CINXE.COM

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href="/about-alnylam/corporate-responsibility" class="sf-depth-2">Corporate Responsibility</a></li><li id="mobile-main-menu-menu-link-content2349be8e-3924-4327-95cd-599c456be6f5" class="sf-depth-2 sf-no-children"><a href="/about-alnylam/diversity-inclusion" class="sf-depth-2">Diversity, Equity & Inclusion</a></li><li id="mobile-main-menu-menu-link-content369c2613-4f95-495f-b97d-7fe7704c1281" class="sf-depth-2 sf-no-children"><a href="https://investors.alnylam.com/press-releases" class="sf-depth-2 sf-external">Press Releases</a></li><li id="mobile-main-menu-menu-link-content9624843b-3ef8-4260-97fc-4719352453f5" class="sf-depth-2 sf-no-children"><a href="https://capella.alnylam.com/our-science/capella-rnai-innovation/" class="sf-depth-2 sf-external">Capella (Scientific Presentations)</a></li><li id="mobile-main-menu-menu-link-content8852cdce-87dc-4c88-be02-219bdc7a435f" class="sf-depth-2 sf-no-children"><a href="https://www.rnaiscience.com/" class="sf-depth-2 sf-external" target="_blank">Medical Resources (RNAi Science)</a></li><li id="mobile-main-menu-menu-link-content54fe53ea-8cc4-4734-9e8b-b9e23b3774a0" class="sf-depth-2 sf-no-children"><a href="/contact-us" class="sf-depth-2">Contact Us</a></li></ul></li> </ul> </section> </div> </div> <div class="mobile-header-logo"> <div class="region region-mobile-logo"> <a class="logo navbar-btn pull-left" href="/" title="Home" rel="home"> <img src="/themes/custom/alnylam/logo.svg" alt="Home" /> </a> </div> </div> <div class="mobile-header-search"> <div class="region region-mobile-search"> <section id="block-basicsearchblock-2" class="block block-alnylam-search block-basic-search-block clearfix"> <div class="alnylam__basic-search-block"> <form action="/search-results" method="GET"> <div class="search-input input-group hide"> <input type="text" name="keyword" placeholder="Type something"/> <button type="submit">search</button> </div> <button type="button" class="search-open-btn"><img 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paragraph--type--language-links paragraph-id--107 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Global</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--108 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Austria</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-austria">Deutsch</a></div> </div> </span> </div> </div> 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href="/alnylam-belgium-dutch"> Nederlands</a></div> <div class="field--item"><a href="/alnylam-belgium-french">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--109 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Luxembourg</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-luxembourg-french">Français</a></div> <div class="field--item"><a href="/alnylam-luxembourg-german"> Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--112 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Brazil </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.com.br/">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--111 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Netherlands </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-netherlands">Nederlands</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--114 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Canada </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.ca/fr">Français </a></div> <div class="field--item"><a href="https://www.alnylam.ca/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--113 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Portugal</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-portugal">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1513 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Czech Republic</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-czech-republic">Čeština</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--115 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Spain </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-espana">Español</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--116 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Denmark </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-denmark">Dansk</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--117 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Sweden</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-sverige">Svenska</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--118 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">France</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.fr/">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--119 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Switzerland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-switzerland-french">Français</a></div> <div class="field--item"><a href="/alnylam-switzerland-german">Deutsch</a></div> <div class="field--item"><a href="/alnylam-switzerland-italian">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--120 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Germany </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.de/">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--121 