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Saturday, November 23, 2024</div><a class="site-banner__breaking-news" id="BREAKING_BIOWORLD" href="/articles/517055-try-bioworld-for-free-for-two-weeks">Breaking News: Try BioWorld for free for two weeks</a><a class="site-banner__breaking-news" id="BREAKING_BIOWORLD_MEDTECH" href="/articles/517055-try-bioworld-for-free-for-two-weeks">Breaking News: Try BioWorld for free for two weeks</a><a class="site-banner__breaking-news" id="BREAKING_BIOWORLD_ASIA" href="/articles/714414-duchembio-files-for-ipo-to-grow-radiopharma-business">Breaking News: Duchembio files for IPO to grow radiopharma business</a></section><section class="featured-stories__wrapper -primary-5 --secondary-3"><div class="featured-stories__primary "><section class="featured-stories "> <div class="featured-stories__items-wrapper"><ul class="featured-stories__items featured-stories__items-1"> <li class="featured-stories__item"> <article class="featured-stories__article -has-image featured-stories--article"><figure class="featured-stories__image"><a class="featured-stories__thumbnail-link" data-eventname="featured-stories" data-eventcategory="click" data-eventaction="featured-stories-image" data-eventlabel="https://www.bioworld.com/articles/714648-zai-lab-pfizer-team-up-to-widen-china-access-to-antibacterial-xacduro" href="https://www.bioworld.com/articles/714648-zai-lab-pfizer-team-up-to-widen-china-access-to-antibacterial-xacduro"><img class="featured-stories__image-thumb" alt="China U.S. deal" title="China U.S. handshake" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Geographic-regions/Asia/china-us-deal.png?height=355&t=1591119558&width=640" /></a></figure><div class="featured-stories__details featured-stories__details-1"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714648-zai-lab-pfizer-team-up-to-widen-china-access-to-antibacterial-xacduro">Zai Lab, Pfizer team up to widen China access to antibacterial Xacduro</a></h1><div class="featured-stories__teaser">Zai Lab and Pfizer Inc. are teaming up in China to fight the deadly carbapenem-resistant <em>Acinetobacter baumannii</em> (CRAB) infection with novel antibacterial drug Xacduro (sulbactam-durlobactam). Through the collaboration, Zai Lab will leverage Pfizer’s commercial infrastructure in the anti-infective space to widen access to Xacduro in mainland China. Terms of the deal were not released.</div></div></article> </li> </ul><ul class="featured-stories__items featured-stories__items-2"> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714649-celltrion-wins-korea-approvals-of-prolia-xgeva-biosimilars">Celltrion wins Korea approvals of Prolia, Xgeva biosimilars</a></h1></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article -has-image featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714650-former-fda-chief-hamburg-notes-challenging-times-post-trump-win">Former FDA chief Hamburg notes ‘challenging’ times post-Trump win</a></h1></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714651-two-stelara-biosimilars-among-15-us-fda-approvals-in-october">Two Stelara biosimilars among 15 US FDA approvals in October</a></h1></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/432891-todays-news-in-brief">Today's news in brief</a></h1></article> </li> </ul></div> </section></div><div class="featured-stories__secondary"><section class="featured-stories "> <ul class="featured-stories__items"> <li class="featured-stories__item"> <article class="featured-stories__article -has-image featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714648-zai-lab-pfizer-team-up-to-widen-china-access-to-antibacterial-xacduro">Zai Lab, Pfizer team up to widen China access to antibacterial Xacduro</a></h1><div class="featured-stories__teaser">Zai Lab and Pfizer Inc. are teaming up in China to fight the deadly carbapenem-resistant <em>Acinetobacter baumannii</em> (CRAB) infection with novel antibacterial drug Xacduro (sulbactam-durlobactam). Through the collaboration, Zai Lab will leverage Pfizer’s commercial infrastructure in the anti-infective space to widen access to Xacduro in mainland China. Terms of the deal were not released.</div></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714649-celltrion-wins-korea-approvals-of-prolia-xgeva-biosimilars">Celltrion wins Korea approvals of Prolia, Xgeva biosimilars</a></h1><div class="featured-stories__teaser">The Ministry of Food and Drug Safety (MFDS) approved South Korea’s first denosumab (Prolia/Xgeva) biosimilars, developed by Celltrion Inc. under the brand names of Stoboclo/Osenvelt (CT-P41) for respective indications, a move the company hopes will help secure first-mover advantage for the drugs, currently under review in the U.S. and Europe.</div></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article -has-image featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714650-former-fda-chief-hamburg-notes-challenging-times-post-trump-win">Former FDA chief Hamburg notes ‘challenging’ times post-Trump win</a></h1><div class="featured-stories__teaser">Former U.S. FDA Commissioner Margaret Hamburg has added her voice to concerns that the incoming Trump administration’s pledge to slim down federal agencies will damage public health. “These are certainly challenging times,” Hamburg told delegates at the World Science Forum, Budapest, Hungary, meeting to discuss issues dominating the interface between science and policy.