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</span>Find a Clinical Trial</a> </li> </ul> </nav> <section class="views-element-container block block--views-blockcarousel-block-1 block-views-block-carousel-block-1" id="block-views-block-carousel-block-1"> <div><div class="js-view-dom-id-d14925a8a36bda15166a66abf27546601f29e18d83b2882c95ae6705c69d9a72 view view--carousel"> <div class="views-row"><div class="views-field views-field-field-carousel"><div class="field-content"><div class="field field--carousel carousel" data-timeout="5000" data-slides=".layout__carousel_slide"> <section class="layout layout__carousel_slide layout__parent__node carousel__slide_49 tinted" id="paragraph--49"> <div class="inner"> <h2 class="section__title">Experimental Therapeutics</h2> <div class="field field--summary"> <p><strong>Experimental Therapeutics is a translational research department which provides therapeutic and diagnostic development capabilities focused on the critical need to rapidly establish the therapeutic value of emerging technologies through validated assessments in preclinical models of cancer and in patients.</strong></p> </div> </div> </section> <section class="layout layout__carousel_slide layout__parent__node carousel__slide_77 tinted" id="paragraph--77"> <div class="inner"> <h2 class="section__title">Investigational Drug Program</h2> </div> </section> <section class="layout layout__carousel_slide layout__parent__node carousel__slide_78 tinted" id="paragraph--78"> <div class="inner"> <h2 class="section__title">Pancreas Centre BC</h2> </div> </section> </div> </div></div></div> </div> </div> </section> </div> </header> <section class="region region__highlight"> <div class="region__highlight--inner region--inner"> <div data-drupal-messages-fallback class="hidden"></div> </div> </section> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <section class="region region__content"> <div class="region__content--inner region--inner"> <section id="block-bccrc-content" class="block block--system-main-block block-bccrc-content"> <article class="node node--front full"> <div class="field field--body"><h2>Defining better intervention strategies for individuals diagnosed with aggressive cancers.</h2></div> </article> <section class="layout layout__callout layout__parent__node has-background paragraph paragraph--type--callout paragraph--view-mode--default" id="our-focus"> <div class="section__title"><h2 class="section__title">Our Focus</h2></div> <div class="inner"> <div class="background"> </div> <div class="field field--summary"> <h3>A translational research department providing therapeutic and diagnostic development capabilities focused on the evaluation and application of emerging technologies in cancer care.</h3> <p>By conducting research to obtain a better understanding of disease classification and targeted therapies, Experimental Therapeutics (ET) endeavors to define better intervention strategies for individuals with aggressive cancers. ET is well respected internationally for its track record of proficiency and efficiency when linking preclinical and clinical research, and is focused on the critical need to rapidly establish the therapeutic value of emerging technologies through validated assessments in preclinical models of cancer and in patients.</p> </div> </div> </section> <section class="layout layout__callout layout__parent__node has-background paragraph paragraph--type--callout paragraph--view-mode--default" id="what-we-do"> <div class="section__title"><h2 class="section__title">What We Do</h2></div> <div class="inner"> <div class="background"> </div> <div class="field field--summary"> <p>Experimental Therapeutics has a variety of drug development capabilities, including preclinical models (cell-based and animal-model based models) and formal capabilities to support some GLP studies (Rodent GLP) and GMP manufacturing. Our research ranges from development of nanomedicines to identification of unique, targetable, proteins in cells. </p> </div> </div> </section> <section class="layout layout__news layout__parent__node paragraph paragraph--type--news paragraph--view-mode--default" id="paragraph--108"> <h2 class="section__title">News & Events</h2><div class="inner"><div class="featured"><article class="node--article teaser"> <a href="/dept/et/news/pancreatic-cancer-patients-health-improves-after-receiving-personalized-treatment" class="image"><figure class="remote-image"><img src="//www.bccrc.ca/sites/bccrc.ca/files/styles/large/public/2019-10/Pancreas.jpg?itok=p15aPGQc" alt=""></figure></a> <div class="node__inner"> <footer class="node"> <article> </article> <div> <span><time datetime="2019-05-15T13:15:27-07:00" title="Wednesday, May 15, 2019 - 1:15pm">May 15, 2019</time> </span> </div> </footer> <h2 class="node__title"><a href="/dept/et/news/pancreatic-cancer-patients-health-improves-after-receiving-personalized-treatment" rel="bookmark"><span>Pancreatic cancer patient’s health improves after receiving personalized treatment</span> </a></h2> <div class="field field--body">Thanks in part to genetic sequencing and BC Cancer researchers; one BC man has a new lease on life.