Nestin Antibody (196908) [Unconjugated] (MAB1259): Novus Biologicals

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View Mouse Monoclonal anti-Nestin Antibody (196908) [Unconjugated] (MAB1259). Validated Applications: CyTOF-ready, Flow, ICC/IF. Validated Species: Human. Sample size available. Range of directly conjugated antibodies available." /> <meta property="og:description" content="Cited in 161 publications. View Mouse Monoclonal anti-Nestin Antibody (196908) [Unconjugated] (MAB1259). Validated Applications: CyTOF-ready, Flow, ICC/IF. Validated Species: Human. Sample size available. Range of directly conjugated antibodies available." /> <meta property="og:image" content="//images.novusbio.com/thumbnails2/Nestin_MAB1259_Immunocytochemistry_6561.jpg" /> <meta name="robots" content="index,follow" /> <meta name="baidu-site-verification" content="xQr2vSIwwB" /> <script id="json-ld" type="application/ld+json">[{"@context":"http://schema.org","@type":"Product","description":"Mouse Monoclonal Anti-Nestin Antibody (196908) [Unconjugated]. 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View our protocol for Fluorescent ICC Staining of Cells on Coverslips.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/antibody/mab1259_human-nestin-mab-clone-196908-intracellular-staining-by-flow-cytometry-24120239959.jpg","caption":"A172 cells were stained with Mouse Anti-Human Nestin Monoclonal Antibody (Catalog # MAB1259, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & Permeabilization Buffer Kit (Catalog # FC012). 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Western analysis of A53T cells shows elevated soluble alpha -syn at the mitochondria relative to corrected cells at DIV 14 and DIV 60 (denoted by ** and * respectively). Quantification of soluble and insoluble alpha -syn levels in mitochondrial fractions normalized to Coomassie (c). Data represent mean\u2009\u00b1\u2009s.e.m. *P\u2009<\u20090.05, **P\u2009<\u20090.01 by ANOVA followed by Tukey\u2019s post hoc test, n\u2009=\u20094. d, e Micrographs of corrected and A53T-mutant NPCs expressing the negative charge probe RPRE-RFP and CL-GFP show RPRE-RFP translocation from a primarily plasma membrane localization in isogenic-corrected hNs to a punctate intracellular localization in A53T hNs in tight cellular localization with CL-GFP (d). Quantification of percent total cell number with colocalized RPRE-RFP and CL-GFP (e). Data represent mean\u2009\u00b1\u2009s.e.m. **P\u2009<\u20090.0001 by t-test, n\u2009=\u20093 coverslips over 2 independent differentiations, DIV: 14; scale bar: 10\u2009\u03bcm. f, g Fluorescence resonance energy transfer (FRET) from CL-GFP to RPRE-RFP in hiPSC-derived A53T and corrected hNs or hESC-derived WT, A53T and E46K hNs was assessed (f) and mean FRET intensity was quantified (g). Data represent mean\u2009\u00b1\u2009s.e.m. **P\u2009<\u20090.01 by ANOVA followed by Tukey\u2019s post hoc test, for hiPSCs, n\u2009=\u20096, for hESCs, n\u2009=\u20098 coverslips over two independent differentiations, DIV: 14. Scale bar: 10\u2009\u00b5m. h Mitochondria were isolated from the SNpc of 6-month-old WT and A53T transgenic animals and labeled with Annexin V to measure the abundance of cardiolipin on the mitochondrial surface. Controls were rotenone-exposed WT samples. Animals were not randomized, nor was the analysis blinded. Data represent mean\u2009\u00b1\u2009s.e.m. **P\u2009<\u20090.01 by ANOVA followed by Dunnett post hoc test, n\u2009=\u20094. Clipart was obtained at clker.com Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-018-03241-9), licensed under a CC-BY license. Not internally tested by R&D Systems.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410484375.jpg","caption":"MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410482422.jpg","caption":"MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410481178.jpg","caption":"Neural stem cells could proliferate and differentiate into neurons and astrocytes.(A) Representative photomicrograph of neurospheres in culture. (B) Immunocytochemical staining of purified NSCs with Nestin. (C) Immunocytochemical staining of purified protoplasmic astrocytes with GFAP. (D) Immunocytochemical staining of purified neurons with beta -tubulin-III. (E) Nucleus staining of differentiated cells from NSCs with DAPI. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-4120241048544.jpg","caption":"miR\u2013381 promoted neural stem cells proliferation.(A) The expression of miR\u2013381 was measured by qRT-PCR. (B) CCK\u20138 was performed to detect the neural stem cells proliferation. (C) The mRNA expression of nestin was detected by qRT-PCR. (D) The protein expression of nestin was measured by Western blot. **p<0.01 and ***p<0.001. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410485448.jpg","caption":"Dissimilar tumorigenesis in the in vivo animal model.(a) Kaplan-Meier survival plots; 3 mice were used for cells of each clone. (b) Representative brain tumors of NOD-SCID mice harboring xenografts of the clones #2 (upper left), #3 (lower left), #4 (upper right) and #5 (lower right); H.E. staining, arrows: tumor, scale bar = 5\u2005mm. (c) A representative xenograft of the clone #4; nestin-positive cells infiltrated the contralateral hemisphere (arrows). Scale bars = 5\u2005mm (left), 1\u2005mm (middle), 50\u2005\u03bcm (right). Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/25623281), licensed under a CC-BY license. Not internally tested by R&D Systems.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-2282024173319.jpg","caption":"Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and DIV 60 labeled for total alpha -syn, PS129, TH (DA neuronal marker), nestin (NPC marker) or GAPDH show that levels of PS129-modified alpha -syn are elevated in A53T hNs at DIV 14 and remain elevated at DIV 60 relative to corrected cells. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/29483518), licensed under a CC-BY license. 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5.1724696046-473375462.1712005244" style="margin: 0 10px;" target="_blank"><img alt="Novus Biologicals products are now on bio-techne.com" src="https://images.novusbio.com/design/ready-to-buy-novus-products-login.png" style="height:120px; width:940px" /></a></div> </div> </div> </div> <h1>Nestin Antibody (196908) [Unconjugated]</h1> </div> <div class="clear"></div> <div> <div class="region region-content"> <div id="block-et-messages-et-messages-block" class="block block-et-messages"> <div class="content"> <span></span> </div> </div> <div id="block-system-main" class="block block-system"> <div class="content"> <div class="grid_16"><div class="ds_info float_left"><a href="#PublicationSection"><div class="sprite_pubBook_large"></div></a> <a href="#PublicationSection" class="bottom2"><span class="ctr">(161 Publications)</span></a></div><div class="ds_info float_left"><a href="#ReviewsSection"><div class="dsSprite_stars4"></div></a> <a href="#ReviewsSection" class="bottom0"><span class="ctr">(3 Reviews)</span></a></div><div class="ds_info float_left"> <a href="/common-name/nestin"><div class="sprite_allRelated"></div></a> <a href="/common-name/nestin" class="bottom4"><span class="ctr">See All Related</span></a> </div><div class="ds_info float_left"><a href="/reviews/MAB1259"><div class="dsSprite_submitreview"></div></a> <a href="/reviews/MAB1259" class="bottom4"><span class="ctr">Submit a Review</span></a></div></div></div><div class="modalWrapper" style="display:none;"> <h2>Species Glossary</h2> <hr class="customhr"/> <img src="//images.novusbio.com/design/bunny.gif" alt="Species Glossary Rabbit" style="float: right;"> <table class="modalTable"> <tr> <td>At</td> <td>=</td> <td>A. thaliana</td> <td>SyHa</td> <td>=</td> <td>Golden Syrian Hamster</td> </tr> <tr> <td>All</td> <td>=</td> <td>All Species</td> <td>Ha</td> <td>=</td> <td>Hamster</td> </tr> <tr> <td>An</td> <td>=</td> <td>Animal</td> <td>Hu</td> <td>=</td> <td>Human</td> </tr> <tr> <td>ArHa</td> <td>=</td> <td>Armenian Hamster</td> <td>I</td> <td>=</td> <td>Insect</td> </tr> <tr> <td>Av</td> <td>=</td> <td>Avian</td> <td>Ll</td> <td>=</td> <td>Llama</td> </tr> <tr> <td>Bb</td> <td>=</td> <td>Baboon</td> <td>Ma</td> <td>=</td> <td>Mammal</td> </tr> <tr> <td>Ba</td> <td>=</td> <td>Bacteria</td> <td>Mk</td> <td>=</td> <td>Monkey</td> </tr> <tr> <td>Bv</td> <td>=</td> <td>Bovine</td> <td>Mu</td> <td>=</td> <td>Mouse</td> </tr> <tr> <td>Ca</td> <td>=</td> <td>Canine</td> <td>Multi</td> <td>=</td> <td>Multi-species</td> </tr> <tr> <td>Ce</td> <td>=</td> <td>C. Elegans</td> <td>NA</td> <td>=</td> <td>Non-species specific</td> </tr> <tr> <td>Ch</td> <td>=</td> <td>Chicken</td> <td>Or</td> <td>=</td> <td>Orangutan</td> </tr> <tr> <td>ChHa</td> <td>=</td> <td>Chinese Hamster</td> <td>Pl</td> <td>=</td> <td>Plant</td> </tr> <tr> <td>Cm</td> <td>=</td> <td>Cynomolgus Monkey</td> <td>Pm</td> <td>=</td> <td>Primate</td> </tr> <tr> <td>Do</td> <td>=</td> <td>Donkey</td> <td>Po</td> <td>=</td> <td>Porcine</td> </tr> <tr> <td>Dr</td> <td>=</td> <td>Drosophilia</td> <td>Rb</td> <td>=</td> <td>Rabbit</td> </tr> <tr> <td>Ec</td> <td>=</td> <td>E. Coli</td> <td>Rt</td> <td>=</td> <td>Rat</td> </tr> <tr> <td>Eq</td> <td>=</td> <td>Equine</td> <td>RM</td> <td>=</td> <td>Rhesus Macaque</td> </tr> <tr> <td>Fe</td> <td>=</td> <td>Feline</td> <td>Sh</td> <td>=</td> <td>Sheep</td> </tr> <tr> <td>Ft</td> <td>=</td> <td>Ferret</td> <td>Vb</td> <td>=</td> <td>Vertebrate</td> </tr> <tr> <td>Fi</td> <td>=</td> <td>Fish</td> <td>Vi</td> <td>=</td> <td>Virus</td> </tr> <tr> <td>Fu</td> <td>=</td> <td>Fungi</td> <td>Xp</td> <td>=</td> <td>Xenopus</td> </tr> <tr> <td>Ge</td> <td>=</td> <td>Gerbil</td> <td>Ye</td> <td>=</td> <td>Yeast</td> </tr> <tr> <td>GP</td> <td>=</td> <td>Guinea Pig</td> <td>Ze</td> <td>=</td> <td>Zebrafish</td> </tr> <tr> <td>Gt</td> <td>=</td> <td>Goat</td> </tr> </table> <div style="text-align: center;margin-left:25px;margin-right:25px;"> <p>Note: Mouseover a species abbreviation on the product page to display the fullname.</p> </div> </div> </div><div class="clear"></div><div class="grid_10 pos_relative"><div class="ds_blue_border equaltop"><div class="imagesleft equaltop"><h2 class="blueHead">Images</h2> <div class="midBlue"> </div><div class="images"><div id="ss_prev_top" class="cycle-pager"><div class="pager_left_on"></div></div><div class="cycle-slideshow slideshows" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-top" data-cycle-prev="#ss_prev_top" data-cycle-next="#ss_next_top" data-cycle-caption="#image-caption" data-cycle-caption-template="Image {{slideNum}} of {{slideCount}}" data-cycle-slides=".big_thumb_container" data-cycle-carousel-visible="5" id="images_cycle" > <div class="sub_image_wrapper"><div id="cycle-circle-pager-top" class="cycle-circle-pager"></div><div id="image-caption"></div> <a class="enlargeTop">(<div class="dsSprite_magGlass"></div> Enlarge)</a></div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize2/Nestin_MAB1259_Immunocytochemistry_6561.jpg" class="top_images" rel="gallery" title="Nestin was detected in immersion fixed human fetal neural progenitor cells using 10 µg/mL Human Nestin Monoclonal Antibody (Catalog # MAB1259) for 3 hours at room temperature. Cells were stained (green) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." > <img src="//images.novusbio.com/images2/Nestin_MAB1259_Immunocytochemistry_6561.jpg" class="big_thumb" alt="Nestin was detected in immersion fixed human fetal neural progenitor cells using 10 µg/mL Human Nestin Monoclonal Antibody (Catalog # MAB1259) for 3 hours at room temperature. Cells were stained (green) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." title="Nestin was detected in immersion fixed human fetal neural progenitor cells using 10 µg/mL Human Nestin Monoclonal Antibody (Catalog # MAB1259) for 3 hours at room temperature. Cells were stained (green) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." /> </a> </div> <div class="alt-caption padding_left5" >Nestin was detected in immersion fixed human fetal neural progenitor cells using 10 µg/mL Human Nestin Monoclonal Antibody (Catalog # MAB1259) for 3 hours at room temperature. Cells were stained (green) and<a class="openGallery" href="#" data-picnum="0"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/antibody/mab1259_human-nestin-mab-clone-196908-intracellular-staining-by-flow-cytometry-24120239959.jpg" class="top_images" rel="gallery" title="A172 cells were stained with Mouse Anti-Human Nestin Monoclonal Antibody (Catalog # MAB1259, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & Permeabilization Buffer Kit (Catalog # FC012). View our protocol for Staining Intracellular Molecules." > <img src="//images.novusbio.com/images/antibody/mab1259_human-nestin-mab-clone-196908-intracellular-staining-by-flow-cytometry-24120239959.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="A172 cells were stained with Mouse Anti-Human Nestin Monoclonal Antibody (Catalog # MAB1259, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & Permeabilization Buffer Kit (Catalog # FC012). View our protocol for Staining Intracellular Molecules." title="A172 cells were stained with Mouse Anti-Human Nestin Monoclonal Antibody (Catalog # MAB1259, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & Permeabilization Buffer Kit (Catalog # FC012). View our protocol for Staining Intracellular Molecules." /> </a> </div> <div class="alt-caption padding_left5" >A172 cells were stained with Mouse Anti-Human Nestin Monoclonal Antibody (Catalog # MAB1259, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated<a class="openGallery" href="#" data-picnum="1"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410481129.jpg" class="top_images" rel="gallery" title="Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and DIV 60 labeled for total alpha -syn, PS129, TH (DA neuronal marker), nestin (NPC marker) or GAPDH show that levels of PS129-modified alpha -syn are elevated in A53T hNs at DIV 14 and remain elevated at DIV 60 relative to corrected cells. b, c Mitochondria were purified from A53T cells and genetically corrected cells at both DIV 14 and DIV 60. Lysates were then separated based on TX-100 solubility (soluble) or urea solubility (insoluble). Western analysis of A53T cells shows elevated soluble alpha -syn at the mitochondria relative to corrected cells at DIV 14 and DIV 60 (denoted by ** and * respectively). Quantification of soluble and insoluble alpha -syn levels in mitochondrial fractions normalized to Coomassie (c). Data represent mean ± s.e.m. *P < 0.05, **P < 0.01 by ANOVA followed by Tukey’s post hoc test, n = 4. d, e Micrographs of corrected and A53T-mutant NPCs expressing the negative charge probe RPRE-RFP and CL-GFP show RPRE-RFP translocation from a primarily plasma membrane localization in isogenic-corrected hNs to a punctate intracellular localization in A53T hNs in tight cellular localization with CL-GFP (d). Quantification of percent total cell number with colocalized RPRE-RFP and CL-GFP (e). Data represent mean ± s.e.m. **P < 0.0001 by t-test, n = 3 coverslips over 2 independent differentiations, DIV: 14; scale bar: 10 μm. f, g Fluorescence resonance energy transfer (FRET) from CL-GFP to RPRE-RFP in hiPSC-derived A53T and corrected hNs or hESC-derived WT, A53T and E46K hNs was assessed (f) and mean FRET intensity was quantified (g). Data represent mean ± s.e.m. **P < 0.01 by ANOVA followed by Tukey’s post hoc test, for hiPSCs, n = 6, for hESCs, n = 8 coverslips over two independent differentiations, DIV: 14. Scale bar: 10 µm. h Mitochondria were isolated from the SNpc of 6-month-old WT and A53T transgenic animals and labeled with Annexin V to measure the abundance of cardiolipin on the mitochondrial surface. Controls were rotenone-exposed WT samples. Animals were not randomized, nor was the analysis blinded. Data represent mean ± s.e.m. **P < 0.01 by ANOVA followed by Dunnett post hoc test, n = 4. Clipart was obtained at clker.com Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-018-03241-9), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/mab1259_human-nestin-mab-clone-196908-41202410481129.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and DIV 60 labeled for total alpha -syn, PS129, TH (DA neuronal marker), nestin (NPC marker) or GAPDH show that levels of PS129-modified alpha -syn are elevated in A53T hNs at DIV 14 and remain elevated at DIV 60 relative to corrected cells. b, c Mitochondria were purified from A53T cells and genetically corrected cells at both DIV 14 and DIV 60. Lysates were then separated based on TX-100 solubility (soluble) or urea solubility (insoluble). Western analysis of A53T cells shows elevated soluble alpha -syn at the mitochondria relative to corrected cells at DIV 14 and DIV 60 (denoted by ** and * respectively). Quantification of soluble and insoluble alpha -syn levels in mitochondrial fractions normalized to Coomassie (c). Data represent mean ± s.e.m. *P < 0.05, **P < 0.01 by ANOVA followed by Tukey’s post hoc test, n = 4. d, e Micrographs of corrected and A53T-mutant NPCs expressing the negative charge probe RPRE-RFP and CL-GFP show RPRE-RFP translocation from a primarily plasma membrane localization in isogenic-corrected hNs to a punctate intracellular localization in A53T hNs in tight cellular localization with CL-GFP (d). Quantification of percent total cell number with colocalized RPRE-RFP and CL-GFP (e). Data represent mean ± s.e.m. **P < 0.0001 by t-test, n = 3 coverslips over 2 independent differentiations, DIV: 14; scale bar: 10 μm. f, g Fluorescence resonance energy transfer (FRET) from CL-GFP to RPRE-RFP in hiPSC-derived A53T and corrected hNs or hESC-derived WT, A53T and E46K hNs was assessed (f) and mean FRET intensity was quantified (g). Data represent mean ± s.e.m. **P < 0.01 by ANOVA followed by Tukey’s post hoc test, for hiPSCs, n = 6, for hESCs, n = 8 coverslips over two independent differentiations, DIV: 14. Scale bar: 10 µm. h Mitochondria were isolated from the SNpc of 6-month-old WT and A53T transgenic animals and labeled with Annexin V to measure the abundance of cardiolipin on the mitochondrial surface. Controls were rotenone-exposed WT samples. Animals were not randomized, nor was the analysis blinded. Data represent mean ± s.e.m. **P < 0.01 by ANOVA followed by Dunnett post hoc test, n = 4. Clipart was obtained at clker.com Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-018-03241-9), licensed under a CC-BY license. Not internally tested by R&D Systems." title="Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and DIV 60 labeled for total alpha -syn, PS129, TH (DA neuronal marker), nestin (NPC marker) or GAPDH show that levels of PS129-modified alpha -syn are elevated in A53T hNs at DIV 14 and remain elevated at DIV 60 relative to corrected cells. b, c Mitochondria were purified from A53T cells and genetically corrected cells at both DIV 14 and DIV 60. Lysates were then separated based on TX-100 solubility (soluble) or urea solubility (insoluble). Western analysis of A53T cells shows elevated soluble alpha -syn at the mitochondria relative to corrected cells at DIV 14 and DIV 60 (denoted by ** and * respectively). Quantification of soluble and insoluble alpha -syn levels in mitochondrial fractions normalized to Coomassie (c). Data represent mean ± s.e.m. *P < 0.05, **P < 0.01 by ANOVA followed by Tukey’s post hoc test, n = 4. d, e Micrographs of corrected and A53T-mutant NPCs expressing the negative charge probe RPRE-RFP and CL-GFP show RPRE-RFP translocation from a primarily plasma membrane localization in isogenic-corrected hNs to a punctate intracellular localization in A53T hNs in tight cellular localization with CL-GFP (d). Quantification of percent total cell number with colocalized RPRE-RFP and CL-GFP (e). Data represent mean ± s.e.m. **P < 0.0001 by t-test, n = 3 coverslips over 2 independent differentiations, DIV: 14; scale bar: 10 μm. f, g Fluorescence resonance energy transfer (FRET) from CL-GFP to RPRE-RFP in hiPSC-derived A53T and corrected hNs or hESC-derived WT, A53T and E46K hNs was assessed (f) and mean FRET intensity was quantified (g). Data represent mean ± s.e.m. **P < 0.01 by ANOVA followed by Tukey’s post hoc test, for hiPSCs, n = 6, for hESCs, n = 8 coverslips over two independent differentiations, DIV: 14. Scale bar: 10 µm. h Mitochondria were isolated from the SNpc of 6-month-old WT and A53T transgenic animals and labeled with Annexin V to measure the abundance of cardiolipin on the mitochondrial surface. Controls were rotenone-exposed WT samples. Animals were not randomized, nor was the analysis blinded. Data represent mean ± s.e.m. **P < 0.01 by ANOVA followed by Dunnett post hoc test, n = 4. Clipart was obtained at clker.com Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-018-03241-9), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and<a class="openGallery" href="#" data-picnum="2"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410484375.jpg" class="top_images" rel="gallery" title="MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/mab1259_human-nestin-mab-clone-196908-41202410484375.