CINXE.COM

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site international d’Alnylam (en anglais) ›</a></p> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-belgium-french popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">REDIRECTION EN COURS</h2> <p class="text-align-center">Vous quittez le site www.alnylam.be et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</p> <p class="text-align-center"><a class="button-more text-center" href="/">CONTINUER</a></p> </div> </div> </div> </section> </div> </div> </div> </div> <div id="clp-whole-header-top" class="container-fluid"> <div class="site-branding-menu-wrapper .row"> <div class="col-sm-4 site-branding"> <div class="clp-header-top_left"> <div class="region region-clp-header-top-left"> <section id="block-clplogo" class="block block-block-content block-block-contentbb568d43-f6bc-492d-b5aa-ecead699fbce clearfix"> <div class="field field--name-body 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class="cta-header-secondary-menu-Investisseurs popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">REDIRECTION EN COURS</h2> <p class="text-align-center">Vous quittez le site www.alnylam.be et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</p> <p class="text-align-center"><a class="button-more text-center" href="https://investors.alnylam.com/">CONTINUER</a></p> </div> </div> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-Carrières popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">REDIRECTION EN COURS</h2> <p class="text-align-center">Vous quittez le site www.alnylam.be et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</p> <p class="text-align-center"><a class="button-more text-center" href="/careers/">CONTINUER</a></p> </div> </div> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-TRANSPARENCE popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">REDIRECTION EN COURS</h2> <p class="text-align-center">Vous quittez le site www.alnylam.be et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</p> <p class="text-align-center"><a class="button-more text-center" href="/about-alnylam/transparency">CONTINUER</a></p> </div> </div> </div> </section> <section id="block-language-4" class="block block-block-content block-block-content5a7dc698-6efe-4c02-a3cd-adb2377d4faf clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><div class="language block" id="language-switcher-icon">language<i class="fas fa-angle-down"></i></div> </div> </section> </div> </div> </div> <div class="row ext-cta"> <div class="clp-header-right-bottom"> <div class="region region-clp-header-right-bottom"> <section id="block-clpheaderblockforbelgiumfrench" class="block block-block-content block-block-contentf5027818-a1c2-4af6-b518-d0e7363de720 clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p><a data-colorbox-inline=".cta-header-belgium-french">Visiter le site international d’Alnylam (en anglais) ›</a></p> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-belgium-french popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">REDIRECTION EN COURS</h2> <p class="text-align-center">Vous quittez le site www.alnylam.be et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</p> <p class="text-align-center"><a class="button-more text-center" href="/">CONTINUER</a></p> </div> </div> </div> </section> </div> </div> </div> <div class="clp-language-switcher-block-wrapper"> <div class="clp-language-switcher-block"> <div class="region region-clp-header-language-block"> <section id="block-languageswitcherforclpbelgiumfrench-2" class="block block-block-content block-block-contentac339d31-ce27-417c-a7da-186c0c3256a5 clearfix"> <div class="field field--name-field-language-link field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--717 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Global</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--718 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Autriche</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-austria">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--719 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Belgique</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-belgium-dutch">Nederlands</a></div> <div class="field--item"><a href="/alnylam-belgium-french">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--720 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Brésil</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.com.br/">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--721 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Canada</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.ca/fr">Français</a></div> <div class="field--item"><a href="https://www.alnylam.ca/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--722 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">République tchèque</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-czech-republic">Čeština</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--723 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Danemark</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-denmark">Dansk</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--724 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">France </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.fr/">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--725 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Allemagne</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.de/">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--726 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Irlande</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-ireland">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--727 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Italie</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.it/">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--728 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Japon</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.jp/">Japanese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--729 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Luxembourg</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-luxembourg-french">Français</a></div> <div class="field--item"><a href="/alnylam-luxembourg-german">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--730 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Pays-Bas</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-netherlands">Nederlands</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--731 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Portugal</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-portugal">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--732 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Espagne</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-espana">Español</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--733 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Suède</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-sverige">Svenska</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--734 