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(PDF) Antimicrobial Activity and Phytochemical Analysis of Selected Indian Folk Medicinal Plants | Kavitha Thirumurugan - Academia.edu
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window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":698487,"created_at":"2011-06-27T02:24:22.766-07:00","from_world_paper_id":2294334,"updated_at":"2024-11-11T11:11:23.389-08:00","_data":{"publisher":"ijpsr.info","grobid_abstract":"The success of chemotherapy lies in the continuous search for new drugs to counter the challenge posed by resistant strains. Methanol extracts of six plant species traditionally used in Indian folklore medicine for the treatment of various bacterial and fungal infections were investigated for in vitro antimicrobial activity against pathogens namely Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candida albicans and Aspergillus niger by disc diffusion method. Methanol extracts of Eugenia jambolana and Cassia auriculata showed the highest toxicity against all the bacteria. The plant extracts showed antibacterial activity but not antifungal activity against any of the fungi used. Minimum inhibitory concentration (MIC) assay were determined for these two extracts against bacteria. E. jambolana revealed the highest antimicrobial activity at a minimum concentration (0.75 mg/ml) against S. aureus. The phytochemical analysis carried out revealed the presence of coumarins, flavanoids, glycosides, phenols, tannins, saponins and steroids. Alkaloids were not detected from any of the plant extracts under study. The results provide justification for the use of the plants in folk medicine to treat various infectious diseases.","publication_name":"steroids","grobid_abstract_attachment_id":"3925035"},"document_type":"paper","pre_hit_view_count_baseline":0,"quality":"high","language":"en","title":"Antimicrobial Activity and Phytochemical Analysis of Selected Indian Folk Medicinal Plants","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [322633]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":3925035,"attachmentType":"pdf"}"><img alt="First page of “Antimicrobial Activity and Phytochemical Analysis of Selected Indian Folk Medicinal Plants”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/3925035/mini_magick20190427-577-bphrr1.png?1556379688" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Antimicrobial Activity and Phytochemical Analysis of Selected Indian Folk Medicinal Plants</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="322633" href="https://vit.academia.edu/KavithaThirumurugan"><img alt="Profile image of Kavitha Thirumurugan" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/322633/9829843/10954715/s65_kavitha.thirumurugan.jpg" />Kavitha Thirumurugan</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">steroids</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">5 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 698487; 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In the present study, five indigenous plants of Assam namely Oldenlandia corymbosa, Ricinus communis, Lpomea aquatica, Xanthium strumarium, Mentha piperita were analyzed for various Phytochemicals present and their antimicrobial activity. Methods: Phytochemical screening tests was conducted for five plant species and found that extract contains a variety of Phytochemicals like saponins, tannins, flavonoids, terpenoids, glycosides and reducing sugars and among which there is higher level of precipitation for phenol and flavonoids. As they are essential source of antimicrobial agents against pathogens, their extract were tested for its antimicrobial activity by well diffusion method using Nutrient agar against human pathogenic bacteria like Staphylococcus aureus, Escherichia coli. Results: The study plant extract of Xanthium strumarium(leaves, roots) and Mentha piperita(stem) had shown a strong antimicrobial activity against Staphylococcus aureus and the plant extract of Ricinus communis(leaves ,stem, roots), Lpomea aquatica (stem)had shown antimicrobial activity against Escherichia coli. Oldenlandia corymbosa hadn't shown antimicrobial activity for both Staphylococcus aureus and Escherichia coli. This study provided evidence to confirm the presence of various medicinally important bioactive compounds or Phytochemicals that has got biological importance and it justifies their use in the traditional medicines for the treatment of different diseases and this findings suggest that the selected plant extracts possesses antimicrobial properties that could be used for biological control of bacterial cultures and this bioactive compounds serve as a source of antimicrobial agents against human pathogens.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Phytochemical Analysis of Traditional Medicinal Plants and their Antimicrobial Activity: An Experience from North East India","attachmentId":68649491,"attachmentType":"pdf","work_url":"https://www.academia.edu/50781872/Phytochemical_Analysis_of_Traditional_Medicinal_Plants_and_their_Antimicrobial_Activity_An_Experience_from_North_East_India","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/50781872/Phytochemical_Analysis_of_Traditional_Medicinal_Plants_and_their_Antimicrobial_Activity_An_Experience_from_North_East_India"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="45444422" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/45444422/Phytochemical_Analysis_and_Antimicrobial_Activity_of_Various_Indigenous_Plant_Species">Phytochemical Analysis and Antimicrobial Activity of Various Indigenous Plant Species</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="6079060" href="https://independent.academia.edu/IJRASETPublication">IJRASET Publication</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal for Research in Applied Science & Engineering TechnologyInternational Journal for Research in Applied Science & Engineering Technology, 