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems." title="MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived<a class="openGallery" href="#" data-picnum="3"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410482422.jpg" class="top_images" rel="gallery" title="MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/mab1259_human-nestin-mab-clone-196908-41202410482422.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems." title="MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived orthotopic brain tumors from vehicle (CTRL), TMZ or TMZ/metformin (Combo) treated mice were analyzed for Ki67, Nestin and CD133 markers by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. H&E was performed for morphological evaluation of the tumors. Representative images are shown with original magnification x200. (C) Variation of T98G tumor volume measured using caliper after treatment expressed as percentage of volume variation. In T98G xenograft model already at 7 days, the combined treatment significantly slowed down tumor growth compared to control (p value = 0.005), moreover a transient reduction was observed with MET (p value = 0.03). After 3 weeks, only Combo-treated mice displayed tumor smaller than vehicle (p value = 0.04). Error bars indicate SEM. (D) T98G tumors from vehicle (CTRL), TMZ, MET or TMZ/metformin (Combo) treated mice, were analyzed for Ki67, Nestin and CD133 markers expression by immunohistochemistry. No difference between the tumor edge and bulk areas in IHC staining intensities or percentages of positive cells was observed for any of the investigated markers. Hematoxylin and eosin staining (H&E) was performed for morphological evaluation of the tumors. Representative images are shown with Original magnification x200. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/lookup/doi/10.18632/oncotarget.23028), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >MET and TMZ effects in in vivo glioma models(A) Variation of U251 tumor volume measured at contrast-enhanced T1 MRI after treatment expressed as percentage of volume change. Error bars indicate SEM. (B) U251 derived<a class="openGallery" href="#" data-picnum="4"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410481178.jpg" class="top_images" rel="gallery" title="Neural stem cells could proliferate and differentiate into neurons and astrocytes.(A) Representative photomicrograph of neurospheres in culture. (B) Immunocytochemical staining of purified NSCs with Nestin. (C) Immunocytochemical staining of purified protoplasmic astrocytes with GFAP. (D) Immunocytochemical staining of purified neurons with beta -tubulin-III. (E) Nucleus staining of differentiated cells from NSCs with DAPI. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/mab1259_human-nestin-mab-clone-196908-41202410481178.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="Neural stem cells could proliferate and differentiate into neurons and astrocytes.(A) Representative photomicrograph of neurospheres in culture. (B) Immunocytochemical staining of purified NSCs with Nestin. (C) Immunocytochemical staining of purified protoplasmic astrocytes with GFAP. (D) Immunocytochemical staining of purified neurons with beta -tubulin-III. (E) Nucleus staining of differentiated cells from NSCs with DAPI. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems." title="Neural stem cells could proliferate and differentiate into neurons and astrocytes.(A) Representative photomicrograph of neurospheres in culture. (B) Immunocytochemical staining of purified NSCs with Nestin. (C) Immunocytochemical staining of purified protoplasmic astrocytes with GFAP. (D) Immunocytochemical staining of purified neurons with beta -tubulin-III. (E) Nucleus staining of differentiated cells from NSCs with DAPI. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >Neural stem cells could proliferate and differentiate into neurons and astrocytes.(A) Representative photomicrograph of neurospheres in culture. (B) Immunocytochemical staining of purified NSCs with Nestin. (C)<a class="openGallery" href="#" data-picnum="5"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-4120241048544.jpg" class="top_images" rel="gallery" title="miR–381 promoted neural stem cells proliferation.(A) The expression of miR–381 was measured by qRT-PCR. (B) CCK–8 was performed to detect the neural stem cells proliferation. (C) The mRNA expression of nestin was detected by qRT-PCR. (D) The protein expression of nestin was measured by Western blot. **p<0.01 and ***p<0.001. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/mab1259_human-nestin-mab-clone-196908-4120241048544.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="miR–381 promoted neural stem cells proliferation.(A) The expression of miR–381 was measured by qRT-PCR. (B) CCK–8 was performed to detect the neural stem cells proliferation. (C) The mRNA expression of nestin was detected by qRT-PCR. (D) The protein expression of nestin was measured by Western blot. **p<0.01 and ***p<0.001. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems." title="miR–381 promoted neural stem cells proliferation.(A) The expression of miR–381 was measured by qRT-PCR. (B) CCK–8 was performed to detect the neural stem cells proliferation. (C) The mRNA expression of nestin was detected by qRT-PCR. (D) The protein expression of nestin was measured by Western blot. **p<0.01 and ***p<0.001. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/26431046), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >miR–381 promoted neural stem cells proliferation.(A) The expression of miR–381 was measured by qRT-PCR. (B) CCK–8 was performed to detect the neural stem cells proliferation. (C) The mRNA expression of nestin was<a class="openGallery" href="#" data-picnum="6"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-41202410485448.jpg" class="top_images" rel="gallery" title="Dissimilar tumorigenesis in the in vivo animal model.(a) Kaplan-Meier survival plots; 3 mice were used for cells of each clone. (b) Representative brain tumors of NOD-SCID mice harboring xenografts of the clones #2 (upper left), #3 (lower left), #4 (upper right) and #5 (lower right); H.E. staining, arrows: tumor, scale bar = 5 mm. (c) A representative xenograft of the clone #4; nestin-positive cells infiltrated the contralateral hemisphere (arrows). Scale bars = 5 mm (left), 1 mm (middle), 50 μm (right). Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/25623281), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/mab1259_human-nestin-mab-clone-196908-41202410485448.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="Dissimilar tumorigenesis in the in vivo animal model.(a) Kaplan-Meier survival plots; 3 mice were used for cells of each clone. (b) Representative brain tumors of NOD-SCID mice harboring xenografts of the clones #2 (upper left), #3 (lower left), #4 (upper right) and #5 (lower right); H.E. staining, arrows: tumor, scale bar = 5 mm. (c) A representative xenograft of the clone #4; nestin-positive cells infiltrated the contralateral hemisphere (arrows). Scale bars = 5 mm (left), 1 mm (middle), 50 μm (right). Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/25623281), licensed under a CC-BY license. Not internally tested by R&D Systems." title="Dissimilar tumorigenesis in the in vivo animal model.(a) Kaplan-Meier survival plots; 3 mice were used for cells of each clone. (b) Representative brain tumors of NOD-SCID mice harboring xenografts of the clones #2 (upper left), #3 (lower left), #4 (upper right) and #5 (lower right); H.E. staining, arrows: tumor, scale bar = 5 mm. (c) A representative xenograft of the clone #4; nestin-positive cells infiltrated the contralateral hemisphere (arrows). Scale bars = 5 mm (left), 1 mm (middle), 50 μm (right). Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/25623281), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >Dissimilar tumorigenesis in the in vivo animal model.(a) Kaplan-Meier survival plots; 3 mice were used for cells of each clone. (b) Representative brain tumors of NOD-SCID mice harboring xenografts of the clones #2<a class="openGallery" href="#" data-picnum="7"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/mab1259_human-nestin-mab-clone-196908-2282024173319.jpg" class="top_images" rel="gallery" title="Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and DIV 60 labeled for total alpha -syn, PS129, TH (DA neuronal marker), nestin (NPC marker) or GAPDH show that levels of PS129-modified alpha -syn are elevated in A53T hNs at DIV 14 and remain elevated at DIV 60 relative to corrected cells. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/29483518), licensed under a CC-BY license. Not internally tested by R&D Systems." > <img src="//images.novusbio.com/images/mab1259_human-nestin-mab-clone-196908-2282024173319.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and DIV 60 labeled for total alpha -syn, PS129, TH (DA neuronal marker), nestin (NPC marker) or GAPDH show that levels of PS129-modified alpha -syn are elevated in A53T hNs at DIV 14 and remain elevated at DIV 60 relative to corrected cells. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/29483518), licensed under a CC-BY license. Not internally tested by R&D Systems." title="Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and DIV 60 labeled for total alpha -syn, PS129, TH (DA neuronal marker), nestin (NPC marker) or GAPDH show that levels of PS129-modified alpha -syn are elevated in A53T hNs at DIV 14 and remain elevated at DIV 60 relative to corrected cells. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/29483518), licensed under a CC-BY license. Not internally tested by R&D Systems." /> </a> </div> <div class="alt-caption padding_left5" >Cardiolipin is externalized to the mitochondrial surface in alpha -syn mutant hNs and transgenic mice in response to alpha -syn accumulation. a Western analysis of lysates from corrected and A53T cells at DIV 14 and<a class="openGallery" href="#" data-picnum="8"> ...read more</a></div> </div></div><div id="ss_next_top" class="cycle-pager"><div class="pager_right_on"></div></div></div></div><div class="productsright pos_relative equaltop"><h2 class="blueHead">Product Details</h2> <div class="midBlue">Summary</div><table class="ds_list"><tr class="lined"> <td><strong>Reactivity</strong></td> <td><span title='Human'>Hu</span><span class="myModal">Species Glossary</span></td> </tr><tr class="lined"> <td><strong>Applications</strong></td> <td><span title='CyTOF-ready'>CyTOF-ready</span>, <span title='Flow Cytometry'>Flow</span>, <span title='Immunocytochemistry/ Immunofluorescence'>ICC/IF</span></td> </tr><tr class="lined"> <td><strong>Clone</strong></td> <td><div>196908</div></td> </tr><tr class="lined"> <td><strong>Clonality</strong></td> <td><div>Monoclonal</div></td> </tr><tr class="lined"> <td><strong>Host</strong></td> <td><div>Mouse</div></td> </tr><tr class="lined"> <td><strong>Conjugate</strong></td> <td><div>Unconjugated</div></td> </tr></table></div> </div></div><div class="grid_6"><div></div> <div class="ds_blue_border equaltop"> <h2 class="blueHead_nopadding">Order Details</h2><ul class="ds_details"><li class="add-to-cart" data-type="full" data-prodname="Human Nestin MAb (Clone 196908)" data-catnum="MAB1259" data-catnums="MAB1259,MAB1259-SP" data-disabled=''><noscript><form autocomplete="off" action="/products/nestin-antibody-196908_mab1259" method="post" id="et-add-multiple-to-cart-form" accept-charset="UTF-8"><div><table class="sticky-enabled"> <thead><tr><th>Size / Catalog#</th><th>Qty</th><th>Price</th> </tr></thead> <tbody> <tr class="odd"><td><div data-msg='' class="atc_catnum">MAB1259-SP</div><div class="atc_size" title="catalog # MAB1259-SP">25 ug</div></td><td><div class="form-item form-type-textfield form-item-rows-MAB1259-SP-quantity"> <input type="text" id="edit-rows-mab1259-sp-quantity" name="rows[MAB1259-SP][quantity]" value="" size="60" maxlength="2" class="form-text" /> </div> </td><td><div class="price"> $179.00</div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">5-7 Business Days</td> </tr> <tr class="odd"><td><div data-msg='' class="atc_catnum">MAB1259</div><div class="atc_size" title="catalog # MAB1259">100 ug</div></td><td><div class="form-item form-type-textfield form-item-rows-MAB1259-quantity"> <input type="text" id="edit-rows-mab1259-quantity" name="rows[MAB1259][quantity]" value="" size="60" maxlength="2" class="form-text" /> </div> </td><td><div class="price"> $489.00</div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">1-3 Business Days</td> </tr> </tbody> </table> <input class="bulk_custom iframeBulkQuote form-submit" onClick="window.location.assign("https://www.novusbio.com/novus_quoterequest?mlt=Human+Nestin+Antibody&catnum=MAB1259"); return false;" type="submit" id="edit-bulk-request" name="op" value="Bulk Request" /><input class="add_to_cart form-submit" type="submit" id="edit-add-multiple-to-cart" name="op" value="Add To Cart " /><input type="hidden" name="form_build_id" value="form-UItgjuHR0xRSe0lImoxhYIUoRcMTGATwh5nkHCE6TwI" /> <input type="hidden" name="form_id" value="et_add_multiple_to_cart_form" /> </div></form></noscript></li></ul><div id="shipping" class="hidden"></td></tr></div><div class="conj_form_buttons"><div class="list_expand options_closed" data-name="Conjugates" data-wrapper-type=".conjugates_wrapper"><div class="options_text">View Available Conjugates</div> <div class="expander option_closed"></div></div><div class="conjugates_wrapper" data-title="Nestin Antibody (196908) [Unconjugated]" data-catnum="MAB1259"><table class="scf_table"> <thead> <tr> <th>Catalog# & Conjugate</th> <th>Size</th> <th class="col_price">Price</th> <th class="col_cart hidden"></th> </tr> </thead> <tbody><tr class="popup_sku" data-sku="IC1259U-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259u" class="conj_link">Alexa Fluor 350</a><br /> <a href="/products/nestin-antibody-196908_ic1259u" class="cat_link">IC1259U-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/585356"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259V-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259v" class="conj_link">Alexa Fluor 405</a><br /> <a href="/products/nestin-antibody-196908_ic1259v" class="cat_link">IC1259V-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/585347"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259G-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259g" class="conj_link">Alexa Fluor 488</a><br /> <a href="/products/nestin-antibody-196908_ic1259g" class="cat_link">IC1259G-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/585381"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259X"> <td> <a href="/products/nestin-antibody-196908_fab1259x" class="conj_link">Alexa Fluor 532</a><br /> <a href="/products/nestin-antibody-196908_fab1259x" class="cat_link">FAB1259X</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983357"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259T-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259t" class="conj_link">Alexa Fluor 594</a><br /> <a href="/products/nestin-antibody-196908_ic1259t" class="cat_link">IC1259T-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/585360"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259R-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259r" class="conj_link">Alexa Fluor 647</a><br /> <a href="/products/nestin-antibody-196908_ic1259r" class="cat_link">IC1259R-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/585372"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259N-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259n" class="conj_link">Alexa Fluor 700</a><br /> <a href="/products/nestin-antibody-196908_ic1259n" class="cat_link">IC1259N-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/585377"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259S-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259s" class="conj_link">Alexa Fluor 750</a><br /> <a href="/products/nestin-antibody-196908_ic1259s" class="cat_link">IC1259S-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/585366"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259A"> <td> <a href="/products/nestin-antibody-196908_ic1259a" class="conj_link">Allophycocyanin</a><br /> <a href="/products/nestin-antibody-196908_ic1259a" class="cat_link">IC1259A</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/420937"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259B"> <td> <a