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The D1 family consists of D1- and D5-receptor subtypes and the D2 family consists of D2-, D3-, and D4-receptor subtypes. The amino acid sequences of these... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_18439505" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">There are two families of dopamine (DA) receptors, called D1 and D2, respectively. The D1 family consists of D1- and D5-receptor subtypes and the D2 family consists of D2-, D3-, and D4-receptor subtypes. The amino acid sequences of these receptors show that they all belong to a large superfamily of receptors with seven transmembrane domains, which are coupled to their</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18439505" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="350df5e294382c0e01896567aa1f07df" rel="nofollow" data-download="{"attachment_id":42169120,"asset_id":18439505,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42169120/download_file?st=MTczMjQxMjYzNiw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38447597" href="https://independent.academia.edu/JeanmarieMaloteaux">Jean-marie Maloteaux</a><script data-card-contents-for-user="38447597" type="text/json">{"id":38447597,"first_name":"Jean-marie","last_name":"Maloteaux","domain_name":"independent","page_name":"JeanmarieMaloteaux","display_name":"Jean-marie Maloteaux","profile_url":"https://independent.academia.edu/JeanmarieMaloteaux?f_ri=606","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_18439505 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18439505"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18439505, container: ".js-paper-rank-work_18439505", }); 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itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/51896199/Osteopathic_Palpation_of_the_Heart">Osteopathic Palpation of the Heart</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In the panorama of scientific literature, there is a paucity of literature on how to palpate the heart area in the osteopathic setting and relevant indications on which palpatory sensations the clinician should perceive during the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_51896199" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In the panorama of scientific literature, there is a paucity of literature on how to palpate the heart area in<br />the osteopathic setting and relevant indications on which palpatory sensations the clinician should perceive<br />during the evaluation. The article reviews the fascial anatomy of the heart area and the heart movements<br />derived from magnetic resonance imaging (MRI) studies and describes the landmarks used by the cardiac<br />surgeon to visualize the mediastinal area. The text sets out possible suggestions for a more adequate<br />osteopathic palpatory evaluation and describes any tactile sensations arising from the patient's chest. To the<br />knowledge of the authors, this is the first article that seeks to lay solid foundations for the improvement of<br />osteopathic manual medicine in the cardiology field.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51896199" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cc07c21fac7a49082f3bb4081212474c" rel="nofollow" data-download="{"attachment_id":69412287,"asset_id":51896199,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69412287/download_file?st=MTczMjQxMjYzNiw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="133898797" href="https://usf.academia.edu/AllanEscher">Allan Escher</a><script data-card-contents-for-user="133898797" type="text/json">{"id":133898797,"first_name":"Allan","last_name":"Escher","domain_name":"usf","page_name":"AllanEscher","display_name":"Allan Escher","profile_url":"https://usf.academia.edu/AllanEscher?f_ri=606","photo":"https://0.academia-photos.com/133898797/42868781/34255813/s65_allan.escher.jpg"}</script></span></span></li><li class="js-paper-rank-work_51896199 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="51896199"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 51896199, container: ".js-paper-rank-work_51896199", }); 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The article reviews the fascial anatomy of the heart area and the heart movements\nderived from magnetic resonance imaging (MRI) studies and describes the landmarks used by the cardiac\nsurgeon to visualize the mediastinal area. The text sets out possible suggestions for a more adequate\nosteopathic palpatory evaluation and describes any tactile sensations arising from the patient's chest. 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Sierkova. – Vinnytsya: Nova Knyha, 2019. – 408 p.</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Textbook in Internal medicine consists of 30 chapters. This textbook is made up of text material and enough illustrations, including clinical findings and schematic figures. The textbook is intended for English-speaking students of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_40716728" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Textbook in Internal medicine consists of 30 chapters. This textbook is made up of text material and enough illustrations, including clinical findings and schematic figures. The textbook is intended for English-speaking students of medical and pharmaceutical faculties of higher educational establishments of Ukraine. <br /> <br />Підручник з внутрішньої медицини складається з 30 розділів. Містить текстові матеріали та достатньо ілюстрацій, у тому числі клінічні матеріали та схематичні рисунки. 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data-card-contents-for-ri="46824" type="text/json">{"id":46824,"name":"Echocardiography","url":"https://www.academia.edu/Documents/in/Echocardiography?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=79351006]'), work: {"id":79351006,"title":"Frequency of Left Ventricular Thrombus in Patients With Anterior Wall Acute Myocardial Infarction Treated With Percutaneous Coronary Intervention and Dual Antiplatelet 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Kinase","url":"https://www.academia.edu/Documents/in/Creatine_Kinase?f_ri=606"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=606"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged?f_ri=606"},{"id":378016,"name":"Myocardial Infarction","url":"https://www.academia.edu/Documents/in/Myocardial_Infarction?f_ri=606"},{"id":572754,"name":"Antiplatelet Therapy","url":"https://www.academia.edu/Documents/in/Antiplatelet_Therapy?f_ri=606"},{"id":584601,"name":"Chi Square Distribution","url":"https://www.academia.edu/Documents/in/Chi_Square_Distribution?f_ri=606"},{"id":1154249,"name":"Heart Ventricles","url":"https://www.academia.edu/Documents/in/Heart_Ventricles?f_ri=606"},{"id":2463779,"name":"Combined Modality Therapy","url":"https://www.academia.edu/Documents/in/Combined_Modality_Therapy?f_ri=606"},{"id":3501173,"name":"Left Ventricular","url":"https://www.academia.edu/Documents/in/Left_Ventricular?f_ri=606"},{"id":3789879,"name":"Cardiovascular medicine and haematology","url":"https://www.academia.edu/Documents/in/Cardiovascular_medicine_and_haematology?