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(PDF) Hepatitis B component does not interfere with the immune response to diphtheria, tetanus and whole-cell Bordetella pertussis components of a quadrivalent (DTPw- … | JUAN LOPEZ - Academia.edu
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{"work":{"id":12232174,"created_at":"2015-05-04T13:47:01.575-07:00","from_world_paper_id":135965403,"updated_at":"2024-11-17T19:53:35.640-08:00","_data":{"publisher":"Elsevier","grobid_abstract":"The aim of this single-blind, parallel trial was to assess whether the hepatitis B (HB) component of a DTPw-HB vaccine inter$eres with the immune response to the other three components when administered at 3, 5 and 7 months of age. 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/><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Hepatitis B component does not interfere with the immune response to diphtheria, tetanus and whole-cell Bordetella pertussis components of a quadrivalent (DTPw- …</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="30716972" href="https://unearte.academia.edu/JUANLOPEZ"><img alt="Profile image of JUAN LOPEZ" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />JUAN LOPEZ</a></div><p class="ds-work-card--detail ds2-5-body-sm">1997, Vaccine</p><div 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data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="46291457" data-landing_url="https://www.academia.edu/12232174/Hepatitis_B_component_does_not_interfere_with_the_immune_response_to_diphtheria_tetanus_and_whole_cell_Bordetella_pertussis_components_of_a_quadrivalent_DTPw_" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="11441050" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/11441050/Hepatitis_B_component_does_not_interfere_with_the_immune_response_to_diphtheria_tetanus_and_whole_cell_Bordetella_pertussis_components_of_a_quadrivalent_DTPw_HB_vaccine_a_controlled_trial_in_healthy_infants">Hepatitis B component does not interfere with the immune response to diphtheria, tetanus and whole-cell Bordetella pertussis components of a quadrivalent (DTPw-HB) vaccine: a controlled trial in healthy infants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="27850479" href="https://independent.academia.edu/JuanLopez251">Juan Lopez</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 1997</p><p class="ds-related-work--abstract ds2-5-body-sm">The aim of this single-blind, parallel trial was to assess whether the hepatitis B (HB) component of a DTPw-HB vaccine interferes with the immune response to the other three components when administered at 3, 5 and 7 months of age. One hundred and six infants were randomized to receive three doses of DTPw or DTPw-HB vaccines. Seroprotection (or seroresponse) rates and geometric mean titers (GMT) of antibodies were assessed 3–6 weeks after the third dose. Anti-diphtheria, anti-tetanus and anti-Bordetella pertussis antibodies were measured by ELISA and anti-HBs by radio-immunoassay. Local and general signs and symptoms were recorded for a 4-day follow-up period after each vaccination. After the full vaccination course all subjects in both groups had seroprotective titers (≥0.1 IU ml−1) against diphtheria and tetanus and seroresponded (titers ≥15 EL.U ml−1) to B. pertussis, and there was no significant difference between groups in relation to GMT. All subjects vaccinated with DTPw-HB had seroprotective levels (≥10 mIU ml−1) of anti-HBs antibodies after the third dose (GMT of 2318 mIU ml−1). Overall there were no significant differences between groups in relation to the incidence of local and general symptoms. 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class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="59825166" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/59825166/Effect_of_tetanus_diphtheria_vaccine_on_immune_response_to_Hepatitis_b_vaccine_in_low_responder_individuals">Effect of tetanus-diphtheria vaccine on immune response to Hepatitis b vaccine in low-responder individuals</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="59494479" href="https://independent.academia.edu/AbbasHaghighat">Abbas Haghighat</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Preventive Medicine, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Effect of tetanus-diphtheria vaccine on immune response to Hepatitis b vaccine in low-responder individuals","attachmentId":73547573,"attachmentType":"pdf","work_url":"https://www.academia.edu/59825166/Effect_of_tetanus_diphtheria_vaccine_on_immune_response_to_Hepatitis_b_vaccine_in_low_responder_individuals","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/59825166/Effect_of_tetanus_diphtheria_vaccine_on_immune_response_to_Hepatitis_b_vaccine_in_low_responder_individuals"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="13904521" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/13904521/Immunogenicity_and_Reactogenicity_following_Primary_Immunisation_with_a_Combined_DTaP_HBV_Vaccine_and_a_Haemophilus_influenzae_Type_B_Vaccine_Administered_by_Separate_or_Mixed_Injection">Immunogenicity and Reactogenicity following Primary Immunisation with a Combined DTaP-HBV Vaccine and a??Haemophilus influenzae Type B Vaccine Administered by Separate or Mixed Injection</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32975976" href="https://ulg.academia.edu/KarinHardt">Karin Hardt</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Drug Investigation, 2005</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Immunogenicity and Reactogenicity following Primary Immunisation with a Combined DTaP-HBV Vaccine and a??Haemophilus influenzae Type B Vaccine Administered by Separate or Mixed