2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Plants in the nature constitute various unidentified and excellent properties that can be used for various different purposes including creation of new drugs and therapies. The methanol extract of six medicinal plants i.e., Azadirachta indica (Neem) Calotropis procera (Aakh), Saraca asoca (Ashok), Ocimum tenuiflorum (Tulsi), Asparagus racemosus (Shatavari) and Withania somnifera (Ashwagandha) showed significant antibacterial activity against Escherichia coli, and antifungal activity against Aspergillus niger. Ocimum tenuiflorum(Tulsi) and Asparagus racemosus(Shatavari) leaf extract showed highest antimicrobial activity against E.coli and A.niger. The invitro antimicrobial activity was performed by agar disc diffusion method. The use of plant extracts with known antimicrobial properties, can be of great significance in therapeutic treatments. The study also prove that several plant extracts can be useful in preservation of food articles and constitution of several food preservatives. The presence of phytochemicals is medicinally important for formulation of many therapeutic drugs.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Phytochemical Analysis and Antimicrobial Activity of Various Indigenous Plant Species","attachmentId":65955483,"attachmentType":"pdf","work_url":"https://www.academia.edu/45444422/Phytochemical_Analysis_and_Antimicrobial_Activity_of_Various_Indigenous_Plant_Species","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/45444422/Phytochemical_Analysis_and_Antimicrobial_Activity_of_Various_Indigenous_Plant_Species"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="4117530" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/4117530/Screening_of_methanol_and_acetone_extract_for_antimicrobial_activity_of_some_medicinal_plants_species_of_Indian_folklore">Screening of methanol & acetone extract for antimicrobial activity of some medicinal plants species of Indian folklore</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="2180018" href="https://pritisajja.academia.edu/FarzinParabia">Farzin Parabia</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Screening of methanol \u0026 acetone extract for antimicrobial activity of some medicinal plants species of Indian folklore","attachmentId":31635123,"attachmentType":"pdf","work_url":"https://www.academia.edu/4117530/Screening_of_methanol_and_acetone_extract_for_antimicrobial_activity_of_some_medicinal_plants_species_of_Indian_folklore","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/4117530/Screening_of_methanol_and_acetone_extract_for_antimicrobial_activity_of_some_medicinal_plants_species_of_Indian_folklore"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="103603238" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/103603238/PHYTOCHEMICAL_PROFILES_OF_THREE_TRADITIONAL_MEDICINAL_PLANTS_AND_ITS_ANTIMICROBIAL_ACTIVITIES">PHYTOCHEMICAL PROFILES OF THREE TRADITIONAL MEDICINAL PLANTS AND ITS ANTIMICROBIAL ACTIVITIES</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="265496504" href="https://independent.academia.edu/InternationalJournalofPharmacyandPharmaceuticalSciencesIJPPS">International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Pharmacy and Pharmaceutical Sciences, 2020</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective: The objective of the current study was to compare the phytochemical composition and to evaluate the antibacterial properties of Cissus qudrangularis, Cinnamomum zeylanicum and Trigonella foenum-graecum against the bacterial strains Escherichia coli and Bacillus circulans. Methods: Qualitative analysis and quantitative estimation of various phytochemical components were done using standard protocols. Antibacterial activity against gram-negative Escherichia coli and gram-positive Bacillus circulans was evaluated using standard protocol of agar well diffusion and disc diffusion assay. The zone of inhibition was calculated. Results: Preliminary phytochemical analysis showed the presence of alkaloids, saponins and tannins in all three plant extracts. In quantitative estimation, Cinnamomum zeylanicum showed high alkaloid content (22%), Cissus qudrangularis showed high saponin content (6%) Trigonella foenum-graecum showed a high concentration (4.65 mg/g) of tannin. All the three plants showed moderate antimicrobial activity. The water extract of Cinnamomum zeylanicum showed the highest zone of inhibition (13 mm) against Escherichia coli and the water extract of Trigonella foenumgraecum showed the highest zone of inhibition (11 mm) against Bacillus circulans. Conclusion: The result of this study supports the use of all the selected three medicinal plants as a source of antibacterial substance for the possible treatment of human pathogenic organisms. These plants can be further subjected to isolation of the therapeutic phytochemicals and further pharmacological evaluation.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"PHYTOCHEMICAL PROFILES OF THREE TRADITIONAL MEDICINAL PLANTS AND ITS ANTIMICROBIAL ACTIVITIES","attachmentId":103567349,"attachmentType":"pdf","work_url":"https://www.academia.edu/103603238/PHYTOCHEMICAL_PROFILES_OF_THREE_TRADITIONAL_MEDICINAL_PLANTS_AND_ITS_ANTIMICROBIAL_ACTIVITIES","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/103603238/PHYTOCHEMICAL_PROFILES_OF_THREE_TRADITIONAL_MEDICINAL_PLANTS_AND_ITS_ANTIMICROBIAL_ACTIVITIES"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="1458344" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/1458344/Antimicrobial_activity_of_Some_Ethno_medicinal_Plants_used_by_Baiga_Tribes_from_Amarkantak_India">Antimicrobial activity of Some Ethno-medicinal Plants used by Baiga Tribes from Amarkantak, India</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="1020414" href="https://independent.academia.edu/AlexanderDecker">Alexander Decker</a></div><div 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