Facilities | NorthStar Medical Radioisotopes, LLC

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data-image-src="https://www.northstarnm.com/wp-content/uploads/2021/05/bg-facilities-scaled.jpg" data-natural-width="898" data-natural-height="2560"></div> <div class="section-content "> <section class="h2_header_short"> <div class="container"> <div class="header-inner"> <a href="https://www.northstarnm.com/company/" class="h2_breadcrumb_link mb-2 md-blue">Company</a> <h1 class="mb-5">Our<br><span>Facilities</span></h1> <div class="h2_intro_box"> <p>NorthStar’s facilities in Wisconsin house our Company Headquarters and production, R&D and manufacturing, as well as all of our other departments.</p> </div> </div> </div> </section> <section class="r10_row_facilities pb-5"> <div class="container" id="beloit"> <div class="p-5 mb-3 bg-white-fade"> <div class="r10-bc mb-3"> <ul> <li><a href="#madison" class="md-blue" data-spy="scroll">Madison, WI</a></li> </ul> </div> <div class="r10-box-title mb-5 md-blue"> <h3><span>Company Headquarters</span> and<br>Primary Manufacturing Locations</h3> </div> <div class="r10-region-title mb-5 md-blue"> <h3>Beloit, <span>WI</span></h3> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2021/06/circle-hq_1.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title md-blue"> <h4>Corporate Headquarters </h4> </div> <div class="l-address"> <p>1800 Gateway Boulevard, Beloit, WI 53511</p> </div> <p>NorthStar鈥檚 corporate headquarters in Beloit house our executive, administrative, Quality Affairs/Regulatory Affairs, logistics and Copper-67 (Cu-67) production activities, customer care, and training teams.</p> </div> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2022/01/circle-Be-2-Dec-2021-01.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title md-blue"> <h4>Isotope Processing Facility </h4> </div> <div class="l-address"> <p>1800 Gateway Boulevard, Beloit, WI 53511</p> </div> <p>This 20,000 sq ft facility, completed in September 2019, is equipped with a chemical processing line, analytical testing and metallurgy laboratories, and radioactive storage. Regular production runs of Radiochemical Grade (RCG) Copper-67 (Cu-67) are conducted here. Currently, the building is undergoing a major infrastructure upgrade, including the addition of new processing lines and product hot cells. Additionally, work is in progress to retrofit previously installed hot cells, originally dedicated to the production of other isotopes, to enhance our Cu-67 output. These upgrades are part of our strategy to upscale processes and prepare for large-scale cGMP commercial production. Furthermore, this facility includes a cGMP-compliant CDMO suite for final dose products.</p> </div> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2021/05/location-beloit-3.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title md-blue"> <h4><span id="apf"></span> Copper-67 Accelerator Production Facility </h4> </div> <div class="l-address"> <p>1800 Gateway Boulevard, Beloit, WI 53511</p> </div> <p>Groundbreaking for this 30,000 sq. ft. facility took place in September 2019, and construction was completed in January 2021. The first pair of electron beam accelerators are operational and producing Cu-67 on a routine basis.</p> <p>NorthStar鈥檚 unique and proprietary electron accelerator production facility and processes are designed to optimize efficiency throughout the production cycle. This setup allows us the flexibility to produce batches of various sizes based on market demand.</p> <p>During the initial construction, site preparation was completed adjacent to the first building, allowing NorthStar to swiftly add up to three additional mirror-image accelerator facilities. These new facilities are planned to support the growing market demand for Cu-67 and other radioisotopes.</p> <div class="module-timeline"> <div class="timeline-container theme-gray-blue-black"> <div class="timeline-item status-complete"> <div class="timeline-date"> Sept 2019 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Accelerator Production facility groundbreaking </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Jan 2021 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Facility construction completed </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Apr 2021 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Delivery of electron accelerator pair </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Mid 2022 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Electron accelerator pair and associated equipment operational </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Mid 2023 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Initial production of radiochemical grade Cu-67 </div> </div> </div> </div> </div> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2024/01/Be4-04Jan2024-01.