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Medicinal Plant Research Papers - Academia.edu

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Lock","created_at":"2015-07-05T13:32:43.158-07:00","url":"https://www.academia.edu/13665034/Chemical_Constituents_and_Antimicrobial_Activity_of_Essential_Oil_of_and_lt_i_and_gt_Senna_podocarpa_and_lt_i_and_gt_Guill_et_Perr_Lock?f_ri=1134083","dom_id":"work_13665034","summary":null,"downloadable_attachments":[{"id":45086131,"asset_id":13665034,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":1688872,"first_name":"opeyemi","last_name":"avoseh","domain_name":"ufh","page_name":"opeyemiavoseh","display_name":"opeyemi avoseh","profile_url":"https://ufh.academia.edu/opeyemiavoseh?f_ri=1134083","photo":"https://0.academia-photos.com/1688872/583945/4600568/s65_opeyemi.avoseh.jpg"}],"research_interests":[{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=1134083","nofollow":false},{"id":531,"name":"Organic 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u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/56205304" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="28f0ed26e3168a9666619ee2dda4ad71" rel="nofollow" data-download="{&quot;attachment_id&quot;:71705372,&quot;asset_id&quot;:56205304,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" 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class="InlineList-item-text" data-has-card-for-ri="1957240" href="https://www.academia.edu/Documents/in/ENVIRONMENTAL_SCIENCE_AND_MANAGEMENT">ENVIRONMENTAL SCIENCE AND MANAGEMENT</a>,&nbsp;<script data-card-contents-for-ri="1957240" type="text/json">{"id":1957240,"name":"ENVIRONMENTAL SCIENCE AND MANAGEMENT","url":"https://www.academia.edu/Documents/in/ENVIRONMENTAL_SCIENCE_AND_MANAGEMENT?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3789884" href="https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences">Pharmacology and pharmaceutical sciences</a><script data-card-contents-for-ri="3789884" type="text/json">{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=56205304]'), work: {"id":56205304,"title":"Evaluation of acute and sub acute toxicity of four medicinal plants extracts used in Cameroon","created_at":"2021-10-07T01:12:20.847-07:00","url":"https://www.academia.edu/56205304/Evaluation_of_acute_and_sub_acute_toxicity_of_four_medicinal_plants_extracts_used_in_Cameroon?f_ri=1134083","dom_id":"work_56205304","summary":null,"downloadable_attachments":[{"id":71705372,"asset_id":56205304,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":87225294,"first_name":"Rose","last_name":"NGONO MBALLA","domain_name":"independent","page_name":"RoseNGONOMBALLA","display_name":"Rose NGONO MBALLA","profile_url":"https://independent.academia.edu/RoseNGONOMBALLA?f_ri=1134083","photo":"https://0.academia-photos.com/87225294/34514846/30304996/s65_rose.ngono_mballa.jpg"}],"research_interests":[{"id":980394,"name":"Acute Toxicity","url":"https://www.academia.edu/Documents/in/Acute_Toxicity?f_ri=1134083","nofollow":false},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083","nofollow":false},{"id":1957240,"name":"ENVIRONMENTAL SCIENCE AND MANAGEMENT","url":"https://www.academia.edu/Documents/in/ENVIRONMENTAL_SCIENCE_AND_MANAGEMENT?f_ri=1134083","nofollow":false},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences?f_ri=1134083","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_3405900" data-work_id="3405900" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/3405900/Antibacterial_activity_of_medicinal_plants_against_pathogens_causing_complicated_urinary_tract_infections">Antibacterial activity of medicinal plants against pathogens causing complicated urinary tract infections</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3405900" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="10fb7d70a98084dcbc7c23ea9576e4c6" rel="nofollow" data-download="{&quot;attachment_id&quot;:50296410,&quot;asset_id&quot;:3405900,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50296410/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="2886605" href="https://independent.academia.edu/PadminiRamteke">Padmini Ramteke</a><script data-card-contents-for-user="2886605" type="text/json">{"id":2886605,"first_name":"Padmini","last_name":"Ramteke","domain_name":"independent","page_name":"PadminiRamteke","display_name":"Padmini Ramteke","profile_url":"https://independent.academia.edu/PadminiRamteke?f_ri=1134083","photo":"https://0.academia-photos.com/2886605/952713/2509625/s65_padmini.ramteke.jpg"}</script></span></span></li><li class="js-paper-rank-work_3405900 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="3405900"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 3405900, container: ".js-paper-rank-work_3405900", }); });</script></li><li class="js-percentile-work_3405900 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget 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$(".js-view-count[data-work-id=3405900]").text(description); $(".js-view-count-work_3405900").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_3405900").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="3405900"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">5</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="152908" href="https://www.academia.edu/Documents/in/Urinary_tract_infection">Urinary tract infection</a>,&nbsp;<script data-card-contents-for-ri="152908" type="text/json">{"id":152908,"name":"Urinary tract infection","url":"https://www.academia.edu/Documents/in/Urinary_tract_infection?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="290432" href="https://www.academia.edu/Documents/in/Antibacterial_activity">Antibacterial activity</a>,&nbsp;<script data-card-contents-for-ri="290432" type="text/json">{"id":290432,"name":"Antibacterial activity","url":"https://www.academia.edu/Documents/in/Antibacterial_activity?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1127893" href="https://www.academia.edu/Documents/in/Indian_Pharmaceutical_Industry">Indian Pharmaceutical Industry</a>,&nbsp;<script data-card-contents-for-ri="1127893" type="text/json">{"id":1127893,"name":"Indian Pharmaceutical Industry","url":"https://www.academia.edu/Documents/in/Indian_Pharmaceutical_Industry?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1134083" href="https://www.academia.edu/Documents/in/Medicinal_Plant">Medicinal Plant</a><script data-card-contents-for-ri="1134083" type="text/json">{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=3405900]'), work: {"id":3405900,"title":"Antibacterial activity of medicinal plants against pathogens causing complicated urinary tract infections","created_at":"2013-04-27T18:28:04.447-07:00","url":"https://www.academia.edu/3405900/Antibacterial_activity_of_medicinal_plants_against_pathogens_causing_complicated_urinary_tract_infections?f_ri=1134083","dom_id":"work_3405900","summary":null,"downloadable_attachments":[{"id":50296410,"asset_id":3405900,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":2886605,"first_name":"Padmini","last_name":"Ramteke","domain_name":"independent","page_name":"PadminiRamteke","display_name":"Padmini Ramteke","profile_url":"https://independent.academia.edu/PadminiRamteke?f_ri=1134083","photo":"https://0.academia-photos.com/2886605/952713/2509625/s65_padmini.ramteke.jpg"}],"research_interests":[{"id":152908,"name":"Urinary tract infection","url":"https://www.academia.edu/Documents/in/Urinary_tract_infection?f_ri=1134083","nofollow":false},{"id":290432,"name":"Antibacterial activity","url":"https://www.academia.edu/Documents/in/Antibacterial_activity?f_ri=1134083","nofollow":false},{"id":1127893,"name":"Indian Pharmaceutical Industry","url":"https://www.academia.edu/Documents/in/Indian_Pharmaceutical_Industry?f_ri=1134083","nofollow":false},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083","nofollow":false},{"id":1371586,"name":"Multidrug Resistant","url":"https://www.academia.edu/Documents/in/Multidrug_Resistant?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_69366240 coauthored" data-work_id="69366240" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/69366240/Hypericum_triquetrifolium_Derived_Factors_Downregulate_the_Production_Levels_of_LPS_Induced_Nitric_Oxide_and_Tumor_Necrosis_Factor_%CE%B1_in_THP_1_Cells">Hypericum triquetrifolium—Derived Factors Downregulate the Production Levels of LPS-Induced Nitric Oxide and Tumor Necrosis Factor-α in THP-1 Cells</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Based on knowledge from traditional Arab herbal medicine, thisin vitrostudy aims to examine the anti-inflammatory mechanism ofHypericum triquetrifoliumby measuring the expression and release of pro-inflammatory cytokines, tumor necrosis... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_69366240" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Based on knowledge from traditional Arab herbal medicine, thisin vitrostudy aims to examine the anti-inflammatory mechanism ofHypericum triquetrifoliumby measuring the expression and release of pro-inflammatory cytokines, tumor necrosis factor-α(TNF-α) and interleukine-6 (IL-6), and inducible nitric oxide synthase (iNOS) in human monocytic cells, THP-1. The effects were assessed by measuring the levels of secretory proteins and mRNA of TNF-αand IL-6, the levels of nitric oxide (NO) secretion and the expression of iNOS in THP-1 cells. Cells were treated with 5 μg lipopolysaccharide/ml (LPS) in the presence and absence of increasing concentrations of extracts from the aerial parts ofH. triquetrifolium. During the entire experimental period, we used extract concentrations (up to 250 μg mL−1) that had no cytotoxic effects, as measured with MTT and LDH assays.Hypericum triquetrifoliumextracts remarkably suppressed the LPS-induced NO release, significantly attenuated the LPS-induced trans...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/69366240" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="17c64b9feb081540b4319a5624f2669e" rel="nofollow" data-download="{&quot;attachment_id&quot;:79490834,&quot;asset_id&quot;:69366240,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/79490834/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="213033909" href="https://independent.academia.edu/OmarSaid100">Omar Said</a><script data-card-contents-for-user="213033909" type="text/json">{"id":213033909,"first_name":"Omar","last_name":"Said","domain_name":"independent","page_name":"OmarSaid100","display_name":"Omar Said","profile_url":"https://independent.academia.edu/OmarSaid100?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-69366240">+2</span><div class="hidden js-additional-users-69366240"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/AbdalsalamKmail">Abdalsalam Kmail</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://aauj.academia.edu/SaidKhasib">Said Khasib</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-69366240'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-69366240').html(); 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The effects were assessed by measuring the levels of secretory proteins and mRNA of TNF-αand IL-6, the levels of nitric oxide (NO) secretion and the expression of iNOS in THP-1 cells. Cells were treated with 5 μg lipopolysaccharide/ml (LPS) in the presence and absence of increasing concentrations of extracts from the aerial parts ofH. triquetrifolium. During the entire experimental period, we used extract concentrations (up to 250 μg mL−1) that had no cytotoxic effects, as measured with MTT and LDH assays.Hypericum triquetrifoliumextracts remarkably suppressed the LPS-induced NO release, significantly attenuated the LPS-induced trans...","downloadable_attachments":[{"id":79490834,"asset_id":69366240,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":213033909,"first_name":"Omar","last_name":"Said","domain_name":"independent","page_name":"OmarSaid100","display_name":"Omar Said","profile_url":"https://independent.academia.edu/OmarSaid100?f_ri=1134083","photo":"/images/s65_no_pic.png"},{"id":213666444,"first_name":"Abdalsalam","last_name":"Kmail","domain_name":"independent","page_name":"AbdalsalamKmail","display_name":"Abdalsalam 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peptides","url":"https://www.academia.edu/Documents/in/Cyclic_peptides?f_ri=1134083"},{"id":161562,"name":"Alkaloids","url":"https://www.academia.edu/Documents/in/Alkaloids?f_ri=1134083"},{"id":202399,"name":"Plant Roots","url":"https://www.academia.edu/Documents/in/Plant_Roots?f_ri=1134083"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES?f_ri=1134083"},{"id":280595,"name":"Bark","url":"https://www.academia.edu/Documents/in/Bark?f_ri=1134083"},{"id":309895,"name":"Isolation","url":"https://www.academia.edu/Documents/in/Isolation?f_ri=1134083"},{"id":335984,"name":"Anti-Bacterial Agents","url":"https://www.academia.edu/Documents/in/Anti-Bacterial_Agents?f_ri=1134083"},{"id":952991,"name":"Spectroscopic Techniques","url":"https://www.academia.edu/Documents/in/Spectroscopic_Techniques?f_ri=1134083"},{"id":991641,"name":"Southern 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Medicine","url":"https://www.academia.edu/Documents/in/Iranian_Traditional_Medicine?f_ri=1134083"},{"id":586072,"name":"Plant species","url":"https://www.academia.edu/Documents/in/Plant_species?f_ri=1134083"},{"id":587952,"name":"Skin Disease","url":"https://www.academia.edu/Documents/in/Skin_Disease?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_66164403" data-work_id="66164403" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/66164403/Adaptogens_exert_a_stress_protective_effect_by_modulation_of_expression_of_molecular_chaperones">Adaptogens exert a stress-protective effect by modulation of expression of molecular chaperones</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Adaptogens are medicinal plants that augment resistance to stress, and increase concentration, performance and endurance during fatigue. Experiments were curried out with BALB/c mice taking ADAPT-232 forte, a fixed combination of three... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_66164403" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Adaptogens are medicinal plants that augment resistance to stress, and increase concentration, performance and endurance during fatigue. Experiments were curried out with BALB/c mice taking ADAPT-232 forte, a fixed combination of three genuine (native) extracts of Eleutherococcus senticocus, Schisandra chinensis and Rhodiola rosea, characterised for the content of active markers eleutherosides, schisandrins, salidroside, tyrosol and rosavin and in doses of about 30, 90 and 180 mg/kg for seven consecutive days followed by forced swimming test to exhaustion. ADAPT-232 forte strongly augments endurance of mice, increasing the time taken to exhaustion (TTE) in a dose-dependent manner from 3.0±0.5 to 21.1±1.7 min, approximately seven fold. Serum Hsp72 was measured by EIA both in normal and stressful conditions before and after swimming test. Repeated administration of adaptogen dose dependently increases basal level of Hsp72 in serum of mice from 0.8–1.5 to 5.5–6.3 pg/ml. This effect is ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/66164403" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3ec44c49913847604d6e8a58a6cad349" rel="nofollow" data-download="{&quot;attachment_id&quot;:77465189,&quot;asset_id&quot;:66164403,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/77465189/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="196666608" href="https://independent.academia.edu/LisaAndreeva">Lisa Andreeva</a><script data-card-contents-for-user="196666608" type="text/json">{"id":196666608,"first_name":"Lisa","last_name":"Andreeva","domain_name":"independent","page_name":"LisaAndreeva","display_name":"Lisa Andreeva","profile_url":"https://independent.academia.edu/LisaAndreeva?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_66164403 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="66164403"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 66164403, container: ".js-paper-rank-work_66164403", }); 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$(".js-view-count[data-work-id=66164403]").text(description); $(".js-view-count-work_66164403").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_66164403").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="66164403"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">17</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="523" href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a>,&nbsp;<script data-card-contents-for-ri="523" type="text/json">{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4083" href="https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine">Complementary and Alternative Medicine</a>,&nbsp;<script data-card-contents-for-ri="4083" type="text/json">{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a>,&nbsp;<script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=66164403]'), work: {"id":66164403,"title":"Adaptogens exert a stress-protective effect by modulation of expression of molecular chaperones","created_at":"2021-12-27T22:45:58.280-08:00","url":"https://www.academia.edu/66164403/Adaptogens_exert_a_stress_protective_effect_by_modulation_of_expression_of_molecular_chaperones?f_ri=1134083","dom_id":"work_66164403","summary":"Adaptogens are medicinal plants that augment resistance to stress, and increase concentration, performance and endurance during fatigue. Experiments were curried out with BALB/c mice taking ADAPT-232 forte, a fixed combination of three genuine (native) extracts of Eleutherococcus senticocus, Schisandra chinensis and Rhodiola rosea, characterised for the content of active markers eleutherosides, schisandrins, salidroside, tyrosol and rosavin and in doses of about 30, 90 and 180 mg/kg for seven consecutive days followed by forced swimming test to exhaustion. ADAPT-232 forte strongly augments endurance of mice, increasing the time taken to exhaustion (TTE) in a dose-dependent manner from 3.0±0.5 to 21.1±1.7 min, approximately seven fold. Serum Hsp72 was measured by EIA both in normal and stressful conditions before and after swimming test. Repeated administration of adaptogen dose dependently increases basal level of Hsp72 in serum of mice from 0.8–1.5 to 5.5–6.3 pg/ml. This effect is ...","downloadable_attachments":[{"id":77465189,"asset_id":66164403,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":196666608,"first_name":"Lisa","last_name":"Andreeva","domain_name":"independent","page_name":"LisaAndreeva","display_name":"Lisa Andreeva","profile_url":"https://independent.academia.edu/LisaAndreeva?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=1134083","nofollow":false},{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1134083","nofollow":false},{"id":44842,"name":"Phytomedicine","url":"https://www.academia.edu/Documents/in/Phytomedicine?f_ri=1134083"},{"id":48981,"name":"Molecular chaperones","url":"https://www.academia.edu/Documents/in/Molecular_chaperones?f_ri=1134083"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=1134083"},{"id":98707,"name":"Stress response","url":"https://www.academia.edu/Documents/in/Stress_response?f_ri=1134083"},{"id":354056,"name":"Plant extracts","url":"https://www.academia.edu/Documents/in/Plant_extracts?f_ri=1134083"},{"id":373895,"name":"medicinal \u0026 Aromatic plants","url":"https://www.academia.edu/Documents/in/medicinal_and_Aromatic_plants?f_ri=1134083"},{"id":442502,"name":"Forced Swim Test","url":"https://www.academia.edu/Documents/in/Forced_Swim_Test?f_ri=1134083"},{"id":725615,"name":"Mechanism of action","url":"https://www.academia.edu/Documents/in/Mechanism_of_action?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1272906,"name":"Enzyme Linked Immunosorbent Assay","url":"https://www.academia.edu/Documents/in/Enzyme_Linked_Immunosorbent_Assay?f_ri=1134083"},{"id":1993786,"name":"Cumulant","url":"https://www.academia.edu/Documents/in/Cumulant?f_ri=1134083"},{"id":2183225,"name":"Physical Endurance","url":"https://www.academia.edu/Documents/in/Physical_Endurance?f_ri=1134083"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_54089416" data-work_id="54089416" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/54089416/Root_Competition_for_Phosphorus_Between_Coconut_Multipurpose_Trees_and_Kacholam_Kaempferia_Galanga_L_In_Kerala_India">Root Competition for Phosphorus Between Coconut, Multipurpose Trees and Kacholam (Kaempferia Galanga L.) In Kerala, India</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Abstract. The magnitude of root competition 17 year-old coconut palms suffer from three year-old inter-planted multipurpose trees, Vateria indica L., Ailanthus triphysa (Dennst.) Alston. or Grevillea robusta A. Cunn. and kacholam... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_54089416" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Abstract. The magnitude of root competition 17 year-old coconut palms suffer from three year-old inter-planted multipurpose trees, Vateria indica L., Ailanthus triphysa (Dennst.) Alston. or Grevillea robusta A. Cunn. and kacholam (Kaempferia galanga L.), a ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/54089416" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9ff183d5fa7975c09701692b6c57c20a" rel="nofollow" data-download="{&quot;attachment_id&quot;:70622269,&quot;asset_id&quot;:54089416,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/70622269/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="169826501" href="https://independent.academia.edu/SanjayKumar2446">Sanjay Kumar</a><script data-card-contents-for-user="169826501" type="text/json">{"id":169826501,"first_name":"Sanjay","last_name":"Kumar","domain_name":"independent","page_name":"SanjayKumar2446","display_name":"Sanjay Kumar","profile_url":"https://independent.academia.edu/SanjayKumar2446?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_54089416 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="54089416"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 54089416, container: ".js-paper-rank-work_54089416", }); 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Substance","url":"https://www.academia.edu/Documents/in/Thiobarbituric_Acid_Reactive_Substance?f_ri=1134083"},{"id":1438730,"name":"Creatinine","url":"https://www.academia.edu/Documents/in/Creatinine?f_ri=1134083"},{"id":1452649,"name":"Fasting Blood Glucose","url":"https://www.academia.edu/Documents/in/Fasting_Blood_Glucose?f_ri=1134083"},{"id":1850893,"name":"Serum lipids","url":"https://www.academia.edu/Documents/in/Serum_lipids?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_1502590" data-work_id="1502590" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/1502590/Inhibitory_effect_of_mitragynine_an_alkaloid_with_analgesic_effect_from_thai_medicinal_plant_Mitragyna_speciosa_on_electrically_stimulated_contraction_of_isolated_guinea_pig_ileum_through_the_opioid_receptor">Inhibitory effect of mitragynine, an alkaloid with analgesic effect from thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Effect of mitragynine, an indole alkaloid isolated from Thai medicinal plant kratom (Mitragyna speciosa), on electrically stimulated contraction was studied in the guinea-pig ileum. Mitragynine (1 nM - 3 μM) inhibited the ileum... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_1502590" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Effect of mitragynine, an indole alkaloid isolated from Thai medicinal plant kratom (Mitragyna speciosa), on electrically stimulated contraction was studied in the guinea-pig ileum. Mitragynine (1 nM - 3 μM) inhibited the ileum contraction elicited by electrical stimulation, and its pD2 value was 6.91 ± 0.04 (n = 5). Morphine (1 nM − 1 μM) also inhibited the electrically stimulated contraction in a concentration-dependent manner (pD2 7.68 ± 0.11; n = 5). Mitragynine was 10 fold less potent than morphine. Mitragynine (3–10 μM) did not show any effect on the smooth muscle contraction induced by acetylcholine or histamine. Naloxone (10–300 nM) reversed the inhibitory effect of mitragynine on electrically stimulated contraction. Furthermore, naloxone showed a shift of concentration-response curve of mitragynine to the right. There was no significant difference in the affinity of naloxone (i.e. pA2) in the presence of mitragynine or morphine. Mitragynine (3–10 μM) inhibited the naloxone-precipitated withdrawal contraction following a brief (5 min) exposure of the ileum to morphine. Tetrodotoxin (1 μM) and atropine (1 μM) inhibited the withdrawal contraction. The present results suggest that mitragynine inhibits the electrically stimulated contraction of guinea-pig ileum through the opioid receptor.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/1502590" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0943031a667f43eb92cc3d7668cc61d3" rel="nofollow" data-download="{&quot;attachment_id&quot;:50947235,&quot;asset_id&quot;:1502590,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50947235/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="1471748" href="https://uniraj.academia.edu/SapanaKhandelwal">Sapana Khandelwal</a><script data-card-contents-for-user="1471748" type="text/json">{"id":1471748,"first_name":"Sapana","last_name":"Khandelwal","domain_name":"uniraj","page_name":"SapanaKhandelwal","display_name":"Sapana Khandelwal","profile_url":"https://uniraj.academia.edu/SapanaKhandelwal?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_1502590 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="1502590"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 1502590, container: ".js-paper-rank-work_1502590", }); 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Mitragynine (1 nM - 3 μM) inhibited the ileum contraction elicited by electrical stimulation, and its pD2 value was 6.91 ± 0.04 (n = 5). Morphine (1 nM − 1 μM) also inhibited the electrically stimulated contraction in a concentration-dependent manner (pD2 7.68 ± 0.11; n = 5). Mitragynine was 10 fold less potent than morphine. Mitragynine (3–10 μM) did not show any effect on the smooth muscle contraction induced by acetylcholine or histamine. Naloxone (10–300 nM) reversed the inhibitory effect of mitragynine on electrically stimulated contraction. Furthermore, naloxone showed a shift of concentration-response curve of mitragynine to the right. There was no significant difference in the affinity of naloxone (i.e. pA2) in the presence of mitragynine or morphine. Mitragynine (3–10 μM) inhibited the naloxone-precipitated withdrawal contraction following a brief (5 min) exposure of the ileum to morphine. Tetrodotoxin (1 μM) and atropine (1 μM) inhibited the withdrawal contraction. The present results suggest that mitragynine inhibits the electrically stimulated contraction of guinea-pig ileum through the opioid receptor.","downloadable_attachments":[{"id":50947235,"asset_id":1502590,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":1471748,"first_name":"Sapana","last_name":"Khandelwal","domain_name":"uniraj","page_name":"SapanaKhandelwal","display_name":"Sapana Khandelwal","profile_url":"https://uniraj.academia.edu/SapanaKhandelwal?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":8014,"name":"Life Sciences","url":"https://www.academia.edu/Documents/in/Life_Sciences?f_ri=1134083","nofollow":false},{"id":51569,"name":"Histamine","url":"https://www.academia.edu/Documents/in/Histamine?f_ri=1134083","nofollow":false},{"id":65171,"name":"Smooth muscle","url":"https://www.academia.edu/Documents/in/Smooth_muscle?f_ri=1134083","nofollow":false},{"id":159958,"name":"Acetylcholine","url":"https://www.academia.edu/Documents/in/Acetylcholine?f_ri=1134083","nofollow":false},{"id":218374,"name":"Morphine","url":"https://www.academia.edu/Documents/in/Morphine?f_ri=1134083"},{"id":485556,"name":"Guinea Pig","url":"https://www.academia.edu/Documents/in/Guinea_Pig?f_ri=1134083"},{"id":556021,"name":"Muscle contraction","url":"https://www.academia.edu/Documents/in/Muscle_contraction?f_ri=1134083"},{"id":956370,"name":"Opioid Receptor","url":"https://www.academia.edu/Documents/in/Opioid_Receptor?f_ri=1134083"},{"id":1128472,"name":"Naloxone","url":"https://www.academia.edu/Documents/in/Naloxone?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1445770,"name":"Analgesics","url":"https://www.academia.edu/Documents/in/Analgesics?f_ri=1134083"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology?f_ri=1134083"},{"id":1901112,"name":"Ileum","url":"https://www.academia.edu/Documents/in/Ileum?f_ri=1134083"},{"id":2085017,"name":"Clonidine","url":"https://www.academia.edu/Documents/in/Clonidine?