</div></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714651-two-stelara-biosimilars-among-15-us-fda-approvals-in-october">Two Stelara biosimilars among 15 US FDA approvals in October</a></h1><div class="featured-stories__teaser">The U.S. FDA approved 15 drugs in October, marking a decline from 24 in September and 22 in August. Despite the drop, the 2024 monthly average stands at about 19 approvals, exceeding last year’s average of 16, 2022’s 12.5, and the 17-per-month averages recorded in both 2021 and 2020.</div></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/432891-todays-news-in-brief">Today's news in brief</a></h1><div class="featured-stories__teaser"><em>BioWorld</em> briefs for Nov. 22, 2024.</div></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article -has-image featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714819-machine-learning-links-microbiome-composition-to-bacterial-load">Machine learning links microbiome composition to bacterial load</a></h1><div class="featured-stories__teaser">Many studies have linked the presence of specific bacteria to various diseases. But a general overgrowth of gut bacteria can be a symptom of different conditions, including colorectal cancer and inflammatory bowel disease. </div></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714815">Healing the health divide: BioWorld reports on women’s health space</a></h1><div class="featured-stories__teaser">It’s difficult to fathom that the health of half the world’s population is underserved. But it’s a hard truth. Women’s health has traditionally focused on what Seema Kumar, the CEO of Cure, coined as the “bikini zone.” However, reproduction and breast health are a drop in the bucket when it comes to women’s health. In this multipart, in-depth series, BioWorld provides insight into the oft-overlooked space of women’s health, exposing the disparities in research and funding while looking toward future opportunities for bridging the gender gap in health care.</div></article> </li> <li class="featured-stories__item"> <article class="featured-stories__article featured-stories--article"><h1 class="featured-stories__headline"><a class="featured-stories__article-title-link" href="https://www.bioworld.com/articles/714818-bioworld-insider-podcast-healing-the-health-divide-for-women">BioWorld Insider Podcast: Healing the health divide for women</a></h1><div class="featured-stories__teaser">As a new <em>BioWorld</em> <a href="https://www.bioworld.com/womens_health">investigative report shows</a>, decades of research excluding women from clinical trials and investment decisions made in male-dominated boardrooms have led to half the world’s health needs being underserved. Karen Carey, <em>BioWorld</em>’s managing editor and chief analyst, and the managing editor of <em>Bioworld Science</em>, Anette Breindl, join <a href="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/53-healing-the-health-divide-for-women" id>this episode of the BioWorld Insider podcast</a> to talk about the business and the science of women’s health.</div></article> </li> </ul> </section></div><div class="news-service"><div class="news-service__infogram"><script id="infogram_0_9f60a7ee-b5b2-468b-9e55-86c37545565f" title="BW Financings bar graphs 10 years TH" src="https://e.infogram.com/js/dist/embed.js?3Ij" type="text/javascript"></script></div></div></section><div class="topic-podcast"><div> <a href="https://clarivate.com/life-sciences-healthcare/bioworld/order/" target="_blank"><img src="https://www.bioworld.com/ext/resources/Ads/2024/Focus-25-EOY-offer2.jpg"></a></div><section class="bioworld-podcasts-component"><div class="bioworld-podcasts-component__wrapper"><div class="bioworld-podcasts-component__content"><h3 class="bioworld-podcasts-component__headline"><a class="bioworld-podcasts-component__headline-link" href="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/53-healing-the-health-divide-for-women">BioWorld Insider Podcast</a></h3><div class="bioworld-podcasts-component__body"><img src="https://www.bioworld.com/ext/resources/Podcast-files/play-circle-button.png?1718131949" style="display: inline-block; vertical-align: bottom; margin: 5px 0px 5px 5px; text-align: right; float: right; max-width: calc(100% - 5px); width: 95px;" alt="Play button" data-uuid="YTAtMTE1OTM1" align="right">Karen Carey, <em>BioWorld</em>’s managing editor and chief analyst, and the managing editor of <em>Bioworld Science</em>, Anette Breindl, join this episode of the <em>BioWorld Insider</em> podcast to talk about the business and the science of women’s health.