CINXE.COM

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class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><ul class="clp-secondary-menu"><li><a data-colorbox-inline=".cta-header-secondary-menu-Transparantie">Transparantie</a></li> <li><a data-colorbox-inline=".cta-header-secondary-menu-Investeerders">Investeerders</a></li> <li><a data-colorbox-inline=".cta-header-secondary-menu-CARRIÈRES">CARRIÈRES</a></li> </ul><div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-Transparantie popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">U WORDT NU DOORGESCHAKELD</h2> <p class="text-align-center">U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</p> <p class="text-align-center"><a class="button-more text-center" href="/transparency-dutch">DOORGAAN</a></p> </div> </div> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div 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class="clp-mobile-header-middle container-fluid"> <div class="mobile-header-language"> <div class="language-block"> <div class="region region-clp-mobile-language-block"> <section id="block-language-5" class="block block-block-content block-block-content5a7dc698-6efe-4c02-a3cd-adb2377d4faf clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><div class="language block" id="language-switcher-icon">language<i class="fas fa-angle-down"></i></div> </div> </section> </div> </div> <div class="language-block-switcher"> <div class="region region-clp-mobile-language-switcher"> <section id="block-languageswitcherforclpnetherlands" class="block block-block-content block-block-contentb8d1ad2e-5c8d-46e1-a5b3-231fbce9c02c clearfix"> <div class="field field--name-field-language-link field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--987 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Global</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--988 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Oostenrijk</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-austria">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--989 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">België </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-belgium-dutch">Nederlands</a></div> <div class="field--item"><a href="/alnylam-belgium-french">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--990 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Brazilië</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.com.br/">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--991 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Canada</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.ca/fr">Français</a></div> <div class="field--item"><a href="https://www.alnylam.ca/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--992 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Tsjechië </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-czech-republic">Čeština</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--993 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Denemarken</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-denmark">Dansk</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--994 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Frankrijk</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.fr/">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--995 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Duitsland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.de/">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--996 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Ierland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-ireland">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--997 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Italië</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.it/">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--998 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Japan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.jp/">Japanese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--999 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Luxemburg</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-luxembourg-french">Français</a></div> <div class="field--item"><a href="/alnylam-luxembourg-german">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1000 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Nederland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-netherlands">Nederlands</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1001 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Portugal</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-portugal">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1002 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Spanje</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-espana">Español</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1003 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Zweden</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-sverige">Svenska</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1004 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Zwitserland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-switzerland-french">Français</a></div> <div class="field--item"><a href="/alnylam-switzerland-german">Deutsch</a></div> <div class="field--item"><a href="/alnylam-switzerland-italian">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1005 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taiwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">Traditional