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_72529244" data-work_id="72529244" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/72529244/In_vitro_antimicrobial_activity_of_ten_medicinal_plants_against_clinical_isolates_of_oral_cancer_cases">In vitro antimicrobial activity of ten medicinal plants against clinical isolates of oral cancer cases</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background Suppression of immune system in treated cancer patients may lead to secondary infections that obviate the need of antibiotics. In the present study, an attempt was made to understand the occurrence of secondary infections in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72529244" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background Suppression of immune system in treated cancer patients may lead to secondary infections that obviate the need of antibiotics. In the present study, an attempt was made to understand the occurrence of secondary infections in immuno-suppressed patients along with herbal control of these infections with the following objectives to: (a) isolate the microbial species from the treated oral cancer patients along with the estimation of absolute neutrophile counts of patients (b) assess the in vitro antimicrobial activity medicinal plants against the above clinical isolates. Methods Blood and oral swab cultures were taken from 40 oral cancer patients undergoing treatment in the radiotherapy unit of Regional Cancer Institute, Pt. B.D.S. Health University, Rohtak, Haryana. Clinical isolates were identified by following general microbiological, staining and biochemical methods. The absolute neutrophile counts were done by following the standard methods. The medicinal plants selected...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72529244" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0f436edaa9816b90c178f059c62f7c49" rel="nofollow" data-download="{&quot;attachment_id&quot;:81421577,&quot;asset_id&quot;:72529244,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81421577/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="215973806" href="https://independent.academia.edu/VivekKaushal16">Vivek Kaushal</a><script data-card-contents-for-user="215973806" type="text/json">{"id":215973806,"first_name":"Vivek","last_name":"Kaushal","domain_name":"independent","page_name":"VivekKaushal16","display_name":"Vivek Kaushal","profile_url":"https://independent.academia.edu/VivekKaushal16?f_ri=1134083","photo":"https://0.academia-photos.com/215973806/74457169/62953772/s65_vivek.kaushal.jpeg"}</script></span></span></li><li class="js-paper-rank-work_72529244 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72529244"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72529244, container: ".js-paper-rank-work_72529244", }); 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$(".js-view-count[data-work-id=72529244]").text(description); $(".js-view-count-work_72529244").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_72529244").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="72529244"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">19</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a>,&nbsp;<script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17272" href="https://www.academia.edu/Documents/in/Fungi">Fungi</a>,&nbsp;<script data-card-contents-for-ri="17272" type="text/json">{"id":17272,"name":"Fungi","url":"https://www.academia.edu/Documents/in/Fungi?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="83128" href="https://www.academia.edu/Documents/in/Escherichia_coli">Escherichia coli</a><script data-card-contents-for-ri="83128" type="text/json">{"id":83128,"name":"Escherichia coli","url":"https://www.academia.edu/Documents/in/Escherichia_coli?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72529244]'), work: {"id":72529244,"title":"In vitro antimicrobial activity of ten medicinal plants against clinical isolates of oral cancer cases","created_at":"2022-02-27T02:26:04.071-08:00","url":"https://www.academia.edu/72529244/In_vitro_antimicrobial_activity_of_ten_medicinal_plants_against_clinical_isolates_of_oral_cancer_cases?f_ri=1134083","dom_id":"work_72529244","summary":"Background Suppression of immune system in treated cancer patients may lead to secondary infections that obviate the need of antibiotics. In the present study, an attempt was made to understand the occurrence of secondary infections in immuno-suppressed patients along with herbal control of these infections with the following objectives to: (a) isolate the microbial species from the treated oral cancer patients along with the estimation of absolute neutrophile counts of patients (b) assess the in vitro antimicrobial activity medicinal plants against the above clinical isolates. Methods Blood and oral swab cultures were taken from 40 oral cancer patients undergoing treatment in the radiotherapy unit of Regional Cancer Institute, Pt. B.D.S. Health University, Rohtak, Haryana. Clinical isolates were identified by following general microbiological, staining and biochemical methods. The absolute neutrophile counts were done by following the standard methods. The medicinal plants selected...","downloadable_attachments":[{"id":81421577,"asset_id":72529244,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":215973806,"first_name":"Vivek","last_name":"Kaushal","domain_name":"independent","page_name":"VivekKaushal16","display_name":"Vivek Kaushal","profile_url":"https://independent.academia.edu/VivekKaushal16?f_ri=1134083","photo":"https://0.academia-photos.com/215973806/74457169/62953772/s65_vivek.kaushal.jpeg"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=1134083","nofollow":false},{"id":17272,"name":"Fungi","url":"https://www.academia.edu/Documents/in/Fungi?f_ri=1134083","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1134083","nofollow":false},{"id":83128,"name":"Escherichia coli","url":"https://www.academia.edu/Documents/in/Escherichia_coli?f_ri=1134083","nofollow":false},{"id":111007,"name":"Antimicrobial activity","url":"https://www.academia.edu/Documents/in/Antimicrobial_activity?f_ri=1134083"},{"id":113903,"name":"Bacteria","url":"https://www.academia.edu/Documents/in/Bacteria?f_ri=1134083"},{"id":131573,"name":"Candida albicans","url":"https://www.academia.edu/Documents/in/Candida_albicans?f_ri=1134083"},{"id":215633,"name":"Aspergillus fumigatus","url":"https://www.academia.edu/Documents/in/Aspergillus_fumigatus-1?f_ri=1134083"},{"id":216311,"name":"Fungal Pathogens","url":"https://www.academia.edu/Documents/in/Fungal_Pathogens?f_ri=1134083"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=1134083"},{"id":324154,"name":"Immune system","url":"https://www.academia.edu/Documents/in/Immune_system?f_ri=1134083"},{"id":532278,"name":"Cancer Patient","url":"https://www.academia.edu/Documents/in/Cancer_Patient?f_ri=1134083"},{"id":561014,"name":"Microbial Sensitivity Tests","url":"https://www.academia.edu/Documents/in/Microbial_Sensitivity_Tests?f_ri=1134083"},{"id":587528,"name":"Bacterial infections","url":"https://www.academia.edu/Documents/in/Bacterial_infections?f_ri=1134083"},{"id":749302,"name":"Indexation","url":"https://www.academia.edu/Documents/in/Indexation?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":2037499,"name":"Klebsiella pneumoniae","url":"https://www.academia.edu/Documents/in/Klebsiella_pneumoniae?f_ri=1134083"},{"id":3360152,"name":"Absolute Neutrophil Count","url":"https://www.academia.edu/Documents/in/Absolute_Neutrophil_Count?f_ri=1134083"},{"id":3969947,"name":"Antimicrobial agent","url":"https://www.academia.edu/Documents/in/Antimicrobial_agent?f_ri=1134083"}]}, }) } 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Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083"},{"id":19870,"name":"Research","url":"https://www.academia.edu/Documents/in/Research?f_ri=1134083"},{"id":411275,"name":"Ethical Issues","url":"https://www.academia.edu/Documents/in/Ethical_Issues?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_75933615 coauthored" data-work_id="75933615" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/75933615/PAL_Gene_Activity_and_Rosmarinic_Acid_Production_in_Rosemary_Genotypes">PAL Gene Activity and Rosmarinic Acid Production in Rosemary Genotypes</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Phenylalanine ammonia-lyase (PAL) catalyzes the biosynthesis of rosmarinic acid (RA) in Rosmarinus officinalis. Increases in RA content in plant tissue in vitro coincided with increases in PAL activity. The activity of the gene... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_75933615" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Phenylalanine ammonia-lyase (PAL) catalyzes the biosynthesis of rosmarinic acid (RA) in Rosmarinus officinalis. Increases in RA content in plant tissue in vitro coincided with increases in PAL activity. The activity of the gene responsible for the production of the PAL enzyme in five rosemary genotypes was investigated to better understand the accumulation of RA. The expression of the PAL gene</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/75933615" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="debc60c131e51ac3dc589c7abb1878e0" rel="nofollow" data-download="{&quot;attachment_id&quot;:84056468,&quot;asset_id&quot;:75933615,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/84056468/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41579730" href="https://independent.academia.edu/ElnaggarH">Hany Elnaggar</a><script data-card-contents-for-user="41579730" type="text/json">{"id":41579730,"first_name":"Hany","last_name":"Elnaggar","domain_name":"independent","page_name":"ElnaggarH","display_name":"Hany Elnaggar","profile_url":"https://independent.academia.edu/ElnaggarH?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-75933615">+1</span><div class="hidden js-additional-users-75933615"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/PaulRead9">Paul Read</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-75933615'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-75933615').html(); 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Increases in RA content in plant tissue in vitro coincided with increases in PAL activity. The activity of the gene responsible for the production of the PAL enzyme in five rosemary genotypes was investigated to better understand the accumulation of RA. The expression of the PAL gene","downloadable_attachments":[{"id":84056468,"asset_id":75933615,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41579730,"first_name":"Hany","last_name":"Elnaggar","domain_name":"independent","page_name":"ElnaggarH","display_name":"Hany Elnaggar","profile_url":"https://independent.academia.edu/ElnaggarH?f_ri=1134083","photo":"/images/s65_no_pic.png"},{"id":221473638,"first_name":"Paul","last_name":"Read","domain_name":"independent","page_name":"PaulRead9","display_name":"Paul Read","profile_url":"https://independent.academia.edu/PaulRead9?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=1134083","nofollow":false},{"id":27784,"name":"Gene expression","url":"https://www.academia.edu/Documents/in/Gene_expression?f_ri=1134083","nofollow":false},{"id":181936,"name":"Gene","url":"https://www.academia.edu/Documents/in/Gene?f_ri=1134083","nofollow":false},{"id":231661,"name":"Enzyme","url":"https://www.academia.edu/Documents/in/Enzyme?f_ri=1134083","nofollow":false},{"id":316015,"name":"Gen","url":"https://www.academia.edu/Documents/in/Gen?f_ri=1134083"},{"id":372410,"name":"Genotype","url":"https://www.academia.edu/Documents/in/Genotype?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1493934,"name":"Phenylalanine ammonia lyase","url":"https://www.academia.edu/Documents/in/Phenylalanine_ammonia_lyase?f_ri=1134083"},{"id":1631701,"name":"Rosmarinic Acid","url":"https://www.academia.edu/Documents/in/Rosmarinic_Acid?f_ri=1134083"},{"id":1943314,"name":"Tissue Specificity","url":"https://www.academia.edu/Documents/in/Tissue_Specificity?f_ri=1134083"},{"id":2674671,"name":"Horticultural production","url":"https://www.academia.edu/Documents/in/Horticultural_production?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_75281651" data-work_id="75281651" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/75281651/WILD_PLANTS_USED_AS_MEDICINAL_PURPOSE_in_YALOVA_NORTHWEST_TURKEY_">WILD PLANTS USED AS MEDICINAL PURPOSE in YALOVA (NORTHWEST TURKEY)</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In this study, medicinal uses and methods of administration of 45 wild plant taxa belonging to 27 families in Yalova are documented. The plant specimens were collected with informants. During the field works all the settlements (58... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_75281651" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In this study, medicinal uses and methods of administration of 45 wild plant taxa belonging to 27 families in Yalova are documented. The plant specimens were collected with informants. During the field works all the settlements (58 villages) were visited. The information was recorded and the collected plants were identified and prepared voucher specimens were kept in the Herbarium of Istanbul University Faculty of Pharmacy (ISTE). Özet Bu çalismada, Yalova&amp;#39;da tibbi amaçli kullanilan 27 familyaya ait, 45 dogal taksonun kullanilis nedenleri, uygulanis sekilleri arastirilmis ve kaydedilmistir. Bitkiler bilgi veren kisiler ile birlikte toplanmistir. Arazi çalismalari sirasinda bütün yerlesim yerlerine (58 köy) gidilmistir. Bilgiler kaydedilmis, toplanan bitkiler teshis edilmis ve hazirlanan herbaryum örnekleri Istanbul Üniversitesi Eczacilik Fakültesi Herbaryumu (ISTE)&amp;#39;nda saklanmistir.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/75281651" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9c3d0d7b98f3307ec398680d99897127" rel="nofollow" data-download="{&quot;attachment_id&quot;:83113505,&quot;asset_id&quot;:75281651,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/83113505/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="187759" href="https://istanbul.academia.edu/Neriman%C3%96zhatay">Neriman Özhatay</a><script data-card-contents-for-user="187759" type="text/json">{"id":187759,"first_name":"Neriman","last_name":"Özhatay","domain_name":"istanbul","page_name":"NerimanÖzhatay","display_name":"Neriman Özhatay","profile_url":"https://istanbul.academia.edu/Neriman%C3%96zhatay?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_75281651 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="75281651"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 75281651, container: ".js-paper-rank-work_75281651", }); 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$(".js-view-count[data-work-id=75281651]").text(description); $(".js-view-count-work_75281651").