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taiwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">繁體中文</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1514 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Ireland </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-ireland">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--123 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">United Kingdom</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--122 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Italy</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.it/">Italiano</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> </div> <div id="whole-header-top" class="container-fluid"> <div class="header-top-left col-sm-2"> <div class="region region-header-top-left"> <a class="logo navbar-btn pull-left" href="/" title="Home" rel="home"> <img src="/themes/custom/alnylam/logo.svg" alt="Home" /> </a> </div> </div> <div class="header-top-middle col-sm-9"> <div class="region region-header-top-middle"> <section id="block-alnylam-topnavigation-3" class="block block-superfish block-superfishtop-navigation clearfix"> <ul id="superfish-top-navigation" class="menu sf-menu sf-top-navigation sf-horizontal sf-style-none"> <li id="top-navigation-menu-link-content64f38306-897f-4a7c-99eb-affe953acf01" class="sf-depth-1 menuparent"><span class="sf-depth-1 menuparent nolink">Investors</span><ul><li id="top-navigation-menu-link-content0099a821-634f-457b-bfed-bba6d6235d4f" class="sf-depth-2 sf-no-children"><a href="https://investors.alnylam.com/" class="sf-depth-2 sf-external">For Investors</a></li><li id="top-navigation-menu-link-contente1e1fcab-d6cb-4681-aec8-647dac1fe8f2" class="sf-depth-2 sf-no-children"><a href="https://investors.alnylam.com/alny-stock-information" class="sf-depth-2 sf-external">Stock Information</a></li><li id="top-navigation-menu-link-content37980c4c-fa7d-430a-9bb6-13addbb93796" class="sf-depth-2 sf-no-children"><a href="https://investors.alnylam.com/investor-toolkit" class="sf-depth-2 sf-external">Investors Toolkit</a></li><li id="top-navigation-menu-link-content8f5bcff2-d5da-45e2-b6df-8bb846a4edc4" class="sf-depth-2 sf-no-children"><a href="https://investors.alnylam.com/events" class="sf-depth-2 sf-external">Events & Presentations</a></li><li 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class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Luxembourg</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-luxembourg-french">Français</a></div> <div class="field--item"><a href="/alnylam-luxembourg-german"> Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--112 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Brazil </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.com.br/">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--111 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Netherlands </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-netherlands">Nederlands</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--114 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Canada </div> </span><span class="link-text"> <div class="field 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<div class="field field--name-field-label field--type-string field--label-hidden field--item">Czech Republic</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-czech-republic">Čeština</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--115 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Spain </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-espana">Español</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--116 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class="paragraph paragraph--type--language-links paragraph-id--118 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">France</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.fr/">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--119 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Switzerland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-switzerland-french">Français</a></div> <div class="field--item"><a href="/alnylam-switzerland-german">Deutsch</a></div> <div class="field--item"><a href="/alnylam-switzerland-italian">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--120 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Germany </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.de/">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--121 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taiwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">繁體中文</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1514 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Ireland </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-ireland">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--123 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">United Kingdom</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--122 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Italy</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.it/">Italiano</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> </div> </header> <div