CINXE.COM

<!DOCTYPE html> <html dir="ltr" lang="en"> <head> <meta http-equiv="X-UA-Compatible" content="IE=Edge"> <meta charset="utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1"> <link rel="apple-touch-icon" sizes="180x180" href="/assets/images/favicons/apple-touch-icon.png"> <link rel="icon" type="image/png" href="/assets/images/favicons/favicon-32x32.png" sizes="32x32"> <link rel="icon" type="image/png" href="/assets/images/favicons/favicon-16x16.png" sizes="16x16"> <link rel="mask-icon" href="/assets/images/favicons/safari-pinned-tab.svg" color="#5bbad5"> <meta name="description" content="Advances in Motion provides Health care professionals with information about the latest breakthroughs, research and clinical advances from Mass General Hospital." > <title>Advances in Motion Massachusetts General Hospital</title> <link rel="canonical" href="https://advances.massgeneral.org"> <link href="/assets/styles/index.css" rel="stylesheet"> <link href="/assets/styles/jquery-ui-min.css" rel="stylesheet"> <link href="https://use.typekit.net/sgz4evs.css" rel="stylesheet"> <script src="/assets/scripts/jquery-3.2.1.min.js" ></script> </head> <body>  <a class="a11y-skip-link" href="#main-content">Skip to content</a>   <script type="text/javascript"> (function(window, document, dataLayerName, id) { window[dataLayerName]=window[dataLayerName]||[],window[dataLayerName].push({start:(new Date).getTime(),event:"stg.start"});var scripts=document.getElementsByTagName('script')[0],tags=document.createElement('script'); function stgCreateCookie(a,b,c){var d="";if(c){var e=new Date;e.setTime(e.getTime()+24*c*60*60*1e3),d="; expires="+e.toUTCString()}document.cookie=a+"="+b+d+"; path=/"} var isStgDebug=(window.location.href.match("stg_debug")||document.cookie.match("stg_debug"))&&!window.location.href.match("stg_disable_debug");stgCreateCookie("stg_debug",isStgDebug?1:"",isStgDebug?14:-1); var qP=[];dataLayerName!=="dataLayer"&&qP.push("data_layer_name="+dataLayerName),isStgDebug&&qP.push("stg_debug");var qPString=qP.length>0?("?"+qP.join("&")):""; tags.async=!0,tags.src="https://mgb.containers.piwik.pro/"+id+".js"+qPString,scripts.parentNode.insertBefore(tags,scripts); !function(a,n,i){a[n]=a[n]||{};for(var c=0;c<i.length;c++)!function(i){a[n][i]=a[n][i]||{},a[n][i].api=a[n][i].api||function(){var a=[].slice.call(arguments,0);"string"==typeof a[0]&&window[dataLayerName].push({event:n+"."+i+":"+a[0],parameters:[].slice.call(arguments,1)})}}(i[c])}(window,"ppms",["tm","cm"]); })(window, document, 'dataLayer', '41b8ae76-3079-47d5-aaf8-040ee367d152'); </script>  <header class="site-header" data-header="main"> <div class="site-header__nav-container"> <span class="site-header__logo"> <a href="https://www.massgeneral.org">Massachusetts General Hospital</a> </span> <div class="nav__primary__item -search mobile__search-toggle"> <button id="mobile__search-trigger" data-nav="trigger"> <span class="a11y-sr-only">Search</span> </button> </div> <button class="site-nav__toggle" aria-controls="site-navigation" aria-haspopup="true" aria-expanded="false" data-module="nav-toggle"> <span class="a11y-sr-only">Menu</span> </button> </div> <div class="site-header__sub-block" data-header="sub"> <p class="site-header__tagline"> <a href="/default.aspx">Advances in <i>Motion</i></a> </p> </div> <nav aria-label="Main navigation" class="site-nav" id="site-navigation"> <ul class="nav__utility" role="presentation"> <li><a href="/event-education-listing.aspx">Education & Training</a></li> <li><a href="/clinical-trial-listing.aspx">Clinical Trials</a></li> <li><a href="https://www.massgeneral.org/appointments-and-referrals/referral-request">Refer a Patient</a></li> <li><a href="https://www.massgeneral.org/doctors/">Find a Doctor</a></li> <li><a href="https://www.massgeneral.org/research/">Research Institute</a></li> <li><a class="nav__utility--highlight" href="https://advances.massgeneral.org/subscription.aspx">Subscribe</a></li> </ul> <ul class="nav__primary" data-module="navigation" role="presentation"> <li> <a class="nav__primary__trigger -home-link" href="/default.aspx"> <span class="nav__link-wrapper">Advances in Motion Home</span> </a> </li> <li class="nav__primary__item"> <a class="nav__primary__trigger" data-nav="trigger" data-nav-target="nav-specialties" href="/specialty-listing.aspx"> <span class="nav__link-wrapper">Specialties</span></a> <div class="nav__primary__dropdown" data-nav="target" id="nav-specialties"> <ul class="nav__primary__dropdown__links" role="presentation"> <li><a href="https://advances.massgeneral.org/cardiovascular/specialty.aspx?id=1002">Cardiovascular</a></li> <li><a href="https://advances.massgeneral.org/digestive-health/specialty.aspx?id=1007">Digestive Health</a></li> <li><a href="https://advances.massgeneral.org/endocrinology/specialty.aspx?id=1015">Endocrinology</a></li> <li><a