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href="#main-content" class="visually-hidden focusable skip-link"> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div class="main-container"> <header class="page--lab page"> <div class="region__header--inner region--inner"> <section id="block-bccrc-breadcrumbs" class="block block--system-breadcrumb-block block-bccrc-breadcrumbs"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/dept/tfl/">Terry Fox Laboratory</a> </li> <li> Krystal Lab </li> </ol> </nav> </section> <section id="block-bccrc-page-title" class="block block--page-title-block block-bccrc-page-title"> <h1><span>Krystal Lab</span> </h1> </section> </div> </header> <section class="region region__highlight"> <div class="region__highlight--inner region--inner"> <div data-drupal-messages-fallback class="hidden"></div> </div> </section> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <section class="region region__content"> <div class="region__content--inner region--inner"> <section id="block-bccrc-content" class="block block--system-main-block block-bccrc-content"> <article class="node node--lab full"> <div class="node__inner"> <footer class="node"> <aside> <a href="/dept/tfl/people/gerald-gerry-krystal" class="button"><span>Gerald (Gerry) Krystal, PhD</span> </a> <div class="field field--field_phone_number"><a href="tel:604-675-8130">604-675-8130</a></div> <div class="field field--field_laboratory_contact"> <div class="above field--label">Laboratory Contact</div> <div> <div class="field field--item field--field_laboratory_contact"><article class="node node--profile assistant"> <div class="field--name"> <span>Ingrid Elisia, PhD</span> </div> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Staff Scientist</div> </div> <div class="field field--field_phone_number"><a href="tel:604-675-8000ext.7722">604-675-8000 ext. 7722</a></div> </article> </div> </div> </div> </aside> </footer> <div class="node__main"> </div> </div> </article> <section id="people" class="layout layout__grid"><h2 class="section__title">Members</h2><h3 class="subsection__title">Faculty/Leaders</h3><div class="flexgrid"><article class="node node--profile teaser"> <a class="picture" href="/dept/tfl/people/gerald-gerry-krystal" ><figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-08/Gerry%20dark%20bg1.jpg?itok=liMa9afT" width="580" height="460" alt="" /> </figure></a> <section> <h3 class="node__title"> <a href="/dept/tfl/people/gerald-gerry-krystal" rel="bookmark">Gerald (Gerry) Krystal, PhD</a> </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Distinguished Scientist</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/labs/krystal-lab" hreflang="en">Krystal Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8130">604-675-8130</a></div> <a href= "https://www.bccrc.ca/dept/tfl/contact/143" class="more">Send message</a> <a href="/dept/tfl/people/gerald-gerry-krystal" class="more" rel="bookmark">Bio <i class="fa fa-chevron-right"></i></a> </div> </section> </article> </div><h3 class="subsection__title">Staff</h3><div class="flexgrid"><article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-08/ingrid-809x1024.jpg?itok=17Sqc3uF" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Ingrid Elisia, PhD </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Staff Scientist</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/labs/krystal-lab" hreflang="en">Krystal Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000ext.7722">604-675-8000 ext. 7722</a></div> <a href= "https://www.bccrc.ca/dept/tfl/contact/141" class="more">Send message</a> </div> </section> </article> <article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-07/Yeung_Michelle.jpg?itok=gMQY2ggX" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Michelle Wing-Shue Yeung </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Research Assistant</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/labs/krystal-lab" hreflang="en">Krystal Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000Ext.7722">604-675-8000 Ext. 7722</a></div> <a href= "https://www.bccrc.ca/dept/tfl/contact/146" class="more">Send message</a> </div> </section> </article> </div><h3 class="subsection__title">Students/Trainees</h3><div class="flexgrid"><article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-05/BCPCM-portrait.png?itok=nEtgTObd" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Nicola Janz </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Coop</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/labs/krystal-lab" hreflang="en">Krystal Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000ext.7722">604-675-8000 ext. 7722</a></div> <a href= "https://www.bccrc.ca/dept/tfl/contact/877" class="more">Send message</a> </div> </section> </article> <article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-05/BCPCM-portrait.png?itok=nEtgTObd" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Michaela Schweitzer </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Coop</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/labs/krystal-lab" hreflang="en">Krystal Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000ext.7722">604-675-8000 ext. 7722</a></div> <a href= "https://www.bccrc.ca/dept/tfl/contact/878" class="more">Send message</a> </div> </section> </article> <article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-05/BCPCM-portrait.png?itok=nEtgTObd" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Ka Wing (Amy) Wong </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Honour Thesis</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/labs/krystal-lab" hreflang="en">Krystal Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000Ext.7722">604-675-8000 Ext. 7722</a></div> <a href= "https://www.bccrc.ca/dept/tfl/contact/735" class="more">Send message</a> </div> </section> </article> <article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-05/BCPCM-portrait.png?itok=nEtgTObd" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Samantha Wu </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Honour Thesis</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/labs/krystal-lab" hreflang="en">Krystal Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000ext.7722">604-675-8000 ext. 7722</a></div> <a href= "https://www.bccrc.ca/dept/tfl/contact/888" class="more">Send message</a> </div> </section> </article> </div></section> <section id="publications" class="layout layout__expanding layout__publications"><h2 class="section__title">Selected Publications</h2><button class="icon" data-expand></button><div class="field field--field_text"> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/33173057" target="_blank" rel="bookmark">The effect of smoking on chronic inflammation, immune function and blood cell composition.</a> </h2> <div class="field field--field_journal">Scientific reports, 2020</div> <div class="field field--field_authors">Elisia, Ingrid, Lam, Vivian, Cho, Brandon, Hay, Mariah, Li, Michael Yu, Yeung, Michelle, Bu, Luke, Jia, William, Norton, Nancy, Lam, Stephen, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/33173057" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/32215551" target="_blank" rel="bookmark">Low carbohydrate diets containing soy protein and fish oil slow the growth of established NNK-induced lung tumors.</a> </h2> <div class="field field--field_journal">Carcinogenesis, 2020</div> <div class="field field--field_authors">Elisia, Ingrid, Hay, Mariah, Cho, Brandon, Yeung, Michelle, Kowalski, Sara, Wong, Jennifer, Lam, Vivian, Larsen, Meegan, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/32215551" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/32823063" target="_blank" rel="bookmark">Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-inflammatory Effects through SHIP1/STAT3 Complexes.</a> </h2> <div class="field field--field_journal">iScience, 2020</div> <div class="field field--field_authors">Chamberlain, Thomas C, Cheung, Sylvia T, Yoon, Jeff S J, Ming-Lum, Andrew, Gardill, Bernd R, Shakibakho, Soroush, Dzananovic, Edis, Ban, Fuqiang, Samiea, Abrar, Jawanda, Kamaldeep, Priatel, John, Krystal, Gerald, Ong, Christopher J, Cherkasov, Artem, Andersen, Raymond J, McKenna, Sean A, Van Petegem, Filip, Mui, Alice L-F</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/32823063" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/32027700" target="_blank" rel="bookmark">Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk.</a> </h2> <div class="field field--field_journal">PloS one, 2020</div> <div class="field field--field_authors">Elisia, Ingrid, Lam, Vivian, Cho, Brandon, Hay, Mariah, Li, Michael Yu, Kapeluto, Jordanna, Elliott, Tom, Harris, David, Bu, Luke, Jia, William, Leung, Hilary, Mohn, William, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/32027700" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/30933043" target="_blank" rel="bookmark">UV Light-inactivated HSV-1 Stimulates Natural Killer Cell-induced Killing of Prostate Cancer Cells.