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_73194940" data-work_id="73194940" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/73194940/Changing_Outcomes_of_Pulmonary_Artery_Banding_With_the_Percutaneously_Adjustable_Pulmonary_Artery_Band">Changing Outcomes of Pulmonary Artery Banding With the Percutaneously Adjustable Pulmonary Artery Band</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/73194940" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a44fabe223744b51110a7662d89a0960" rel="nofollow" data-download="{"attachment_id":81809289,"asset_id":73194940,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81809289/download_file?st=MTczMjQxMjYzNiw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="52505548" href="https://independent.academia.edu/shivchoudhary2">shiv choudhary</a><script data-card-contents-for-user="52505548" type="text/json">{"id":52505548,"first_name":"shiv","last_name":"choudhary","domain_name":"independent","page_name":"shivchoudhary2","display_name":"shiv choudhary","profile_url":"https://independent.academia.edu/shivchoudhary2?f_ri=606","photo":"https://0.academia-photos.com/52505548/22281430/21501020/s65_shiv.choudhary.jpg"}</script></span></span></li><li class="js-paper-rank-work_73194940 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="73194940"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 73194940, container: ".js-paper-rank-work_73194940", }); });</script></li><li class="js-percentile-work_73194940 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 73194940; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_73194940"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_73194940 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="73194940"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 73194940; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=73194940]").text(description); $(".js-view-count-work_73194940").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_73194940").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="73194940"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="606" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3429" href="https://www.academia.edu/Documents/in/Educational_Research">Educational Research</a>, <script data-card-contents-for-ri="3429" type="text/json">{"id":3429,"name":"Educational Research","url":"https://www.academia.edu/Documents/in/Educational_Research?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="10882" href="https://www.academia.edu/Documents/in/Evolution">Evolution</a>, <script data-card-contents-for-ri="10882" type="text/json">{"id":10882,"name":"Evolution","url":"https://www.academia.edu/Documents/in/Evolution?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a><script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=73194940]'), work: {"id":73194940,"title":"Changing Outcomes of Pulmonary Artery Banding With the Percutaneously Adjustable Pulmonary Artery 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Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=606"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=606"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models?f_ri=606"},{"id":2226523,"name":"Pulmonary circulation","url":"https://www.academia.edu/Documents/in/Pulmonary_circulation?f_ri=606"},{"id":2369445,"name":"Pulmonary Artery","url":"https://www.academia.edu/Documents/in/Pulmonary_Artery?f_ri=606"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=606"},{"id":3789879,"name":"Cardiovascular medicine and haematology","url":"https://www.academia.edu/Documents/in/Cardiovascular_medicine_and_haematology?f_ri=606"},{"id":4022629,"name":"minimally invasive surgical procedures","url":"https://www.academia.edu/Documents/in/minimally_invasive_surgical_procedures?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_64329457" data-work_id="64329457" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/64329457/SCCT_guidelines_for_the_interpretation_and_reporting_of_coronary_computed_tomographic_angiography">SCCT guidelines for the interpretation and reporting of coronary computed tomographic angiography</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/64329457" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="702ed7db4549291e8e61044b9e34f286" rel="nofollow" data-download="{"attachment_id":76414478,"asset_id":64329457,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/76414478/download_file?st=MTczMjQxMjYzNiw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="195410558" href="https://independent.academia.edu/JamesEarls3">James Earls</a><script data-card-contents-for-user="195410558" type="text/json">{"id":195410558,"first_name":"James","last_name":"Earls","domain_name":"independent","page_name":"JamesEarls3","display_name":"James Earls","profile_url":"https://independent.academia.edu/JamesEarls3?f_ri=606","photo":"https://0.academia-photos.com/195410558/57792886/46015456/s65_james.earls.png"}</script></span></span></li><li class="js-paper-rank-work_64329457 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="64329457"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 64329457, container: ".js-paper-rank-work_64329457", }); });</script></li><li class="js-percentile-work_64329457 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 64329457; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_64329457"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_64329457 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="64329457"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 64329457; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=64329457]").text(description); $(".js-view-count-work_64329457").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_64329457").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="64329457"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="606" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="640" href="https://www.academia.edu/Documents/in/Radiology">Radiology</a>, <script data-card-contents-for-ri="640" type="text/json">{"id":640,"name":"Radiology","url":"https://www.academia.edu/Documents/in/Radiology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1648" href="https://www.academia.edu/Documents/in/Computed_Tomography">Computed Tomography</a>, <script data-card-contents-for-ri="1648" type="text/json">{"id":1648,"name":"Computed Tomography","url":"https://www.academia.edu/Documents/in/Computed_Tomography?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="2725" href="https://www.academia.edu/Documents/in/Documentation">Documentation</a><script data-card-contents-for-ri="2725" type="text/json">{"id":2725,"name":"Documentation","url":"https://www.academia.edu/Documents/in/Documentation?