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Pairwise kinship inference and pedigree reconstruction using 91 microhaplotypes - Peeref
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<strong>My Account</strong> </a> </li> </ul> <ul class="nav navbar-nav navbar-right" style="display: inline-flex; align-items: center; margin-left: 20px;"> <li id="language"> <a href="javascript:"> <div class="current"> <i class="ivu-icon ivu-icon-md-globe"></i> EN </div> </a> <div class="selection"> <a rel="alternate" hreflang="en" href="https://www.peeref.com/works/82936722" > <span>English</span> </a> <a rel="alternate" hreflang="zh" href="https://www.peeref.com/zh/works/82936722" > <span>中文</span> </a> </div> </li> </ul> </ul> </div> </nav> <main> <div id="top-info-banner" class="container-fluid mb-0"> <div class="container"> <div class="d-flex align-items-center" style="margin-top: 30px;"> <span class="text-white"> <strong class="f18">☆</strong> <span class="f16">4.5</span> </span> <span class="mx-3"></span> <span class="tag">Article</span> </div> <h1 class="title title-for-article"> Pairwise kinship inference and pedigree reconstruction using 91 microhaplotypes </h1> <div class="help-links-left"> <p class="pub-info"> FORENSIC SCIENCE INTERNATIONAL-GENETICS (2024) </p> </div> </div> </div> <div id="article-sticky-navbar"> <div class="container"> <div class="d-flex justify-content-between flex-wrap flex-md-nowrap"> <div class="d-flex align-items-center mb-2"> <ul class="nav nav-underline f16 font-weight-bold"> <li class="active"> <a href="javascript:;"> Overview </a> </li> <li class=""> <a href="https://www.peeref.com/works/82936722/comments"> Write a Review </a> </li> </ul> </div> <div class="d-flex align-items-center justify-content-md-end flex-wrap flex-md-nowrap"> <div class="mr-3 mt-3 mt-md-0 flex-shrink-0"> <a href="https://doi.org/10.1016/j.fsigen.2024.103090" target="_blank" class="btn btn-warning btn-circle"> <i class="ivu-icon ivu-icon-md-copy f16"></i> <strong>Get Full Text</strong> </a> </div> <div class="mr-3 mt-3 mt-md-0 flex-shrink-0"> <a href="https://www.peeref.com/works/82936722/add-to-collection" class="btn btn-success btn-circle"> <strong>Add to Collection</strong> </a> </div> <div class="mr-3 mt-3 mt-md-0 flex-shrink-0"> <button class="btn btn-success btn-circle" id="reading-btn"> <strong>Further Reading</strong> </button> </div> <div class="flex-shrink-0 mt-3 mt-md-0"> <div class="dropdown"> <button class="font-weight-bold f24 ivu-btn ivu-btn-default ivu-btn-circle ivu-btn-large ivu-btn-icon-only dropdown-toggle" data-toggle="dropdown"> <i class="ivu-icon ivu-icon-md-more"></i> </button> <ul class="dropdown-menu dropdown-menu-right"> <li> <a href="#" data-target="#export-citation" data-toggle="modal"> <i class="ivu-icon ivu-icon-md-quote text-muted mr-1"></i> Export Citation </a> </li> <li> <a href="#" data-target="#share-paper" data-toggle="modal"> <i class="ivu-icon ivu-icon-md-share-alt text-muted mr-1"></i> Share Paper </a> </li> <li> <a href="https://www.peeref.com/works/82936722/references"> <i class="ivu-icon ivu-icon-md-list text-muted mr-1"></i> References </a> </li> </ul> </div> </div> </div> </div> </div> </div> <div id="article-details" class="container"> <div class="col-md-4 px-0 pr-md-3"> <div class="f15 panel-box rounded shadow-none border"> <div class="mb-3 pb-3"> <h4 class="mt-0">Journal</h4> <div class="f16"> <h5 class="title f16"> <a href="https://www.peeref.com/journals/2908/forensic-science-international-genetics"> FORENSIC SCIENCE INTERNATIONAL-GENETICS </a> </h5> <span> Volume 72, Issue -, Pages - </span> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Publisher</h4> <div class="f16"> <h5 class="title f16 text-primary"> ELSEVIER IRELAND LTD </h5> <div class="my-2"> DOI: 10.1016/j.fsigen.2024.103090 </div> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Keywords</h4> <div class="f16"> Relatedness; Kinship; Microhaplotypes (MH); Likelihood ratio (LR); Pedigree </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Categories</h4> <div class="f16"> <span class="d-block"> <a href="https://www.peeref.com/works/list?category=Genetics+%26+Heredity" target="_blank" class="text-dark btn btn-link p-0 text-left"> Genetics & Heredity </a> </span> <span class="d-block"> <a href="https://www.peeref.com/works/list?category=Medicine%2C+Legal" target="_blank" class="text-dark btn btn-link p-0 text-left"> Medicine, Legal </a> </span> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Funding</h4> <div class="f16"> <ol class=""> <li>National Natural Science Foundation of China [82230064, 82072120, 81630054]</li> </ol> </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 text-center">Ask authors/readers for more resources</h4> <div class="requests"> <div class="requests-item"> <div class="icon"> <img src="https://peeref-open.s3.amazonaws.com/images/file.png" alt=""> </div> <h4>Protocol</h4> <p> <a href="https://www.peeref.com/works/82936722/resource" class="btn btn-outline-primary btn-sm"> Community support </a> </p> </div> <div class="requests-item"> <div class="icon"> <img src="https://peeref-open.s3.amazonaws.com/images/experiment.png" alt=""> </div> <h4>Reagent</h4> <p> <a