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_75281651").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="75281651"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">5</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="261" href="https://www.academia.edu/Documents/in/Geography">Geography</a>,&nbsp;<script data-card-contents-for-ri="261" type="text/json">{"id":261,"name":"Geography","url":"https://www.academia.edu/Documents/in/Geography?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3867" href="https://www.academia.edu/Documents/in/Folk_Medicine">Folk Medicine</a>,&nbsp;<script data-card-contents-for-ri="3867" type="text/json">{"id":3867,"name":"Folk Medicine","url":"https://www.academia.edu/Documents/in/Folk_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="15019" href="https://www.academia.edu/Documents/in/Medicinal_Plants">Medicinal Plants</a>,&nbsp;<script data-card-contents-for-ri="15019" type="text/json">{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="739883" href="https://www.academia.edu/Documents/in/Yalova">Yalova</a><script data-card-contents-for-ri="739883" type="text/json">{"id":739883,"name":"Yalova","url":"https://www.academia.edu/Documents/in/Yalova?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=75281651]'), work: {"id":75281651,"title":"WILD PLANTS USED AS MEDICINAL PURPOSE in YALOVA (NORTHWEST TURKEY)","created_at":"2022-04-02T23:11:24.303-07:00","url":"https://www.academia.edu/75281651/WILD_PLANTS_USED_AS_MEDICINAL_PURPOSE_in_YALOVA_NORTHWEST_TURKEY_?f_ri=1134083","dom_id":"work_75281651","summary":"In this study, medicinal uses and methods of administration of 45 wild plant taxa belonging to 27 families in Yalova are documented. The plant specimens were collected with informants. During the field works all the settlements (58 villages) were visited. The information was recorded and the collected plants were identified and prepared voucher specimens were kept in the Herbarium of Istanbul University Faculty of Pharmacy (ISTE). Özet Bu çalismada, Yalova\u0026#39;da tibbi amaçli kullanilan 27 familyaya ait, 45 dogal taksonun kullanilis nedenleri, uygulanis sekilleri arastirilmis ve kaydedilmistir. Bitkiler bilgi veren kisiler ile birlikte toplanmistir. Arazi çalismalari sirasinda bütün yerlesim yerlerine (58 köy) gidilmistir. Bilgiler kaydedilmis, toplanan bitkiler teshis edilmis ve hazirlanan herbaryum örnekleri Istanbul Üniversitesi Eczacilik Fakültesi Herbaryumu (ISTE)\u0026#39;nda saklanmistir.","downloadable_attachments":[{"id":83113505,"asset_id":75281651,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":187759,"first_name":"Neriman","last_name":"Özhatay","domain_name":"istanbul","page_name":"NerimanÖzhatay","display_name":"Neriman Özhatay","profile_url":"https://istanbul.academia.edu/Neriman%C3%96zhatay?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":261,"name":"Geography","url":"https://www.academia.edu/Documents/in/Geography?f_ri=1134083","nofollow":false},{"id":3867,"name":"Folk Medicine","url":"https://www.academia.edu/Documents/in/Folk_Medicine?f_ri=1134083","nofollow":false},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083","nofollow":false},{"id":739883,"name":"Yalova","url":"https://www.academia.edu/Documents/in/Yalova?f_ri=1134083","nofollow":false},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_58569997" data-work_id="58569997" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/58569997/Phytochemistry_pharmacology_and_biotechnology_of_Withania_somnifera_and_Withania_coagulans_A_review">Phytochemistry, pharmacology, and biotechnology of Withania somnifera and Withania coagulans: A review</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/58569997" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bd2579b845c74353c2a7d30f372c2ffb" rel="nofollow" data-download="{&quot;attachment_id&quot;:72918741,&quot;asset_id&quot;:58569997,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/72918741/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="48068736" href="https://independent.academia.edu/SumitaKachhwaha">Sumita Kachhwaha</a><script data-card-contents-for-user="48068736" type="text/json">{"id":48068736,"first_name":"Sumita","last_name":"Kachhwaha","domain_name":"independent","page_name":"SumitaKachhwaha","display_name":"Sumita Kachhwaha","profile_url":"https://independent.academia.edu/SumitaKachhwaha?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_58569997 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="58569997"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 58569997, container: ".js-paper-rank-work_58569997", }); 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Histological studies... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_5585763" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Shoot buds emerged from intact leaves while still attached to plants after 60 days, without subculturing, on Murashige and Skoog (MS) medium containing 10.0 μM 6-benzylaminopurine and 5.0 μM indole-3-butyric acid. Histological studies revealed the emergence of shoot buds directly from the leaf surface without an intervening callus phase. Regenerated plantlets were successfully transferred to the greenhouse after rooting in plant growth regulator-free MS medium. The survival percentage of transferred plants was very low. However, pretreatment of the plants at low temperature (15±2°C) for 10 days before transfer to greenhouse conditions increased the survival percentage. The increased survival was supported by an increased number of vascular bundles, leaf thickness, net rate of photosynthesis (PN), stomatal conductance (gs) and density (SD). The direct regeneration method from intact leaves of R. emodi will reduce the cost, time and labor required and hence can be successfully employed for faster in vitro multiplication and conservation of this endangered and medicinally important plant species.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/5585763" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8de70c2084db0232ba033a12598150f2" rel="nofollow" data-download="{&quot;attachment_id&quot;:49229005,&quot;asset_id&quot;:5585763,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49229005/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="7964378" href="https://independent.academia.edu/SurenderVats">Surender Vats</a><script data-card-contents-for-user="7964378" type="text/json">{"id":7964378,"first_name":"Surender","last_name":"Vats","domain_name":"independent","page_name":"SurenderVats","display_name":"Surender Vats","profile_url":"https://independent.academia.edu/SurenderVats?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_5585763 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="5585763"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 5585763, container: ".js-paper-rank-work_5585763", }); 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Histological studies revealed the emergence of shoot buds directly from the leaf surface without an intervening callus phase. Regenerated plantlets were successfully transferred to the greenhouse after rooting in plant growth regulator-free MS medium. The survival percentage of transferred plants was very low. However, pretreatment of the plants at low temperature (15±2°C) for 10 days before transfer to greenhouse conditions increased the survival percentage. The increased survival was supported by an increased number of vascular bundles, leaf thickness, net rate of photosynthesis (PN), stomatal conductance (gs) and density (SD). The direct regeneration method from intact leaves of R. emodi will reduce the cost, time and labor required and hence can be successfully employed for faster in vitro multiplication and conservation of this endangered and medicinally important plant species.","downloadable_attachments":[{"id":49229005,"asset_id":5585763,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":7964378,"first_name":"Surender","last_name":"Vats","domain_name":"independent","page_name":"SurenderVats","display_name":"Surender Vats","profile_url":"https://independent.academia.edu/SurenderVats?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=1134083","nofollow":false},{"id":923,"name":"Technology","url":"https://www.academia.edu/Documents/in/Technology?f_ri=1134083","nofollow":false},{"id":1134083,"name":"Medicinal 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href="https://www.academia.edu/24767531/Spasmolytic_action_of_Lepechinia_caulescens_is_through_calcium_channel_blockade_and_NO_release">Spasmolytic action of Lepechinia caulescens is through calcium channel blockade and NO release</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The present study was undertaken to elucidate the mode of action of methanol extract from aerial parts of L. caulescens (TC-MELc) as spasmolytic agent on in vitro rat ileum test, and investigate the possible antibacterial activity of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_24767531" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The present study was undertaken to elucidate the mode of action of methanol extract from aerial parts of L. caulescens (TC-MELc) as spasmolytic agent on in vitro rat ileum test, and investigate the possible antibacterial activity of different extracts from the plant. TC-MELc ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/24767531" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b042e27a5cb4edf711fa50faf41a1e6a" rel="nofollow" data-download="{&quot;attachment_id&quot;:45096549,&quot;asset_id&quot;:24767531,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45096549/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32527703" href="https://independent.academia.edu/SamuelEstradaSoto">Samuel Estrada-Soto</a><script data-card-contents-for-user="32527703" type="text/json">{"id":32527703,"first_name":"Samuel","last_name":"Estrada-Soto","domain_name":"independent","page_name":"SamuelEstradaSoto","display_name":"Samuel Estrada-Soto","profile_url":"https://independent.academia.edu/SamuelEstradaSoto?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_24767531 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="24767531"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 24767531, container: ".js-paper-rank-work_24767531", }); 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Adams, a traditional antimalarial medicinal plant, with artemisinin against Plasmodium falciparum","created_at":"2015-11-15T22:44:36.787-08:00","url":"https://www.academia.edu/18412187/In_vitro_interactions_of_Aspilia_africana_Pers_C_D_Adams_a_traditional_antimalarial_medicinal_plant_with_artemisinin_against_Plasmodium_falciparum?f_ri=1134083","dom_id":"work_18412187","summary":null,"downloadable_attachments":[{"id":40050184,"asset_id":18412187,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38421189,"first_name":"Peter","last_name":"Folb","domain_name":"independent","page_name":"PeterFolb","display_name":"Peter Folb","profile_url":"https://independent.academia.edu/PeterFolb?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":11558,"name":"Drug interactions","url":"https://www.academia.edu/Documents/in/Drug_interactions?f_ri=1134083","nofollow":false},{"id":14032,"name":"Ethnopharmacology","url":"https://www.academia.edu/Documents/in/Ethnopharmacology?f_ri=1134083"},{"id":43838,"name":"India","url":"https://www.academia.edu/Documents/in/India?f_ri=1134083"},{"id":194060,"name":"Asteraceae","url":"https://www.academia.edu/Documents/in/Asteraceae?f_ri=1134083"},{"id":239046,"name":"Sesquiterpenes","url":"https://www.academia.edu/Documents/in/Sesquiterpenes?f_ri=1134083"},{"id":354056,"name":"Plant extracts","url":"https://www.academia.edu/Documents/in/Plant_extracts?f_ri=1134083"},{"id":454230,"name":"Plasmodium falciparum","url":"https://www.academia.edu/Documents/in/Plasmodium_falciparum?f_ri=1134083"},{"id":454707,"name":"Antimalarials","url":"https://www.academia.edu/Documents/in/Antimalarials?f_ri=1134083"},{"id":982534,"name":"Erythrocytes","url":"https://www.academia.edu/Documents/in/Erythrocytes?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16771998" data-work_id="16771998" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16771998/Toxicological_evaluation_of_a_tea_from_leaves_of_Vernonia_condensata">Toxicological evaluation of a tea from leaves of Vernonia condensata</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Teas of Vernonia condensata Baker (Asteraceae) are widely used in Brazil for gastro-intestinal disorders and to treat several other diseases. In this study, we evaluated the acute toxicity, embryotoxicity and mutagenicity of a lyophilized... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16771998" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Teas of Vernonia condensata Baker (Asteraceae) are widely used in Brazil for gastro-intestinal disorders and to treat several other diseases. In this study, we evaluated the acute toxicity, embryotoxicity and mutagenicity of a lyophilized aqueous extract (LAE) from V. condensata leaves. Single doses of LAE, up to 5000 mg/kg body weight, were given orally or intraperitoneally to male and female Swiss albino mice. No toxicity was observed after oral administration. The &amp;amp;quot;Approximate Lethal Dose&amp;amp;quot; after intraperitoneal injections was 3400 mg/kg for males and 5000 mg/kg for females. Embryotoxicity was investigated in Han:NMRI mice. LAE (0, 500 and 2000 mg/kg/day) was given by gavage on days 10, 11 and 12, and dams were submitted to caesarean sections on day 18 of pregnancy. Fetuses were weighed, examined for externally visible malformations, and evaluated for skeletal anomalies. Except for a slight reduction of fetal body weight accompanied by signs of delayed ossification at the highest dose, no other embryotoxic effect was noted in the exposed offspring. LAE-induced mutagenicity was evaluated in the Salmonella/microsome assay without and with S9 mixture. LAE, tested up to 5000 microg/plate, was not mutagenic to tester strains TA97a, TA98 and TA100. Results therefore suggest that V. condensata aqueous extracts present low acute toxicity and pose neither teratogenic nor mutagenic risks.