href="/products/nestin-antibody-196908_fab1259b" class="conj_link">Biotin</a><br /> <a href="/products/nestin-antibody-196908_fab1259b" class="cat_link">FAB1259B</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983344"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259CL1"> <td> <a href="/products/nestin-antibody-196908_fab1259cl1" class="conj_link">CoraFluor 1</a><br /> <a href="/products/nestin-antibody-196908_fab1259cl1" class="cat_link">FAB1259CL1</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1312320"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259D"> <td> <a href="/products/nestin-antibody-196908_fab1259d" class="conj_link">DyLight 350</a><br /> <a href="/products/nestin-antibody-196908_fab1259d" class="cat_link">FAB1259D</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983345"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259E"> <td> <a href="/products/nestin-antibody-196908_fab1259e" class="conj_link">DyLight 405</a><br /> <a href="/products/nestin-antibody-196908_fab1259e" class="cat_link">FAB1259E</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983346"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259K"> <td> <a href="/products/nestin-antibody-196908_fab1259k" class="conj_link">DyLight 488</a><br /> <a href="/products/nestin-antibody-196908_fab1259k" class="cat_link">FAB1259K</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983348"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259L"> <td> <a href="/products/nestin-antibody-196908_fab1259l" class="conj_link">DyLight 550</a><br /> <a href="/products/nestin-antibody-196908_fab1259l" class="cat_link">FAB1259L</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983349"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259M"> <td> <a href="/products/nestin-antibody-196908_fab1259m" class="conj_link">DyLight 594</a><br /> <a href="/products/nestin-antibody-196908_fab1259m" class="cat_link">FAB1259M</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983350"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259W"> <td> <a href="/products/nestin-antibody-196908_fab1259w" class="conj_link">DyLight 650</a><br /> <a href="/products/nestin-antibody-196908_fab1259w" class="cat_link">FAB1259W</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983351"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259Y"> <td> <a href="/products/nestin-antibody-196908_fab1259y" class="conj_link">DyLight 680</a><br /> <a href="/products/nestin-antibody-196908_fab1259y" class="cat_link">FAB1259Y</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983352"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259Z"> <td> <a href="/products/nestin-antibody-196908_fab1259z" class="conj_link">DyLight 755</a><br /> <a href="/products/nestin-antibody-196908_fab1259z" class="cat_link">FAB1259Z</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983353"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259F"> <td> <a href="/products/nestin-antibody-196908_ic1259f" class="conj_link">Fluorescein</a><br /> <a href="/products/nestin-antibody-196908_ic1259f" class="cat_link">IC1259F</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/421533"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259H"> <td> <a href="/products/nestin-antibody-196908_fab1259h" class="conj_link">HRP</a><br /> <a href="/products/nestin-antibody-196908_fab1259h" class="cat_link">FAB1259H</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1212416"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF525"> <td> <a href="/products/nestin-antibody-196908_fab1259jf525" class="conj_link">Janelia Fluor 525</a><br /> <a href="/products/nestin-antibody-196908_fab1259jf525" class="cat_link">FAB1259JF525</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1385904"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259I"> <td> <a href="/products/nestin-antibody-196908_fab1259i" class="conj_link">Janelia Fluor 549</a><br /> <a href="/products/nestin-antibody-196908_fab1259i" class="cat_link">FAB1259I</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983355"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF585"> <td> <a href="/products/nestin-antibody-196908_fab1259jf585" class="conj_link">Janelia Fluor 585</a><br /> <a href="/products/nestin-antibody-196908_fab1259jf585" class="cat_link">FAB1259JF585</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1385905"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF635"> <td> <a href="/products/nestin-antibody-196908_fab1259jf635" class="conj_link">Janelia Fluor 635</a><br /> <a href="/products/nestin-antibody-196908_fab1259jf635" class="cat_link">FAB1259JF635</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1385906"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259J"> <td> <a href="/products/nestin-antibody-196908_fab1259j" class="conj_link">Janelia Fluor 646</a><br /> <a href="/products/nestin-antibody-196908_fab1259j" class="cat_link">FAB1259J</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983356"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF669"> <td> <a href="/products/nestin-antibody-196908_fab1259jf669" class="conj_link">Janelia Fluor 669</a><br /> <a href="/products/nestin-antibody-196908_fab1259jf669" class="cat_link">FAB1259JF669</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1385907"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259C"> <td> <a href="/products/nestin-antibody-196908_fab1259c" class="conj_link">PerCP</a><br /> <a href="/products/nestin-antibody-196908_fab1259c" class="cat_link">FAB1259C</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/983354"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259P"> <td> <a href="/products/nestin-antibody-196908_ic1259p" class="conj_link">Phycoerythrin</a><br /> <a href="/products/nestin-antibody-196908_ic1259p" class="cat_link">IC1259P</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/421504"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259MFV450"> <td> <a href="/products/nestin-antibody-196908_fab1259mfv450" class="conj_link">mFluor Violet 450 SE</a><br /> <a href="/products/nestin-antibody-196908_fab1259mfv450" class="cat_link">FAB1259MFV450</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1212417"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259MFV500"> <td> <a href="/products/nestin-antibody-196908_fab1259mfv500" class="conj_link">mFluor Violet 500 SE</a><br /> <a href="/products/nestin-antibody-196908_fab1259mfv500" class="cat_link">FAB1259MFV500</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1212418"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259MFV610"> <td> <a href="/products/nestin-antibody-196908_fab1259mfv610" class="conj_link">mFluor Violet 610 SE</a><br /> <a href="/products/nestin-antibody-196908_fab1259mfv610" class="cat_link">FAB1259MFV610</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart hidden"><a href="/commerce/add-to-cart/1212419"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr> <tr class="scf_footer"> <td colspan="4"><div class="expander option_opened"></div></td> </tr> </tbody> </table> <div class="popup_skus" data-skus='["IC1259U-100UG","IC1259V-100UG","IC1259G-100UG","FAB1259X","IC1259T-100UG","IC1259R-100UG","IC1259N-100UG","IC1259S-100UG","IC1259A","FAB1259B","FAB1259CL1","FAB1259D","FAB1259E","FAB1259K","FAB1259L","FAB1259M","FAB1259W","FAB1259Y","FAB1259Z","IC1259F","FAB1259H","FAB1259JF525","FAB1259I","FAB1259JF585","FAB1259JF635","FAB1259J","FAB1259JF669","FAB1259C","IC1259P","FAB1259MFV450","FAB1259MFV500","FAB1259MFV610"]' data-rendered="false"></div></div><div class="list_expand options_closed" data-name="Formulations" data-wrapper-type=".formulations_wrapper"><div class="options_text">View Available Formulations</div> <div class="expander option_closed"></div></div><div class="formulations_wrapper" data-title="Nestin Antibody (196908) [Unconjugated]" data-catnum="MAB1259"><table class="scf_table"> <thead> <tr> <th>Catalog# & Formulation</th> <th>Size</th> <th class="col_price">Price</th> <th class="col_cart"></th> </tr> </thead> <tbody><tr class="popup_sku" data-sku="IC1259A"> <td> <a href="/products/nestin-antibody-196908_ic1259a" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259a" class="cat_link">IC1259A</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/420937"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259P"> <td> <a href="/products/nestin-antibody-196908_ic1259p" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259p" class="cat_link">IC1259P</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/421504"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259F"> <td> <a href="/products/nestin-antibody-196908_ic1259f" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259f" class="cat_link">IC1259F</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/421533"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="MAB1259-SP"> <td> <a href="/products/nestin-antibody-196908_mab1259" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_mab1259" class="cat_link">MAB1259-SP</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/433368"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259V-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259v" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259v" class="cat_link">IC1259V-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/585347"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259U-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259u" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259u" class="cat_link">IC1259U-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/585356"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259T-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259t" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259t" class="cat_link">IC1259T-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/585360"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259S-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259s" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259s" class="cat_link">IC1259S-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/585366"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259R-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259r" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259r" class="cat_link">IC1259R-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/585372"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259N-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259n" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259n" class="cat_link">IC1259N-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/585377"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr><tr class="popup_sku" data-sku="IC1259G-100UG"> <td> <a href="/products/nestin-antibody-196908_ic1259g" class="conj_link">Carrier Free</a><br /> <a href="/products/nestin-antibody-196908_ic1259g" class="cat_link">IC1259G-100UG</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/585381"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr> <tr class="scf_footer"> <td colspan="4"><div class="expander option_opened"></div></td> </tr> </tbody> </table> <div class="popup_skus" data-skus='["IC1259A","IC1259P","IC1259F","MAB1259-SP","IC1259V-100UG","IC1259U-100UG","IC1259T-100UG","IC1259S-100UG","IC1259R-100UG","IC1259N-100UG","IC1259G-100UG"]' data-rendered="false"></div></div></div><div id="shipping_statement"><span id="shipping_rate"></span></div><div class="shipping_obt_transfer"><span>Novus Biologicals is part of Bio-Techne</span><br><br><a href="https://www.bio-techne.com/p/antibodies/human-nestin-antibody-196908_mab1259" rel="follow" class="btn btn-primary">Shop this product on bio-techne.com</a></div><br><div class="learn_more"> <a href="/guarantee"> <div class="sprite_noImage" title="Novus Biologicals, part of Bio-Techne, offers 100% Guarantee"></div> <div class="learn_more_text">Novus Biologicals, part of Bio-Techne, offers 100% Guarantee</div></a> </div><span id="conj_form" class="hidden"><tr><td colspan="4"><table class="scf_table"> <thead> <tr> <th>Conjugate</th> <th>Catalog #</th> <th class="head_avail">Availability</th> <th>Size</th> <th class="col_price">Price</th> </tr> </thead> <tbody><tr class="popup_sku" data-sku="IC1259U-100UG"> <td><a href="/products/nestin-antibody-196908_ic1259u">Alexa Fluor 350</a></td> <td><a href="/products/nestin-antibody-196908_ic1259u">IC1259U-100UG</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="IC1259V-100UG"> <td><a href="/products/nestin-antibody-196908_ic1259v">Alexa Fluor 405</a></td> <td><a href="/products/nestin-antibody-196908_ic1259v">IC1259V-100UG</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="IC1259G-100UG"> <td><a href="/products/nestin-antibody-196908_ic1259g">Alexa Fluor 488</a></td> <td><a href="/products/nestin-antibody-196908_ic1259g">IC1259G-100UG</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259X"> <td><a href="/products/nestin-antibody-196908_fab1259x">Alexa Fluor 532</a></td> <td><a href="/products/nestin-antibody-196908_fab1259x">FAB1259X</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="IC1259T-100UG"> <td><a href="/products/nestin-antibody-196908_ic1259t">Alexa Fluor 594</a></td> <td><a href="/products/nestin-antibody-196908_ic1259t">IC1259T-100UG</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="IC1259R-100UG"> <td><a href="/products/nestin-antibody-196908_ic1259r">Alexa Fluor 647</a></td> <td><a 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href="/products/nestin-antibody-196908_ic1259a">Allophycocyanin</a></td> <td><a href="/products/nestin-antibody-196908_ic1259a">IC1259A</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259B"> <td><a href="/products/nestin-antibody-196908_fab1259b">Biotin</a></td> <td><a href="/products/nestin-antibody-196908_fab1259b">FAB1259B</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259CL1"> <td><a href="/products/nestin-antibody-196908_fab1259cl1">CoraFluor 1</a></td> <td><a href="/products/nestin-antibody-196908_fab1259cl1">FAB1259CL1</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259D"> <td><a href="/products/nestin-antibody-196908_fab1259d">DyLight 350</a></td> <td><a href="/products/nestin-antibody-196908_fab1259d">FAB1259D</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259E"> <td><a href="/products/nestin-antibody-196908_fab1259e">DyLight 405</a></td> <td><a href="/products/nestin-antibody-196908_fab1259e">FAB1259E</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259K"> <td><a href="/products/nestin-antibody-196908_fab1259k">DyLight 488</a></td> <td><a href="/products/nestin-antibody-196908_fab1259k">FAB1259K</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259L"> <td><a href="/products/nestin-antibody-196908_fab1259l">DyLight 550</a></td> <td><a href="/products/nestin-antibody-196908_fab1259l">FAB1259L</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259M"> <td><a href="/products/nestin-antibody-196908_fab1259m">DyLight 594</a></td> <td><a href="/products/nestin-antibody-196908_fab1259m">FAB1259M</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259W"> <td><a href="/products/nestin-antibody-196908_fab1259w">DyLight 650</a></td> <td><a href="/products/nestin-antibody-196908_fab1259w">FAB1259W</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259Y"> <td><a href="/products/nestin-antibody-196908_fab1259y">DyLight 680</a></td> <td><a href="/products/nestin-antibody-196908_fab1259y">FAB1259Y</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259Z"> <td><a href="/products/nestin-antibody-196908_fab1259z">DyLight 755</a></td> <td><a href="/products/nestin-antibody-196908_fab1259z">FAB1259Z</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="IC1259F"> <td><a href="/products/nestin-antibody-196908_ic1259f">Fluorescein</a></td> <td><a href="/products/nestin-antibody-196908_ic1259f">IC1259F</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259H"> <td><a href="/products/nestin-antibody-196908_fab1259h">HRP</a></td> <td><a href="/products/nestin-antibody-196908_fab1259h">FAB1259H</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF525"> <td><a href="/products/nestin-antibody-196908_fab1259jf525">Janelia Fluor 525</a></td> <td><a href="/products/nestin-antibody-196908_fab1259jf525">FAB1259JF525</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259I"> <td><a href="/products/nestin-antibody-196908_fab1259i">Janelia Fluor 549</a></td> <td><a href="/products/nestin-antibody-196908_fab1259i">FAB1259I</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF585"> <td><a href="/products/nestin-antibody-196908_fab1259jf585">Janelia Fluor 585</a></td> <td><a href="/products/nestin-antibody-196908_fab1259jf585">FAB1259JF585</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF635"> <td><a href="/products/nestin-antibody-196908_fab1259jf635">Janelia Fluor 635</a></td> <td><a href="/products/nestin-antibody-196908_fab1259jf635">FAB1259JF635</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259J"> <td><a href="/products/nestin-antibody-196908_fab1259j">Janelia Fluor 646</a></td> <td><a href="/products/nestin-antibody-196908_fab1259j">FAB1259J</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259JF669"> <td><a href="/products/nestin-antibody-196908_fab1259jf669">Janelia Fluor 669</a></td> <td><a href="/products/nestin-antibody-196908_fab1259jf669">FAB1259JF669</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259C"> <td><a href="/products/nestin-antibody-196908_fab1259c">PerCP</a></td> <td><a href="/products/nestin-antibody-196908_fab1259c">FAB1259C</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="IC1259P"> <td><a href="/products/nestin-antibody-196908_ic1259p">Phycoerythrin</a></td> <td><a href="/products/nestin-antibody-196908_ic1259p">IC1259P</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259MFV450"> <td><a href="/products/nestin-antibody-196908_fab1259mfv450">mFluor Violet 450 SE</a></td> <td><a href="/products/nestin-antibody-196908_fab1259mfv450">FAB1259MFV450</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259MFV500"> <td><a href="/products/nestin-antibody-196908_fab1259mfv500">mFluor Violet 500 SE</a></td> <td><a href="/products/nestin-antibody-196908_fab1259mfv500">FAB1259MFV500</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr><tr class="popup_sku" data-sku="FAB1259MFV610"> <td><a href="/products/nestin-antibody-196908_fab1259mfv610">mFluor Violet 610 SE</a></td> <td><a href="/products/nestin-antibody-196908_fab1259mfv610">FAB1259MFV610</a></td> <td><div class="popup_stock"></div></td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> </tr> <tr class="scf_footer"> <td colspan="5"><div class="expander option_opened"></div></td> </tr> </tbody> </table> <div class="popup_skus" data-skus='["IC1259U-100UG","IC1259V-100UG","IC1259G-100UG","FAB1259X","IC1259T-100UG","IC1259R-100UG","IC1259N-100UG","IC1259S-100UG","IC1259A","FAB1259B","FAB1259CL1","FAB1259D","FAB1259E","FAB1259K","FAB1259L","FAB1259M","FAB1259W","FAB1259Y","FAB1259Z","IC1259F","FAB1259H","FAB1259JF525","FAB1259I","FAB1259JF585","FAB1259JF635","FAB1259J","FAB1259JF669","FAB1259C","IC1259P","FAB1259MFV450","FAB1259MFV500","FAB1259MFV610"]' data-rendered="false"></div></td></tr></span> </div> </div><div class="clear"></div><div class="grid_10"><div><div id="ds_tabs" style="display:none;"> <div class="ds_tab_active" id="dsTabs_datasheet" data-anchor_desc="datasheet">Datasheet</div> <div class="ds_tab" id="dsTabs_reviews-publications" data-anchor_desc="reviews-publications">Reviews & Publications</div> <div class="ds_tab" id="dsTabs_protocols-faqs" data-anchor_desc="protocols-faqs">Protocols & FAQs</div> <div class="ds_tab" id="dsTabs_supportresearch" data-anchor_desc="supportresearch">Support & Research</div> </div><div class="ds_tab_content equalbottom" id="content_datasheet" > <a id="datasheet"></a><h2 class=greyHead2>Nestin Antibody (196908) [Unconjugated] Summary</h2> <div class="ds_info"> <a id="tab1details"></a> <table class="ds_list wide" style="table-layout:fixed;"> <tr class="lined"> <td><strong>Immunogen</strong></td> <td><div>NS0 mouse myeloma cell line transfected with human Nestin</div></td> </tr><tr class="lined"> <td><strong>Specificity</strong></td> <td><div>Detects human Nestin.