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生物物理化学 - 维基百科,自由的百科全书

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</div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading" lang="zh-Hans-MY" dir="ltr"><span class="mw-page-title-main">生物物理化学</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" lang="zh-Hans-MY" dir="ltr"> <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。18种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-18" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">18种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%83%D9%8A%D9%85%D9%8A%D8%A7%D8%A1_%D9%81%D9%8A%D8%B2%D9%8A%D8%A7%D8%A6%D9%8A%D8%A9_%D8%AD%D9%8A%D9%88%D9%8A%D8%A9" title="كيمياء فيزيائية حيوية – 阿拉伯语" lang="ar" hreflang="ar" data-title="كيمياء فيزيائية حيوية" data-language-autonym="العربية" data-language-local-name="阿拉伯语" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%91%D0%B8%D0%BE%D1%84%D0%B8%D0%B7%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0_%D1%85%D0%B8%D0%BC%D0%B8%D1%8F" title="Биофизическа химия – 保加利亚语" lang="bg" hreflang="bg" data-title="Биофизическа химия" data-language-autonym="Български" data-language-local-name="保加利亚语" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Biofyzik%C3%A1ln%C3%AD_chemie" title="Biofyzikální chemie – 捷克语" lang="cs" hreflang="cs" data-title="Biofyzikální chemie" data-language-autonym="Čeština" data-language-local-name="捷克语" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Biophysikalische_Chemie" title="Biophysikalische Chemie – 德语" lang="de" hreflang="de" data-title="Biophysikalische Chemie" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Biophysical_chemistry" title="Biophysical chemistry – 英语" lang="en" hreflang="en" data-title="Biophysical chemistry" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Biofisicoqu%C3%ADmica" title="Biofisicoquímica – 西班牙语" lang="es" hreflang="es" data-title="Biofisicoquímica" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%B4%DB%8C%D9%85%DB%8C%E2%80%8C%D9%81%DB%8C%D8%B2%DB%8C%DA%A9_%D8%B2%DB%8C%D8%B3%D8%AA%DB%8C" title="شیمی‌فیزیک زیستی – 波斯语" lang="fa" hreflang="fa" data-title="شیمی‌فیزیک زیستی" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Kimia_biofisika" title="Kimia biofisika – 印度尼西亚语" lang="id" hreflang="id" data-title="Kimia biofisika" data-language-autonym="Bahasa Indonesia" data-language-local-name="印度尼西亚语" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6" title="生物物理化学 – 日语" lang="ja" hreflang="ja" data-title="生物物理化学" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%83%9D%EB%AC%BC%EB%AC%BC%EB%A6%AC%ED%99%94%ED%95%99" title="생물물리화학 – 韩语" lang="ko" hreflang="ko" data-title="생물물리화학" data-language-autonym="한국어" data-language-local-name="韩语" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Biof%C3%ADsica_qu%C3%ADmica" title="Biofísica química – 葡萄牙语" lang="pt" hreflang="pt" data-title="Biofísica química" data-language-autonym="Português" data-language-local-name="葡萄牙语" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Chimie_biofizic%C4%83" title="Chimie biofizică – 罗马尼亚语" lang="ro" hreflang="ro" data-title="Chimie biofizică" data-language-autonym="Română" data-language-local-name="罗马尼亚语" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Biofizi%C4%8Dka_hemija" title="Biofizička hemija – 塞尔维亚-克罗地亚语" lang="sh" hreflang="sh" data-title="Biofizička hemija" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="塞尔维亚-克罗地亚语" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Biophysical_chemistry" title="Biophysical chemistry – Simple English" lang="en-simple" hreflang="en-simple" data-title="Biophysical chemistry" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Biofizi%C4%8Dka_hemija" title="Biofizička hemija – 塞尔维亚语" lang="sr" hreflang="sr" data-title="Biofizička hemija" data-language-autonym="Српски / srpski" data-language-local-name="塞尔维亚语" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%89%E0%AE%AF%E0%AE%BF%E0%AE%B0%E0%AE%BF%E0%AE%AF%E0%AE%B1%E0%AF%8D%E0%AE%AA%E0%AE%BF%E0%AE%AF_%E0%AE%B5%E0%AF%87%E0%AE%A4%E0%AE%BF%E0%AE%AF%E0%AE%BF%E0%AE%AF%E0%AE%B2%E0%AF%8D" title="உயிரியற்பிய வேதியியல் – 泰米尔语" lang="ta" hreflang="ta" data-title="உயிரியற்பிய