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var(--bs-nav-link-padding-x);font-size:var(--bs-nav-link-font-size);font-weight:var(--bs-nav-link-font-weight);color:var(--bs-nav-link-color)}.nav-fill .nav-item{flex:1 1 auto;text-align:center}.nav-fill .nav-item .nav-link{width:100%}.navbar{--bs-navbar-padding-x:0;--bs-navbar-padding-y:0.5rem;--bs-navbar-color:rgba(0, 0, 0, 0.55);--bs-navbar-hover-color:rgba(0, 0, 0, 0.7);--bs-navbar-disabled-color:rgba(0, 0, 0, 0.3);--bs-navbar-active-color:rgba(0, 0, 0, 0.9);--bs-navbar-brand-padding-y:0.25rem;--bs-navbar-brand-margin-end:1rem;--bs-navbar-brand-font-size:1.25rem;--bs-navbar-brand-color:rgba(0, 0, 0, 0.9);--bs-navbar-brand-hover-color:rgba(0, 0, 0, 0.9);--bs-navbar-nav-link-padding-x:0.5rem;--bs-navbar-toggler-padding-y:0.25rem;--bs-navbar-toggler-padding-x:0.75rem;--bs-navbar-toggler-font-size:1.25rem;--bs-navbar-toggler-icon-bg:url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 30 30'%3e%3cpath stroke='rgba%280, 0, 0, 0.55%29' stroke-linecap='round' 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var(--bs-navbar-padding-x);background-image:var(--bs-gradient)}.navbar>.container,.navbar>.container-fluid{display:flex;flex-wrap:inherit;align-items:center;justify-content:space-between}.navbar-brand{padding-top:var(--bs-navbar-brand-padding-y);padding-bottom:var(--bs-navbar-brand-padding-y);margin-right:var(--bs-navbar-brand-margin-end);font-size:var(--bs-navbar-brand-font-size);color:var(--bs-navbar-brand-color);white-space:nowrap}.navbar-nav{--bs-nav-link-padding-x:0;--bs-nav-link-padding-y:0.7rem;--bs-nav-link-color:var(--bs-navbar-color);--bs-nav-link-hover-color:var(--bs-navbar-hover-color);--bs-nav-link-disabled-color:var(--bs-navbar-disabled-color);display:flex;flex-direction:column;padding-left:0;margin-bottom:0;list-style:none}.navbar-collapse{flex-basis:100%;flex-grow:1;align-items:center}.navbar-toggler{padding:var(--bs-navbar-toggler-padding-y) var(--bs-navbar-toggler-padding-x);font-size:var(--bs-navbar-toggler-font-size);line-height:1;color:var(--bs-navbar-color);background-color:transparent;border:var(--bs-border-width) solid var(--bs-navbar-toggler-border-color);border-radius:var(--bs-navbar-toggler-border-radius)}@media (min-width:576px){.navbar-expand-sm{flex-wrap:nowrap;justify-content:flex-start}.navbar-expand-sm .navbar-nav{flex-direction:row}.navbar-expand-sm .navbar-nav .nav-link{padding-right:var(--bs-navbar-nav-link-padding-x);padding-left:var(--bs-navbar-nav-link-padding-x)}.navbar-expand-sm .navbar-collapse{display:flex!important;flex-basis:auto}.navbar-expand-sm .navbar-toggler{display:none}}body:before{display:none}.navbar-dark{--bs-navbar-color:#324a98;--bs-navbar-hover-color:#4d4d4f;--bs-navbar-disabled-color:rgba(255, 255, 255, 0.25);--bs-navbar-active-color:#324a98;--bs-navbar-brand-color:#324a98;--bs-navbar-brand-hover-color:#324a98;--bs-navbar-toggler-border-color:transparent;--bs-navbar-toggler-icon-bg:none}.card{--bs-card-spacer-y:1rem;--bs-card-spacer-x:1rem;--bs-card-title-spacer-y:0.5rem;--bs-card-border-width:1px;--bs-card-border-color:var(--bs-border-color-translucent);--bs-card-border-radius:0.375rem;--bs-card-inner-border-radius:calc(0.375rem - 1px);--bs-card-cap-padding-y:0.5rem;--bs-card-cap-padding-x:1rem;--bs-card-cap-bg:rgba(0, 0, 0, 0.03);--bs-card-bg:#f8f9fa;--bs-card-img-overlay-padding:1rem;--bs-card-group-margin:0.75rem;position:relative;display:flex;flex-direction:column;min-width:0;height:var(--bs-card-height);word-wrap:break-word;background-color:var(--bs-card-bg);background-clip:border-box;border:var(--bs-card-border-width) solid