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=64329457]'), work: {"id":64329457,"title":"SCCT guidelines for the interpretation and reporting of coronary computed tomographic angiography","created_at":"2021-12-15T09:22:07.036-08:00","url":"https://www.academia.edu/64329457/SCCT_guidelines_for_the_interpretation_and_reporting_of_coronary_computed_tomographic_angiography?f_ri=606","dom_id":"work_64329457","summary":null,"downloadable_attachments":[{"id":76414478,"asset_id":64329457,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":195410558,"first_name":"James","last_name":"Earls","domain_name":"independent","page_name":"JamesEarls3","display_name":"James Earls","profile_url":"https://independent.academia.edu/JamesEarls3?f_ri=606","photo":"https://0.academia-photos.com/195410558/57792886/46015456/s65_james.earls.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false},{"id":640,"name":"Radiology","url":"https://www.academia.edu/Documents/in/Radiology?f_ri=606","nofollow":false},{"id":1648,"name":"Computed Tomography","url":"https://www.academia.edu/Documents/in/Computed_Tomography?f_ri=606","nofollow":false},{"id":2725,"name":"Documentation","url":"https://www.academia.edu/Documents/in/Documentation?f_ri=606","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=606"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=606"},{"id":172678,"name":"Artifacts","url":"https://www.academia.edu/Documents/in/Artifacts?f_ri=606"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=606"},{"id":374984,"name":"Coronary Angiography","url":"https://www.academia.edu/Documents/in/Coronary_Angiography?f_ri=606"},{"id":375133,"name":"Calcinosis","url":"https://www.academia.edu/Documents/in/Calcinosis?f_ri=606"},{"id":466424,"name":"Internationality","url":"https://www.academia.edu/Documents/in/Internationality?f_ri=606"},{"id":704648,"name":"Clinical Competence","url":"https://www.academia.edu/Documents/in/Clinical_Competence?f_ri=606"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease?f_ri=606"},{"id":922266,"name":"Computed Tomographic Angiography","url":"https://www.academia.edu/Documents/in/Computed_Tomographic_Angiography?f_ri=606"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=606"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=606"},{"id":2356404,"name":"Coronary artery","url":"https://www.academia.edu/Documents/in/Coronary_artery?f_ri=606"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=606"},{"id":3009044,"name":"quality assurance in health care","url":"https://www.academia.edu/Documents/in/quality_assurance_in_health_care?f_ri=606"},{"id":3789879,"name":"Cardiovascular medicine and haematology","url":"https://www.academia.edu/Documents/in/Cardiovascular_medicine_and_haematology?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_58270819" data-work_id="58270819" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/58270819/Molecular_Diagnosis_of_Bacterial_Definite_Infective_Endocarditis_by_Real_Time_Polymerase_Chain_Reaction">Molecular Diagnosis of Bacterial Definite Infective Endocarditis by Real-Time Polymerase Chain Reaction</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Infective endocarditis (IE) can be diagnosed using the Duke criteria, which cannot be conclusive especially when the results of blood cultures are negative. This study aimed at using real-time polymerase chain reaction (PCR) technique to... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_58270819" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Infective endocarditis (IE) can be diagnosed using the Duke criteria, which cannot be conclusive especially when the results of blood cultures are negative. This study aimed at using real-time polymerase chain reaction (PCR) technique to isolate bacteria present in whole blood samples of patients with definitive IE on the basis of the method designed in this study. This laboratory and test study was conducted on 20 whole blood samples taken from patients with definitive IE. Real-time PCR of the 16s rRNA was utilized to directly analyze whole blood samples to diagnose bacterial IE. Of 20 whole blood samples with definitive IE, only one blood culture (5%) was positive and the isolated bacterium belonged to group. Also, 13 whole blood samples were positive using real-time PCR technique. The isolated bacteria were with seven (35%) cases, with two (10%) cases, with one (5%) case, with one (5%) case, with one (5%) case, and with one (5%) case. Sensitivity, specificity, positive predictive...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/58270819" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4f2ef4f8c602c8e0f6220aedd44d7af4" rel="nofollow" data-download="{"attachment_id":72764765,"asset_id":58270819,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/72764765/download_file?st=MTczMjQxMjYzNiw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32657600" href="https://independent.academia.edu/MohammadtaghiSarebanhassanabadi">Mohammadtaghi Sarebanhassanabadi</a><script data-card-contents-for-user="32657600" type="text/json">{"id":32657600,"first_name":"Mohammadtaghi","last_name":"Sarebanhassanabadi","domain_name":"independent","page_name":"MohammadtaghiSarebanhassanabadi","display_name":"Mohammadtaghi Sarebanhassanabadi","profile_url":"https://independent.academia.edu/MohammadtaghiSarebanhassanabadi?f_ri=606","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_58270819 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="58270819"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 58270819, container: ".js-paper-rank-work_58270819", }); });</script></li><li class="js-percentile-work_58270819 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 58270819; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_58270819"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_58270819 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="58270819"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 58270819; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=58270819]").text(description); $(".js-view-count-work_58270819").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_58270819").