Single Cell Sequencing | GENEWIZ from Azenta

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Whole Genome Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/Regulatory' style='color:#585F69;font-size:14px'>GLP-Compliant Overview</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-Confirmatory-Sequencing' style='color:#585F69;font-size:14px'>GLP Confirmatory Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-SNP-Mutation-Analysis' style='color:#585F69;font-size:14px'>GLP SNP Mutation Analysis</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-Plasmid-Prep' style='color:#585F69;font-size:14px'>GLP Plasmid Prep</a></li><li><a href='/en/Public/Services/Clinical-Services/Nucleic-Acid-Extraction' style='color:#585F69;font-size:14px'>GLP Nucleic Acid Extraction</a></li><li><a href='/en/Public/Services/Clinical-Services/Biofluid-Processing-Overview' style='color:#585F69;font-size:14px'>Biofluid Processing</a></li><li><a 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} .ngs-content-box button { border: none; border-radius: 4px; background: #826ec3; padding: 10px 20px; color: #fff; font-size: 17px; letter-spacing: 1px; } .ngs-content-box button:hover { background: #6965a1; } @media only screen and (max-width: 768px) { .headline-center { padding-top: 0; } .ngs-new-container { text-align: center; margin-top: 0; } .ngs-new-content { width: 90%; margin: 0 auto; } .ngs-new-content { display: inline-block; } #ngs-content-box-right, #ngs-content-box-left { width: 100%; text-align: center; } #ngs-content-box-right { margin-top: 20px; } } @media only screen and (max-width: 1170px) { .ngs-new-content { width: 90%; margin: 0 auto; } .ngs-content-box img { width: 350px; } } </style> <div class="ngs-new-container"> <div class="ngs-new-content"> <div class="ngs-content-box" id="ngs-content-box-left"> <h1>Single-Cell Sequencing</h1> <div> </div> <p>Single-cell sequencing provides analysis of thousands of individual cells within complex environments, as opposed to traditional bulk sequencing methods that only provide a representative average of all cells. With developments in microfluidics and molecular barcoding, NGS-based technologies have increasingly focused on single-cell analysis – this has allowed researchers to examine the diversity of heterogenous cell populations and uncover new biological discoveries.</p> <p>As one of three exclusive 10x Genomics Global Clinical Research Organizations (CROs) and an early adopter of the 10x Genomics<sup>®</sup> Chromium<sup>™</sup> X, Illumina<sup>®</sup> NovaSeq<sup>™</sup> X series, and PacBio<sup>®</sup> Revio<sup>™</sup> systems, we offer single-cell sequencing solutions for various research areas, including transcriptomics, epigenomics, immunogenomics, and more. Our optimized workflows, including pre-submission cryopreservation and post-submission dead cell removal, and specialized Ph.D.-level scientists maximize project flexibility, speed, and data accuracy for precise single-cell sequencing.</p> <div> </div> <p> </p> <a rel="noopener noreferrer" rel="noopener noreferrer" href="https://web.genewiz.com/ngs-inquiry" target="_blank"><button>Request Quote</button></a> </div> <div class="ngs-content-box" id="ngs-content-box-right"> <a rel="noopener noreferrer" rel="noopener noreferrer" href="https://hubs.ly/Q02xfPNk0" target="_blank"><img alt="" src="/-/media/Canva_OMICS-Webinar3_WebBanRight2.ashx?la=en&hash=F4519825383D9B87645FB75480A0229D88114087" /></a> </div> </div> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .question { width: 1170px; display: inline-block; } .question p { width: 90%; text-align: left; } .question ul { width: 90%; text-align: left; } @media screen and (max-width: 1170px) { .question { width: auto; } } </style> <div class="question"> <h2>What is single-cell sequencing and why does it matter?</h2> <p>Single-cell sequencing is a technology used to isolate and examine nucleic acid sequences—whole genomes or transcriptomes— of individual cells. This method allows for multiomic studies in cellular interactions and analysis of evolving cell populations.