var(--bs-card-border-color);border-radius:var(--bs-card-border-radius);box-shadow:var(--bs-card-box-shadow)}.card-body{flex:1 1 auto;padding:var(--bs-card-spacer-y) var(--bs-card-spacer-x);color:var(--bs-card-color)}.breadcrumb{display:flex;list-style:none;--bs-breadcrumb-padding-x:0;--bs-breadcrumb-padding-y:0.5rem;--bs-breadcrumb-margin-bottom:0;--bs-breadcrumb-font-size:0.75rem;--bs-breadcrumb-bg:transparent;--bs-breadcrumb-divider-color:#6c757d;--bs-breadcrumb-item-padding-x:0.5rem;--bs-breadcrumb-item-active-color:#6c757d;flex-wrap:wrap;padding:var(--bs-breadcrumb-padding-y) var(--bs-breadcrumb-padding-x);margin-bottom:var(--bs-breadcrumb-margin-bottom);font-size:var(--bs-breadcrumb-font-size);background-color:var(--bs-breadcrumb-bg);border-radius:var(--bs-breadcrumb-border-radius)}.breadcrumb-item+.breadcrumb-item{padding-left:var(--bs-breadcrumb-item-padding-x)}.breadcrumb-item+.breadcrumb-item::before{float:left;padding-right:var(--bs-breadcrumb-item-padding-x);color:var(--bs-breadcrumb-divider-color);content:var(--bs-breadcrumb-divider, "|")}.breadcrumb-item.active{color:var(--bs-breadcrumb-item-active-color)}.alert{--bs-alert-bg:transparent;--bs-alert-padding-x:1rem;--bs-alert-padding-y:1rem;--bs-alert-margin-bottom:1rem;--bs-alert-color:inherit;--bs-alert-border-color:transparent;--bs-alert-border:1px solid var(--bs-alert-border-color);--bs-alert-border-radius:0.375rem;position:relative;padding:var(--bs-alert-padding-y) var(--bs-alert-padding-x);margin-bottom:var(--bs-alert-margin-bottom);color:var(--bs-alert-color);background-color:var(--bs-alert-bg);border:var(--bs-alert-border);border-radius:var(--bs-alert-border-radius)}.alert-heading{color:inherit}.alert-link{font-weight:700}.alert-dismissible{padding-right:3rem}.alert-dismissible .btn-close{position:absolute;top:0;right:0;z-index:2;padding:1.25rem 1rem}.alert-primary,.alert-secondary{background-image:var(--bs-gradient)}.alert-primary{--bs-alert-color:rgb(30, 44.4, 91.2);--bs-alert-bg:rgb(214, 218.8, 234.4);--bs-alert-border-color:rgb(193.5, 200.7, 224.1)}.alert-primary .alert-link{color:#182449}.alert-secondary{--bs-alert-color:rgb(64.8, 70.2, 75);--bs-alert-bg:rgb(225.6, 227.4, 229);--bs-alert-border-color:rgb(210.9, 213.6, 216)}.alert-secondary .alert-link{color:#34383c}.alert-native,.alert-success,.alert-validation{--bs-alert-color:rgb(15, 81, 50.4);--bs-alert-bg:rgb(209, 231, 220.8);--bs-alert-border-color:rgb(186, 219, 203.7);background-image:var(--bs-gradient)}.alert-native .alert-link,.alert-success .alert-link,.alert-validation .alert-link{color:#0c4128}.alert-info,.alert-warning{background-image:var(--bs-gradient)}.alert-info{--bs-alert-color:rgb(5.2, 80.8, 96);--bs-alert-bg:rgb(206.6, 244.4, 252);--bs-alert-border-color:rgb(182.4, 239.1, 250.5)}.alert-info .alert-link{color:#04414d}.alert-warning{--bs-alert-color:rgb(102, 77.2, 2.8);--bs-alert-bg:rgb(255, 242.6, 205.4);--bs-alert-border-color:rgb(255, 236.4, 180.6)}.alert-warning .alert-link{color:#523e02}.alert-danger,.alert-error{--bs-alert-color:#8a0000;--bs-alert-bg:#facccc;--bs-alert-border-color:rgb(247.5, 178.5, 178.5);background-image:var(--bs-gradient)}.alert-danger .alert-link,.alert-error .alert-link{color:#6e0000}.alert-light{--bs-alert-color:rgb(99.2, 99.6, 100);--bs-alert-bg:rgb(253.6, 253.8, 254);--bs-alert-border-color:rgb(252.9, 253.2, 253.5);background-image:var(--bs-gradient)}.alert-light .alert-link{color:#4f5050}.alert-cleanup,.alert-dark{--bs-alert-color:rgb(19.8, 22.2, 24.6);--bs-alert-bg:rgb(210.6, 211.4, 212.2);--bs-alert-border-color:rgb(188.4, 