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The purpose of this study was to describe the anatomic localization of pancreatic inflammation, necrosis, and fibrosis in dogs presented for postmortem examination. Seventy-three pancreata from dogs presented for postmortem examination were evaluated and investigated for the presence of suppurative inflammation (SI), pancreatic necrosis (PN), and lymphocytic inflammation (LI). Sections that showed evidence of SI, PN, or LI also were evaluated for pancreatic fibrosis (F). The tendency for a preferred localization for SI, PN, and LI was evaluated by chi-square analysis. A total of 47 pancreata with histologic evidence of pancreatitis (SI, PN, or LI; F alone was not considered evidence of pancreatitis) were identified. Twenty-four (51.1%) had SI, 23 (48.9%) had PN, and 34 (72.3%) had LI. Of the 47 dogs with SI, PN, or LI, 28 (59.6%) had F. The distribution of SI, PN, and LI between the right and the left limb of the pancreas and among the 5 anatomic regions was random, based on a goodness-of-fit test. We conclude that pancreatic inflammation tends to occur in discrete areas within the pancreas rather than diffusely throughout the whole organ. These findings suggest that a single biopsy is insufficient to exclude subclinical pancreatitis and that there is no preferred site for pancreatic biopsy collection unless gross lesions are apparent.","publication_date":"2004,,","publication_name":"Journal of Veterinary Internal Medicine","grobid_abstract_attachment_id":"48173705"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Localization of Pancreatic Inflammation and Necrosis in Dogs","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [31437446]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":48173705,"attachmentType":"pdf"}"><img alt="First page of “Localization of Pancreatic Inflammation and Necrosis in Dogs”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/48173705/mini_magick20190204-25086-17wk0p6.png?1549333053" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Localization of Pancreatic Inflammation and Necrosis in Dogs</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="31437446" href="https://independent.academia.edu/DavidWilliams142"><img alt="Profile image of David Williams" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />David Williams</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2004, Journal of Veterinary Internal Medicine</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">6 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 27887248; 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Mohandas</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="27377481" href="https://innovativepublication.academia.edu/IP">IP Innovative Publication Pvt. Ltd.</a></div><p class="ds-related-work--metadata ds2-5-body-xs">IP innovative publication pvt ltd, 2020</p><p class="ds-related-work--abstract ds2-5-body-sm">Introduction: Pancreatic pseudotumor: solid non neoplastic lesions of pancreas can often mimic pancreatic cancer clinically and radiologically. Despite major evolution and development in radiology accurate diagnosis of pancreatic lesion are often difficult. The purpose of the study was to assess the diagnostic accuracy of USG in pancreatic lesion and study various solid lesions of pancreas in our tertiary care center. Materials and Methods: A descriptive study done on all resections (PPPD and Frey excision) of pancreas for a period 18 months. A total of 30 cases were included with adequate clinical and radiological features. Formalin fixed paraffin embedded sections were studied and analysed for USG findings, signs and symptoms, associated co morbidities and histological factors. Results: Females were more affected than males (1.7:1). Solid lesions presented in individuals as young as 21years to older individuals of 71yrs. The solid lesions included inflammatory lesions (such as acute and chronic pancreatitis) and neoplastic lesions. Most common clinical presentation was jaundice and vague abdominal pain accounting for 67.8 percent of study population. The histomorphological spectrum of solid lesions included 14 cases of inflammatory lesions and 16 cases of neoplastic lesion (Table 1). Among the 16 cases neoplastic lesion 5 cases had coexisting tropical pancreatitis. USG examination showed a sensitivity of 53.85%, specificity of 38.46%, positive predictive value of 46.67% and negative predictive value of 45.45% and accuracy of 46.15% for USG examination. Histomorphological features of pancreatitis were studied and most common finding was calcification (100%) present as both microscopic concretions or macroscopic calculi, followed by fatty changes (77%) and fibrosis (72%). Conclusion: Solid lesions of pancreas still pose diagnostic difficulty for clinician. USG has poor predictive value for non-neoplastic lesions. Histopathological examination remains the gold standard for diagnosis. However, emphasis for minimally invasive techniques such as FNAC must be given.