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16771998" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="806c030c1c167ba5cc98a6e7fd868851" rel="nofollow" data-download="{&quot;attachment_id&quot;:42401159,&quot;asset_id&quot;:16771998,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42401159/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36200924" href="https://independent.academia.edu/IbrahimChahoud">Ibrahim Chahoud</a><script data-card-contents-for-user="36200924" type="text/json">{"id":36200924,"first_name":"Ibrahim","last_name":"Chahoud","domain_name":"independent","page_name":"IbrahimChahoud","display_name":"Ibrahim Chahoud","profile_url":"https://independent.academia.edu/IbrahimChahoud?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_16771998 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16771998"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16771998, container: ".js-paper-rank-work_16771998", }); 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$(".js-view-count[data-work-id=16771998]").text(description); $(".js-view-count-work_16771998").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_16771998").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="16771998"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">18</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4083" href="https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine">Complementary and Alternative Medicine</a>,&nbsp;<script data-card-contents-for-ri="4083" type="text/json">{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a>,&nbsp;<script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14032" href="https://www.academia.edu/Documents/in/Ethnopharmacology">Ethnopharmacology</a>,&nbsp;<script data-card-contents-for-ri="14032" type="text/json">{"id":14032,"name":"Ethnopharmacology","url":"https://www.academia.edu/Documents/in/Ethnopharmacology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="15019" href="https://www.academia.edu/Documents/in/Medicinal_Plants">Medicinal Plants</a><script data-card-contents-for-ri="15019" type="text/json">{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=16771998]'), work: {"id":16771998,"title":"Toxicological evaluation of a tea from leaves of Vernonia condensata","created_at":"2015-10-14T03:01:26.871-07:00","url":"https://www.academia.edu/16771998/Toxicological_evaluation_of_a_tea_from_leaves_of_Vernonia_condensata?f_ri=1134083","dom_id":"work_16771998","summary":"Teas of Vernonia condensata Baker (Asteraceae) are widely used in Brazil for gastro-intestinal disorders and to treat several other diseases. In this study, we evaluated the acute toxicity, embryotoxicity and mutagenicity of a lyophilized aqueous extract (LAE) from V. condensata leaves. Single doses of LAE, up to 5000 mg/kg body weight, were given orally or intraperitoneally to male and female Swiss albino mice. No toxicity was observed after oral administration. The \u0026amp;quot;Approximate Lethal Dose\u0026amp;quot; after intraperitoneal injections was 3400 mg/kg for males and 5000 mg/kg for females. Embryotoxicity was investigated in Han:NMRI mice. LAE (0, 500 and 2000 mg/kg/day) was given by gavage on days 10, 11 and 12, and dams were submitted to caesarean sections on day 18 of pregnancy. Fetuses were weighed, examined for externally visible malformations, and evaluated for skeletal anomalies. Except for a slight reduction of fetal body weight accompanied by signs of delayed ossification at the highest dose, no other embryotoxic effect was noted in the exposed offspring. LAE-induced mutagenicity was evaluated in the Salmonella/microsome assay without and with S9 mixture. LAE, tested up to 5000 microg/plate, was not mutagenic to tester strains TA97a, TA98 and TA100. Results therefore suggest that V. condensata aqueous extracts present low acute toxicity and pose neither teratogenic nor mutagenic risks.","downloadable_attachments":[{"id":42401159,"asset_id":16771998,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36200924,"first_name":"Ibrahim","last_name":"Chahoud","domain_name":"independent","page_name":"IbrahimChahoud","display_name":"Ibrahim Chahoud","profile_url":"https://independent.academia.edu/IbrahimChahoud?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":14032,"name":"Ethnopharmacology","url":"https://www.academia.edu/Documents/in/Ethnopharmacology?f_ri=1134083","nofollow":false},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083","nofollow":false},{"id":58429,"name":"Caesarean Section","url":"https://www.academia.edu/Documents/in/Caesarean_Section?f_ri=1134083"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=1134083"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=1134083"},{"id":102637,"name":"Salmonella Typhimurium","url":"https://www.academia.edu/Documents/in/Salmonella_Typhimurium?f_ri=1134083"},{"id":194060,"name":"Asteraceae","url":"https://www.academia.edu/Documents/in/Asteraceae?f_ri=1134083"},{"id":354056,"name":"Plant extracts","url":"https://www.academia.edu/Documents/in/Plant_extracts?f_ri=1134083"},{"id":564878,"name":"Body Weight","url":"https://www.academia.edu/Documents/in/Body_Weight?f_ri=1134083"},{"id":725563,"name":"Teratogens","url":"https://www.academia.edu/Documents/in/Teratogens?f_ri=1134083"},{"id":980394,"name":"Acute Toxicity","url":"https://www.academia.edu/Documents/in/Acute_Toxicity?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1141692,"name":"Weight Gain","url":"https://www.academia.edu/Documents/in/Weight_Gain?f_ri=1134083"},{"id":1162913,"name":"Mutagens","url":"https://www.academia.edu/Documents/in/Mutagens?f_ri=1134083"},{"id":1174953,"name":"Aqueous Extract","url":"https://www.academia.edu/Documents/in/Aqueous_Extract?f_ri=1134083"},{"id":1905343,"name":"Plant Leaves","url":"https://www.academia.edu/Documents/in/Plant_Leaves?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_43994410" data-work_id="43994410" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/43994410/Annals_of_Phytomedicine">Annals of Phytomedicine</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Ajuga turkestanica (Rgl.) Brig (Lamiaceae) is a medicinal, herbaceous flowering species which has been traditionally used in Uzbekistan for cure of various human diseases like, heart disease, muscle aches and stomach problems. This plant... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_43994410" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Ajuga turkestanica (Rgl.) Brig (Lamiaceae) is a medicinal, herbaceous flowering species which has been traditionally used in Uzbekistan for cure of various human diseases like, heart disease, muscle aches and stomach problems. This plant possesses diverse pharmacological activities, antibacterial activity, hypoglycemic activity, hypolipidemic action, anabolic activity: growth promotion, increase in protein synthesis in skeletal muscle cells, hepatoprotection activities. Several compounds have been isolated from A. turkestanica, which display a wide spectrum of biological and pharmacological activities. This review provides scientific information on the biologically active substances of the medicinal plant A. turkestanica, their structure, pharmacology, and applications in pharmaceuticals and medicine.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/43994410" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="967996f9316fb426721d188dfb9bdec4" rel="nofollow" data-download="{&quot;attachment_id&quot;:64326214,&quot;asset_id&quot;:43994410,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/64326214/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="55442882" href="https://independent.academia.edu/JabborovaDilfuza">Dilfuza Jabborova</a><script data-card-contents-for-user="55442882" type="text/json">{"id":55442882,"first_name":"Dilfuza","last_name":"Jabborova","domain_name":"independent","page_name":"JabborovaDilfuza","display_name":"Dilfuza Jabborova","profile_url":"https://independent.academia.edu/JabborovaDilfuza?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_43994410 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="43994410"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 43994410, container: ".js-paper-rank-work_43994410", }); });</script></li><li class="js-percentile-work_43994410 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 43994410; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_43994410"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_43994410 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="43994410"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 43994410; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=43994410]").text(description); $(".js-view-count-work_43994410").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_43994410").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="43994410"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i></div><span class="InlineList-item-text u-textTruncate u-pl6x"><a class="InlineList-item-text" data-has-card-for-ri="1134083" href="https://www.academia.edu/Documents/in/Medicinal_Plant">Medicinal Plant</a><script data-card-contents-for-ri="1134083" type="text/json">{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (false) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=43994410]'), work: {"id":43994410,"title":"Annals of Phytomedicine","created_at":"2020-09-01T04:58:36.410-07:00","url":"https://www.academia.edu/43994410/Annals_of_Phytomedicine?f_ri=1134083","dom_id":"work_43994410","summary":"Ajuga turkestanica (Rgl.) Brig (Lamiaceae) is a medicinal, herbaceous flowering species which has been traditionally used in Uzbekistan for cure of various human diseases like, heart disease, muscle aches and stomach problems. This plant possesses diverse pharmacological activities, antibacterial activity, hypoglycemic activity, hypolipidemic action, anabolic activity: growth promotion, increase in protein synthesis in skeletal muscle cells, hepatoprotection activities. Several compounds have been isolated from A. turkestanica, which display a wide spectrum of biological and pharmacological activities. 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itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/30381175/Comparative_antimicrobial_activity_of_Acacia_nilotica_L_leaves_extracts_against_Pathogenic_Bacteria_and_Fungi">Comparative antimicrobial activity of Acacia nilotica L. leaves extracts against Pathogenic Bacteria and Fungi</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The comparative in vitro antimicrobial activity of ethanol and chloroform leaves extracts from Acacia nilotica L. was studied. Leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and three... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_30381175" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The comparative in vitro antimicrobial activity of ethanol and chloroform leaves extracts from Acacia nilotica L. was studied. Leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and three Gram-negative strains. The antimicrobial action was compared with the effect of doxycycline antibiotic. The maximum zone of inhibition of 29 mm diameter was observed in Escherichia coli with ethanol extract while a minimum 8 mm zone of inhibition was found in Bacillus subtilis. Klebsiella pneumoniae showed marked resistance towards both ethanol and chloroform extracts. Among the fungal strains tested, Aspergillus flavus exhibited maximum sensitivity action of the extracts. This analysis revealed the high antimicrobial activity in the ethanol extract of A. nilotica L. than chloroform extract. It is recommended to isolate, identify and integrate the bioactive principle in these pathogens management.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30381175" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e191c3dfb2bdaab64ae44ee32a5ce0ec" rel="nofollow" data-download="{&quot;attachment_id&quot;:50830869,&quot;asset_id&quot;:30381175,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50830869/download_file?st=MTczMjg0MTk3MSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="46648359" href="https://qau.academia.edu/AbdulSamadMumtaz">Abdul Samad Mumtaz</a><script data-card-contents-for-user="46648359" type="text/json">{"id":46648359,"first_name":"Abdul","last_name":"Samad Mumtaz","domain_name":"qau","page_name":"AbdulSamadMumtaz","display_name":"Abdul Samad Mumtaz","profile_url":"https://qau.academia.edu/AbdulSamadMumtaz?f_ri=1134083","photo":"https://0.academia-photos.com/46648359/144918999/134447020/s65_abdul.samad_mumtaz.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-30381175">+2</span><div class="hidden js-additional-users-30381175"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/GulZaib6">Gul Zaib</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/YasirIhtesham">Yasir Ihtesham</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-30381175'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-30381175').html(); 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Leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and three Gram-negative strains. The antimicrobial action was compared with the effect of doxycycline antibiotic. The maximum zone of inhibition of 29 mm diameter was observed in Escherichia coli with ethanol extract while a minimum 8 mm zone of inhibition was found in Bacillus subtilis. Klebsiella pneumoniae showed marked resistance towards both ethanol and chloroform extracts. Among the fungal strains tested, Aspergillus flavus exhibited maximum sensitivity action of the extracts. This analysis revealed the high antimicrobial activity in the ethanol extract of A. nilotica L. than chloroform extract. It is recommended to isolate, identify and integrate the bioactive principle in these pathogens management.","downloadable_attachments":[{"id":50830869,"asset_id":30381175,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46648359,"first_name":"Abdul","last_name":"Samad Mumtaz","domain_name":"qau","page_name":"AbdulSamadMumtaz","display_name":"Abdul Samad Mumtaz","profile_url":"https://qau.academia.edu/AbdulSamadMumtaz?f_ri=1134083","photo":"https://0.academia-photos.com/46648359/144918999/134447020/s65_abdul.samad_mumtaz.jpg"},{"id":62527369,"first_name":"Gul","last_name":"Zaib","domain_name":"independent","page_name":"GulZaib6","display_name":"Gul Zaib","profile_url":"https://independent.academia.edu/GulZaib6?f_ri=1134083","photo":"/images/s65_no_pic.png"},{"id":57963174,"first_name":"Yasir","last_name":"Ihtesham","domain_name":"independent","page_name":"YasirIhtesham","display_name":"Yasir Ihtesham","profile_url":"https://independent.academia.edu/YasirIhtesham?f_ri=1134083","photo":"https://0.academia-photos.com/57963174/15188916/15874502/s65_yasir.ihtesham.jpg"}],"research_interests":[{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083","nofollow":false},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_26365780" data-work_id="26365780" itemscope="itemscope" 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$(".js-view-count-work_26365780").