href="https://advances.massgeneral.org/geriatrics/specialty.aspx?id=1009">Geriatrics & Palliative Care</a></li> <li><a href="https://advances.massgeneral.org/neuro/specialty.aspx?id=1004">Neuroscience</a></li> <li><a href="https://advances.massgeneral.org/obgyn/specialty.aspx?id=1006">OB/GYN</a></li> <li><a href="https://advances.massgeneral.org/oncology/specialty.aspx?id=1008">Oncology</a></li> <li><a href="https://advances.massgeneral.org/ophthalmology/specialty.aspx?id=1014">Ophthalmology</a></li> <li><a href="https://advances.massgeneral.org/ortho/specialty.aspx?id=1003">Orthopaedics</a></li> <li><a href="https://advances.massgeneral.org/otolaryngology/specialty.aspx?id=1016">Otolaryngology</a></li> <li><a href="https://advances.massgeneral.org/pulmonary/specialty.aspx?id=1012">Pulmonary & Critical Care</a></li> <li><a href="https://advances.massgeneral.org/radiology/specialty.aspx?id=1013">Radiology</a></li> <li><a href="https://advances.massgeneral.org/rheumatology/specialty.aspx?id=1010">Rheumatology, Allergy & Immunology</a></li> <li><a href="https://advances.massgeneral.org/urology/specialty.aspx?id=1005">Urology</a></li> </ul> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret" href="/specialty-listing.aspx">View All Specialties</a> </p> </div> </li> <li class="nav__primary__item"> <a class="nav__primary__trigger" data-nav="trigger" data-nav-target="nav-topics" href="/topic-listing.aspx"> <span class="nav__link-wrapper">Topics</span> </a> <div class="nav__primary__dropdown -topics" data-nav="target" id="nav-topics"> <h4>Recently Updated</h4> <div class="nav__primary__dropdown__flex-container" id="topics-scroll-container"> <section class="flex-container__section"> <ul class="flex-container__links -alt" role="presentation"> <li> <a href="/research-and-innovation/topic.aspx?id=1114" target="_blank">Gene and Cell Therapy</a><p>November 5, 2024</p> </li> <li> <a href="/otolaryngology/topic.aspx?id=1113" target="_blank">Hearing Loss</a><p>November 5, 2024</p> </li> <li> <a href="/research-and-innovation/topic.aspx?id=1107" target="_blank">Women's Health</a><p>November 5, 2024</p> </li> <li> <a href="/neuro/topic.aspx?id=1038" target="_blank">Alzheimer's Disease</a><p>October 1, 2024</p> </li> <li> <a href="/neuro/topic.aspx?id=1018" target="_blank">Neurology</a><p>October 1, 2024</p> </li> <li> <a href="/oncology/topic.aspx?id=1059" target="_blank">Colorectal Cancer</a><p>September 11, 2024</p> </li> <li> <a href="/neuro/topic.aspx?id=1031" target="_blank">Depression</a><p>September 10, 2024</p> </li> <li> <a href="/neuro/topic.aspx?id=1017" target="_blank">Psychiatry</a><p>September 10, 2024</p> </li> <li> <a href="/neuro/topic.aspx?id=1029" target="_blank">Addiction</a><p>September 4, 2024</p> </li> <li> <a href="/neuro/topic.aspx?id=1043" target="_blank">Traumatic Brain Injury</a><p>September 2, 2024</p> </li> </ul> </section> <section class="flex-container__section"> <h5>Featured</h5> <ul class="flex-container__links" role="presentation"> <li> <a href="https://advances.massgeneral.org/ortho/topic.aspx?id=1009">Sports Medicine</a> </li> <li> <a href="https://advances.massgeneral.org/research-and-innovation/topic.aspx?id=1056">COVID-19</a> </li> <li> <a href="https://advances.massgeneral.org/neuro/topic.aspx?id=1024">Neurodegenerative Disease</a> </li> <li> <a href="https://advances.massgeneral.org/pulmonary/topic.aspx?id=1058">ARDS</a> </li> <li> <a href="https://advances.massgeneral.org/research-and-innovation/topic.aspx?id=1068">Telemedicine</a> </li> </ul> </section> </div> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret" href="/topic-listing.aspx">View All Topics</a> </p> </div> </li> <li> <a class="nav__primary__trigger" href="/multimedia-listing.aspx"> <span class="nav__link-wrapper">Multimedia</span> </a> </li> <li class="nav__primary__item -search"> <a class="nav__primary__trigger" data-nav="trigger" data-nav-search data-nav-target="nav-search" href="/search.aspx"><span class="a11y-sr-only">Search</span></a> <div class="nav__primary__dropdown" data-nav="target" id="nav-search"> <p data-module="label-float"> <label for="site-search"> <span class="nav-search__label--desktop">What are you searching for?</span> <span class="nav-search__label--mobile">Search</span> </label> <input type="search" id="site-search" value=""> <button class="fat-button"><span class="a11y-sr-only">Submit</span></button> </p> </div> </li> </ul> </nav> </header>    <main class="site-main" id="main-content" tabindex="-1"> <div id="panelMainContent"> <section class="-padding--horizontal"> <div class="-width--wide -centered -padding--vertical -border--bottom--tablet-up"> <div class="content-container -width--narrow -centered"> <p class="lede u-text-centered"> Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.