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Monday, March 17, 2025</div></section><div id="section-2" class="author-show main-body page-authors-show"> <div id="breadcrumbs" class="breadcrumbs"><a class="" href="/">Home</a> » <a class="" href="https://www.bioworld.com/authors">Authors</a> » Tamra Sami</div> <div class="author-bio"> <div class="detail "> <h1 class="headline author-name"><a href="https://www.bioworld.com/authors/49-tamra-sami">Tamra Sami</a></h1> <div class="abstract"></div> <div class="link position"> </div> <div class="link articles"> <a href="https://www.bioworld.com/authors/49-tamra-sami/articles">Articles</a> </div> </div> </div> <div class="author-tab-list box1"><div class="records articles-list"> <h3 class="feature-title articles-list__title">ARTICLES</h3> <div class="articles-list__row"> <article class="record article-summary "> <div class="article-summary__details "> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/718249-visen-announces-hkd603m-hong-kong-ipo">Visen announces HKD$603M Hong Kong IPO</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 14, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">Visen Pharmaceuticals Co. Ltd. announced its initial public offering (IPO) on the Hong Kong Stock exchange (HKEX) to raise roughly HKD$603.3 million (US$77.6 million) to advance its pipeline of endocrinology assets.<br /></div><a title="Visen announces HKD$603M Hong Kong IPO" class="more" href="https://www.bioworld.com/articles/718249-visen-announces-hkd603m-hong-kong-ipo">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Australian patient first to leave hospital with Bivacor TAH" class="url" rel="" target="" href="https://www.bioworld.com/articles/717906-australian-patient-first-to-leave-hospital-with-bivacor-tah"><img width="650" height="488" alt="3D illustration of Bivacor implanted in chest" title="3D illustration of Bivacor implanted in chest" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BMT-source/2021/08-06-Bivacor-implanted.png?height=488&t=1628284543&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/717906-australian-patient-first-to-leave-hospital-with-bivacor-tah">Australian patient first to leave hospital with Bivacor TAH</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 13, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">An Australian man in his 40s with severe heart failure was implanted with a Bivacor Inc. total artificial heart (TAH) and has been discharged from the hospital. He remained at home with the artificial heart for 100 days until he received a transplant earlier this week.<br /></div><a title="Australian patient first to leave hospital with Bivacor TAH" class="more" href="https://www.bioworld.com/articles/717906-australian-patient-first-to-leave-hospital-with-bivacor-tah">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/718122-ono-scoops-ionis-hematology-candidate-sapablursen-for-up-to-940m">Ono scoops Ionis' hematology candidate sapablursen for up to $940M</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 12, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">Ono Pharmaceutical Co. Ltd. struck a licensing deal with Ionis Pharmaceuticals Inc. for sapablursen, which is in phase II trials for polycythemia vera. Under terms, Osaka, Japan-based Ono gains an exclusive license to develop and commercialize sapablursen worldwide. Carlsbad, Calif.-based Ionis will be responsible for completing the ongoing phase II Imprssion study, while Ono will be responsible for subsequent development, regulatory filings and commercialization.<br /></div><a title="Ono scoops Ionis' hematology candidate sapablursen for up to $940M" class="more" href="https://www.bioworld.com/articles/718122-ono-scoops-ionis-hematology-candidate-sapablursen-for-up-to-940m">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="AI drug developer Insilico sees advantages to China market " class="url" rel="" target="" href="https://www.bioworld.com/articles/718194-ai-drug-developer-insilico-sees-advantages-to-china-market"><img width="650" height="488" alt="Alex Zhavoronkov, founder and CEO, Insilico Medicine" title="Alex Zhavoronkov, founder and CEO, Insilico Medicine" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BW-source/2025/Alex-Zhavoronkov-founder-and-CEO-Insilico-Medicine-3-6.jpg?height=488&t=1741296582&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/718194-ai-drug-developer-insilico-sees-advantages-to-china-market">AI drug developer Insilico sees advantages to China market </a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 11, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">Insilico Medicine founder and CEO Alex Zhavoronkov told <em>BioWorld</em> that he tries to spend as much time as possible in China, because that's where the artificial intelligence (AI) drug development company conducts synthesis and tests for early stage discovery. “And nowadays, not a day goes by without somebody launching an AI drug discovery company,” he said, noting that Chinese AI company Deepseek could be a huge disrupter.<br /></div><a title="AI drug developer Insilico sees advantages to China market " class="more" href="https://www.bioworld.com/articles/718194-ai-drug-developer-insilico-sees-advantages-to-china-market">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Kyowa Kirin, Amgen’s rocatinlimab ignites positive response in Rocket study" class="url" rel="" target="" href="https://www.bioworld.com/articles/718110-kyowa-kirin-amgens-rocatinlimab-ignites-positive-response-in-rocket-study"><img width="650" height="488" alt="Skin irritation on hands" title="Skin irritation on hands" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Dermatologic/Dermatologic-atopic-dermatitis2.png?height=488&t=1588881560&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/718110-kyowa-kirin-amgens-rocatinlimab-ignites-positive-response-in-rocket-study">Kyowa Kirin, Amgen’s rocatinlimab ignites positive response in Rocket study</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 11, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">Analysts were pleasantly surprised by the positive phase III data reported for Kyowa Kirin Co. Ltd./Amgen Inc.’s rocatinlimab, a T-cell rebalancing therapy, in moderate to severe atopic dermatitis.