Chinese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1006 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Verenigd Koninkrijk</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> <div class="mobile-header-logo"> <div class="region region-clp-mobile-logo"> <section id="block-clplogo-2" class="block block-block-content block-block-contentbb568d43-f6bc-492d-b5aa-ecead699fbce clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p><img alt="Alnylam® Pharmaceuticals Logo" src="/themes/custom/alnylam/logo.svg" /></p> </div> </section> </div> </div> </div> <div class="clp-mobile-header-bottom container-fluid"> <div class="clp-mobile-header-cta"> <div class="region region-clp-mobile-cta"> <section id="block-clpheaderblockfornetherlands-2" class="block block-block-content block-block-content3c546671-ca6c-42cd-bcf4-45839ad2f455 clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p><a data-colorbox-inline=".cta-header-netherlands">Bezoek de internationale website van Alnylam (in het Engels) ›</a></p> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-netherlands popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">U WORDT NU DOORGESCHAKELD</h2> <p class="text-center text-align-center">U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</p> <p class="text-align-center"><a class="button-more text-center" href="/">DOORGAAN</a></p> </div> </div> </div> </section> </div> </div> </div> </div> <div id="clp-whole-header-top" class="container-fluid"> <div class="site-branding-menu-wrapper .row"> <div class="col-sm-4 site-branding"> <div class="clp-header-top_left"> <div class="region region-clp-header-top-left"> <section id="block-clplogo" class="block block-block-content block-block-contentbb568d43-f6bc-492d-b5aa-ecead699fbce clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p><img alt="Alnylam® Pharmaceuticals Logo" src="/themes/custom/alnylam/logo.svg" /></p> </div> </section> </div> </div> </div> <div class="col-sm-8 menu"> <div class="row secondary-menu"> <div class="clp-header-right-top"> <div class="region region-clp-header-right-top"> <section id="block-secondarymenuclpnetherlands" class="block block-block-content block-block-contentef6fbfed-675d-4f75-8463-350c3ac815b2 clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><ul class="clp-secondary-menu"><li><a data-colorbox-inline=".cta-header-secondary-menu-Transparantie">Transparantie</a></li> <li><a data-colorbox-inline=".cta-header-secondary-menu-Investeerders">Investeerders</a></li> <li><a data-colorbox-inline=".cta-header-secondary-menu-CARRIÈRES">CARRIÈRES</a></li> </ul><div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-Transparantie popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">U WORDT NU DOORGESCHAKELD</h2> <p class="text-align-center">U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</p> <p class="text-align-center"><a class="button-more text-center" href="/transparency-dutch">DOORGAAN</a></p> </div> </div> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-Investeerders popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">U WORDT NU DOORGESCHAKELD</h2> <p class="text-align-center">U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</p> <p class="text-align-center"><a class="button-more text-center" href="https://investors.alnylam.com/">DOORGAAN</a></p> </div> </div> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-CARRIÈRES popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">U WORDT NU DOORGESCHAKELD</h2> <p class="text-align-center">U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</p> <p class="text-align-center"><a class="button-more text-center" href="/careers/">DOORGAAN</a></p> </div> </div> </div> </section> <section id="block-language-4" class="block block-block-content block-block-content5a7dc698-6efe-4c02-a3cd-adb2377d4faf clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><div class="language block" id="language-switcher-icon">language<i class="fas fa-angle-down"></i></div> </div> </section> </div> </div> </div> <div class="row ext-cta"> <div class="clp-header-right-bottom"> <div class="region region-clp-header-right-bottom"> <section id="block-clpheaderblockfornetherlands" class="block block-block-content block-block-content3c546671-ca6c-42cd-bcf4-45839ad2f455 clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p><a data-colorbox-inline=".cta-header-netherlands">Bezoek de internationale website van Alnylam (in het Engels) ›</a></p> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-netherlands popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">U WORDT NU DOORGESCHAKELD</h2> <p class="text-center text-align-center">U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</p> <p class="text-align-center"><a class="button-more text-center" href="/">DOORGAAN</a></p> </div> </div> </div> </section> </div> </div> </div> <div class="clp-language-switcher-block-wrapper"> <div class="clp-language-switcher-block"> <div class="region region-clp-header-language-block"> <section id="block-languageswitcherforclpnetherlands-2" class="block block-block-content block-block-contentb8d1ad2e-5c8d-46e1-a5b3-231fbce9c02c clearfix"> <div class="field field--name-field-language-link field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--987 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Global</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--988 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Oostenrijk</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-austria">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--989 