</div><a class="bioworld-podcasts-component__link" href="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/53-healing-the-health-divide-for-women">Listen now</a></div></div></section></div><section class="topics-section__wrapper"><div class="topics-section__primary"><section class="topics-section "> <h1 class="topics-section__title"><a class="topics-section__title-link" data-eventname="topics-section" data-eventcategory="click" data-eventaction="topics-section-title" data-eventlabel="/articles/topic/109-analysis-and-data-insight" href="/articles/topic/109-analysis-and-data-insight">Analysis and data insight</a></h1><ul class="topics-section__items"> <li class="topics-section__item"> <article class="topics-section__article topics-section--article"><div class="topics-section__details topics-section__details-1"><h1 class="topics-section__headline"><a class="topics-section__article-title-link" href="https://www.bioworld.com/articles/714628-drug-developer-stocks-slide-further-in-fall-despite-gains-from-exelixis-and-xencor">Drug developer stocks slide further in fall, despite gains from Exelixis and Xencor</a></h1><div class="topics-section__teaser">The BioWorld Drug Developers Index (BDDI) continued its downward spiral through the fall, going from a modest 1.11% decline at the end of August to a 6.2% dip in September and an 11.3% loss by October’s close. </div></div></article> </li> <li class="topics-section__item"> <article class="topics-section__article -has-image topics-section--article"><figure class="topics-section__image"><a class="topics-section__thumbnail-link" data-eventname="topics-section" data-eventcategory="click" data-eventaction="topics-section-image" data-eventlabel="https://www.bioworld.com/articles/714625-kura-kyowa-kirin-to-co-develop-ziftomenib-in-149b-deal" href="https://www.bioworld.com/articles/714625-kura-kyowa-kirin-to-co-develop-ziftomenib-in-149b-deal"><img class="topics-section__image-thumb" alt="Global handshake silhouette" title="Global handshake silhouette" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Deals-and-MAs/Global-handshake-silhouette.png?height=355&t=1670353285&width=640" /></a></figure><div class="topics-section__details topics-section__details-1"><h1 class="topics-section__headline"><a class="topics-section__article-title-link" href="https://www.bioworld.com/articles/714625-kura-kyowa-kirin-to-co-develop-ziftomenib-in-149b-deal">Kura, Kyowa Kirin to co-develop ziftomenib in $1.49B deal</a></h1><div class="topics-section__topics"><a class="topics-section__topic-link" href="/articles/topic/214,84">Deals and M&A</a></div><div class="topics-section__teaser">Kura Oncology Inc. and Kyowa Kirin Co. 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Women have smaller hearts and narrower blood vessels than men and their cardiovascular systems respond to disease and treatment...</div></div></article> </li> <li class="topics-section__item"> <article class="topics-section__article -has-image topics-section--article"><figure class="topics-section__image"><a class="topics-section__thumbnail-link" data-eventname="topics-section" data-eventcategory="click" data-eventaction="topics-section-image" data-eventlabel="https://www.bioworld.com/articles/714613-holistic-strategies-needed-to-diagnose-and-treat-endometriosis" href="https://www.bioworld.com/articles/714613-holistic-strategies-needed-to-diagnose-and-treat-endometriosis"><img class="topics-section__image-thumb" alt="Woman holding stomach with inflammation" title="Woman holding stomach with inflammation" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Inflammatory/Woman-holding-stomach-with-inflammation.jpg?height=355&t=1732047546&width=640" /></a></figure><div class="topics-section__details topics-section__details-1"><h1 class="topics-section__headline"><a class="topics-section__article-title-link" href="https://www.bioworld.com/articles/714613-holistic-strategies-needed-to-diagnose-and-treat-endometriosis">Holistic strategies needed to diagnose and treat endometriosis</a></h1><div class="topics-section__topics"><a class="topics-section__topic-link" href="/articles/topic/110,84">Science</a></div><div class="topics-section__teaser">Endometriosis has been woefully under-recognized in the medical community, and consequently, the delay between onset and diagnosis is often quite long, with some women waiting up to 12 years for a diagnosis.</div></div></article> </li> </ul><a class="topics-section__more-link" data-eventname="topics-section" data-eventcategory="click" data-eventaction="topics-section-more-link" data-eventlabel="/articles/topic/109-analysis-and-data-insight" href="/articles/topic/109-analysis-and-data-insight">More in Analysis and data insight</a> </section></div><div class="topics-section__aside"><section class="news-in-brief "> <h1 class="news-in-brief__title">Today's news in brief</h1><ul class="news-in-brief__items"> <li class="news-in-brief__item"> <article class="news-in-brief__article news-in-brief--article"><h1 class="news-in-brief__headline"><a class="news-in-brief__article-title-link" href="https://www.bioworld.com/articles/714656-appointments-and-advancements-for-nov-22-2024">Appointments and advancements for Nov. 22, 2024</a></h1></article> </li> <li class="news-in-brief__item"> <article class="news-in-brief__article news-in-brief--article"><h1 class="news-in-brief__headline"><a class="news-in-brief__article-title-link" href="https://www.bioworld.com/articles/714657-financings-for-nov-22-2024">Financings for Nov. 22, 2024</a></h1></article> </li> <li class="news-in-brief__item"> <article class="news-in-brief__article news-in-brief--article"><h1 class="news-in-brief__headline"><a class="news-in-brief__article-title-link" href="https://www.bioworld.com/articles/714658-in-the-clinic-for-nov-22-2024">In