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class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">déplacer vers la barre latérale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">masquer</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Début</div> </a> </li> <li id="toc-Découverte" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Découverte"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Découverte</span> </div> </a> <ul id="toc-Découverte-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Rôle_et_fonctions" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Rôle_et_fonctions"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Rôle et fonctions</span> </div> </a> <ul id="toc-Rôle_et_fonctions-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Acide_aspartique_et_aspartame" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Acide_aspartique_et_aspartame"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Acide aspartique et aspartame</span> </div> </a> <ul id="toc-Acide_aspartique_et_aspartame-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Notes_et_références" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Notes_et_références"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Notes et références</span> </div> </a> <ul id="toc-Notes_et_références-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Voir_aussi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Voir_aussi"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Voir aussi</span> </div> </a> <button aria-controls="toc-Voir_aussi-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Afficher / masquer la sous-section Voir aussi</span> </button> <ul id="toc-Voir_aussi-sublist" class="vector-toc-list"> <li id="toc-Lien_externe" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Lien_externe"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.1</span> <span>Lien externe</span> </div> </a> <ul id="toc-Lien_externe-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sommaire" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Basculer la table des matières" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Basculer la table des matières</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Acide aspartique</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Aller à un article dans une autre langue. Disponible en 63 langues." > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-63" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">63 langues</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AD%D9%85%D8%B6_%D8%A7%D9%84%D8%A3%D8%B3%D8%A8%D8%A7%D8%B1%D8%AA%D9%8A%D9%83" title="حمض الأسبارتيك – arabe" lang="ar" hreflang="ar" data-title="حمض الأسبارتيك" data-language-autonym="العربية" data-language-local-name="arabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Asparagin_tur%C5%9Fusu" title="Asparagin turşusu – azerbaïdjanais" lang="az" hreflang="az" data-title="Asparagin turşusu" data-language-autonym="Azərbaycanca" data-language-local-name="azerbaïdjanais" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%A7%D8%B3%DB%8C%D8%AF_%D8%A2%D8%B3%D9%BE%D8%A7%D8%B1%D8%AA%DB%8C%DA%A9" title="اسید آسپارتیک – South Azerbaijani" lang="azb" hreflang="azb" data-title="اسید آسپارتیک" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-be mw-list-item"><a href="https://be.wikipedia.org/wiki/%D0%90%D1%81%D0%BF%D0%B0%D1%80%D0%B0%D0%B3%D1%96%D0%BD%D0%B0%D0%B2%D0%B0%D1%8F_%D0%BA%D1%96%D1%81%D0%BB%D0%B0%D1%82%D0%B0" title="Аспарагінавая кіслата – biélorusse" lang="be" hreflang="be" data-title="Аспарагінавая кіслата" data-language-autonym="Беларуская" data-language-local-name="biélorusse" class="interlanguage-link-target"><span>Беларуская</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%90%D1%81%D0%BF%D0%B0%D1%80%D0%B0%D0%B3%D0%B8%D0%BD%D0%BE%D0%B2%D0%B0_%D0%BA%D0%B8%D1%81%D0%B5%D0%BB%D0%B8%D0%BD%D0%B0" title="Аспарагинова киселина – bulgare" lang="bg" hreflang="bg" data-title="Аспарагинова киселина" data-language-autonym="Български" data-language-local-name="bulgare" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%85%E0%A7%8D%E0%A6%AF%E0%A6%BE%E0%A6%B8%E0%A7%8D%E0%A6%AA%E0%A6%BE%E0%A6%B0%E0%A7%8D%E0%A6%9F%E0%A6%BF%E0%A6%95_%E0%A6%85%E0%A7%8D%E0%A6%AF%E0%A6%BE%E0%A6%B8%E0%A6%BF%E0%A6%A1" title="অ্যাস্পার্টিক অ্যাসিড – bengali" lang="bn" hreflang="bn" data-title="অ্যাস্পার্টিক অ্যাসিড" data-language-autonym="বাংলা" data-language-local-name="bengali" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Asparaginska_kiselina" title="Asparaginska kiselina – bosniaque" lang="bs" hreflang="bs" data-title="Asparaginska kiselina" data-language-autonym="Bosanski" data-language-local-name="bosniaque" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/%C3%80cid_asp%C3%A0rtic" title="Àcid aspàrtic – catalan" lang="ca" hreflang="ca" data-title="Àcid aspàrtic" data-language-autonym="Català" data-language-local-name="catalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Kyselina_asparagov%C3%A1" title="Kyselina asparagová – tchèque" lang="cs" hreflang="cs" data-title="Kyselina asparagová" data-language-autonym="Čeština" data-language-local-name="tchèque" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Asparagins%C3%A4ure" title="Asparaginsäure – allemand" lang="de" hreflang="de" data-title="Asparaginsäure" data-language-autonym="Deutsch" data-language-local-name="allemand" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%91%CF%83%CF%80%CE%B1%CF%81%CE%B1%CE%B3%CE%B9%CE%BD%CE%B9%CE%BA%CF%8C_%CE%BF%CE%BE%CF%8D" title="Ασπαραγινικό οξύ – grec" lang="el" hreflang="el" data-title="Ασπαραγινικό οξύ" data-language-autonym="Ελληνικά" data-language-local-name="grec" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Aspartic_acid" title="Aspartic acid – anglais" lang="en" hreflang="en" data-title="Aspartic acid" data-language-autonym="English" data-language-local-name="anglais" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Aspartata_acido" title="Aspartata acido – espéranto" lang="eo" hreflang="eo" data-title="Aspartata acido" data-language-autonym="Esperanto" data-language-local-name="espéranto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/%C3%81cido_asp%C3%A1rtico" title="Ácido aspártico – espagnol" lang="es" hreflang="es" data-title="Ácido aspártico" data-language-autonym="Español" data-language-local-name="espagnol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Asparagiinhape" title="Asparagiinhape – estonien" lang="et" hreflang="et" data-title="Asparagiinhape" data-language-autonym="Eesti" data-language-local-name="estonien" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Azido_aspartiko" title="Azido aspartiko – basque" lang="eu" hreflang="eu" data-title="Azido aspartiko" data-language-autonym="Euskara" data-language-local-name="basque" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%D8%B3%DB%8C%D8%AF_%D8%A2%D8%B3%D9%BE%D8%A7%D8%B1%D8%AA%DB%8C%DA%A9" title="اسید آسپارتیک – persan" lang="fa" hreflang="fa" data-title="اسید آسپارتیک" data-language-autonym="فارسی" data-language-local-name="persan" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Asparagiinihappo" title="Asparagiinihappo – finnois" lang="fi" hreflang="fi" data-title="Asparagiinihappo" data-language-autonym="Suomi" data-language-local-name="finnois" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Aig%C3%A9ad_aspartach" title="Aigéad aspartach – irlandais" lang="ga" hreflang="ga" data-title="Aigéad aspartach" data-language-autonym="Gaeilge" data-language-local-name="irlandais" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/%C3%81cido_asp%C3%A1rtico" title="Ácido aspártico – galicien" lang="gl" hreflang="gl" data-title="Ácido aspártico" data-language-autonym="Galego" data-language-local-name="galicien" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%97%D7%95%D7%9E%D7%A6%D7%94_%D7%90%D7%A1%D7%A4%D7%A8%D7%98%D7%99%D7%AA" title="חומצה אספרטית – hébreu" lang="he" hreflang="he" data-title="חומצה אספרטית" data-language-autonym="עברית" data-language-local-name="hébreu" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%8F%E0%A4%B8%E0%A5%8D%E0%A4%AA%E0%A4%BE%E0%A4%B0%E0%A5%8D%E0%A4%9F%E0%A4%BF%E0%A4%95_%E0%A4%85%E0%A4%AE%E0%A5%8D%E0%A4%B2" title="एस्पार्टिक अम्ल – hindi" lang="hi" hreflang="hi" data-title="एस्पार्टिक