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title md-blue"> <h4>ACTINIUM-225 PRODUCTION FACILITY</h4> </div> <div class="l-address"> <p>1800 Gateway Boulevard, Beloit, WI 53511</p> </div> <p><a href="https://www.northstarnm.com/company/resource/unveiling-and-groundbreaking-event-september-2021/">Groundbreaking</a> for this 30,000+ sq ft first-of-its-kind Actinium-225 (Ac-225) Production facility, dedicated exclusively to commercial-scale production of non-carrier added (n.c.a.) Ac-225, was celebrated in <a href="https://www.northstarnm.com/northstar-medical-radioisotopes-expansion-event-unveils-advanced-radioisotope-production-equipment-and-breaks-ground-on-first-in-kind-therapeutic-radioisotope-production-facility/">September 2021</a>. The facility houses a Rhodotron庐 TT300 HE electron beam accelerator used solely for the production of Ac-225. This marks the <a href="https://www.northstarnm.com/northstar-medical-radioisotopes-and-iba-sign-contract-for-rhodotron-electron-beam-accelerator-for-commercial-production-of-therapeutic-radioisotope-actinium-225-ac-225/">third electron accelerator NorthStar has purchased from IBA</a>. Utilizing design concepts and key learnings from our Mo-99 and Cu-67 programs, this facility will allow for more efficient and expedited completion timelines, with potential future expansion plans in mind.</p> <p>Construction began in early 2022 with initial production of radiochemical grade Ac-225 planned for 2025. We expect submission of the Drug Master File to the U.S. Food and Drug Administration (U.S. FDA) in 2025.</p> <div class="module-timeline"> <div class="timeline-container theme-gray-blue-black"> <div class="timeline-item status-complete"> <div class="timeline-date"> Sept 2021 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Facility Groundbreaking </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Nov 2021 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Orders placed for accelerators and essential long-lead items </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Early 2022 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Construction begins </div> </div> <div class="timeline-item "> <div class="timeline-date"> Q1 2025 </div> <div class="timeline-status"> <div class="timeline-status-inner"> </div> </div> <div class="timeline-content"> Initial production of radiochemical grade Ac-225 </div> </div> <div class="timeline-item "> <div class="timeline-date"> LATE 2025 </div> <div class="timeline-status"> <div class="timeline-status-inner"> </div> </div> <div class="timeline-content"> Drug Master File Submitted to FDA </div> </div> </div> </div> </div> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2024/10/Be5-22OCT2024-01.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title md-blue"> <h4>RADIOPHARMACEUTICAL CDMO/CMO FACILITY</h4> </div> <div class="l-address"> <p>1800 Gateway Boulevard, Beloit, WI 53511</p> </div> <p>NorthStar Medical Radioisotopes will be the <strong>first and only</strong> U.S. company housing world class, commercial-scale, multi-radioisotope production and radiopharmaceutical development services on one campus. Our new Radiopharmaceutical CDMO facility is located on our 55-acre campus in Beloit, Wisconsin, enabling collaborator companies to realize the logistical, regulatory and other efficiency benefits afforded by a single site location.</p> <p>Groundbreaking for the new 52,000 sq ft, state-of-the-art Radiopharmaceutical CDMO facility occurred in November 2022. The facility is purpose-engineered to meet growing demands for therapeutic and diagnostic radiopharmaceuticals. Also designed with the needs of our partner companies in mind, the facility will offer the flexibility needed to support advancement of their products, from development to commercialization.</p> <div class="module-timeline"> <div class="timeline-container theme-gray-blue-black"> <div class="timeline-item status-complete"> <div class="timeline-date"> Oct 2022 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Facility Groundbreaking </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Early 2023 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Construction begins </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> July 2024 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Construction complete </div> </div> <div class="timeline-item "> <div class="timeline-date"> Jan 2025 </div> <div class="timeline-status"> <div class="timeline-status-inner"> </div> </div> <div class="timeline-content"> CDMO/CMO Production Operations Launch </div> </div> </div> </div> </div> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2024/08/addl-fac-30Aug2024-01.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title md-blue"> <h4>Additional Facilities</h4> </div> <div class="l-address"> <p>1800 Gateway Boulevard, Beloit, WI 53511</p> </div> <p>NorthStar鈥檚 55-acre Beloit campus has space for additional facilities that will support the production of other isotopes and related products as their development progresses.</p> </div> </div> </div> </div> <div class="container" id="madison"> <div class="p-5 mb-3 bg-xlt-blue"> <div class="r10-bc mb-3"> <ul> <li><a href="#beloit" class="white" data-spy="scroll">Beloit, WI</a></li> </ul> </div> <div class="r10-region-title mb-5 white"> <h3>Madison, <span>WI</span></h3> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2021/05/location-madison-1.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title white"> <h4>Research and Development</h4> </div> <div class="l-address"> <p>5249 Femrite Drive, Madison, WI 53718</p> </div> <p>Femrite Drive is our 10,000 ft<sup>2</sup> facility that is the Research and Development center of expertise for our product development engineering, microbiology and science teams. This facility also houses state-of-the-art microbiology and radiochemistry laboratories to support analytical and product testing.