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data-nav="trigger" data-nav-search data-nav-target="nav-search" href="/search.aspx"><span class="a11y-sr-only">Search</span></a> <div class="nav__primary__dropdown" data-nav="target" id="nav-search"> <p data-module="label-float"> <label for="site-search"> <span class="nav-search__label--desktop">What are you searching for?</span> <span class="nav-search__label--mobile">Search</span> </label> <input type="search" id="site-search" value=""> <button class="fat-button"><span class="a11y-sr-only">Submit</span></button> </p> </div> </li> </ul> </nav> </header>    <main class="site-main" id="main-content" tabindex="-1"> <div id="panelMainContent"> <section class="layout-columns"> <div class="layout-columns__sidebar -padding--horizontal -padding--vertical -background--blue"> <div class="layout-columns__sidebar__content"> <h1 class="sidebar-heading"> <span class="sidebar-heading__subheading">Topic</span>Obesity </h1> </div> </div> <div class="layout-columns__main -padding--vertical -padding--horizontal"> <div class="layout-columns__main__content"> <ul class="content-tease__list"> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/digestive-health/journal.aspx?id=1236" itemprop="url"> Medication Confers Additional Weight Loss After Bariatric Surgery in Young Adults</a> </h3> <p itemprop="description"> <p>Three medications often prescribed by obesity medicine physicians are effective for young adults who have inadequate weight loss or regain weight after bariatric surgery.</p></p> <p class="content-tease__related"> <a href="/digestive-health/specialty.aspx?id=1007" itemprop="relatedLink">Digestive Health</a>, <a href="/digestive-health/topic.aspx?id=1039" itemprop="relatedLink">Obesity</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2019-03-27" itemprop="datePublished">March 27, 2019</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/digestive-health/journal.aspx?id=1240" itemprop="url"> Obesity Tied to Risk of Diverticulosis</a> </h3> <p itemprop="description"> <p>By analyzing a cohort of adults who underwent colonoscopy, gastroenterologists at Massachusetts General Hospital have determined that overweight and obesity substantially increase the risk of diverticulosis.</p></p> <p class="content-tease__related"> <a href="/digestive-health/topic.aspx?id=1040" itemprop="relatedLink">Bowel Disease</a>, <a href="/digestive-health/specialty.aspx?id=1007" itemprop="relatedLink">Digestive Health</a>, <a href="/digestive-health/topic.aspx?id=1039" itemprop="relatedLink">Obesity</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2019-03-29" itemprop="datePublished">March 29, 2019</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/digestive-health/journal.aspx?id=1237" itemprop="url"> BMI Linked to Diverticulitis in Women</a> </h3> <p itemprop="description"> <p>Using data from the Nurses' Health Study, gastroenterologists at Massachusetts General Hospital found an independent association between BMI and risk of diverticulitis in women.</p></p> <p class="content-tease__related"> <a href="/digestive-health/topic.aspx?id=1040" itemprop="relatedLink">Bowel Disease</a>, <a href="/digestive-health/specialty.aspx?id=1007" itemprop="relatedLink">Digestive Health</a>, <a href="/digestive-health/topic.aspx?id=1104" itemprop="relatedLink">Diverticulitis</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2019-03-20" itemprop="datePublished">March 20, 2019</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/endocrinology/journal.aspx?id=2576" itemprop="url"> In Utero Exposure to SARS-CoV-2 May Increase the Risk of Cardiometabolic Disease</a> </h3> <p itemprop="description"> <p><span>Massachusetts General Hospital researchers found that infants who have in utero exposure to maternal SARS-CoV-2 exhibit lower birth weight followed by accelerated weight gain in the first year of life, a pattern thought to increase the risk of obesity and cardiometabolic disease in childhood and adulthood.</span></p></p> <p class="content-tease__related"> <a href="/research-and-innovation/topic.aspx?id=1056" itemprop="relatedLink">COVID-19</a>, <a href="/endocrinology/specialty.aspx?id=1015" itemprop="relatedLink">Endocrinology</a>, <a href="/obgyn/specialty.aspx?id=1006" itemprop="relatedLink">OB/GYN</a>, <a href="/digestive-health/topic.aspx?id=1039" itemprop="relatedLink">Obesity</a>, <a href="/obgyn/topic.aspx?id=1034" itemprop="relatedLink">Obstetrics</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-01-23" itemprop="datePublished">January 23, 2024</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/obgyn/journal.aspx?id=2564" itemprop="url"> Sex-specific Impact of Maternal Obesity on Fetal Placental Macrophages and Cord Blood Triglycerides</a> </h3> <p itemprop="description"> <p>Lydia<span>L. Shook, MD, Andrea G. Edlow, MD, MSc, and colleagues observed that maternal obesity was more immune-activating in the male than female placenta. They also observed sexual dimorphism in placental lipid transfer. These findings may explain sex differences in cardiometabolic disease risk in obesity-exposed offspring.</span></p></p> <p class="content-tease__related"> <a href="/obgyn/specialty.aspx?id=1006" itemprop="relatedLink">OB/GYN</a>, <a href="/digestive-health/topic.aspx?id=1039" itemprop="relatedLink">Obesity</a>, <a href="/obgyn/topic.aspx?id=1034" itemprop="relatedLink">Obstetrics</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2023-12-26" itemprop="datePublished">December 26, 2023</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/cardiovascular/journal.aspx?id=2503" itemprop="url"> Body Fat Distribution Affects Risk of Cardiometabolic Disease</a> </h3> <p itemprop="description"> <p><span>Based on data UK Biobank, Amit V. Khera, MD, MSc, and colleagues used a machine learning approach to measure visceral (VAT), abdominal subcutaneous (ASAT), and gluteofemoral (GFAT) adipose tissue volumes with high accuracy.