the clinic for Nov. 22, 2024</a></h1></article> </li> <li class="news-in-brief__item"> <article class="news-in-brief__article news-in-brief--article"><h1 class="news-in-brief__headline"><a class="news-in-brief__article-title-link" href="https://www.bioworld.com/articles/714659-other-news-to-note-for-nov-22-2024">Other news to note for Nov. 22, 2024</a></h1></article> </li> <li class="news-in-brief__item"> <article class="news-in-brief__article news-in-brief--article"><h1 class="news-in-brief__headline"><a class="news-in-brief__article-title-link" href="https://www.bioworld.com/articles/714660-regulatory-actions-for-nov-22-2024">Regulatory actions for Nov. 22, 2024</a></h1></article> </li> </ul> </section></div></section><section class="topics-section-2__wrapper"><div class="topics-section-2__aside"><section class="asia-pacific "> <h1 class="asia-pacific__title"><a class="asia-pacific__title-link" data-eventname="asia-pacific" data-eventcategory="click" data-eventaction="asia-pacific-title" data-eventlabel="/articles/topic/214-deals-and-m-a" href="/articles/topic/214-deals-and-m-a">Deals and M&A</a></h1><ul class="asia-pacific__items"> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714624-novartis-acquires-gene-therapy-developer-kate-therapeutics-for-11b">Novartis acquires gene therapy developer Kate Therapeutics for $1.1B</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article -has-image asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714723-radiopharma-telix-acquires-fap-targeting-agents-for-bladder-cancer">Radiopharma Telix acquires FAP-targeting agents for bladder cancer </a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714590-novartis-continues-push-into-radiopharma-with-745m-ratio-deal">Novartis continues push into radiopharma with $745M Ratio deal</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article -has-image asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714589-biosion-sells-antibody-rights-to-aclaris-in-940m-deal">Biosion sells antibody rights to Aclaris in $940M deal</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714586-keymed-platina-sign-626m-deal-for-bispecific-antibody-cm-336">Keymed, Platina sign $626M deal for bispecific antibody CM-336</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article -has-image asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714583-biopharma-deal-value-down-for-year-surges-72-in-october">Biopharma deal value, down for year, surges 72% in October</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article -has-image asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714563-vitalli-terminates-477m-daewoong-deal-retains-941m-option">Vitalli terminates $477M Daewoong deal, retains $941M option</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714562-merck-licenses-lanovas-pd-1-vegf-bispecific-in-27b-deal">Merck licenses Lanova’s PD-1/VEGF bispecific in $2.7B+ deal</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714558-celltrion-to-acquire-iqone-healthcare-switzerland-for-30b">Celltrion to acquire Iqone Healthcare Switzerland for ₩30B</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article -has-image asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714535-womens-health-by-the-data">Women's health by the data</a></h1></article> </li> </ul> </section></div><div class="topics-section-2__row"><div class="topics-section-2__col -one"><section class="bioworld-biome "> <h1 class="bioworld-biome__title"><a class="bioworld-biome__title-link" data-eventname="bioworld-biome" data-eventcategory="click" data-eventaction="bioworld-biome-title" data-eventlabel="/articles/topic/292-financings" href="/articles/topic/292-financings">Financings</a></h1><div class="bioworld-biome__items-wrapper"><ul class="bioworld-biome__items bioworld-biome__items-1"> <li class="bioworld-biome__item"> <article class="bioworld-biome__article -has-image bioworld-biome--article"><figure class="bioworld-biome__image"><a class="bioworld-biome__thumbnail-link" data-eventname="bioworld-biome" data-eventcategory="click" data-eventaction="bioworld-biome-image" data-eventlabel="https://www.bioworld.com/articles/714622-freya-adds-118m-for-microbial-immunotherapies-in-womens-health" href="https://www.bioworld.com/articles/714622-freya-adds-118m-for-microbial-immunotherapies-in-womens-health"><img class="bioworld-biome__image-thumb" alt="Fallopian tubes, ovaries and uterus" title="Fallopian tubes, ovaries and uterus" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Sexual-health/women-gyno-uterus-ovary.png?height=355&t=1589293258&width=640" /></a></figure><div class="bioworld-biome__details bioworld-biome__details-1"><h1 class="bioworld-biome__headline"><a class="bioworld-biome__article-title-link" href="https://www.bioworld.com/articles/714622-freya-adds-118m-for-microbial-immunotherapies-in-womens-health">Freya adds $11.8M for microbial immunotherapies in women’s health</a></h1><div class="bioworld-biome__topics"><a class="bioworld-biome__topic-link" href="/articles/topic/391,84">Newco news</a></div><div class="bioworld-biome__teaser">Vaginal microbiome specialist Freya Bioscience ApS has added $11.8 million to its series A, bringing the total for the round to $50 million. Of the additional $11.8 million, $10.4 million comes from the Gates Foundation and is designated for the development of vaginal microbiome-based...