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="58270819"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i></div><span class="InlineList-item-text u-textTruncate u-pl6x"><a class="InlineList-item-text" data-has-card-for-ri="606" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a><script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (false) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=58270819]'), work: {"id":58270819,"title":"Molecular Diagnosis of Bacterial Definite Infective Endocarditis by Real-Time Polymerase Chain Reaction","created_at":"2021-10-15T21:11:15.530-07:00","url":"https://www.academia.edu/58270819/Molecular_Diagnosis_of_Bacterial_Definite_Infective_Endocarditis_by_Real_Time_Polymerase_Chain_Reaction?f_ri=606","dom_id":"work_58270819","summary":"Infective endocarditis (IE) can be diagnosed using the Duke criteria, which cannot be conclusive especially when the results of blood cultures are negative. This study aimed at using real-time polymerase chain reaction (PCR) technique to isolate bacteria present in whole blood samples of patients with definitive IE on the basis of the method designed in this study. This laboratory and test study was conducted on 20 whole blood samples taken from patients with definitive IE. Real-time PCR of the 16s rRNA was utilized to directly analyze whole blood samples to diagnose bacterial IE. Of 20 whole blood samples with definitive IE, only one blood culture (5%) was positive and the isolated bacterium belonged to group. Also, 13 whole blood samples were positive using real-time PCR technique. The isolated bacteria were with seven (35%) cases, with two (10%) cases, with one (5%) case, with one (5%) case, with one (5%) case, and with one (5%) case. Sensitivity, specificity, positive predictive...","downloadable_attachments":[{"id":72764765,"asset_id":58270819,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32657600,"first_name":"Mohammadtaghi","last_name":"Sarebanhassanabadi","domain_name":"independent","page_name":"MohammadtaghiSarebanhassanabadi","display_name":"Mohammadtaghi Sarebanhassanabadi","profile_url":"https://independent.academia.edu/MohammadtaghiSarebanhassanabadi?f_ri=606","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_57241652" data-work_id="57241652" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/57241652/Circulating_Lipid_Hydroperoxides_Predict_Cardiovascular_Events_in_Patients_With_Stable_Coronary_Artery_Disease">Circulating Lipid Hydroperoxides Predict Cardiovascular Events in Patients With Stable Coronary Artery Disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This study was designed to determine the predictive value of lipid hydroperoxide (LOOH) levels for adverse cardiovascular outcomes in patients with stable coronary artery disease (CAD). Oxidative modification of circulating lipids... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_57241652" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This study was designed to determine the predictive value of lipid hydroperoxide (LOOH) levels for adverse cardiovascular outcomes in patients with stable coronary artery disease (CAD). Oxidative modification of circulating lipids contributes to inflammation and endothelial dysfunction, which are hallmark features of atherosclerosis. A serum biomarker of oxidation is LOOH, which is a primary product of fatty acid peroxidation. Serum LOOH levels were measured and correlated with clinical events over a 3-year period in 634 patients with angiographic evidence of CAD. Baseline LOOH levels in the highest quartile were associated with hazard ratios of 3.24 (95% confidence interval [CI] 1.86 to 5.65; p = 0.0001) for nonfatal vascular events (n = 149), 1.80 (95% CI 1.13 to 2.88; p = 0.014) for major vascular procedures (n = 139), and 2.23 (95% CI 1.44 to 3.44; p = 0.0003) for all vascular events and procedures. Baseline LOOH levels correlated with serum levels of soluble intercellular adhesion molecule-1 (p = 0.001) and thiobarbituric acid reactive substances (p = 0.001) as well as the mean percent change in stenosis for large segments &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;50% stenosed (p = 0.048). A multivariate proportional hazards model, adjusted for traditional risk factors and inflammatory markers, showed an independent effect of LOOH on nonfatal vascular events, vascular procedures, and all events or procedures. Amlodipine treatment was associated with reduced cardiovascular events and changes in LOOH levels compared with placebo. Elevated LOOH levels were predictive of nonfatal vascular events and procedures in patients with stable CAD, independent of traditional risk factors and inflammatory markers.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/57241652" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="57176650" href="https://independent.academia.edu/JanBuch">Jan Buch</a><script data-card-contents-for-user="57176650" type="text/json">{"id":57176650,"first_name":"Jan","last_name":"Buch","domain_name":"independent","page_name":"JanBuch","display_name":"Jan Buch","profile_url":"https://independent.academia.edu/JanBuch?f_ri=606","photo":"https://0.academia-photos.com/57176650/25126728/23915659/s65_jan.buch.jpg"}</script></span></span></li><li class="js-paper-rank-work_57241652 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="57241652"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 57241652, container: ".js-paper-rank-work_57241652", }); });</script></li><li class="js-percentile-work_57241652 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 57241652; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_57241652"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_57241652 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="57241652"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 57241652; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=57241652]").text(description); $(".js-view-count-work_57241652").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_57241652").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="57241652"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="606" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="49685" href="https://www.academia.edu/Documents/in/CAD">CAD</a>, <script data-card-contents-for-ri="49685" type="text/json">{"id":49685,"name":"CAD","url":"https://www.academia.edu/Documents/in/CAD?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64568" href="https://www.academia.edu/Documents/in/Humans">Humans</a>, <script data-card-contents-for-ri="64568" type="text/json">{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="75847" href="https://www.academia.edu/Documents/in/HPLC">HPLC</a><script data-card-contents-for-ri="75847" type="text/json">{"id":75847,"name":"HPLC","url":"https://www.academia.edu/Documents/in/HPLC?