अम्ल" data-language-autonym="हिन्दी" data-language-local-name="hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Asparaginska_kiselina" title="Asparaginska kiselina – croate" lang="hr" hreflang="hr" data-title="Asparaginska kiselina" data-language-autonym="Hrvatski" data-language-local-name="croate" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Aszparaginsav" title="Aszparaginsav – hongrois" lang="hu" hreflang="hu" data-title="Aszparaginsav" data-language-autonym="Magyar" data-language-local-name="hongrois" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%B1%D5%BD%D5%BA%D5%A1%D6%80%D5%A1%D5%A3%D5%AB%D5%B6%D5%A1%D5%A9%D5%A9%D5%B8%D6%82" title="Ասպարագինաթթու – arménien" lang="hy" hreflang="hy" data-title="Ասպարագինաթթու" data-language-autonym="Հայերեն" data-language-local-name="arménien" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Asam_aspartat" title="Asam aspartat – indonésien" lang="id" hreflang="id" data-title="Asam aspartat" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonésien" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Acido_aspartico" title="Acido aspartico – italien" lang="it" hreflang="it" data-title="Acido aspartico" data-language-autonym="Italiano" data-language-local-name="italien" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A2%E3%82%B9%E3%83%91%E3%83%A9%E3%82%AE%E3%83%B3%E9%85%B8" title="アスパラギン酸 – japonais" lang="ja" hreflang="ja" data-title="アスパラギン酸" data-language-autonym="日本語" data-language-local-name="japonais" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%90%D1%81%D0%BF%D0%B0%D1%80%D0%B0%D0%B3%D0%B8%D0%BD_%D2%9B%D1%8B%D1%88%D2%9B%D1%8B%D0%BB%D1%8B" title="Аспарагин қышқылы – kazakh" lang="kk" hreflang="kk" data-title="Аспарагин қышқылы" data-language-autonym="Қазақша" data-language-local-name="kazakh" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%95%84%EC%8A%A4%ED%8C%8C%EB%A5%B4%ED%8A%B8%EC%82%B0" title="아스파르트산 – coréen" lang="ko" hreflang="ko" data-title="아스파르트산" data-language-autonym="한국어" data-language-local-name="coréen" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Tir%C5%9Feya_aspart%C3%AE" title="Tirşeya aspartî – kurde" lang="ku" hreflang="ku" data-title="Tirşeya aspartî" data-language-autonym="Kurdî" data-language-local-name="kurde" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-ky mw-list-item"><a href="https://ky.wikipedia.org/wiki/%D0%90%D1%81%D0%BF%D0%B0%D1%80%D0%B0%D0%B3%D0%B8%D0%BD_%D0%BA%D0%B8%D1%81%D0%BB%D0%BE%D1%82%D0%B0%D1%81%D1%8B" title="Аспарагин кислотасы – kirghize" lang="ky" hreflang="ky" data-title="Аспарагин кислотасы" data-language-autonym="Кыргызча" data-language-local-name="kirghize" class="interlanguage-link-target"><span>Кыргызча</span></a></li><li class="interlanguage-link interwiki-lb mw-list-item"><a href="https://lb.wikipedia.org/wiki/Aspartat" title="Aspartat – luxembourgeois" lang="lb" hreflang="lb" data-title="Aspartat" data-language-autonym="Lëtzebuergesch" data-language-local-name="luxembourgeois" class="interlanguage-link-target"><span>Lëtzebuergesch</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Asparto_r%C5%ABg%C5%A1tis" title="Asparto rūgštis – lituanien" lang="lt" hreflang="lt" data-title="Asparto rūgštis" data-language-autonym="Lietuvių" data-language-local-name="lituanien" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Asparag%C4%ABnsk%C4%81be" title="Asparagīnskābe – letton" lang="lv" hreflang="lv" data-title="Asparagīnskābe" data-language-autonym="Latviešu" data-language-local-name="letton" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%90%D1%81%D0%BF%D0%B0%D1%80%D0%B0%D0%B3%D0%B8%D0%BD%D1%81%D0%BA%D0%B0_%D0%BA%D0%B8%D1%81%D0%B5%D0%BB%D0%B8%D0%BD%D0%B0" title="Аспарагинска киселина – macédonien" lang="mk" hreflang="mk" data-title="Аспарагинска киселина" data-language-autonym="Македонски" data-language-local-name="macédonien" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Asid_aspartik" title="Asid aspartik – malais" lang="ms" hreflang="ms" data-title="Asid aspartik" data-language-autonym="Bahasa Melayu" data-language-local-name="malais" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Asparaginezuur" title="Asparaginezuur – néerlandais" lang="nl" hreflang="nl" data-title="Asparaginezuur" data-language-autonym="Nederlands" data-language-local-name="néerlandais" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Asparaginsyre" title="Asparaginsyre – norvégien nynorsk" lang="nn" hreflang="nn" data-title="Asparaginsyre" data-language-autonym="Norsk nynorsk" data-language-local-name="norvégien nynorsk" class="interlanguage-link-target"><span>Norsk nynorsk</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Asparaginsyre" title="Asparaginsyre – norvégien bokmål" lang="nb" hreflang="nb" data-title="Asparaginsyre" data-language-autonym="Norsk bokmål" data-language-local-name="norvégien bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Acid_aspartic" title="Acid aspartic – occitan" lang="oc" hreflang="oc" data-title="Acid aspartic" data-language-autonym="Occitan" data-language-local-name="occitan" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Kwas_asparaginowy" title="Kwas asparaginowy – polonais" lang="pl" hreflang="pl" data-title="Kwas asparaginowy" data-language-autonym="Polski" data-language-local-name="polonais" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/%C3%81cido_asp%C3%A1rtico" title="Ácido aspártico – portugais" lang="pt" hreflang="pt" data-title="Ácido aspártico" data-language-autonym="Português" data-language-local-name="portugais" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Acid_aspartic" title="Acid aspartic – roumain" lang="ro" hreflang="ro" data-title="Acid aspartic" data-language-autonym="Română" data-language-local-name="roumain" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%90%D1%81%D0%BF%D0%B0%D1%80%D0%B0%D0%B3%D0%B8%D0%BD%D0%BE%D0%B2%D0%B0%D1%8F_%D0%BA%D0%B8%D1%81%D0%BB%D0%BE%D1%82%D0%B0" title="Аспарагиновая кислота – russe" lang="ru" hreflang="ru" data-title="Аспарагиновая кислота" data-language-autonym="Русский" data-language-local-name="russe" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sco mw-list-item"><a href="https://sco.wikipedia.org/wiki/Aspartic_acid" title="Aspartic acid – écossais" lang="sco" hreflang="sco" data-title="Aspartic acid" data-language-autonym="Scots" data-language-local-name="écossais" class="interlanguage-link-target"><span>Scots</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Asparaginska_kiselina" title="Asparaginska kiselina – serbo-croate" lang="sh" hreflang="sh" data-title="Asparaginska kiselina" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbo-croate" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Aspartic_acid" title="Aspartic acid – Simple English" lang="en-simple" hreflang="en-simple" data-title="Aspartic acid" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Kyselina_aspar%C3%A1gov%C3%A1" title="Kyselina asparágová – slovaque" lang="sk" hreflang="sk" data-title="Kyselina asparágová" data-language-autonym="Slovenčina" data-language-local-name="slovaque" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Asparaginska_kislina" title="Asparaginska kislina – slovène" lang="sl" hreflang="sl" data-title="Asparaginska kislina" data-language-autonym="Slovenščina" data-language-local-name="slovène" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Asparaginska_kiselina" title="Asparaginska kiselina – serbe" lang="sr" hreflang="sr" data-title="Asparaginska kiselina" data-language-autonym="Српски / srpski" data-language-local-name="serbe" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-su mw-list-item"><a href="https://su.wikipedia.org/wiki/Asam_aspartat" title="Asam aspartat – soundanais" lang="su" hreflang="su" data-title="Asam aspartat" data-language-autonym="Sunda" data-language-local-name="soundanais" class="interlanguage-link-target"><span>Sunda</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Asparaginsyra" title="Asparaginsyra – suédois" lang="sv" hreflang="sv" data-title="Asparaginsyra" data-language-autonym="Svenska" data-language-local-name="suédois" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%85%E0%AE%B8%E0%AF%8D%E0%AE%AA%E0%AE%BE%E0%AE%B0%E0%AF%8D%E0%AE%9F%E0%AE%BF%E0%AE%95%E0%AF%8D_%E0%AE%85%E0%AE%AE%E0%AE%BF%E0%AE%B2%E0%AE%AE%E0%AF%8D" title="அஸ்பார்டிக் அமிலம் – tamoul" lang="ta" hreflang="ta" data-title="அஸ்பார்டிக் அமிலம்" data-language-autonym="தமிழ்" data-language-local-name="tamoul" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%81%E0%B8%A3%E0%B8%94%E0%B9%81%E0%B8%AD%E0%B8%AA%E0%B8%9B%E0%B8%B2%E0%B8%A3%E0%B9%8C%E0%B8%95%E0%B8%B4%E0%B8%81" title="กรดแอสปาร์ติก – thaï" lang="th" hreflang="th" data-title="กรดแอสปาร์ติก" data-language-autonym="ไทย" data-language-local-name="thaï" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Aspartik_asit" title="Aspartik asit – turc" lang="tr" hreflang="tr" data-title="Aspartik asit" data-language-autonym="Türkçe" data-language-local-name="turc" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%90%D1%81%D0%BF%D0%B0%D1%80%D0%B0%D0%B3%D1%96%D0%BD%D0%BE%D0%B2%D0%B0_%D0%BA%D0%B8%D1%81%D0%BB%D0%BE%D1%82%D0%B0" title="Аспарагінова кислота – ukrainien" lang="uk" hreflang="uk" data-title="Аспарагінова кислота" data-language-autonym="Українська" data-language-local-name="ukrainien" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Asparagin_kislota" title="Asparagin kislota – ouzbek" lang="uz" hreflang="uz" data-title="Asparagin kislota" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="ouzbek" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Acid_aspartic" title="Acid aspartic – vietnamien" lang="vi" hreflang="vi" data-title="Acid aspartic" data-language-autonym="Tiếng Việt" data-language-local-name="vietnamien" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E5%A4%A9%E5%86%AC%E6%B0%A8%E9%85%B8" title="天冬氨酸 – wu" lang="wuu" hreflang="wuu" data-title="天冬氨酸" data-language-autonym="吴语" data-language-local-name="wu" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%A4%A9%E9%97%A8%E5%86%AC%E6%B0%A8%E9%85%B8" title="天门冬氨酸 – chinois" lang="zh" hreflang="zh" data-title="天门冬氨酸" data-language-autonym="中文" data-language-local-name="chinois" class="interlanguage-link-target"><span>中文</span></a></li><li class="interlanguage-link interwiki-zh-min-nan mw-list-item"><a href="https://zh-min-nan.wikipedia.org/wiki/Asparagin-sng" title="Asparagin-sng – minnan" lang="nan" hreflang="nan" data-title="Asparagin-sng" data-language-autonym="閩南語 / Bân-lâm-gú" data-language-local-name="minnan" class="interlanguage-link-target"><span>閩南語 / Bân-lâm-gú</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E5%A4%A9%E9%96%80%E5%86%AC%E6%B0%A8%E9%85%B8" title="天門冬氨酸 – cantonais" lang="yue" hreflang="yue" data-title="天門冬氨酸" data-language-autonym="粵語" data-language-local-name="cantonais" class="interlanguage-link-target"><span>粵語</span></a></li> </ul> <div 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class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="fr" dir="ltr"><div class="bandeau-container metadata homonymie hatnote"><div class="bandeau-cell bandeau-icone" style="display:table-cell;padding-right:0.5em"><span class="noviewer" typeof="mw:File"><a href="/wiki/Aide:Homonymie" title="Aide:Homonymie"><img alt="Page d’aide sur l’homonymie" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a9/Logo_disambig.svg/20px-Logo_disambig.svg.png" decoding="async" width="20" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a9/Logo_disambig.svg/30px-Logo_disambig.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a9/Logo_disambig.svg/40px-Logo_disambig.svg.png 2x" data-file-width="512" data-file-height="375" /></a></span></div><div class="bandeau-cell" style="display:table-cell;padding-right:0.5em"> <p>Pour les articles homonymes, voir <a href="/w/index.php?title=ASPGAU&action=edit&redlink=1" class="new" title="ASPGAU (page inexistante)">ASPGAU</a> et <a href="/wiki/GAC" class="mw-disambig" title="GAC">GAC</a>. </p> </div></div> <p class="mw-empty-elt"> </p> <table class="infobox_v2 infobox infobox--frwiki noarchive"> <tbody><tr> <td colspan="2" class="entete defaut" style="background-color:#FFDEAD;color:black;">Acide aspartique </td></tr> <tr><td colspan="2" style="display:none;"> </td></tr> <tr> <td colspan="2" style="text-align:center;"><span typeof="mw:File"><a href="/wiki/Fichier:L-Asparagins%C3%A4ure_-_L-Aspartic_acid.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/ce/L-Asparagins%C3%A4ure_-_L-Aspartic_acid.svg/150px-L-Asparagins%C3%A4ure_-_L-Aspartic_acid.svg.png" decoding="async" width="150" height="89" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/ce/L-Asparagins%C3%A4ure_-_L-Aspartic_acid.svg/225px-L-Asparagins%C3%A4ure_-_L-Aspartic_acid.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/ce/L-Asparagins%C3%A4ure_-_L-Aspartic_acid.svg/300px-L-Asparagins%C3%A4ure_-_L-Aspartic_acid.svg.png 2x" data-file-width="205" data-file-height="121" /></a></span><br /><b>Acide L ou <i>S</i>(+)-aspartique</b><br /><br /><span typeof="mw:File"><a href="/wiki/Fichier:D-Aspartic_acid.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/D-Aspartic_acid.svg/150px-D-Aspartic_acid.svg.png" decoding="async" width="150" height="96" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/D-Aspartic_acid.svg/225px-D-Aspartic_acid.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/08/D-Aspartic_acid.svg/300px-D-Aspartic_acid.svg.png 2x" data-file-width="196" data-file-height="125" /></a></span><br /><b>Acide D ou <i>R</i>(-)-aspartique</b></td> </tr><tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#FFDEAD; color:#000000">Identification</th></tr> <tr> <th scope="row"><a href="/wiki/Nomenclature_de_l%27UICPA" title="Nomenclature de l'UICPA">Nom UICPA</a> </th> <td><small>acide (2<i>S</i>)-2-aminobutanedioïque</small> </td> </tr> <tr> <th scope="row"><a href="/wiki/Synonymie" title="Synonymie">Synonymes</a> </th> <td> <p><a href="/wiki/D_(lettre)" title="D (lettre)">D</a>, Asp<br /> acide 2-aminosuccinique </p> </td> </tr> <tr> <th scope="row"><a href="/wiki/Num%C3%A9ro_CAS" title="Numéro CAS">N<sup>o</sup> CAS</a> </th> <td><span class="reflink plainlinksneverexpand"><span class="noarchive"><a class="external text" href="//tools.wmflabs.org/magnustools/cas.php?cas=617-45-8&language=fr&title=Acide_aspartique">617-45-8</a></span></span> (racémique)<br /><span class="reflink plainlinksneverexpand"><span class="noarchive"><a class="external text" href="//tools.wmflabs.org/magnustools/cas.php?cas=56-84-8&language=fr&title=Acide_aspartique">56-84-8</a></span></span> (L) ou <i>S</i>(+)<br /><span class="reflink plainlinksneverexpand"><span class="noarchive"><a class="external text" href="//tools.wmflabs.org/magnustools/cas.php?cas=1783-96-6&language=fr&title=Acide_aspartique">1783-96-6</a></span></span> (D) ou <i>R</i>(–) </td> </tr> <tr> <th scope="row"> N<sup>o</sup> <a href="/wiki/Agence_europ%C3%A9enne_des_produits_chimiques" title="Agence européenne des produits chimiques">ECHA</a> </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.000.265">100.000.265</a></span></span></td> </tr> <tr> <th scope="row"><a href="/wiki/Num%C3%A9ro_CE" title="Numéro CE">N<sup>o</sup> CE</a> </th> <td>200-291-6 (L)<br />217-234-6 (D) </td> </tr> <tr> <th scope="row"><a href="/wiki/PubChem" title="PubChem">PubChem</a> </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/424">424</a></span></span> </td> </tr> <tr> <th scope="row">ChEBI </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/chebi/searchId.do?chebiId=22660">22660</a></span></span> </td> </tr> <tr> <th scope="row"><a href="/wiki/GRAS" class="mw-redirect" title="GRAS"><span title="Flavor and Extract Manufacturers Association">FEMA</span></a> </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="http://www.fao.org/ag/agn/jecfa-flav/results.html?flavName=&groupName=-1&searchBy=fema&jecfa=&fema=3656&cas1=&cas2=&cas3="><span title="laevo-aspartic acid">3656</span></a></span></span> </td> </tr> <tr> <th scope="row"><a href="/wiki/Simplified_Molecular_Input_Line_Entry_System" title="Simplified Molecular Input Line Entry System">SMILES</a> </th> <td><div class="NavFrame" title="[Afficher]/[Masquer]" style="border: none; padding: 0;"><div class="NavContent" style="display: none; text-align: left;">O=C(O)CC(N)C(=O)O <br /><span class="reflink plainlinksneverexpand"><a rel="nofollow" class="external text" href="http://pubchem.ncbi.nlm.nih.gov/search/?smarts=O%3DC%28O%29CC%28N%29C%28%3DO%29O">PubChem</a></span>, <span class="reflink plainlinksneverexpand"><a rel="nofollow" class="external text" href="http://chemapps.stolaf.edu/jmol/jmol.php?title=Acide+aspartique&model=O%3DC%28O%29CC%28N%29C%28%3DO%29O">vue 