Injection","attachmentId":44817726,"attachmentType":"pdf","work_url":"https://www.academia.edu/13904521/Immunogenicity_and_Reactogenicity_following_Primary_Immunisation_with_a_Combined_DTaP_HBV_Vaccine_and_a_Haemophilus_influenzae_Type_B_Vaccine_Administered_by_Separate_or_Mixed_Injection","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/13904521/Immunogenicity_and_Reactogenicity_following_Primary_Immunisation_with_a_Combined_DTaP_HBV_Vaccine_and_a_Haemophilus_influenzae_Type_B_Vaccine_Administered_by_Separate_or_Mixed_Injection"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="109548111" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/109548111/Immunogenicity_of_recombinant_hepatitis_B_vaccine_comparison_of_two_different_vaccination_schedules">Immunogenicity of recombinant hepatitis B vaccine: comparison of two different vaccination schedules</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="42060083" href="https://gazi.academia.edu/Ay%C5%9Feg%C3%BClAtakY%C3%BCcel">Ayşegül Atak Yücel</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Infection, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Immunogenicity of recombinant hepatitis B vaccine: comparison of two different vaccination schedules","attachmentId":107640266,"attachmentType":"pdf","work_url":"https://www.academia.edu/109548111/Immunogenicity_of_recombinant_hepatitis_B_vaccine_comparison_of_two_different_vaccination_schedules","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/109548111/Immunogenicity_of_recombinant_hepatitis_B_vaccine_comparison_of_two_different_vaccination_schedules"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="22865861" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/22865861/Immunological_response_to_two_hepatitis_B_vaccines_administered_in_two_different_schedules">Immunological response to two hepatitis B vaccines administered in two different schedules</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="44525090" href="https://independent.academia.edu/GitaNataraj">Gita Nataraj</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Indian Journal of Pediatrics</p><p class="ds-related-work--abstract ds2-5-body-sm">To evaluate the antibody response to a plasma derived hepatitis B vaccine containing pre-S and S antigens and a recombinant vaccine containing only S antigen and compare the two vaccines in 0, 1, 2 and 0, 1, 6, schedules One hundred fifty nine healthy infants were randomized to receive the vaccines in two different schedules. Anti HBs titers were estimated prior to the vaccination and then one-month following the second and third doses. Both the vaccines produced a high rate of seroconversion and seroprotection. The antibody response was similar with both the vaccines and the 0, 1, 6, schedule induced a significantly higher antibody level than the 0, 1, 2, schedule. 0, 1, 6 schedule produces a higher antibody level than 0, 1, 2 schedule though both the schedules have good seroconversion and seroprotection rates with both the vaccines.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Immunological response to two hepatitis B vaccines administered in two different schedules","attachmentId":43406232,"attachmentType":"pdf","work_url":"https://www.academia.edu/22865861/Immunological_response_to_two_hepatitis_B_vaccines_administered_in_two_different_schedules","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/22865861/Immunological_response_to_two_hepatitis_B_vaccines_administered_in_two_different_schedules"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":46291457,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":46291457,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_46291457" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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href="https://www.academia.edu/4278383/Primary_vaccination_of_infants_with_diphtheria_tetanus_acellular_pertussis_hepatitis_B_virus_inactivated_polio_virus_and_Haemophilus_influenzae_type_b_vaccines_given_as_either_separate_or_mixed_injections"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="5" data-entity-id="28870297" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/28870297/Quality_of_the_Haemophilus_influenzae_Type_b_Hib_Antibody_Response_Induced_by_Diphtheria_Tetanus_Acellular_Pertussis_Hib_Combination_Vaccines">Quality of the Haemophilus influenzae Type b (Hib) Antibody Response Induced by Diphtheria-Tetanus-Acellular Pertussis/Hib Combination Vaccines</a><div 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href="https://www.academia.edu/54679371/Immunogenicity_of_three_recombinant_hepatitis_B_vaccines_administered_to_students_in_three_doses_containing_half_the_antigen_amount_routinely_used_for_adult_vaccination">Immunogenicity of three recombinant hepatitis B vaccines administered to students in three doses containing half the antigen amount routinely used for adult vaccination</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="88361944" href="https://independent.academia.edu/Jos%C3%A9Lu%C3%ADsDaSilveiraBaldy">José Luís Da Silveira Baldy</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Revista do Instituto de Medicina Tropical de São Paulo, 2004</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Immunogenicity of three recombinant hepatitis B vaccines 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class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="26641596" href="https://independent.academia.edu/EugeniodeFrutos">Eugenio de Frutos</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36236693" href="https://independent.academia.edu/JosepMar%C3%A9s">Josep Marés</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vaccine, 2003</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Comparison of the reactogenicity and immunogenicity of a combined diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated polio (DTPa–HBV–IPV) vaccine, mixed with the Haemophilus influenzae type b (Hib) conjugate vaccine and administered as a single injection, with the DTPa–IPV/Hib 