id="maindiv" class="container-fluid"> <main id="midcontent-area" class="column main-content"> <div id="content"> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <article data-history-node-id="80" role="article" about="/node/80" typeof="schema:WebPage" class="page full clearfix"> <span property="schema:name" content="Alnylam® Pharmaceuticals" class="hidden"></span> <div class="content"> <div class="field field--name-field-add-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--add-block paragraph-id--322 paragraph--view-mode--default"> <div class="addblock--component" id="cr-in-action" style="width:px; margin:auto; "> <div class="field field--name-field-add-block field--type-block-field field--label-hidden field--item"><section class="views-element-container block block-views block-views-blockbanner-slideshow-block-1 clearfix" id="block-views-block-banner-slideshow-block-1"> <div class="form-group"><div class="view view-banner-slideshow view-id-banner_slideshow view-display-id-block_1 js-view-dom-id-57579d85622b9accb6e324f090344fe4022fbfae18bf3bd4dd5f59786b184ba0"> <div class="view-content"> <div data-settings="{"grouping":[],"row_class":"","default_row_class":true,"uses_fields":false,"items":1,"itemsDesktop":[1199,4],"itemsDesktopSmall":[979,3],"itemsTablet":[768,2],"itemsMobile":[479,1],"singleItem":true,"itemsScaleUp":false,"slideSpeed":200,"paginationSpeed":800,"rewindSpeed":1000,"autoPlay":true,"stopOnHover":true,"navigation":true,"navigationText":["prev","next"],"prevText":"prev","nextText":"next","rewindNav":true,"scrollPerPage":false,"pagination":true,"paginationNumbers":false,"responsive":true,"responsiveRefreshRate":200,"mouseDrag":true,"touchDrag":true,"transitionStyle":"fade"}" class="owl-slider-wrapper owl-carousel"> <div><div class="views-field views-field-edit-node"><span class="field-content"></span></div><div class="views-field views-field-field-banner-image"><div class="field-content desktop-banner"> <picture> <source srcset="/sites/default/files/styles/hero_image/public/2024-05/hero%402x.png?itok=ULgLBOzf 1x" media="all and (min-width: 851px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_tablet/public/2024-05/hero%402x.png?itok=GArxasLl 1x" media="all and (min-width: 560px) and (max-width: 850px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_mobile/public/2024-05/hero%402x.png?h=bacb0731&itok=gLNO8K9C 1x" type="image/png"/> <img src="/sites/default/files/styles/hero_image/public/2024-05/hero%402x.png?itok=ULgLBOzf" alt="" typeof="foaf:Image" class="img-responsive" /> </picture> </div></div><div class="views-field views-field-field-mobile-banner-image"><div class="field-content mobile-banner"> <img src="/sites/default/files/2024-05/corp-responsibility.png" width="375" height="681" alt="Disease Disrupted" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-field-ipad-banner-image"><div class="field-content"> <img src="/sites/default/files/2024-05/group-13_0_0.png" width="1280" height="680" alt="" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-nothing"><span class="field-content"><div class="banner-slideshow-overlay-content container"> <div class="description our-company"><h2>Disrupting Disease<span>™</span></h2> <p>Alnylam’s RNAi therapeutics silence the genes that cause or contribute to disease</p> </div> <div class="cta-button"><a href="/about-alnylam">Learn How ›</a></div> </div></span></div></div> <div><div class="views-field views-field-edit-node"><span class="field-content"></span></div><div class="views-field views-field-field-banner-image"><div class="field-content desktop-banner"> <picture> <source srcset="/sites/default/files/styles/hero_image/public/2022-02/group-4%402x.png?itok=DQ3cIxIk 1x" media="all and (min-width: 851px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_tablet/public/2022-02/group-4%402x.png?itok=AYh41Yuj 1x" media="all and (min-width: 560px) and (max-width: 850px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_mobile/public/2022-02/group-4%402x.png?h=3c24a763&itok=lCPgR-C9 1x" type="image/png"/> <img src="/sites/default/files/styles/hero_image/public/2022-02/group-4%402x.png?itok=DQ3cIxIk" alt="Pioneered Here" typeof="foaf:Image" class="img-responsive" /> </picture> </div></div><div class="views-field views-field-field-mobile-banner-image"><div class="field-content mobile-banner"> <img src="/sites/default/files/2022-01/Pioneered-here.png" width="375" height="682" alt="Pioneered Here" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-field-ipad-banner-image"><div class="field-content"> <img src="/sites/default/files/2024-05/group-4_2.png" width="1280" height="681" alt="Pioneered Here" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-nothing"><span class="field-content"><div class="banner-slideshow-overlay-content container"> <div class="description our-science"><h2>Pioneered Here</h2> <p>Alnylam’s pioneering work in RNAi has created this innovative new class of medicines</p> </div> <div class="cta-button"><a href="/our-science/the-science-of-rnai">Learn How ›</a></div> </div></span></div></div> <div><div class="views-field views-field-edit-node"><span class="field-content"></span></div><div