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=57241652]'), work: {"id":57241652,"title":"Circulating Lipid Hydroperoxides Predict Cardiovascular Events in Patients With Stable Coronary Artery Disease","created_at":"2021-10-11T12:05:13.075-07:00","url":"https://www.academia.edu/57241652/Circulating_Lipid_Hydroperoxides_Predict_Cardiovascular_Events_in_Patients_With_Stable_Coronary_Artery_Disease?f_ri=606","dom_id":"work_57241652","summary":"This study was designed to determine the predictive value of lipid hydroperoxide (LOOH) levels for adverse cardiovascular outcomes in patients with stable coronary artery disease (CAD). Oxidative modification of circulating lipids contributes to inflammation and endothelial dysfunction, which are hallmark features of atherosclerosis. A serum biomarker of oxidation is LOOH, which is a primary product of fatty acid peroxidation. Serum LOOH levels were measured and correlated with clinical events over a 3-year period in 634 patients with angiographic evidence of CAD. Baseline LOOH levels in the highest quartile were associated with hazard ratios of 3.24 (95% confidence interval [CI] 1.86 to 5.65; p = 0.0001) for nonfatal vascular events (n = 149), 1.80 (95% CI 1.13 to 2.88; p = 0.014) for major vascular procedures (n = 139), and 2.23 (95% CI 1.44 to 3.44; p = 0.0003) for all vascular events and procedures. Baseline LOOH levels correlated with serum levels of soluble intercellular adhesion molecule-1 (p = 0.001) and thiobarbituric acid reactive substances (p = 0.001) as well as the mean percent change in stenosis for large segments \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;50% stenosed (p = 0.048). A multivariate proportional hazards model, adjusted for traditional risk factors and inflammatory markers, showed an independent effect of LOOH on nonfatal vascular events, vascular procedures, and all events or procedures. Amlodipine treatment was associated with reduced cardiovascular events and changes in LOOH levels compared with placebo. Elevated LOOH levels were predictive of nonfatal vascular events and procedures in patients with stable CAD, independent of traditional risk factors and inflammatory markers.","downloadable_attachments":[],"ordered_authors":[{"id":57176650,"first_name":"Jan","last_name":"Buch","domain_name":"independent","page_name":"JanBuch","display_name":"Jan Buch","profile_url":"https://independent.academia.edu/JanBuch?f_ri=606","photo":"https://0.academia-photos.com/57176650/25126728/23915659/s65_jan.buch.jpg"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false},{"id":49685,"name":"CAD","url":"https://www.academia.edu/Documents/in/CAD?f_ri=606","nofollow":false},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans?f_ri=606","nofollow":false},{"id":75847,"name":"HPLC","url":"https://www.academia.edu/Documents/in/HPLC?f_ri=606","nofollow":false},{"id":88321,"name":"Blood Pressure","url":"https://www.academia.edu/Documents/in/Blood_Pressure?f_ri=606"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=606"},{"id":176021,"name":"CVD","url":"https://www.academia.edu/Documents/in/CVD?f_ri=606"},{"id":217407,"name":"Fox","url":"https://www.academia.edu/Documents/in/Fox?f_ri=606"},{"id":233372,"name":"Lipid peroxidation","url":"https://www.academia.edu/Documents/in/Lipid_peroxidation?f_ri=606"},{"id":274826,"name":"Hydrogen Peroxide","url":"https://www.academia.edu/Documents/in/Hydrogen_Peroxide?f_ri=606"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=606"},{"id":295452,"name":"C reactive protein","url":"https://www.academia.edu/Documents/in/C_reactive_protein?f_ri=606"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=606"},{"id":398287,"name":"Liquid Chromatography","url":"https://www.academia.edu/Documents/in/Liquid_Chromatography?f_ri=606"},{"id":749302,"name":"Indexation","url":"https://www.academia.edu/Documents/in/Indexation?f_ri=606"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease?f_ri=606"},{"id":957051,"name":"HDL","url":"https://www.academia.edu/Documents/in/HDL?f_ri=606"},{"id":3245554,"name":"Cardiovascular Events","url":"https://www.academia.edu/Documents/in/Cardiovascular_Events?f_ri=606"},{"id":3789879,"name":"Cardiovascular medicine and haematology","url":"https://www.academia.edu/Documents/in/Cardiovascular_medicine_and_haematology?f_ri=606"},{"id":3819273,"name":"Lipid peroxides","url":"https://www.academia.edu/Documents/in/Lipid_peroxides?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_51606472 coauthored" data-work_id="51606472" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/51606472/Digital_filters_for_power_spectral_density_estimation_of_heart_rhythm">Digital filters for power spectral density estimation of heart rhythm</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">In this paper digital filters for a real-time estimation of the power spectral density of stationary components of a heart rhythm are considered.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51606472" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cf2a6e6ac401254a6ca79ccf95521833" rel="nofollow" data-download="{"attachment_id":69257638,"asset_id":51606472,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69257638/download_file?st=MTczMjQxMjYzNiw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="212503676" href="https://independent.academia.edu/VFalendysh">Volodymyr Falendysh</a><script data-card-contents-for-user="212503676" type="text/json">{"id":212503676,"first_name":"Volodymyr","last_name":"Falendysh","domain_name":"independent","page_name":"VFalendysh","display_name":"Volodymyr Falendysh","profile_url":"https://independent.academia.edu/VFalendysh?f_ri=606","photo":"https://0.academia-photos.com/212503676/71603170/60051116/s65_volodymyr.falendysh.jpeg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-51606472">+1</span><div class="hidden js-additional-users-51606472"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/BohdanYavorskyy">Bohdan Yavorskyy</a></span></div></div></span><script>(function(){ var 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Yavorskyy","profile_url":"https://independent.academia.edu/BohdanYavorskyy?f_ri=606","photo":"https://0.academia-photos.com/44599598/12335688/13733154/s65_bohdan.yavorskyy.jpg"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false},{"id":129388,"name":"Patient Monitoring","url":"https://www.academia.edu/Documents/in/Patient_Monitoring?f_ri=606","nofollow":false},{"id":229390,"name":"Real Time","url":"https://www.academia.edu/Documents/in/Real_Time?f_ri=606","nofollow":false},{"id":838393,"name":"Digital Filters","url":"https://www.academia.edu/Documents/in/Digital_Filters?f_ri=606","nofollow":false},{"id":1003601,"name":"Monitoring System","url":"https://www.academia.edu/Documents/in/Monitoring_System?f_ri=606"},{"id":1474473,"name":"Power spectral density","url":"https://www.academia.edu/Documents/in/Power_spectral_density?f_ri=606"},{"id":3007784,"name":"Digital 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congenital malformations. The total blood flow in the placentae... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_47288175" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Placental blood flow was measured with the aid of radioactive microspheres, in normal (N) and manifest diabetic (MD) rats, and related to fetal body growth and incidence of congenital malformations. The total blood flow in the placentae of the MD rats was decreased to about one-half of the normal flow on gestational days 20 and 22. The placentae of the MD offspring were enlarged, whereas the fetuses in this group were smaller than normal. Thus, the placental blood flow per placental weight was drastically decreased in the MD fetuses on both days 20 and 22. In contrast, the placental blood flow per fetal weight was not different in the N and MD groups on gestational day 20 whereas it was decreased in the MD offspring on gestational day 22. Placental blood flow in the malformed fetuses of the MD group did not differ significantly from that in the nonmalformed MD fetuses.