</p> <p>Single-cell sequencing provides a high-quality genomic picture of an individual cell, rather than a broad genomic snapshot from bulk DNA or RNA sequencing of tissue or sample. Single-cell sequencing is important in gene regulation studies and analyzing differences in gene expression between cells. Researchers can greatly benefit from single-cell sequencing in tumor studies and oncology research.</p> <p> </p> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .rna-seq-services { width: 1170px; margin: 0 auto; text-align: center; margin-bottom: 50px; } .service-container { width: 100%; text-align: center; display: flex; justify-content: space-around; } .rna-seq-service { width: 32%; text-align: center; padding: 20px 0 75px 0; position: relative; } .rna-seq-service h3 { margin: 0; margin-bottom: 15px; } .rna-seq-service p { width: 90%; margin: 0 auto; /*margin-bottom: 20px;*/ line-height: 20px; padding: 0; } #rna-seq-service-1 { background: #f0f0f0; } #rna-seq-service-1 span { display: none; } #rna-seq-service-2 { background: #f0f0f0; } #rna-seq-service-3 { background: #f0f0f0; } #rna-seq-service-4 { background: #f0f0f0; } #rna-seq-service-5 { background: #f0f0f0; } #rna-seq-service-6 { background: #f0f0f0; } #rna-seq-service-7 { background: #f0f0f0; } .rna-seq-service-btn { background: #826ec3; color: #ffffff; border: 2px solid #826ec3; padding: 10px 20px; -webkit-transition: background-color 0.2s ease-in-out; -moz-transition: background-color 0.2s ease-in-out; -o-transition: background-color 0.2s ease-in-out; transition: background-color 0.2s ease-in-out; position: absolute; left: 50%; bottom: 20px; margin-left: -60px; } .rna-seq-service-btn:hover { background: #6959a1; border: 2px solid #6959a1; color: #fff; padding: 10px 20px; } @media only screen and (max-width: 1170px) { .rna-seq-services { width: 90%; } .rna-seq-service-btn { font-size: 12px; padding: 10px 18px; } } @media only screen and (max-width: 768px) { .service-container { display: block; } .rna-seq-service { width: 100%; margin: 10px 0; padding: 10px 0 20px 0; } .rna-seq-service-btn { position: static; left: 0; right: 0; margin: 0; padding: 10px 20px; } .rna-seq-service p { margin-bottom: 20px; } } </style> <div class="rna-seq-services" id="rna-seq-services"> <h2>Single-Cell Sequencing Services</h2> <div class="service-container"> <div class="rna-seq-service" id="rna-seq-service-1"> <div class="rna-seq-service-content"> <h3>Single-Cell RNA-Seq</h3> <p><span style="display: inline !important;">Analyze transcriptome heterogeneity at the single-cell level. Azenta offers optimized workflows for 5’ and 3’ gene expression libraries to uncover cellular differences that are masked by bulk RNA sequencing.</span></p> <div> </div> </div> <a rel="noopener noreferrer" href="/en/Public/Services/Next-Generation-Sequencing/Single-Cell-RNA-Seq"><button class="rna-seq-service-btn">Learn More</button></a> </div> <div class="rna-seq-service" id="rna-seq-service-2"> <div class="rna-seq-service-content"> <h3>Single-Cell ATAC-Seq</h3> <p>Identify chromatin accessibility in the epigenome by profiling thousands of single cells in parallel, and discover how chromatin structure and DNA-binding proteins regulate gene expression in varying states and cellular processes.</p> <div> </div> </div> <a rel="noopener noreferrer" href="/en/Public/Services/Next-Generation-Sequencing/Single-Cell-ATAC-Seq"><button class="rna-seq-service-btn">Learn More</button></a> </div> <div class="rna-seq-service" id="rna-seq-service-3"> <div class="rna-seq-service-content"> <h3>Single-Cell Immuno-Profiling</h3> <p>Examine the immune repertoires of individual B and T cells by physically pairing VH/VL or α/β chains in B- or T-cell receptors, respectively, while simultaneously capturing data for gene expression, V(D)J clone types, and cell surface protein expression. </p> <div> </div> </div> <a rel="noopener noreferrer" href="/en/Public/Services/Next-Generation-Sequencing/Immunogenomics/Immuno-Profiling"><button class="rna-seq-service-btn">Learn More</button></a> </div> </div> <div> </div> <div class="service-container"> <div class="rna-seq-service" id="rna-seq-service-4"> <div class="rna-seq-service-content"> <h3>Single-Cell Multiome ATAC + RNA</h3> <p><span style="display: inline !important;">Simultaneously profile gene expression and open chromatin from the same cell with Multiome ATAC-Seq and RNA-Seq to gain deeper insights into underlying gene regulatory mechanisms with RNA and DNA readouts from every cell.