3D</a></span></div></div> </td> </tr> <tr> <th scope="row"><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a> </th> <td><div class="NavFrame" title="[Afficher]/[Masquer]" style="border: none; padding: 0;"><div class="NavContent" style="display: none; text-align: left;"><b>InChI :</b> <span class="reflink plainlinksneverexpand"><a rel="nofollow" class="external text" href="http://chemapps.stolaf.edu/jmol/jmol.php?title=Acide+aspartique&model=InChI%3D1%2FC4H7NO4%2Fc5-2%284%288%299%291-3%286%297%2Fh2H%2C1%2C5H2%2C%28H%2C6%2C7%29%28H%2C8%2C9%29">vue 3D</a></span> <br />InChI=1/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9) <br /><b>InChIKey :</b> <br />CKLJMWTZIZZHCS-UHFFFAOYAE <br /><b>Std. InChI :</b> <span class="reflink plainlinksneverexpand"><a rel="nofollow" class="external text" href="http://chemapps.stolaf.edu/jmol/jmol.php?title=Acide+aspartique&model=InChI%3D1S%2FC4H7NO4%2Fc5-2%284%288%299%291-3%286%297%2Fh2H%2C1%2C5H2%2C%28H%2C6%2C7%29%28H%2C8%2C9%29">vue 3D</a></span> <br />InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9) <br /><b>Std. InChIKey :</b> <br />CKLJMWTZIZZHCS-UHFFFAOYSA-N</div></div> </td> </tr> <tr> <th scope="row">Apparence </th> <td>cristaux incolores<sup id="cite_ref-ICSC_1-0" class="reference"><a href="#cite_note-ICSC-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#FFDEAD; color:#000000">Propriétés chimiques</th></tr> <tr> <th scope="row"><a href="/wiki/Formule_chimique" title="Formule chimique">Formule</a> </th> <td><a href="/wiki/Carbone" title="Carbone">C</a><sub>4</sub><a href="/wiki/Hydrog%C3%A8ne" title="Hydrogène">H</a><sub>7</sub><a href="/wiki/Azote" title="Azote">N</a><a href="/wiki/Oxyg%C3%A8ne" title="Oxygène">O</a><sub>4</sub>  <span class="page_h"><a href="/wiki/C4H7NO4" class="mw-disambig" title="C4H7NO4"><small>[Isomères]</small></a></span><br /> </td> </tr> <tr> <th scope="row"><a href="/wiki/Masse_molaire" title="Masse molaire">Masse molaire</a><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup> </th> <td>133,102 7 ± 0,005 1 <a href="/wiki/Gramme" title="Gramme">g</a>/<a href="/wiki/Mole_(unit%C3%A9)" title="Mole (unité)">mol</a> <br /><small>C 36,09 %,  H 5,3 %,  N 10,52 %,  O 48,08 %,  </small> </td> </tr> <tr> <th scope="row"><a href="/wiki/Constante_d%27acidit%C3%A9" title="Constante d'acidité">p<i>K</i><sub>a</sub></a> </th> <td>2,0<br />10,0 <br />3,9 </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#f7efa8; color:#000000">Propriétés physiques</th></tr> <tr> <th scope="row"><a href="/wiki/Point_de_fusion" title="Point de fusion"><abbr class="abbr" title="Température">T°</abbr> fusion</a> </th> <td><span title="518 °F ou 543,2 K">270 </span><abbr class="abbr" title="degré Celsius">°C</abbr><sup id="cite_ref-ICSC_1-1" class="reference"><a href="#cite_note-ICSC-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th scope="row"><a href="/wiki/Point_d%27%C3%A9bullition" title="Point d'ébullition"><abbr class="abbr" title="Température">T°</abbr> ébullition</a> </th> <td>Se décompose au-dessous du point d'ébullition à <span title="615,2 °F ou 597,2 K">324 </span><abbr class="abbr" title="degré Celsius">°C</abbr><sup id="cite_ref-ICSC_1-2" class="reference"><a href="#cite_note-ICSC-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th scope="row"><a href="/wiki/Solubilit%C3%A9" title="Solubilité">Solubilité</a> </th> <td>dans l'eau : <span class="nowrap"><span title="">4,5</span> <span title="Gramme">g</span>·<span title="Litre">l</span><sup>-1</sup></span><sup id="cite_ref-ICSC_1-3" class="reference"><a href="#cite_note-ICSC-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th scope="row"><a href="/wiki/Masse_volumique" title="Masse volumique">Masse volumique</a> </th> <td><span class="nowrap"><span title="1 700 kg⋅m⁻³ ou 59,71 °Baumé">1,7</span> <span title="Gramme">g</span>·<span title="centimètre">cm</span><sup>-3</sup></span><sup id="cite_ref-ICSC_1-4" class="reference"><a href="#cite_note-ICSC-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#FFDEAD; color:#000000">Propriétés biochimiques</th></tr> <tr> <th scope="row"><a href="/wiki/Code_g%C3%A9n%C3%A9tique#Codons" title="Code génétique">Codons</a> </th> <td>GAU, GAC </td> </tr> <tr> <th scope="row"><a href="/wiki/Point_iso%C3%A9lectrique" title="Point isoélectrique">pH isoélectrique</a> </th> <td>2,77<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite_crochet">[</span>3<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th scope="row"><a href="/wiki/Acide_amin%C3%A9_essentiel" title="Acide aminé essentiel">Acide aminé essentiel</a> </th> <td>Non </td></tr><tr><th style="padding: 2px 0px;">Occurrence chez les <a href="/wiki/Vert%C3%A9br%C3%A9s" title="Vertébrés">vertébrés</a></th><td>5,9 %<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite_crochet">[</span>4<span class="cite_crochet">]</span></a></sup></td></tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#FFDEAD; color:#000000">Cristallographie</th></tr> <tr> <th scope="row"><a href="/wiki/Classe_cristalline" title="Classe cristalline">Classe cristalline</a> ou <a href="/wiki/Groupe_d%27espace" title="Groupe d'espace">groupe d’espace</a> </th> <td><i>P</i>2<sub>1</sub> (L)<sup id="cite_ref-reciprocalnet_5-0" class="reference"><a href="#cite_note-reciprocalnet-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th scope="row"><a href="/wiki/Param%C3%A8tre_cristallin" title="Paramètre cristallin">Paramètres de maille</a> </th> <td><i>a</i> = <span class="nowrap"><span title="0,761 7 nm">7,617</span> <span title="Ångström">Å</span></span> <br /> <p><i>b</i> = <span class="nowrap"><span title="0,698 2 nm">6,982</span> <span title="Ångström">Å</span></span> <br /> <i>c</i> = <span class="nowrap"><span title="0,514 2 nm">5,142</span> <span title="Ångström">Å</span></span> <br /> α = <span class="nowrap"><span title="π/2 ou 1,570 8 radians">90,00</span> <span title="Degré">°</span></span> <br /> β = <span class="nowrap"><span title="1,742 5 radians">99,84</span> <span title="Degré">°</span></span> <br /> γ = <span class="nowrap"><span title="π/2 ou 1,570 8 radians">90,00</span> <span title="Degré">°</span></span> <br /> Z = 4 (L)<sup id="cite_ref-reciprocalnet_5-1" class="reference"><a href="#cite_note-reciprocalnet-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup> </p> </td> </tr> <tr> <th scope="row">Volume </th> <td><span class="nowrap"><span title="">269,44</span> <span title="Ångström">Å</span><sup>3</sup></span> (L)<sup id="cite_ref-reciprocalnet_5-2" class="reference"><a href="#cite_note-reciprocalnet-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#FFDEAD; color:#000000">Propriétés optiques</th></tr> <tr> <th scope="row"><a href="/wiki/Pouvoir_rotatoire" title="Pouvoir rotatoire">Pouvoir rotatoire</a> </th> <td>+<span class="nowrap"><span title="π/36 ou 0,087 3 radians">5,0</span> <span title="Degré">°</span></span> .dm<sup>-1</sup>.g<sup>-1</sup>.cm³ </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#ffb4b4; color:#000000">Précautions</th></tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#eeeeee; color:#000000"><a href="/wiki/Syst%C3%A8me_d%27information_sur_les_mati%C3%A8res_dangereuses_utilis%C3%A9es_au_travail" title="Système d'information sur les matières dangereuses utilisées au travail">SIMDUT</a><sup id="cite_ref-Reptox_6-0" class="reference"><a href="#cite_note-Reptox-6"><span class="cite_crochet">[</span>6<span class="cite_crochet">]</span></a></sup></th></tr> <tr> <td colspan="2" style="text-align:center;"><br />Produit non contrôlé<div class="NavFrame" title="[+]/[–]" style="border:none; padding: 0;"><div class="NavContent" style="display:none; text-align:left;">Ce produit n'est pas contrôlé selon les critères de classification du SIMDUT.</div></div></td> </tr><tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#ffb4b4; color:#000000"><a href="/wiki/%C3%89cotoxicologie" title="Écotoxicologie">Écotoxicologie</a></th></tr> <tr> <th scope="row"><a href="/wiki/LogP" title="LogP">LogP</a> </th> <td>-3,89<sup id="cite_ref-ICSC_1-5" class="reference"><a href="#cite_note-ICSC-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> </td> </tr> <tr> <td colspan="2"><hr style="height:2px; background-color:#FFDEAD;" /></td></tr> <tr> <td colspan="2" style="text-align:center;">Unités du <a href="/wiki/Syst%C3%A8me_international_d%27unit%C3%A9s" title="Système international d'unités">SI</a> et <a href="/wiki/Conditions_normales_de_temp%C3%A9rature_et_de_pression" title="Conditions normales de température et de pression"><abbr title="conditions normales de température et de pression">CNTP</abbr></a>, sauf indication contraire.