</div></div></article> </li> </ul><ul class="bioworld-biome__items bioworld-biome__items-2"> <li class="bioworld-biome__item"> <article class="bioworld-biome__article -has-image bioworld-biome--article"><h1 class="bioworld-biome__headline"><a class="bioworld-biome__article-title-link" href="https://www.bioworld.com/articles/714551-vcs-emerge-for-womens-health-and-its-groundbreaking-research">VCs emerge for women’s health and its ‘groundbreaking’ research</a></h1><div class="bioworld-biome__topics"><a class="bioworld-biome__topic-link" href="/articles/topic/109,84">Analysis and data insight</a></div></article> </li> <li class="bioworld-biome__item"> <article class="bioworld-biome__article -has-image bioworld-biome--article"><h1 class="bioworld-biome__headline"><a class="bioworld-biome__article-title-link" href="https://www.bioworld.com/articles/714515-despite-womens-health-inroads-lackluster-funding-impedes-progress">Despite women’s health inroads, lackluster funding impedes progress</a></h1><div class="bioworld-biome__topics"><a class="bioworld-biome__topic-link" href="/articles/topic/109,84">Analysis and data insight</a></div></article> </li> <li class="bioworld-biome__item"> <article class="bioworld-biome__article -has-image bioworld-biome--article"><h1 class="bioworld-biome__headline"><a class="bioworld-biome__article-title-link" href="https://www.bioworld.com/articles/714428-healing-a-health-divide-thats-long-overdue">Healing a health divide (that’s long overdue)</a></h1><div class="bioworld-biome__topics"><a class="bioworld-biome__topic-link" href="/articles/topic/109,84">Analysis and data insight</a></div></article> </li> <li class="bioworld-biome__item"> <article class="bioworld-biome__article -has-image bioworld-biome--article"><h1 class="bioworld-biome__headline"><a class="bioworld-biome__article-title-link" href="https://www.bioworld.com/articles/714427-alentis-adds-181m-in-series-d-for-claudin-1-focused-adc-trials">Alentis adds $181M in series D for Claudin-1-focused ADC trials</a></h1><div class="bioworld-biome__topics"><a class="bioworld-biome__topic-link" href="/articles/topic/239,84">Cancer</a></div></article> </li> </ul></div><a class="bioworld-biome__more-link" data-eventname="bioworld-biome" data-eventcategory="click" data-eventaction="bioworld-biome-more-link" data-eventlabel="/articles/topic/292-financings" href="/articles/topic/292-financings">More in Financings</a> </section></div><div class="advertisement topics-section-2__col -two"><a href="https://clarivate.com/contact-us/sales-enquiries/" target="_blank"><img src="https://www.bioworld.com/ext/resources/Ads/2024/bioworld-advertising-reach.jpg" style="width: 300px; height: 250px;"></a></div></div><div class="topics-section-2__row"><div class="topics-section-2__col -three"><section class="clinical "> <h1 class="clinical__title"><a class="clinical__title-link" data-eventname="clinical" data-eventcategory="click" data-eventaction="clinical-title" data-eventlabel="/articles/topic/110-science" href="/articles/topic/110-science">Science</a></h1><div class="clinical__items-wrapper"><ul class="clinical__items clinical__items-1"> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><figure class="clinical__image"><a class="clinical__thumbnail-link" data-eventname="clinical" data-eventcategory="click" data-eventaction="clinical-image" data-eventlabel="https://www.bioworld.com/articles/714679-more-than-100m-cells-included-in-the-human-cell-atlas" href="https://www.bioworld.com/articles/714679-more-than-100m-cells-included-in-the-human-cell-atlas"><img class="clinical__image-thumb" alt="D-rendered image showing atlas of human embryonic skeletal development" title="D-rendered image showing atlas of human embryonic skeletal development" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/Embryonic-skeletal-development-hero-11-21.jpg?height=355&t=1732207101&width=640" /></a></figure><div class="clinical__details clinical__details-1"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714679-more-than-100m-cells-included-in-the-human-cell-atlas">More than 100M cells included in the human cell atlas</a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/111,84">Artificial intelligence</a></div><div class="clinical__teaser">An international consortium of thousands of scientists is creating the Human Cell Atlas, a three-dimensional map of all the cells in the body. The goal is to understand all the cells that make up human tissues, organs and systems, which will enable multiple medical applications. This collection of...</div></div></article> </li> </ul><ul class="clinical__items clinical__items-2"> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714429-the-science-of-gender-based-medicine-many-reasons-many-manifestations">The science of gender-based medicine: many reasons, many manifestations</a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/109,84">Analysis and data insight</a></div><div class="clinical__teaser">At the BioFuture 2024 conference held in New York in November, Seema Kumar, the CEO of Cure, described women’s health as something that has been directed at the “bikini area.” That “bikini” bias extended to both diseases and their causes – women’s health covered the breasts and reproductive system,...