</a> </h2> <div class="field field--field_journal">Journal of immunotherapy (Hagerstown, Md. : 1997), 2019</div> <div class="field field--field_authors">Samudio, Ismael, Hofs, Elyse, Cho, Brandon, Li, Michael, Bolduc, Kayla, Bu, Luke, Liu, Guoyu, Lam, Vivian, Rennie, Paul, Jia, William, Elisia, Ingrid, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/30933043" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/30874285" target="_blank" rel="bookmark">The effect of diet and exercise on tobacco carcinogen-induced lung cancer.</a> </h2> <div class="field field--field_journal">Carcinogenesis, 2019</div> <div class="field field--field_authors">Elisia, Ingrid, Cho, Brandon, Hay, Mariah, Li, Michael Yu, Hofs, Elyse, Lam, Vivian, Dyer, Roger A, Lum, Julian, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/30874285" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29186188" target="_blank" rel="bookmark">Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges.</a> </h2> <div class="field field--field_journal">PloS one, 2017</div> <div class="field field--field_authors">Elisia, Ingrid, Lam, Vivian, Hofs, Elyse, Li, Michael Yu, Hay, Mariah, Cho, Brandon, Brooks-Wilson, Angela, Rosin, Miriam, Bu, Luke, Jia, William, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/29186188" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/26941401" target="_blank" rel="bookmark">UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells.</a> </h2> <div class="field field--field_journal">Blood, 2016</div> <div class="field field--field_authors">Samudio, Ismael, Rezvani, Katayoun, Shaim, Hila, Hofs, Elyse, Ngom, Mor, Bu, Luke, Liu, Guoyu, Lee, Jason T C, Imren, Suzan, Lam, Vivian, Poon, Grace F T, Ghaedi, Maryam, Takei, Fumio, Humphries, Keith, Jia, William, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/26941401" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/27977740" target="_blank" rel="bookmark">All Trans Retinoic Acid, Transforming Growth Factor 尾 and Prostaglandin E2 in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages.</a> </h2> <div class="field field--field_journal">PloS one, 2016</div> <div class="field field--field_authors">Ho, Victor W, Hofs, Elyse, Elisia, Ingrid, Lam, Vivian, Hsu, Brian E, Lai, June, Luk, Beryl, Samudio, Ismael, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/27977740" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/26683227" target="_blank" rel="bookmark">SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice.</a> </h2> <div class="field field--field_journal">Oncotarget, 2016</div> <div class="field field--field_authors">Hamilton, Melisa J, Halvorsen, Elizabeth C, LePard, Nancy E, Bosiljcic, Momir, Ho, Victor W, Lam, Vivian, Ban谩th, Judit, Bennewith, Kevin L, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/26683227" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/25797030" target="_blank" rel="bookmark">A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice.</a> </h2> <div class="field field--field_journal">The Journal of steroid biochemistry and molecular biology, 2015</div> <div class="field field--field_authors">Fokidis, H Bobby, Yieng Chin, Mei, Ho, Victor W, Adomat, Hans H, Soma, Kiran K, Fazli, Ladan, Nip, Ka Mun, Cox, Michael, Krystal, Gerald, Zoubeidi, Amina, Tomlinson Guns, Emma S</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/25797030" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/25023988" target="_blank" rel="bookmark">A low carbohydrate, high protein diet combined with celecoxib markedly reduces metastasis.</a> </h2> <div class="field field--field_journal">Carcinogenesis, 2014</div> <div class="field field--field_authors">Ho, Victor W, Hamilton, Melisa J, Dang, Ngoc-Ha Thi, Hsu, Brian E, Adomat, Hans H, Guns, Emma S, Weljie, Aalim, Samudio, Ismael, Bennewith, Kevin L, Krystal, Gerald</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/25023988" target="_blank">Learn More</a></div> </article> <article class="node publication teaser"> <h2 class="node__title"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/21673053" target="_blank" rel="bookmark">A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation.</a> </h2> <div class="field field--field_journal">Cancer research, 2011</div> <div class="field field--field_authors">Ho, Victor W, Leung, Kelvin, Hsu, Anderson, Luk, Beryl, Lai, June, Shen, Sung Yuan, Minchinton, Andrew I, Waterhouse, Dawn, Bally, Marcel B, Lin, Wendy, Nelson, Brad H, Sly, Laura M, Krystal, Gerald</div> <div 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