189.6, 190.8);background-image:var(--bs-gradient)}.alert-cleanup .alert-link,.alert-dark .alert-link{color:#101214}.alert-inverse{--bs-alert-color:#666666;--bs-alert-bg:white;--bs-alert-border-color:white}.alert-inverse .alert-link{color:#525252}.alert-inverse,.alert-navbar,.alert-navitem{background-image:var(--bs-gradient)}.alert-navbar{--bs-alert-color:rgb(87.2, 88, 88.8);--bs-alert-bg:rgb(247.6, 248, 248.4);--bs-alert-border-color:rgb(243.9, 244.5, 245.1)}.alert-navbar .alert-link{color:#464647}.alert-navitem{--bs-alert-color:#666666;--bs-alert-bg:white;--bs-alert-border-color:white}.alert-navitem .alert-link{color:#525252}.alert-lightgray{--bs-alert-color:rgb(93.2, 94.4, 95.6);--bs-alert-bg:rgb(250.6, 251.2, 251.8);--bs-alert-border-color:rgb(248.4, 249.3, 250.2)}.alert-lightgray .alert-link{color:#4b4c4c}.alert-color-indigo,.alert-lightgray{background-image:var(--bs-gradient)}.alert-advertising,.alert-color-indigo{--bs-alert-color:rgb(61.2, 9.6, 145.2);--bs-alert-bg:rgb(224.4, 207.2, 252.4);--bs-alert-border-color:rgb(209.1, 183.3, 251.1)}.alert-color-indigo .alert-link{color:#310874}.alert-color-cyan{--bs-alert-color:rgb(5.2, 80.8, 96);--bs-alert-bg:rgb(206.6, 244.4, 252);--bs-alert-border-color:rgb(182.4, 239.1, 250.5);background-image:var(--bs-gradient)}.alert-color-cyan .alert-link{color:#04414d}.alert-color-blue,.alert-criticalcss{--bs-alert-color:rgb(7.8, 66, 151.8);--bs-alert-bg:rgb(206.6, 226, 254.6);--bs-alert-border-color:rgb(182.4, 211.5, 254.4);background-image:var(--bs-gradient)}.alert-color-blue .alert-link,.alert-criticalcss .alert-link{color:#063579}.alert-color-orange{background-image:var(--bs-gradient)}.alert-cache,.alert-color-orange{--bs-alert-color:rgb(151.8, 75.6, 12);--bs-alert-bg:rgb(254.6, 229.2, 208);--bs-alert-border-color:rgb(254.4, 216.3, 184.5)}.alert-color-orange .alert-link{color:#793c0a}.alert-color-red{--bs-alert-color:rgb(132, 31.8, 41.4);--bs-alert-bg:rgb(248, 214.6, 217.8);--bs-alert-border-color:rgb(244.5, 194.4, 199.2);background-image:var(--bs-gradient)}.alert-color-red .alert-link{color:#6a1921}.alert-cdnjs,.alert-color-yellow{--bs-alert-color:rgb(102, 77.2, 2.8);--bs-alert-bg:rgb(255, 242.6, 205.4);--bs-alert-border-color:rgb(255, 236.4, 180.6)}.alert-cdnjs .alert-link,.alert-color-yellow .alert-link{color:#523e02}.alert-cdnjs,.alert-color-teal,.alert-color-yellow{background-image:var(--bs-gradient)}.alert-color-teal,.alert-topic{--bs-alert-color:rgb(19.2, 120.6, 90.6);--bs-alert-bg:rgb(210.4, 244.2, 234.2);--bs-alert-border-color:rgb(188.1, 238.8, 223.8)}.alert-color-teal .alert-link{color:#0f6048}.alert-color-green{--bs-alert-color:rgb(15, 81, 50.4);--bs-alert-bg:rgb(209, 231, 220.8);--bs-alert-border-color:rgb(186, 219, 203.7);background-image:var(--bs-gradient)}.alert-color-green .alert-link{color:#0c4128}.alert-cloudinary,.alert-color-pink{--bs-alert-color:rgb(128.4, 30.6, 79.2);--bs-alert-bg:rgb(246.8, 214.2, 230.4);--bs-alert-border-color:rgb(242.7, 193.8, 218.1);background-image:var(--bs-gradient)}.alert-cloudinary .alert-link,.alert-color-pink .alert-link{color:#67183f}.alert-color-black{--bs-alert-color:black;--bs-alert-bg:#cccccc;--bs-alert-border-color:rgb(178.5, 178.5, 178.5);background-image:var(--bs-gradient)}.alert-color-black .alert-link{color:#000}.alert-color-white{--bs-alert-color:#666666;--bs-alert-bg:white;--bs-alert-border-color:white;background-image:var(--bs-gradient)}.alert-color-white .alert-link{color:#525252}.alert-color-gray{--bs-alert-color:rgb(64.8, 70.2, 75);--bs-alert-bg:rgb(225.6, 227.4, 229);--bs-alert-border-color:rgb(210.9, 