<br /></div><a title="Kyowa Kirin, Amgen’s rocatinlimab ignites positive response in Rocket study" class="more" href="https://www.bioworld.com/articles/718110-kyowa-kirin-amgens-rocatinlimab-ignites-positive-response-in-rocket-study">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Inflammation appears to cause mutations linked to MS progression" class="url" rel="" target="" href="https://www.bioworld.com/articles/718190-inflammation-appears-to-cause-mutations-linked-to-ms-progression"><img width="650" height="488" alt="Justin Rubio working in the lab" title="Justin Rubio working in the lab" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/Florey-Inst-Justin-Rubio-hero-3-10.jpg?height=488&t=1741616070&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Inflammatory</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/718190-inflammation-appears-to-cause-mutations-linked-to-ms-progression">Inflammation appears to cause mutations linked to MS progression</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 11, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">For the first time, researchers have identified that inflammation – long associated with multiple sclerosis (MS) – appears to cause increased mutations that damage neurons linked to MS progression. Researchers at the Florey Institute and the University of Melbourne studied MS brain lesions, which are areas of past or ongoing brain inflammation that are visible as spots on MRI scans.<br /></div><a title="Inflammation appears to cause mutations linked to MS progression" class="more" href="https://www.bioworld.com/articles/718190-inflammation-appears-to-cause-mutations-linked-to-ms-progression">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Inflammation appears to cause mutations linked to MS progression" class="url" rel="" target="" href="https://www.bioworld.com/articles/718045-inflammation-appears-to-cause-mutations-linked-to-ms-progression"><img width="650" height="488" alt="Justin Rubio working in the lab" title="Justin Rubio working in the lab" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/Florey-Inst-Justin-Rubio-hero-3-10.jpg?height=488&t=1741616070&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Inflammatory</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/718045-inflammation-appears-to-cause-mutations-linked-to-ms-progression">Inflammation appears to cause mutations linked to MS progression</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 10, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">For the first time, researchers have identified that inflammation – long associated with multiple sclerosis (MS) – appears to cause increased mutations that damage neurons linked to MS progression. Researchers at the Florey Institute and the University of Melbourne studied MS brain lesions, which are areas of past or ongoing brain inflammation that are visible as spots on MRI scans.<br /></div><a title="Inflammation appears to cause mutations linked to MS progression" class="more" href="https://www.bioworld.com/articles/718045-inflammation-appears-to-cause-mutations-linked-to-ms-progression">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="EU MDR backlog could create an opportunity for Australia" class="url" rel="" target="" href="https://www.bioworld.com/articles/717744-eu-mdr-backlog-could-create-an-opportunity-for-australia"><img width="650" height="488" alt="Map of Europe, Medical Device Regulation (MDR) text" title="Map of Europe, Medical Device Regulation (MDR) text" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Regulatory/EU-Medical-Device-Regulation-MDR.png?height=488&t=1622066814&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/717744-eu-mdr-backlog-could-create-an-opportunity-for-australia">EU MDR backlog could create an opportunity for Australia</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 7, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">A slow-down in EU medical device audits due to the long-delayed transition to the EU Medical Device Regulation is leading to increased applications to Australia as small businesses bypass Europe altogether.<br /></div><a title="EU MDR backlog could create an opportunity for Australia" class="more" href="https://www.bioworld.com/articles/717744-eu-mdr-backlog-could-create-an-opportunity-for-australia">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="AI drug developer Insilico sees advantages to China market " class="url" rel="" target="" href="https://www.bioworld.com/articles/717947-ai-drug-developer-insilico-sees-advantages-to-china-market"><img width="650" height="488" alt="Alex Zhavoronkov, founder and CEO, Insilico Medicine" title="Alex Zhavoronkov, founder and CEO, Insilico Medicine" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BW-source/2025/Alex-Zhavoronkov-founder-and-CEO-Insilico-Medicine-3-6.jpg?height=488&t=1741296582&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/717947-ai-drug-developer-insilico-sees-advantages-to-china-market">AI drug developer Insilico sees advantages to China market </a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 6, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">Insilico Medicine founder and CEO Alex Zhavoronkov told <em>BioWorld</em> that he tries to spend as much time as possible in China, because that's where the artificial intelligence (AI) drug development company conducts synthesis and tests for early stage discovery. “And nowadays, not a day goes by without somebody launching an AI drug discovery company,” he said, noting that Chinese AI company Deepseek could be a huge disrupter.<br /></div><a title="AI drug developer Insilico sees advantages to China market " class="more" href="https://www.bioworld.com/articles/717947-ai-drug-developer-insilico-sees-advantages-to-china-market">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Inflammatory</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/718041-novartis-adds-kyorins-preclinical-mrgprx2-antagonist-in-777m-deal">Novartis adds Kyorin’s preclinical MRGPRX2 antagonist in $777M deal</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">March 5, 2025</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> </div> <div class="abstract article-summary__teaser">Kyorin Pharmaceutical Co. Ltd. has out-licensed its preclinical candidate, KRP-M223, and its back-up compounds to Novartis Pharma AG in a deal worth up to $777.5 million. 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