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Biomarkers - Research Areas - GENEWIZ

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<img src="/-/media/Images/Home/icons/Purple-Icons/snp-genoytping-icon_Purple_DESIGN.ashx?h=111&amp;la=en&amp;w=211&amp;hash=138A9D284D1F4FA0DF18BBE8CDE9152E6EAA0230" alt="" width="211" height="111" /> </div> <div class="row headline-center"> SNP Genotyping </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Molecular-Genetics/PCR-Plus-Sequencing-CRISPR-Analysis-Package'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/PCR-PLUS-SEQUENCING-CRISPR-ANALYSIS-icon_210x110_Purple_DESIGN.ashx?h=111&amp;la=en&amp;w=211&amp;hash=2868F8C7DD7CE76FE77AAA2101B456D7878AE4AD" alt="PCR PLUS SEQUENCING CRISPR ANALYSIS PACKAGE" width="211" height="111" /> </div> <div class="row headline-center"> PCR Plus Sequencing CRISPR Analysis Package </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = 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style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Molecular-Genetics/Fragment-Analysis'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/Fragment-Analysis_110x210_Purple.ashx?h=110&amp;la=en&amp;w=210&amp;hash=8D25CD819A79D3F5C6E2F66CE25B9A22E0E421A9" alt="" width="210" height="110" /> </div> <div class="row headline-center"> Fragment Analysis </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Molecular-Genetics/PCR-Solutions'"> <div class="row headline-center margin-bottom-10"> </div> <div class="row headline-center"> Quantitative PCR &amp; Digital PCR <sup style="color:#826ec3;"><strong>NEW&nbsp;</strong></sup> </div> </div> </div> </div> </div> </li> </ul> </li> <li class="dropdown mega-menu-fullwidth"> <a href="/en/Public/Services/Gene-Synthesis" class="dropdown-toggle" data-toggle="dropdown" style="color: #585f69;padding-left:5px;padding-right:5px;top:20px; font-size:11px;"> DNA &amp; RNA Synthesis </a> <ul class="dropdown-menu"> <li> <div class="mega-menu-content disable-icons"> <div class="container"> <div class="row "> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Gene-Synthesis/Gene-Synthesis'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/gene-synthesis-standard_110x210_Purple.ashx?h=110&amp;la=en&amp;w=210&amp;hash=9589F8499B1EAED1BCE995CD181603727F3476A8" alt="" width="210" height="110" /> </div> <div class="row headline-center"> Gene Synthesis </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Gene-Synthesis/Antibody-DNA-Synthesis'"> <div class="row headline-center margin-bottom-10"> </div> <div class="row headline-center"> Antibody Synthesis </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Gene-Synthesis/AAV-Plasmid-Synthesis'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/GWZ_NGS_WGS_Web_Icon_Purple.ashx?h=111&amp;la=en&amp;w=211&amp;hash=575FF0ADB583ABD8C22E3A9657928E65B4D56174" alt="RNA Seq" width="211" height="111" /> </div> <div class="row headline-center"> AAV Plasmid Synthesis </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Gene-Synthesis/Gene-Fragments'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/Fragment-Gene_Web-Icon-Service_Purple_DESIGN.ashx?h=111&amp;la=en&amp;w=211&amp;hash=8B6C44621515B4D66E237B533867CEBF28597388" alt="" width="211" height="111" /> </div> <div class="row 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Recombinant Antibody Production <sup style="color:#826ec3;"><strong>NEW&nbsp;</strong></sup> </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Gene-Synthesis/Custom-mRNA-Synthesis'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Antibody-Services.ashx?h=204&amp;la=en&amp;w=247&amp;hash=0CF3B7E0147E6E5EC28A2B034181B0255773B79E" alt="" width="247" height="204" /> </div> <div class="row headline-center"> Custom mRNA Synthesis <sup style="color:#826ec3; font-weight: bold;">NEW</sup> </div> </div> </div> </div> </div> </li> </ul> </li> <li class="dropdown mega-menu-fullwidth"> <a