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</span>Find a Clinical Trial</a> </li> </ul> </nav> <section class="views-element-container block block--views-blockcarousel-block-1 block-views-block-carousel-block-1" id="block-views-block-carousel-block-1"> <div><div class="js-view-dom-id-5f5b2a3ec5e1d2a228b9735921ece6da54c99953fff1bf5bc13e9d425e92cd43 view view--carousel"> <div class="views-row"><div class="views-field views-field-field-carousel"><div class="field-content"><div class="field field--carousel carousel" data-timeout="5000" data-slides=".layout__carousel_slide"> <section class="layout layout__carousel_slide layout__parent__node carousel__slide_49 tinted" id="paragraph--49"> <div class="inner"> <h2 class="section__title">Experimental Therapeutics</h2> <div class="field field--summary"> <p><strong>Experimental Therapeutics is a translational research department which provides therapeutic and diagnostic development capabilities focused on the critical need to rapidly establish the therapeutic value of emerging technologies through validated assessments in preclinical models of cancer and in patients.</strong></p> </div> </div> </section> <section class="layout layout__carousel_slide layout__parent__node carousel__slide_77 tinted" id="paragraph--77"> <div class="inner"> <h2 class="section__title">Investigational Drug Program</h2> </div> </section> <section class="layout layout__carousel_slide layout__parent__node carousel__slide_78 tinted" id="paragraph--78"> <div class="inner"> <h2 class="section__title">Pancreas Centre BC</h2> </div> </section> </div> </div></div></div> </div> </div> </section> </div> </header> <section class="region region__highlight"> <div class="region__highlight--inner region--inner"> <div data-drupal-messages-fallback class="hidden"></div> </div> </section> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <section class="region region__content"> <div class="region__content--inner region--inner"> <section id="block-bccrc-content" class="block block--system-main-block block-bccrc-content"> <article class="node node--front full"> <div class="field field--body"><h2>Defining better intervention strategies for individuals diagnosed with aggressive cancers.</h2></div> </article> <section class="layout layout__callout layout__parent__node has-background paragraph paragraph--type--callout paragraph--view-mode--default" id="our-focus"> <div class="section__title"><h2 class="section__title">Our Focus</h2></div> <div class="inner"> <div class="background"> </div> <div class="field field--summary"> <h3>A translational research department providing therapeutic and diagnostic development capabilities focused on the evaluation and application of emerging technologies in cancer care.</h3> <p>By conducting research to obtain a better understanding of disease classification and targeted therapies, Experimental Therapeutics (ET) endeavors to define better intervention strategies for individuals with aggressive cancers. ET is well respected internationally for its track record of proficiency and efficiency when linking preclinical and clinical research, and is focused on the critical need to rapidly establish the therapeutic value of emerging technologies through validated assessments in preclinical models of cancer and in patients.</p> </div> </div> </section> <section class="layout layout__callout layout__parent__node has-background paragraph paragraph--type--callout paragraph--view-mode--default" id="what-we-do"> <div class="section__title"><h2 class="section__title">What We Do</h2></div> <div class="inner"> <div class="background"> </div> <div class="field field--summary"> <p>Experimental Therapeutics has a variety of drug development capabilities, including preclinical models (cell-based and animal-model based models) and formal capabilities to support some GLP studies (Rodent GLP) and GMP manufacturing. Our research ranges from development of nanomedicines to identification of unique, targetable, proteins in cells. </p> </div> </div> </section> <section class="layout layout__news layout__parent__node paragraph