வேதியியல்" data-language-autonym="தமிழ்" data-language-local-name="泰米尔语" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%91%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D1%87%D0%BD%D0%B0_%D1%85%D1%96%D0%BC%D1%96%D1%8F" title="Біофізична хімія – 乌克兰语" lang="uk" hreflang="uk" data-title="Біофізична хімія" data-language-autonym="Українська" data-language-local-name="乌克兰语" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%B8" title="生物物理化學 – 粤语" lang="yue" hreflang="yue" data-title="生物物理化學" data-language-autonym="粵語" data-language-local-name="粤语" class="interlanguage-link-target"><span>粵語</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a 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href="/wiki/%E7%BF%BB%E8%AD%AF_(%E7%94%9F%E7%89%A9%E5%AD%B8)" title="翻译 (生物学)">翻译</a>为蛋白质的<a href="/wiki/%E5%88%86%E5%AD%90%E6%A9%9F%E5%99%A8" title="分子机器">分子机器</a>。 </figcaption></figure> <p><b>生物物理化学</b>是物理学的分支,它使用<a href="/wiki/%E7%89%A9%E7%90%86%E5%AD%A6" title="物理学">物理学</a>和<a href="/wiki/%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6" title="物理化学">物理化学</a>的概念来研究<a href="/wiki/%E7%B3%BB%E7%BB%9F%E7%94%9F%E7%89%A9%E5%AD%A6" title="系统生物学">生物系统</a>。<sup id="cite_ref-Walla2014_1-0" class="reference"><a href="#cite_note-Walla2014-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup>这门学科的研究最普遍的特征是试图根据构成系统的分子或这些系统的<a href="/wiki/%E8%B6%85%E5%88%86%E5%AD%90%E5%8C%96%E5%AD%B8" title="超分子化学">超分子</a>结构来解释生物系统中的各种现象。 &#160; </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="技术"><span id=".E6.8A.80.E6.9C.AF"></span>技术</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;action=edit&amp;section=1" title="编辑章节:技术"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>生物物理化学家采用物理化学中使用的各种技术来检测生物体系的结构。这些技术包括光谱方法,如<a href="/wiki/%E6%A0%B8%E7%A3%81%E5%85%B1%E6%8C%AF" title="核磁共振">核磁共振</a> (NMR)和<a href="/wiki/X%E5%B0%84%E7%BA%BF%E6%99%B6%E4%BD%93%E5%AD%A6" title="X射线晶体学">X射线衍射</a>。例如,2009年诺贝尔化学奖得主的工作是基于<a href="/wiki/%E6%A0%B8%E7%B3%96%E4%BD%93" title="核糖体">核糖体</a>的X射线衍射研究。<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup>生物物理化学家研究的领域之一是<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%93%E6%9E%84" title="蛋白质结构">蛋白质结构</a>和<a href="/wiki/%E7%BB%86%E8%83%9E%E8%86%9C" title="细胞膜">细胞膜</a>的功能结构。例如,研究者根据与<a href="/w/index.php?title=%E9%85%B6%E5%BA%95%E7%89%A9_(%E7%94%9F%E7%89%A9%E5%AD%A6)&amp;action=edit&amp;redlink=1" class="new" title="酶底物 (生物学)(页面不存在)">底物</a>分子的形状相匹配的蛋白质分子中的口袋形状或其由于金属离子的结合而进行的修饰来解释<a href="/wiki/%E9%85%B6" title="酶">酶的</a>作用。类似地,研究模型超分子结构,如不同组成和大小的<a href="/wiki/%E8%84%82%E8%B4%A8%E4%BD%93" title="脂质体">脂质体</a>或<a href="/wiki/%E7%A3%B7%E8%84%82" title="磷脂">磷脂</a><a href="/wiki/%E5%9B%8A%E6%B3%A1" title="囊泡">囊泡</a>,可以理解生物膜的结构和功能。 </p> <div class="mw-heading mw-heading2"><h2 id="参见"><span id=".E5.8F.82.E8.A7.81"></span>参见</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;action=edit&amp;section=2" title="编辑章节:参见"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>生物物理技术</li> <li><a href="/wiki/%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%AD%A6" title="生物物理学">生物物理学</a></li> <li><a href="/wiki/%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6" title="生物化学">生物化学</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="参考文献"><span id=".E5.8F.82.E8.80.83.E6.96.87.E7.8C.AE"></span>参考文献</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;action=edit&amp;section=3" title="编辑章节:参考文献"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist" style="list-style-type: decimal;"> <ol class="references"> <li id="cite_note-Walla2014-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-Walla2014_1-0">^</a></b></span> <span class="reference-text"><cite class="citation book">Peter Jomo Walla. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=ej__AwAAQBAJ&amp;pg=PA1">Modern Biophysical Chemistry: Detection and Analysis of Biomolecules</a>. Wiley. 8 July 2014: 1– <span class="reference-accessdate"> &#91;<span class="nowrap">2020-01-09</span>&#93;</span>. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-3-527-68354-3" title="Special:网络书源/978-3-527-68354-3"><span title="国际标准书号">ISBN</span>&#160;978-3-527-68354-3</a>. (原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20200702073643/https://books.google.com/books?id=ej__AwAAQBAJ&amp;pg=PA1">存档</a>于2020-07-02).