href="/en/Public/Services/Oligo" class="dropdown-toggle" data-toggle="dropdown" style="color: #585f69;padding-left:5px;padding-right:5px;top:20px; font-size:11px;"> Oligo Synthesis Services </a> <ul class="dropdown-menu"> <li> <div class="mega-menu-content disable-icons"> <div 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'/en/Public/Services/Clinical-Services/Regulatory'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/GLP-compliant-Confirmatory-Sequencing_110x210_Purple.ashx?h=110&amp;la=en&amp;w=210&amp;hash=6E17481E2B90ACF9B7789BF343BD5E801683A447" alt="" width="210" height="110" /> </div> <div class="row headline-center"> GLP-Compliant Overview </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Clinical-Services/GLP-compliant-Confirmatory-Sequencing'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/GLP-compliant-Confirmatory-Sequencing_110x210_Purple.ashx?h=110&amp;la=en&amp;w=210&amp;hash=6E17481E2B90ACF9B7789BF343BD5E801683A447" alt="" width="210" height="110" /> </div> <div class="row headline-center"> GLP Confirmatory Sequencing </div> </div> <div class="col-md-3" 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Plasmid Prep </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Clinical-Services/Nucleic-Acid-Extraction'"> <div class="row headline-center margin-bottom-10"> <img src="/-/media/Images/Home/icons/Purple-Icons/Nucleic-Acid-Extraction_110x210_Purple.ashx?h=110&amp;la=en&amp;w=210&amp;hash=9C72E25F36E011F6ACD2D7CFB169F12713A6596D" alt="" width="210" height="110" /> </div> <div class="row headline-center"> GLP Nucleic Acid Extraction </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Clinical-Services/Biofluid-Processing-Overview'"> <div class="row headline-center margin-bottom-10"> </div> <div class="row headline-center"> Biofluid Processing </div> </div> <div class="col-md-3" style="cursor:pointer;padding-top:20px;padding-bottom:20px;" onclick="location.href = '/en/Public/Services/Clinical-Services/CLIA-Integration-Site-Analysis'"> <div class="row headline-center margin-bottom-10"> </div> <div class="row headline-center"> CLIA Integration Site Analysis <sup style="color:#826ec3; font-weight: bold;">NEW</sup> </div> </div> </div> </div> </div> </li> </ul> </li> </ul> </div> </div><!--/navbar-collapse--> </div> </div> <!-- End Navbar --> </div> <!--=== End Header v6 ===--> <br /><br /> <script type="text/javascript" src="/assets/plugins/counter/jquery.counterup.min.js"></script> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $("div[id^=Desc]").find("img").addClass("img-responsive"); }); </script> <div class='Component-Frame pull-center Two-Column-Text-Image-LR-Layout-v1 Component-BackGround-Gray margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="container"> <div class="row"> <div class="col-md-7"> <h1 class="title-v2"><h1>BIOMARKERS</h1> </h1> With the emergence of personalized medicine and the ability to predict medical diagnosis/prognosis based on a patient’s genetic makeup, more and more researchers have begun to incorporate biomarker analysis into their research.<br> <br> </div> <div class="col-md-5" id="DescImg"> <img src="/-/media/Images/Research-Area/Biomarkers/icons/375x561/Biomarkers_375x561.ashx?h=267&amp;la=en&amp;w=400&amp;hash=B678762DF845913BAC4488E7B89CBF965234EDDC" alt="Building" width="400" height="267" /> </div> </div> </div> </div> <script type="text/javascript" src="/assets/plugins/counter/jquery.counterup.min.js"></script> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".row .category").find("img").addClass("img-responsive"); }); </script> <div class='Component-Frame pull-center Multi-column-TextBullet-Layout Component-BackGround-Default margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="container"> <div class="headline-center"> <h2>Genomics in Biomarkers</h2> <br /> </div> <div class="headline-left"> <br> </div> <div class="row category"> <div class="col-md-6 col-sm-6"> <div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> Basic