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_26365780").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="26365780"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">4</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="4083" href="https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine">Complementary and Alternative Medicine</a>,&nbsp;<script data-card-contents-for-ri="4083" type="text/json">{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a>,&nbsp;<script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="15019" href="https://www.academia.edu/Documents/in/Medicinal_Plants">Medicinal Plants</a>,&nbsp;<script data-card-contents-for-ri="15019" type="text/json">{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1134083" href="https://www.academia.edu/Documents/in/Medicinal_Plant">Medicinal Plant</a><script data-card-contents-for-ri="1134083" type="text/json">{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=26365780]'), work: {"id":26365780,"title":"Antidiabetic and genotoxic effects on Wistar rats treated with aqueous extract from Chrysobalanus icaco L","created_at":"2016-06-21T04:48:45.202-07:00","url":"https://www.academia.edu/26365780/Antidiabetic_and_genotoxic_effects_on_Wistar_rats_treated_with_aqueous_extract_from_Chrysobalanus_icaco_L?f_ri=1134083","dom_id":"work_26365780","summary":null,"downloadable_attachments":[{"id":46672182,"asset_id":26365780,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50233802,"first_name":"Rachel","last_name":"Gagliardi","domain_name":"uerj","page_name":"RachelGagliardi","display_name":"Rachel Gagliardi","profile_url":"https://uerj.academia.edu/RachelGagliardi?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":15019,"name":"Medicinal Plants","url":"https://www.academia.edu/Documents/in/Medicinal_Plants?f_ri=1134083","nofollow":false},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_67573829" data-work_id="67573829" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/67573829/Effects_of_pomegranate_seed_extract_on_liver_paraoxonase_and_bcl_xL_activities_in_rats_treated_with_cisplatin">Effects of pomegranate seed extract on liver paraoxonase and bcl-xL activities in rats treated with cisplatin</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/67573829" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="353eaca581fa255846b048425639a493" rel="nofollow" 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href="https://independent.academia.edu/ismailcan9">ismail can</a><script data-card-contents-for-user="124640705" type="text/json">{"id":124640705,"first_name":"ismail","last_name":"can","domain_name":"independent","page_name":"ismailcan9","display_name":"ismail can","profile_url":"https://independent.academia.edu/ismailcan9?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_67573829 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="67573829"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 67573829, container: ".js-paper-rank-work_67573829", }); });</script></li><li class="js-percentile-work_67573829 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: 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$(".js-view-count-work_67573829").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_67573829").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="67573829"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">6</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="4083" href="https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine">Complementary and Alternative Medicine</a>,&nbsp;<script data-card-contents-for-ri="4083" type="text/json">{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a>,&nbsp;<script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a>,&nbsp;<script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="15019" href="https://www.academia.edu/Documents/in/Medicinal_Plants">Medicinal Plants</a><script data-card-contents-for-ri="15019" type="text/json">{"id":15019,"name":"Medicinal 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})();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_64986964" data-work_id="64986964" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/64986964/Traditional_uses_of_medicinal_plants_in_Darra_Adam_Khel_NWFP_Pakistan">Traditional uses of medicinal plants in Darra Adam Khel NWFP Pakistan</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/64986964" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" 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Moon (barangi): a rare and threatened medicinal plant</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12330869" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1a25ec283e2bcb3c43c7b18f8f583431" rel="nofollow" data-download="{&quot;attachment_id&quot;:46239083,&quot;asset_id&quot;:12330869,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46239083/download_file?st=MTczMjg0MTk3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="103795960" href="https://independent.academia.edu/AshokNbri">Ashok Nbri</a><script data-card-contents-for-user="103795960" type="text/json">{"id":103795960,"first_name":"Ashok","last_name":"Nbri","domain_name":"independent","page_name":"AshokNbri","display_name":"Ashok Nbri","profile_url":"https://independent.academia.edu/AshokNbri?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text">&nbsp;and&nbsp;<span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-12330869">+1</span><div class="hidden js-additional-users-12330869"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://nbri.academia.edu/DebasisChakrabarty">Debasis Chakrabarty</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-12330869'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-12330869').html(); 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Rich. and Ludwigia decurrens Walter</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Ludwigia abyssinica and Ludwigia decurrens are two plant species of the genus Ludwigiaused traditionally for the treatment of various skin, gastrointestinal, wound and bone joint disorders in Nigeria. The antibacterial and antifungal... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_64923717" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Ludwigia abyssinica and Ludwigia decurrens are two plant species of the genus Ludwigiaused traditionally for the treatment of various skin, gastrointestinal, wound and bone joint disorders in Nigeria. The antibacterial and antifungal properties of extracts from the leaves of both plants against clinically important species of bacteria and fungi were examined. The two plant species produced activities with absolute similarity. The n-butanol extract was the most potent with maximum zone of inhibition (32.0 mm) followed by the ethyl acetate extract (12.0 to 31.0 mm) amongst other extracts (aqueous, dichloromethane and n-hexane). The n-butanol extract exhibited broad spectrum activity against all test bacteria and fungi and compared favourably with standard reference drugs – ampicillin, streptomycin and amphotericin B. The minimum inhibitory concentrations (MIC) exhibited by both n-butanol and ethyl acetate extracts against test bacteria species ranged between 0.625 to 5.0 mg ml-1 and 1...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/64923717" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6b6ae457cb9e2bc9102bc5a6022d2c68" rel="nofollow" data-download="{&quot;attachment_id&quot;:76733819,&quot;asset_id&quot;:64923717,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/76733819/download_file?st=MTczMjg0MTk3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5289449" href="https://oaife.academia.edu/FestusTaiwo">Festus Taiwo</a><script data-card-contents-for-user="5289449" type="text/json">{"id":5289449,"first_name":"Festus","last_name":"Taiwo","domain_name":"oaife","page_name":"FestusTaiwo","display_name":"Festus Taiwo","profile_url":"https://oaife.academia.edu/FestusTaiwo?f_ri=1134083","photo":"https://0.academia-photos.com/5289449/2325859/2713055/s65_festus.taiwo.jpg"}</script></span></span></li><li class="js-paper-rank-work_64923717 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="64923717"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 64923717, container: ".js-paper-rank-work_64923717", }); 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data-has-card-for-ri="255" href="https://www.academia.edu/Documents/in/Evolutionary_Psychology">Evolutionary Psychology</a>,&nbsp;<script data-card-contents-for-ri="255" type="text/json">{"id":255,"name":"Evolutionary Psychology","url":"https://www.academia.edu/Documents/in/Evolutionary_Psychology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="398" href="https://www.academia.edu/Documents/in/Paleoanthropology">Paleoanthropology</a>,&nbsp;<script data-card-contents-for-ri="398" type="text/json">{"id":398,"name":"Paleoanthropology","url":"https://www.academia.edu/Documents/in/Paleoanthropology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="767" href="https://www.academia.edu/Documents/in/Anthropology">Anthropology</a><script data-card-contents-for-ri="767" 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Disorders","url":"https://www.academia.edu/Documents/in/Substance-Related_Disorders?f_ri=1134083"},{"id":1560838,"name":"Biological Adaptation","url":"https://www.academia.edu/Documents/in/Biological_Adaptation?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_34171629" data-work_id="34171629" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/34171629/Antioxidant_anti_inflammatory_and_anticancer_activities_of_methanolic_extracts_from_Ledum_groenlandicum_Retzius">Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Ledum groenlandicum Retzius</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Labrador tea (Ledum groenlandicum Retzius) is an ericaceae widely distributed in North America. The leaves and twigs were used in Native American traditional medicine to treat several inflammatory pathologies such as asthma, rheumatisms... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_34171629" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Labrador tea (Ledum groenlandicum Retzius) is an ericaceae widely distributed in North America. The leaves and twigs were used in Native American traditional medicine to treat several inflammatory pathologies such as asthma, rheumatisms and burns. Reactive oxygen species as well as reactive nitrogen species such as nitric oxide (NO) contribute significantly to these pathologies. In this study, the antioxidant, anti-inflammatory</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/34171629" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="38b1cc8890eb5a433a7b59b03bacb4c3" rel="nofollow" data-download="{&quot;attachment_id&quot;:54092354,&quot;asset_id&quot;:34171629,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/54092354/download_file?st=MTczMjg0MTk3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44553400" href="https://independent.academia.edu/CatherineLaprise">Catherine Laprise</a><script data-card-contents-for-user="44553400" type="text/json">{"id":44553400,"first_name":"Catherine","last_name":"Laprise","domain_name":"independent","page_name":"CatherineLaprise","display_name":"Catherine Laprise","profile_url":"https://independent.academia.edu/CatherineLaprise?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_34171629 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="34171629"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 34171629, container: ".js-paper-rank-work_34171629", }); 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$(".js-view-count[data-work-id=34171629]").text(description); $(".js-view-count-work_34171629").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_34171629").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="34171629"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">32</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4083" href="https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine">Complementary and Alternative Medicine</a>,&nbsp;<script data-card-contents-for-ri="4083" type="text/json">{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4086" href="https://www.academia.edu/Documents/in/Traditional_Medicine">Traditional Medicine</a>,&nbsp;<script data-card-contents-for-ri="4086" type="text/json">{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a>,&nbsp;<script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12981" href="https://www.academia.edu/Documents/in/Enzyme_Inhibitors">Enzyme Inhibitors</a><script data-card-contents-for-ri="12981" type="text/json">{"id":12981,"name":"Enzyme Inhibitors","url":"https://www.academia.edu/Documents/in/Enzyme_Inhibitors?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=34171629]'), work: {"id":34171629,"title":"Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Ledum groenlandicum Retzius","created_at":"2017-08-08T16:14:23.979-07:00","url":"https://www.academia.edu/34171629/Antioxidant_anti_inflammatory_and_anticancer_activities_of_methanolic_extracts_from_Ledum_groenlandicum_Retzius?f_ri=1134083","dom_id":"work_34171629","summary":"Labrador tea (Ledum groenlandicum Retzius) is an ericaceae widely distributed in North America. The leaves and twigs were used in Native American traditional medicine to treat several inflammatory pathologies such as asthma, rheumatisms and burns. Reactive oxygen species as well as reactive nitrogen species such as nitric oxide (NO) contribute significantly to these pathologies. 