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/47288175" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2c4bdfe069fb392492363bf6ad3e4956" rel="nofollow" data-download="{"attachment_id":66467991,"asset_id":47288175,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/66467991/download_file?st=MTczMjQxMjYzNiw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38379600" href="https://independent.academia.edu/ErikssonU">Ulf Eriksson</a><script data-card-contents-for-user="38379600" type="text/json">{"id":38379600,"first_name":"Ulf","last_name":"Eriksson","domain_name":"independent","page_name":"ErikssonU","display_name":"Ulf Eriksson","profile_url":"https://independent.academia.edu/ErikssonU?f_ri=606","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_47288175 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="47288175"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 47288175, container: ".js-paper-rank-work_47288175", }); 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The total blood flow in the placentae of the MD rats was decreased to about one-half of the normal flow on gestational days 20 and 22. The placentae of the MD offspring were enlarged, whereas the fetuses in this group were smaller than normal. Thus, the placental blood flow per placental weight was drastically decreased in the MD fetuses on both days 20 and 22. In contrast, the placental blood flow per fetal weight was not different in the N and MD groups on gestational day 20 whereas it was decreased in the MD offspring on gestational day 22. Placental blood flow in the malformed fetuses of the MD group did not differ significantly from that in the nonmalformed MD fetuses.","downloadable_attachments":[{"id":66467991,"asset_id":47288175,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38379600,"first_name":"Ulf","last_name":"Eriksson","domain_name":"independent","page_name":"ErikssonU","display_name":"Ulf 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Koroner Effect of Lipid Profile of Coronary Heart Disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">ABSTRAK Penyakit jantung koroner merupakan penyakit arteri koroner yang ditandai adanya endapan lipid yang terkumpul di dalam sel yang melapisi dinding suatu arteri koroner dan menyumbat aliran darah. Tujuan penelitian mengkaji pengaruh... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_77253556" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">ABSTRAK Penyakit jantung koroner merupakan penyakit arteri koroner yang ditandai adanya endapan lipid yang terkumpul di dalam sel yang melapisi dinding suatu arteri koroner dan menyumbat aliran darah. Tujuan penelitian mengkaji pengaruh Lipid Profile Terhadap Penyakit Jantung Koroner. Disain penelitian adalah survey analitik. Sampel penelitian adalah sebagian pasien di Instalasi Rawat Jalan Penyakit Dalam RSUD Nganjuk dengan jumlah 32 orang. Variabel penelitian adalah lipid profile yang terdiri dari HDL, LDL, Trigliserida. Instrumen penelitian adalah observasi dan hasil pemeriksaan laboratorium lipid profile. Analisis data menggunakan uji Fisher Exact . Hasil penelitian menunjukkan sebagian memiliki kadar HDL yang normal, lebih dari sebagian memiliki kadar LDL dan trigliserida yang tinggi. Pasien Penyakit Jantung Koroner Di Instalasi Rawat Jalan Penyakit Dalam RSUD Nganjuk didapatkan terbanyak adalah NSTEMI dan terkecil adalah Asymtomatik. Hasil uji fisher exact menunjukkan terdapa...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/77253556" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="94db3e33dead5399a132e4e13fdd6c7e" rel="nofollow" data-download="{"attachment_id":84702984,"asset_id":77253556,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/84702984/download_file?st=MTczMjQxMjYzNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="7117032" href="https://independent.academia.edu/aidanovitasari">aida novitasari</a><script data-card-contents-for-user="7117032" type="text/json">{"id":7117032,"first_name":"aida","last_name":"novitasari","domain_name":"independent","page_name":"aidanovitasari","display_name":"aida novitasari","profile_url":"https://independent.academia.edu/aidanovitasari?f_ri=606","photo":"https://0.academia-photos.com/7117032/79314950/67878564/s65_aida.novitasari.jpeg"}</script></span></span></li><li class="js-paper-rank-work_77253556 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="77253556"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 77253556, container: ".js-paper-rank-work_77253556", }); 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Tujuan penelitian mengkaji pengaruh Lipid Profile Terhadap Penyakit Jantung Koroner. Disain penelitian adalah survey analitik. Sampel penelitian adalah sebagian pasien di Instalasi Rawat Jalan Penyakit Dalam RSUD Nganjuk dengan jumlah 32 orang. Variabel penelitian adalah lipid profile yang terdiri dari HDL, LDL, Trigliserida. Instrumen penelitian adalah observasi dan hasil pemeriksaan laboratorium lipid profile. Analisis data menggunakan uji Fisher Exact . Hasil penelitian menunjukkan sebagian memiliki kadar HDL yang normal, lebih dari sebagian memiliki kadar LDL dan trigliserida yang tinggi. Pasien Penyakit Jantung Koroner Di Instalasi Rawat Jalan Penyakit Dalam RSUD Nganjuk didapatkan terbanyak adalah NSTEMI dan terkecil adalah Asymtomatik. 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N Engl J Med 2018 Aug [rejected]</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">[rejected; see additional commentary*] Comment on “Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus: ASCEND Study” N Engl J Med 2018 Aug<br />* <a href="https://www.linkedin.com/pulse/commentary-medical-zombies-work-destroy-real-promote-alex/" rel="nofollow">https://www.linkedin.com/pulse/commentary-medical-zombies-work-destroy-real-promote-alex/</a></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/37964035" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3e1b90a5e5690556b7ef056fcd8486ee" rel="nofollow" data-download="{"attachment_id":57979555,"asset_id":37964035,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/57979555/download_file?st=MTczMjQxMjYzNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="4753213" href="https://ichnfm.academia.edu/AlexVasquez">Alex Vasquez</a><script data-card-contents-for-user="4753213" type="text/json">{"id":4753213,"first_name":"Alex","last_name":"Vasquez","domain_name":"ichnfm","page_name":"AlexVasquez","display_name":"Alex Vasquez","profile_url":"https://ichnfm.academia.edu/AlexVasquez?f_ri=606","photo":"https://0.academia-photos.com/4753213/2016212/21240053/s65_alex.vasquez.png"}</script></span></span></li><li class="js-paper-rank-work_37964035 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="37964035"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 37964035, container: ".js-paper-rank-work_37964035", }); 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pulmonary disease","url":"https://www.academia.edu/Documents/in/Chronic_obstructive_pulmonary_disease?f_ri=606"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=606"},{"id":805590,"name":"Aortic Aneurysm","url":"https://www.academia.edu/Documents/in/Aortic_Aneurysm?f_ri=606"},{"id":1144172,"name":"*Physical Exertion","url":"https://www.academia.edu/Documents/in/_Physical_Exertion?f_ri=606"},{"id":1863718,"name":"The American","url":"https://www.academia.edu/Documents/in/The_American?