</div></td> </tr><tr class="lined"> <td><strong>Source</strong></td> <td><div>N/A</div></td> </tr><tr class="lined"> <td><strong>Isotype</strong></td> <td><div>IgG1</div></td> </tr><tr class="lined"> <td><strong>Clonality</strong></td> <td><div>Monoclonal</div></td> </tr><tr class="lined"> <td><strong>Host</strong></td> <td><div>Mouse</div></td> </tr><tr class="lined"> <td><strong>Gene</strong></td> <td><div>NES</div></td> </tr><tr class="lined"> <td><strong>Purity Statement</strong></td> <td><div>Protein A or G purified from hybridoma culture supernatant</div></td> </tr><tr class="lined"> <td><strong>Innovator's Reward</strong></td> <td><div>Test in a species/application not listed above to receive a full credit towards a future purchase.<br/><div class='text_right'><a class='ds_submit_blue ds_regularPad' href='/support/innovators-reward.html'>Learn about the Innovator's Reward</a></div></div></td> </tr> </table> </div> <h2 class="greyHead2">Applications/Dilutions</h2> <div class="ds_info"> <a id="tab1appsdiluts"></a> <table class="ds_list wide"> <tr class="lined"> <td><strong>Dilutions</strong></td> <td> <ul class="ds_noDotList"><li>CyTOF-reported </li><li>Immunocytochemistry 8-25 ug/mL</li><li>Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells</li> </ul> </td> </tr><tr class="lined"> <td><strong>Reviewed Applications</strong></td> <td> <table class="wide"> <tr> <td> Read <a href="#ReviewsSection">3 Reviews</a> rated 4.3<div class="dsSprite_stars4"></div> using <br/>MAB1259 in the following applications:<br /><br /> <ul class="information-list"><li> <div class="information-subject"><a href="#ReviewsSection" class="filter_link" data-destination="review" data-type="application" data-filter="Immunocytochemistry">Immunocytochemistry</a></div> <div class="information-data"></div> </li><li> <div class="information-subject"><a href="#ReviewsSection" class="filter_link" data-destination="review" data-type="application" data-filter="Other">Other</a></div> <div class="information-data"></div> </li><li> <div class="information-subject"><a href="#ReviewsSection" class="filter_link" data-destination="review" data-type="application" data-filter="Immunofluorescence">Immunofluorescence</a></div> <div class="information-data"></div> </li> </ul> </td> </tr> </table> </td> </tr><tr class="lined"> <td><strong>Publications</strong></td> <td> <table> <tr> <td>Read <a href="#PublicationSection"> Publications</a> using<br/> MAB1259 in the following applications:<br /><br /> <ul class="information-list"><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Bioassay">Bioassay</a> </div><div class="information-data">1 publication</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Cell Culture">Cell Culture</a> </div><div class="information-data">1 publication</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Flow Cytometry">Flow Cytometry</a> </div><div class="information-data">10 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="ICC">ICC</a> </div><div class="information-data">66 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="IF">IF</a> </div><div class="information-data">2 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="IHC">IHC</a> </div><div class="information-data">16 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="IHC-Fr">IHC-Fr</a> </div><div class="information-data">4 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="IHC-P">IHC-P</a> </div><div class="information-data">8 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Immunocytochemistry">Immunocytochemistry</a> </div><div class="information-data">4 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Immunohistochemistry">Immunohistochemistry</a> </div><div class="information-data">2 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Western Blot">Western Blot</a> </div><div class="information-data">8 publications</div></li></ul></td> </tr> </table> </td> </tr> </table> </div> <h2 class="greyHead2">Packaging, Storage & Formulations</h2><div class="ds_info"><table class="ds_list"><tr class="lined"> <td><strong>Storage</strong></td> <td><div><b>Use a manual defrost freezer and avoid repeated freeze-thaw cycles. </b><UL><LI>12 months from date of receipt, -20 to -70 °C as supplied.</LI><LI>1 month, 2 to 8 °C under sterile conditions after reconstitution.</LI><LI>6 months, -20 to -70 °C under sterile conditions after reconstitution.</LI></UL></div></td> </tr><tr class="lined"> <td><strong>Buffer</strong></td> <td><div>Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.</div></td> </tr><tr class="lined"> <td><strong>Preservative</strong></td> <td><div>No Preservative</div></td> </tr><tr class="lined"> <td><strong>Reconstitution Instructions</strong></td> <td><div>Reconstitute at 0.5 mg/mL in sterile PBS.</div></td> </tr></table></div> <h2 class="greyHead2">Notes</h2><div class="ds_info"> <a id="tab1notes"></a> <div>This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.</div> </div><h2 class="greyHead2">Alternate Names for Nestin Antibody (196908) [Unconjugated]</h2> <div class="ds_info"> <a id="tab1altnames"></a> <div class="information-list"> <ul><li>FLJ21841</li><li>NES</li><li>Nestin</li></ul></div> </div> <h2 class="greyHead2">Background</h2> <div class="ds_info"> <a id="tab1background"></a> <div>Nestin is a class VI intermediate filament protein (1, 2) that is expressed in stem cells of the central nervous system (CNS) (3) but not in mature CNS cells (4). Nestin expression is used extensively as a marker for CNS stem cells in the developing nervous system and <EM>in vitro</EM> cultured cells (5-10). Its transient expression is a critical step in the neural differentiation pathway (2). Nestin is also expressed in non-neural stem cell populations, such as pancreatic islet progenitors (11-13) and hematopoietic progenitors (14).<div class="backref"><OL class=ReferencesList> <LI>Hockfield, S. and R.D. McKay (1985) J. Neurosci. <STRONG>5</STRONG>:3310.</LI> <LI>Lendahl, U. <EM>et al</EM>. (1990) Cell <STRONG>60</STRONG>:585.</LI> <LI>Frederiksen, K. and R.D. McKay (1988) J. Neurosci. <STRONG>8</STRONG>:1144.</LI> <LI>Tohyama, T. <EM>et. al.</EM> (1992) Lab. Invest. <STRONG>66</STRONG>:303.</LI> <LI>Uchida, N. <EM>et al</EM>. (2000) Proc. Natl. Acad.Sci. USA <STRONG>97</STRONG>:14720.</LI> <LI>Frederiksen, K. <EM>et al.</EM> (1988) Neuron <STRONG>1</STRONG>:439.</LI> <LI>Cattaneo, E. <EM>et al.</EM> (1990) Nature <STRONG>347</STRONG>:762.</LI> <LI>Reynolds, B.A. and S. Weiss (1992) Science <STRONG>255</STRONG>:1707.</LI> <LI>Rietze, R.L. <EM>et al.</EM> (2001) Nature <STRONG>412</STRONG>:736.</LI> <LI>Carpenter, M.K. <EM>et al</EM>. (2001) Exp. Neurol <STRONG>172</STRONG>:383.</LI> <LI>Zulewski, H. <EM>et al.</EM> (2001) Diabetes <STRONG>50</STRONG>:521.</LI> <LI>Lumelsky, N. <EM>et al</EM>. (2001) Science <STRONG>292</STRONG>:1389.</LI> <LI>Lechner, A. <EM>et al</EM>. (2002) Biochem.Biophys. Res. Commun. <STRONG>293</STRONG>:670.</LI> <LI>Shih, C.C. <EM>et al.</EM> (2001) Blood <STRONG>98</STRONG>:2412.</LI></OL></div></div> </div> <h2 class="greyHead2">Limitations</h2> <div class="ds_info"> <a id="tab1background"></a> <div>This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are <a href="/support/quality-assurance.html">guaranteed</a> for 1 year from date of receipt.</div> </div><h2 class="greyHead2">Customers Who Viewed This Item Also Viewed...</h2> <a id="custalsoviewed"></a><div id="cav_prev"><div class="sprite_leftArrow"></div></div> <div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout=0 data-cycle-prev="#cav_prev" data-cycle-next="#cav_next" data-cycle-slides="div.ds_cav_group" id="ds_customer_also_viewed"><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB300-141"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/gfap-antibody_nb300-141" style="overflow: hidden; width: 280px;" title="GFAP Antibody">GFAP Antibody</a>    </div><div class="sub-header">NB300-141</div> <div class="images_customers"><div id="ss_prev_cav0" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-0" data-cycle-prev="#ss_prev_cav0" data-cycle-next="#ss_next_cav0" data-cycle-slides="div.big_thumb_cust_container" data-index=0 ><div class="big_thumb_cust_container"> <a href="/products/gfap-antibody_nb300-141" title="Immunohistochemistry: GFAP Antibody [NB300-141] - Analysis of a rat cerebellum section stained with rabbit polyclonal antibody to GFAP, NB300-141, dilution 1:5000 in green and mouse monoclonal antibody to MeCP2, dilution 1:500, in red. The blue is DAPI staining of nuclear DNA. Following transcardial perfusion of rat with 4% paraformaldehyde, brain was post fixed for 1 hour, cut to 45 uM, and free-floating sections were stained with above antibodies. The GFAP antibody stains the network of astrocytic cells and the processes of Bergmann glia in the molecular layer. The MeCP2 antibody specifically labels nuclei of certain neurons." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images/GFAP-Antibody-Immunocytochemistry-Immunofluorescence-NB300-141-img0011.jpg" alt="Immunohistochemistry GFAP Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/gfap-antibody_nb300-141" title="Western Blot: GFAP Antibody [NB300-141] - Analysis of different tissue lysates using rabbit polyclonal antibody to GFAP, NB300-141, dilution 1:5000 in green: [1] protein standard (red), [2] rat brain, [3] rat spinal cord, [4] mouse brain, [5] mouse spinal cord. Strong band at about 50 kDa corresponds to the major isotype of the GFAP protein. Smaller isotypes and proteolytic fragments of GFAP are also detected on the blot." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images/GFAP-Antibody-Western-Blot-NB300-141-img0012.jpg" alt="Western Blot GFAP Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/gfap-antibody_nb300-141" title="Western Blot: GFAP Antibody [NB300-141] - Analysis of Rat brain lysate. Antibody at 1:5000. Specific band running with an apparent SDS-PAGE molecular weight of ~50 kDa corresponds to rodent GFAP was observed." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images/GFAP-Antibody-Western-Blot-NB300-141-img0006.jpg" alt="Western Blot GFAP Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav0" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-0" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/gfap-antibody_nb300-141#ReviewsSection"> <div class="sprite_5Stars"></div> (12 Reviews</a>) </div> <div class="tiny"> <a href="/products/gfap-antibody_nb300-141#PublicationSection"> <div class="sprite_pubBook"></div> (108 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Bv, Ch, Eq, Gp, Hu, Mu, Po, Rb, Rt</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB300-223"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/vimentin-antibody_nb300-223" style="overflow: hidden; width: 280px;" title="Vimentin Antibody">Vimentin Antibody</a>    </div><div class="sub-header">NB300-223</div> <div class="images_customers"><div id="ss_prev_cav1" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-1" data-cycle-prev="#ss_prev_cav1" data-cycle-next="#ss_next_cav1" data-cycle-slides="div.big_thumb_cust_container" data-index=1 ><div class="big_thumb_cust_container"> <a href="/products/vimentin-antibody_nb300-223" title="Immunocytochemistry/Immunofluorescence: Vimentin Antibody [NB300-223] - Analysis of HeLa cell culture. Antibody at 1:10,000 in green, and costained with mouse mAb to actin, dilution 1:500 in red. The blue is DAPI staining of nuclear DNA. The vimentin antibody stains the intermediate filament network while the actin antibody labels the submembranous cytoskeleton, stress fibers, and bundles of actin associated with cell adhesion sites." class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images/Vimentin-Antibody-Immunocytochemistry-Immunofluorescence-NB300-223-img0001.jpg" alt="Immunocytochemistry/ Immunofluorescence Vimentin Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/vimentin-antibody_nb300-223" title="Immunohistochemistry-Frozen: Vimentin Antibody [NB300-223] - 10 um Cryosections from PFA fixed murine brain acute slices stained with Vimentin antibody (1:600) and Alexa Fluor 488 anti chicken IgG. Antibody showed specific staining, also of blood vessels. IHC-Fr image submitted by a verified customer review." class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images/Vimentin-Antibody-Immunohistochemistry-Frozen-NB300-223-img0003.jpg" alt="Immunohistochemistry-Frozen Vimentin Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/vimentin-antibody_nb300-223" title="Immunocytochemistry/Immunofluorescence: Vimentin Antibody [NB300-223] - Human A7 cells. Cells were fixed with 10% formalin and permeabilized with 0.1% TritonX-100. After blocking, cells were incubated with primary antibody (1:600) at 4C O/N followed with Alexa Fluor 488 labeled secondary antibody and counterstained with DAPI and Phalloidin for nuclei and F-actin respectively. Imaged with Leica TCS SP5 confocal microscope. ICC/IF image submitted by a verified customer review." class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images/Vimentin-Antibody-Immunocytochemistry-Immunofluorescence-NB300-223-img0004.jpg" alt="Immunocytochemistry/ Immunofluorescence Vimentin Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav1" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-1" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/vimentin-antibody_nb300-223#ReviewsSection"> <div class="sprite_5Stars"></div> (6 Reviews</a>) </div> <div class="tiny"> <a href="/products/vimentin-antibody_nb300-223#PublicationSection"> <div class="sprite_pubBook"></div> (70 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Bv, Ca, Ch, Eq, Hu, Mu, Po, Rt</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-Fr, IHC-P, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="233-FB"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-fgf-basic-fgf2-bfgf-146-aa-protein_233-fb" style="overflow: hidden; width: 280px;" title="FGF basic/FGF2/bFGF [Unconjugated]">FGF<br> basic/FGF2/bFGF [Unco</a>    </div><div class="sub-header">233-FB</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-2" data-cycle-prev="#ss_prev_cav2" data-cycle-next="#ss_next_cav2" data-cycle-slides="div.big_thumb_cust_container" data-index=2 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-basic-fgf2-bfgf-146-aa-protein_233-fb" title="FGF basic/FGF2/bFGF [Unconjugated]" class="cust_viewed_2"> <img loading="lazy" src="/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png" alt="FGF basic/FGF2/bFGF [Unconjugated]" title="FGF basic/FGF2/bFGF [Unconjugated]" class=" big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-fgf-basic-fgf2-bfgf-146-aa-protein_233-fb#PublicationSection"> <div class="sprite_pubBook"></div> (547 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="236-EG"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-egf-protein-cf_236-eg" style="overflow: hidden; width: 280px;" title="EGF [Unconjugated]">EGF [Unconjugated]</a>    </div><div class="sub-header">236-EG</div> <div class="images_customers"><div id="ss_prev_cav3" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-3" data-cycle-prev="#ss_prev_cav3" data-cycle-next="#ss_next_cav3" data-cycle-slides="div.big_thumb_cust_container" data-index=3 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-egf-protein-cf_236-eg" title="1 µg/lane of Recombinant Human EGF was resolved with SDS-PAGE and visualized by silver staining under reducing (R) conditions, showing a single band at 6 kDa." class="cust_viewed_3" > <img loading="lazy" src="https://images.novusbio.com/images2/EGF_236-EG_234.jpg" alt="SDS-PAGE EGF [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-egf-protein-cf_236-eg" title="Recombinant Human EGF (Catalog # 236‑EG) stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cell line. The ED50 for this effect is 20‑100 pg/mL." class="cust_viewed_3" > <img loading="lazy" src="https://images.novusbio.com/images2/EGF_236EG_1570.jpg" alt="Bioactivity EGF [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-egf-protein-cf_236-eg" title="iPSC-derived human intestinal organoids were cultured using Cultrex&amp;#8482; UltiMatrix RGF Basement Membrane Extract (BME001-05) and intestinal organoid culture medium, which includes Recombinant Human EGF (Catalog # 236-EG), Recombinant Human Noggin (6057-NG), Recombinant Human R-Spondin 1 (4645-RS), and Recombinant Human Wnt-3a (5036-WN), along with the other reagents listed in the intestinal organoid culture medium recipe in the human intestinal organoid culture protocol. (A) Human intestinal organoids were stained using a Rat Anti-Human/Mouse/Rat Vimentin Monoclonal Antibody (MAB2105; green) and a Goat Anti-Human/Mouse Desmin Antigen Affinity-purified Polyclonal Antibody (AF3844; red) to visualize myofibroblast cells and counterstained with DAPI (5748; blue). (B) Human intestinal organoids were stained using a Goat Anti-Human/Mouse E-Cadherin Antigen Affinity-purified Polyclonal Antibody (AF748; green) and a Mouse Anti-Human MUC2 Monoclonal Antibody (Novus Biologicals, Catalog # NBP2-44431; red) and counterstained with DAPI (5748; blue)." class="cust_viewed_3" > <img loading="lazy" src="https://images.novusbio.com/images/236-eg_recombinant-human-egf-protein-cf-bioactivity-25202394053.jpg" alt="Cell Culture EGF [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav3" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-3" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-egf-protein-cf_236-eg#PublicationSection"> <div class="sprite_pubBook"></div> (835 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF3844"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/desmin-antibody_af3844" style="overflow: hidden; width: 280px;" title="Desmin Antibody [Unconjugated]">Desmin Antibody<br> [Unconjugated]</a>    </div><div class="sub-header">AF3844</div> <div class="images_customers"><div id="ss_prev_cav4" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-4" data-cycle-prev="#ss_prev_cav4" data-cycle-next="#ss_next_cav4" data-cycle-slides="div.big_thumb_cust_container" data-index=4 ><div class="big_thumb_cust_container"> <a href="/products/desmin-antibody_af3844" title="Desmin was detected in immersion fixed frozen sections of mouse skeletal muscle using Human Desmin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3844) at 10&amp;nbsp;µg/mL overnight at 4&amp;nbsp;°C. Tissue was stained using the NorthernLights&amp;#8482; 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog&amp;nbsp;# NL001) and counterstained with DAPI (blue). Specific staining was localized to z-lines. View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections." class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images2/Desmin_AF3844_Immunohistochemistry_10689.jpg" alt="Immunohistochemistry Desmin Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/desmin-antibody_af3844" title="Desmin was detected in immersion fixed paraffin-embedded sections of human heart using 15 &amp;micro;g/mL Human Desmin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3844) overnight at 4 &amp;deg;C. Tissue was stained with the Anti-Goat HRP-DAB Cell &amp; Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the sarcoplasm of cardiomyocytes. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images2/Desmin_AF3844_Immunohistochemistry_6808.jpg" alt="Immunohistochemistry Desmin Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/desmin-antibody_af3844" title="Overview of Multi-dimensional Microscopic Molecular Profiling (MMMP).The overall MMMP approach is depicted using an example tissue section from normal human duodenum (sample #1.9.7). (a) Slides were subjected to repeated cycles of staining and imaging with fluorescent primary antibodies and DAPI. At the end of each cycle, fluorescent signal was removed by a chemical bleaching process, and slides were again imaged, before proceeding to the next round of this iterative procedure. After the final antibody stain (#15 Sma), slides were analyzed with a series of histochemical stains. (b) A set of tiling images spanning each tissue section was initially generated by the microscope system. The tiling images were then computationally ‘stitched’ together to produce a single image per staining cycle for each sample. (c) Image registration was performed to align images from the same tissue section across cycles. Mean intensities of the DAPI signal from all immuno-fluorescence images are shown from before (Unregistered) and after (Registered) the image registration procedure was completed. (d) Following registration, signal intensities from the relevant channels for each image (columns) in the MMMP series were extracted for each pixel (rows) within the tissue section and compiled into a large data matrix of in situ molecular profiles. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0128975), licensed under a CC-BY license. Not internally tested by R&amp;D Systems." class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images/af3844_human-mouse-desmin-affinity-purified-polyclonal-ab-41202410331920.jpg" alt="Immunocytochemistry/ Immunofluorescence Desmin Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav4" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-4" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/desmin-antibody_af3844#ReviewsSection"> <div class="sprite_5Stars"></div> (2 Reviews</a>) </div> <div class="tiny"> <a href="/products/desmin-antibody_af3844#PublicationSection"> <div class="sprite_pubBook"></div> (34 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> IHC</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB300-213"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/map2-antibody_nb300-213" style="overflow: hidden; width: 280px;" title="MAP2 Antibody">MAP2 Antibody</a>    </div><div class="sub-header">NB300-213</div> <div class="images_customers"><div id="ss_prev_cav5" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-5" data-cycle-prev="#ss_prev_cav5" data-cycle-next="#ss_next_cav5" data-cycle-slides="div.big_thumb_cust_container" data-index=5 ><div class="big_thumb_cust_container"> <a href="/products/map2-antibody_nb300-213" title="Western blot analysis of whole brain tissue lysates using chicken pAb to microtubule associated protein 2 (MAP2), NB300-213, dilution 1:50,000 in green: [1] protein standard (red), [2] adult rat brain, [3] embryonic E20 rat brain, [4] adult mouse brain. Strong band observed at ~280 kDa mark corresponds to two major isoforms of MAP2 protein referred to as MAP2A and MAP2B. Smaller fragments of these isoforms are also detected if the antibody is used at higher concentrations." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/MAP2-Antibody-Western-Blot-NB300-213-img0005.jpg" alt="Western Blot MAP2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/map2-antibody_nb300-213" title="Human DA neurons 28 DIV stained with MAP2 antibody (blue). ICC/IF image submitted by a verified customer review." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/MAP2-Antibody-Immunocytochemistry-Immunofluorescence-NB300-213-img0002.jpg" alt="Immunocytochemistry/ Immunofluorescence MAP2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/map2-antibody_nb300-213" title="Immunofluorescent analysis of cortical neuron-glial cell culture from E20 rat stained with chicken pAb to microtubule associated protein 2 (MAP2), NB300-213, dilution 1:10,000 in red, and mouse mAb to MAP-tau, NPB2-25162, dilution 1:2,000, in green. The blue is DAPI staining of nuclear DNA. NB300-213 antibody stains dendrites and perikarya of neurons, while NBP2-25162 antibody labels neuronal perikarya, dendrites and also axonal process. As a result perikarya and dendrites appears orange-yellow, since they contain both MAP2 and tau, while axons are green." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/MAP2-Antibody-Immunocytochemistry-Immunofluorescence-NB300-213-img0006.jpg" alt="Immunocytochemistry/ Immunofluorescence MAP2 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav5" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-5" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/map2-antibody_nb300-213#ReviewsSection"> <div class="sprite_5Stars"></div> (5 Reviews</a>) </div> <div class="tiny"> <a href="/products/map2-antibody_nb300-213#PublicationSection"> <div class="sprite_pubBook"></div> (115 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Fe, Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-Fr, IHC-P, KD, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF1759"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/oct-3-4-antibody_af1759" style="overflow: hidden; width: 280px;" title="Oct-3/4 Antibody [Unconjugated]">Oct-3/4 Antibody<br> [Unconjugated]</a>    </div><div class="sub-header">AF1759</div> <div class="images_customers"><div id="ss_prev_cav6" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-6" data-cycle-prev="#ss_prev_cav6" data-cycle-next="#ss_next_cav6" data-cycle-slides="div.big_thumb_cust_container" data-index=6 ><div class="big_thumb_cust_container"> <a href="/products/oct-3-4-antibody_af1759" title="BG01V human embryonic stem cells were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. Oct‑3/4/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human/Mouse Oct‑3/4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1759) or control antibody (Catalog&amp;nbsp;# AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog&amp;nbsp;# BAF109). Immunocomplexes were captured using 50 μL of MagCellect Streptavidin Ferrofluid (Catalog&amp;nbsp;# MAG999) and DNA was purified using chelating resin solution. The nanog promoter was detected by standard PCR." class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images2/Oct-3_4_AF1759_Chromatin_Immunoprecipitation_11218.jpg" alt="Chromatin Immunoprecipitation (ChIP) Oct-3/4 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/oct-3-4-antibody_af1759" title="Alkaline phosphatase (ALPL) and Oct-3/4 were detected in human BG01V embryonic stem cells using 10 µg/mL Human/Mouse/Rat ALPL Monoclonal Antibody (Catalog # MAB1448) and 10 µg/mL Goat Anti-Human/Mouse Oct-3/4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1759). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for ALPL using the NorthernLights&amp;#8482; 557-conjugated Anti-Mouse IgG Secondary Antibody (pseudo-stained green; Catalog # NL007), and stained for Oct-3/4 using the NorthernLights 637-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL002). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images2/Oct-3_4_AF1759_Immunocytochemistry_7093.jpg" alt="Immunocytochemistry Oct-3/4 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/oct-3-4-antibody_af1759" title=" Simple Western lane view shows lysates of BG01V human embryonic stem cells and NTera‑2 human testicular embryonic carcinoma cell line, loaded at 0.2&amp;nbsp;mg/mL. A specific band was detected for Oct‑3/4 at approximately 50&amp;nbsp;kDa (as indicated) using 20&amp;nbsp;µg/mL of Goat Anti-Human/Mouse Oct‑3/4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1759) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog&amp;nbsp;# HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. " class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images2/Oct3_4_AF1759_Simple_Western_20183.jpg" alt="Simple Western Oct-3/4 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav6" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-6" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/oct-3-4-antibody_af1759#PublicationSection"> <div class="sprite_pubBook"></div> (77 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> ChIP, ICC, IP, Simple Western, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB120-16518"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd133-antibody_nb120-16518" style="overflow: hidden; width: 280px;" title="CD133 Antibody - BSA Free">CD133 Antibody -<br> BSA Free</a>    </div><div class="sub-header">NB120-16518</div> <div class="images_customers"><div id="ss_prev_cav7" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-7" data-cycle-prev="#ss_prev_cav7" data-cycle-next="#ss_next_cav7" data-cycle-slides="div.big_thumb_cust_container" data-index=7 ><div class="big_thumb_cust_container"> <a href="/products/cd133-antibody_nb120-16518" title="Immunohistochemistry-Paraffin: CD133 Antibody - BSA Free [NB120-16518] - Staining of CD133 in human hepatocarcinoma (HC) tissue. NB120-16518 was peroxidase-conjugated to the secondary antibody, followed by AEC staining." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images/CD133-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NB120-16518-img0002.jpg" alt="Immunohistochemistry-Paraffin CD133 Antibody - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd133-antibody_nb120-16518" title="Western Blot: CD133 Antibody - BSA Free [NB120-16518] - Predicted band size : 97 kDa recognizes 97 kDa human CD133 in Y79 cells. Band is at ~120 kDa due to protein glycosylation." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images/CD133-Antibody---BSA-Free-Western-Blot-NB120-16518-img0003.jpg" alt="Western Blot CD133 Antibody - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd133-antibody_nb120-16518" title="Chromatin Immunoprecipitation: CD133 Antibody - BSA Free [NB120-16518] - [NB 120-16518] - Staining CD133 in Bone Marrow Mononuclear Cells by Immunofluorescence." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images/CD133-Antibody---BSA-Free-Chromatin-Immunoprecipitation-NB120-16518-img0005.jpg" alt="Chromatin Immunoprecipitation CD133 Antibody - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav7" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-7" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd133-antibody_nb120-16518#PublicationSection"> <div class="sprite_pubBook"></div> (42 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Po, Rt</div><div class="tiny"><strong>Applications:</strong> ChIP, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF2018"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/sox2-antibody_af2018" style="overflow: hidden; width: 280px;" title="SOX2 Antibody [Unconjugated]">SOX2 Antibody<br> [Unconjugated]</a>    </div><div class="sub-header">AF2018</div> <div class="images_customers"><div id="ss_prev_cav8" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-8" data-cycle-prev="#ss_prev_cav8" data-cycle-next="#ss_next_cav8" data-cycle-slides="div.big_thumb_cust_container" data-index=8 ><div class="big_thumb_cust_container"> <a href="/products/sox2-antibody_af2018" title="Western blot shows lysates of D3 mouse embryonic stem cell line, NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for SOX2 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/SOX2_AF2018_Western_Blot_5161.jpg" alt="Western Blot SOX2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/sox2-antibody_af2018" title="BG01V human embryonic stem cells were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX2/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) or control antibody (AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (MAG999) and DNA was purified using chelating resin solution. Thenanogpromoter was detected by standard PCR." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/SOX2_AF2018_Chromatin_Immunoprecipitation_11224.jpg" alt="Chromatin Immunoprecipitation (ChIP) SOX2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/sox2-antibody_af2018" title="Simple Western lane view shows lysates of BG01V human embryonic stem cells and NTera-2 human testicular embryonic carcinoma cell line, loaded at 0.2 mg/mL. A specific band was detected for SOX2 at approximately 53 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/SOX2_AF2018_Simple_Western_16676.jpg" alt="Simple Western SOX2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav8" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-8" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/sox2-antibody_af2018#ReviewsSection"> <div class="sprite_4Stars"></div> (6 Reviews</a>) </div> <div class="tiny"> <a href="/products/sox2-antibody_af2018#PublicationSection"> <div class="sprite_pubBook"></div> (369 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> ChIP, ICC, IHC, Simple Western, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB100-79802"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/crm1-antibody_nb100-79802" style="overflow: hidden; width: 280px;" title="CRM1 Antibody">CRM1 Antibody</a>    </div><div class="sub-header">NB100-79802</div> <div class="images_customers"><div id="ss_prev_cav9" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-9" data-cycle-prev="#ss_prev_cav9" data-cycle-next="#ss_next_cav9" data-cycle-slides="div.big_thumb_cust_container" data-index=9 ><div class="big_thumb_cust_container"> <a href="/products/crm1-antibody_nb100-79802" title="Immunohistochemistry-Paraffin: CRM1 Antibody [NB100-79802] - Human lung cancer. Antibody: Affinity purified rabbit anti-CRM1 used at a dilution of 1:5,000 (0.2ug/ml). Detection: DAB" class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images/CRM1-Antibody-Immunohistochemistry-Paraffin-NB100-79802-img0023.jpg" alt="Immunohistochemistry-Paraffin CRM1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/crm1-antibody_nb100-79802" title="Immunohistochemistry-Paraffin: CRM1 Antibody [NB100-79802] - Mouse teratoma. Antibody: Affinity purified rabbit anti-CRM1 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB" class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images/CRM1-Antibody-Immunohistochemistry-Paraffin-NB100-79802-img0024.jpg" alt="Immunohistochemistry-Paraffin CRM1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/crm1-antibody_nb100-79802" title="Immunocytochemistry/Immunofluorescence: CRM1 Antibody [NB100-79802] - Association between Nup98-HoxA9 and CRM1 is critical for the Hox Gene activation mediated by Nup98-HoxA9. Top panel: Nup98-HoxA9 interacts and sequesters CRM1 onto Nup98-HoxA9 dots. HeLa cells were transfected with the EGFP-Nup98-HoxA9 expressing plasmid. After 24 hr, cells were fixed and stained with an anti-CRM1 antibody. Arrows indicate the cells transfected. Bottom panel: Nup98-HoxA9 ES cells were fixed and co-stained with anti-FLAG (M2) and anti-CRM1 antibodies. Merged image of FLAG (green) and CRM1 (red) is shown. Bar, 5um. Image collected and cropped by CiteAb from the following publication (https://elifesciences.org/articles/09540) licensed under a CC-BY license." class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images/CRM1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-79802-img0027.jpg" alt="Immunocytochemistry/ Immunofluorescence CRM1 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav9" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-9" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/crm1-antibody_nb100-79802#PublicationSection"> <div class="sprite_pubBook"></div> (16 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, IP, Simple Western, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB100-524"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/nod2-antibody-2d9_nb100-524" style="overflow: hidden; width: 280px;" title="NOD2 Antibody (2D9) - BSA Free">NOD2 Antibody<br> (2D9) - BSA Free</a>    </div><div class="sub-header">NB100-524</div> <div class="images_customers"><div id="ss_prev_cav10" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-10" data-cycle-prev="#ss_prev_cav10" data-cycle-next="#ss_next_cav10" data-cycle-slides="div.big_thumb_cust_container" data-index=10 ><div class="big_thumb_cust_container"> <a href="/products/nod2-antibody-2d9_nb100-524" title="Flow Cytometry: NOD2 Antibody (2D9) [NB100-524] - An intracellular stain was performed on Jurkat cells with NOD2 (2D9) antibody NB100-524APC (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images/NOD2-Antibody-2D9-Flow-Cytometry-NB100-524-img0014.jpg" alt="Flow Cytometry NOD2 Antibody (2D9) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/nod2-antibody-2d9_nb100-524" title="Flow Cytometry: NOD2 Antibody (2D9) [NB100-524] - An intracellular stain was performed on Jurkat cells with NOD2 (2D9) antibody NB100-524PE (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes.Both antibodies were conjugated to phycoerythrin." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images/NOD2-Antibody-2D9-Flow-Cytometry-NB100-524-img0015.jpg" alt="Flow Cytometry NOD2 Antibody (2D9) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/nod2-antibody-2d9_nb100-524" title="Immunohistochemistry-Frozen: NOD2 Antibody (2D9) [NB100-524] - Overlay of NOD2-DyLight 488 (green) with phase contrast of murine colon. Image from verified customer review." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images/NOD2-Antibody-2D9-Immunohistochemistry-Frozen-NB100-524-img0016.jpg" alt="Immunohistochemistry-Frozen NOD2 Antibody (2D9) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav10" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-10" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/nod2-antibody-2d9_nb100-524#ReviewsSection"> <div class="sprite_5Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/nod2-antibody-2d9_nb100-524#PublicationSection"> <div class="sprite_pubBook"></div> (26 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="7268-CT"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-ctla-4-fc-chimera-cho-expressed-cf_7268-ct" style="overflow: hidden; width: 280px;" title="CTLA-4 [Unconjugated]">CTLA-4<br> [Unconjugated]</a>    </div><div class="sub-header">7268-CT</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-11" data-cycle-prev="#ss_prev_cav11" data-cycle-next="#ss_next_cav11" data-cycle-slides="div.big_thumb_cust_container" data-index=11 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-ctla-4-fc-chimera-cho-expressed-cf_7268-ct" title="Recombinant Human CTLA-4 Fc Chimera (Catalog # 7268-CT) inhibits IL-2 secretion by stimulated Jurkat human acute Tcell leukemia cells. The&amp;nbsp;ED50 for this effect is 0.03-0.15 μg/mL whenstimulated with 1 μg/mL Recombinant Human B7‑1/CD80 Fc Chimera (Catalog&amp;nbsp;# 140-B1). " class="cust_viewed_11" > <img loading="lazy" src="https://images.novusbio.com/images2/CTLA4_7268CT_2293.jpg" alt="Bioactivity CTLA-4 [Unconjugated]" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-ctla-4-fc-chimera-cho-expressed-cf_7268-ct#PublicationSection"> <div class="sprite_pubBook"></div> (3 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-79843"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" style="overflow: hidden; width: 280px;" title="HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free">HLA DQ/DR/DP<br> Antibody (HLA-Pan/296 ...</a>    </div><div class="sub-header">NBP2-79843</div> <div class="images_customers"><div id="ss_prev_cav12" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-12" data-cycle-prev="#ss_prev_cav12" data-cycle-next="#ss_next_cav12" data-cycle-slides="div.big_thumb_cust_container" data-index=12 ><div class="big_thumb_cust_container"> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" title="Protein Array: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Analysis of Protein Array containing more than 19,000 full-length human proteins using HLA DQ/DR/DP Antibody (HLA-Pan/2967R). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5." class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images/HLA-DQ-DR-DP-Antibody-HLA-Pan-2967R-Azide-and-BSA-Free-Protein-Array-NBP2-79843-img0001.jpg" alt="Protein Array HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" title="Immunocytochemistry/Immunofluorescence: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Immunofluorescence staining of Raji cells using HLA DQ/DR/DP Antibody (HLA-Pan/2967R) followed by goat anti-rabbit IgG-CF488 (Green). Nuclei stained with RedDot (Red)." class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images/HLA-DQ-DR-DP-Antibody-HLA-Pan-2967R-Azide-and-BSA-Free-Immunocytochemistry-Immunofluorescence-NBP2-79843-img0002.jpg" alt="Immunocytochemistry/ Immunofluorescence HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" title="Western Blot: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Western Blot Analysis of Ramos cell lysate using HLA DQ/DR/DP Antibody (HLA-Pan/2967R)." class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images/HLA-DQ-DR-DP-Antibody-HLA-Pan-2967R-Azide-and-BSA-Free-Western-Blot-NBP2-79843-img0003.jpg" alt="Western Blot HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav12" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-12" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB110-58870"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/enolase-2-neuron-specific-enolase-antibody_nb110-58870" style="overflow: hidden; width: 280px;" title="Enolase 2/Neuron-specific Enolase Antibody">Enolase<br> 2/Neuron-specific Eno ...</a>    </div><div class="sub-header">NB110-58870</div> <div class="images_customers"><div id="ss_prev_cav13" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-13" data-cycle-prev="#ss_prev_cav13" data-cycle-next="#ss_next_cav13" data-cycle-slides="div.big_thumb_cust_container" data-index=13 ><div class="big_thumb_cust_container"> <a href="/products/enolase-2-neuron-specific-enolase-antibody_nb110-58870" title="Immunocytochemistry/Immunofluorescence: Enolase 2/Neuron-specific Enolase Antibody [NB110-58870] - Analysis of mixed cortical neuron-glial cell culture from E20 rat stained with rabbit pAb to neuron specific enolase (NSE), NB110-58870, dilution 1:500 in red, and costained with chicken pAb to GFAP, dilution 1:5,000 in green. The blue is Hoechst staining of nuclear DNA. the NSE antibody labels protein expressed in neuronal cells, while the GFAP antibody stains intermediate filaments in astrocytic and certain other glial cells." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/Enolase-2-Neuron-specific-Enolase-Antibody-Immunocytochemistry-Immunofluorescence-NB110-58870-img0006.jpg" alt="Immunocytochemistry/ Immunofluorescence Enolase 2/Neuron-specific Enolase Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/enolase-2-neuron-specific-enolase-antibody_nb110-58870" title="Western Blot: Enolase 2/Neuron-specific Enolase Antibody [NB110-58870] - Analysis of different tissue and cell lysates using rabbit pAb to neuron specific enolase (NSE), NB110-58870, dilution 1:5,000 in green: [1] protein standard (red), [2] rat brain, [3] rat spinal cord, [4] mouse brain, [5] mouse spinal cord, [6] NIH-3T3, [7] HEK293, [8] HeLa, [9] SH-SY5Y, and [10] C6 cells. A single band at about 47kDa corresponds to the NSE protein, seen only in extracts containing neurons ro neuronal lineage cells." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/Enolase-2-Neuron-specific-Enolase-Antibody-Western-Blot-NB110-58870-img0007.jpg" alt="Western Blot Enolase 2/Neuron-specific Enolase Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/enolase-2-neuron-specific-enolase-antibody_nb110-58870" title="Simple Western: Enolase 2/Neuron-specific Enolase Antibody [NB110-58870] - Simple Western lane view shows a specific band for Enolase 2/ Neuron specific enolase in 0.05 mg/ml of Human Brain lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/Enolase-2-Neuron-specific-Enolase-Antibody-Simple-Western-NB110-58870-img0004.jpg" alt="Simple Western Enolase 2/Neuron-specific Enolase Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav13" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-13" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/enolase-2-neuron-specific-enolase-antibody_nb110-58870#ReviewsSection"> <div class="sprite_5Stars"></div> (2 Reviews</a>) </div> <div class="tiny"> <a href="/products/enolase-2-neuron-specific-enolase-antibody_nb110-58870#PublicationSection"> <div class="sprite_pubBook"></div> (5 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, KD, Simple Western, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="DBD00"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/human-free-bdnf-quantikine-elisa-kit_dbd00" style="overflow: hidden; width: 280px;" title="BDNF [HRP]">BDNF [HRP]</a>    </div><div class="sub-header">DBD00</div> <div class="images_customers"><div id="ss_prev_cav14" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-14" data-cycle-prev="#ss_prev_cav14" data-cycle-next="#ss_next_cav14" data-cycle-slides="div.big_thumb_cust_container" data-index=14 ><div class="big_thumb_cust_container"> <a href="/products/human-free-bdnf-quantikine-elisa-kit_dbd00" title="" class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images2/DATA_BDNF_DBD00_ELISA_587.jpg" alt="N/A BDNF [HRP]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/human-free-bdnf-quantikine-elisa-kit_dbd00" title="" class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images2/DATA_BDNF_DBD00_ELISA_588.jpg" alt="N/A BDNF [HRP]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/human-free-bdnf-quantikine-elisa-kit_dbd00" title="" class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images2/BDNF_DBD00_ELISA_36.jpg" alt="N/A BDNF [HRP]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav14" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-14" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/human-free-bdnf-quantikine-elisa-kit_dbd00#PublicationSection"> <div class="sprite_pubBook"></div> (104 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ELISA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF4117"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd34-antibody_af4117" style="overflow: hidden; width: 280px;" title="CD34 Antibody [Unconjugated]">CD34 Antibody<br> [Unconjugated]</a>    </div><div class="sub-header">AF4117</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-15" data-cycle-prev="#ss_prev_cav15" data-cycle-next="#ss_next_cav15" data-cycle-slides="div.big_thumb_cust_container" data-index=15 ><div class="big_thumb_cust_container"> <a href="/products/cd34-antibody_af4117" title="CD34 was detected in perfusion fixed frozen sections of rat liver using 15 &amp;micro;g/mL Rat CD34 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4117) overnight at 4 &amp;deg;C. Tissue was stained with the Anti-Goat HRP-DAB Cell &amp; Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images2/CD34_AF4117_Immunohistochemistry_6824.jpg" alt="Immunohistochemistry CD34 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd34-antibody_af4117#ReviewsSection"> <div class="sprite_4Stars"></div> (3 Reviews</a>) </div> <div class="tiny"> <a href="/products/cd34-antibody_af4117#PublicationSection"> <div class="sprite_pubBook"></div> (37 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Rt</div><div class="tiny"><strong>Applications:</strong> IHC, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP3-05513"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/methionine-aminopeptidase-2-metap2-antibody_nbp3-05513" style="overflow: hidden; width: 280px;" title="Methionine Aminopeptidase 2/METAP2 Antibody">Methionine<br> Aminopeptidase 2/META ...</a>    </div><div class="sub-header">NBP3-05513</div> <div class="images_customers"><div id="ss_prev_cav16" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-16" data-cycle-prev="#ss_prev_cav16" data-cycle-next="#ss_next_cav16" data-cycle-slides="div.big_thumb_cust_container" data-index=16 ><div class="big_thumb_cust_container"> <a href="/products/methionine-aminopeptidase-2-metap2-antibody_nbp3-05513" title="Immunocytochemistry/Immunofluorescence: Methionine Aminopeptidase 2/METAP2 Antibody [NBP3-05513] - Staining of human cell line U-2 OS shows localization to plasma membrane &amp; cytosol." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/Methionine-Aminopeptidase-2-METAP2-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-05513-img0001.jpg" alt="Immunocytochemistry/ Immunofluorescence Methionine Aminopeptidase 2/METAP2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/methionine-aminopeptidase-2-metap2-antibody_nbp3-05513" title="Immunohistochemistry-Paraffin: Methionine Aminopeptidase 2/METAP2 Antibody [NBP3-05513] - Staining of human lymph node shows strong cytoplasmic positivity in germinal center cells." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/Methionine-Aminopeptidase-2-METAP2-Antibody-Immunohistochemistry-Paraffin-NBP3-05513-img0002.jpg" alt="Immunohistochemistry-Paraffin Methionine Aminopeptidase 2/METAP2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/methionine-aminopeptidase-2-metap2-antibody_nbp3-05513" title="Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody [NBP3-05513] - Analysis in U2OS cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-METAP2 antibody. Remaining relative intensity is presented." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/Methionine-Aminopeptidase-2-METAP2-Antibody-Western-Blot-NBP3-05513-img0003.jpg" alt="Western Blot Methionine Aminopeptidase 2/METAP2 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav16" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-16" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP1-72042"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/doublecortin-antibody_nbp1-72042" style="overflow: hidden; width: 280px;" title="Doublecortin Antibody">Doublecortin<br> Antibody</a>    </div><div class="sub-header">NBP1-72042</div> <div class="images_customers"><div id="ss_prev_cav17" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-17" data-cycle-prev="#ss_prev_cav17" data-cycle-next="#ss_next_cav17" data-cycle-slides="div.big_thumb_cust_container" data-index=17 ><div class="big_thumb_cust_container"> <a href="/products/doublecortin-antibody_nbp1-72042" title="Western Blot: Doublecortin Antibody [NBP1-72042] - staining of Mouse fetal Brain lysate (35 ug protein in RIPA buffer). Antibody at 0.01 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/Doublecortin-Antibody-Western-Blot-NBP1-72042-img0001.jpg" alt="Western Blot Doublecortin Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/doublecortin-antibody_nbp1-72042" title="Immunocytochemistry/Immunofluorescence: Doublecortin Antibody [NBP1-72042] - Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (5 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL)." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/Doublecortin-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-72042-img0005.jpg" alt="Immunocytochemistry/ Immunofluorescence Doublecortin Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/doublecortin-antibody_nbp1-72042" title="Immunocytochemistry/Immunofluorescence: Doublecortin Antibody [NBP1-72042] - Immunofluorescence analysis of paraformaldehyde fixed KNRK cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL)." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/Doublecortin-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-72042-img0007.jpg" alt="Immunocytochemistry/ Immunofluorescence Doublecortin Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav17" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-17" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/doublecortin-antibody_nbp1-72042#PublicationSection"> <div class="sprite_pubBook"></div> (4 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, PEP-ELISA, WB</div> </div> </div> </div></div> </div><div id="cav_next"><div class="sprite_rightArrow"></div></div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_reviews-publications"> <a id="reviews-publications"></a><a id="PublicationSection"></a><h2 class="greyHead2">Publications for Nestin Antibody (MAB1259)(161)</h2><div class="ds_info"> <div>We have publications tested in 4 confirmed species: Human, Mouse, Rat, Xenograft.<br /><br />We have publications tested in 11 applications: Bioassay, Cell Culture, Flow Cytometry, ICC, IF, IHC, IHC-Fr, IHC-P, Immunocytochemistry, Immunohistochemistry, Western Blot.<br /><br /><div class="align-right"> <button class="greybutton btn_width" name="novusreview" onclick="window.location='/publications'"; >Submit a Publication</button><br /> </div> </div><div> <div class="filterParent"> <div class="publications_filterList" id="pubapp"> <div class="blueHead">Filter By Application</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Bioassay"> <div style="display:inline;">Bioassay</div> (1)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Cell Culture"> <div style="display:inline;">Cell Culture</div> (1)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Flow Cytometry"> <div style="display:inline;">Flow Cytometry</div> (10)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="ICC"> <div style="display:inline;">ICC</div> (66)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="IF"> <div style="display:inline;">IF</div> (2)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="IHC"> <div style="display:inline;">IHC</div> (16)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="IHC-Fr"> <div style="display:inline;">IHC-Fr</div> (4)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="IHC-P"> <div style="display:inline;">IHC-P</div> (8)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Immunocytochemistry"> <div style="display:inline;">Immunocytochemistry</div> (4)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Immunohistochemistry"> <div style="display:inline;">Immunohistochemistry</div> (2)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Western Blot"> <div style="display:inline;">Western Blot</div> (8)</div><div class="filter_clear" data-type="publication" data-filter="application">All Applications</div></div> <div class="publications_filterList" id="pubspec"> <div class="blueHead">Filter By Species</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Human"> <div style="display:inline;">Human</div> (100)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Mouse"> <div style="display:inline;">Mouse</div> (8)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Rat"> <div style="display:inline;">Rat</div> (1)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Xenograft"> <div style="display:inline;">Xenograft</div> (2)</div><div class="filter_clear" data-type="publication" data-filter="species">All Species</div></div> </div></div> <div class="clear"></div> <div id="publications_list">Showing Publications 1 - <span id="appcnt">10</span> of 161. <a class="pubs_showall">Show All 161 Publications.</a> <a class="pubs_collapse" style="display:none;">Collapse Publications.