</td> </tr><tr> <td class="navigation-only" colspan="2" style="border-top: 2px #FFDEAD solid; font-size: 80%; background:inherit; text-align: right;"><span class="plainlinks" style="float:left;"><a class="external text" href="https://fr.wikipedia.org/w/index.php?title=Acide_aspartique&action=edit&section=0"><span class="infodoc">modifier</span></a></span> <span typeof="mw:File"><a href="/wiki/Mod%C3%A8le:Infobox_Chimie" title="Consultez la documentation du modèle"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/12px-Info_Simple.svg.png" decoding="async" width="12" height="12" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/18px-Info_Simple.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/24px-Info_Simple.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></td> </tr> </tbody></table> <p>L’<b>acide aspartique</b> (abréviations <a href="/wiki/Union_internationale_de_chimie_pure_et_appliqu%C3%A9e" title="Union internationale de chimie pure et appliquée">IUPAC</a>-<a href="/wiki/Union_internationale_de_biochimie_et_de_biologie_mol%C3%A9culaire" title="Union internationale de biochimie et de biologie moléculaire">IUBMB</a> : <b>Asp</b> et <b>D</b>), est un <a href="/wiki/Acide_amin%C3%A9" title="Acide aminé">acide <span class="nowrap">α-aminé</span></a> dont l'<a href="/wiki/%C3%89nantiom%C3%A9rie" title="Énantiomérie">énantiomère</a> <small>L</small> est l'un des <a href="/wiki/Acide_amin%C3%A9_prot%C3%A9inog%C3%A8ne" title="Acide aminé protéinogène">22 acides aminés protéinogènes</a>, <a href="/wiki/Code_g%C3%A9n%C3%A9tique" title="Code génétique">encodé</a> sur les <a href="/wiki/Acide_ribonucl%C3%A9ique_messager" title="Acide ribonucléique messager">ARN messagers</a> par les <a href="/wiki/Codon" title="Codon">codons</a> GAU et GAC. Il est caractérisé par la présence d'un <a href="/wiki/Groupe_fonctionnel" title="Groupe fonctionnel">groupe</a> <a href="/wiki/Carboxyle" title="Carboxyle">carboxyle</a> –COOH à l'extrémité de sa <a href="/wiki/Cha%C3%AEne_lat%C3%A9rale" title="Chaîne latérale">chaîne latérale</a>, lui conférant un <a href="/wiki/Point_iso%C3%A9lectrique" title="Point isoélectrique">point isoélectrique</a> de 2,77, ce qui en fait le <a href="/wiki/R%C3%A9sidu_(biochimie)" title="Résidu (biochimie)">résidu</a> le plus <a href="/wiki/Acide" title="Acide">acide</a> dans les <a href="/wiki/Prot%C3%A9ine" title="Protéine">protéines</a>. Son <a href="/wiki/Anion" title="Anion">anion</a> et <a href="/wiki/Base_conjugu%C3%A9e" title="Base conjuguée">base conjuguée</a> est l'aspartate et son <a href="/wiki/Rayon_de_van_der_Waals" title="Rayon de van der Waals">rayon de van der Waals</a> vaut <span class="nowrap"><span title="">291</span> <span title=""><a href="/wiki/Picom%C3%A8tre" title="Picomètre">pm</a></span></span>. </p><p>Il s'agit d'un <a href="/wiki/Acide_dicarboxylique" title="Acide dicarboxylique">acide dicarboxylique</a>, et donc d'une molécule <a href="/wiki/Polarit%C3%A9_(chimie)" title="Polarité (chimie)">polaire</a>. Chez les mammifères, il est <a href="/wiki/Acide_amin%C3%A9_essentiel" title="Acide aminé essentiel">non essentiel</a>. C'est un <a href="/wiki/M%C3%A9tabolite" title="Métabolite">métabolite</a> du <a href="/wiki/Cycle_de_l%27ur%C3%A9e" title="Cycle de l'urée">cycle de l'urée</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Découverte"><span id="D.C3.A9couverte"></span>Découverte</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Acide_aspartique&veaction=edit&section=1" title="Modifier la section : Découverte" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Acide_aspartique&action=edit&section=1" title="Modifier le code source de la section : Découverte"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'acide aspartique a été découvert en 1827 par Plisson, à partir de l'<a href="/wiki/Asparagine" title="Asparagine">asparagine</a>, elle-même isolée du jus d'asperge en 1806, en portant le jus à ébullition avec une <a href="/wiki/Base_(chimie)" title="Base (chimie)">base</a><sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite_crochet">[</span>7<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Rôle_et_fonctions"><span id="R.C3.B4le_et_fonctions"></span>Rôle et fonctions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Acide_aspartique&veaction=edit&section=2" title="Modifier la section : Rôle et fonctions" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Acide_aspartique&action=edit&section=2" title="Modifier le code source de la section : Rôle et fonctions"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'acide aspartique participe à la <a href="/wiki/Glucon%C3%A9ogen%C3%A8se" class="mw-redirect" title="Gluconéogenèse">gluconéogenèse</a> et il joue un rôle de substrat de la <a href="/wiki/Voie_m%C3%A9tabolique" title="Voie métabolique">voie</a> de <a href="/wiki/Biosynth%C3%A8se" title="Biosynthèse">biosynthèse</a> des <a href="/wiki/Pyrimidine" title="Pyrimidine">pyrimidines</a>. C'est un <a href="/wiki/Neurotransmetteur" title="Neurotransmetteur">neurotransmetteur</a><sup id="cite_ref-Nobutoshi_8-0" class="reference"><a href="#cite_note-Nobutoshi-8"><span class="cite_crochet">[</span>8<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite_crochet">[</span>9<span class="cite_crochet">]</span></a></sup> excitant du cerveau sous sa forme <a href="/wiki/M%C3%A9thylation" title="Méthylation">méthylée</a> <span class="nowrap">(<i>N</i>-méthyl-<small>D</small>-aspartate)</span>, activant les <a href="/wiki/R%C3%A9cepteur_NMDA" title="Récepteur NMDA">récepteurs NMDA</a>, qui sont des récepteurs au <a href="/wiki/Glutamate" class="mw-redirect" title="Glutamate">glutamate</a>. </p><p>L'acide D-aspartique, ainsi que son sel, le D-aspartate de sodium, ont des propriétés anabolisantes favorisant la production endogène de <a href="/wiki/Testost%C3%A9rone" title="Testostérone">testostérone</a> et de <a href="/wiki/Progest%C3%A9rone" title="Progestérone">progestérone</a>, ainsi que de l'<a href="/wiki/Hormone_lut%C3%A9inisante" title="Hormone lutéinisante">hormone lutéinisante</a><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite_crochet">[</span>10<span class="cite_crochet">]</span></a></sup>. Mais selon une revue systématique datant de 2017, cette augmentation du taux de testostérone dans le sang chez les humains n'est pas démontrée, à cause de résultats contradictoires et nécessite plus d'expérimentations<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite_crochet">[</span>11<span class="cite_crochet">]</span></a></sup>. </p><p>De plus, il améliorerait la qualité du sperme<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite_crochet">[</span>12<span class="cite_crochet">]</span></a></sup> et aurait de l’influence positive sur les capacités cognitives et la mémorisation chez l’humain<sup id="cite_ref-Nobutoshi_8-1" class="reference"><a href="#cite_note-Nobutoshi-8"><span class="cite_crochet">[</span>8<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Acide_aspartique_et_aspartame">Acide aspartique et aspartame</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Acide_aspartique&veaction=edit&section=3" title="Modifier la section : Acide aspartique et aspartame" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Acide_aspartique&action=edit&section=3" title="Modifier le code source de la section : Acide aspartique et aspartame"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'acide aspartique représente 40 % des produits de dégradation de l’<a href="/wiki/Aspartame" title="Aspartame">aspartame</a><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite_crochet">[</span>13<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Notes_et_références"><span id="Notes_et_r.C3.A9f.C3.A9rences"></span>Notes et références</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Acide_aspartique&veaction=edit&section=4" title="Modifier la section : Notes et références" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Acide_aspartique&action=edit&section=4" title="Modifier