scientists identify and analyze molecular biomarkers in their pathways of interest to get a clearer understanding of these pathways and the resulting physiology or pathology. </div> </div><div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> Drug developers incorporate biomarker discovery into their R&amp;D, pre-clinical, and clinical workflows to develop targeted therapies which will result in better efficacy. Some biomarkers that have resulted in effective targeted drugs include BRAF, HER2, EGFR, and KRAS to name a few. Biomarkers have recently taken on added significance in cancer diagnosis and treatment but also play an important role in various other therapeutic areas.<br /> </div> </div> </div> <div class="col-md-6 col-sm-6"> <div class="content-boxes-v3 margin-bottom-20"> <div class="col-md-2"><i class="BlueCheck icon-custom icon-bg-light icon-4x fa fa-check"></i></div> <div class="content-boxes-in-v3"> In medicine, healthcare practitioners rely on pharmacogenomics testing to analyze a patient’s genomic profile in order to accurately prescribe the most effective medications with as few side-effects as possible.<br> </div> </div> </div> </div> </div> </div><script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Default biomarkers margin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10"> <div class="container"> <div class="headline-center"> <h2>Applications</h2> <br> <p><p>GENEWIZ offers a number of genomics solutions to assist in biomarker research and discovery.</p> <br></p> </div> <ul class="list-unstyled row "> <li class='col-sm-3'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/GWZ_NGS_RNAseq_Web_Icon_Purple.ashx?h=111&amp;la=en&amp;w=211&amp;hash=84A797481570CEA4593978E5CA7294740B782025" alt="Building" width="211" height="111" /> </div> <div class="row"> <h3>RNA-Seq</h3> </div> <div class="row"> <p class="text-left">The throughput of RNA-Seq allows researchers to analyze the entire transcriptome of an organism and thereby discover molecular biomarkers related to gene expression, alternative transcripts or splicing events.</p><br> <p class="text-left"><a href="/Public/Services/Next-Generation-Sequencing/RNA-Seq" class="blue-text" style="padding: 10px; background-color: #826ec3;color:#fff;">Learn More <em class="icon-3x fa fa-angle-right"></em></a></p> <br> <br> <br> <br> </div> </div> </li> <!--target=""--> <li class='col-sm-3'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/whole-genome-sequencing_110x210_Purple.ashx?h=110&amp;la=en&amp;w=210&amp;hash=6FBD1B8C2E3AA5A93B5D4ABD4142E4BB8A1D9415" alt="Building" width="210" height="110" /> </div> <div class="row"> <h3>Whole Genome Sequencing</h3> </div> <div class="row"> <p class="text-left">Full-service whole genome sequencing allows the comprehensive analysis of entire genomes to reveal implicated genotypes or discover previously unknown SNPs, genes, or other biomarkers. </p><br> <p class="text-left"><a href="/Public/Services/Next-Generation-Sequencing/Whole-Genome-Sequencing" class="blue-text" style="padding: 10px; background-color: #826ec3;color:#fff;">Learn More <em class="icon-3x fa fa-angle-right"></em></a></p> <br> <br> <br> </div> </div> </li> <!--target=""--> <li class='col-sm-3'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 margin-bottom-30 padding-top-10 padding-bottom-10'> <div class="row"> <img src="/-/media/Images/Home/icons/Purple-Icons/gene-synthesis_110x210_Purple.ashx?h=110&amp;la=en&amp;w=210&amp;hash=61237659C1B6D3300B1F2AB38BCEFFCBCDE7F7A3" alt="Building" width="210" height="110" /> </div> <div class="row"> <h3>Gene Synthesis</h3> </div> <div class="row"> <p class="text-left">Advance your proteomic biomarker studies by using our gene synthesis services to quickly obtain your gene of interest.</p><br> <p class="text-left"><a href="/Public/Services/Gene-Synthesis" class="blue-text" style="padding: 10px; 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