/Documents/in/Ecology">Ecology</a></li><li><a href="https://www.academia.edu/Documents/in/Earth_Sciences">Earth Sciences</a></li><li><a href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a></li><li><a href="https://www.academia.edu/Documents/in/Mathematics">Mathematics</a></li><li><a href="https://www.academia.edu/Documents/in/Computer_Science">Computer Science</a></li></ul><ul class="footer--legal-links hide-on-mobile"><li><a href="https://www.academia.edu/terms">Terms</a></li><li><a href="https://www.academia.edu/privacy">Privacy</a></li><li><a href="https://www.academia.edu/copyright">Copyright</a></li><li>Academia ©2024</li></ul></div> </body> </html>