</p> </div> </div> <div class="row mb-5"> <div class="col-sm-3 text-center"> <img src="https://www.northstarnm.com/wp-content/uploads/2021/05/location-madison-2.png" alt="" class="img-fluid w-75 mb-4" /> </div> <div class="col-sm-9"> <div class="l-title white"> <h4>Research and Development</h4> </div> <div class="l-address"> <p>3060 Progress Road, Madison, WI 53716</p> </div> <p>Progress Road is a 10,000 ft<sup>2</sup> facility that is the Research and Development center of expertise for our isotope production equipment and includes our process development engineering, material testing and chemistry development teams. This facility also houses state-of-the-art equipment for developing, testing and upgrading our novel isotope processing equipment.</p> </div> </div> </div> </div> </section> </div> </section> <section class="section-bg bg-md-blue" > <div class="section-content "> <section class="r7_row_multicolumns py-0 footer-cta" > <div class="container"> <div class="row"> <div class="col-12 relative d-flex flex-column "> <div class="row py-short align-items-center "> <div class="col-md-3 "> <h2 class="title mb-4 "> PARTNERING<br>WITH<br><span>NORTHSTAR</span> </h2>  </div> <div class="col-md-3 text-center"> <div class="featured-img"> <img src="https://www.northstarnm.com/wp-content/uploads/2021/09/circle-hq.png" class=" w-75 img-fluid mb-5 mb-lg-0" alt="" /> </div> </div> <div class="col-md-3 "> <div class="copy mb-4 mb-md-0"> <p>We actively seek partners to expand our presence in the marketplace. Please contact Frank Scholz or Paul Estrem for more information.</p> </div>  </div> <div class="col-md-3 "> <div class="copy mb-4 mb-md-0"> <p> </p> <p><strong class="bright-green">FRANK SCHOLZ</strong><br /> <a class="white" href="/cdn-cgi/l/email-protection#c4a2b7a7acaba8be84aaabb6b0acb7b0a5b6aaa9eaa7aba9"><span class="__cf_email__" data-cfemail="177164747f787b6d57797865637f64637665797a3974787a">[email protected]</span></a></p> <p><strong class="bright-green">PAUL ESTREM</strong><br /> <a class="white" href="/cdn-cgi/l/email-protection#b6c6d3c5c2c4d3dbf6d8d9c4c2dec5c2d7c4d8db98d5d9db"><span class="__cf_email__" data-cfemail="176772646365727a57797865637f64637665797a3974787a">[email protected]</span></a></p> <p> </p> </div>  </div> </div> </div> </div> </div> </section> </div> </section> </div> <footer class="py-5"> <div class="container"> <div class="row"> <div class="col-12 col-md-4 mb-4 mb-md-0 py-md-2"> <p class="footer-brand"><img src="https://www.northstarnm.com/wp-content/themes/northstar/img/logo-w.svg" alt="NorthStar Medical Radioisotopes, LLC" class="w-100 img-fluid" /></p> <div class="contact-box"> <p>1800 Gateway Boulevard<br /> Beloit, WI 53511<br /> <strong>Phone:</strong> <a href="tel:8444386659">(844) 438-6659</a><br /> <strong>Phone:</strong> <a href="tel:6083138000">(608) 313-8000</a></p> </div> </div> <div class="col-md-4 py-md-2 mb-4 mb-md-0"> <div class="menu-main-menu-container"><ul id="menu-main-menu-2" class="menu" itemscope itemtype="http://www.schema.org/SiteNavigationElement"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-12125"><a href="https://www.northstarnm.com/radiopharmaceutical-therapy/">Radiopharmaceutical Therapy</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-12604"><a href="https://www.northstarnm.com/cdmo-cmo/">CDMO/CMO</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-10982"><a href="https://www.northstarnm.com/development/">Development</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page current-page-ancestor current-menu-ancestor current-menu-parent current-page-parent current_page_parent current_page_ancestor menu-item-10981"><a href="https://www.northstarnm.com/company/">Company</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-10980"><a href="https://www.northstarnm.com/careers/">Careers</a></li> <li class="searchlink menu-item menu-item-type-custom menu-item-object-custom menu-item-10984"><a href="#search"><i class="fas fa-search"></i> <span class="navhide">Search</span></a></li> </ul></div> </div> <div class="col-12 col-md-4 mb-4 mb-md-0 border-left px-md-4 py-md-2"> <div class="f-col-title"> HOW CAN WE HELP? </div> <div class="f-col-content"> <p>Questions about our company, products, supply solutions, careers or anything else?</p> </div> <div class="f-col-link"> <a href="https://www.northstarnm.com/company/contact-us/" target="" class="btn btn-wire">Contact Us</a> </div> <div class="inline-links"> <ul class="social-links"> <li><a href="https://www.linkedin.com/company/northstar-medical-radioisotopes-llc/" target="_blank" title=""><span class="social-text">LinkedIn</span><span class="fa-stack" style="vertical-align: top;"> <i class="fas fa-circle fa-stack-2x"></i> <i class="fab fa-linkedin-in fa-stack-1x fa-inverse"></i> </span></a></li> <li><a href="https://www.instagram.com/northstarmedicalradioisotopes/" target="_blank" title=""><span class="social-text">Instagram</span><span class="fa-stack" style="vertical-align: top;"> <i class="fas fa-circle fa-stack-2x"></i> <i class="fab fa-instagram fa-stack-1x fa-inverse"></i> </span></a></li> </ul> </div> </div> <div class="col-12 footer-copyright py-3 mb-5 white"> 漏<script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script>var CurrentYear = new Date().getFullYear(); document.write(CurrentYear);</script> NMR. 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