</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;rft.au=Peter+Jomo+Walla&amp;rft.btitle=Modern+Biophysical+Chemistry%3A+Detection+and+Analysis+of+Biomolecules&amp;rft.date=2014-07-08&amp;rft.genre=book&amp;rft.isbn=978-3-527-68354-3&amp;rft.pages=1-&amp;rft.pub=Wiley&amp;rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Dej&#95;_AwAAQBAJ%26pg%3DPA1&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://nobelprize.org/nobel_prizes/chemistry/laureates/2009/press.html">The Nobel Prize in Chemistry 2009 - Press Release</a>. <span class="reference-accessdate"> &#91;<span class="nowrap">2020-01-09</span>&#93;</span>. (原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20170728212530/http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2009/press.html">存档</a>于2017-07-28).</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;rft.btitle=The+Nobel+Prize+in+Chemistry+2009+-+Press+Release&amp;rft.genre=unknown&amp;rft_id=http%3A%2F%2Fnobelprize.org%2Fnobel_prizes%2Fchemistry%2Flaureates%2F2009%2Fpress.html&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="参考书目"><span id=".E5.8F.82.E8.80.83.E4.B9.A6.E7.9B.AE"></span>参考书目</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;action=edit&amp;section=4" title="编辑章节:参考书目"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><cite class="citation book"><a href="/w/index.php?title=Charles_Cantor&amp;action=edit&amp;redlink=1" class="new" title="Charles Cantor(页面不存在)">Cantor, Charles R.</a>; <a href="/w/index.php?title=Paul_Schimmel&amp;action=edit&amp;redlink=1" class="new" title="Paul Schimmel(页面不存在)">Schimmel, Paul R.</a> Biophysical Chemistry - Part I: The Conformation of Biological Macromolecules 1st. W.H. Freeman &amp; Co Ltd. 1980. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/0716711885" title="Special:网络书源/0716711885"><span title="国际标准书号">ISBN</span>&#160;0716711885</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;rft.au=Schimmel%2C+Paul+R.&amp;rft.aufirst=Charles+R.&amp;rft.aulast=Cantor&amp;rft.btitle=Biophysical+Chemistry+-+Part+I%3A+The+Conformation+of+Biological+Macromolecules&amp;rft.date=1980&amp;rft.edition=1st&amp;rft.genre=book&amp;rft.isbn=0716711885&amp;rft.pub=W.H.+Freeman+%26+Co+Ltd&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation book"><a href="/w/index.php?title=Charles_Cantor&amp;action=edit&amp;redlink=1" class="new" title="Charles Cantor(页面不存在)">Cantor, Charles R.</a>; <a href="/w/index.php?title=Paul_Schimmel&amp;action=edit&amp;redlink=1" class="new" title="Paul Schimmel(页面不存在)">Schimmel, Paul R.</a> Biophysical Chemistry - Part II: Techniques for the Study of Biological Structure and Function 1st. W.H. Freeman &amp; Co Ltd. 1980. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/0716711907" title="Special:网络书源/0716711907"><span title="国际标准书号">ISBN</span>&#160;0716711907</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;rft.au=Schimmel%2C+Paul+R.&amp;rft.aufirst=Charles+R.&amp;rft.aulast=Cantor&amp;rft.btitle=Biophysical+Chemistry+-+Part+II%3A+Techniques+for+the+Study+of+Biological+Structure+and+Function&amp;rft.date=1980&amp;rft.edition=1st&amp;rft.genre=book&amp;rft.isbn=0716711907&amp;rft.pub=W.H.+Freeman+%26+Co+Ltd&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation book"><a href="/w/index.php?title=Charles_Cantor&amp;action=edit&amp;redlink=1" class="new" title="Charles Cantor(页面不存在)">Cantor, Charles R.</a>; <a href="/w/index.php?title=Paul_Schimmel&amp;action=edit&amp;redlink=1" class="new" title="Paul Schimmel(页面不存在)">Schimmel, Paul R.</a> Biophysical Chemistry - Part III: The Behavior of Biological Macromolecules 1st. W.H. Freeman &amp; Co Ltd. 1980. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/0716711923" title="Special:网络书源/0716711923"><span title="国际标准书号">ISBN</span>&#160;0716711923</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6&amp;rft.au=Schimmel%2C+Paul+R.&amp;rft.aufirst=Charles+R.&amp;rft.aulast=Cantor&amp;rft.btitle=Biophysical+Chemistry+-+Part+III%3A+The+Behavior+of+Biological+Macromolecules&amp;rft.date=1980&amp;rft.edition=1st&amp;rft.genre=book&amp;rft.isbn=0716711923&amp;rft.pub=W.H.+Freeman+%26+Co+Ltd&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r84265675">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output 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