href="https://www.peeref.com/works/82936722/resource" class="btn btn-outline-primary btn-sm"> Community support </a> </p> </div> </div> </div> </div> <div class="col-md-8 px-0 pl-md-3"> <div id="article-summary-panel" class="mb-4"> <ul class="nav nav-tabs" style="list-style: none; padding-left: 0;"> <li class="active"> <a href="#ai_summary" data-toggle="tab" class="summary-tab mx-0 f16 text-dark"> <strong>Automated Summary</strong> <strong class="text-danger ml-1"><i>New</i></strong> </a> </li> <li class=""> <a href="#raw_abstract" data-toggle="tab" class="abstract-tab mx-0 f16 text-dark"> <strong>Abstract</strong> </a> </li> </ul> <div class="tab-content border border-top-0"> <div id="ai_summary" class="tab-pane active"> <div class="summary-panel panel-box mb-0 rounded shadow-none"> <div class="f16">This study solves the problem of kinship inference without prior assumptions by genotyping and calculating the likelihood ratio to infer the relatedness of individuals. It is found that increasing the number of polymorphic loci can improve the accuracy of kinship inference, and correct classification can be achieved by expanding the suspected relationship. In addition, this method can also be used to reconstruct the pedigree of multiple individuals with unknown relationships.</div> </div> </div> <div id="raw_abstract" class="tab-pane "> <div class="abstract-panel panel-box mb-0 rounded shadow-none"> <div class="f16">Kinship inference has been a major issue in forensic genetics, and it remains to be solved when there is no prior hypothesis and the relationships between multiple individuals are unknown. In this study, we genotyped 91 microhaplotypes from 46 pedigree samples using massive parallel sequencing and inferred their relatedness by calculating the likelihood ratio (LR). Based on simulated and real data, different treatments were applied in the presence and absence of relatedness assumptions. The pedigree of multiple individuals was reconstructed by calculating pedigree likelihoods based on real pedigree samples. The results showed that the 91 MHs could discriminate pairs of second-degree relatives from unrelated individuals. And more highly polymorphic loci were needed to discriminate the pairs of second-degree or more distant relative from other degrees of relationship, but correct classification could be obtained by expanding the suspected relationship searched to other relationships with lower LR values. Multiple individuals with unknown relationships can be successfully reconstructed if they are closely related. Our study provides a solution for kinship inference when there are no prior assumptions, and explores the possibility of pedigree reconstruction when the relationships of multiple individuals are unknown.</div> </div> </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">Authors</h4> <div class="mb-3"> <article-authors tid="82936722" list="[{"name":"Yifan Wei","sequence":1},{"name":"Qiang Zhu","sequence":2},{"name":"Haoyu Wang","sequence":3},{"name":"Yueyan Cao","sequence":4},{"name":"Xi Li","sequence":5},{"name":"Xiaokang Zhang","sequence":6},{"name":"Yufang Wang","sequence":7},{"name":"Ji Zhang","sequence":8}]" verified="[]" page="work" ></article-authors> </div> <div class="alert alert-warning mb-0"> <h5 class="mt-0 bg-warning text-dark px-3 rounded d-inline-block"> I am an author on this paper </h5> <div class="font-weight-bold f13"> Click your name to claim this paper and add it to your profile. </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">Reviews</h4> <div class="d-flex flex-wrap flex-md-nowrap"> <div class="flex-grow-1"> <h4 class="f16"> Primary Rating <a href="javascript:;" data-toggle="tooltip" data-placement="right" title="The primary rating indicates the level of overall quality for the paper."> <i class="ivu-icon ivu-icon-md-help-circle f18 ml-2"></i> </a> </h4> <div class="d-flex flex-wrap flex-md-nowrap align-items-center alert mb-0"> <div class="d-flex align-items-center justify-content-center"> <Rate disabled allow-half value="4.5" style="font-size: 28px;"></Rate> <strong class="f20 m-3" style="color: #f5a623;">4.5</strong> </div> <div class="text-muted mx-4"> Not enough ratings </div> </div> <h4 class="f16"> Secondary Ratings <a href="javascript:;" data-toggle="tooltip" data-placement="right" title="Secondary ratings independently reflect strengths or weaknesses of the paper."