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Inhibitors","url":"https://www.academia.edu/Documents/in/Enzyme_Inhibitors?f_ri=1134083","nofollow":false},{"id":14032,"name":"Ethnopharmacology","url":"https://www.academia.edu/Documents/in/Ethnopharmacology?f_ri=1134083"},{"id":14080,"name":"Pharmacognosy","url":"https://www.academia.edu/Documents/in/Pharmacognosy?f_ri=1134083"},{"id":15504,"name":"Native American","url":"https://www.academia.edu/Documents/in/Native_American?f_ri=1134083"},{"id":17491,"name":"Macrophages","url":"https://www.academia.edu/Documents/in/Macrophages?f_ri=1134083"},{"id":51711,"name":"Antioxidants","url":"https://www.academia.edu/Documents/in/Antioxidants?f_ri=1134083"},{"id":54114,"name":"Canada","url":"https://www.academia.edu/Documents/in/Canada?f_ri=1134083"},{"id":82978,"name":"Reactive Oxygen Species","url":"https://www.academia.edu/Documents/in/Reactive_Oxygen_Species?f_ri=1134083"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=1134083"},{"id":93922,"name":"Nitric 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Activity","url":"https://www.academia.edu/Documents/in/Anti_Inflammatory_Activity?f_ri=1134083"},{"id":789968,"name":"Extract","url":"https://www.academia.edu/Documents/in/Extract?f_ri=1134083"},{"id":936268,"name":"Colon Carcinoma","url":"https://www.academia.edu/Documents/in/Colon_Carcinoma?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1157148,"name":"Cell Survival","url":"https://www.academia.edu/Documents/in/Cell_Survival?f_ri=1134083"},{"id":1256747,"name":"Oxidation-Reduction","url":"https://www.academia.edu/Documents/in/Oxidation-Reduction?f_ri=1134083"},{"id":1358142,"name":"Methyl Ester","url":"https://www.academia.edu/Documents/in/Methyl_Ester?f_ri=1134083"},{"id":1554614,"name":"Lung Carcinoma","url":"https://www.academia.edu/Documents/in/Lung_Carcinoma?f_ri=1134083"},{"id":1745595,"name":"Solvents","url":"https://www.academia.edu/Documents/in/Solvents?f_ri=1134083"},{"id":1758650,"name":"Triterpenes","url":"https://www.academia.edu/Documents/in/Triterpenes?f_ri=1134083"},{"id":1905343,"name":"Plant Leaves","url":"https://www.academia.edu/Documents/in/Plant_Leaves?f_ri=1134083"},{"id":2281154,"name":"Terpenoid","url":"https://www.academia.edu/Documents/in/Terpenoid?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_3827273" data-work_id="3827273" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/3827273/A_phase_I_clinical_study_of_Andrographis_paniculata_fixed_combination_Kan_Jang_versus_ginseng_and_valerian_on_the_semen_quality_of_healthy_male_subjects">A phase I clinical study of Andrographis paniculata fixed combination Kan Jang™ versus ginseng and valerian on the semen quality of healthy male subjects</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The safety of different doses of Kan Jang™ – a fixed combination of Andrographis paniculata special extract (SHA-10) and Acanthopanax senticosus – compared to two extensively used medicinal plants, Valeriana officinalis and Panax ginseng... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_3827273" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The safety of different doses of Kan Jang™ – a fixed combination of Andrographis paniculata special extract (SHA-10) and Acanthopanax senticosus – compared to two extensively used medicinal plants, Valeriana officinalis and Panax ginseng in the form of standardized extracts, has been examined. A phase I clinical study was designed to evaluate the effect on semen quality of healthy males in terms of spermatogenesis and quality of semen. The results of the study revealed no significant negative effect of Kan Jang on male semen quality and fertility, but rather a positive trend with respect to the number of spermatozoids in the whole ejaculate, the percentage of active (normokinetic) forms of spermatozoids, and fertility indexes, together with a decrease in the percentage of inactive (diskinetic) forms of spermatozoids. In the group receiving ginseng, no significant negative effects on the fertility parameters were revealed and there was a clear decrease in the percentage of diskinetic forms of spermatozoids. Subjects receiving valerian showed a temporary increase in the percentage of normokinetic spermatozoids and a decrease in diskinetic forms, but these changes had no effect on fertility indices. The results indicate that Kan Jang, ginseng and valerian are safe with respect to effects on human male sterility when administered at dose levels corresponding to approximately 3 times the human daily dose.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3827273" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4f20beb82805a37ff4aa6e01071757ac" rel="nofollow" data-download="{&quot;attachment_id&quot;:50123171,&quot;asset_id&quot;:3827273,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50123171/download_file?st=MTczMjg0MTk3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="4709668" href="https://independent.academia.edu/AlexanderPanosyan">Alexander Panossian</a><script data-card-contents-for-user="4709668" type="text/json">{"id":4709668,"first_name":"Alexander","last_name":"Panossian","domain_name":"independent","page_name":"AlexanderPanosyan","display_name":"Alexander Panossian","profile_url":"https://independent.academia.edu/AlexanderPanosyan?f_ri=1134083","photo":"https://0.academia-photos.com/4709668/1988055/34961888/s65_alexander.panossian.jpeg"}</script></span></span></li><li class="js-paper-rank-work_3827273 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="3827273"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 3827273, container: ".js-paper-rank-work_3827273", }); 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A phase I clinical study was designed to evaluate the effect on semen quality of healthy males in terms of spermatogenesis and quality of semen. The results of the study revealed no significant negative effect of Kan Jang on male semen quality and fertility, but rather a positive trend with respect to the number of spermatozoids in the whole ejaculate, the percentage of active (normokinetic) forms of spermatozoids, and fertility indexes, together with a decrease in the percentage of inactive (diskinetic) forms of spermatozoids. In the group receiving ginseng, no significant negative effects on the fertility parameters were revealed and there was a clear decrease in the percentage of diskinetic forms of spermatozoids. Subjects receiving valerian showed a temporary increase in the percentage of normokinetic spermatozoids and a decrease in diskinetic forms, but these changes had no effect on fertility indices. The results indicate that Kan Jang, ginseng and valerian are safe with respect to effects on human male sterility when administered at dose levels corresponding to approximately 3 times the human daily dose.","downloadable_attachments":[{"id":50123171,"asset_id":3827273,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":4709668,"first_name":"Alexander","last_name":"Panossian","domain_name":"independent","page_name":"AlexanderPanosyan","display_name":"Alexander Panossian","profile_url":"https://independent.academia.edu/AlexanderPanosyan?f_ri=1134083","photo":"https://0.academia-photos.com/4709668/1988055/34961888/s65_alexander.panossian.jpeg"}],"research_interests":[{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":8954,"name":"Fertility","url":"https://www.academia.edu/Documents/in/Fertility?f_ri=1134083","nofollow":false},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=1134083"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1134083"},{"id":44842,"name":"Phytomedicine","url":"https://www.academia.edu/Documents/in/Phytomedicine?f_ri=1134083"},{"id":52027,"name":"Phytotherapy","url":"https://www.academia.edu/Documents/in/Phytotherapy?f_ri=1134083"},{"id":75577,"name":"Spermatogenesis","url":"https://www.academia.edu/Documents/in/Spermatogenesis?f_ri=1134083"},{"id":165105,"name":"Male Fertility","url":"https://www.academia.edu/Documents/in/Male_Fertility?f_ri=1134083"},{"id":269496,"name":"Panax","url":"https://www.academia.edu/Documents/in/Panax?f_ri=1134083"},{"id":354056,"name":"Plant extracts","url":"https://www.academia.edu/Documents/in/Plant_extracts?f_ri=1134083"},{"id":546356,"name":"Clinical Study","url":"https://www.academia.edu/Documents/in/Clinical_Study?f_ri=1134083"},{"id":573466,"name":"Male Sterility","url":"https://www.academia.edu/Documents/in/Male_Sterility?f_ri=1134083"},{"id":749302,"name":"Indexation","url":"https://www.academia.edu/Documents/in/Indexation?f_ri=1134083"},{"id":862371,"name":"Spermatozoa","url":"https://www.academia.edu/Documents/in/Spermatozoa?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1221081,"name":"Semen Quality","url":"https://www.academia.edu/Documents/in/Semen_Quality?f_ri=1134083"},{"id":2146368,"name":"Andrographis","url":"https://www.academia.edu/Documents/in/Andrographis?f_ri=1134083"},{"id":2526384,"name":"Valerian","url":"https://www.academia.edu/Documents/in/Valerian?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_4169572 coauthored" data-work_id="4169572" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/4169572/The_potential_antileishmanial_activity_of_some_Sudanese_medicinal_plants">The potential antileishmanial activity of some Sudanese medicinal plants</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div 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href="https://unip.academia.edu/ClaudiaMoraes">Claudia Moraes</a><script data-card-contents-for-user="15338859" type="text/json">{"id":15338859,"first_name":"Claudia","last_name":"Moraes","domain_name":"unip","page_name":"ClaudiaMoraes","display_name":"Claudia Moraes","profile_url":"https://unip.academia.edu/ClaudiaMoraes?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8010051 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8010051"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8010051, container: ".js-paper-rank-work_8010051", }); });</script></li><li class="js-percentile-work_8010051 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 8010051; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_8010051"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_8010051 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="8010051"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 8010051; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=8010051]").text(description); $(".js-view-count-work_8010051").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8010051").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8010051"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">17</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2898" href="https://www.academia.edu/Documents/in/Pain">Pain</a>,&nbsp;<script data-card-contents-for-ri="2898" type="text/json">{"id":2898,"name":"Pain","url":"https://www.academia.edu/Documents/in/Pain?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4083" href="https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine">Complementary and Alternative Medicine</a>,&nbsp;<script data-card-contents-for-ri="4083" type="text/json">{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4086" href="https://www.academia.edu/Documents/in/Traditional_Medicine">Traditional Medicine</a>,&nbsp;<script data-card-contents-for-ri="4086" type="text/json">{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a><script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8010051]'), work: {"id":8010051,"title":"Antinociceptive activity of Amazonian Copaiba oils","created_at":"2014-08-18T03:48:31.402-07:00","url":"https://www.academia.edu/8010051/Antinociceptive_activity_of_Amazonian_Copaiba_oils?f_ri=1134083","dom_id":"work_8010051","summary":null,"downloadable_attachments":[{"id":48254672,"asset_id":8010051,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":15338859,"first_name":"Claudia","last_name":"Moraes","domain_name":"unip","page_name":"ClaudiaMoraes","display_name":"Claudia Moraes","profile_url":"https://unip.academia.edu/ClaudiaMoraes?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":2898,"name":"Pain","url":"https://www.academia.edu/Documents/in/Pain?f_ri=1134083","nofollow":false},{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":4086,"name":"Traditional Medicine","url":"https://www.academia.edu/Documents/in/Traditional_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":9821,"name":"Brazil","url":"https://www.academia.edu/Documents/in/Brazil?f_ri=1134083"},{"id":14032,"name":"Ethnopharmacology","url":"https://www.academia.edu/Documents/in/Ethnopharmacology?f_ri=1134083"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=1134083"},{"id":316233,"name":"Crude Oil","url":"https://www.academia.edu/Documents/in/Crude_Oil?f_ri=1134083"},{"id":396733,"name":"Fabaceae","url":"https://www.academia.edu/Documents/in/Fabaceae?f_ri=1134083"},{"id":723149,"name":"Acetic Acid","url":"https://www.academia.edu/Documents/in/Acetic_Acid?f_ri=1134083"},{"id":802213,"name":"Lethal Dose","url":"https://www.academia.edu/Documents/in/Lethal_Dose?f_ri=1134083"},{"id":956370,"name":"Opioid Receptor","url":"https://www.academia.edu/Documents/in/Opioid_Receptor?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1225893,"name":"Effective Dose","url":"https://www.academia.edu/Documents/in/Effective_Dose?f_ri=1134083"},{"id":1262481,"name":"Pain Measurement","url":"https://www.academia.edu/Documents/in/Pain_Measurement?f_ri=1134083"},{"id":1436039,"name":"Plant Oils","url":"https://www.academia.edu/Documents/in/Plant_Oils?f_ri=1134083"},{"id":1491514,"name":"*Hot Temperature","url":"https://www.academia.edu/Documents/in/_Hot_Temperature?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_9031222" data-work_id="9031222" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/9031222/Principles_of_classification_of_medicinal_plants_as_hyperaccumulators_or_excluders">Principles of classification of medicinal plants as hyperaccumulators or excluders</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Strategies of plants, known as metallophytes, in response to metal excess are explored. Specific features of medicinal plants related to metal exposition are discussed. Different parameters used for metallophyte classification are... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_9031222" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Strategies of plants, known as metallophytes, in response to metal excess are explored. Specific features of medicinal plants related to metal exposition are discussed. Different parameters used for metallophyte classification are discussed. Bioaccumulation and translocation factors are characterized. Chamomile (Matricaria recutita L.), one of the most important medicinal plants, is presented as a case history. Based on actual knowledge of plant response to metal excess and published data related to chamomile, it has been concluded that this plant species is Cd hyper/accumulator. Thus, chamomile can manifest high potential for cleaning-up (phytoremediation) of the soils contaminated with cadmium. However, it should be stressed that cultivation of this medicinal plant under natural conditions for pharmaceutical use should be carefully supervised.