</span></p> <div> </div> </div> <a rel="noopener noreferrer" href="https://web.genewiz.com/ngs-inquiry"><button class="rna-seq-service-btn">Request Quote</button></a> </div> <div class="rna-seq-service" id="rna-seq-service-6"> <div class="rna-seq-service-content"> <h3>Single-Cell Gene Expression Flex</h3> <p>Ideal for sensitive cell populations with reduced viability after cryopreservation and FFPE samples, this targeted capture panel is an excellent alternative to traditional approaches. For human and mouse samples only.</p> <div> </div> </div> <a rel="noopener noreferrer" href="https://web.genewiz.com/ngs-inquiry"><button class="rna-seq-service-btn">Request Quote</button></a> </div> <div class="rna-seq-service" id="rna-seq-service-7"> <div class="rna-seq-service-content"> <h3>Single-Cell CITE-Seq</h3> <p>Simultaneously quantify cell surface protein and transcriptomic data within a single cell readout. Can be combined with Single-Cell Immuno-Seq for comprehensive expression results.</p> <div> </div> </div> <a rel="noopener noreferrer" href="https://web.genewiz.com/ngs-inquiry"><button class="rna-seq-service-btn">Request Quote</button></a> </div> </div> <div> </div> <div class="service-container"> <div class="rna-seq-service" id="rna-seq-service-7"> <div class="rna-seq-service-content"> <h3>Regulated Single-Cell Sequencing Services</h3> <p><span style="display: inline !important;">Single-cell processing for all services listed in our GCP-compliant, CAP-accredited and CLIA-certified laboratory environment for clinical applications. </span></p> <div> </div> </div> <a rel="noopener noreferrer" href="https://web.genewiz.com/ngs-inquiry"><button class="rna-seq-service-btn">Request Quote</button></a> </div> </div> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .main-container { padding: 20px 0; } .workflow-container { width: 95%; margin: 0 auto; margin-top: 40px; } .workflow { width: 100%; margin: 0 auto; text-align: center; } .workflow-step { display: inline-block; width: 30%; vertical-align: top; padding: 5px; margin-bottom: 20px; } .workflow-step img { width: 150px; margin: 0 auto; margin-bottom: 40px; } .workflow-step h3 { text-align: center; font-size: 18px; font-family: sans-serif; border-bottom: none; } .workflow-step p { width: 80%; margin: 0 auto; text-align: center; } .workflow-icon { text-align: center; } @media only screen and (max-width: 1170px) { .workflow { text-align: left; margin: 0 auto; } .workflow-step { width: 24%; } } @media only screen and (max-width: 1000px) { .workflow-step { width: 100%; } } </style> <div class="main-container"> <h2 style="text-align: center; margin-bottom: 30px;">SINGLE-CELL sequencing workflow </h2> <div class="workflow-container"> <div class="workflow"> <div class="workflow-step"> <div class="workflow-icon"> <img alt="" src="/-/media/Images/Prepare-Samples_210x110_purple.ashx?la=en&hash=202F991CD1B771F51E527F69ADABF7A9F4E251E8" /> </div> <h3>1. Sample Submission </h3> <p>Sample types include live, cryopreserved and fixed: isolated cells, cultured cells, primary tissue, organoids and more.</p> </div> <div class="workflow-step"> <div class="workflow-icon"> <img alt="" src="/-/media/Images/Icon_210x110_CellPartitioning.ashx?la=en&hash=AC3C7E0A1BF2C6CC1141D97E3A883454B6D4F644" /> </div> <h3>2. Sample QC and Cell Partitioning </h3> <p>Assessment of cell counting, viability testing and <a rel="noopener noreferrer" rel="noopener noreferrer" href="https://web.azenta.com/single-cell-dcr-tech-note?__hstc=251210969.531b7d6279fdab71a9b2db01e6d04a4f.1696511138918.1707413297843.1707911659128.95&__hssc=251210969.68.1707911659128&__hsfp=2731169240" target="_blank">dead cell removal</a>, when indicated, maximizes sample quality prior to loading. Cells and barcoded beads are then isolated in droplets using the 10x Genomics Chromium X.