> <i class="ivu-icon ivu-icon-md-help-circle f18 ml-2"></i> </a> </h4> <div class="d-flex flex-wrap flex-md-nowrap alert"> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">Novelty</h5> <strong class="mx-4">-</strong> </div> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">Significance</h5> <strong class="mx-4">-</strong> </div> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">Scientific rigor</h5> <strong class="mx-4">-</strong> </div> </div> </div> <div class="flex-shrink-0"> <div class="border bg-light py-2 px-4"> <h5 class="mb-1">Rate this paper</h5> <Rate class="f24" @on-change="function(value){ location.href='https://www.peeref.com/works/82936722/comments?rating='+value }"></Rate> </div> </div> </div> </div> <div id="collection" class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">Recommended</h4> <div class="my-3"> <ul class="nav nav-pills border-bottom pb-3" style="list-style: none; padding-left: 0;"> <li class="active"> <a href="#articles_from_related" data-toggle="tab" class="mx-0 f15"> <strong>Related</strong> </a> </li> <li class=""> <a href="#articles_from_authors" data-toggle="tab" class="mx-0 f15"> <strong>From Same Authors</strong> </a> </li> <li class=""> <a href="#articles_from_journal" data-toggle="tab" class="mx-0 f15"> <strong>From Same Journal</strong> </a> </li> </ul> <div class="tab-content"> <div id="articles_from_related" class="tab-pane active"> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/82931435" class="text-dark hover-underline">Pairwise kinship inference and pedigree reconstruction using 91 microhaplotypes</a> </h4> <p class="text-ellipsis-2">Yifan Wei, Qiang Zhu, Haoyu Wang, Yueyan Cao, Xi Li, Xiaokang Zhang, Yufang Wang, Ji Zhang</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2886.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study addresses the issue of kinship inference when there are no prior assumptions and the relationships between multiple individuals are unknown. It uses genotyping and likelihood ratio calculation to infer relatedness and reconstruct pedigrees. The results show that 91 microhaplotypes can discriminate second-degree relatives from unrelated individuals, and more loci are needed to distinguish more distant relatives. Correct classification can be achieved by expanding the suspected relationships. This study provides a new solution for kinship inference. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/82931435/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Multidisciplinary Sciences </span> </div> <h4> <a href="https://www.peeref.com/works/28855387" class="text-dark hover-underline">Kinship composition in mammals</a> </h4> <p class="text-ellipsis-2">Andre S. Pereira, Delphine De Moor, Catarina Casanova, Lauren J. N. Brent</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/10246.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> Understanding the evolution of group-living and cooperation requires knowledge of the kinship composition in animal groups. This study presents initial findings on the kinship composition of mammalian groups, showing that social mammals often live with unrelated individuals of the same sex. These results emphasize the importance of considering both indirect and direct fitness benefits in the evolution of sociality. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">ROYAL SOCIETY OPEN SCIENCE</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/28855387/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biotechnology & Applied Microbiology </span> </div> <h4> <a href="https://www.peeref.com/works/27217671" class="text-dark hover-underline">Inferring biological kinship in ancient datasets: comparing the response of ancient DNA-specific software packages to low coverage data</a> </h4> <p class="text-ellipsis-2">William A. Marsh, Selina Brace, Ian Barnes</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1255.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The use of archaeogenetic techniques, in combination with traditional methods, allows for improved interpretation of burial practices, cultural behaviors, and societal stratification in ancient societies. However, questions remain regarding the accuracy of these techniques, especially when it comes to low coverage datasets obtained from degraded ancient material. A study comparing six commonly used kinship identification software methods revealed differences in performance, emphasizing the importance of applying multiple methods for authentication of kin relationships in ancient material. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BMC GENOMICS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/27217671/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83039808" class="text-dark hover-underline">Application of a newly constructed NGS panel with 45 X-linked microhaplotypes demonstrates the unique value of X-MH for kinship testing and mixture analysis</a> </h4> <p class="text-ellipsis-2">Guanju Ma, Kailiang Liu, Chaolong Lu, Qingqing Du, Mengjie Zhang, Qian Wang, Guangping Fu, Junyan Wang, Chunling Ma, Bin Cong, Shujin Li, Lihong Fu</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2908.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study screened 63 X-MHs, evaluated their performance, and calculated population parameters. The panel performed well in personal identification and paternity testing, and showed unique advantages in complex kinship and male DNA mixture analyses. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83039808/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/25558075" class="text-dark hover-underline">State of the Art for Microhaplotypes</a> </h4> <p class="text-ellipsis-2">Kenneth K. Kidd, Andrew J. Pakstis</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/9770.