</p> <p class="featured-links -width--xnarrow"> <a class="featured-link" href="/specialty-listing.aspx">EXPLORE OUR SPECIALTIES</a> <i class="featured-link__separator"></i> <a class="featured-link" href="/topic-listing.aspx">BROWSE OUR TOPICS</a> <i class="featured-link__separator"></i> <a class="featured-link" href="https://pages.connect.massgeneral.org/subscription-center-med-prof.html">SUBSCRIBE TO RECEIVE UPDATES</a> </p> </div> </div> </section> <section class="-padding--horizontal -padding--vertical"> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__pod--half"> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__image"> <a href="/neuro/article.aspx?id=1570"> <img itemprop="image" srcset="/neuro/assets/neuro_homepage_restless-leg-syndrome_advances.jpg, /neuro/assets/neuro_homepage_restless-leg-syndrome_advancesx2.jpg" src="/neuro/assets/neuro_homepage_restless-leg-syndrome_advances.jpg"> </a> </p> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/neuro/specialty.aspx?id=1004">In Neuroscience</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/article.aspx?id=1570" itemprop="url">New Website Allows Provider Consultations for Patients With Restless Leg Syndrome</a> </h3> <p itemprop="description"> A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives. </p> <p class="content-tease__related"> <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-04-29" itemprop="datePublished">April 29, 2024</time> </p> </div> </div> <div class="layout-columns__pod--half"> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__image"> <a href="/otolaryngology/article.aspx?id=1574"> <img itemprop="image" srcset="/otolaryngology/assets/homepage_ent_toth-center_advances.jpg, /otolaryngology/assets/homepage_ent_toth-center_advancesx2.jpg" src="/otolaryngology/assets/homepage_ent_toth-center_advances.jpg"> </a> </p> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/otolaryngology/specialty.aspx?id=1016">In Otolaryngology</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/otolaryngology/article.aspx?id=1574" itemprop="url">The Toth Center: New Leadership, Novel Innovations</a> </h3> <p itemprop="description"> Scientists are working towards new, innovative approaches to faster and more accurate diagnoses, less invasive treatments, predictive medicine, and more. With new leadership and collaborations, the Toth Center at Mass Eye and Ear is making great headway for the future of head and neck cancer care. </p> <p class="content-tease__related"> <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-06-18" itemprop="datePublished">June 18, 2024</time> </p> </div> </div> </div> </section> <section class="-padding--horizontal -padding--vertical"> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__pod--third"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/ortho/specialty.aspx?id=1003">In Orthopaedics</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/ortho/journal.aspx?id=2628" itemprop="url">First AI Model Developed for Diagnosis of Hip Dysplasia From Plain Radiographs</a> </h3> <p itemprop="description"> <span>Martin Magnéli, MD, PhD, Orhun Muratoglu, PhD, and colleagues have developed two convolutional neural networks that can read plain radiographs and classify hips as dysplastic or non-dysplastic with 83% to 92% accuracy, and detect the severity of hip dysplasia based on the Crowe or Hartofilakidis classifications.</span> </p> <p class="content-tease__related"> <a href="/research-and-innovation/topic.aspx?id=1111" itemprop="relatedLink">Artificial Intelligence</a>, <a href="/ortho/topic.aspx?id=1007" itemprop="relatedLink">Hip and Knee</a>, <a href="/ortho/specialty.aspx?id=1003" itemprop="relatedLink">Orthopaedics</a>, <a href="/radiology/specialty.aspx?id=1013" itemprop="relatedLink">Radiology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-06-03" itemprop="datePublished">June 3, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/oncology/specialty.aspx?id=1008">In Oncology</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/oncology/article.aspx?id=1566" itemprop="url">Revolutionizing Cancer Immunotherapy for Melanoma and Beyond</a> </h3> <p itemprop="description"> Researchers at Massachusetts General Hospital won a Breakthrough Award to enhance personalized approaches to immunotherapy for metastatic melanoma. </p> <p class="content-tease__related"> <a href="/oncology/topic.aspx?id=1081" itemprop="relatedLink">Immunotherapy</a>, <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-04-09" itemprop="datePublished">April 9, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/obgyn/specialty.aspx?id=1006">In OB/GYN</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/obgyn/journal.aspx?id=2626" itemprop="url">Single-Step Blastocyst Warming Validated, Saves Time Without Compromising Outcomes</a> </h3> <p itemprop="description"> <span>Victoria S. Jiang, MD, Charles L. Bormann, PhD, and colleagues found that compared with standard blastocyst warming, a simpler protocol that removes at least 15 minutes from warming time yields similar rates of implantation, clinical pregnancy, spontaneous abortion, and live birth as well as similar birth weight.