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top:0;"> <div> <a href="https://www.informatics.jax.org/" style="background-color: transparent"> <img src="https://www.informatics.jax.org/webshare/images/mgi_logo.gif" border=0> </a> </div> <span class="logoFooterContainer"> &nbsp;&nbsp;<a class="logoFooterAnchor" href="https://www.informatics.jax.org/mgihome/projects/aboutmgi.shtml">About</a> &nbsp;&nbsp;<a class="logoFooterAnchor" href="https://www.informatics.jax.org/mgihome/homepages/help.shtml">Help</a> &nbsp;&nbsp;<a class="logoFooterAnchor" href="https://www.informatics.jax.org/faq/FAQ.shtml">FAQ</a> </span> </div> <div id="agr_logo" style="float: right; padding-top: 3px; padding-right: 5px;"> <a href="https://globalbiodata.org/" target="_blank"><img src="https://www.informatics.jax.org/webshare/images/gcbr_logo.png" style="height:65px;margin-right:10px;margin-left:10px;"></a> <a href="https://www.alliancegenome.org/" target="_blank"><img src="https://www.informatics.jax.org/webshare/images/agr_logo_smallest.png" style="height:70px"></a> </div> <div id="templateSearchTool" style="float:right; top:15px; margin-right: 5px;"> <style> .lightYellow { background-color: #ffd; } .lightGray { background-color: #dadada; } .italic { font-style: italic; } </style> <form action="https://www.informatics.jax.org/quicksearch/summary" method="get"> <table> <tr> <td> <a onClick="return false;" href="https://www.informatics.jax.org/userhelp/searchtool_help.shtml" onMouseOver="if (window.jQuery) { setTimeout(function () { $('td[valign=TOP]').css({'background-color' : '#efefef'}); }, 750); }; return overlib('You can:<ul class=\'searchToolHelp\'><li>Search for genome features by name, symbol, synonym, homolog, allele, or accession ID:</li> <ul><li>p53 protein cell cycle DNA damage</li><li>Notch1</li><li>NM_053172</li><li>AT3</li></ul><li>Search for genome features and vocabulary terms by keywords or accession ID. Use several keywords to find the most relevant results:</li><ul><li>GO:0004713</li><li>resistance to fatty liver development</li><li>vitamin D receptor</li><li>lymphocyte function antigen immunodeficiency</li> </ul><li>Search for genome features by mouse genome location. Use a chromosome, point coordinate, or coordinate range:</li><ul><li>Chr1</li><li>Chr1:194732198</li><li>Chr1:194732198-294732198</li></ul> <li>Use asterisks (*) for wildcards at the end of partial words or genomic symbols:</li><ul><li>Pax*</li><li>embr* development</li><li>hippocamp* pyramid* cell layer</li></ul><li>Use quotation marks (&quot;&nbsp;&quot;) to indicate phrases:</li> <ul><li>&quot;hair follicle&quot; development</li><li>&quot;amyotrophic lateral sclerosis&quot;</li></ul><li>Use angle brackets to indicate superscript:</li><ul><li>Pax6&lt;10Neu&gt; for Pax6<sup>10Neu</sup></li></ul><li>Mix IDs, symbols, and keywords in a list:</li><ul><li>Nmt2, NM_013627, Acbd7, hair follicle development</li></ul></ul>Advanced searches are listed under the Search menu.<BR/>See <a href=\'https://www.informatics.jax.org/userhelp/QUICK_SEARCH_help.shtml\'>Using the Quick Search Tool</a> for more information.', STICKY, CAPTION, 'Quick Search Tips', CENTER, BELOW, WIDTH, 450, DELAY, 600, CLOSECLICK, CLOSETEXT, 'Close X');" onMouseOut="nd();"> <img src="https://www.informatics.jax.org/webshare/images/help_small_transp.gif" border="0"> </a> </td> <td> <select id="queryTypeTop" name="queryType" class="lightGray"> <option value="exactPhrase" selected="">Keywords, Symbols, or IDs (exact phrase)</option> <option value="keywords">Keywords, Symbols, or IDs</option> <option value="mouseLocation">Mouse Location</option> <option value="humanLocation">Human Location</option> </select> </td> <td> <input name="query" id="searchToolTextArea" class="lightYellow italic" value=" Type your search here" onFocus="if(this.defaultValue==this.value) this.value=''; $('#searchToolTextArea').removeClass('italic');" size="30"> </td> <td> <input name="submit" type="submit" class="searchToolButton" value="Quick Search" onclick="return verifySearchToolParms();"> </td> </tr> </table> </form> </div> <div style="position:absolute; top:4px; left:150px;"> <iframe style="border:none" src="/webshare/html/notice.html" width="400" height="40"></iframe> </div> </div> <!-- Menu Bar Start --> <div id="navBarMenu" class="yuimenubar"> <div class="bd"> <ul class="first-of-type"> <!-- Searches Start --> <li class="yuimenubaritem first-of-type"><a class="yuimenubaritemlabel" href="https://www.informatics.jax.org/allsearch.shtml">Search</a> <div id="navBarSearch" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/allsearch.shtml" title="">All Search Tools</a></li> <!-- Marker Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Genes</a> <div id="navBarGenes" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/marker/" onMouseOver="return overlib('Search for genes and genome features by symbol, name, location, gene ontology classification or phenotype.',ANCHOR, 'navBarGenes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Genes &amp; Markers Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/batch" onMouseOver="return overlib('Input a list of gene IDs or symbols and retrieve other database IDs and gene attributes (e.g. phenotypes, GO).',ANCHOR, 'navBarGenes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Batch Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="http://jbrowse.informatics.jax.org/?data=data/GRCm39" onMouseOver="return overlib('Create a graphical display of genome features from regions of the mouse genome.',ANCHOR, 'navBarGenes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> JBrowse Genome Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/mgv/" onMouseOver="return overlib('Compare genome features of de novo sequenced mouse strains.',ANCHOR, 'navBarGenes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Multiple Genome Viewer (MGV)</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/genes.shtml">More</a></li> </ul> </div> </div> </li> <!