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mw-first-heading"><span class="mw-page-title-main">Biofísica química</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ir para um artigo noutra língua. Disponível em 18 línguas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-18" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">18 línguas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%83%D9%8A%D9%85%D9%8A%D8%A7%D8%A1_%D9%81%D9%8A%D8%B2%D9%8A%D8%A7%D8%A6%D9%8A%D8%A9_%D8%AD%D9%8A%D9%88%D9%8A%D8%A9" title="كيمياء فيزيائية حيوية — árabe" lang="ar" hreflang="ar" data-title="كيمياء فيزيائية حيوية" data-language-autonym="العربية" data-language-local-name="árabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%91%D0%B8%D0%BE%D1%84%D0%B8%D0%B7%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0_%D1%85%D0%B8%D0%BC%D0%B8%D1%8F" title="Биофизическа химия — búlgaro" lang="bg" hreflang="bg" data-title="Биофизическа химия" data-language-autonym="Български" data-language-local-name="búlgaro" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Biofyzik%C3%A1ln%C3%AD_chemie" title="Biofyzikální chemie — checo" lang="cs" hreflang="cs" data-title="Biofyzikální chemie" data-language-autonym="Čeština" data-language-local-name="checo" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Biophysikalische_Chemie" title="Biophysikalische Chemie — alemão" lang="de" hreflang="de" data-title="Biophysikalische Chemie" data-language-autonym="Deutsch" data-language-local-name="alemão" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Biophysical_chemistry" title="Biophysical chemistry — inglês" lang="en" hreflang="en" data-title="Biophysical chemistry" data-language-autonym="English" data-language-local-name="inglês" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Biofisicoqu%C3%ADmica" title="Biofisicoquímica — espanhol" lang="es" hreflang="es" data-title="Biofisicoquímica" data-language-autonym="Español" data-language-local-name="espanhol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%B4%DB%8C%D9%85%DB%8C%E2%80%8C%D9%81%DB%8C%D8%B2%DB%8C%DA%A9_%D8%B2%DB%8C%D8%B3%D8%AA%DB%8C" title="شیمی‌فیزیک زیستی — persa" lang="fa" hreflang="fa" data-title="شیمی‌فیزیک زیستی" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Kimia_biofisika" title="Kimia biofisika — indonésio" lang="id" hreflang="id" data-title="Kimia biofisika" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonésio" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6" title="生物物理化学 — japonês" lang="ja" hreflang="ja" data-title="生物物理化学" data-language-autonym="日本語" data-language-local-name="japonês" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%83%9D%EB%AC%BC%EB%AC%BC%EB%A6%AC%ED%99%94%ED%95%99" title="생물물리화학 — coreano" lang="ko" hreflang="ko" data-title="생물물리화학" data-language-autonym="한국어" data-language-local-name="coreano" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Chimie_biofizic%C4%83" title="Chimie biofizică — romeno" lang="ro" hreflang="ro" data-title="Chimie biofizică" data-language-autonym="Română" data-language-local-name="romeno" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Biofizi%C4%8Dka_hemija" title="Biofizička hemija — servo-croata" lang="sh" hreflang="sh" data-title="Biofizička hemija" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="servo-croata" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Biophysical_chemistry" title="Biophysical chemistry — Simple English" lang="en-simple" hreflang="en-simple" data-title="Biophysical chemistry" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Biofizi%C4%8Dka_hemija" title="Biofizička hemija — sérvio" lang="sr" hreflang="sr" data-title="Biofizička hemija" data-language-autonym="Српски / srpski" data-language-local-name="sérvio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%89%E0%AE%AF%E0%AE%BF%E0%AE%B0%E0%AE%BF%E0%AE%AF%E0%AE%B1%E0%AF%8D%E0%AE%AA%E0%AE%BF%E0%AE%AF_%E0%AE%B5%E0%AF%87%E0%AE%A4%E0%AE%BF%E0%AE%AF%E0%AE%BF%E0%AE%AF%E0%AE%B2%E0%AF%8D" title="உயிரியற்பிய வேதியியல் — tâmil" lang="ta" hreflang="ta" data-title="உயிரியற்பிய வேதியியல்" data-language-autonym="தமிழ்" data-language-local-name="tâmil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%91%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D1%87%D0%BD%D0%B0_%D1%85%D1%96%D0%BC%D1%96%D1%8F" title="Біофізична хімія — ucraniano" lang="uk" hreflang="uk" data-title="Біофізична хімія" data-language-autonym="Українська" data-language-local-name="ucraniano" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6" title="生物物理化学 — chinês" lang="zh" hreflang="zh" data-title="生物物理化学" data-language-autonym="中文" data-language-local-name="chinês" class="interlanguage-link-target"><span>中文</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E7%94%9F%E7%89%A9%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%B8" title="生物物理化學 — cantonês" lang="yue" hreflang="yue" data-title="生物物理化學" data-language-autonym="粵語" data-language-local-name="cantonês" class="interlanguage-link-target"><span>粵語</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q864661#sitelinks-wikipedia" title="Editar hiperligações interlínguas" class="wbc-editpage">Editar