213.6, 216);background-image:var(--bs-gradient)}.alert-color-gray .alert-link{color:#34383c}.alert-color-gray-dark{--bs-alert-color:rgb(31.2, 34.8, 38.4);--bs-alert-bg:rgb(214.4, 215.6, 216.8);--bs-alert-border-color:rgb(194.1, 195.9, 197.7);background-image:var(--bs-gradient)}.alert-color-gray-dark .alert-link{color:#191c1f}.alert-cache{--bs-alert-color:rgb(61.2, 9.6, 145.2);--bs-alert-bg:rgb(224.4, 207.2, 252.4);--bs-alert-border-color:rgb(209.1, 183.3, 251.1);background-image:var(--bs-gradient)}.alert-cache .alert-link{color:#310874}.alert-notice{--bs-alert-color:rgb(5.2, 80.8, 96);--bs-alert-bg:rgb(206.6, 244.4, 252);--bs-alert-border-color:rgb(182.4, 239.1, 250.5)}.alert-notice .alert-link{color:#04414d}.alert-advertising,.alert-notice,.alert-topic{background-image:var(--bs-gradient)}.alert-topic{--bs-alert-color:rgb(113.4, 34.2, 10.2);--bs-alert-bg:rgb(241.8, 215.4, 207.4);--bs-alert-border-color:rgb(235.2, 195.6, 183.6)}.alert-topic .alert-link{color:#5b1b08}.alert-advertising{--bs-alert-color:rgb(102, 77.2, 2.8);--bs-alert-bg:rgb(255, 242.6, 205.4);--bs-alert-border-color:rgb(255, 236.4, 180.6)}.alert-advertising .alert-link{color:#523e02}.list-group{--bs-list-group-color:#212529;--bs-list-group-bg:#fff;--bs-list-group-border-color:rgba(0, 0, 0, 0.125);--bs-list-group-border-width:1px;--bs-list-group-border-radius:0.375rem;--bs-list-group-item-padding-x:1rem;--bs-list-group-item-padding-y:0.5rem;--bs-list-group-action-color:#495057;--bs-list-group-action-hover-color:#495057;--bs-list-group-action-hover-bg:#f8f9fa;--bs-list-group-action-active-color:#212529;--bs-list-group-action-active-bg:#e9ecef;--bs-list-group-disabled-color:#6c757d;--bs-list-group-disabled-bg:#fff;--bs-list-group-active-color:#fff;--bs-list-group-active-bg:#bd3911;--bs-list-group-active-border-color:#bd3911;display:flex;flex-direction:column;padding-left:0;margin-bottom:0;border-radius:var(--bs-list-group-border-radius)}.list-group-item{position:relative;display:block;padding:var(--bs-list-group-item-padding-y) var(--bs-list-group-item-padding-x);color:var(--bs-list-group-color);background-color:var(--bs-list-group-bg);border:var(--bs-list-group-border-width) solid var(--bs-list-group-border-color)}.list-group-item:first-child{border-top-left-radius:inherit;border-top-right-radius:inherit}.list-group-item:last-child{border-bottom-right-radius:inherit;border-bottom-left-radius:inherit}.list-group-item+.list-group-item{border-top-width:0}.btn-close{box-sizing:content-box;width:1em;height:1em;padding:.25em;color:#000;background:url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%23000'%3e%3cpath d='M.293.293a1 1 0 0 1 1.414 0L8 6.586 14.293.293a1 1 0 1 1 1.414 1.414L9.414 8l6.293 6.293a1 1 0 0 1-1.414 1.414L8 9.414l-6.293 6.293a1 1 0 0 1-1.414-1.414L6.586 8 .293 1.707a1 1 0 0 1 0-1.414z'/%3e%3c/svg%3e") center/1em auto no-repeat;border:0;border-radius:.375rem;opacity:.5}.modal{--bs-modal-zindex:1055;--bs-modal-width:500px;--bs-modal-padding:1rem;--bs-modal-margin:0.5rem;--bs-modal-bg:#fff;--bs-modal-border-color:var(--bs-border-color-translucent);--bs-modal-border-width:1px;--bs-modal-border-radius:0.5rem;--bs-modal-box-shadow:0 0.125rem 0.25rem rgba(0, 0, 0, 0.075);--bs-modal-inner-border-radius:calc(0.5rem - 1px);--bs-modal-header-padding-x:1rem;--bs-modal-header-padding-y:1rem;--bs-modal-header-padding:1rem 