</span> </p> <p class="content-tease__related"> <a href="/obgyn/topic.aspx?id=1047" itemprop="relatedLink">Fertility</a>, <a href="/obgyn/specialty.aspx?id=1006" itemprop="relatedLink">OB/GYN</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-05-29" itemprop="datePublished">May 29, 2024</time> </p> </div> </div> </div> </section> <section class="-padding--vertical -padding--horizontal -background--grey" style="background-image: url(/assets/images/home-latest-bg.jpg);"> <div class="content-container -width--wide -centered -padding--bottom"> <h2 class="u-text-centered heading-h3">The Latest Digestive Health Advances</h2> </div> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__main"> <div class="layout-columns__main__content"> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/digestive-health/article-external.aspx?id=1169" itemprop="url"> Taking Aspirin Associated With Reduction in Colorectal Cancer Among High-Risk Population</a> </h3> <p itemprop="description"> <p>Massachusetts General Hospital researchers found that regular aspirin use was associated with the greatest reduction of colorectal cancer among those at the highest risk.</p></p> <p class="content-tease__related"> <a href="/oncology/topic.aspx?id=1059" itemprop="relatedLink">Colorectal Cancer</a>, <a href="/digestive-health/specialty.aspx?id=1007" itemprop="relatedLink">Digestive Health</a>, <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-09-11" itemprop="datePublished">September 11, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/digestive-health/journal.aspx?id=2641" itemprop="url"> Cholesterol-reducing Gut Bacteria Might Lower Heart Disease Risk</a> </h3> <p itemprop="description"> <p>Ramnik J. Xavier, MD, PhD, Chenhao Li, PhD, Martin Stražar, PhD, and colleagues have found that cholesterol metabolism is an important property of certain gut bacteria, Oscillibacter, with potential benefits for lipid homeostasis and cardiovascular health.</p></p> <p class="content-tease__related"> <a href="/cardiovascular/specialty.aspx?id=1002" itemprop="relatedLink">Cardiovascular</a>, <a href="/digestive-health/specialty.aspx?id=1007" itemprop="relatedLink">Digestive Health</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-08-05" itemprop="datePublished">August 5, 2024</time> </p> </div> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret -large" href="/digestive-health/specialty.aspx?id=1007">View all Digestive Health Updates</a> </p> </div> </div> <div class="layout-columns__sidebar"> <div class="layout-columns__sidebar__content"> <div class="profile-compact__wrapper"> <p class="u-no-margin"> <strong>Contributing Physicians</strong> </p> <div class="profile -compact" itemscope itemtype="http://schema.org/Person"> <div class="profile__content"> <h3 class="profile__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1329" itemprop="url">Ashwin N. Ananthakrishnan, MBBS, MPH</a></h3> <p class="profile__title" itemprop="jobTitle">Director of the Crohn's and Colitis Center, Division of Gastroenterology, Mass General, Associate Professor of Medicine, Harvard Medical School </p> </div> <p class="profile__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/ashwin_ananthakrishan_advances.png, /assets/images/contributors/ashwin_ananthakrishan_advances_2x.png 2x" src="/assets/images/contributors/ashwin_ananthakrishan_advances.png"> </p> </div> <div class="profile -compact" itemscope itemtype="http://schema.org/Person"> <div class="profile__content"> <h3 class="profile__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1328" itemprop="url">Ramnik Joseph Xavier, MD, PhD</a></h3> <p class="profile__title" itemprop="jobTitle">Director, Center for the Study of Inflammatory Bowel Disease, Kurt J. Isselbacher Professor of Medicine in the Field of Gastroenterology, Harvard Medical School</p> </div> <p class="profile__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/xavier_ramnik_advances.png, /assets/images/contributors/xavier_ramnik_advances_2x.png 2x" src="/assets/images/contributors/xavier_ramnik_advances.png"> </p> </div> </div> </div> </div> </div> </section> <section class="-padding--vertical -padding--horizontal"> <div class="content-container -width--wide -centered -padding--bottom -border--bottom--tablet-up"> <h2 class="section-heading -centered">Advances Specialties</h2> <div class="layout-columns -width--wide -centered" data-module="equal-heights" data-columns=".layout-columns__pod--third" data-rows=".content-tease"> <div class="layout-columns__pod--third -padding--bottom"> <h3 class="content-tease__heading -large"> <a href="/neuro/specialty.aspx?id=1004">Neuroscience</a> </h3> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/article-external.aspx?id=1170" itemprop="url"> Fish Oil May Reduce Risk of Alzheimer's Disease in High-Risk Population</a> </h3> <p itemprop="description"> <p>A study published in JAMA Network Open evaluated 102 people aged 75 and up who had lower levels of omega-3 fatty acids, a key ingredient in fish oil. Fish oil supplements are thought to improve brain function for people with memory issues.