</a><table class="wide lightPad tablesorter" id="publications_list_table"> <thead> <tr> <th>Publications using MAB1259</th> <th>Applications</th> <th>Species</th> </tr> </thead> <tbody><tr class="lined revfil firstten" data-application="Immunocytochemistry" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39178824" target="_blank" rel="nofollow"> Alexanian, AR;Sorokin, A;Duersteler, M; Dopaminergic progenitors generated by small molecule approach survived, integrated, and promoted functional recovery in (6-OHDA) mouse model of Parkinson's disease Journal of the neurological sciences 2024-08-20 [PMID: 39178824] (Immunocytochemistry, Human) </a></td> <td valign="top">Immunocytochemistry</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Immunohistochemistry" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/39039193" target="_blank" rel="nofollow"> Gupta, R;Dittmeier, M;Wohlleben, G;Nickl, V;Bischler, T;Luzak, V;Wegat, V;Doll, D;Sodmann, A;Bady, E;Langlhofer, G;Wachter, B;Havlicek, S;Gupta, J;Horn, E;Lüningschrör, P;Villmann, C;Polat, B;Wischhusen, J;Monoranu, CM;Kuper, J;Blum, R; Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene Cancer gene therapy 2024-07-22 [PMID: 39039193] (Immunohistochemistry, Human) </a></td> <td valign="top">Immunohistochemistry</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Flow Cytometry" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38905814" target="_blank" rel="nofollow"> Juchem, M;Lehmann, N;Behrens, YL;Bär, C;Thum, T;Hoepfner, J; CRISPR/Cas9-based GLA knockout to generate the female Fabry disease human induced pluripotent stem cell line MHHi001-A-15 Stem cell research 2024-06-20 [PMID: 38905814] (Flow Cytometry, Human) </a></td> <td valign="top">Flow Cytometry</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Flow Cytometry, Immunocytochemistry" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38552356" target="_blank" rel="nofollow"> Jahn, C;Juchem, M;Sonnenschein, K;Gietz, A;Buchegger, T;Lachmann, N;Göhring, G;Behrens, YL;Bär, C;Thum, T;Hoepfner, J; Generation of human induced pluripotent stem cell line MHHi029-A from a male Fabry disease patient carrying c.959A &gt; T mutation Stem cell research 2024-03-24 [PMID: 38552356] (Flow Cytometry, Immunocytochemistry, Human) </a></td> <td valign="top">Flow Cytometry, Immunocytochemistry</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Immunohistochemistry" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38374263" target="_blank" rel="nofollow"> Frenz-Wiessner, S;Fairley, SD;Buser, M;Goek, I;Salewskij, K;Jonsson, G;Illig, D;Zu Putlitz, B;Petersheim, D;Li, Y;Chen, PH;Kalauz, M;Conca, R;Sterr, M;Geuder, J;Mizoguchi, Y;Megens, RTA;Linder, MI;Kotlarz, D;Rudelius, M;Penninger, JM;Marr, C;Klein, C; Generation of complex bone marrow organoids from human induced pluripotent stem cells Nature methods 2024-02-19 [PMID: 38374263] (Immunohistochemistry, Human) </a></td> <td valign="top">Immunohistochemistry</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Immunocytochemistry" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38191669" target="_blank" rel="nofollow"> Gao, L;Behrens, A;Rodschinka, G;Forcelloni, S;Wani, S;Strasser, K;Nedialkova, DD; Selective gene expression maintains human tRNA anticodon pools during differentiation Nature cell biology 2024-01-08 [PMID: 38191669] (Immunocytochemistry, Human) </a></td> <td valign="top">Immunocytochemistry</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="IHC" data-species="Xenograft"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38136258" target="_blank" rel="nofollow"> Zimmer, N;Trzeciak, ER;Müller, A;Licht, P;Sprang, B;Leukel, P;Mailänder, V;Sommer, C;Ringel, F;Tuettenberg, J;Kim, E;Tuettenberg, A; Nuclear Glycoprotein A Repetitions Predominant (GARP) Is a Common Trait of Glioblastoma Stem-like Cells and Correlates with Poor Survival in Glioblastoma Patients Cancers 2023-12-05 [PMID: 38136258] (IHC, Xenograft) </a></td> <td valign="top">IHC</td> <td valign="top">Xenograft</td> </tr><tr class="lined revfil firstten" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37730545" target="_blank" rel="nofollow"> Patrycja Mulica, Carmen Venegas, Zied Landoulsi, Katja Badanjak, Sylvie Delcambre, Maria Tziortziou et al. Comparison of two protocols for the generation of iPSC-derived human astrocytes Biol Proced Online 2023-09-20 [PMID: 37730545] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil firstten" data-application="" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37447406" target="_blank" rel="nofollow"> Garrudo, FFF;Filippone, G;Resina, L;Silva, JC;Barbosa, F;Ferreira, LFV;Esteves, T;Marques, AC;Morgado, J;Ferreira, FC; Production of Blended Poly(acrylonitrile): Poly(ethylenedioxythiophene):Poly(styrene sulfonate) Electrospun Fibers for Neural Applications Polymers 2023-06-21 [PMID: 37447406] (Human) </a></td> <td valign="top"></td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37396785" target="_blank" rel="nofollow"> Jia-jun Qiu, Yan-na Liu, Hao Wei, Fanyi Zeng, Jing-bin Yan Single-cell RNA sequencing of neural stem cells derived from human trisomic iPSCs reveals the abnormalities during neural differentiation of Down syndrome Frontiers in Molecular Neuroscience 6/15/2023 [PMID: 37396785] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="Immunocytochemistry" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37296600" target="_blank" rel="nofollow"> Tam, KW;Wong, CY;Wu, KL;Lam, G;Liang, X;Wong, WT;Li, MT;Liu, WY;Cai, S;Shea, GK;Shum, DK;Chan, YS; IPSC-Derived Sensory Neurons Directing Fate Commitment of Human BMSC-Derived Schwann Cells: Applications in Traumatic Neural Injuries Cells 2023-05-25 [PMID: 37296600] (Immunocytochemistry, Human) </a></td> <td valign="top">Immunocytochemistry</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37272619" target="_blank" rel="nofollow"> Dell'Amico, C;Angulo Salavarria, MM;Takeo, Y;Saotome, I;Dell'Anno, MT;Galimberti, M;Pellegrino, E;Cattaneo, E;Louvi, A;Onorati, M; Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors eLife 2023-06-05 [PMID: 37272619] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37170124" target="_blank" rel="nofollow"> Karapurkar JK, Kim MS, Colaco JC et al. CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis Journal of experimental & clinical cancer research : CR 2023-05-12 [PMID: 37170124]<br /><br />Details:<br />IHC-P 1:100 </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37082206" target="_blank" rel="nofollow"> KN Eigenhuis, HB Somsen, M van der Kr, H Smeenk, AL Korporaal, SA Kushner, FMS de Vrij, DLC van den Be A simplified protocol for the generation of cortical brain organoids Frontiers in Cellular Neuroscience, 2023-04-04;17(0):1114420. 2023-04-04 [PMID: 37082206] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="IHC" data-species="Rat"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36429025" target="_blank" rel="nofollow"> G Rastoldo, I Watabe, A Lapotre, A Tonetto, A López-Juár, B Tighilet Vestibular Nuclei: A New Neural Stem Cell Niche? Cells, 2022-11-14;11(22):. 2022-11-14 [PMID: 36429025] (IHC, Rat) </a></td> <td valign="top">IHC</td> <td valign="top">Rat</td> </tr><tr class="lined revfil hidden" data-application="Western Blot" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36417870" target="_blank" rel="nofollow"> EJ Kim, JY Kim, SO Kim, N Hong, SH Choi, MG Park, J Jang, SW Ham, S Seo, SY Lee, K Lee, HJ Jeong, SJ Kim, S Jeong, K Min, SC Kim, X Jin, SH Kim, SH Kim, H Kim The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2 Cell Reports, 2022-11-22;41(8):111626. 2022-11-22 [PMID: 36417870] (Western Blot, Human) </a></td> <td valign="top">Western Blot</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36305367" target="_blank" rel="nofollow"> Wischhof L, Lee HM, Tutas J et al. BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation The EMBO Journal 2022-12-01 [PMID: 36305367] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36140726" target="_blank" rel="nofollow"> Jing-Jing Sun, Qin Cai, Miao Xu, Yan-Na Liu, Wan-Rui Li, Juan Li et al. Loss of Protein Function Causing Severe Phenotypes of Female-Restricted Wieacker Wolff Syndrome due to a Novel Nonsense Mutation in the ZC4H2 Gene Genes (Basel) 8/29/2022 [PMID: 36140726] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="IHC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36123372" target="_blank" rel="nofollow"> L Adnani, J Kassouf, B Meehan, C Spinelli, N Tawil, I Nakano, J Rak Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells Nature Communications, 2022-09-19;13(1):5494. 2022-09-19 [PMID: 36123372] (IHC, Human) </a></td> <td valign="top">IHC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="IHC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35869235" target="_blank" rel="nofollow"> J Brás, D Henriques, R Moreira, MM Santana, R Silva-Pedr, D Adão, S Braz, AR Álvaro, LP de Almeida, LS Mendonça Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases Scientific Reports, 2022-07-22;12(1):12513. 2022-07-22 [PMID: 35869235] (IHC, Human) </a></td> <td valign="top">IHC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35806277" target="_blank" rel="nofollow"> RR Khadim, RK Vadivelu, T Utami, FG Torizal, M Nishikawa, Y Sakai Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCs International Journal of Molecular Sciences, 2022-06-30;23(13):. 2022-06-30 [PMID: 35806277] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35728441" target="_blank" rel="nofollow"> YH Chen, PS Huang, MH Wen, M Pan, DF Lee, TY Chen Generation of a homozygous knock-in human embryonic stem cell line expressing mEos4b-tagged CTR1 Oncogene, 2022-06-14;63(0):102845. 2022-06-14 [PMID: 35728441] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35721463" target="_blank" rel="nofollow"> Elena Fdez, Jesús Madero-Pérez, Antonio J. Lara Ordóñez, Yahaira Naaldijk, Rachel Fasiczka, Ana Aiastui et al. Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement iScience 2022-06-17 [PMID: 35721463] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35573835" target="_blank" rel="nofollow"> Elisa Degl’Innocenti, Tino Emanuele Poloni, Valentina Medici, Luca Recupero, Claudia Dell’Amico, Eleonora Vannini et al. Centrin 2: A Novel Marker of Mature and Neoplastic Human Astrocytes Frontiers in Cellular Neuroscience 2022-04-29 [PMID: 35573835] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35474694" target="_blank" rel="nofollow"> Fabio Bertan, Lena Wischhof, Enzo Scifo, Mihaela Guranda, Joshua Jackson, Anaïs Marsal-Cots et al. Comparative analysis of CI- and CIV-containing respiratory supercomplexes at single-cell resolution Cell Reports Methods 2021-05-24 [PMID: 35474694] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35455950" target="_blank" rel="nofollow"> L Schwarz, JC Fitzgerald Steady-State Levels of Miro1 Linked to Phosphorylation at Serine 156 and Mitochondrial Respiration in Dopaminergic Neurons Cells, 2022-04-08;11(8):. 2022-04-08 [PMID: 35455950] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35453044" target="_blank" rel="nofollow"> M Tisch, M Carmen De, M Suarez-Cub, C Fauth, M Defrancesc, J Zschocke, K Günther, F Edenhofer Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene Stem Cell Research, 2022-04-09;61(0):102784. 2022-04-09 [PMID: 35453044] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35442746" target="_blank" rel="nofollow"> YW Cho, S Jee, IR Suhito, JH Lee, CG Park, KM Choi, TH Kim Single metal-organic framework-embedded nanopit arrays: A new way to control neural stem cell differentiation Science Advances, 2022-04-20;8(16):eabj7736. 2022-04-20 [PMID: 35442746] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35345594" target="_blank" rel="nofollow"> Aida Amador-Álvarez, María A. Gómez-Muñoz, Ismael Rodríguez-Prieto, Ricardo Pardal, Francisco M. Vega A protocol to enrich in undifferentiated cells from neuroblastoma tumor tissue samples and cell lines STAR Protocols 2022-06-01 [PMID: 35345594] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35273362" target="_blank" rel="nofollow"> K Kaushal, EJ Kim, A Tyagi, JK Karapurkar, S Haq, HS Jung, KS Kim, S Ramakrishn Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis Cell Death and Differentiation, 2022-03-10;0(0):. 2022-03-10 [PMID: 35273362] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="IF, IHC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35183162" target="_blank" rel="nofollow"> B Polat, G Wohlleben, R Kosmala, D Lisowski, F Mantel, V Lewitzki, M Löhr, R Blum, P Herud, M Flentje, CM Monoranu Differences in stem cell marker and osteopontin expression in primary and recurrent glioblastoma Cancer Cell International, 2022-02-19;22(1):87. 2022-02-19 [PMID: 35183162] (IF, IHC, Human) </a></td> <td valign="top">IF, IHC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35148180" target="_blank" rel="nofollow"> B Bohl, A Jabali, J Ladewig, P Koch Asymmetric Notch activity by differential inheritance of lysosomes in human neural stem cells Science Advances, 2022-02-11;8(6):eabl5792. 2022-02-11 [PMID: 35148180] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35029059" target="_blank" rel="nofollow"> You Y, Muraoka S, Jedrychowski MP et al. Human neural cell type-specific�extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain Journal of Extracellular Vesicles 2022-01-13 [PMID: 35029059] </a></td> <td valign="top"></td> <td valign="top"></td> </tr><tr class="lined revfil hidden" data-application="" data-species=""> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/34948016" target="_blank" rel="nofollow"> Adrian Odrzywolski, Bożena Jarosz, Michał Kiełbus, Ilona Telejko, Dominik Ziemianek, Sebastian Knaga et al. 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Sci., 2008-08-15;49(12):5325-31. 2008-08-15 [PMID: 18708614] (IHC-P, Human) </a></td> <td valign="top">IHC-P</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/18619850" target="_blank" rel="nofollow"> Hattermann K, Ludwig A, Gieselmann V, Held-Feindt J, Mentlein R The chemokine CXCL16 induces migration and invasion of glial precursor cells via its receptor CXCR6. Mol. Cell. Neurosci., 2008-04-10;39(1):133-41. 2008-04-10 [PMID: 18619850] (ICC, Mouse) </a></td> <td valign="top">ICC</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/18450476" target="_blank" rel="nofollow"> Sun Y, Pollard S, Conti L, Toselli M, Biella G, Parkin G, Willatt L, Falk A, Cattaneo E, Smith A Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture. Mol. Cell. Neurosci., 2008-03-18;38(2):245-58. 2008-03-18 [PMID: 18450476] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/18420830" target="_blank" rel="nofollow"> Ladewig J, Koch P, Endl E, Meiners B, Opitz T, Couillard-Despres S, Aigner L, Brustle O Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons. Stem Cells, 2008-04-17;26(7):1705-12. 2008-04-17 [PMID: 18420830] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17709197" target="_blank" rel="nofollow"> Ishii J, Natsume A, Wakabayashi T, Takeuchi H, Hasegawa H, Kim SU, Yoshida J The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress. Neurosci. Lett., 2007-08-03;423(3):225-30. 2007-08-03 [PMID: 17709197] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17673180" target="_blank" rel="nofollow"> Inagaki A, Soeda A, Oka N, Kitajima H, Nakagawa J, Motohashi T, Kunisada T, Iwama T Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture conditions. Biochem. Biophys. Res. Commun., 2007-07-18;361(3):586-92. 2007-07-18 [PMID: 17673180] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17588481" target="_blank" rel="nofollow"> Neuhoff S, Moers J, Rieks M, Grunwald T, Jensen A, Dermietzel R, Meier C Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro. Exp. Hematol., 2007-07-01;35(7):1119-31. 2007-07-01 [PMID: 17588481] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17272497" target="_blank" rel="nofollow"> Shin S, Sun Y, Liu Y, Khaner H, Svant S, Cai J, Xu QX, Davidson BP, Stice SL, Smith AK, Goldman SA, Reubinoff BE, Zhan M, Rao MS, Chesnut JD Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue. Stem Cells, 2007-02-01;25(5):1298-306. 2007-02-01 [PMID: 17272497] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Flow Cytometry, ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17052254" target="_blank" rel="nofollow"> Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages. Br. J. Haematol., 2006-12-01;135(5):703-14. 2006-12-01 [PMID: 17052254] (Flow Cytometry, ICC, Human) </a></td> <td valign="top">Flow Cytometry, ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17027979" target="_blank" rel="nofollow"> Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells. FEBS Lett., 2006-10-02;580(25):5869-74. 2006-10-02 [PMID: 17027979] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC, Western Blot" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16642511" target="_blank" rel="nofollow"> Sheen VL, Ferland RJ, Harney M, Hill RS, Neal J, Banham AH, Brown P, Chenn A, Corbo J, Hecht J, Folkerth R, Walsh CA Impaired proliferation and migration in human Miller-Dieker neural precursors. Ann. Neurol., 2006-07-01;60(1):137-44. 2006-07-01 [PMID: 16642511] (ICC, Western Blot, Human) </a></td> <td valign="top">ICC, Western Blot</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16100006" target="_blank" rel="nofollow"> Shin S, Mitalipova M, Noggle S, Tibbitts D, Venable A, Rao R, Stice SL Long-term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions. Stem Cells, 2005-08-11;24(1):125-38. 2005-08-11 [PMID: 16100006] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15486935" target="_blank" rel="nofollow"> Gerecht-Nir S, Cohen S, Ziskind A, Itskovitz-Eldor J Three-dimensional porous alginate scaffolds provide a conducive environment for generation of well-vascularized embryoid bodies from human embryonic stem cells. Biotechnol. Bioeng., 2004-11-05;88(3):313-20. 2004-11-05 [PMID: 15486935] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Flow Cytometry, ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15351504" target="_blank" rel="nofollow"> Ni HT, Hu S, Sheng WS, Olson JM, Cheeran MC, Chan AS, Lokensgard JR, Peterson PK High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells. Brain Res. Dev. Brain Res., 2004-09-17;152(2):159-69. 2004-09-17 [PMID: 15351504] (Flow Cytometry, ICC, Human) </a></td> <td valign="top">Flow Cytometry, ICC</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="ICC" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15153604" target="_blank" rel="nofollow"> Segev H, Fishman B, Ziskind A, Shulman M, Itskovitz-Eldor J Differentiation of human embryonic stem cells into insulin-producing clusters. Stem Cells, 2004-01-01;22(3):265-74. 2004-01-01 [PMID: 15153604] (ICC, Human) </a></td> <td valign="top">ICC</td> <td valign="top">Human</td> </tr><tr><td colspan="3" align="center"> <a class="pubs_showall">Show All 161 Publications.</a> <a class="pubs_collapse" style="display:none;">Collapse Publications.</a> </td></tr></tbody> </table> </div> </div><a id="ReviewsSection"></a> <h2 class="greyHead2">Reviews for <span>Nestin Antibody (MAB1259)</span> (3) <span style="display:none;">4.3</span><span style="display:none;">3</span></h2> <div class="ds_info"> <div class="bottom15"> <strong>Average Rating: 4.3</strong> <div class="dsSprite_stars4"></div> (Based on 3 reviews) </div> <div><div class="ds_info">We have 3 reviews tested in 1 species: Human.