le code source de la section : Notes et références"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="references-small decimal" style="column-width:30em;"><ol class="references"> <li id="cite_note-ICSC-1"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-ICSC_1-0">a</a> <a href="#cite_ref-ICSC_1-1">b</a> <a href="#cite_ref-ICSC_1-2">c</a> <a href="#cite_ref-ICSC_1-3">d</a> <a href="#cite_ref-ICSC_1-4">e</a> et <a href="#cite_ref-ICSC_1-5">f</a></sup> </span><span class="reference-text"><a rel="nofollow" class="external text" href="https://www.ilo.org/dyn/icsc/showcard.display?p_lang=fr&p_card_id=1439">ACIDE L - ASPARTIQUE</a>, <a href="/wiki/Fiches_internationales_de_s%C3%A9curit%C3%A9_chimique" title="Fiches internationales de sécurité chimique">Fiches internationales de sécurité chimique</a> </span> </li> <li id="cite_note-2"><span class="mw-cite-backlink noprint"><a href="#cite_ref-2">↑</a> </span><span class="reference-text">Masse molaire calculée d’après <span class="ouvrage">« <a rel="nofollow" class="external text" href="http://www.chem.qmul.ac.uk/iupac/AtWt/"><cite style="font-style:normal;"><span class="lang-en" lang="en">Atomic weights of the elements 2007</span></cite></a> », sur <span class="italique">www.chem.qmul.ac.uk</span></span>.</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink noprint"><a href="#cite_ref-3">↑</a> </span><span class="reference-text"> <span class="ouvrage" id="Carey2014"><span class="ouvrage" id="Francis_A._Carey2014"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Francis A. Carey, « <a rel="nofollow" class="external text" href="http://www.chem.ucalgary.ca/courses/351/Carey5th/Ch27/ch27-1-4-2.html"><cite style="font-style:normal;" lang="en">Table of pKa and pI values</cite></a> », sur <span class="italique">Département de chimie de l'<a href="/wiki/Universit%C3%A9_de_Calgary" title="Université de Calgary">université de Calgary</a></span>, <time>2014</time> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2015-07-26" data-sort-value="2015-07-26">26 juillet 2015</time>)</small></span></span>.</span> </li> <li id="cite_note-4"><span class="mw-cite-backlink noprint"><a href="#cite_ref-4">↑</a> </span><span class="reference-text"> <span class="ouvrage" id="Beals,_L._Gross,_S._Harrell"><span class="ouvrage" id="M._Beals,_L._Gross,_S._Harrell"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> M. Beals, L. Gross, S. Harrell, « <a rel="nofollow" class="external text" href="http://www.tiem.utk.edu/~gross/bioed/webmodules/aminoacid.htm"><cite style="font-style:normal;" lang="en">Amino Acid Frequency</cite></a> », sur <span class="italique">The Institute for Environmental Modeling (TIEM) à l'<a href="/wiki/Universit%C3%A9_du_Tennessee" title="Université du Tennessee">université du Tennessee</a></span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2015-07-26" data-sort-value="2015-07-26">26 juillet 2015</time>)</small></span></span>.</span> </li> <li id="cite_note-reciprocalnet-5"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-reciprocalnet_5-0">a</a> <a href="#cite_ref-reciprocalnet_5-1">b</a> et <a href="#cite_ref-reciprocalnet_5-2">c</a></sup> </span><span class="reference-text"><span class="ouvrage">« <a rel="nofollow" class="external text" href="http://www.reciprocalnet.org/recipnet/showsampledetailed.jsp?sampleId=27344608"><cite style="font-style:normal;">Aspartic acid</cite></a> », sur <span class="italique">reciprocalnet.org</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2009-12-12" data-sort-value="2009-12-12">12 décembre 2009</time>)</small></span>.</span> </li> <li id="cite_note-Reptox-6"><span class="mw-cite-backlink noprint"><a href="#cite_ref-Reptox_6-0">↑</a> </span><span class="reference-text">« <a rel="nofollow" class="external text" href="http://www.reptox.csst.qc.ca/DetailSimdut.asp?no_produit=107771&langue=F">Acide aspartique (l-)</a> » dans la base de données de produits chimiques <i>Reptox</i> de la <a href="/wiki/Commission_de_la_sant%C3%A9_et_de_la_s%C3%A9curit%C3%A9_du_travail" title="Commission de la santé et de la sécurité du travail">CSST</a> (organisme québécois responsable de la sécurité et de la santé au travail), consulté le 25 avril 2009</span> </li> <li id="cite_note-7"><span class="mw-cite-backlink noprint"><a href="#cite_ref-7">↑</a> </span><span class="reference-text"> <span class="ouvrage" id="PlimmerHopkins1912"><span class="ouvrage" id="R.H.A._PlimmerF.G._Hopkins1912">R.H.A. Plimmer (<abbr class="abbr" title="directeur de publication">dir.</abbr>) et F.G. Hopkins (<abbr class="abbr" title="directeur de publication">dir.</abbr>), <cite class="italique">The chemical composition of the proteins</cite>, <abbr class="abbr" title="volume">vol.</abbr> Part I. Analysis, London, Longmans, Green and Co., <time>1912</time>, 2nd <abbr class="abbr" title="édition">éd.</abbr> (<abbr class="abbr" title="première">1<sup>re</sup></abbr> <abbr class="abbr" title="édition">éd.</abbr> 1908) <small style="line-height:1em;">(<a rel="nofollow" class="external text" href="https://books.google.com/?id=7JM8AAAAIAAJ&pg=PA112">lire en ligne</a>)</small>, <abbr class="abbr" title="page">p.</abbr> 112<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+chemical+composition+of+the+proteins&rft.place=London&rft.pub=Longmans%2C+Green+and+Co.&rft.edition=2nd&rft.aulast=Plimmer&rft.aufirst=R.H.A.&rft.au=F.G.+Hopkins&rft.date=1912&rft.volume=Part+I.+Analysis&rft.pages=112&rft_id=https%3A%2F%2Fbooks.google.com%2F%3Fid%3D7JM8AAAAIAAJ%26pg%3DPA112&rfr_id=info%3Asid%2Ffr.wikipedia.org%3AAcide+aspartique"></span></span></span>.</span> </li> <li id="cite_note-Nobutoshi-8"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-Nobutoshi_8-0">a</a> et <a href="#cite_ref-Nobutoshi_8-1">b</a></sup> </span><span class="reference-text"><span class="ouvrage" id="OtaShiSweedler2012"><span class="ouvrage" id="Nobutoshi_OtaTing_ShiJonathan_V._Sweedler2012">Nobutoshi <span class="nom_auteur">Ota</span>, Ting <span class="nom_auteur">Shi</span> et Jonathan V. <span class="nom_auteur">Sweedler</span>, « <cite style="font-style:normal">D-aspartate acts as a signaling molecule in nervous and neuroendocrine systems</cite> », <i>Amino acids</i>, <abbr class="abbr" title="volume">vol.</abbr> 43,‎ <time class="nowrap" datetime="2012-11-01" data-sort-value="2012-11-01"><abbr class="abbr" title="premier">1<sup>er</sup></abbr> novembre 2012</time>, <abbr class="abbr" title="pages">p.</abbr> <span class="nowrap">1873–1886</span> <small style="line-height:1em;">(<a href="/wiki/International_Standard_Serial_Number" title="International Standard Serial Number">ISSN</a> <span class="plainlinks noarchive"><a rel="nofollow" class="external text" href="https://portal.issn.org/resource/issn/0939-4451">0939-4451</a></span>, <a href="/wiki/PubMed" title="PubMed">PMID</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/22872108">22872108</a></span>, <a href="/wiki/PubMed_Central" title="PubMed Central">PMCID</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/3555687">3555687</a></span>, <a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://dx.doi.org/10.1007/s00726-012-1364-1">10.1007/s00726-012-1364-1</a></span>, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555687/">lire en ligne</a>, consulté le <time class="nowrap" datetime="2016-03-31" data-sort-value="2016-03-31">31 mars 2016</time>)</small><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=D-aspartate+acts+as+a+signaling+molecule+in+nervous+and+neuroendocrine+systems&rft.jtitle=Amino+acids&rft.aulast=Ota&rft.aufirst=Nobutoshi&rft.au=Shi%2C+Ting&rft.au=Sweedler%2C+Jonathan+V.&rft.date=2012-11-01&rft.volume=43&rft.pages=1873%E2%80%931886&rft.issn=0939-4451&rft_id=info%3Adoi%2F10.1007%2Fs00726-012-1364-1&rft_id=info%3Apmid%2F22872108&rfr_id=info%3Asid%2Ffr.wikipedia.org%3AAcide+aspartique"></span></span></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink noprint"><a href="#cite_ref-9">↑</a> </span><span class="reference-text"><span class="ouvrage" id="D'Aniello2007"><span class="ouvrage" id="Antimo_D'Aniello2007">Antimo <span class="nom_auteur">D'Aniello</span>, « <cite style="font-style:normal">d-Aspartic acid: An endogenous amino acid with an important neuroendocrine role</cite> », <i>Brain Research Reviews</i>, <abbr class="abbr" title="volume">vol.