paragraph--type--news paragraph--view-mode--default" id="paragraph--108"> <h2 class="section__title">News & Events</h2><div class="inner"><div class="featured"><article class="node--article teaser"> <a href="/dept/et/dept/et/news/pancreatic-cancer-patients-health-improves-after-receiving-personalized-treatment" class="image"><figure class="remote-image"><img src="//www.bccrc.ca/sites/bccrc.ca/files/styles/large/public/2019-10/Pancreas.jpg?itok=p15aPGQc" alt=""></figure></a> <div class="node__inner"> <footer class="node"> <article> </article> <div> <span><time datetime="2019-05-15T13:15:27-07:00" title="Wednesday, May 15, 2019 - 1:15pm">May 15, 2019</time> </span> </div> </footer> <h2 class="node__title"><a href="/dept/et/dept/et/news/pancreatic-cancer-patients-health-improves-after-receiving-personalized-treatment" rel="bookmark"><span>Pancreatic cancer patient’s health improves after receiving personalized treatment</span> </a></h2> <div class="field field--body">Thanks in part to genetic sequencing and BC Cancer researchers; one BC man has a new lease on life.</div> <ul class="links inline"><li class="node-readmore"><a href="/dept/et/dept/et/news/pancreatic-cancer-patients-health-improves-after-receiving-personalized-treatment" rel="tag" title="Pancreatic cancer patient’s health improves after receiving personalized treatment" hreflang="en">More Info<span class="visually-hidden"> about Pancreatic cancer patient’s health improves after receiving personalized treatment</span></a></li></ul> </div> </article> </div></div> </section> </section> <section class="views-element-container block block--views-blocklabs-block-1 block--research-labs-amp-principal-investigators block-views-block-labs-block-1" id="block-views-block-labs-block-1"> <h2 class="section__title">Research Labs & Principal Investigators</h2> <div><div class="js-view-dom-id-551782b811e19aef682c1e17dd53431ea2dc1599d2e323a7ccdeb8666d3bd06e view view--labs"> <div class="views-view-grid view--labs cols-4"> <article class="node lab teaser"> <a href="/dept/et/dept/et/labs/bally-lab"><figure> <img loading="lazy" src="/dept/et/sites/experimentaltherapeutics/files/styles/profile/public/2019-10/Marcel%20Bally05bw.jpg?itok=JZikjU7p" width="580" height="460" alt="" /> </figure> </a> <h2 class="node__title"> <a href="/dept/et/dept/et/labs/bally-lab" rel="bookmark" ><span>Bally Lab</span> </a> </h2> </article> <article class="node lab teaser"> <a href="/dept/et/dept/et/labs/wang-lab"><figure> <img loading="lazy" src="/dept/et/sites/experimentaltherapeutics/files/styles/profile/public/2019-10/DSC07340.jpg?itok=t9YCsKco" width="580" height="460" alt="" /> </figure> </a> <h2 class="node__title"> <a href="/dept/et/dept/et/labs/wang-lab" rel="bookmark" ><span>Wang Lab</span> </a> </h2> </article> </div> </div> </div> </section> <section class="views-element-container block block--views-blockpublications-block-1 block--recent-publications block-views-block-publications-block-1" id="block-views-block-publications-block-1"> <h2 class="section__title">Recent Publications</h2> <div><div class="js-view-dom-id-9e00a449a274366f08dc6b07eb2289c4ac97963dc2569f027df3707af992e238 view view--publications"> <div class="views-view-grid view--publications cols-3"> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/39776163" target="_blank" rel="bookmark"><span>Exploring B7-H4's role in prostate cancer dormancy post-androgen deprivation therapy: extracellular matrix interactions and therapeutic opportunities.</span> </a></p> <div class="field field--field_journal">Mol Cancer Res, 2025 </div> <div class="field field--field_authors">Kang N, Xue H, Wong NKY, Lin YY, Classen A, Wu R, Oo HZ, Dong X, Trinh A, Lin D, Daugaard M, Ong C, Collins C, Gleave M, Wang Y.</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/39776163" target="_blank">Learn More</a></div> </article> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/39878501" target="_blank" rel="bookmark"><span>EZH2 inhibition enhances the activity of Carboplatin in aggressive-variant prostate cancer cell lines.