</p> </div> <div class="workflow-step"> <div class="workflow-icon"> <img alt="" src="/-/media/Library-Preparation---210-x-110.ashx?la=en&hash=E3DC81CFCA4D1D12DD74175BA389D3648D91EE38" /> </div> <h3>3. Library Preparation</h3> <p>Unique barcodes for each individual cell are added to RNA or DNA prior to library preparation. Short-read and long-read library preparation options are available.</p> </div> <div class="workflow-step"> <div class="workflow-icon"> <img alt="" src="/-/media/Images/Icon_210x110_Sequence.ashx?la=en&hash=F840DDDB61C02B6F2C0C5C024690F1D3E5C88BA2" /> </div> <h3>4. Sequencing</h3> <p>Barcoded libraries are pooled and sequenced on the Illumina NovaSeq X Plus or PacBio Revio system, as indicated by library preparation, for high-throughput characterization.</p> </div> <div class="workflow-step"> <div class="workflow-icon"> <img alt="" src="/-/media/Data-Analysis---210-x-110.ashx?la=en&hash=A07E36DB27F670A8B345E68151DF4EBDCA5E02CC" /> </div> <h3>5. Data Analysis</h3> <p>Receive custom analysis and visualize results through interactive software. Complimentary Ph.D.-level support is available post-delivery to help drive biological insights.</p> </div> </div> </div> </div> </div> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Default margin-top-0 margin-bottom-0 padding-top-20 padding-bottom-0"> <div class="container"> <div class="headline-center"> <h2>Single-Cell Sequencing Features & Benefits</h2> <p></p> </div> <ul class="list-unstyled row "> <li class='col-sm-4'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 margin-bottom-0 padding-top-0 padding-bottom-0'> <div class="row"> <img src="/-/media/10x-Genomics---CSP-logo----210-x-110.ashx?h=110&la=en&w=210&hash=74F8296ADC89A64D0677E9E48569E770E20D6081" alt="Building" width="210" height="110" title="10x Genomics small" /> </div> <div class="row"> <br /> <strong>10x Genomics Certified Service Provider</strong> </div> <div class="row"> <p>And one of three exclusive 10x Global Clinical Research Organizations (CROs)</p> </div> </div> </li>  <li class='col-sm-4'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 margin-bottom-0 padding-top-0 padding-bottom-0'> <div class="row"> <img src="/-/media/Images/Icon_210x110_ProjectUpdates.ashx?h=111&la=en&w=210&hash=B12AE37DF83C314CBC3BC89BFFDCC11E705160DF" alt="Building" width="210" height="111" /> </div> <div class="row"> <br> <strong>Real-Time Project Updates</strong> </div> <div class="row"> <p>Through our online system </p> </div> </div> </li>  <li class='col-sm-4'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 margin-bottom-0 padding-top-0 padding-bottom-0'> <div class="row"> <img src="/-/media/Images/Icon_210x110_PhDSupport.ashx?h=111&la=en&w=211&hash=FA55658565B2057C4E4020CE3869A6A48859967A" alt="Building" width="211" height="111" /> </div> <div class="row"> <br> <strong>Ph.D.-Level Support</strong> </div> <div class="row"> <p>At every step</p> </div> </div> </li>  </ul> <div class="row headline-center"> </div> </div> </div> <script type="text/javascript" src="/assets/plugins/counter/jquery.counterup.min.js"></script> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".row .category").find("img").addClass("img-responsive"); }); </script> <div class='Component-Frame pull-center Multi-column-TextBullet-Layout Component-BackGround-Default margin-top-0 margin-bottom-0 padding-top-0 padding-bottom-0'> <div class="container"> <div class="headline-center"> <a href="#single-cell-cs"></a> <div id="single-cell-cs"> </div> </div> <div class="headline-left"> <a href="#single-cell-cs"></a> <div id="single-cell-cs"> </div> </div> <div class="row category"> <div class="col-md-6 col-sm-6"> <div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-gray icon-4x fa fa-check" style="border:none;"></i></div> <div class="content-boxes-in-v3"> <strong>Early adopter of 10x Genomics Chromium</strong> with optimized workflows that maximize project flexibility, speed, and data accuracy </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-gray icon-4x fa fa-check" style="border:none;"></i></div> <div class="content-boxes-in-v3"> <strong>Highest throughput sequencing platforms</strong>, including the Illumina NovaSeq, provide cost-effective single-cell sequencing