</div></article> </li> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714462-quiescent-but-not-quiet-cancer-stem-cells-in-glioblastoma-relapse">Quiescent, but not quiet, cancer stem cells in glioblastoma relapse</a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/136,84">Stem cells</a></div><div class="clinical__teaser">Six main cell types form glioblastomas, the most aggressive brain cancer due to its high rate of recurrence. Of these six, quiescent cancer stem cells are responsible for resistance to therapy and the reappearance of the tumor, according to a study that identified the six groups and highlighted the...</div></article> </li> </ul><ul class="clinical__items clinical__items-3"> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714423-extrachromosomal-dna-acts-as-joker-for-cancer-cells">Extrachromosomal DNA acts as joker for cancer cells </a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/117,84">Drug resistance</a></div></article> </li> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714228-less-microglia-activity-may-improve-apoe4s-effect-in-alzheimers">Less microglia activity may improve APOE4’s effect in Alzheimer’s</a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/256,84">Neurology/psychiatric</a></div></article> </li> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714198-blocking-cgrp-in-endometriosis-two-birds-with-one-stone">Blocking CGRP in endometriosis: two birds with one stone?</a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/246,84">Endocrine/metabolic</a></div></article> </li> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714086-gene-editing-is-trojan-horse-of-cancer-immunotherapy">Gene editing is Trojan horse of cancer immunotherapy</a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/154,84">Conferences</a></div></article> </li> </ul></div><a class="clinical__more-link" data-eventname="clinical" data-eventcategory="click" data-eventaction="clinical-more-link" data-eventlabel="/articles/topic/110-science" href="/articles/topic/110-science">More in Science</a> </section></div></div></section><div class="deals-m-a__wrapper"><section class="deals-m-a "> <h1 class="deals-m-a__title"><a class="deals-m-a__title-link" data-eventname="deals-m-a" data-eventcategory="click" data-eventaction="deals-m-a-title" data-eventlabel="/articles/topic/391-newco-news" href="/articles/topic/391-newco-news">Newco news</a></h1><ul class="deals-m-a__items"> <li class="deals-m-a__item"> <article class="deals-m-a__article -has-image deals-m-a--article"><figure class="deals-m-a__image"><a class="deals-m-a__thumbnail-link" data-eventname="deals-m-a" data-eventcategory="click" data-eventaction="deals-m-a-image" data-eventlabel="https://www.bioworld.com/articles/714377-next-generation-gene-pioneers-gene-therapy-approach-with-china-data" href="https://www.bioworld.com/articles/714377-next-generation-gene-pioneers-gene-therapy-approach-with-china-data"><img class="deals-m-a__image-thumb" alt="Lixin Jiang, co-founder and CEO, Next Generation Gene Therapeutics Inc." title="Lixin Jiang, co-founder and CEO, Next Generation Gene Therapeutics Inc." width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/BW-source/2024/Lixin-Jiang-CEO-NGGT-11-11.jpg?height=355&t=1731360234&width=640" /></a></figure><div class="deals-m-a__details deals-m-a__details-1"><h1 class="deals-m-a__headline"><a class="deals-m-a__article-title-link" href="https://www.bioworld.com/articles/714377-next-generation-gene-pioneers-gene-therapy-approach-with-china-data">Next Generation Gene pioneers gene therapy approach with China data</a></h1><div class="deals-m-a__topics"><a class="deals-m-a__topic-link" href="/articles/topic/153,84">Clinical</a></div><div class="deals-m-a__teaser">Gene therapy faces complexities in delivering treatments due to persistent safety concerns and daunting immune responses, but Next Generation Gene Therapeutics Inc. has found a way around this issue using dual-functional vectors to simultaneously remove harmful, mutated genes and replace them with...</div></div></article> </li> <li class="deals-m-a__item"> <article class="deals-m-a__article -has-image deals-m-a--article"><figure class="deals-m-a__image"><a class="deals-m-a__thumbnail-link" data-eventname="deals-m-a" data-eventcategory="click" data-eventaction="deals-m-a-image" data-eventlabel="https://www.bioworld.com/articles/713868-hope-for-endometriosis-as-hmi-115-reduces-pelvic-pain-by-50" href="https://www.bioworld.com/articles/713868-hope-for-endometriosis-as-hmi-115-reduces-pelvic-pain-by-50"><img class="deals-m-a__image-thumb" alt="Person holding stomach in pain " title="Person holding stomach in pain " width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Gastrointestinal/Stomach-pain.png?height=355&t=1655847596&width=640" /></a></figure><div class="deals-m-a__details deals-m-a__details-1"><h1 class="deals-m-a__headline"><a class="deals-m-a__article-title-link" href="https://www.bioworld.com/articles/713868-hope-for-endometriosis-as-hmi-115-reduces-pelvic-pain-by-50">Hope for endometriosis as HMI-115 reduces pelvic pain by 50% </a></h1><div class="deals-m-a__topics"><a class="deals-m-a__topic-link" href="/articles/topic/153,84">Clinical</a></div><div class="deals-m-a__teaser">Hope Medicine Inc. reported positive interim results for monoclonal antibody HMI-115 in a phase II endometriosis trial that saw the mean non-menstrual pelvic pain score reduced by 50%. “HMI-115 is a prolactin receptor blocker, and we're using it to treat endometriosis and some other diseases. It is...