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> In recent years, there has been a significant increase in the number of publications on microhaplotypes, which have proven to be highly informative in various areas of forensic DNA analysis. Microhaplotypes can be measured using different indicators and have important applications in parentage testing and missing persons cases. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">GENES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/25558075/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemical Research Methods </span> </div> <h4> <a href="https://www.peeref.com/works/26436098" class="text-dark hover-underline">Privacy-aware estimation of relatedness in admixed populations</a> </h4> <p class="text-ellipsis-2">Su Wang, Miran Kim, Wentao Li, Xiaoqian Jiang, Han Chen, Arif Harmanci</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1344.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The study introduces a projection-based approach called SIGFRIED to simplify kinship estimation in admixed populations. The accuracy and efficiency of the method are demonstrated using simulated and real datasets. A secure federated kinship estimation framework is proposed, along with a secure kinship estimator using homomorphic encryption-based primitives. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BRIEFINGS IN BIOINFORMATICS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/26436098/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Evolutionary Biology </span> </div> <h4> <a href="https://www.peeref.com/works/33834539" class="text-dark hover-underline">Implications of methodologies for integrating empirical kinships into ex situ population management using PMx: A case study of Baer's Pochard (Aythya baeri) in North America</a> </h4> <p class="text-ellipsis-2">Asako Y. Chaille, Robert C. Lacy, Andrea S. Putnam, Jamie L. Toste, Aryn P. Wilder, Jamie A. Ivy</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/4624.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The integration of empirical kinships into the genetic management of ex situ populations can impact genetic summary statistics and highlights the importance of understanding the scale of molecular kinships. This study focuses on Baer's pochard and provides guidance on incorporating empirical kinships into population management. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">JOURNAL OF HEREDITY</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/33834539/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/24609598" class="text-dark hover-underline">Streamlining the decision-making process for international DNA kinship matching using Worldwide allele frequencies and tailored cutoff log10LR thresholds</a> </h4> <p class="text-ellipsis-2">Francois-Xavier Laurent, Andrea Fischer, Robert F. Oldt, Sree Kanthaswamy, John S. Buckleton, Susan Hitchin</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2908.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The identification of human remains belonging to missing persons is a challenge for forensic genetics, with DNA being a valuable tool for supporting potential associations. Indirect identification through DNA from missing person's relatives is common in cases where reference DNA samples cannot be collected. While implementing DNA kinship matching nationally is feasible, challenges need to be addressed before applying this method internationally. This study introduces a method for international DNA kinship matching, aiding in the classification of potential candidates based on DNA evidence strength and reducing adventitious matches in missing person investigations. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/24609598/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Medicine, Legal </span> </div> <h4> <a href="https://www.peeref.com/works/22497672" class="text-dark hover-underline">Pairwise kinship testing with microhaplotypes: Can advancements be made in kinship inference with these markers?</a> </h4> <p class="text-ellipsis-2">Riga Wu, Hui Chen, Ran Li, Yu Zang, Xuefeng Shen, Bo Hao, Qiangwei Wang, Hongyu Sun</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2907.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The study found that 54 highly polymorphic microhaplotypes are reliable for first-degree relationship testing, but not sufficient for distant relationship testing. Therefore, more markers need to be added to improve the accuracy of kinship testing. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL</span> (2021) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/22497672/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/21292460" class="text-dark hover-underline">Distinguishing pedigree relationships via multi-way identity by descent sharing and sex-specific genetic maps</a> </h4> <p class="text-ellipsis-2">Ying Qiao, Jens G. Sannerud, Sayantani Basu-Roy, Caroline Hayward, Amy L. Williams</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/424.