</p></p> <p class="content-tease__related"> <a href="/neuro/topic.aspx?id=1038" itemprop="relatedLink">Alzheimer's Disease</a>, <a href="/neuro/topic.aspx?id=1018" itemprop="relatedLink">Neurology</a>, <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-10-01" itemprop="datePublished">October 1, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/journal.aspx?id=2646" itemprop="url"> Propensity Score Weighting Accounts Well for Placebo Response in Two Trials of Medical Therapy for MDD</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-09-10" itemprop="datePublished">September 10, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/q-a.aspx?id=1029" itemprop="url"> Insights on Substance Use Disorder Treatment and Stigma Reduction: Q&A With Sarah Wakeman, MD</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -qa">Q & A</span> <time class="date" datetime="2024-09-04" itemprop="datePublished">September 4, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third -padding--bottom"> <h3 class="content-tease__heading -large"> <a href="/pulmonary/specialty.aspx?id=1012">Pulmonary and Critical Care</a> </h3> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/endocrinology/article-external.aspx?id=1168" itemprop="url"> Bionic Pancreas Improves Glycemic Control in Patients With Cystic Fibrosis-related Diabetes</a> </h3> <p itemprop="description"> <p>Melissa Putman, MD, Jordan Sherwood, MD, and colleagues report that the insulin-only iLet bionic pancreas improved glucose control in patients with cystic fibrosis-related diabetes (CFRD) compared to usual care, without an increase in continuous glucose monitoring-measured hypoglycemia.</p></p> <p class="content-tease__related"> <a href="/endocrinology/topic.aspx?id=1105" itemprop="relatedLink">Diabetes</a>, <a href="/endocrinology/specialty.aspx?id=1015" itemprop="relatedLink">Endocrinology</a>, <a href="/pulmonary/specialty.aspx?id=1012" itemprop="relatedLink">Pulmonary and Critical Care</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-08-14" itemprop="datePublished">August 14, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/pulmonary/article.aspx?id=1577" itemprop="url"> Transforming the Future of Lung Transplantation by Improving Access and Outcomes</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-07-02" itemprop="datePublished">July 2, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/pulmonary/journal.aspx?id=2625" itemprop="url"> Endobronchial Optical Coherence Tomography May Identify Pre-Symptomatic Disease Amongst Patients With Interstitial Lung Abnormalities</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-05-28" itemprop="datePublished">May 28, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third -padding--bottom"> <h3 class="content-tease__heading -large"> <a href="/urology/specialty.aspx?id=1005">Urology</a> </h3> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/urology/journal.aspx?id=2632" itemprop="url"> Multiparametric MRI Is Often False-Negative for Clinically Significant Prostate Cancer</a> </h3> <p itemprop="description"> <p><span>Chin-Lee Wu, MD, PhD, Douglas M. Dahl, MD, and colleagues found that 15% of patients who had negative prostate multiparametric MRI (mpMRI) were diagnosed by 20-core standard template biopsy as having clinically significant prostate cancer. They recommend considering standard biopsy regardless of negative mpMRI.</span></p></p> <p class="content-tease__related"> <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a>, <a href="/oncology/topic.aspx?id=1065" itemprop="relatedLink">Prostate Cancer</a>, <a href="/urology/specialty.aspx?id=1005" itemprop="relatedLink">Urology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-06-28" itemprop="datePublished">June 28, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/urology/journal.aspx?id=2621" itemprop="url"> Potential Strategy Identified for Treating Bone-Metastatic Clear Cell RCC</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-05-14" itemprop="datePublished">May 14, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/urology/journal.aspx?id=2601" itemprop="url"> Less Aggressive Protocol Suitable for Muscle-invasive Bladder Cancer in Noncystectomy Candidates</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-03-13" itemprop="datePublished">March 13, 2024</time> </p> </div> </div> </div> <p class="fat-link__wrapper u-no-margin u-text-centered"> <a