</div></div></article> </li> <li class="deals-m-a__item"> <article class="deals-m-a__article -has-image deals-m-a--article"><figure class="deals-m-a__image"><a class="deals-m-a__thumbnail-link" data-eventname="deals-m-a" data-eventcategory="click" data-eventaction="deals-m-a-image" data-eventlabel="https://www.bioworld.com/articles/713687-seaport-sailing-to-the-clinic-with-a-225m-series-b" href="https://www.bioworld.com/articles/713687-seaport-sailing-to-the-clinic-with-a-225m-series-b"><img class="deals-m-a__image-thumb" alt="Gold dollar sign and blue circular arrows" title="Gold dollar sign and blue circular arrows" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Money/Gold-dollar-sign-and-blue-circular-arrows.jpg?height=355&t=1729544931&width=640" /></a></figure><div class="deals-m-a__details deals-m-a__details-1"><h1 class="deals-m-a__headline"><a class="deals-m-a__article-title-link" href="https://www.bioworld.com/articles/713687-seaport-sailing-to-the-clinic-with-a-225m-series-b">Seaport sailing to the clinic with a $225M series B</a></h1><div class="deals-m-a__topics"><a class="deals-m-a__topic-link" href="/articles/topic/292,84">Financings</a></div><div class="deals-m-a__teaser">Seaport Therapeutics Inc. has followed up its recent fundraiser with an oversubscribed $225 million series B financing that will help set it on the path to a phase IIb study in major depressive disorder. The company’s lead candidate is allopregnanolone, an endogenous neurosteroid that is taken...</div></div></article> </li> <li class="deals-m-a__item"> <article class="deals-m-a__article -has-image deals-m-a--article"><figure class="deals-m-a__image"><a class="deals-m-a__thumbnail-link" data-eventname="deals-m-a" data-eventcategory="click" data-eventaction="deals-m-a-image" data-eventlabel="https://www.bioworld.com/articles/713452-alnylams-founder-brings-in-a-135m-series-a-for-city-therapeutics" href="https://www.bioworld.com/articles/713452-alnylams-founder-brings-in-a-135m-series-a-for-city-therapeutics"><img class="deals-m-a__image-thumb" alt="John Maraganore, co-founder and executive chair, City Therapeutics" title="John Maraganore, co-founder and executive chair, City Therapeutics" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/BW-source/2024/John-Maraganore-co-founder-and-executive-chair-City-Therapeutics-10-11.jpg?height=355&t=1728674927&width=640" /></a></figure><div class="deals-m-a__details deals-m-a__details-1"><h1 class="deals-m-a__headline"><a class="deals-m-a__article-title-link" href="https://www.bioworld.com/articles/713452-alnylams-founder-brings-in-a-135m-series-a-for-city-therapeutics">Alnylam’s founder brings in a $135M series A for City Therapeutics</a></h1><div class="deals-m-a__topics"><a class="deals-m-a__topic-link" href="/articles/topic/292,84">Financings</a></div><div class="deals-m-a__teaser">The founding CEO of Alnylam Pharmaceuticals Inc. is now leading the charge with newly launched City Therapeutics Inc., which just completed a $135 million series A financing. City’s executive chair, John Maraganore, will be in familiar territory as the new company plans to develop RNAi-based...</div></div></article> </li> <li class="deals-m-a__item"> <article class="deals-m-a__article -has-image deals-m-a--article"><figure class="deals-m-a__image"><a class="deals-m-a__thumbnail-link" data-eventname="deals-m-a" data-eventcategory="click" data-eventaction="deals-m-a-image" data-eventlabel="https://www.bioworld.com/articles/713421-booster-launches-with-15m-new-approach-in-proteasome-activation" href="https://www.bioworld.com/articles/713421-booster-launches-with-15m-new-approach-in-proteasome-activation"><img class="deals-m-a__image-thumb" alt="Illustration of 20S proteasome activation" title="Illustration of 20S proteasome activation" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/BW-source/2024/Booster-Therapeutics-20S-proteasome-activation-10-10.jpg?height=355&t=1728593874&width=640" /></a></figure><div class="deals-m-a__details deals-m-a__details-1"><h1 class="deals-m-a__headline"><a class="deals-m-a__article-title-link" href="https://www.bioworld.com/articles/713421-booster-launches-with-15m-new-approach-in-proteasome-activation">Booster launches with $15M, new approach in proteasome activation</a></h1><div class="deals-m-a__topics"><a class="deals-m-a__topic-link" href="/articles/topic/292,84">Financings</a></div><div class="deals-m-a__teaser">Booster Therapeutics is ready to open up a new arm of the proteasome after raising $15 million in seed funding to advance small molecules it says can degrade multiple types of harmful proteins. Rather than tagging single disease proteins with a ubiquitin marker for degrading via 26S proteasomes,...