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The study highlights the importance of relatedness modeling and pedigree-based analyses in genetic datasets with multiple close relatives. CREST, an accurate and fast method, effectively identifies pedigree relationships among close relatives, outperforming traditional methods in classifying different types of kinship relationships. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">AMERICAN JOURNAL OF HUMAN GENETICS</span> (2021) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/21292460/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/26795527" class="text-dark hover-underline">Two-locus identity coefficients in pedigrees</a> </h4> <p class="text-ellipsis-2">Magnus Dehli Vigeland</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/8818.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This paper proposes a solution to a long-standing problem of joint distribution of allelic identity by descent between two individuals at two linked loci. The recursive algorithm described in this paper and its implementation in R allow efficient calculation of two-locus identity coefficients in any pedigree. This enables the application of existing procedures and techniques to complex and inbred relationships. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">G3-GENES GENOMES GENETICS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/26795527/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Behavioral Sciences </span> </div> <h4> <a href="https://www.peeref.com/works/27204001" class="text-dark hover-underline">Turnover in male dominance offsets the positive effect of polygyny on within-group relatedness</a> </h4> <p class="text-ellipsis-2">Mark Dyble, Tim H. Clutton-Brock</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1045.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> In species with polygynous mating systems, the high male reproductive skew and frequent changes in male dominance due to intense competition between males may not necessarily increase average genetic relatedness within groups. Previous studies have suggested an association between cooperative breeding systems and average coefficients of relatedness in vertebrates, but in multiparous polygynous animals with intense male competition, paternal relatedness and average kinship between multigenerational group members are reduced due to frequent male turnover. A theoretical model shows that increases in turnover rates of breeding males in polygynous systems can offset the positive effect of male skew on relatedness within seasons, suggesting that polygynous mating systems may not necessarily lead to significant increases in average relatedness, especially when there is extensive overlap between generations among group members. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BEHAVIORAL ECOLOGY</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/27204001/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Forestry </span> </div> <h4> <a href="https://www.peeref.com/works/23951761" class="text-dark hover-underline">Kinship Analysis and Pedigree Reconstruction of a Natural Regenerated Cork Oak (Quercus suber) Population</a> </h4> <p class="text-ellipsis-2">Bruna Mendes, Teresa Sampaio, Marta A. Antunes, Hugo Magalhaes, Filipe Costa e Silva, Carla Borges, Fernanda Simoes, Ana Usie, Maria Helena Almeida, Antonio Marcos Ramos</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/8812.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigates the potential of using SNP genotyping to predict kinship and reconstruct pedigrees in a natural cork oak population. By genotyping a total of 494 trees, the study reveals a large number of relationships among individuals, demonstrating the importance of SNP genotyping in cork oak breeding and conservation programs. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORESTS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/23951761/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemical Research Methods </span> </div> <h4> <a href="https://www.peeref.com/works/25266820" class="text-dark hover-underline">QuickPed: an online tool for drawing pedigrees and analysing relatedness</a> </h4> <p class="text-ellipsis-2">Magnus D. Vigeland</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1243.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> QuickPed is a user-friendly pedigree tool aimed at researchers, case workers, and teachers. It contains features not found in other similar tools and makes advanced relatedness analyses available for non-bioinformaticians. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BMC BIOINFORMATICS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/25266820/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 "> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/26836912" class="text-dark hover-underline">Compound and Conditioned Likelihood Ratio Behavior within a Probabilistic Genotyping Context</a> </h4> <p class="text-ellipsis-2">Kyle Duke, Daniela Cuenca, Steven Myers, Jeanette Wallin</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/9770.