solutions </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-gray icon-4x fa fa-check" style="border:none;"></i></div> <div class="content-boxes-in-v3"> <strong>Samples accepted at different stages of the 10x workflow</strong> including cells, Gel Beads in Emulsion (GEMs), or 10x barcoded cDNA libraries for maximum workflow flexibility </div> </div> </div> <div class="col-md-6 col-sm-6"> <div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-gray icon-4x fa fa-check" style="border:none;"></i></div> <div class="content-boxes-in-v3"> <strong>Proprietary cell freezing protocol</strong><span style="color: #404040;"> maintains cell viability during transit and provides a convenient method to ship samples<br> </span> </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-gray icon-4x fa fa-check" style="border:none;"></i></div> <div class="content-boxes-in-v3"> <strong><a rel="noopener noreferrer" rel="noopener noreferrer" href="https://web.azenta.com/single-cell-dcr-tech-note" target="_blank">Dead cell removal</a></strong> to improve data quality, especially for projects with suboptimal samples </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-gray icon-4x fa fa-check" style="border:none;"></i></div> <div class="content-boxes-in-v3"> <strong>Send us flash-frozen tissues</strong> for nuclei extraction and high-quality single-cell sequencing gene expression data </div> </div> </div> </div> </div> </div><script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Gray margin-top-0 margin-bottom-0 padding-top-10 padding-bottom-0 "> <div class=" container"> <div class="headline-center"> <h2>Single-Cell Sequencing Technical Resources</h2> <p></p> </div> <ul class="list-unstyled row "> <li class='col-sm-4'> <a href='https://web.genewiz.com/hubfs/2024-02%20GEN%20NGS%20Single-Cell%20Webpage%20Update/GENEWIZ%2010x%20Genomics%20scRNA-Seq%20Example%20Report.html' target='blank'> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-0 padding-top-10 padding-bottom-0'> <div class="row"> <img src="/-/media/Example-Data---210-x-110.ashx?h=110&la=en&w=210&hash=C7F77EDE000AABC4CB29A27B6DB53C6F932C4B13" alt="Building" width="210" height="110" title="Example Data Small" /> </div> <div class="row"> <h3>Example Data</h3> </div> <div class="row"> </div> </div> </a> </li>  <li class='col-sm-4'> <a href='https://www.genewiz.com/en/Public/Resources/Sample-Submission-Guidelines/Next-Generation-Sequencing-Sample-Submission-Guidelines' target=''> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-0 padding-top-10 padding-bottom-0'> <div class="row"> <img src="/-/media/Images/Prepare-Samples_210x110_purple.ashx?h=111&la=en&w=211&hash=8626211B8F77D0FB6757AF5D5E5A2960B52652D6" alt="Building" width="211" height="111" /> </div> <div class="row"> <h3>Sample Submission Guidelines</h3> </div> <div class="row"> </div> </div> </a> </li>  <li class='col-sm-4'> <a href='https://web.genewiz.com/single-cell-faq' target='blank'> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-0 padding-top-10 padding-bottom-0'> <div class="row"> <img src="/-/media/Images/FAQ_210x110_purple.ashx?h=111&la=en&w=211&hash=3E72FE67CF61B960C891CE902CD430B183BB8BF7" alt="Building" width="211" height="111" /> </div> <div class="row"> <h3>Frequently Asked Questions</h3> </div> <div class="row"> </div> </div> </a> </li>  </ul> <div class="row headline-center"> </div> </div> </div><div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> body { margin: 0; } .tech-resources-container { width: 1170px; margin: 0 auto; padding: 20px; } .tech-resources-container h2 { text-align: center; border-bottom: none; } .tech-resource { display: flex; align-items: center; flex-direction: row; margin-bottom: 35px; } .resource { flex-grow: 1; } .resource-right h3, .resource-right p { width: 90%; margin: 0 auto; border-bottom: none; text-align: left; } .resource button { padding: 5px 15px; border: none; border-radius: 4px; background: #826ec3; color: #fff; font-size: 15px; font-weight: lighter; letter-spacing: 1px; margin-top: 15px; -webkit-transition: ease-in-out 0.2s; -moz-transition: ease-in-out 0.2s; -o-transition: ease-in-out 0.2s; transition: ease-in-out 