</div></div></article> </li> </ul><a class="deals-m-a__more-link" data-eventname="deals-m-a" data-eventcategory="click" data-eventaction="deals-m-a-more-link" data-eventlabel="/articles/topic/391-newco-news" href="/articles/topic/391-newco-news">More in Newco news</a> </section></div><section class="topics-section-2__wrapper"><div class="topics-section-2__aside"><section class="asia-pacific "> <h1 class="asia-pacific__title"><a class="asia-pacific__title-link" data-eventname="asia-pacific" data-eventcategory="click" data-eventaction="asia-pacific-title" data-eventlabel="/articles/topic/402-regulatory" href="/articles/topic/402-regulatory">Regulatory</a></h1><ul class="asia-pacific__items"> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" 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offering: Syndax wins Revuforj FDA nod in KM2A leukemia</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article -has-image asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714561-trumps-hhs-pick-kennedy-set-to-go-wild-on-health">Trump’s HHS pick Kennedy set to ‘go wild on health’?</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714560-eisai-wins-on-appeal-chmp-recommends-leqembi-for-alzheimers">Eisai wins on appeal: CHMP recommends Leqembi for Alzheimer’s</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article -has-image asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714514-prv-sweetens-ptc-approval-of-kebilidi-in-aadc-deficiency">PRV sweetens PTC approval of Kebilidi in AADC deficiency</a></h1></article> </li> <li class="asia-pacific__item"> <article class="asia-pacific__article asia-pacific--article"><h1 class="asia-pacific__headline"><a class="asia-pacific__article-title-link" href="https://www.bioworld.com/articles/714458-daiichi-sankyo-astrazeneca-submit-new-bla-for-trop2-lung-cancer-adc">Daiichi Sankyo, Astrazeneca submit new BLA for Trop2 lung cancer ADC</a></h1></article> </li> </ul> </section></div><div class="topics-section-2__row"><div class="topics-section-2__col -one"><section class="bioworld-biome "> <h1 class="bioworld-biome__title"><a class="bioworld-biome__title-link" data-eventname="bioworld-biome" data-eventcategory="click" data-eventaction="bioworld-biome-title" data-eventlabel="/articles/topic/401-u-s" href="/articles/topic/401-u-s">U.S.</a></h1><div 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href="https://www.bioworld.com/articles/714592-neurogene-slides-on-rett-syndrome-gene-therapy-safety-concern">Neurogene slides on Rett syndrome gene therapy safety concern</a></h1><div class="bioworld-biome__topics"><a class="bioworld-biome__topic-link" href="/articles/topic/153,84">Clinical</a></div></article> </li> <li class="bioworld-biome__item"> <article class="bioworld-biome__article -has-image bioworld-biome--article"><h1 class="bioworld-biome__headline"><a class="bioworld-biome__article-title-link" href="https://www.bioworld.com/articles/714591-the-liver-meeting-a-cure-for-hepatitis-bs-low-hanging-fruit">The Liver Meeting: A cure for hepatitis B’s low-hanging fruit</a></h1><div class="bioworld-biome__topics"><a class="bioworld-biome__topic-link" href="/articles/topic/153,84">Clinical</a></div></article> </li> </ul></div><a class="bioworld-biome__more-link" data-eventname="bioworld-biome" data-eventcategory="click" data-eventaction="bioworld-biome-more-link" data-eventlabel="/articles/topic/401-u-s" href="/articles/topic/401-u-s">More in U.S.</a> </section></div><div class="advertisement topics-section-2__col -two"><a href="https://clarivate.com/contact-us/sales-enquiries/" target="_blank"><img src="https://www.bioworld.com/ext/resources/Ads/2024/bioworld-advertising-audience.jpg" style="width: 300px; height: 250px;"></a></div></div><div class="topics-section-2__row"><div class="topics-section-2__col -three"><section class="clinical "> <h1 class="clinical__title"><a class="clinical__title-link" data-eventname="clinical" data-eventcategory="click" data-eventaction="clinical-title" data-eventlabel="/articles/topic/396-europe" href="/articles/topic/396-europe">Europe</a></h1><div class="clinical__items-wrapper"><ul class="clinical__items clinical__items-1"> <li class="clinical__item"> <article class="clinical__article -has-image clinical--article"><figure class="clinical__image"><a class="clinical__thumbnail-link" data-eventname="clinical" data-eventcategory="click" data-eventaction="clinical-image" data-eventlabel="https://www.bioworld.com/articles/714724-newamsterdams-obicetrapib-combo-nails-phase-iii-ldl-c-endpoints" href="https://www.bioworld.com/articles/714724-newamsterdams-obicetrapib-combo-nails-phase-iii-ldl-c-endpoints"><img class="clinical__image-thumb" alt="Cholesterol plaque in artery" title="Cholesterol plaque in artery" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cardiovascular/Cholesterol.png?height=355&t=1667944246&width=640" /></a></figure><div class="clinical__details clinical__details-1"><h1 class="clinical__headline"><a class="clinical__article-title-link" href="https://www.bioworld.com/articles/714724-newamsterdams-obicetrapib-combo-nails-phase-iii-ldl-c-endpoints">Newamsterdam’s obicetrapib combo nails phase III LDL-C endpoints</a></h1><div class="clinical__topics"><a class="clinical__topic-link" href="/articles/topic/153,84">Clinical</a></div><div class="clinical__teaser">“It all comes down to outcomes,” said Michael Davidson, CEO of Newamsterdam Pharma Co. 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