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">België </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-belgium-dutch">Nederlands</a></div> <div class="field--item"><a href="/alnylam-belgium-french">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--990 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Brazilië</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.com.br/">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--991 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Canada</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.ca/fr">Français</a></div> <div class="field--item"><a href="https://www.alnylam.ca/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--992 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Tsjechië </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-czech-republic">Čeština</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--993 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Denemarken</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-denmark">Dansk</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--994 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Frankrijk</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.fr/">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--995 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Duitsland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.de/">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--996 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Ierland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-ireland">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--997 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Italië</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.it/">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--998 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Japan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.jp/">Japanese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--999 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Luxemburg</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-luxembourg-french">Français</a></div> <div class="field--item"><a href="/alnylam-luxembourg-german">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1000 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Nederland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-netherlands">Nederlands</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1001 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Portugal</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-portugal">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1002 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Spanje</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-espana">Español</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1003 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Zweden</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-sverige">Svenska</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1004 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Zwitserland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-switzerland-french">Français</a></div> <div class="field--item"><a href="/alnylam-switzerland-german">Deutsch</a></div> <div class="field--item"><a href="/alnylam-switzerland-italian">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1005 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taiwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">Traditional Chinese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1006 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Verenigd Koninkrijk</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> </div> </div> </div> </header> <div id="maindiv" class="container-fluid"> <main id="midcontent-area" class="column main-content"> <div id="content"> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <article data-history-node-id="697" role="article" about="/alnylam-netherlands" class="clp full clearfix"> <div class="content"> <div class="field field--name-field-add-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1437 paragraph--view-mode--default"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1437 paragraph--view-mode--default"> <div id="simple-banner-with-text-wrapper" style="background: url(/sites/default/files/2022-04/CLP_header_slider_hero.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:1130px;margin:auto;"> <div class="upper-text"> <h2>Aan diegenen die zeggen: “onmogelijk, onpraktisch, onrealistisch”, zeggen we:</h2> <h1>Uitdaging Aangenomen</h1> <p>We ontwikkelen een vernieuwende categorie geneesmiddelen, RNAi-therapie genoemd, waarvan we denken dat ze het potentieel hebben om de levens van mensen met zeldzame ziekten te veranderen.</p> </div> </div> </div> <div class="mobile-upper-text"> <h2>Aan diegenen die zeggen: “onmogelijk, onpraktisch, onrealistisch”, zeggen we:</h2> <h1>Uitdaging Aangenomen</h1> <p>We ontwikkelen een vernieuwende categorie geneesmiddelen, RNAi-therapie genoemd, waarvan we denken dat ze het potentieel hebben om de levens van mensen met zeldzame ziekten te veranderen.