class="fat-link -caret -large" href="/specialty-listing.aspx">View All Specialties</a> </p> </div> </section> <section class="topics-layout -no-border"> <div class="topics-layout__inner"> <div class="topics-layout__sidebar"> <h2 class="section-heading">Trending topics</h2> </div> <div class="topics-layout__main"> <ul class="topics-list" data-module="topics-list"> <li><a href="/neuro/topic.aspx?id=1044">ADHD</a></li> <li><a href="/research-and-innovation/topic.aspx?id=1111">Artificial Intelligence</a></li> <li><a href="/neuro/topic.aspx?id=1032">Female Mental Health</a></li> <li><a href="/ortho/topic.aspx?id=1009">Sports Medicine</a></li> <li><a href="/neuro/topic.aspx?id=1015">Stroke</a></li> </ul> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret" href="/topic-listing.aspx">View All</a> </p></div> </div> </section> <section class="layout-columns__left-split -padding--vertical -background--grey"> <div class="layout-columns -width--wide -centered -padding--bottom"> <div class="layout-columns__sidebar"> <div class="layout-columns__sidebar__content -padding--horizontal -padding--bottom"> <h2 class="section-heading">Education & Training Opportunities</h2> </div> </div> <div class="layout-columns__main"> <div class="layout-columns__main__content -padding--horizontal -padding--vertical--tablet-up"> <div class="layout-columns"> <div class="layout-columns__pod--half"> <div class="content-tease" itemscope itemtype="http://schema.org/Event"> <p class="content-tease__topic -large"> December 6-10, 2024</p> <h3 class="content-tease__heading" itemprop="name"> <a href="/oncology/event.aspx?id=1084" itemprop="url"> Conference: ASH 2024 Annual Meeting</a> </h3> <p class="content-metadata -border-bottom"> Conference</p> <p itemprop="description"> Leaders from the Mass General Cancer Center will present groundbreaking cancer research at this year’s ASH 2024 Annual Meeting, held December 6–10, 2024, both in-person in San Diego, CA, and virtually.</p> </div> </div> </div> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret" href="/event-education-listing.aspx">View All</a> </p> </div> </div> </div> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__sidebar"> <div class="layout-columns__sidebar__content -padding--horizontal -padding--bottom"> <h2 class="section-heading">Clinical Trials</h2> </div> </div> <div class="layout-columns__main"> <div class="layout-columns__main__content -padding--horizontal -padding--vertical--tablet-up"> <div class="layout-columns"> <div class="layout-columns__pod--half"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <a href="/neuro/specialty.aspx?id=1004">In Neuroscience</a> </p> </div> </div> <div class="layout-columns__pod--half"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <a href="/cardiovascular/specialty.aspx?id=1002">In Cardiovascular</a> </p> </div> </div> </div> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret" href="https://advances.massgeneral.org/clinical-trial-listing.aspx">View All</a> </p> </div> </div> </div> </section> <div class="-padding--horizontal -padding--vertical -background--white"> <style> #email-signup { /* 540px */ background-image: url(/assets/raw/email-signup/cardiovascular-sub-callout.jpg); } only screen and (-webkit-min-device-pixel-ratio: 2), only screen and (min--moz-device-pixel-ratio: 2), only screen and (-moz-min-device-pixel-ratio: 2), only screen and (-o-min-device-pixel-ratio: 2/1), only screen and (min-device-pixel-ratio: 2), only screen and (min-resolution: 192dpi), only screen and (min-resolution: 2dppx) { #email-signup { /* 1080 width */ background-image: url(/assets/raw/email-signup/cardiovascular-sub-callout.jpg); } } </style> <div class="content-container -width--wide -centered email-signup__wrapper" id="email-signup"> <div class="email-signup"> <img alt="Subscribe to the latest updates from Advances in Motion" class="email-signup__logo" src="/assets/images/logo-white.svg"> <h2 class="email-signup__heading">Subscribe to the latest updates from Advances in Motion</h2>  <meta http-equiv="Content-Type" content="text/html; charset=utf-8" /> <meta name="referrer" content="no-referrer-when-downgrade">  <script type="text/javascript" data-for="FA__DOMContentLoadedEventDispatch" src="https://massgeneral.tfaforms.net/js/FA__DOMContentLoadedEventDispatcher.js" defer></script> <script type="text/javascript"> document.addEventListener("FA__DOMContentLoaded", function(){ const FORM_TIME_START = Math.floor((new Date).getTime()/1000); let formElement = document.getElementById("tfa_0"); if (null === formElement) { formElement = document.getElementById("0"); } let appendJsTimerElement = function(){ let formTimeDiff = Math.floor((new Date).getTime()/1000) - FORM_TIME_START; let cumulatedTimeElement = document.getElementById("tfa_dbCumulatedTime"); if (null !== cumulatedTimeElement) { let cumulatedTime = parseInt(cumulatedTimeElement.value); if (null !