class="views-field views-field-field-banner-image"><div class="field-content desktop-banner"> <picture> <source srcset="/sites/default/files/styles/hero_image/public/2024-03/patient-people-first.png?itok=Gblre_vT 1x" media="all and (min-width: 851px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_tablet/public/2024-03/patient-people-first.png?itok=wnaCydJP 1x" media="all and (min-width: 560px) and (max-width: 850px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_mobile/public/2024-03/patient-people-first.png?h=1cca938c&itok=WGpSXLl_ 1x" type="image/png"/> <img src="/sites/default/files/styles/hero_image/public/2024-03/patient-people-first.png?itok=Gblre_vT" alt="people-first" typeof="foaf:Image" class="img-responsive" /> </picture> </div></div><div class="views-field views-field-field-mobile-banner-image"><div class="field-content mobile-banner"> <img src="/sites/default/files/2024-03/people-first1.png" width="1125" height="2043" alt="people-first" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-field-ipad-banner-image"><div class="field-content"> <img src="/sites/default/files/2024-05/group-7.png" width="1280" height="680" alt="people-first" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-nothing"><span class="field-content"><div class="banner-slideshow-overlay-content container"> <div class="description secondary-dark"><h2>People First</h2> <p>Whether they’re patients, or members of our communities, people are at the center of all we do</p> </div> <div class="cta-button"><a href="/about-alnylam/corporate-responsibility">Learn More ›</a></div> </div></span></div></div> <div><div class="views-field views-field-edit-node"><span class="field-content"></span></div><div class="views-field views-field-field-banner-image"><div class="field-content desktop-banner"> <picture> <source srcset="/sites/default/files/styles/hero_image/public/2024-04/our-pipeline_0.png?itok=WVLTUhhC 1x" media="all and (min-width: 851px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_tablet/public/2024-04/our-pipeline_0.png?itok=UHyVfgLw 1x" media="all and (min-width: 560px) and (max-width: 850px)" type="image/png"/> <source srcset="/sites/default/files/styles/hero_image_for_mobile/public/2024-04/our-pipeline_0.png?h=1cca938c&itok=7O4Qfg0i 1x" type="image/png"/> <img src="/sites/default/files/styles/hero_image/public/2024-04/our-pipeline_0.png?itok=WVLTUhhC" alt="Broad Impact" typeof="foaf:Image" class="img-responsive" /> </picture> </div></div><div class="views-field views-field-field-mobile-banner-image"><div class="field-content mobile-banner"> <img src="/sites/default/files/2024-04/brod-impact.png" width="1125" height="2043" alt="Broad Impact" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-field-ipad-banner-image"><div class="field-content"> <img src="/sites/default/files/2024-05/group-10.png" width="1280" height="680" alt="Broad Impact" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div></div><div class="views-field views-field-nothing"><span class="field-content"><div class="banner-slideshow-overlay-content container"> <div class="description our-science"><h2>Broad Impact</h2> <p>Moving beyond just rare diseases, we aim to improve the lives of millions</p> </div> <div class="cta-button"><a href="/alnylam-rnai-pipeline">OUR PIPELINE ›</a></div> </div></span></div></div> </div> </div> </div> </div> </section> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--html-content-with-background paragraph-id--326 paragraph--view-mode--default"> <div class="html-content-background " style="width:px; background-color: #f4f9fc ;"> <div class="row inner-block" "> <div class="field field--name-field-html-content-bg field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--body paragraph-id--325 paragraph--view-mode--default"> <div class="description--component" style="width:970px; margin:auto; "> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><h1 class="our-company">THE LEADING RNAi THERAPEUTICS COMPANY</h1> <p class="font-20">Alnylam’s pioneering science has yielded the critical breakthroughs and innovations that have made RNA interference (RNAi)-based medicines a reality.</p> <p class="font-20 mb-32">We ushered in the first phase of the RNAi Revolution<sup class="custom-sup">TM</sup> by developing the first five approved RNAi therapeutics. Now, we’re pioneering what’s next, working to bring RNAi therapeutics to a broad spectrum of difficult-to-treat diseases, both rare and which impact millions of people around the world.