</abbr> 53,‎ <time class="nowrap" datetime="2007-02-01" data-sort-value="2007-02-01"><abbr class="abbr" title="premier">1<sup>er</sup></abbr> février 2007</time>, <abbr class="abbr" title="pages">p.</abbr> <span class="nowrap">215–234</span> <small style="line-height:1em;">(<a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/j.brainresrev.2006.08.005">10.1016/j.brainresrev.2006.08.005</a></span>, <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/article/pii/S0165017306001020">lire en ligne</a>, consulté le <time class="nowrap" datetime="2016-03-31" data-sort-value="2016-03-31">31 mars 2016</time>)</small><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=d-Aspartic+acid%3A+An+endogenous+amino+acid+with+an+important+neuroendocrine+role&rft.jtitle=Brain+Research+Reviews&rft.aulast=D%27Aniello&rft.aufirst=Antimo&rft.date=2007-02-01&rft.volume=53&rft.pages=215%E2%80%93234&rft_id=info%3Adoi%2F10.1016%2Fj.brainresrev.2006.08.005&rfr_id=info%3Asid%2Ffr.wikipedia.org%3AAcide+aspartique"></span></span></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink noprint"><a href="#cite_ref-10">↑</a> </span><span class="reference-text"><span class="ouvrage" id="TopoSoricelliD'AnielloRonsini2009"><span class="ouvrage" id="Enza_TopoAndrea_SoricelliAntimo_D'AnielloSalvatore_Ronsini2009"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Enza <span class="nom_auteur">Topo</span>, Andrea <span class="nom_auteur">Soricelli</span>, Antimo <span class="nom_auteur">D'Aniello</span> et Salvatore <span class="nom_auteur">Ronsini</span>, « <cite style="font-style:normal" lang="en">The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats</cite> », <i><span class="lang-en" lang="en">Reproductive Biology and Endocrinology</span></i>, <abbr class="abbr" title="volume">vol.</abbr> 7,‎ <time class="nowrap" datetime="2009-10-27" data-sort-value="2009-10-27">27 octobre 2009</time> <small style="line-height:1em;">(<a href="/wiki/PubMed" title="PubMed">PMID</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/19860889">19860889</a></span>, <a href="/wiki/PubMed_Central" title="PubMed Central">PMCID</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/2774316">2774316</a></span>, <a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://dx.doi.org/10.1186/1477-7827-7-120">10.1186/1477-7827-7-120</a></span>, <a rel="nofollow" class="external text" href="http://www.rbej.com/content/7/1/120">lire en ligne</a>, consulté le <time class="nowrap" datetime="2016-03-31" data-sort-value="2016-03-31">31 mars 2016</time>)</small><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+role+and+molecular+mechanism+of+D-aspartic+acid+in+the+release+and+synthesis+of+LH+and+testosterone+in+humans+and+rats&rft.jtitle=Reproductive+Biology+and+Endocrinology&rft.aulast=Topo&rft.aufirst=Enza&rft.au=Soricelli%2C+Andrea&rft.au=D%27Aniello%2C+Antimo&rft.au=Ronsini%2C+Salvatore&rft.date=2009-10-27&rft.volume=7&rft_id=info%3Adoi%2F10.1186%2F1477-7827-7-120&rft_id=info%3Apmid%2F19860889&rfr_id=info%3Asid%2Ffr.wikipedia.org%3AAcide+aspartique"></span></span></span></span> </li> <li id="cite_note-11"><span class="mw-cite-backlink noprint"><a href="#cite_ref-11">↑</a> </span><span class="reference-text"><span class="ouvrage" id="RoshanzamirSafavi2017"><span class="ouvrage" id="Farzad_RoshanzamirSeyyed_Morteza_Safavi2017">Farzad <span class="nom_auteur">Roshanzamir</span> et Seyyed Morteza <span class="nom_auteur">Safavi</span>, « <cite style="font-style:normal">The putative effects of D-Aspartic acid on blood testosterone levels: A systematic review</cite> », <i>International Journal of Reproductive Biomedicine</i>, <abbr class="abbr" title="volume">vol.</abbr> 15, <abbr class="abbr" title="numéro">n<sup>o</sup></abbr> 1,‎ <time class="nowrap" datetime="2017-01" data-sort-value="2017-01">janvier 2017</time>, <abbr class="abbr" title="pages">p.</abbr> <span class="nowrap">1–10</span> <small style="line-height:1em;">(<a href="/wiki/International_Standard_Serial_Number" title="International Standard Serial Number">ISSN</a> <span class="plainlinks noarchive"><a rel="nofollow" class="external text" href="https://portal.issn.org/resource/issn/2476-4108">2476-4108</a></span>, <a href="/wiki/PubMed" title="PubMed">PMID</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/28280794">28280794</a></span>, <a href="/wiki/PubMed_Central" title="PubMed Central">PMCID</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/5340133">5340133</a></span>, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340133/">lire en ligne</a>, consulté le <time class="nowrap" datetime="2023-12-26" data-sort-value="2023-12-26">26 décembre 2023</time>)</small><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+putative+effects+of+D-Aspartic+acid+on+blood+testosterone+levels%3A+A+systematic+review&rft.jtitle=International+Journal+of+Reproductive+Biomedicine&rft.issue=1&rft.aulast=Roshanzamir&rft.aufirst=Farzad&rft.au=Safavi%2C+Seyyed+Morteza&rft.date=2017-01&rft.volume=15&rft.pages=1%E2%80%9310&rft.issn=2476-4108&rft_id=info%3Apmid%2F28280794&rfr_id=info%3Asid%2Ffr.wikipedia.org%3AAcide+aspartique"></span></span></span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink noprint"><a href="#cite_ref-12">↑</a> </span><span class="reference-text"><span class="ouvrage" id="D’AnielloRonsiniNotariGrieco2012"><span class="ouvrage" id="Gemma_D’AnielloSalvatore_RonsiniTiziana_NotariNatascia_Grieco2012"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Gemma <span class="nom_auteur">D’Aniello</span>, Salvatore <span class="nom_auteur">Ronsini</span>, Tiziana <span class="nom_auteur">Notari</span>, Natascia <span class="nom_auteur">Grieco</span> <i><abbr class="abbr" title="et alii (et d’autres)">et al.</abbr></i>, « <cite style="font-style:normal" lang="en">D-Aspartate, a Key Element for the Improvement of Sperm Quality</cite> », <i><span class="lang-en" lang="en">Advances in Sexual Medicine</span></i>, <abbr class="abbr" title="volume">vol.</abbr> 2, <abbr class="abbr" title="numéro">n<sup>o</sup></abbr> 4,‎ <time class="nowrap" datetime="2012-10" data-sort-value="2012-10">octobre 2012</time>, <abbr class="abbr" title="pages">p.</abbr> <span class="nowrap">47–53</span> <small style="line-height:1em;">(<a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://dx.doi.org/10.4236/asm.2012.24008">10.4236/asm.2012.24008</a></span>, <a rel="nofollow" class="external text" href="https://dx.doi.org/10.4236/asm.2012.24008">lire en ligne</a>)</small><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=D-Aspartate%2C+a+Key+Element+for+the+Improvement+of+Sperm+Quality&rft.jtitle=Advances+in+Sexual+Medicine&rft.issue=4&rft.aulast=D%E2%80%99Aniello&rft.aufirst=Gemma&rft.au=Ronsini%2C+Salvatore&rft.au=Notari%2C+Tiziana&rft.au=Grieco%2C+Natascia&rft.date=2012-10&rft.volume=2&rft.pages=47%E2%80%9353&rft_id=info%3Adoi%2F10.4236%2Fasm.2012.24008&rfr_id=info%3Asid%2Ffr.wikipedia.org%3AAcide+aspartique"></span></span></span></span> </li> <li id="cite_note-13"><span class="mw-cite-backlink noprint"><a href="#cite_ref-13">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-format format-pdf" title="Document au format Portable Document Format (PDF)">[PDF]</abbr> <a rel="nofollow" class="external text" href="http://julientap.free.fr/travail_fichiers/aspartame.pdf">julientap.free.fr</a>)</span> </li> </ol> </div> <div class="mw-heading mw-heading2"><h2 id="Voir_aussi">Voir aussi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Acide_aspartique&veaction=edit&section=5" title="Modifier la section : Voir aussi" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Acide_aspartique&action=edit&section=5" title="Modifier le code source de la section : Voir aussi"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Aspartate_transaminase" class="mw-redirect" title="Aspartate transaminase">aspartate transaminase</a></li> <li><a href="/wiki/Datation_par_rac%C3%A9misation_des_acides_amin%C3%A9s" title="Datation par racémisation des acides aminés">Datation par racémisation des acides aminés</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Lien_externe">Lien externe</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Acide_aspartique&veaction=edit&section=6" title="Modifier la section : Lien