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8215919" data-work_id="8215919" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8215919/Clinical_implication_of_adenosine_stress_cardiac_magnetic_resonance_imaging_as_potential_gatekeeper_prior_to_invasive_examination_in_patients_with_AHA_ACC_class_II_indication_for_coronary_angiography">Clinical implication of adenosine-stress cardiac magnetic resonance imaging as potential gatekeeper prior to invasive examination in patients with AHA/ACC class II indication for coronary angiography</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background Real world cardiology is faced with a low diagnostic yield of coronary angiography (CXA) in patients presenting with ACC/AHA class II CXA indication. Our aim was to analyze the clinical implication of a Cardiac MR (CMR)... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8215919" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background Real world cardiology is faced with a low diagnostic yield of coronary angiography (CXA) in patients presenting with ACC/AHA class II CXA indication. Our aim was to analyze the clinical implication of a Cardiac MR (CMR) protocol including adenosine stress perfusion in this patient population. We examined whether CMR could enhance appropriate CXA indication and thus reduce the rate of pure diagnostic CXA. In addition, we compared the relative impact of CMR exam components (perfusion, function and viability assessment) in achieving this target. Methods 176 patients were referred for CXA with class II indication. 171 underwent complete additional CMR exam in a 1.5-T whole body CMR-scanner for myocardial function, ischemia and viability prior to CXA. The routine protocol for assessment of CAD consisted of functional imaging (long and short axes), adenosine stress- and rest-perfusion in short axis orientation and “late enhancement” imaging in long and short axes. Images were analyzed by two independent and blinded investigators. Interobserver differences were resolved by a third reader. Results There was a high association between CMR results and subsequent invasive findings (chi square for CMR perfusion deficit and stenosis >70% in CXA: 113.7, p70%. Four (2.3%) patients had false negative CMR findings. In 58 patients (33.9%) no relevant coronary artery stenosis could be observed, correctly predicted by CMR in 48 cases; in 10 (5.8%) patients CMR provided false positive results. Sensitivity of CMR to detect relevant CAD (>70% luminal narrowing) was 0.96, specificity 0.83, positive predictive value 0.92 and negative predictive value 0.92. Of the CMR components, perfusion deficit was the strongest independent predictor (odds ratio 132.3, p Conclusion In a great number of patients being referred to cath lab with ACC/AHA class II indication for CXA, CMR provides a high accuracy for decision making regarding appropriateness of the invasive exam. CMR prior to CXA could substantially reduce pure diagnostic coronary angiographies in patients with intermediate probability for CAD, in our patient-cohort from approximately 34% to 6%. Further studies are warranted to identify rare false negative CMR results.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8215919" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="816c6f8a5983ebdf4561ee4f14cf7f85" rel="nofollow" data-download="{"attachment_id":48181235,"asset_id":8215919,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48181235/download_file?st=MTczMjQxMjYzNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="16155037" href="https://king-saud.academia.edu/emanali">eman ali</a><script data-card-contents-for-user="16155037" type="text/json">{"id":16155037,"first_name":"eman","last_name":"ali","domain_name":"king-saud","page_name":"emanali","display_name":"eman ali","profile_url":"https://king-saud.academia.edu/emanali?f_ri=606","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8215919 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8215919"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8215919, container: ".js-paper-rank-work_8215919", }); 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Our aim was to analyze the clinical implication of a Cardiac MR (CMR) protocol including adenosine stress perfusion in this patient population. We examined whether CMR could enhance appropriate CXA indication and thus reduce the rate of pure diagnostic CXA. In addition, we compared the relative impact of CMR exam components (perfusion, function and viability assessment) in achieving this target. Methods 176 patients were referred for CXA with class II indication. 171 underwent complete additional CMR exam in a 1.5-T whole body CMR-scanner for myocardial function, ischemia and viability prior to CXA. The routine protocol for assessment of CAD consisted of functional imaging (long and short axes), adenosine stress- and rest-perfusion in short axis orientation and “late enhancement” imaging in long and short axes. Images were analyzed by two independent and blinded investigators. Interobserver differences were resolved by a third reader. Results There was a high association between CMR results and subsequent invasive findings (chi square for CMR perfusion deficit and stenosis \u003e70% in CXA: 113.7, p70%. Four (2.3%) patients had false negative CMR findings. In 58 patients (33.9%) no relevant coronary artery stenosis could be observed, correctly predicted by CMR in 48 cases; in 10 (5.8%) patients CMR provided false positive results. Sensitivity of CMR to detect relevant CAD (\u003e70% luminal narrowing) was 0.96, specificity 0.83, positive predictive value 0.92 and negative predictive value 0.92. Of the CMR components, perfusion deficit was the strongest independent predictor (odds ratio 132.3, p Conclusion In a great number of patients being referred to cath lab with ACC/AHA class II indication for CXA, CMR provides a high accuracy for decision making regarding appropriateness of the invasive exam. CMR prior to CXA could substantially reduce pure diagnostic coronary angiographies in patients with intermediate probability for CAD, in our patient-cohort from approximately 34% to 6%. Further studies are warranted to identify rare false negative CMR results.","downloadable_attachments":[{"id":48181235,"asset_id":8215919,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":16155037,"first_name":"eman","last_name":"ali","domain_name":"king-saud","page_name":"emanali","display_name":"eman ali","profile_url":"https://king-saud.academia.edu/emanali?f_ri=606","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false},{"id":1681,"name":"Decision Making","url":"https://www.academia.edu/Documents/in/Decision_Making?f_ri=606","nofollow":false},{"id":6200,"name":"Magnetic Resonance 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safety in health care","url":"https://www.academia.edu/Documents/in/Quality_and_safety_in_health_care?f_ri=606"},{"id":993913,"name":"Termination of Pregnancy","url":"https://www.academia.edu/Documents/in/Termination_of_Pregnancy?