</span> </a></p> <div class="field field--field_journal">Epigenomics, 2025</div> <div class="field field--field_authors">Latarani M, Pucci P, Eccleston M, Manzo M, Gangadharannambiar P, Fischetti I, Alborelli I, Mongiardini V, Mahmood N, Colombo MP, Grimaldi B, Rigas S, Akamatsu S, Hawkes C, Wang Y, Jachetti E, Crea F</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/39878501" target="_blank">Learn More</a></div> </article> <article> <p class="node__title"><a href="https://www.ncbi.nlm.nih.gov/pubmed/38961395" target="_blank" rel="bookmark"><span>Accumulation of liposomes in metastatic tumor sites is not necessary for anti-cancer drug efficacy.</span> </a></p> <div class="field field--field_journal">J Transl Med, 2024</div> <div class="field field--field_authors">Kalra J, Baker J, Sun X, Kyle A, Minchinton A, Bally MB</div> <div class="field field--field_pubmed_id"><a href="https://www.ncbi.nlm.nih.gov/pubmed/38961395" target="_blank">Learn More</a></div> </article> </div> <nav role="navigation" aria-labelledby="pagination-heading"> <h4 class="visually-hidden">Pagination</h4> <ul class="js-pager__items pager__items mini"> <li> <a href="/dept/et/experimental-therapeutics?page=1" title="Go to next page" rel="next"> <span class="visually-hidden">Next page</span> <span aria-hidden="true">››</span> </a> </li> </ul> </nav> </div> </div> </section> </div> </section> </div> <a class="top" href="#main-content">Back to top</a> </main> <section class="region region__cta"> <div class="region__cta--inner region--inner"> <section id="block-sitecalltoaction" class="block block--block-contenta8a59224-4648-42d5-b71c-294b3c630d8a block-sitecalltoaction"> <div class="field field--body"><p>BC Cancer Foundation is the fundraising partner of BC Cancer, which includes BC Cancer Research. Together with our donors, we are changing cancer outcomes for British Columbians by funding innovative research and personalized treatment and care.</p> <p><a class="button" href="https://bccancerfoundation.com/donations/general-donation-form/?s_src=BCCRCFooter" target="_blank">Donate Today</a></p></div> </section> </div> </section> <footer class="page" role="contentinfo"> <section class="region region__footer"> <div class="region__footer--inner region--inner"> <section id="block-bccrc-branding" class="block block--system-branding-block block-bccrc-branding"> <a href="/dept/et/" title="Home" rel="home"> <img src="/dept/et/sites/experimentaltherapeutics/files/BCClogo_Research_ExperimentalTherapeutics_RGB.png" alt="Home" /> </a> </section> <section id="block-contactus" class="block block--block-content2314a90f-9af6-4a1e-8cf5-6a294688e075 block--contact-us block-contactus"> <h2 class="section__title">Contact Us</h2> <div class="field field--body"><p>BC Cancer Research Institute<br> 675 West 10th Avenue<br> Vancouver, BC V5Z 1L3</p> <p>604 675 8000</p> <p>Toll Free: 1 888 675 8001</p></div> </section> <section id="block-followus" class="block block--block-content06fb6d8a-948b-4134-bf4f-c16a4f797215 block--follow-us block-followus"> <h2 class="section__title">Follow Us</h2> <div class="field field--body"><p><a class="fa fa-linkedin" href="https://www.linkedin.com/company/bc-cancer/"> </a><a class="fa fa-twitter" href="https://twitter.com/BCCancer"> </a><a class="fa fa-instagram" href="https://www.instagram.com/bccancer/"> </a></p></div> </section> <section id="block-phsa" class="block block--block-content288c07b1-9e42-46f4-a804-fdd18540fbad block-phsa"> <div class="field field--body"><p><a href="http://www.phsa" target="_blank"><img alt="PHSA" src="https://www.bccrc.ca/dept/et/sites/experimentaltherapeutics/files/PHSA-logo.svg"></a></p></div> </section> </div> </section> </footer> <section class="region region__copyright"> <div class="region__copyright--inner region--inner"> <nav role="navigation" aria-labelledby="block-bccrc-footer-menu" id="block-bccrc-footer"> <h2 class="visually-hidden" id="block-bccrc-footer-menu">Footer menu</h2> <ul class="menu"> <li class="menu-item"> <a href="http://www.phsa.ca/privacy">Privacy Policy</a> </li> <li>Copyright © BC Cancer. 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