== cumulatedTime && cumulatedTime > 0) { formTimeDiff += cumulatedTime; } } let jsTimeInput = document.createElement("input"); jsTimeInput.setAttribute("type", "hidden"); jsTimeInput.setAttribute("value", formTimeDiff.toString()); jsTimeInput.setAttribute("name", "tfa_dbElapsedJsTime"); jsTimeInput.setAttribute("id", "tfa_dbElapsedJsTime"); jsTimeInput.setAttribute("autocomplete", "off"); if (null !== formElement) { formElement.appendChild(jsTimeInput); } }; if (null !== formElement) { if(formElement.addEventListener){ formElement.addEventListener('submit', appendJsTimerElement, false); } else if(formElement.attachEvent){ formElement.attachEvent('onsubmit', appendJsTimerElement); } } }); </script> <link href="https://massgeneral.tfaforms.net/dist/form-builder/5.0.0/wforms-layout.css?v=20484c23150f9374e828ae7e95c879908749f33b" rel="stylesheet" type="text/css" /> <link href="https://massgeneral.tfaforms.net/uploads/themes/theme-7.css" rel="stylesheet" type="text/css" /> <link href="https://massgeneral.tfaforms.net/dist/form-builder/5.0.0/wforms-jsonly.css?v=20484c23150f9374e828ae7e95c879908749f33b" rel="alternate stylesheet" title="This stylesheet activated by javascript" type="text/css" /> <script type="text/javascript" src="https://massgeneral.tfaforms.net/wForms/3.11/js/wforms.js?v=20484c23150f9374e828ae7e95c879908749f33b"></script> <script type="text/javascript"> wFORMS.behaviors.prefill.skip = false; </script> <script type="text/javascript" src="https://massgeneral.tfaforms.net/wForms/3.11/js/localization-en_US.js?v=20484c23150f9374e828ae7e95c879908749f33b"></script>  <div class="wFormContainer" > <div class=""> <div class="wForm" id="538-WRPR" data-language="en_US" dir="ltr"> <div class="codesection" id="code-538"></div> <form method="post" action="https://massgeneral.tfaforms.net/api_v2/workflow/processor" class="hintsBelow labelsAbove" id="538"> <div class="oneField field-container-D " id="tfa_9-D"> <div aria-live="assertive"> <p class="marketo-signup__error"> Error: Please enter a valid email address. </p> </div> <p class="marketo-signup__input" data-module="label-float"> <label for="email-address"> Email Address </label> <input type="email" id="tfa_9" name="tfa_9" value="" data-marketo="email" > <button class="fat-button" type="submit" data-label="Submit" class="primaryAction" id="submit_button" value="Submit"> <span class="a11y-sr-only">Submit</span> </button> </p> <input type="hidden" id="tfa_10" name="tfa_10" value="Sub_MGB Advances" class=""><input type="hidden" id="tfa_12" name="tfa_12" value="AiM Sub Box" class=""> </div> <div style="clear:both"></div> <input type="hidden" value="538" name="tfa_dbFormId" id="tfa_dbFormId"> <input type="hidden" value="" name="tfa_dbResponseId" id="tfa_dbResponseId"> <input type="hidden" value="2be2ce342ee3a8558d26381d0bdb8739" name="tfa_dbControl" id="tfa_dbControl"> <input type="hidden" value="" name="tfa_dbWorkflowSessionUuid" id="tfa_dbWorkflowSessionUuid"> <input type="hidden" value="2" name="tfa_dbVersionId" id="tfa_dbVersionId"> <input type="hidden" value="" name="tfa_switchedoff" id="tfa_switchedoff"> </form> </div> </div> </div> <script id="open-telemetry-script" type="text/javascript" src="https://massgeneral.tfaforms.net/dist/open-telemetry/open-telemetry.152f594b0ae29ae89d4a.js" data-customer-id="1118" data-exporter-url="https://us-east-1-otel.formassembly.com/v1/traces" data-exporter-console="0" ></script> <script src="https://massgeneral.tfaforms.net/api_v2/sst/copy-and-paste"></script> </div> </div> </div> </div> </main>  <footer class="site-footer"> <div class="-padding--horizontal"> <nav aria-label="Footer links" class="content-container -width--wide -centered -padding--bottom"> <ul class="footer__nav" role="presentation"> <li> <a href="https://www.massgeneral.org/about">About Mass General</a> </li> <li> <a href="https://www.massgeneral.org/about/support">Giving</a> </li> <li> <a href="https://www.massgeneral.org/news/">News</a> </li> <li> <a href="https://www.massgeneral.org/notices/terms-of-use">Terms of Use</a> </li> <li> <a href="/contact-us.aspx">Contact Us</a> </li> </ul> </nav> <div class="content-container -width--wide -centered -padding--bottom"> <p class="u-text-centered"> <a class="footer__logo" href="http://www.massgeneral.org"> <img alt="MGH" src="/assets/images/logo-color.svg"> <span class="a11y-sr-only">Massachusetts General Hospital</span> </a> </p> <ul class="footer__social" role="presentation"> <li> <a href="https://twitter.com/MassGeneralNews"> <svg width="19" height="15" xmlns=http://www.w3.org/2000/svg viewBox="0 0 18.81 17"><path d="m14.81,0h2.89l-6.3,7.2,7.41,9.8h-5.8l-4.55-5.94-5.2,5.94H.37l6.74-7.7L0,0h5.95l4.11,5.43L14.81,0Zm-1.01,15.28h1.6L5.08,1.63h-1.72l10.43,13.64Z"/></svg> </a> </li> <li> <a href="https://www.facebook.com/massgeneral/"> <svg