</p> <p class="text-align-center desktop-mt-32"><a class="dark-button-more" href="/about-alnylam">MORE ABOUT ALNYLAM ›</a></p> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--html-content-with-background paragraph-id--2124 paragraph--view-mode--default"> <div class="html-content-background silencing-genes" style="width:px; background-color: #00254b ;"> <div class="row inner-block" "> <div class="field field--name-field-html-content-bg field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--body paragraph-id--2123 paragraph--view-mode--default"> <div class="description--component" style="width:970px; margin:auto; "> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><h2 class="our-science">Silencing genes to disrupt disease</h2> <div class="imgg-conntainer"><img class="img-blury-t" loading="eager" src="/sites/default/files/inline-images/gradient.svg" /><div class="imgg-conn"> <video autoplay="" id="vid" loop="" muted="" playsinline="" width="100%"><source src="/sites/default/files/videos/moasnippet.mp4" type="video/mp4"></source><source src="/sites/default/files/videos/moasnippet.mp4" type="video/ogg"></source></video></div> <img class="img-blury-b" loading="eager" src="/sites/default/files/inline-images/gradient-copy.svg" /></div> <div class="conntent d-flex justify-content-between align-item-end"> <div class="text-con"> <p class="mb-24">RNA interference (RNAi) is a naturally occurring process already at work inside your body which regulates how genes make new proteins. Proteins play a critical role in almost everything your body does, but sometimes, they can cause or contribute to disease. Our medicines leverage the RNAi process to prevent specific proteins from being made, disrupting disease at its source.</p> <p>We believe that this revolutionary approach can be used to silence virtually any gene in the genome… meaning that the diseases we’re treating today are just the beginning of what’s possible.</p> </div> <div class="button-cons"><a href="/our-science/the-science-of-rnai">MORE ABOUT RNAi ›</a></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--body paragraph-id--324 paragraph--view-mode--default"> <div class="description--component" style="width:1108px; margin:auto; "> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><div id="our-science-homepage"> <h2 class="our-science mt-0">OUR PIPELINE</h2> <p class="font-20 margin-bottom-32px">Our robust pipeline of investigational RNAi therapeutics is currently focused on diseases with high unmet medical need, including transthyretin amyloidosis, rare diseases, cardiovascular diseases, metabolic diseases, and neurological diseases. Additionally, we will always follow the science and are continually looking for new disease targets that may benefit from our RNAi technology.</p> <div class="d-none row text-center"> <div class="col-sm-3"> <div class="genetic-medicines circle-icon-box"> </div> <p class="image-title">Genetic Medicines</p> </div> <div class="col-sm-3"> <div class="cardio-metabolic-medicine circle-icon-box"> </div> <p class="image-title">Cardio-Metabolic Diseases</p> </div> <div class="col-sm-3"> <div class="infectious-disease circle-icon-box"> </div> <p class="image-title">Infectious Diseases</p> </div> <div class="col-sm-3"> <div class="central-nervous-system circle-icon-box"> </div> <p class="image-title">Central Nervous System & Ocular Diseases</p> </div> </div> <p class="text-align-center desktop-mt-32"><a class="dark-button-more" href="/alnylam-rnai-pipeline">EXPLORE OUR PIPELINE ›</a></p> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--body paragraph-id--1580 paragraph--view-mode--default"> <div class="description--component" style="width:px; margin:auto; "> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><div class="whole-patient-comes-first-section" style="background:#00254b;"> <div class="content"> <div class="description"> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item" data-quickedit-field-id="paragraph/327/field_body/en/default"> <h2 class="secondary-light">PATIENTS COME FIRST</h2> <div class="row"> <div class="col-sm-9"> <p class="font-20">While we’re driven by science, we’re motivated by people because for us, this is personal. Whether we're working to develop the first treatment for a disease or a better one, patients are the center of all we do. They are the reason we come to work every day, and their stories inspire us to continue to innovate by pushing the science of RNAi therapeutics forward.</p> </div> <div class="col-sm-3"> <p><a class="button-more" href="/patients">LEARN MORE ›</a></p> </div> </div> </div> </div> </div> <div class="image-quote overlap"> <div class="image"> <div class="field field--name-field-upload-image field--type-image field--label-hidden field--item" data-quickedit-field-id="paragraph/327/field_upload_image/en/default"><img alt="" class="img-responsive" height="561" loading="lazy" src="/sites/default/files/2022-02/group-4_0.png" typeof="foaf:Image" width="1170" /></div> </div> <div class="quote"> <div class="field field--name-field-qutote field--type-text-long field--label-hidden field--item" data-quickedit-field-id="paragraph/327/field_qutote/en/default"> <p class="quote-text">My body started to warn me that something was wrong. That I had a problem… My father passed away 40 years ago; after I received my diagnosis, we believe what he really had was hATTR amyloidosis like me.