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Solid lesions of pancreas a diagnostic dilemma: Utility of histopathology","attachmentId":63295306,"attachmentType":"pdf","work_url":"https://www.academia.edu/43033958/Solid_lesions_of_pancreas_a_diagnostic_dilemma_Utility_of_histopathology","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/43033958/Solid_lesions_of_pancreas_a_diagnostic_dilemma_Utility_of_histopathology"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="95842369" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/95842369/Comparison_of_clinical_findings_in_293_dogs_with_suspect_acute_pancreatitis_Different_clinical_presentation_with_left_lobe_right_lobe_or_diffuse_involvement_of_the_pancreas">Comparison of clinical findings in 293 dogs with suspect acute pancreatitis: Different clinical presentation with left lobe, right lobe or diffuse involvement of the pancreas</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="253585324" href="https://independent.academia.edu/ericlindquist9">eric lindquist</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of the South African Veterinary Association, 2020</p><p class="ds-related-work--abstract ds2-5-body-sm">Pancreatitis is a common clinical condition seen in companion animals. The correlation of the region of the pancreas affected to the presentation of clinical signs has not been previously described. A retrospective study on the clinical findings in 293 client-owned dogs diagnosed with suspect pancreatitis based on history, clinical signs, laboratory testing and abdominal ultrasonography was performed. Based on ultrasonography, dogs were divided into three groups: group 1: 41 dogs with ultrasonographic changes consistent with pancreatitis within the left lobe of the pancreas; group 2: 105 dogs with ultrasonographic changes compatible with pancreatitis within the right lobe of the pancreas; and group 3: 147 dogs with ultrasonographic evidence of diffuse pancreatitis. No significant differences regarding age, breed and sex were evident. Furthermore, statistical significance was demonstrated with the presence of pain in group 3; poor appetite in groups 2 and 3; and vomiting and diarrhoe...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Comparison of clinical findings in 293 dogs with suspect acute pancreatitis: Different clinical presentation with left lobe, right lobe or diffuse involvement of the pancreas","attachmentId":97911085,"attachmentType":"pdf","work_url":"https://www.academia.edu/95842369/Comparison_of_clinical_findings_in_293_dogs_with_suspect_acute_pancreatitis_Different_clinical_presentation_with_left_lobe_right_lobe_or_diffuse_involvement_of_the_pancreas","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/95842369/Comparison_of_clinical_findings_in_293_dogs_with_suspect_acute_pancreatitis_Different_clinical_presentation_with_left_lobe_right_lobe_or_diffuse_involvement_of_the_pancreas"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="79188940" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/79188940/Fine_needle_biopsy_of_the_pancreas_Results_of_204_routinely_performed_biopsies_in_190_patients">Fine-needle biopsy of the pancreas: Results of 204 routinely performed biopsies in 190 patients</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="139752190" href="https://independent.academia.edu/OlemartinPedersen">Ole martin Pedersen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">World Journal of Surgery, 1985</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Fine-needle biopsy of the pancreas: Results of 204 routinely performed biopsies in 190 patients","attachmentId":85988717,"attachmentType":"pdf","work_url":"https://www.academia.edu/79188940/Fine_needle_biopsy_of_the_pancreas_Results_of_204_routinely_performed_biopsies_in_190_patients","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/79188940/Fine_needle_biopsy_of_the_pancreas_Results_of_204_routinely_performed_biopsies_in_190_patients"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="115694412" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/115694412/Acute_Pancreatitis_as_the_Debut_of_a_Pancreatic_Lesion">Acute Pancreatitis as the Debut of a Pancreatic Lesion</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="297176579" href="https://independent.academia.edu/PamelaYaquich">Pamela Yaquich</a></div><p class="ds-related-work--metadata ds2-5-body-xs">MOJ Anatomy & Physiology, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Acute Pancreatitis as the Debut of a Pancreatic Lesion","attachmentId":112030078,"attachmentType":"pdf","work_url":"https://www.academia.edu/115694412/Acute_Pancreatitis_as_the_Debut_of_a_Pancreatic_Lesion","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/115694412/Acute_Pancreatitis_as_the_Debut_of_a_Pancreatic_Lesion"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="113315343" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/113315343/Severe_Acute_Pancreatitis_in_Autopsies_Associated_With_Surgeries_and_Severe_Inflammatory_Diseases">Severe Acute Pancreatitis in Autopsies Associated With Surgeries and Severe Inflammatory