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> In DNA mixture analysis, comparing compound likelihood ratios and simple likelihood ratio products can help evaluate the contribution of questioned individuals to mixed DNA. The study found that the magnitude of increase in likelihood ratios depends on the proportion and input of DNA mixture. The impact of constrained genotype combinations on the outcome of likelihood ratio calculations is comparable whether the restriction is applied before or after interpretation. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">GENES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/26836912/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> </div> <div id="articles_from_authors" class="tab-pane "> <div class="nodata my-4">No Data Available</div> </div> <div id="articles_from_journal" class="tab-pane "> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83039808" class="text-dark hover-underline">Application of a newly constructed NGS panel with 45 X-linked microhaplotypes demonstrates the unique value of X-MH for kinship testing and mixture analysis</a> </h4> <p class="text-ellipsis-2">Guanju Ma, Kailiang Liu, Chaolong Lu, Qingqing Du, Mengjie Zhang, Qian Wang, Guangping Fu, Junyan Wang, Chunling Ma, Bin Cong, Shujin Li, Lihong Fu</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study screened 63 X-MHs, evaluated their performance, and calculated population parameters. The panel performed well in personal identification and paternity testing, and showed unique advantages in complex kinship and male DNA mixture analyses. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83039808/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83225861" class="text-dark hover-underline">Profiling age and body fluid DNA methylation markers using nanopore adaptive sampling</a> </h4> <p class="text-ellipsis-2">Zaka Wing-Sze Yuen, Somasundhari Shanmuganandam, Maurice Stanley, Simon Jiang, Nadine Hein, Runa Daniel, Dennis McNevin, Cameron Jack, Eduardo Eyras</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> DNA methylation plays a crucial role in physiological processes and can be used as a biomarker for body fluid identification and age prediction. Current methylation detection methods rely on various techniques and markers, requiring specialized DNA preparation and biochemical treatments. This study used nanopore adaptive sampling technology to simultaneously identify age-associated and body fluid-specific methylation markers without the need for specialized DNA preparation or biochemical treatments. The technology was consistent with whole-genome bisulfite sequencing data and identified new sites strongly correlated with age. This study lays the foundation for the development of nanopore-based methods for age prediction and body fluid identification. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83225861/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83112863" class="text-dark hover-underline">Improved individual identification in DNA mixtures of unrelated or related contributors through massively parallel sequencing</a> </h4> <p class="text-ellipsis-2">Zhiyong Liu, Enlin Wu, Ran Li, Jiajun Liu, Yu Zang, Bin Cong, Riga Wu, Bo Xie, Hongyu Sun</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study evaluated the impact of potential kinship on individual identification, including MPS performance, the influence of genetic markers on kinship and NOC inference, the probability distribution of MAC and TAC, trends in LR values, and comparisons of length- and sequence-based STR genotypes. Results showed that multiple genetic markers improved the accuracy of kinship and NOC inference, the LR value of the POI depended on the mixing ratio, and the correct kinship hypothesis yielded more conservative LR values. In addition, using sequence-based STR genotypes increased the power of individual identification and the accuracy of mixture ratio inference. The MGIEasy Signature Identification Library Prep kit demonstrated robust individual identification capabilities and is suitable for forensic DNA mixture interpretation. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83112863/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83547292" class="text-dark hover-underline">Forensic efficiency evaluation of a mtDNA whole genome sequencing system constructed with long fragment amplification strategy on DNA nanoball sequencing platform</a> </h4> <p class="text-ellipsis-2">Man Chen, Chong Chen, Ning Li, Yuerong Su, Wei Cui, Yan Huang, Meiming Cai, Bofeng Zhu</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study evaluated a novel mtDNA whole genome sequencing system using long fragment amplification strategy on the DNA nanoball sequencing platform. The system demonstrated high sequencing quality and specific mtDNA sequencing efficiencies on positive control DNA and FTA bloodstain samples. In addition, the system sequencing efficiency was also confirmed among different kinds of samples. In summary, the system showed high performance in analyzing mtDNA sequence information, and had great prospects in forensic application and maternal genetic research. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83547292/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83094956" class="text-dark hover-underline">Sequencing-induced artefacts in NGS STR data</a> </h4> <p class="text-ellipsis-2">Yao-Yuan Liu, Kevin Cheng, Rebecca Just, Sana Enke, Jo-Anne Bright</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This paper mainly introduces the high-read count noise sequences observed in the analysis of DNA profiles using the MiSeq FGx sequencing system, as well as the characteristics and causes of these noise sequences. The authors also introduce the methods used to detect these noise sequences and the help these methods provide to the laboratory. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83094956/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83110084" class="text-dark hover-underline">Shedding more light on shedders</a> </h4> <p class="text-ellipsis-2">Piyamas Petcharoen, Madison Nolan, K. Paul Kirkbride, Adrian Linacre</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study tested 100 individuals to demonstrate the reproducibility of the cell staining process in a large population. The results showed that 98 donors had consistent and reproducible cell number deposition, with no difference between the left and right thumbs, and more cells deposited by males than females. The study also suggested that shedder status may be a continuum phenomenon. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83110084/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83010213" class="text-dark hover-underline">Saliva-derived secondary DNA transfer on fabric: The impact of varying conditions</a> </h4> <p class="text-ellipsis-2">Melanie S. Gegar, German A. Cisneros, Joanne Cox, Melanie Richard, Krista A. Currie</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigated the secondary DNA transfer of saliva on different fabrics, including the effects of saliva moisture, contact methods, and other factors on DNA transfer. The study found that nylon fabric is more likely to transfer DNA than cotton and towel fabric, and wet saliva is more likely to transfer DNA than dry and rehydrated saliva. Active pressure is more likely to transfer DNA than controlled pressure. In addition, the study found that in some cases, the amount of DNA transferred to the secondary fabric is sufficient for STR-PCR amplification. These findings help us better understand the mechanism of DNA transfer and provide useful information for forensic science and criminal investigations. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83010213/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83645405" class="text-dark hover-underline">Rapid detection of blood using a novel application of RT-RPA integrated with CRISPR-Cas: ALAS2 detection as a model</a> </h4> <p class="text-ellipsis-2">Chih-Wen Su, Yi-Che Hsu, Li-Chin Tsai, James Chun- Lee, Adrian Linacre, Hsing-Mei Hsieh</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> A blood test method based on recombinase polymerase amplification, CRISPR-Cas, and lateral flow assay is reported, which is rapid, sensitive, and specific, and can detect the ALAS2 marker in blood. The test can use extracted RNA or directly added body fluids as templates, with a low detection limit, and can only detect blood, not other body fluids. When peripheral blood is mixed with saliva or semen, the test results will be affected. This method is expected to be applied in places far from the laboratory, such as crime scenes. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83645405/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/82908069" class="text-dark hover-underline">Unique molecular identifier-based amplicon sequencing of microhaplotypes for background noise mitigation</a> </h4> <p class="text-ellipsis-2">Ye-Lim Kwon, Kyoung-Jin Shin</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study designed a UMI-based amplicon sequencing system, MH-UMIseq, which can simultaneously amplify 46 MHs and generate MPS libraries in four steps. The performance of the system was evaluated using Illumina NextSeq 550 and MiniSeq systems, and the results showed that the system can significantly suppress background noise, and the proportion of unsuppressed noise decreased significantly with the increase of input DNA. Therefore, the resolution of the MH-UMIseq system is expected to be higher than that of traditional MPS. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/82908069/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83140740" class="text-dark hover-underline">A novel type of three band pattern at STR loci</a> </h4> <p class="text-ellipsis-2">B. Rolf, A. Phillip, K. Hannig, S. Koehler, I. Goettesdorfer</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> SE33 or ACTBP2 is the most polymorphic locus in many national DNA databases and commercial STR kits. This article describes the molecular reason for the three-band pattern of SE33, which is caused by the SNP in the flanking SE33 region that leads to the binding of the unlabeled D3S1358 primer, generating a chimeric PCR product smaller than the regular SE33 amplicon. This three-band pattern is called Type 3, and its genetic basis is different from Type 1 and Type 2. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83140740/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83347599" class="text-dark hover-underline">'Low' LRs obtained from DNA mixtures: On calibration and discrimination performance of probabilistic genotyping software</a> </h4> <p class="text-ellipsis-2">M. McCarthy-Allen, O. Bleka, R. Ypma, P. Gill, C. Benschop</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study evaluated the performance of various PG software in the low LR range using the PROVEDIt dataset and found that previously reported LR thresholds may be too high, suggesting that they be lowered or discarded. The study also emphasizes the importance of calibration metrics in understanding the performance of PG systems. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83347599/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83754813" class="text-dark hover-underline">Comprehensive body fluid identification and contributor assignment by combining targeted sequencing of mRNA and coding region SNPs</a> </h4> <p class="text-ellipsis-2">Maximilian Neis, Theresa Gross, Harald Schneider, Peter M. Schneider, Cornelius Courts</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This article describes the development of an mRNA/cSNP panel for forensic genetic analysis, which can provide crucial contextualizing information on the source level about a trace's composition and reduce the risk of association fallacies by typing individual coding region SNPs. The panel has high reliable detection sensitivity and low RNA input, and further optimization and improvement are needed in the future. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83754813/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83775519" class="text-dark hover-underline">A multiplex microbial profiling system for the identification of the source of body fluid and skin samples</a> </h4> <p class="text-ellipsis-2">Hewen Yao, Yanyun Wang, Shuangshuang Wang, Chaoran Sun, Yuxiang Zhou, Lanrui Jiang, Zefei Wang, Xindi Wang, Zhirui Zhang, Tingting Yang, Feng Song, Haibo Luo</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> In this study, a multiplex system with seven microbial markers was developed to distinguish between skin, saliva, and feces samples. The system accurately identified sample types by generating specific electropherograms and was further tested and classified by beta diversity analysis and skin microenvironment cluster analysis. In addition, a machine learning prediction model was established to identify the skin microenvironment with an accuracy of 79%. These findings provide new insights into the application of microbial markers in forensic science. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83775519/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/27322024" class="text-dark hover-underline">Kinship analysis of skeletal remains from the Middle Ages</a> </h4> <p class="text-ellipsis-2">Mirela Dzehverovic, Belma Jusic, Amela Pilav, Tamara Lukic, Jasmina Cakar</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> Medieval cemeteries in Travnik, Bosnia and Herzegovina were excavated from 2011 to 2014, revealing skeletal remains of 11 individuals. Genetic analysis was conducted on these remains to test familial relationships and predict Y-haplogroup. Autosomal and Y-STR markers were analyzed, and kinship analysis showed direct brother-brother relatives with a high probability. Y-STR profiles indicated the same paternal lineage and J2a haplogroup for all male individuals. This study highlights the importance of utilizing STR markers and additional markers like Y-STRs in archaeogenetic studies to obtain comprehensive information on relatives and ancestry. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/27322024/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 "> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/27322030" class="text-dark hover-underline">DNA transfer when using gloves in burglary simulations</a> </h4> <p class="text-ellipsis-2">L. Carrara, T. Hicks, L. Samie, F. Taroni, V. Castella</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> Several studies have shown that DNA can be transferred from an individual to a surface indirectly. This means that finding DNA that matches a person does not necessarily prove that they have touched the surface where the DNA was found. This research simulated cases where DNA was recovered from a door handle and compared it to reference DNA profiles, emphasizing the need to evaluate DNA results when the person of interest has a legitimate reason for their DNA to be present. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/27322030/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="modal fade" id="export-citation" tabindex="-1"> <div class="modal-dialog"> <div class="modal-content"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal"><span>×</span></button> <h4 class="modal-title">Export Citation <b class="text-primary"></b></h4> </div> <div class="modal-body"> 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