0.2s; } .resource button:hover { background: #6959a1; } @media only screen and (max-width: 800px) { .tech-resource { flex-direction: column; text-align: center; } .resource-right h3, .resource-right p { text-align: center; } } @media only screen and (max-width: 1170px) { .tech-resources-container { width: 80%; margin: 0 auto; } } </style> <div style="width: 100%; background-color: #f0f0f0; padding: 20px; margin: 0;margin-top: -20px;"> <div class="tech-resources-container"> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13028-D_10xDDN_TechResource_Laptop-(1).ashx?la=en&hash=87E7B41D8AEBD5438E9D32F3F6D2583072328D5E" /> </div> <div class="resource resource-right"> <h3>Webinar | Expanding Opportunities for Single-Cell RNA Sequencing</h3> <p>Single-cell sequencing can be a powerful tool used to discover new targets for therapeutic development. In this webinar, co-sponsored by Azenta and 10x Genomics, learn about the latest developments in single-cell technologies and their use in uncovering novel therapeutic discoveries. <br /> <a href="https://web.genewiz.com/webinar/expanding-opportunities-single-cell-rna-sequencing?utm_campaign=2022-06+GEN+NGS+-+10x+Genomics+Webinar&utm_source=eu+single-cell+ov&utm_medium=tech+resources" target="_blank"> <button>Watch Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13057-D_Transcriptomics-Webinar_TechResource_Laptop.ashx?la=en&hash=C9D7CAA35F4E698EB28DFEE74F8ADB2FA09B5276" /> </div> <div class="resource resource-right"> <h3>Webinar Series | Advancing Transcriptomics: Gene Expression Screening, Single-Cell RNA-Seq, and Beyond</h3> <p>With this two-part webinar series, go beyond traditional transcriptomics and learn about the various NGS approaches available for gene expression analysis. In part 1, we take an in-depth look at various gene expression approaches, including RNA-Seq, single-cell RNA-Seq, digital spatial profiling, and more. In part 2, we explore the data generated from these approaches and how they can complement each other and confirm findings. <br /> <a href="https://web.genewiz.com/webinar/advancing-transcriptomics" target="_blank"> <button>Watch Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13020-D_10xGenomics-Webinar_Web-Tech-Thumb.ashx?la=en&hash=4DBA0EBF56691CC76A3EE5B356402DA0A3C63C06" /> </div> <div class="resource resource-right"> <h3>Webinar: Improving Single-Cell RNA-Seq Workflow Efficiency to Scale Clinical Research</h3> <p>In this webinar co-hosted by Azenta Life Sciences and 10x Genomics, learn how Clinical Research Organizations (CROs) provide expertise across the single-cell RNA sequencing (scRNA-Seq) workflow, including sample prep and experimental execution. This enables pharmaceutical and biotech clients to perform single-cell analysis at greater scale, efficiency, and reproducibility for clinical research. <br /> <a href="https://web.genewiz.com/webinar/single-cell-rna-seq-workflow" target="_blank"> <button>Watch Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/SCS_Blog_US_Web-Tech-Thumb-220x160-(1).ashx?la=en&hash=0FCF9D182D2D0779BF318D3A9899A0E110349719" /> </div> <div class="resource resource-right"> <h3>Top 3 Factors to Consider Before Starting a Single-Cell Sequencing Project</h3> <p>With several commercial platforms available, high-throughput single-cell sequencing is now more accessible than ever. In this article, we’ll touch upon the 3 most important factors to consider before embarking on your single-cell project to ensure you select the right NGS approach for your research. <br /> <a href="https://www.azenta.com/learning-center/blog/single-cell-sequencing-top-3-factors-consider" target="_blank"> <button>Read Article</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/13017-D_AGBT-Poster_TechResource-Thumb.ashx?la=en&hash=390D91B2D90D084A49CB77C97260514339851EEC" /> </div> <div class="resource resource-right"> <h3>Poster | Utilizing an alternate cell fixation method to expand opportunities for single-cell RNA sequencing </h3> <p>The complexity of sample preparation for single-cell sequencing remains a bottleneck for researchers interested in performing analysis at the cellular level. In this poster, we