xmlns="http://www.w3.org/2000/svg" width="9" height="19"><path fill-rule="evenodd" fill="#007EA3" d="M0 6.284h1.929V4.373c0-.84.021-2.139.621-2.943C3.182.578 4.05 0 5.543 0 7.975 0 9 .353 9 .353l-.482 2.911s-.804-.237-1.554-.237-1.421.273-1.421 1.037V6.284h3.075l-.215 2.841h-2.86V19H1.929V9.125H0V6.284z"/></svg> </a> </li> <li> <a href="http://www.youtube.com/user/MassGeneralHospital"> <svg xmlns="http://www.w3.org/2000/svg" width="23" height="17"><path fill-rule="evenodd" fill="#007EA3" d="M22.77 13.325s-.224 1.666-.914 2.399c-.875.963-1.855.968-2.305 1.024-3.218.244-8.051.252-8.051.252s-5.98-.057-7.82-.243c-.512-.101-1.661-.07-2.536-1.033-.69-.733-.914-2.399-.914-2.399S0 11.369 0 9.413V7.579c0-1.956.23-3.912.23-3.912s.224-1.665.914-2.399C2.019.306 2.999.301 3.448.244 6.667 0 11.495 0 11.495 0h.01s4.828 0 8.046.244c.45.057 1.43.062 2.305 1.024.69.734.914 2.399.914 2.399S23 5.623 23 7.579v1.834c0 1.956-.23 3.912-.23 3.912zm-8.519-4.481L9.124 5.246l.001 6.389 5.126-2.791zm-5.127-4v.358l5.887 3.228.328-.179-6.215-3.407z"/></svg> </a> </li> <li> <a href="https://www.linkedin.com/company/massachusetts-general-hospital"> <svg xmlns="http://www.w3.org/2000/svg" width="18" height="18"><path fill-rule="evenodd" fill="#007EA3" d="M14.273 18v-5.846c0-1.396-.027-3.188-1.939-3.188-1.94 0-2.236 1.518-2.236 3.085V18H6.371V5.977h3.575v1.642h.052c.498-.945 1.715-1.941 3.53-1.941 3.775 0 4.472 2.49 4.472 5.728V18h-3.727zM2.164 4.333A2.164 2.164 0 0 1 0 2.166a2.164 2.164 0 1 1 4.327 0 2.166 2.166 0 0 1-2.163 2.167zM4.031 18H.296V5.977h3.735V18z"/></svg> </a> </li> <li> <a href="https://www.doximity.com/pages/hospitals/ma/boston/massachusetts-general-hospital"> <svg xmlns="http://www.w3.org/2000/svg" width="17.583" height="18" viewBox="8.024 95.826 17.583 18"><g fill="#007EA3"><path d="M23.207 104.657c.034-.062.02-.115.02-.168v-5.142c0-.413.173-.586.58-.586h1.278c.34 0 .523.178.523.52v13.803c0 .332-.178.52-.51.52-.45.004-.9.004-1.353 0-.32 0-.513-.197-.513-.52v-1.368c-.062.03-.087.077-.115.12-.442.614-.965 1.138-1.632 1.498-.788.427-1.637.557-2.52.46-1.215-.13-2.232-.657-3.068-1.545-.725-.772-1.152-1.7-1.334-2.736-.207-1.147-.163-2.29.22-3.398.65-1.853 1.925-3.024 3.874-3.36 1.642-.288 3.058.197 4.176 1.464.13.134.245.283.374.437zm-3.216 7.137c1.13-.02 1.978-.47 2.597-1.334.658-.917.812-1.95.605-3.043-.302-1.58-1.59-2.81-3.35-2.698-.96.06-1.766.464-2.3 1.266-.9 1.354-.945 2.793-.182 4.214.557 1.047 1.494 1.566 2.63 1.594zM15.988 95.835c.355-.024.71.004 1.06.042.04.005.078.01.116.024.144.054.226.184.207.333-.023.144-.143.163-.258.173-.624.053-1.23.177-1.82.394-.993.365-1.885.902-2.71 1.555-1.1.864-2.056 1.862-2.81 3.048-.522.82-.93 1.69-1.118 2.65-.02.104-.033.215-.058.32-.024.107-.052.208-.187.227-.13.014-.265-.062-.317-.187-.053-.13-.053-.27-.058-.404-.058-1.244.12-2.45.605-3.6.33-.783.796-1.48 1.368-2.108 1.277-1.412 2.894-2.155 4.76-2.41.203-.03.41-.053.615-.062.202 0 .403.005.605.005zM11.342 105.18c.014-1.512.494-2.842 1.53-3.96.84-.907 1.883-1.44 3.083-1.69.687-.144 1.383-.168 2.08-.1l.104.013c.143.03.24.125.23.24-.015.148-.145.144-.25.163-.173.024-.35.04-.52.072-.916.178-1.727.586-2.48 1.124-.918.658-1.71 1.435-2.343 2.37-.485.716-.854 1.48-.984 2.344-.015.105-.024.23-.178.23-.14 0-.216-.09-.24-.26-.04-.176-.028-.364-.033-.546z"/></g></svg> </a> </li> </ul> <p class="footer__address"> <a href="https://www.google.com/maps/dir/''/55+Fruit+St,+Boston,+MA+02114/@42.3631581,-71.0710274,17z/data=!3m1!4b1!4m8!4m7!1m0!1m5!1m1!1s0x89e370999524529b:0x10e737717f2daf80!2m2!1d-71.0688334!2d42.3631542" itemprop="address" itemscope itemtype="http://schema.org/PostalAddress"> <span itemprop="streetAddress">55 Fruit Street</span> <span itemprop="addressLocality">Boston</span>, <span itemprop="addressRegion">MA</span> <span itemprop="postalCode">02114</span> </a> <span class="footer__phone"> Phone: <a href="tel:6177262000" itemprop="telephone">617-726-2000</a> </span> </p> <p> Copyright © 2007-2024. The General Hospital Corporation. All Rights Reserved. </p> </div> </div> <div class="content-container -padding--horizontal -padding--vertical -background--grey"> <ul class="footer__partners -width--wide -centered" role="presentation"> <li> <a href="https://www.massgeneral.org/education/about"> <img alt="Harvard teaching hospital logo" src="/assets/images/logo-hms.svg" width="170"> </a> </li> <li> <a href="https://www.massgeneralbrigham.org/"> <img alt="Mass General Brigham logo" src="/assets/images/MassGeneralBrigham-grey.svg" width="200"> </a> </li> <li> <a href="https://www.massgeneral.org/about/leadership"> <img alt="Physicians" src="/assets/images/logo-physicians.svg" width="177"> </a> </li> <li> <a href="http://protomag.com/"> <img alt="Proto Magazine Logo" src="/assets/images/logo-proto.svg" width="117"> </a> </li> </ul> </div> </footer> <script src="/assets/scripts/index.js"></script>  </body> </html>