hiperligações</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div 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id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="pt" dir="ltr"><p><b>Biofísica química</b> é um campo relativamente novo da <a href="/wiki/Qu%C3%ADmica" title="Química">química</a> que cobre um largo espectro de atividades de pesquisa envolvendo <a href="/wiki/Biologia_de_sistemas" title="Biologia de sistemas">sistemas biológicos</a>. A característica mais comum de investigação neste campo é a busca de explicação dos vários fenômenos em sistemas biológicos em termos das moléculas que compõem o sistema ou a estrutura <a href="/wiki/Qu%C3%ADmica_supramolecular" title="Química supramolecular">química supramolecular</a> destes sistemas. </p><p>Químicos biofísicos empregam várias técnicas usadas em <a href="/wiki/F%C3%ADsico-qu%C3%ADmica" title="Físico-química">físico-química</a> para provar a estrutura de sistemas biológicos. Estas técnicas incluem métodos <a href="/wiki/Espectroscopia" title="Espectroscopia">espectroscópicos</a>, como <a href="/wiki/Resson%C3%A2ncia_magn%C3%A9tica_nuclear" class="mw-redirect" title="Ressonância magnética nuclear">ressonância magnética nuclear</a> (NMR, do <a href="/wiki/L%C3%ADngua_inglesa" title="Língua inglesa">inglês</a> <i>Nuclear Magnetic Resonance</i>), <a href="/wiki/Cristalografia_de_raios_X" title="Cristalografia de raios X">difração de raios X</a>. Por exemplo, o trabalho pelo qual foram agraciados três químicos com o <a href="/wiki/Pr%C3%AAmio_Nobel" title="Prêmio Nobel">prêmio Nobel</a> em 2009 foi baseado em estudos de difração de raios X de <a href="/wiki/Ribossomo" class="mw-redirect" title="Ribossomo">ribossomos</a><sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span>[</span>1<span>]</span></a></sup>. Algumas das áreas nas quais químicos biofísicos associam-se em pesquisas são a <a href="/w/index.php?title=Estrutura_das_prote%C3%ADnas&action=edit&redlink=1" class="new" title="Estrutura das proteínas (página não existe)">estrutura das proteínas</a> e a estrutura de <a href="/wiki/Membrana_celular" title="Membrana celular">membranas celulares</a>. Por exemplo, a ação de <a href="/wiki/Enzima" title="Enzima">enzimas</a> pode ser explicada em termos da forma de um "bolsão" na molécula de proteína que adapta-se à forma da molécula <a href="/wiki/Substrato_(qu%C3%ADmica)" title="Substrato (química)">substrato</a> ou sua modificação devido à ligação de um <a href="/wiki/%C3%8Don" title="Íon">íon</a> <a href="/wiki/Metal" title="Metal">metálico</a>. Similarmente a estrutura da molécula substrato e a função de biomembranes pode ser entendida através do estudo de estruturas <a href="/wiki/Qu%C3%ADmica_supramolecular" title="Química supramolecular">supramoleculares</a> como <a href="/wiki/Lipossoma" title="Lipossoma">lipossomas</a> ou <a href="/wiki/Ves%C3%ADcula" title="Vesícula">vesículas</a> <a href="/wiki/Fosfol%C3%ADpido" title="Fosfolípido">fosfolipídicas</a> de diferentes composições e tamanhos, assim como filmes de Langmuir usados como modelos de membrana. </p><p>O mais antigo instituto de renome para a biofísica química o <a href="/w/index.php?title=Instituto_de_Biof%C3%ADsica_Qu%C3%ADmica_Max_Planck&action=edit&redlink=1" class="new" title="Instituto de Biofísica Química Max Planck (página não existe)">Instituto de Biofísica Química Max Planck</a> em <a href="/wiki/G%C3%B6ttingen" class="mw-redirect" title="Göttingen">Göttingen</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Referências"><span id="Refer.C3.AAncias"></span>Referências</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Biof%C3%ADsica_qu%C3%ADmica&veaction=edit&section=1" title="Editar secção: Referências" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Biof%C3%ADsica_qu%C3%ADmica&action=edit&section=1" title="Editar código-fonte da secção: Referências"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://nobelprize.org/nobel_prizes/chemistry/laureates/2009/press.html">The ribosome translates the DNA code into life</a> - <b>nobelprize.org</b></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Ver_também"><span id="Ver_tamb.C3.A9m"></span>Ver também</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Biof%C3%ADsica_qu%C3%ADmica&veaction=edit&section=2" title="Editar secção: Ver também" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Biof%C3%ADsica_qu%C3%ADmica&action=edit&section=2" title="Editar código-fonte da secção: Ver também"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Biof%C3%ADsica" title="Biofísica">Biofísica</a></li> <li><a href="/wiki/Bioqu%C3%ADmica" title="Bioquímica">Bioquímica</a></li> <li><a href="/wiki/T%C3%A9cnicas_biof%C3%ADsicas" class="mw-redirect" title="Técnicas biofísicas">Técnicas biofísicas</a></li></ul> <div role="navigation" class="navbox" aria-labelledby="Controle_de_autoridade" style="padding:3px"><table class="nowraplinks hlist navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th id="Controle_de_autoridade" scope="row" class="navbox-group" style="width:1%;width: 12%; 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