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/9031222" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fa1b5ee5ea45928517919342ac31f894" rel="nofollow" data-download="{&quot;attachment_id&quot;:47908283,&quot;asset_id&quot;:9031222,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47908283/download_file?st=MTczMjg0MTk3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="20352430" href="https://independent.academia.edu/PavlovicKatarina">Katarina Pavlovic</a><script data-card-contents-for-user="20352430" type="text/json">{"id":20352430,"first_name":"Katarina","last_name":"Pavlovic","domain_name":"independent","page_name":"PavlovicKatarina","display_name":"Katarina Pavlovic","profile_url":"https://independent.academia.edu/PavlovicKatarina?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_9031222 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="9031222"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 9031222, container: ".js-paper-rank-work_9031222", }); });</script></li><li class="js-percentile-work_9031222 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 9031222; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_9031222"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_9031222 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="9031222"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 9031222; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=9031222]").text(description); $(".js-view-count-work_9031222").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_9031222").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="9031222"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">5</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a>,&nbsp;<script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="67433" href="https://www.academia.edu/Documents/in/Soil_contamination">Soil contamination</a>,&nbsp;<script data-card-contents-for-ri="67433" type="text/json">{"id":67433,"name":"Soil contamination","url":"https://www.academia.edu/Documents/in/Soil_contamination?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="586072" href="https://www.academia.edu/Documents/in/Plant_species">Plant species</a>,&nbsp;<script data-card-contents-for-ri="586072" type="text/json">{"id":586072,"name":"Plant species","url":"https://www.academia.edu/Documents/in/Plant_species?f_ri=1134083","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1005027" href="https://www.academia.edu/Documents/in/Case_History">Case History</a><script data-card-contents-for-ri="1005027" type="text/json">{"id":1005027,"name":"Case History","url":"https://www.academia.edu/Documents/in/Case_History?f_ri=1134083","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=9031222]'), work: {"id":9031222,"title":"Principles of classification of medicinal plants as hyperaccumulators or excluders","created_at":"2014-10-30T04:35:17.969-07:00","url":"https://www.academia.edu/9031222/Principles_of_classification_of_medicinal_plants_as_hyperaccumulators_or_excluders?f_ri=1134083","dom_id":"work_9031222","summary":"Strategies of plants, known as metallophytes, in response to metal excess are explored. Specific features of medicinal plants related to metal exposition are discussed. Different parameters used for metallophyte classification are discussed. Bioaccumulation and translocation factors are characterized. Chamomile (Matricaria recutita L.), one of the most important medicinal plants, is presented as a case history. Based on actual knowledge of plant response to metal excess and published data related to chamomile, it has been concluded that this plant species is Cd hyper/accumulator. Thus, chamomile can manifest high potential for cleaning-up (phytoremediation) of the soils contaminated with cadmium. However, it should be stressed that cultivation of this medicinal plant under natural conditions for pharmaceutical use should be carefully supervised.","downloadable_attachments":[{"id":47908283,"asset_id":9031222,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":20352430,"first_name":"Katarina","last_name":"Pavlovic","domain_name":"independent","page_name":"PavlovicKatarina","display_name":"Katarina Pavlovic","profile_url":"https://independent.academia.edu/PavlovicKatarina?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":67433,"name":"Soil contamination","url":"https://www.academia.edu/Documents/in/Soil_contamination?f_ri=1134083","nofollow":false},{"id":586072,"name":"Plant species","url":"https://www.academia.edu/Documents/in/Plant_species?f_ri=1134083","nofollow":false},{"id":1005027,"name":"Case History","url":"https://www.academia.edu/Documents/in/Case_History?f_ri=1134083","nofollow":false},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_10894077" data-work_id="10894077" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/10894077/Anticonvulsant_activities_of_ethanolic_extract_and_aqueous_fraction_isolated_from_Delphinium_denudatum">Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Dried roots of Delphinium denudatum Wall. are a popular folk remedy for the treatment of epilepsy in the traditional Unani system of medicine in the sub-continent. We carried out anticonvulsant screening of the ethanolic extract (EE) and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_10894077" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Dried roots of Delphinium denudatum Wall. are a popular folk remedy for the treatment of epilepsy in the traditional Unani system of medicine in the sub-continent. We carried out anticonvulsant screening of the ethanolic extract (EE) and aqueous fraction (AF) of this plant utilising the maximal electroshock (MEST) and subcutaneous pentylenetetrazole (scPTZ), bicuculline (scBIC), picrotoxin (scPTX) and strychnine (scSTN) tests for anticonvulsant activity. EE had weak dose-dependent anticonvulsant effects on seizures induced by PTZ and BIC. AF exhibited dose-dependent activity against hind limb tonic extension phase (HLTE) of MEST and comparatively stronger anticonvulsant activity against seizures induced by PTZ and BIC. The results suggest the presence of potent anticonvulsant compounds in AF of D. denudatum and deserve further investigation for isolation of active compounds and elucidation of the mechanism of anticonvulsant action.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/10894077" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0da47fe236213a5253422f5f7ec03369" rel="nofollow" data-download="{&quot;attachment_id&quot;:47044737,&quot;asset_id&quot;:10894077,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47044737/download_file?st=MTczMjg0MTk3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26442069" href="https://independent.academia.edu/MohsinRaza48">Mohsin Raza</a><script data-card-contents-for-user="26442069" type="text/json">{"id":26442069,"first_name":"Mohsin","last_name":"Raza","domain_name":"independent","page_name":"MohsinRaza48","display_name":"Mohsin Raza","profile_url":"https://independent.academia.edu/MohsinRaza48?f_ri=1134083","photo":"https://0.academia-photos.com/26442069/9613027/10707780/s65_mohsin.raza.jpg_oh_29d3fff67095a46885ab2a2e0fc4508e_oe_55e73432___gda___1442196303_dd497cf0c68d5cae1393ac27c678c235"}</script></span></span></li><li class="js-paper-rank-work_10894077 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="10894077"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 10894077, container: ".js-paper-rank-work_10894077", }); 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We carried out anticonvulsant screening of the ethanolic extract (EE) and aqueous fraction (AF) of this plant utilising the maximal electroshock (MEST) and subcutaneous pentylenetetrazole (scPTZ), bicuculline (scBIC), picrotoxin (scPTX) and strychnine (scSTN) tests for anticonvulsant activity. EE had weak dose-dependent anticonvulsant effects on seizures induced by PTZ and BIC. AF exhibited dose-dependent activity against hind limb tonic extension phase (HLTE) of MEST and comparatively stronger anticonvulsant activity against seizures induced by PTZ and BIC. The results suggest the presence of potent anticonvulsant compounds in AF of D. denudatum and deserve further investigation for isolation of active compounds and elucidation of the mechanism of anticonvulsant action.","downloadable_attachments":[{"id":47044737,"asset_id":10894077,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26442069,"first_name":"Mohsin","last_name":"Raza","domain_name":"independent","page_name":"MohsinRaza48","display_name":"Mohsin Raza","profile_url":"https://independent.academia.edu/MohsinRaza48?f_ri=1134083","photo":"https://0.academia-photos.com/26442069/9613027/10707780/s65_mohsin.raza.jpg_oh_29d3fff67095a46885ab2a2e0fc4508e_oe_55e73432___gda___1442196303_dd497cf0c68d5cae1393ac27c678c235"}],"research_interests":[{"id":623,"name":"Neurology","url":"https://www.academia.edu/Documents/in/Neurology?f_ri=1134083","nofollow":false},{"id":2215,"name":"Water","url":"https://www.academia.edu/Documents/in/Water?f_ri=1134083","nofollow":false},{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":14032,"name":"Ethnopharmacology","url":"https://www.academia.edu/Documents/in/Ethnopharmacology?f_ri=1134083"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=1134083"},{"id":119292,"name":"Ranunculaceae","url":"https://www.academia.edu/Documents/in/Ranunculaceae?f_ri=1134083"},{"id":121705,"name":"Ethanol","url":"https://www.academia.edu/Documents/in/Ethanol?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1422473,"name":"Bicuculline","url":"https://www.academia.edu/Documents/in/Bicuculline?f_ri=1134083"},{"id":1745595,"name":"Solvents","url":"https://www.academia.edu/Documents/in/Solvents?f_ri=1134083"},{"id":1957847,"name":"Pentylenetetrazole","url":"https://www.academia.edu/Documents/in/Pentylenetetrazole?f_ri=1134083"},{"id":2158441,"name":"Strychnine","url":"https://www.academia.edu/Documents/in/Strychnine?f_ri=1134083"},{"id":2329101,"name":"Electroshock","url":"https://www.academia.edu/Documents/in/Electroshock?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12822460" data-work_id="12822460" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12822460/Clinical_Effects_Produced_by_a_Standardized_Herbal_Medicinal_Product_of_Hibiscus_sabdariffa_on_Patients_with_Hypertension_A_Randomized_Double_blind_Lisinopril_Controlled_Clinical_Trial">Clinical Effects Produced by a Standardized Herbal Medicinal Product of Hibiscus sabdariffa on Patients with Hypertension. A Randomized, Double-blind, Lisinopril-Controlled Clinical Trial</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12822460" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a7fda29976e912916ea2b242953c0df0" rel="nofollow" data-download="{&quot;attachment_id&quot;:45911722,&quot;asset_id&quot;:12822460,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45911722/download_file?st=MTczMjg0MTk3Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31912745" href="https://cis.academia.edu/AlejandroZamilpa">Alejandro Zamilpa</a><script data-card-contents-for-user="31912745" type="text/json">{"id":31912745,"first_name":"Alejandro","last_name":"Zamilpa","domain_name":"cis","page_name":"AlejandroZamilpa","display_name":"Alejandro Zamilpa","profile_url":"https://cis.academia.edu/AlejandroZamilpa?f_ri=1134083","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12822460 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12822460"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12822460, container: ".js-paper-rank-work_12822460", }); 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A Randomized, Double-blind, Lisinopril-Controlled Clinical Trial","created_at":"2015-06-05T14:32:48.531-07:00","url":"https://www.academia.edu/12822460/Clinical_Effects_Produced_by_a_Standardized_Herbal_Medicinal_Product_of_Hibiscus_sabdariffa_on_Patients_with_Hypertension_A_Randomized_Double_blind_Lisinopril_Controlled_Clinical_Trial?f_ri=1134083","dom_id":"work_12822460","summary":null,"downloadable_attachments":[{"id":45911722,"asset_id":12822460,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31912745,"first_name":"Alejandro","last_name":"Zamilpa","domain_name":"cis","page_name":"AlejandroZamilpa","display_name":"Alejandro Zamilpa","profile_url":"https://cis.academia.edu/AlejandroZamilpa?f_ri=1134083","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=1134083","nofollow":false},{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=1134083","nofollow":false},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=1134083","nofollow":false},{"id":44297,"name":"Herbal Medicine","url":"https://www.academia.edu/Documents/in/Herbal_Medicine?f_ri=1134083","nofollow":false},{"id":52027,"name":"Phytotherapy","url":"https://www.academia.edu/Documents/in/Phytotherapy?f_ri=1134083"},{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=1134083"},{"id":88321,"name":"Blood Pressure","url":"https://www.academia.edu/Documents/in/Blood_Pressure?f_ri=1134083"},{"id":201433,"name":"Hibiscus","url":"https://www.academia.edu/Documents/in/Hibiscus?f_ri=1134083"},{"id":354056,"name":"Plant extracts","url":"https://www.academia.edu/Documents/in/Plant_extracts?f_ri=1134083"},{"id":373249,"name":"Electrolytes","url":"https://www.academia.edu/Documents/in/Electrolytes?f_ri=1134083"},{"id":584597,"name":"Controlled Clinical Trial","url":"https://www.academia.edu/Documents/in/Controlled_Clinical_Trial?f_ri=1134083"},{"id":1134083,"name":"Medicinal Plant","url":"https://www.academia.edu/Documents/in/Medicinal_Plant?f_ri=1134083"},{"id":1227768,"name":"Angiotensin Converting Enzyme Inhibitors","url":"https://www.academia.edu/Documents/in/Angiotensin_Converting_Enzyme_Inhibitors?f_ri=1134083"},{"id":1322750,"name":"Planta","url":"https://www.academia.edu/Documents/in/Planta?f_ri=1134083"},{"id":1776588,"name":"Lisinopril","url":"https://www.academia.edu/Documents/in/Lisinopril?f_ri=1134083"}]}, }) } })();</script></ul></li></ul></div></div></div><div class="u-taCenter Pagination"><ul class="pagination"><li class="next_page"><a 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