</div> <div class="align-right"> <button class="greybutton btn_width" id="novusreview" name="novusreview" onclick="window.location='/reviews/MAB1259'"; >Submit a Review</button><br /> </div> </div> <div class="blueHead"><strong>Reviews using MAB1259:</strong></div> <div class="filterParent"><div class="reviews_filterList"> <div class="blueHead">Filter by Applications</div><div class="filter_line"> <input type="checkbox" value="application" class="review_filterCheckbox" data-filter="ICC"> <div style="display:inline;">ICC</div> (1)</div><div class="filter_line"> <input type="checkbox" value="application" class="review_filterCheckbox" data-filter="Immunofluorescence - paraffin"> <div style="display:inline;">Immunofluorescence - paraffin</div> (1)</div><div class="filter_line"> <input type="checkbox" value="application" class="review_filterCheckbox" data-filter="IF"> <div style="display:inline;">IF</div> (1)</div><div class="filter_clear" data-type="review" data-filter="application">All Applications</div></div> <div class="reviews_filterList"> <div class="blueHead">Filter by Species</div><div class="filter_line"> <input type="checkbox" value="species" class="review_filterCheckbox" data-filter="Human"> <div style="display:inline;">Human</div> (3)</div><div class="filter_clear" data-type="review" data-filter="species">All Species</div></div></div><div id="reviews_list"> <table class="wide lightPad tablesorter" id="reviews_list_table"> <thead> <tr> <th>Images</th> <th>Ratings</th> <th>Applications</th> <th>Species</th> <th>Date</th> <th>Details</th> </tr> </thead> <tbody><tr class="top-lined revfil" data-rating="Excellent" data-application="ICC" data-species="Human"> <td><a href="https://www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_58396_0_0.jpg" title="Human neural stem cells" class="colorbox" title="Immunocytochemistry" > <img loading="lazy" src="https://www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_58396_0_0.jpg" class="reviews_imageBorder" width="75" alt="Immunocytochemistry Nestin MAB1259" /> <br/><span class="enlarge" href="#"><div class="dsSprite_magGlass"></div> Enlarge</span></a><meta content="02/10/2022" /> </td> <td> <span style="display:none;">5</span> <div class="dsSprite_stars5" content="5"></div> <div class="revby">reviewed by:<br />Verified Customer</div> </td> <td title="Immunocytochemistry">ICC</td> <td>Human</td> <td>02/10/2022</td> <td align="left"> <div class="dsSprite_expandReviews"><div class="expandReviewData">View</div></div> <div class="reviews_showMoreContent"> <div class="reviews_showMoreContentInner"><h2 class="greyHead">Summary</h2> <table class="even wide top"><tr><td class="text_bold">Application</td><td>Immunocytochemistry</td></tr><tr><td class="text_bold">Sample Tested</td><td>Neural stem cells</td></tr><tr><td class="text_bold">Species</td><td>Human</td></tr><tr><td class="text_bold">Lot</td><td>196908</td></tr></table> </div> </div> </td> </tr><tr class="top-lined revfil" data-rating="Very Good" data-application="Immunofluorescence - paraffin" data-species="Human"> <td><a href="https://www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_46716_0_0_0.png" title="Glioblastoma multiforme stained with anti-nestin antibody 1:100" class="colorbox" title="Other" > <img loading="lazy" src="https://www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_46716_0_0_0.png" class="reviews_imageBorder" width="75" alt="Other Nestin MAB1259" /> <br/><span class="enlarge" href="#"><div class="dsSprite_magGlassBlue"></div> Enlarge</span></a><meta content="03/09/2019" /> </td> <td> <span style="display:none;">4</span> <div class="dsSprite_stars4" content="4"></div> <div class="revby">reviewed by:<br />Verified Customer</div> </td> <td title="Other">Immunofluorescence - paraffin</td> <td>Human</td> <td>03/09/2019</td> <td align="left"> <div class="dsSprite_expandReviews"><div class="expandReviewData">View</div></div> <div class="reviews_showMoreContent"> <div class="reviews_showMoreContentInner"><h2 class="greyHead">Summary</h2> <table class="even wide top"><tr><td class="text_bold">Application</td><td>Other</td></tr><tr><td class="text_bold">Sample Tested</td><td>human glioblastoma</td></tr><tr><td class="text_bold">Species</td><td>Human</td></tr><tr><td class="text_bold">Lot</td><td>I don't have it any more</td></tr></table><h2 class="greyHead">Comments</h2> <table class="even wide top"><tr><td class="text_bold">Comments</td><td>pH9 heat induced antigen retrieval</td></tr></table> </div> </div> </td> </tr><tr class="top-lined revfil" data-rating="Very Good" data-application="IF" data-species="Human"> <td> <meta content="02/04/2015" /> </td> <td> <span style="display:none;">4</span> <div class="dsSprite_stars4" content="4"></div> <div class="revby">reviewed by:<br />Verified Customer</div> </td> <td title="Immunofluorescence">IF</td> <td>Human</td> <td>02/04/2015</td> <td align="left"> <div class="dsSprite_expandReviews"><div class="expandReviewData">View</div></div> <div class="reviews_showMoreContent"> <div class="reviews_showMoreContentInner"><h2 class="greyHead">Summary</h2> <table class="even wide top"><tr><td class="text_bold">Application</td><td>Immunofluorescence</td></tr><tr><td class="text_bold">Sample Tested</td><td>See PMID 24213561</td></tr><tr><td class="text_bold">Species</td><td>Human</td></tr></table> </div> </div> </td> </tr></tbody> </table> </div><br /> </div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_protocols-faqs"> <a id="protocols-faqs"></a><h2 class="greyHead2">FAQs for Nestin Antibody (MAB1259) (0)</h2> <a id="faqs"></a> <div class="ds_info">There are no specific FAQs related to this product. Read our general <a href="/support/faqs.html">customer & technical service FAQs.</a> </div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_supportresearch"> <a id="supportresearch"></a><table cellpadding="0" cellspacing="0"><tr><td valign="top" class="width50"> <h2 class="greyHead2">Secondary Antibodies</h2> <a id="secondaryantibodies"></a> <div class="ds_info"> <ul class="information-list"><li><a href="/product-type/secondary-antibodies?species=Mouse&facet_conjugate=HRP">Anti-Mouse HRP Labeled Antibodies</a></li><li><a href="/product-type/secondary-antibodies?species=Mouse&facet_conjugate=FITC">Anti-Mouse FITC Labeled Antibodies</a></li><li><a href="/product-type/secondary-antibodies?species=Mouse&facet_conjugate=Biotin">Anti-Mouse Biotin Labeled Antibodies</a></li><li> </li> <li><a href="/product-type/secondary-antibodies#fq=species%3A%22Mouse%22">View all of our anti-Mouse Secondary Antibodies</a></li> </ul> </div></td><td width="5"> </td><td valign="top"> <h2 class="greyHead2" >Isotype Controls</h2> <a id="isotypecontrols"></a> <div class="ds_info"> <ul class="ds_noDotList"><li><a href="/product-type/isotype-controls#fq=species%3A%22Mouse%22">Mouse Isotype Controls</a></li><li> </li> <li><a href="/product-type/isotype-controls">View all of our Isotype Control Products</a></li> </div></td></tr></table><h2 class="greyHead2">Additional Nestin Products</h2> <a id="addtlalphaprods"></a> <div class="ds_info"> <div> <span style="display:none;">Array MAB1259</span> <ul class="ds_noDotList"><li> <a href="/primary-antibodies/nestin">Nestin Antibodies</a></li><li> <a href="/elisa-kits/nestin">Nestin ELISA Kits</a></li><li> <a href="/proteins/nestin">Nestin Proteins</a></li></ul> </div> </div><table cellpadding="0" cellspacing="0" class="width100"><tr></tr></table><table cellpadding="0" cellspacing="0" class="width100"><tr></tr></table><h2 class="greyHead2">Blogs on Nestin. </h2> <a id="blogsect"></a> <div class="ds_info"><a href="/antibody-news/tag/nestin">Check out the latest blog posts on Nestin</a>.</div> <div class="ds_info"> <table id="blogs_list_table"> <tbody> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/deriving-neural-precursor-cells-from-human-induced-pluripotent-stem-cells">Deriving neural precursor cells from human induced pluripotent stem cells</a></strong><br/> <span> By Jennifer Sokolowski, MD, PhD.Human induced pluripotent stem cells (iPSCs) can be used to create models of human organ systems and are useful for a) ascertaining the mechanisms underlying pathological conditions...  <a href="/antibody-news/deriving-neural-precursor-cells-from-human-induced-pluripotent-stem-cells">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antibodies/nestin-investigating-the-link-between-new-brain-cells-and-depression">Nestin: Investigating the Link Between New Brain Cells and Depression</a></strong><br/> <span>Clinical depression (also known as major depressive disorder or MDD) affects many people, but the biological processes that cause it (and are influenced by its treatments) are not well understood. Adult neurogenesis is a newly emerging field that coul...  <a href="/antibody-news/antibodies/nestin-investigating-the-link-between-new-brain-cells-and-depression">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antibodies/nestin-antibody-products-in-neuronal-cancer-research">Nestin Antibody Products in Neuronal Cancer Research</a></strong><br/> <span>Nestin is a large class Vl intermediate filament protein predominantly expressed in the neuroepithelial stem cells of the embryonic central nervous system, although recent nestin antibody studies have shown it expressed in other cell types, including ...  <a href="/antibody-news/antibodies/nestin-antibody-products-in-neuronal-cancer-research">Read full blog post.</a></span><br /><br /> </td> </tr></tbody> </table> </div> <div class="clear"></div></div> </div></div><div class="grid_6"><div class="ds_blue_border marTop26 equalbottom"><div class="datasheet-ads-container" ><a href="/products/mfluor-violet-fluorescent-conjugated-antibodies" target="_parent"><img loading="lazy" src="https://images.novusbio.com/design/mfluor-violet-conjugated-antibodies-banner-final-v5-349x119.jpg" alt="mFluor Violet Conjugated Antibodies" title="mFluor Violet Conjugated Antibodies" class="datasheet-adzone" loading="lazy"></a></div><a id="jump_distributor"></a> <h2 class="greyHead2">Contact Information</h2> <div class="ds_info"> <div id="distributors"></div> </div> <div id="et_reload_trigger" style="display:none;">reload</div><h2 class="greyHead2">Product PDFs</h2><div class="silverHeadShort"> <span class="file"><a href="//aero.bio-techne.com/sds/pdf/mab1259" target="_blank" class="sprite_dsPDF"><span class="pdfSmaller"> </span></a></span> <span class="download-file-text" ><a href="//aero.bio-techne.com/sds/pdf/mab1259" target="_blank" class="datasheet-download sdsFile">PDF SDS</a></span> </div><div class="silverHeadShort"> <span class="file"><a href="//resources.rndsystems.com/pdfs/datasheets/mab1259.pdf" target="_blank" class="sprite_dsPDF"><span class="pdfSmaller"> </span></a></span> <span class="download-file-text" ><a href="//resources.rndsystems.com/pdfs/datasheets/mab1259.pdf" target="_blank" class="datasheet-download">PDF Datasheet</a></span> </div><div class="silverHeadShort"> <span class="file"><a href="mailto:novus@novusbio.com?subject=Request%20CofA%20for%20MAB1259" class="sprite_newDocument"><span class="downloadBlank"> </span></a></span> <span class="download-file-text"><a href="mailto:nb-technical@bio-techne.com?subject=Request%20CofA%20for%20MAB1259&body=Specific%20catalog%20number(if multiple sizes):%0ALot%20Number:%0AAny%20additional%20products:">Request CofA</a></span> </div><h2 class="greyHead2">Calculators</h2> <div class="calc_wrapper"> <div class="dsSprite_calc"></div> <div class="fake_link" id="calc_reconstitution_link">Concentration Calculator</div> <div id="calc_reconstitution_wrapper" class="calc_function_wrapper"> <div class="calc_popup"> <div class="calc_close"> <div class="dsSprite_calc_close"></div> </div> <div class="calc_header">Concentration Calculator</div> <div id="reconstitution_calculator" class="calculator"> <div class="reconstitution_calculator_text" id="reconstitution_calculator_instructions"> <p>The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.</p> </div> <div class="calc_section"> <label for="reconstitution_calculator_volume" class="calculator_label">Volume</label> <input id="reconstitution_calculator_volume" name="reconstitution_calculator_volume" type="text" maxlength="16" placeholder="volume" class="calculator_input calculator_text"/> <select id="reconstitution_calculator_volume_unit" class="calculator_input calculator_select"> <option value="ml">ml</option> <option value="ul" selected="selected">ul</option> </select> </div> <span class="calculator_equals calculator_operator">=</span> <div class="calc_section"> <label for="reconstitution_calculator_mass" class="calculator_label">Mass</label> <input id="reconstitution_calculator_mass" name="reconstitution_calculator_mass" type="text" maxlength="16" placeholder="mass" class="calculator_input calculator_text"/> <select id="reconstitution_calculator_mass_unit" 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</div> </div> <h2 class="greyHead2">Recent Reviews</h2><div class="review_summary"> <div class="review_summary_left"> <div class="review_large_number">4.3</div> <div class="dsSprite_stars4"></div> </div> <div class="review_summary_right"> <table> <tbody><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">5</div></td><td style="position:relative;width:155px;"><div class="review_bar star5" style="width:50%;"></div><div class="review_bar_value">1</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">4</div></td><td style="position:relative;width:155px;"><div class="review_bar star4" style="width:100%;"></div><div class="review_bar_value">2</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">3</div></td><td style="position:relative;width:155px;"><div class="review_bar star3" style="width:0%;"></div><div class="review_bar_value">0</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">2</div></td><td style="position:relative;width:155px;"><div class="review_bar star2" style="width:0%;"></div><div class="review_bar_value">0</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">1</div></td><td style="position:relative;width:155px;"><div class="review_bar star1" style="width:0%;"></div><div class="review_bar_value">0</div></td></tr> </tbody> </table> </div> <hr /><div class="single_review"><div class="review_summary_image"><a href="//www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_58396_0_0.jpg" title="Human neural stem cells" class="colorbox" title="Immunocytochemistry" > <img loading="lazy" src="//www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_58396_0_0.jpg" class="reviews_imageBorder" width="75" alt="Immunocytochemistry Nestin MAB1259" /> <br/><span class="enlarge" href="#"><div class="dsSprite_magGlass"></div> Enlarge</span></a></div> <div class="review_summary_right"><table> <tbody> <tr> <td><div class="dsSprite_stars5" content="5"></div></td> <td>Verified Customer<br />02/10/2022</td> </tr> <tr> <td class="review_summary_title">Application: </td> <td>ICC<td> </tr> <tr> <td class="review_summary_title">Species: </td> <td>Human</td> </tr> </tbody> </table> <div class="text_right" style="margin-bottom:-8px;"><a href="#ReviewsSection">read this review</a></div></div></div> <hr /><div class="single_review"><div class="review_summary_image"><a href="//www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_46716_0_0_0.png" title="Glioblastoma multiforme stained with anti-nestin antibody 1:100" class="colorbox" title="Other" > <img loading="lazy" src="//www.novusbio.com/sites/novusbio.com/files/reviews/review_mab1259_46716_0_0_0.png" class="reviews_imageBorder" width="75" alt="Other Nestin MAB1259" /> <br/><span class="enlarge" href="#"><div class="dsSprite_magGlass"></div> Enlarge</span></a></div> <div class="review_summary_right"><table> <tbody> <tr> <td><div class="dsSprite_stars4" content="4"></div></td> <td>Verified Customer<br />03/09/2019</td> </tr> <tr> <td class="review_summary_title">Application: </td> <td>Immunofluorescence - paraffin<td> </tr> <tr> <td class="review_summary_title">Species: </td> <td>Human</td> </tr> </tbody> </table> <div class="text_right" style="margin-bottom:-8px;"><a href="#ReviewsSection">read this review</a></div></div></div> <hr /><div class="single_review"><div class="review_summary_image"> </div> <div class="review_summary_right"><table> <tbody> <tr> <td><div class="dsSprite_stars4" content="4"></div></td> <td>Verified Customer<br />02/04/2015</td> </tr> <tr> <td class="review_summary_title">Application: </td> <td>IF<td> </tr> <tr> <td class="review_summary_title">Species: </td> <td>Human</td> </tr> </tbody> </table> <div class="text_right" style="margin-bottom:-8px;"><a href="#ReviewsSection">read this review</a></div></div></div> <hr /><div class="align-right" style="margin-right:10px;"> <a href="#ReviewsSection"> <button class="greybutton btn_width">read all the reviews</button> </a> </div> </div><h2 class="greyHead2">Bioinformatics</h2> <div class="ds_info"> <a id="tab1bioinformatics"></a> <div> <table class="ds_list_right wide top"> <tr class="lined"> <td><strong>Gene Symbol</strong></td> <td><a href="/gene-name/NES">NES</a></td> </tr></table> </div> </div> </div> </div><div class="clear"></div><noscript><form autocomplete="off" action="/products/nestin-antibody-196908_mab1259" method="post" id="et-add-multiple-to-cart-form" accept-charset="UTF-8"><div><table class="sticky-enabled"> <thead><tr><th>Size</th><th>Price</th> </tr></thead> <tbody> <tr class="odd"><td><div class="atc_size" title="catalog # MAB1259-SP">25 ug</div><div data-msg='' class="atc_catnum">MAB1259-SP</div></td><td><div style="font-size:11px;"><a class="jump_distributor" href="#jump_distributor">Contact Your<br />Distributor</a></div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">8-10 Business Days</td> </tr> <tr class="odd"><td><div class="atc_size" title="catalog # MAB1259">100 ug</div><div data-msg='' class="atc_catnum">MAB1259</div></td><td><div style="font-size:11px;"><a class="jump_distributor" href="#jump_distributor">Contact Your<br />Distributor</a></div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">4-6 Business Days</td> </tr> </tbody> </table> <input type="hidden" name="form_build_id" value="form-BcNH-BHR0XK4iz3kKiBGfscVLC34SA9Thz6dsmftQUo" /> <input type="hidden" name="form_id" value="et_add_multiple_to_cart_form" /> </div></form></noscript> </div> </div> <div id="block-block-21" class="block block-block"> <div class="content">  <div class="embeddedServiceInvitation" id="snapins_invite" aria-live="assertive" role="dialog" aria-atomic="true" style="display: none;"> <div class="embeddedServiceInvitationHeader" aria-labelledby="snapins_titletext" 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Nestin Antibody (196908) [Unconjugated] (MAB1259): Novus Biologicals