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Suisse</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-switzerland-french">Français</a></div> <div class="field--item"><a href="/alnylam-switzerland-german">Deutsch</a></div> <div class="field--item"><a href="/alnylam-switzerland-italian">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--735 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taïwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">Traditional Chinese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--736 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Royaume-Uni</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> </div> </div> </div> </header> <div id="maindiv" class="container-fluid"> <main id="midcontent-area" class="column main-content"> <div id="content"> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <article data-history-node-id="667" role="article" about="/alnylam-belgium-french" class="clp full clearfix"> <div class="content"> <div class="field field--name-field-add-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1202 paragraph--view-mode--default"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1202 paragraph--view-mode--default"> <div id="simple-banner-with-text-wrapper" style="background: url(/sites/default/files/2022-04/header_slider_belgium_french_2.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:1130px;margin:auto;"> <div class="upper-text"> <h2>À ceux qui déclarent que c’est « impossible, illusoire ou irréaliste, » nous répondons que nous</h2> <h1>Relevons Le Défi</h1> <p>Nous développons actuellement une nouvelle classe innovante de médicaments appelés traitements ARNi qui, selon nous, peuvent potentiellement transformer la vie des personnes atteintes de maladies rares.</p> </div> </div> </div> <div class="mobile-upper-text"> <h2>À ceux qui déclarent que c’est « impossible, illusoire ou irréaliste, » nous répondons que nous</h2> <h1>Relevons Le Défi</h1> <p>Nous développons actuellement une nouvelle classe innovante de médicaments appelés traitements ARNi qui, selon nous, peuvent potentiellement transformer la vie des personnes atteintes de maladies rares.</p> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-banner-overlay paragraph-id--1204 paragraph--view-mode--default"> <div id="clp-banner-overlay"> <div class="banner-text-wrapper" style="width:1130px; margin:auto;"> <div class="text-box"> <section> <h1 class="text-align-center"><strong>À L’AVANT-GARDE</strong></h1> <p class="text-align-center">Alnylam conduit la transformation de l’ARN interférence (ARNi) en une nouvelle classe innovante de médicaments destinés à des patients disposant d’options de traitement limitées ou inadaptées. Basés sur des données scientifiques récompensées d’un Prix Nobel, les traitements ARNi constituent une approche pour le traitement d'un large éventail de maladies graves et invalidantes.</p> <p class="text-align-center">Créée en 2002, la société Alnylam concrétise une vision audacieuse selon laquelle des possibilités scientifiques peuvent devenir une réalité en s’appuyant sur une solide plateforme de découverte et un large portefeuille de médicaments expérimentaux.</p> </section> </div> </div> <div class=" popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-pop-up-field field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1206 paragraph--view-mode--default"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1206 paragraph--view-mode--default"> <div id="clp-full-bleed-bg" style="background: url(/sites/default/files/2022-01/cta_rnai_0.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:900px;margin:auto;"> <h2 class="text-align-center"><strong>ARNi : UNE INNOVATION DANS LE DOMAINE DE LA BIOLOGIE QUI S’APPUIE SUR DES RECHERCHES RÉCOMPENSÉES PAR UN PRIX NOBEL</strong></h2> <p class="text-align-center">L’ARN interférence (ARNi) constitue une percée dans la compréhension de la façon dont les gènes sont régulés dans les cellules. C’est également une approche totalement nouvelle appliquée à la découverte et au développement de médicaments. Le Prix Nobel 2006 de physiologie ou de médecine, décerné à Craig Mello et Andrew Fire, a reconnu l’importance de l’ARNi comme une découverte scientifique majeure.</p> <p class="text-align-center"><a data-colorbox-inline=".cta-full-bleed-belgium-french">En savoir plus ›</a></p> </div> <div class="cta-full-bleed-belgium-french popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-pop-up-content field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">REDIRECTION EN COURS</h2> <h4>Vous quittez le site www.alnylam.be et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</h4> <p class="text-center"> <a class="button-more" href="/our-science/the-science-of-rnai" target= "_blank">CONTINUER</a> </p> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1208 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:#f8f8f8;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h2 class="text-align-center"><strong>NOTRE PRIORITÉ</strong></h2> <p class="text-align-center">L’ensemble de nos traitements RNAi expérimentaux visent à traiter des maladies dont les besoins médicaux ne sont pas satisfaits et qui s’inscrivent dans le cadre de 4 domaines thérapeutiques stratégiques (STArs, Strategic Therapeutic Areas) : médicaments génétiques, maladies cardio-métaboliques, maladies infectieuses et maladies du système nerveux central (SNC) et oculaires.</p> <p class="text-align-center">Nos produits approuvés à l’intention des patients dans l’Union européenne traitent l'amylose héréditaire à transthyrétine (hATTR) avec polyneuropathie, la porphyrie hépatique aiguë de type 1 (PH1), et l'hyperoxalurie primitive (HP). Nos produits thérapeutiques ayant atteint un stade avancé (Phase 2 - Phase 3) de développement se concentrent sur le traitement des amyloses TTR héréditaires (hATTR), de l’hémophilie et des troubles rares de la coagulation, et des maladies liées à un déficit en complément.</p> </div> <div class=" popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-html-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> <div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-left-img-text paragraph-id--1210 paragraph--view-mode--default"> <div id="clp-left-img-text"> <div class="img-text-wrapper" style="width:1130px; margin:auto;"> <div class="img-box"> <div class="field field--name-field-upload-image field--type-image field--label-hidden field--item"> <img src="/sites/default/files/2024-09/bl_0.jpg" width="2088" height="1215" alt="bl" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div> </div> <div class="text-box"> <h2><strong>REJOINDRE NOTRE ÉQUIPE</strong></h2> <p>Alors que nous nous efforçons d’atteindre notre but, à savoir devenir une entreprise commerciale pouvant fournir des médicaments aux patients de façon indépendante, nous recherchons des personnes possédant des compétences, expériences, origines et cultures diverses pour nous aider à créer une équipe de classe internationale. 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