</p> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-banner-overlay paragraph-id--1439 paragraph--view-mode--default"> <div id="clp-banner-overlay"> <div class="banner-text-wrapper" style="width:1130px; margin:auto;"> <div class="text-box"> <section> <h1 class="text-align-center"><strong>EEN PIONIER IN ONTWIKKELING</strong></h1> <p class="text-align-center">Alnylam leidt de vertaling van RNA-interferentie (RNAi) naar een vernieuwende categorie medicijnen voor patiënten met beperkte of inadequate opties voor behandeling. RNAi-therapie vertegenwoordigt een op de Nobelprijs gebaseerde wetenschap: een sterke en klinisch bewezen aanpak voor de behandeling van een breed scala aan ernstige en invaliderende ziekten.</p> <p class="text-align-center">Alnylam, opgericht in 2002, past een gedurfde visie toe door wetenschappelijke mogelijkheid om te zetten in werkelijkheid, met een robuust ontwikkelingsplatform en een lange pijplijn van geneesmiddelenonderzoek, waaronder vier kandidaat-producten die zich in een laat stadium van ontwikkeling bevinden.</p> </section> <div class="counter-box"> <h3 class="text-center"> </h3> <div class="row"> <div class="col-sm-2"> <h1 class="text-align-center"><span>2k</span></h1> <p class="count-text text-align-center">Werknemers</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>21</span></h1> <p class="count-text text-align-center">Landen</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>11</span></h1> <p class="count-text text-align-center">Programma's in klinische ontwikkeling</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>5</span></h1> <p class="count-text text-align-center">Goedgekeurde producten</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>40</span></h1> <p class="count-text text-align-center">Klinische studies tot nu toe</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>8</span></h1> <p class="count-text text-align-center">Jaar langste duur van blootstelling</p> </div> </div> <p class="text-center margin-top-24px"><em>Bijgewerkt per November 2023</em></p> </div> </div> </div> <div class=" popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-pop-up-field field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1441 paragraph--view-mode--default"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1441 paragraph--view-mode--default"> <div id="clp-full-bleed-bg" style="background: url(/sites/default/files/2022-01/cta_rnai_8.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:900px;margin:auto;"> <h1 class="text-align-center"><strong>RNAi: EEN REVOLUTIE IN DE BIOLOGIE, GEBASEERD OP NOBELPRIJS-WINNEND ONDERZOEK</strong></h1> <p class="text-align-center">RNA-interferentie (RNAi) is een doorbraak in het begrijpen hoe genen in cellen worden gereguleerd. Het vertegenwoordigt een volledig nieuwe benadering van het ontdekken en ontwikkelen van geneesmiddelen. De Nobelprijs voor de Fysiologie of Geneeskunde 2006, toegekend aan Craig Mello en Andrew Fire, bevestigt het belang van RNAi als een belangrijke wetenschappelijke ontdekking.</p> <p class="text-align-center"><a data-colorbox-inline=".cta-full-bleed-netherlands">Meer informatie ›</a></p> </div> <div class="cta-full-bleed-netherlands popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-pop-up-content field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">U WORDT NU DOORGESCHAKELD</h2> <h4>U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</h4> <p class="text-center"> <a class="button-more" href="/our-science/the-science-of-rnai" target= "_blank">DOORGAAN</a> </p> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1443 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:#f8f8f8;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h2 class="text-align-center"><strong>ONZE FOCUS</strong></h2> <p class="text-align-center">Onze pijplijn van RNAi-therapie onderzoek is gericht op ziekten met een onvervulde, hoge medische behoefte die onder 4 Strategische Therapeutische Gebieden vallen: genetische geneesmiddelen, cardiometabole aandoeningen, infectieziekten, en ziekten van het centraal zenuwstelsel (CZS) en oculaire ziekten.</p> <p class="text-align-center"> </p> <p class="text-align-center">Onze producten, goedgekeurd voor patiënten in de Europese Unie, behandelen erfelijke ATTR (hATTR) amyloïdose met polyneuropathie, acute hepatische porfyrie (AHP) en Primaire hyperoxalurie type 1 (PH1). Onze therapeutische kandidaat-producten in de late ontwikkelingsfase (fase 2 - fase 3) richten zich op erfelijke ATTR (hATTR) amyloïdose, hemofilie en zeldzame bloedingsaandoeningen, hypercholesterolemie en complement-gemedieerde ziekten.</p> </div> <div class=" popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-html-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> <div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-left-img-text paragraph-id--1445 paragraph--view-mode--default"> <div id="clp-left-img-text"> <div class="img-text-wrapper" style="width:1130px; margin:auto;"> <div class="img-box"> <div class="field field--name-field-upload-image field--type-image field--label-hidden field--item"> <img src="/sites/default/files/2023-11/Netherlands%202023%20Copy2x.png" width="1392" height="810" alt="" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div> </div> <div class="text-box"> <h2><strong>SLUIT U AAN BIJ ONS TEAM</strong></h2> <p>In ons streven om een commerciële organisatie te worden die zelfstandig medicijnen aan patiënten kan leveren, zoeken we mensen met verschillende vaardigheden, ervaringen en achtergronden om ons te helpen een team van wereldklasse op te bouwen. Wij zijn gevestigd in Cambridge in de Verenigde Staten, met kantoren in Zug (Zwitserland), Amsterdam (Nederland) en Maidenhead (Engeland), maar we werven personeel in heel Europa.