</p> <p class="text-align-right"><span>-Chen, living with hATTR amyloidosis</span></p> </div> </div> <div class="cboxElement" data-colorbox-inline=".patients-comes-first-video-home"> <div class="three-column-video-play-button"> </div> </div> <div class="patients-comes-first-video-home" style="display: none;"> <div class="field field--name-field-embed-video field--type-video-embed-field field--label-hidden field--item" data-once="quickedit" data-quickedit-field-id="paragraph/464/field_embed_video/en/default"> <div class="video-embed-field-provider-youtube video-embed-field-responsive-video form-group"><iframe allowfullscreen="allowfullscreen" data-gtm-yt-inspected-6886893_103="true" frameborder="0" height="480" id="566659760" src="https://www.youtube.com/embed/gDsiBYMS7gY?start=0&rel=0" width="854"></iframe></div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--add-block paragraph-id--412 paragraph--view-mode--default"> <div class="addblock--component" id="cr-in-action" style="width:1170px; margin:auto; "> <div class="field field--name-field-add-block field--type-block-field field--label-hidden field--item"><section class="views-element-container block block-views block-views-blocknews-block-1 clearfix" id="block-views-block-news-block-1"> <div class="form-group"><div class="view view-news view-id-news view-display-id-block_1 js-view-dom-id-0e9761fcbe8cd1fff271d0e6c28d162fe7ed21ca390ba279211565566e53afa7"> <div class="view-header"> <div class="news heading"> <div class="row"> <div class="col-sm-7"><h2 class="our-news">ALNYLAM NEWS</h2></div> <div class="col-sm-5"><div class="news-right"></div><div class="mobile-newsroom"><a href="https://news.alnylam.com/" class="dark-button-more">VISIT THE NEWSROOM ›</a></div></div> </div> </div> </div> <div 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data-src="/sites/default/files/2024-10/Science-2024-blue.png" src="data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E" width="1410" height="867" typeof="foaf:Image" /> </div> </div> <div class="slide__caption"> <div class="slide__description"><div class="views-field views-field-nothing"><span class="field-content"><div class="news-box"> <h5>Alnylam Named a Top Science Employer by Science Magazine</h5> <div class="description-text">This is our 6th consecutive year on the Science Magazine Top Employer list </div> <div class="view-article-btn"><a href="https://news.alnylam.com/careers-culture/articles/driven-science-alnylam-named-science-magazine-top-employer-6-years-row">view article ›</a></div> </div></span></div></div> </div> </div> </div> <div class="slick__slide slide slide--1"> <div class="slide__content"> <div class="slide__media"> <div style="padding-bottom: 61.6%;" data-ratio="61.6" class="media media--blazy 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href="https://investors.alnylam.com/press-release?id=28231">view article ›</a></div> </div></span></div></div> </div> </div> </div> <div class="slick__slide slide slide--3"> <div class="slide__content"> <div class="slide__media"> <div style="padding-bottom: 48.32%;" data-ratio="48.32" class="media media--blazy media--slick media--image media--ratio media--ratio--fluid is-b-loading"><img alt="our-commitment-to-patient-access" class="media__image media__element b-lazy img-responsive" decoding="async" loading="lazy" data-src="/sites/default/files/2024-09/our-commitment-to-patient-access-1.png" src="data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E" width="656" height="317" typeof="foaf:Image" /> </div> </div> <div class="slide__caption"> <div class="slide__description"><div class="views-field views-field-nothing"><span class="field-content"><div class="news-box"> <h5>Our Commitment to Patient Access</h5> <div 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class="slide__description"><div class="views-field views-field-nothing"><span class="field-content"><div class="news-box"> <h5>Alnylam Ranked #3 on LinkedIn's List of Top Midsize Companies</h5> <div class="description-text">We are honored to be recognized for our commitment to employee career growth. </div> <div class="view-article-btn"><a href="https://news.alnylam.com/careers-culture/articles/alnylam-ranked-3-linkedins-list-top-midsize-companies-2024">view article ›</a></div> </div></span></div></div> </div> </div> </div> <div class="slick__slide slide slide--5"> <div class="slide__content"> <div class="slide__media"> <div style="padding-bottom: 61.49%;" data-ratio="61.49" class="media media--blazy media--slick media--image media--ratio media--ratio--fluid is-b-loading"><img alt="Corporate Responsibility at Alnylam" class="media__image media__element b-lazy img-responsive" decoding="async" loading="lazy" data-src="/sites/default/files/2024-05/corporate-responsibility-report-2023_0.png" src="data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E" width="940" height="578" typeof="foaf:Image" /> </div> </div> <div class="slide__caption"> <div class="slide__description"><div class="views-field views-field-nothing"><span class="field-content"><div class="news-box"> <h5>Corporate Responsibility at Alnylam</h5> <div class="description-text">We’ve published our fourth annual Corporate Responsibility Report </div> <div class="view-article-btn"><a href="https://news.alnylam.com/responsibility/articles/alnylam-publishes-2023-corporate-responsibility-report ">view article ›</a></div> </div></span></div></div> </div> </div> </div> <div class="slick__slide slide slide--6"> <div class="slide__content"> <div class="slide__media"> <div style="padding-bottom: 61.49%;" data-ratio="61.49" class="media media--blazy media--slick 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