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href="https://www.academia.edu/16795810/Comparison_of_the_reactogenicity_and_immunogenicity_of_a_combined_diphtheria_tetanus_acellular_pertussis_hepatitis_B_inactivated_polio_DTPa_HBV_IPV_vaccine_mixed_with_the_Haemophilus_influenzae_type_b_Hib_conjugate_vaccine_and_administered_as_a_single_injection_with_the_DTPa_IPV_Hib_and_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="8" data-entity-id="92826712" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/92826712/Reactogenicity_and_Immunogenicity_Profiles_of_a_Novel_Pentavalent_Diphtheria_Tetanus_Whole_Cell_Pertussis_Hepatitis_B_and_Haemophilus_Influenzae_Type_B_Vaccine">Reactogenicity and Immunogenicity Profiles of a Novel Pentavalent Diphtheria-Tetanus???Whole Cell Pertussis???Hepatitis B and Haemophilus Influenzae Type B Vaccine</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="249836346" href="https://independent.academia.edu/TheinAungMyat">Aung Myat Thein</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Pediatric Infectious Disease Journal, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Reactogenicity and Immunogenicity Profiles of a Novel Pentavalent Diphtheria-Tetanus???Whole Cell Pertussis???Hepatitis B and Haemophilus Influenzae Type B 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data-collection-position="9" data-entity-id="120255181" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/120255181/Simultaneous_administration_of_diphtheria_tetanus_pertussis_polio_and_hepatitis_B_vaccines_in_a_simplified_immunization_program_immune_response_to_diphtheria_toxoid_tetanus_toxoid_pertussis_and_hepatitis_B_surface_antigen">Simultaneous administration of diphtheria-tetanus-pertussis-polio and hepatitis B vaccines in a simplified immunization program: immune response to diphtheria toxoid, tetanus toxoid, pertussis, and hepatitis B surface antigen</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="74108320" href="https://independent.academia.edu/PierreCoursaget">Pierre Coursaget</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Infection and Immunity, 1986</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Simultaneous administration of diphtheria-tetanus-pertussis-polio and hepatitis B vaccines in a simplified immunization program: immune response to diphtheria toxoid, tetanus toxoid, pertussis, and hepatitis B surface antigen","attachmentId":115466054,"attachmentType":"pdf","work_url":"https://www.academia.edu/120255181/Simultaneous_administration_of_diphtheria_tetanus_pertussis_polio_and_hepatitis_B_vaccines_in_a_simplified_immunization_program_immune_response_to_diphtheria_toxoid_tetanus_toxoid_pertussis_and_hepatitis_B_surface_antigen","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline 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Healthy Infants</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32949940" href="https://cuni.academia.edu/RomanPrymula">Roman Prymula</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33007297" href="https://independent.academia.edu/M%C3%A1riaStefkovicov%C3%A1">Mária Stefkovicová</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Human Vaccines, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The Immunogenicity and Reactogenicity of a New DTPw-HBV Vaccine as a Primary and Booster Vaccination Dourse in Healthy 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data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/44640632/Immune_response_to_hepatitis_B_vaccine_in_a_group_of_vaccinees_in_the_Faculty_of_Allied_Health_Sciences_of_the_University_of_Peradeniya">Immune response to hepatitis B vaccine in a group of vaccinees in the Faculty of Allied Health Sciences of the University of Peradeniya</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="180696973" href="https://independent.academia.edu/FaseehaNoordeen">Faseeha Noordeen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Sri Lankan Journal of Infectious Diseases, 2015</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Immune response to hepatitis B vaccine in a 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js-related-work-sidebar-card" data-collection-position="12" data-entity-id="120255205" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/120255205/Clinical_trial_of_hepatitis_B_vaccine_in_a_simplified_immunization_programme">Clinical trial of hepatitis B vaccine in a simplified immunization programme</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="74108320" href="https://independent.academia.edu/PierreCoursaget">Pierre Coursaget</a></div><p class="ds-related-work--metadata ds2-5-body-xs">PubMed, 1986</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Clinical trial of hepatitis B vaccine in a simplified immunization 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href="https://www.academia.edu/81649336/Pattern_of_functional_antibody_activity_against_Haemophilus_influenzae_type_b_Hib_in_infants_immunized_with_diphtheria_tetanus_pertussis_Hib_Brazilian_combination_vaccine">Pattern of functional antibody activity against Haemophilus influenzae type b (Hib) in infants immunized with diphtheria-tetanus-pertussis/Hib Brazilian combination vaccine</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="223806153" href="https://independent.academia.edu/DeniseCristinaMatos">Denise Cristina Matos</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Brazilian Journal of Medical and Biological Research, 2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Pattern of functional antibody activity against Haemophilus influenzae 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ds2-5-body-xs">Vaccine, 2001</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Reactogenicity of DTPa-HBV/Hib vaccine administered as a single injection vs DTPa-HBV and Hib vaccines administered simultaneously at separate sites, to infants at 2, 4 and 6 months of age","attachmentId":43111726,"attachmentType":"pdf","work_url":"https://www.academia.edu/15536449/Reactogenicity_of_DTPa_HBV_Hib_vaccine_administered_as_a_single_injection_vs_DTPa_HBV_and_Hib_vaccines_administered_simultaneously_at_separate_sites_to_infants_at_2_4_and_6_months_of_age","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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