externe" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Acide_aspartique&action=edit&section=6" title="Modifier le code source de la section : Lien externe"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <a rel="nofollow" class="external free" href="http://www.chemie.fu-berlin.de/chemistry/bio/aminoacid/asp_en.html">http://www.chemie.fu-berlin.de/chemistry/bio/aminoacid/asp_en.html</a></li></ul> <div class="navbox-container" style="clear:both;"> <table class="navbox collapsible noprint autocollapse" style=""> <tbody><tr><th class="navbox-title" colspan="3" style=""><div style="float:left; width:6em; text-align:left"><div class="noprint plainlinks nowrap tnavbar" style="padding:0; font-size:xx-small; color:var(--color-emphasized, #000000);"><a href="/wiki/Mod%C3%A8le:Palette_Acides_amin%C3%A9s" title="Modèle:Palette Acides aminés"><abbr class="abbr" title="Voir ce modèle.">v</abbr></a> · <a class="external text" href="https://fr.wikipedia.org/w/index.php?title=Mod%C3%A8le:Palette_Acides_amin%C3%A9s&action=edit"><abbr class="abbr" title="Modifier ce modèle. Merci de prévisualiser avant de sauvegarder.">m</abbr></a></div></div><div style="font-size:110%"><a href="/wiki/Acide_amin%C3%A9" title="Acide aminé">Acides aminés</a></div></th> </tr> <tr> <th class="navbox-group" style="width:200px;"><a href="/wiki/Acide_amin%C3%A9_prot%C3%A9inog%C3%A8ne" title="Acide aminé protéinogène">Acide aminé protéinogène</a></th> <td class="navbox-list" style=""><table class="navbox-subgroup" style=""> <tbody><tr> <th class="navbox-group" style=""><a href="/wiki/Compos%C3%A9_aliphatique" title="Composé aliphatique">Aliphatique</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Acide_amin%C3%A9_ramifi%C3%A9" title="Acide aminé ramifié">Acide aminé ramifié</a> <ul><li><a href="/wiki/Valine" title="Valine">Valine</a></li> <li><a href="/wiki/Isoleucine" title="Isoleucine">Isoleucine</a></li> <li><a href="/wiki/Leucine" title="Leucine">Leucine</a></li></ul></li> <li><a href="/wiki/M%C3%A9thionine" title="Méthionine">Méthionine</a></li> <li><a href="/wiki/Alanine" title="Alanine">Alanine</a></li> <li><a href="/wiki/Proline" title="Proline">Proline</a></li> <li><a href="/wiki/Glycine_(acide_amin%C3%A9)" title="Glycine (acide aminé)">Glycine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Acide_amin%C3%A9#Acides_aminés_aromatiques" title="Acide aminé">Aromatique</a></th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Ph%C3%A9nylalanine" title="Phénylalanine">Phénylalanine</a></li> <li><a href="/wiki/Tyrosine" title="Tyrosine">Tyrosine</a></li> <li><a href="/wiki/Tryptophane" title="Tryptophane">Tryptophane</a></li> <li><a href="/wiki/Histidine" title="Histidine">Histidine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Polarit%C3%A9_(chimie)" title="Polarité (chimie)">Polaire</a>, non chargé</th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Asparagine" title="Asparagine">Asparagine</a></li> <li><a href="/wiki/Glutamine" title="Glutamine">Glutamine</a></li> <li><a href="/wiki/S%C3%A9rine" title="Sérine">Sérine</a></li> <li><a href="/wiki/Thr%C3%A9onine" title="Thréonine">Thréonine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">Charge positive (<a href="/wiki/Constante_d%27acidit%C3%A9" title="Constante d'acidité">p<i>K</i><sub>a</sub></a>)</th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Lysine" title="Lysine">Lysine</a> (≈10,8)</li> <li><a href="/wiki/Arginine" title="Arginine">Arginine</a> (≈12,5)</li> <li><a href="/wiki/Histidine" title="Histidine">Histidine</a> (≈6.1)</li> <li><a href="/wiki/Pyrrolysine" title="Pyrrolysine">Pyrrolysine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">Charge négative (<a href="/wiki/Constante_d%27acidit%C3%A9" title="Constante d'acidité">p<i>K</i><sub>a</sub></a>)</th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a class="mw-selflink selflink">Aspartate</a> (≈3,9)</li> <li><a href="/wiki/Acide_glutamique" title="Acide glutamique">Glutamate</a> (≈4,1)</li> <li><a href="/wiki/S%C3%A9l%C3%A9nocyst%C3%A9ine" title="Sélénocystéine">Sélénocystéine</a> (≈5,4)</li> <li><a href="/wiki/Cyst%C3%A9ine" title="Cystéine">Cystéine</a> (≈8,3)</li> <li><a href="/wiki/Tyrosine" title="Tyrosine">Tyrosine</a> (≈10,1)</li></ul> </div></td> </tr> </tbody></table></td> <td class="navbox-image" rowspan="2" style="vertical-align:middle;padding-left:7px"><figure class="mw-halign-right" typeof="mw:File"><a href="/wiki/Fichier:L-amino_acid_any.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/L-amino_acid_any.png/145px-L-amino_acid_any.png" decoding="async" width="145" height="127" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/L-amino_acid_any.png/218px-L-amino_acid_any.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0e/L-amino_acid_any.png/290px-L-amino_acid_any.png 2x" data-file-width="728" data-file-height="640" /></a><figcaption></figcaption></figure></td> </tr> <tr> <th class="navbox-group" style="width:200px;"><a href="/wiki/Acide_amin%C3%A9_non_prot%C3%A9inog%C3%A8ne" title="Acide aminé non protéinogène">Acide aminé non protéinogène</a></th> <td class="navbox-list navbox-even" style=""><div class="liste-horizontale"> <ul><li><a href="/wiki/Acide_amin%C3%A9_non_prot%C3%A9inog%C3%A8ne#Acides_aminés_non_protéinogènes_présents_dans_des_protéines" title="Acide aminé non protéinogène">Acides aminés non protéinogènes présents dans des protéines</a></li> <li><a href="/wiki/Acide_amin%C3%A9_non_prot%C3%A9inog%C3%A8ne#Autres_acides_aminés_non_protéinogènes" title="Acide aminé non protéinogène">Autres acides aminés non protéinogènes</a></li></ul> </div></td> </tr> <tr> <td class="navbox-banner" style="" colspan="3"><div class="liste-horizontale"> <ul><li><a href="/wiki/Prot%C3%A9ine" title="Protéine">Protéine</a></li> <li><a href="/wiki/Peptide" title="Peptide">Peptide</a></li> <li><a href="/wiki/Code_g%C3%A9n%C3%A9tique" title="Code génétique">Code génétique</a></li> <li><a href="/wiki/Acide_amin%C3%A9_essentiel" title="Acide aminé essentiel">Acide aminé essentiel</a></li> <li><a href="/wiki/Acide_amin%C3%A9_glucoformateur" title="Acide aminé glucoformateur">Acide aminé glucoformateur</a></li> <li><a href="/wiki/Acide_amin%C3%A9_c%C3%A9toformateur" title="Acide aminé cétoformateur">Acide aminé cétoformateur</a></li> <li><a href="/wiki/Acide_amin%C3%A9#Acides_aminés_non_standard" title="Acide aminé">Acide aminé non standard</a></li></ul> </div></td></tr></tbody></table> </div> <ul id="bandeau-portail" class="bandeau-portail"><li><span class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a href="/wiki/Portail:Chimie" title="Portail de la chimie"><img alt="icône décorative" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/Nuvola_apps_edu_science.svg/24px-Nuvola_apps_edu_science.svg.png" decoding="async" width="24" height="24" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/Nuvola_apps_edu_science.svg/36px-Nuvola_apps_edu_science.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/59/Nuvola_apps_edu_science.svg/48px-Nuvola_apps_edu_science.svg.png 2x" data-file-width="128" data-file-height="128" /></a></span></span> <span class="bandeau-portail-texte"><a href="/wiki/Portail:Chimie" title="Portail:Chimie">Portail de la chimie</a></span> </span></li> <li><span class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a href="/wiki/Portail:Biochimie" title="Portail de la biochimie"><img alt="icône décorative" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/19/Hemoglobin.jpg/26px-Hemoglobin.jpg" decoding="async" width="26" height="24" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/19/Hemoglobin.jpg/39px-Hemoglobin.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/19/Hemoglobin.jpg/52px-Hemoglobin.jpg 2x" data-file-width="418" data-file-height="386" /></a></span></span> <span class="bandeau-portail-texte"><a href="/wiki/Portail:Biochimie" title="Portail:Biochimie">Portail de la biochimie</a></span> </span></li> <li><span class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a href="/wiki/Portail:Biologie_cellulaire_et_mol%C3%A9culaire" title="Portail de la biologie cellulaire et moléculaire"><img alt="icône décorative" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cc/Red2.jpg/27px-Red2.jpg" decoding="async" width="27" height="24" class="mw-file-element" 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