</span></p></p> <p class="content-tease__related"> <a href="/cardiovascular/specialty.aspx?id=1002" itemprop="relatedLink">Cardiovascular</a>, <a href="/cardiovascular/topic.aspx?id=1002" itemprop="relatedLink">Coronary Artery Disease</a>, <a href="/endocrinology/topic.aspx?id=1105" itemprop="relatedLink">Diabetes</a>, <a href="/digestive-health/topic.aspx?id=1039" itemprop="relatedLink">Obesity</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2023-06-21" itemprop="datePublished">June 21, 2023</time> </p> </div> </li> </ui> <p class="fat-link__cta u-flush u-text-right"> <a class="fat-link -caret -large" href="https://advances.massgeneral.org/search.aspx?q=*&st=1&topic=obesity&maxResults=15">View All Obesity Updates</a> </p> </div> </div> </section> <section class="-background--grey -padding--vertical -padding--horizontal"> <div class="content-container -width--wide -centered"> <h2 class="section-heading -centered">Obesity Contributors</h2> <ul class="profile-card__list" id="profile-cards"> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="Andrew Chan, MD, MPH" itemprop="image" srcset="/assets/images/contributors/david_chan_advances.png, /assets/images/contributors/david_chan_advances_2x.png 2x" src="/assets/images/contributors/david_chan_advances.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1318" itemprop="url">Andrew T. Chan, MD, MPH</a> </h3> <p itemprop="jobTitle"> Daniel K. Podolsky Professor of Medicine, Harvard Medical School, Director for Cancer Epidemiology, Mass General Cancer Center, Chief, Clinical and Translational Epidemiology Unit, Department of Medicine</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/digestive-health/article-external.aspx?id=1169">Taking Aspirin Associated With Reduction in Colorectal Cancer Among High-Risk Population</a> </p> </div> <p class="profile-card__image"> <img alt="Andrew Chan, MD, MPH" itemprop="image" srcset="/assets/images/contributors/david_chan_advances.png, /assets/images/contributors/david_chan_advances_2x.png 2x" src="/assets/images/contributors/david_chan_advances.png"> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/fatima_stanford_advances.png, /assets/images/contributors/fatima_stanford_advances_2x.png 2x" src="/assets/images/contributors/fatima_stanford_advances.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1316" itemprop="url">Fatima Cody Stanford, MD, MPH, MPA, MBA</a> </h3> <p itemprop="jobTitle"> Obesity Medicine Physician for Adults, Adolescents, and Children, Mass General Weight Center, Assistant Professor of Medicine, Harvard Medical School, Affiliated Faculty, MGH Mongan Institute of Health Policy and Associate, MGH Disparities Solution Center</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/digestive-health/journal.aspx?id=2059">Review: Weight Regulation in Menopause</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/fatima_stanford_advances.png, /assets/images/contributors/fatima_stanford_advances_2x.png 2x" src="/assets/images/contributors/fatima_stanford_advances.png"> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/hamed_khalili_advances.png, /assets/images/contributors/hamed_khalili_advances_2x.png 2x" src="/assets/images/contributors/hamed_khalili_advances.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1324" itemprop="url">Hamed Khalili, MD, MPH</a> </h3> <p itemprop="jobTitle"> Gastroenterologist, Clinical and Translational Epidemiology Unit, Director of Clinical Research in Inflammatory Bowel Disease in the Division of Gastroenterology, Associate Professor of Medicine, Harvard Medical School</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/digestive-health/journal.aspx?id=2316">Initiating Oral Contraception Does Not Change Gut Microbiome in Healthy Women</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/hamed_khalili_advances.png, /assets/images/contributors/hamed_khalili_advances_2x.png 2x" src="/assets/images/contributors/hamed_khalili_advances.png"> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1319" itemprop="url">Wenjie Ma, MBBS, ScD</a> </h3> <p itemprop="jobTitle"> Instructor and Investigator in the Clinical and Translational Epidemiology Unit, Assistant in Epidemiology in the Division of Gastroenterology, Instructor in Medicine, Harvard Medical School</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/digestive-health/journal.aspx?id=2282">Initiating Screening Before Age 50 Reduces Risk of Colorectal Cancer</a> </p> </div> <p class="profile-card__image"> <img alt="" itemprop="image" srcset=", 2x" src=""> </p> </li> </ul> </div> </section> <div class="content-container -width--xwide -centered specialty-block__wrapper" id="specialty-block"> <style> #specialty-block .specialty-block__image { /* 540px */ background-image: url(/assets/raw/specialty-block/subscription_callout_digestive-health_advances1x.jpg); } only screen and (-webkit-min-device-pixel-ratio: 2), only screen and (min--moz-device-pixel-ratio: 2), only screen and (-moz-min-device-pixel-ratio: 2), only screen and (-o-min-device-pixel-ratio: 2/1), only screen and (min-device-pixel-ratio: 2), only screen and (min-resolution: 192dpi), only screen and (min-resolution: 2dppx) { #specialty-block .specialty-block__image { /* 1080 width */ background-image: url(/assets/raw/specialty-block/subscription_callout_digestive-health_advances2x.jpg); } } /* </style> <span class="specialty-block__image"></span> <div class="specialty-block"> <h2 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