</p> <p><a data-colorbox-inline=".cta-left-img-text-netherlands">Bekijk huidige vacatures (in het Engels) ›</a></p> </div> </div> <div class="cta-left-img-text-netherlands popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-clp-left-img-text-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">U WORDT NU DOORGESCHAKELD</h2> <h4>U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</h4> <p class="text-center"> <a class="button-more" href="http://jobs.alnylam.com/" target= "_blank">DOORGAAN</a> </p> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1447 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:#f8f8f8;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h1 class="text-align-center"><strong>CONTACT</strong></h1> <div class="row"> <div class="col-sm-6"> <h2 class="margin-top-0px">Alnylam Netherlands B.V.</h2> <p>Cross Towers, 20e verdieping<br /> Antonio Vivaldistraat 150<br /> 1083 HP Amsterdam<br /> Nederland</p> <p><a href="mailto:info@alnylam.nl">info@alnylam.nl</a><br /> <a href="tel:0800 403 0002">0800 403 0002</a> / <a href="tel:020 3697850">020 369 7850</a></p> </div> <div class="col-sm-6"> <p>Voor medische informatie, vragen over klinische studies, bijwerkingen en productklachten:</p> <p>Email: <a href="mailto:medinfo@alnylam.com">medinfo@alnylam.com</a><br /> Telefoon: <a href="tel:0800 282 0025 ">0800 282 0025</a> ook afgeschermde telefoonnummers <br /> <a href="tel:020 369 7861 ">020 369 7861</a></p> </div> </div> </div> <div class=" popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-html-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> <div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1449 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h2 class="text-align-center"><strong>RISICOMINIMALISATIE</strong></h2> <p>De risico minimalisatie materialen voor Patisiran zijn beordeeld door het College ter Beoordeling van Geneesmiddelen (CBG). Deze voorlichtingsmaterialen werden opgesteld om een veilige en duurzame toediening van patisiran thuis te verzekeren, in het streven om de belangrijke geidentificeerde risico's op infusie geïdentificeerde reacties (IRR's) te voorkomen en/of beperken.</p> <p> </p> <p><strong>Aanvragen van additionele risicominimalisatie-materialen</strong></p> <p>Exemplaren van de riscominimalisatie-materialen kunnen worden aagevraagd via telefoon op <a href="tel:08002820025">0800 282 0025</a> of <a href="tel:020 369 7861">020 369 7861</a>, of stuur een e-mail aan <a href="mailto:medinfo@alnylam.com">medinfo@alnylam.com</a>, of download de bestanden vanaf deze website.</p> <p class="text-align-center"> </p> <p>Informatie over Risicominimalisatie voor Patisiran:</p> <p>Voor zorgverleners <a href="/sites/default/files/2023-11/2023-05-Patisiran-Educational-material-for-HCP_NL-v3.pdf" target="_blank">(Download PDF)</a><br /> Voor patiënten <a href="/sites/default/files/2023-11/2023-05-Patisiran-Educational-material-for-patients_NL-v3.pdf" target="_blank">(Download PDF)</a></p> </div> <div class=" popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-html-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> <div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-callout-h1-cta paragraph-id--1451 paragraph--view-mode--default"> <div class="whole-clp-callout-h1-cta--component"> <div class="clp-callout-h1-cta--component" style="width:1130px; margin:auto; "> <div class="clp-callout-h1-cta-content col-sm-7"> <h2 class="clp-title-text"> <div class="field field--name-field-heading-1 field--type-string field--label-hidden field--item">MEER INFORMATIE OVER ALNYLAM</div> </h2> <div class="clp-callout-h1-cta-short-description"> <div class="field field--name-field-video-desc field--type-text-long field--label-hidden field--item"><p>Gedetailleerde informatie over onze wetenschap, onze pijplijn, voorzieningen voor medische professionals en patiënten en het laatste nieuws over Alnylam.</p> </div> </div> </div> <div class="clp-callout-h1-cta-link col-sm-5"> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><p><a data-colorbox-inline=".clp-callout-h1-netherlands">Bezoek onze internationale website ›</a></p> </div> </div> </div> <div class="clp-callout-h1-netherlands popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-h1-cta-popup-field field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">U WORDT NU DOORGESCHAKELD</h2> <h4>U verlaat www.alnylam.nl en gaat naar onze internationale, Engelstalige website (www.alnylam.com)</h4> <p class="text-center"> <a class="button-more" href="/" target= "_blank">DOORGAAN</a> </p> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1453 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h3>Deze website is alleen bedoeld voor inwoners van Nederland. Deze website is bedoeld om algemene informatie te geven over Alnylam voor inwoners van Nederland. Deze site wordt onderhouden door Alnylam, Alnylam is als enige verantwoordelijk voor de inhoud.</h3> <h3>Alnylam Netherlands B.V.</h3> <p>Corp-NLD-00017 November 2023</p> </div> <div class=" popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-html-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> <div> </div> </div> </div> <div class="field field--name-field-custom-page-lang field--type-string field--label-hidden field--item">nl</div> </div> </article> <section id="block-interstitialmodal" class="block block-block-content block-block-content91077066-95c8-4915-8931-1413e257836b clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"> <div class="modal" id="inter-modal" role="dialog" tabindex="-1"> <div class="inner" role="document"> <button aria-label="Close" class="close" data-dismiss="modal" type="button"></button> 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