1rem;--bs-modal-header-border-color:var(--bs-border-color);--bs-modal-header-border-width:1px;--bs-modal-title-line-height:1.5;--bs-modal-footer-gap:0.5rem;--bs-modal-footer-border-color:var(--bs-border-color);--bs-modal-footer-border-width:1px;position:fixed;top:0;left:0;z-index:var(--bs-modal-zindex);display:none;width:100%;height:100%;overflow-x:hidden;overflow-y:auto;outline:0}.modal-dialog{position:relative;width:auto;margin:var(--bs-modal-margin)}.modal.fade .modal-dialog{transform:translate(0,-50px)}.modal-content{position:relative;display:flex;flex-direction:column;width:100%;color:var(--bs-modal-color);background-color:var(--bs-modal-bg);background-clip:padding-box;border:var(--bs-modal-border-width) solid var(--bs-modal-border-color);border-radius:var(--bs-modal-border-radius);box-shadow:var(--bs-modal-box-shadow);outline:0}.modal-header{display:flex;flex-shrink:0;align-items:center;justify-content:space-between;padding:var(--bs-modal-header-padding);border-bottom:var(--bs-modal-header-border-width) solid var(--bs-modal-header-border-color);border-top-left-radius:var(--bs-modal-inner-border-radius);border-top-right-radius:var(--bs-modal-inner-border-radius)}.modal-title{margin-bottom:0;line-height:var(--bs-modal-title-line-height)}.modal-body{position:relative;flex:1 1 auto;padding:var(--bs-modal-padding)}@media (min-width:576px){.modal{--bs-modal-margin:1.75rem;--bs-modal-box-shadow:0 0.5rem 1rem rgba(0, 0, 0, 0.15)}.modal-dialog{max-width:var(--bs-modal-width);margin-right:auto;margin-left:auto}.modal-sm{--bs-modal-width:300px}}.offcanvas{--bs-offcanvas-zindex:1045;--bs-offcanvas-width:400px;--bs-offcanvas-height:30vh;--bs-offcanvas-padding-x:1rem;--bs-offcanvas-padding-y:1rem;--bs-offcanvas-bg:#fff;--bs-offcanvas-border-width:1px;--bs-offcanvas-border-color:var(--bs-border-color-translucent);--bs-offcanvas-box-shadow:0 0.125rem 0.25rem rgba(0, 0, 0, 0.075);position:fixed;bottom:0;z-index:var(--bs-offcanvas-zindex);display:flex;flex-direction:column;max-width:100%;color:var(--bs-offcanvas-color);visibility:hidden;background-color:var(--bs-offcanvas-bg);background-clip:padding-box;outline:0;box-shadow:var(--bs-offcanvas-box-shadow)}.offcanvas.offcanvas-start{top:0;left:0;width:var(--bs-offcanvas-width);border-right:var(--bs-offcanvas-border-width) solid 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fa-comment-alt fa-lg"></i> </a></li></ul> </aside><div class="article-body col-md-11 col-12"><span itemprop="author" itemscope itemtype="https://schema.org/Person"> <meta itemprop="name" content="Tech Briefs"> </span><a id="startOfPage"></a> <h4>The cUSP of Cavitation-Enhanced Transdermal Drug Delivery</h4> <p><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1691973155/sites/mdb/articles/2023/features/MDB-0823-p4-fig1.jpg' class=' w-100 cld-responsive' alt='' /></p> <p>In hopes of making it easier to deliver drugs through the skin, MIT researchers have developed a wearable patch that applies painless ultrasonic waves to the skin, creating tiny channels that drugs can pass through. The approach could lend itself to delivery of treatments for a variety of skin conditions. It could also be adapted to deliver hormones, muscle relaxants, and other drugs.</p> <p> <a href="/tv/cusp" rel="noopener noreferrer">https://www.medicaldesignbriefs.com/tv/cusp</a></p> <hr /> <h4>Biodegradable Millirobot Releases Targeted Drugs</h4> <p><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1691973155/sites/mdb/articles/2023/features/MDB-0823-p4-fig2.jpg' class=' w-100 cld-responsive' alt='' /></p> <p>Millirobots have the potential for controlled release of drugs in targeted positions in the intestines. Research has shed light on the development of millirobots, with the potential application of the controlled release of drugs in targeted positions in the intestines. Research has also facilitated the development of biodegradable and adaptive devices with biomedical applications.