highlight an alternative sample preparation and processing workflow to standard methods that help to broaden the usage of single-cell sequencing approaches. <br /> <a href="https://web.genewiz.com/poster/alternate-cell-fixation-method-single-cell-rna-sequencing" target="_blank"> <button>Download Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/13017_Single-Cell_CS-Thumbnail.ashx?la=en&hash=CA3435D516373193B8E9B2CD047EE05F0A59DDDA" /> </div> <div class="resource resource-right"> <h3>Case Study: Single-Cell RNA-Seq Analysis Identifies Rare Drug-Resistant Cancer Stem Cells</h3> <p>Cell populations are rarely homogeneous and synchronized in their characteristics. Standard RNA-Seq approaches are limited to reporting general expression levels thus omitting minor subpopulation profiles. This study highlights new single-cell RNA sequencing capabilities for identifying rare cells, characterizing their transcriptomes, and discovering potential biomarkers. <br /> <a href="https://web.genewiz.com/case-study/single-cell-rna-seq-identifies-rare-cancer-stem-cells" target="_blank"> <button>Download</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/73025-D_SIngle-Cell_TechNote-Thumb.ashx?la=en&hash=69839DAA12E154A75ADB9706BAF4F1FE2DC95AD0" /> </div> <div class="resource resource-right"> <h3>Tech Note: Add More Life to Your Data: Optimizing Single-Cell RNA-Seq with Dead Cell Removal</h3> <p id="Single-Cell-Blog">Obtaining samples with high cell viability can be difficult for many experiments but is necessary for success on the 10x Genomics<sup>®</sup> Chromium™ platform. This tech note describes how Azenta scientists used optimized single-cell workflows, including dead cell removal, to overcome low viability and generate high-quality sequencing data. <br /> <a href="https://web.genewiz.com/tech-note/single-cell-sequencing-dead-cell-removal" target="_blank"> <button>Download Now</button> </a> </p> </div> </div> <span id="Blog" class="anchor"></span> </div> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <div class="container"> <div class="row"> <h2>NGS Platforms</h2> <p>For information on our NGS platforms as well as recommended configurations of your projects, please visit the <a href="https://www.genewiz.com/en/Public/Resources/NGS-Platforms">NGS Platforms</a> page. <em>Azenta does not guarantee data output or quality for sequencing-only projects.</em> </p> </div> <div class="row row-centered margin-top-30"> <div class="col-sm-3 col-centered"><img alt="Illumina" src="/-/media/hires-illumina-logo-rgb_new.ashx?w=200&la=en&hash=2DE7778E5877DA9F3D063A9FAF021DA575ECF223" style="width: 200px;" /></div> <div class="col-sm-3 col-centered"><img alt="PacBio" src="/-/media/PacBio-CSP_logo.ashx?w=200&la=en&hash=1568DC13B370C032463997ED7BC5591C1FECF672" style="width: 200px;" /></div> <div class="col-sm-3 col-centered"><img alt="10x Genomics" src="/-/media/10x-Genomics-CSP_logo.ashx?w=200&la=en&hash=2584354CF0810D46E980E04C8C03461D332EE516" style="width: 200px;" /></div> <div class="col-sm-3 col-centered"><img alt="NanoString" src="/-/media/Images/Resources/NGS-Platforms-and-Specifications/NanoString_resized_logo.ashx?w=200&la=en&hash=A22CDFCF6A16A9884C633E8C2EF98B468325D130" style="width: 200px;" /></div> </div> <div class="row row-centered margin-top-30"> <div class="col-sm-3 col-centered"><img alt="Nanopore" src="/-/media/ONT_ServiceCertified_logo-cut.ashx?w=200&la=en&hash=4140BDC9974099FF45B0BBB29FCC746FEDCFBCC7" style="width: 200px;" /></div> <div class="col-sm-3 col-centered"><img alt="Olink" src="/-/media/Olink-Certified-Service-Provider-cut.ashx?w=200&la=en&hash=A8C78860807705F8B01299DE5A728848734F53EF" style="width: 200px;" /></div> </div> <br /> <br /> </div> </div> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10"> <div class="container"> <div class="headline-center"> <h2>Related Services</h2> <p></p> </div> <ul class="list-unstyled row row row-centered"> <li class='col-sm-4'> <a href='/Public/Services/Next-Generation-Sequencing/RNA-Seq' target=''> <div class='SingleIcon headline-center Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img 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