Diseases</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="45450847" href="https://independent.academia.edu/MasatakaKikuyama">Masataka Kikuyama</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pancreas, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Severe Acute Pancreatitis in Autopsies Associated With Surgeries and Severe Inflammatory Diseases","attachmentId":110306267,"attachmentType":"pdf","work_url":"https://www.academia.edu/113315343/Severe_Acute_Pancreatitis_in_Autopsies_Associated_With_Surgeries_and_Severe_Inflammatory_Diseases","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/113315343/Severe_Acute_Pancreatitis_in_Autopsies_Associated_With_Surgeries_and_Severe_Inflammatory_Diseases"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="38186032" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/38186032/DIAGNOSIS_OF_LOCAL_COMPLICATIONS_OF_ACUTE_PANCREATITIS_AT_THE_STAGES_OF_ITS_TREATMENT">DIAGNOSIS OF LOCAL COMPLICATIONS OF ACUTE PANCREATITIS AT THE STAGES OF ITS TREATMENT</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="59014729" href="https://independent.academia.edu/rsglobal">RS Global</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2017</p><p class="ds-related-work--abstract ds2-5-body-sm">The aim. To study the diagnostic value of individual clinical and laboratory manifestations associated with the development of intra-and peripancreatic collections according to the Atlanta 2012 Classification Review for the timely addition or modification of the tactics. Materials and methods. 72 patients were examined. In accordance with the tasks, the patients were divided into 3 groups. The first (main) group of the study consisted of 30 (41.67 %) patients who used CT for indications and the classification of acute pancreatitis was used according to the View. The comparison group consisted of 32 patients (44.44 %) who were treated in 2011 and 2013, they used the Atlanta 1992 Classification. The control group consisted of 10 patients (13.89 %) who were hospitalized for scheduled surgical intervention in a satisfactory condition. The examination was performed three times: during hospitalization (first study), 1 week (second study) and 2 weeks after hospitalization or discharge (third study). Results and discussion. The most characteristic clinical symptom is abdominal pain, which in 100 % of cases is accompanied by necrotic pancreatitis, and 70 % - oedematosis. The main laboratory symptom was lymphopenia, which occurred in 70 % of cases (78.95 % and 54.55 % for necrotic and oedematosis pancreatitis, respectively). Nausea was observed at a frequency of 70.0 %, with a significantly higher incidence (p = 0.042) in patients with necrotic pancreatitis (84.21 %) than in the subgroup with oedematosis form disease (45.45 %). Among the local complications are dominated by encapsulated forms. Lymphocyte level was determined, which helps to predict the development of local complications, their infection and the need for surgical intervention. Conclusion.The most characteristic clinical symptom is abdominal pain, which in 100 % of cases is accompanied by necrotic pancreatitis, and 70 % - oedematosis. The main laboratory symptom was lymphopenia, which occurred in 70 % of cases (78.95 % and 54.55 % for necrotic and oedematosis pancreatitis, respectively). Among the local complications are dominated by encapsulated forms. Lymphocyte level was determined, which helps to predict the development of local complications, their infection and the need for surgical intervention.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"DIAGNOSIS OF LOCAL COMPLICATIONS OF ACUTE PANCREATITIS AT THE STAGES OF ITS TREATMENT","attachmentId":58222906,"attachmentType":"pdf","work_url":"https://www.academia.edu/38186032/DIAGNOSIS_OF_LOCAL_COMPLICATIONS_OF_ACUTE_PANCREATITIS_AT_THE_STAGES_OF_ITS_TREATMENT","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/38186032/DIAGNOSIS_OF_LOCAL_COMPLICATIONS_OF_ACUTE_PANCREATITIS_AT_THE_STAGES_OF_ITS_TREATMENT"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="98210037" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/98210037/Prediction_of_Pancreatic_Necrosis_by_Dynamic_Pancreatography">Prediction of Pancreatic Necrosis by Dynamic Pancreatography</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="45776578" href="https://independent.academia.edu/DervisBandres">Dervis Bandres</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of Surgery, 1989</p><div 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href="https://independent.academia.edu/ElenaGologan">Elena Gologan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Abdominal Imaging, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Pancreas divisum pancreatitis: a case report","attachmentId":46200058,"attachmentType":"pdf","work_url":"https://www.academia.edu/25834069/Pancreas_divisum_pancreatitis_a_case_report","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/25834069/Pancreas_divisum_pancreatitis_a_case_report"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" 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