-- Pheno Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Phenotypes</a> <div id="navBarPhenotypes" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/allele/" onMouseOver="return overlib('Search for mutations or QTL based on phenotype, human disease, mutation type, gene, or genome location.',ANCHOR, 'navBarPhenotypes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Phenotypes, Alleles &amp; Diseases Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/mp_ontology" onMouseOver="return overlib('Search for a phenotype term to find relevant mutant genotypes.',ANCHOR, 'navBarPhenotypes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Mammalian Phenotype (MP) Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/disease" onMouseOver="return overlib('Browse for a human disease or condition term to find mouse models.',ANCHOR, 'navBarPhenotypes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Human Disease (DO) Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/hp_ontology" onMouseOver="return overlib('Search for a human phenotype ontology term to find relevant human diseases.',ANCHOR, 'navBarPhenotypes', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Human Phenotype (HPO) Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/phenotypes.shtml">More</a></li> </ul> </div> </div> </li> <!-- Human Mouse Disease Connection --> <li class="yuimenuitem"><a id="navBarHMDC" class="yuimenuitemlabel" href="https://www.informatics.jax.org/diseasePortal" onMouseOver="return overlib('Human-Mouse: Disease Connection', ANCHOR, 'navBarHMDC', ANCHORALIGN, 1.0,0.5,0,0.5);" onMouseOut="nd();"> Human Disease</a> </li> <!-- Expression Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Expression</a> <div id="navBarExpression" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/gxd/" onMouseOver="return overlib('Search for detailed gene expression assay results.',ANCHOR, 'navBarExpression', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Gene Expression Data Search</a></li> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/gxdlit" onMouseOver="return overlib('Search for references on gene expression during development.',ANCHOR, 'navBarExpression', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Gene Expression Literature Search</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/gxd/anatomy/EMAPA:16039" onMouseOver="return overlib('Search or browse for anatomical structures; includes links to associated expression results.',ANCHOR, 'navBarExpression', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Mouse Developmental Anatomy Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/gxd/htexp_index" onMouseOver="return overlib('Search for experiments using sample metadata annotations.',ANCHOR, 'navBarExpression', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> RNA-Seq and Microarray Experiment Search</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/expression.shtml">More</a></li> </ul> </div> </div> </li> <!-- Recombinase --> <li class="yuimenuitem"><a id="navBarCre" class="yuimenuitemlabel" href="https://www.informatics.jax.org/home/recombinase" onMouseOver="return overlib('Get recombinase (cre) activity data for knock-in and transgene alleles.',ANCHOR, 'navBarCre', ANCHORALIGN, 1.0,0.5,0,0.5);" onMouseOut="nd();"> Recombinase (cre)</a></li> <!-- GO Functional Annotations Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Function</a> <div id="navBarFunction" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/gene_ontology" onMouseOver="return overlib('Browse the Gene Ontology and mouse annotations in MGI.',ANCHOR, 'navBarFunction', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> GO Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/marker/" onMouseOver="return overlib('Search for genes and genome features by symbol, name, location, gene ontology classification or phenotype.',ANCHOR, 'navBarFunction', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Genes &amp; Markers Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/batch" onMouseOver="return overlib('Obtain sets of MGI IDs for use in GO tools.',ANCHOR, 'navBarFunction', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Batch Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/function.shtml">More</a></li> </ul> </div> </div> </li> <!-- Strains Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Strains / SNPs</a> <div id="navBarStrains" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/home/strain" onMouseOver="return overlib('Search for strains by name, synonyms, or attributes.',ANCHOR, 'navBarStrains', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();">Strain Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/snp" onMouseOver="return overlib('Search for SNPs by strain(s), SNP attributes, genomic position, or associated genes.',ANCHOR, 'navBarStrains', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> SNP Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/mgv/" onMouseOver="return overlib('Compare genome features of de novo sequenced mouse strains.',ANCHOR, 'navBarStrains', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Multiple Genome Viewer (MGV)</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/home/strain">More</a></li> </ul> </div> </div> </li> <!