</p> <p> <a href="/tv/millirobot" rel="noopener noreferrer">https://www.medicaldesignbriefs.com/tv/millirobot</a></p> <hr /> <h4>Compound Reverses Effects of Potentially Deadly Drugs</h4><div class="ad-position g-0 row mb-3 "> <div class="col-12 align-content-center mx-auto"> <script tb-donotmove>window.ntb_google_ad_manager_items=window.ntb_google_ad_manager_items||[];ntb_google_ad_manager_items.push({display_sizes:['xs','sm'],slot_ad_unit:'medicaldesignbriefs.com_450x450_300x300',slot_code:'21835072403',slot:'/21835072403/medicaldesignbriefs.com_450x450_300x300',slot_ad_sizes:['fluid',[450,450],[300,300]],div_id:'GAM_pos_22_modid_421',target_pos:'22',size_mapping:[],slot_ad_empty:'default'});</script> <div id='GAM_pos_22_modid_421' class=""></div></div></div><p><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1691973155/sites/mdb/articles/2023/features/MDB-0823-p4-fig3.jpg' class=' w-100 cld-responsive' alt='' /></p> <p>Drug overdoses in the United States have risen sharply in the last two decades. To identify a more universal treatment for drug overdose, a team of scientists tested a chemical compound as an antidote for methamphetamine and fentanyl. Scientists tested a chemical compound — Pillar[6]MaxQ (P6AS) — as an antidote.</p> <p> <a href="/tv/compound-reverses" rel="noopener noreferrer">https://www.medicaldesignbriefs.com/tv/compound-reverses</a></p> <hr /> <h4>Rational Design of Drug-Delivery Systems</h4> <p><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1691973155/sites/mdb/articles/2023/features/MDB-0823-p4-fig4.jpg' class=' w-100 cld-responsive' alt='' /></p> <p>Many drugs must overcome biological barriers and find their way to diseased tissues to be therapeutically effective. A new technology uses a natural ligand called gambogic acid that avoids competition from the body’s owned ligand called transferrin when binding to the target CD 71 cell surface transfer and receptor.</p> <p> <a href="/tv/rational-design" rel="noopener noreferrer">https://www.medicaldesignbriefs.com/tv/rational-design</a></p> <hr> <div class="ntb_tagsbot"> <div class="taglist"> <strong class="sans-serif text-small">Topics:</strong><br> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/medical/drug_delivery/mdb/*?start=0"> <i class="fa-duotone fa-book-medical"></i> Drug Delivery</a> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/markets/drug_delivery/mdb/*?start=0"> <i class="fa-duotone fa-people-group"></i> Drug Delivery</a> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/medical/medical/mdb/*?start=0"> <i class="fa-duotone fa-book-medical"></i> Medical</a> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/robotics_automation_control/robotics/mdb/*?start=0"> <i class="fa-duotone fa-conveyor-belt-boxes"></i> Robotics</a> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/wearables/wearables/mdb/*?start=0"> <i class="fa-duotone fa-watch-smart"></i> Wearables</a></div></div> <div class="related-content"> <hr> <h4>More From SAE Media Group</h4> <div class="row row-cols-1 row-cols-lg-2 g-1"> <div class="col "> <div class="card text-dark border-primary border-start-0 border-bottom-0 border-end-0 rounded-0 h-100"> <div class="row g-0"> <div class="col-9 col-lg-8"> <div class="card-body p-1 pb-0"> <h6 class="tb-topic-overline text-muted text-uppercase" style="font-size:0.7rem">Tech Briefs</h6> <div 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