</div> <ul class="links inline"><li class="node-readmore"><a href="/dept/et/news/pancreatic-cancer-patients-health-improves-after-receiving-personalized-treatment" rel="tag" title="Pancreatic cancer patient’s health improves after receiving personalized treatment" hreflang="en">More Info<span class="visually-hidden"> about Pancreatic cancer patient’s health improves after receiving personalized treatment</span></a></li></ul> </div> </article> </div></div> </section> </section> <section class="views-element-container block block--views-blocklabs-block-1 block--research-labs-amp-principal-investigators block-views-block-labs-block-1" id="block-views-block-labs-block-1"> <h2 class="section__title">Research Labs & Principal Investigators</h2> <div><div class="js-view-dom-id-496670137ae86a1a5050624a4754a6fa57943fe2147ea7555760f0a58a30377a view view--labs"> <div class="views-view-grid view--labs cols-4"> <article class="node lab teaser"> <a href="/dept/et/labs/bally-lab"><figure> <img loading="lazy" src="/dept/et/sites/experimentaltherapeutics/files/styles/profile/public/2019-10/Marcel%20Bally05bw.jpg?itok=JZikjU7p" width="580" height="460" alt="" /> </figure> </a> <h2 class="node__title"> <a href="/dept/et/labs/bally-lab" rel="bookmark" ><span>Bally Lab</span> </a> </h2> </article> <article class="node lab teaser"> <a href="/dept/et/labs/wang-lab"><figure> <img loading="lazy" src="/dept/et/sites/experimentaltherapeutics/files/styles/profile/public/2019-10/DSC07340.jpg?itok=t9YCsKco" width="580" height="460" alt="" /> </figure> </a> <h2 class="node__title"> <a href="/dept/et/labs/wang-lab" rel="bookmark" ><span>Wang Lab</span> </a> </h2> </article> </div> </div> </div> </section> <section class="views-element-container block block--views-blockpublications-block-1 block--recent-publications block-views-block-publications-block-1" id="block-views-block-publications-block-1"> <h2 class="section__title">Recent Publications</h2> <div><div class="js-view-dom-id-a0b112685cbf5fb2a48d5f4ed3a949cb82f77bd3c29775fbb288611db3b6df0d view view--publications"> <div class="views-view-grid view--publications cols-3"> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/37075872" target="_blank" rel="bookmark">Malignant function of nuclear factor-kappaB axis in prostate cancer: Molecular interactions and regulation by non-coding RNAs.</a></p> <div class="field field--field_journal">Pharmacological research, 2023</div> <div class="field field--field_authors">Al-Rashidi, Reyadh R, Noraldeen, Sara Abdalrazzaq M, Kareem, Ali Kamil, Mahmoud, Aisha Kamal, Kadhum, Wesam R, Ramírez-Coronel, Andrés Alexis, Iswanto, Acim Heri, Obaid, Rasha Fadhel, Jalil, Abduladheem Turki, Mustafa, Yasser Fakri, Nabavi, Noushin, Wang, Yuzhuo, Wang, Lin</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/37075872" target="_blank">Learn More</a></div> </article> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/37556934" target="_blank" rel="bookmark">Establishment and validation of preclinical models of SMARCA4-inactivated and ARID1A/ARID1B co-inactivated dedifferentiated endometrial carcinoma.</a></p> <div class="field field--field_journal">Gynecologic oncology, 2023</div> <div class="field field--field_authors">Wong, Nelson K Y, Llaurado Fernandez, Marta, Kommoss, Felix K F, Praveen Kumar, Pooja, Kim, Hannah, Liu, Jiahui, Zhang, Guihua, Coatham, Mackenzie, Lin, Yen-Yi, Haegert, Anne M, Volik, Stanislav, Le Bihan, Stephane, Collins, Colin C, Fu, Yangxin, Postovit, Lynne M, von Deimling, Andreas, Wu, Rebecca, Xue, Hui, Wang, Yuzhuo, Köbel, Martin, Carey, Mark S, Lee, Cheng-Han</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/37556934" target="_blank">Learn More</a></div> </article> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/37347559" target="_blank" rel="bookmark">Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth.</a></p> <div class="field field--field_journal">The Journal of clinical investigation, 2023</div> <div class="field field--field_authors">Gritsina, Galina, Fong, Ka-Wing, Lu, Xiaodong, Lin, Zhuoyuan, Xie, Wanqing, Agarwal, Shivani, Lin, Dong, Schiltz, Gary E, Beltran, Himisha, Corey, Eva, Morrissey, Colm, Wang, Yuzhuo, Zhao, Jonathan C, Hussain, Maha, Yu, Jindan</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/37347559" target="_blank">Learn More</a></div> </article> </div> <nav role="navigation" 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