-- Homology Submenu --> <li class="yuimenuitem"><a id="navBarHomology" class="yuimenuitemlabel" href="https://www.informatics.jax.org/homology.shtml" onMouseOver="return overlib('Find out more about Homology relationships in MGI.',ANCHOR, 'navBarHomology', ANCHORALIGN, 1.0,0.5,0,0.5);" onMouseOut="nd();"> Homology</a></li> <!-- MTB --> <li class="yuimenuitem"><a id="navBarMTB" class="yuimenuitemlabel" href="https://tumor.informatics.jax.org/mtbwi/index.do" onMouseOver="return overlib('MTB provides information on the frequency, pathology, and genetics of spontaneous and induced tumors in mice.',ANCHOR, 'navBarMTB', ANCHORALIGN, 1.0,0.5,0,0.5);" onMouseOut="nd();"> Tumors</a></li> <!-- Sequence Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Sequence Searches</a> <div id="navBarSequences" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://blast.ncbi.nlm.nih.gov/Blast.cgi" onMouseOver="return overlib('Search for sequence similarity using BLAST at NCBI.',ANCHOR, 'navBarSequences', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> BLAST at NCBI</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="http://jbrowse.informatics.jax.org/?data=data/GRCm39" onMouseOver="return overlib('Create a graphical display of genome features from regions of the mouse genome.',ANCHOR, 'navBarSequences', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> JBrowse Genome Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/batch" onMouseOver="return overlib('Input a list of gene IDs or symbols and retrieve other database IDs and gene attributes (e.g. phenotypes, GO).',ANCHOR, 'navBarSequences', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Batch Query</a></li> </ul> </div> </div> </li> <!-- References Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">References</a> <div id="navBarReferences" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/reference" onMouseOver="return overlib('Search for references (with abstracts) by title, author, journal, year, or abstract.',ANCHOR, 'navBarReferences', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Reference Query</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/gxdlit" onMouseOver="return overlib('Search for references on gene expression during development.',ANCHOR, 'navBarReferences', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Gene Expression Literature Query</a></li> </ul> </div> </div> </li> <!-- Vocabularies Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Ontologies</a> <div id="navBarVocabularies" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem first-of-type"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/gene_ontology" onMouseOver="return overlib('Browse the Gene Ontology and mouse annotations in MGI.',ANCHOR, 'navBarVocabularies', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> GO Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/disease" onMouseOver="return overlib('Browse for a human disease or condition term to find mouse models.',ANCHOR, 'navBarVocabularies', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Human Disease (DO) Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/mp_ontology" onMouseOver="return overlib('Search for a phenotype term to find relevant mutant genotypes.',ANCHOR, 'navBarVocabularies', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Mammalian Phenotype (MP) Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/gxd/anatomy/EMAPA:16039" onMouseOver="return overlib('Search or browse for anatomical structures; includes links to associated expression results.',ANCHOR, 'navBarVocabularies', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Mouse Developmental Anatomy Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/gxd/ma_ontology" onMouseOver="return overlib('An extensive ontology of anatomical structures for the postnatal mouse.',ANCHOR, 'navBarVocabularies', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Adult Mouse Anatomy Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/vocab/hp_ontology" onMouseOver="return overlib('Search for a human phenotype ontology term to find relevant human diseases.',ANCHOR, 'navBarVocabularies', ANCHORALIGN, 'UR', 'UL');" onMouseOut="nd();"> Human Phenotype (HPO) Browser</a></li> </ul> </div> </div> </li> <!-- Non-Drop-Downs --> <li class="yuimenuitem"><a id="navBarBatch" class="yuimenuitemlabel" href="https://www.informatics.jax.org/batch" onMouseOver="return overlib('Input a list of gene IDs or symbols and retrieve other database IDs and gene attributes (e.g. phenotypes, GO).',ANCHOR, 'navBarBatch', ANCHORALIGN, 1.0,0.5,0,0.5);" onMouseOut="nd();"> Batch Query</a></li> <li class="yuimenuitem"><a id="navBarMine" class="yuimenuitemlabel" href="https://www.mousemine.org" onMouseOver="return overlib('Access MGI data via InterMine.',ANCHOR, 'navBarMine', ANCHORALIGN, 1.0,0.5,0,0.5);" onMouseOut="nd();"> MouseMine</a></li> <!-- Vocabularies Submenu --> <li class="yuimenuitem"><a class="yuimenuitemlabel">Mouse Genome Browsers</a> <div id="navBarGenomeBrowsers" class="yuimenu"> <div class="bd"> <ul class="first-of-type"> <li class="yuimenuitem"><a id="navBarJBrowse" class="yuimenuitemlabel" href="http://jbrowse.informatics.jax.org/?data=data/GRCm39" onMouseOver="return overlib('Create a graphical display of genome features from regions of the mouse genome.',ANCHOR, 'navBarJBrowse', ANCHORALIGN, 1.0,0.5,0,0.5);" onMouseOut="nd();"> JBrowse Genome Browser</a></li> <li class="yuimenuitem"><a class="yuimenuitemlabel" href="https://www.informatics.jax.org/mgv/" onMouseOver="return overlib('Compare genome features of de novo sequenced mouse strains.',ANCHOR, 'navBarJBrowse', ANCHORALIGN, 'UR', 'UL');" 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