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_6507412" data-work_id="6507412" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/6507412/Electrical_Failure_of_an_ICD_Lead_due_to_a_Presumed_Insulation_Defect_Only_Diagnosed_by_a_Maximum_Output_Shock">Electrical Failure of an ICD Lead due to a Presumed Insulation Defect Only Diagnosed by a Maximum Output Shock</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item 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type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (false) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=6507412]'), work: {"id":6507412,"title":"Electrical Failure of an ICD Lead due to a Presumed Insulation Defect Only Diagnosed by a Maximum Output Shock","created_at":"2014-03-22T10:27:45.026-07:00","url":"https://www.academia.edu/6507412/Electrical_Failure_of_an_ICD_Lead_due_to_a_Presumed_Insulation_Defect_Only_Diagnosed_by_a_Maximum_Output_Shock?f_ri=606","dom_id":"work_6507412","summary":null,"downloadable_attachments":[{"id":33284556,"asset_id":6507412,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":10378540,"first_name":"Marwan","last_name":"Badri","domain_name":"mainlinehealth","page_name":"MarwanBadri","display_name":"Marwan Badri","profile_url":"https://mainlinehealth.academia.edu/MarwanBadri?f_ri=606","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_76977573 coauthored" data-work_id="76977573" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/76977573/COST_EFFECTIVENESS_OF_SACUBITRIL_VALSARTAN_COMPARED_TO_ANGIOTENSIN_CONVERTING_ENZYME_INHIBITORS_IN_PATIENTS_WITH_HEART_FAILURE_WITH_REDUCED_EJECTION_FRACTION">COST-EFFECTIVENESS OF SACUBITRIL–VALSARTAN COMPARED TO ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objectives: The goal of this study was to compare cost-effectiveness of sacubitril/valsartan with angiotensin-converting enzyme (ACE) inhibitors for treating chronic heart failure patients with reduced ejection fraction (HFrEF) from the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_76977573" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objectives: The goal of this study was to compare cost-effectiveness of sacubitril/valsartan with angiotensin-converting enzyme (ACE) inhibitors for treating chronic heart failure patients with reduced ejection fraction (HFrEF) from the published articles and explore the methodology applied in the studies.<br />Methods: Systematic research was conducted in February 2021 using PubMed, Cochrane, and EBSCO. A combination of MeSH terms of ‘cost-effectiveness analysis’, ‘heart failure with reduced ejection fraction’, ‘sacubitril valsartan’ and ‘angiotensin converting enzyme inhibitor’ was employed. The review selected for articles published in the last five years in English. <br />Results: A total of 15 studies were included in this review. We found that the studies had been conducted in 12 different countries. The United States had the greatest number of publications (5), followed by the Netherlands (2). The study method most used was the Markov decision model (73%). Almost all studies produced ICERs and QALYs that were numerically high.<br />Conclusions: The use of sacubitril/valsartan associates with longer life expectancy and incremental cost-effectiveness ratio than angiotensin-converting enzyme inhibitors.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/76977573" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9e15319cf93b4f6a2c913414c07709cd" rel="nofollow" data-download="{"attachment_id":84519138,"asset_id":76977573,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/84519138/download_file?st=MTczMjQxMjYzNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="98064718" href="https://uns-id.academia.edu/StefanusErdanaPutra">Stefanus Erdana Putra</a><script data-card-contents-for-user="98064718" type="text/json">{"id":98064718,"first_name":"Stefanus Erdana","last_name":"Putra","domain_name":"uns-id","page_name":"StefanusErdanaPutra","display_name":"Stefanus Erdana Putra","profile_url":"https://uns-id.academia.edu/StefanusErdanaPutra?f_ri=606","photo":"https://0.academia-photos.com/98064718/21848360/35507648/s65_stefanus_erdana.putra.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-76977573">+1</span><div class="hidden js-additional-users-76977573"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/RatihPuspitaFebrinasari">Ratih Puspita Febrinasari</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-76977573'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-76977573').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_76977573 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="76977573"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 76977573; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=76977573]").text(description); $(".js-view-count-work_76977573").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_76977573").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="76977573"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="606" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3286" href="https://www.academia.edu/Documents/in/Patient_Safety">Patient Safety</a>, <script data-card-contents-for-ri="3286" type="text/json">{"id":3286,"name":"Patient Safety","url":"https://www.academia.edu/Documents/in/Patient_Safety?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16288" href="https://www.academia.edu/Documents/in/Public_Health">Public Health</a>, <script data-card-contents-for-ri="16288" type="text/json">{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="24735" href="https://www.academia.edu/Documents/in/Cardiovascular_disease">Cardiovascular disease</a><script data-card-contents-for-ri="24735" type="text/json">{"id":24735,"name":"Cardiovascular disease","url":"https://www.academia.edu/Documents/in/Cardiovascular_disease?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=76977573]'), work: {"id":76977573,"title":"COST-EFFECTIVENESS OF SACUBITRIL–VALSARTAN COMPARED TO ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION","created_at":"2022-04-19T10:19:19.811-07:00","url":"https://www.academia.edu/76977573/COST_EFFECTIVENESS_OF_SACUBITRIL_VALSARTAN_COMPARED_TO_ANGIOTENSIN_CONVERTING_ENZYME_INHIBITORS_IN_PATIENTS_WITH_HEART_FAILURE_WITH_REDUCED_EJECTION_FRACTION?f_ri=606","dom_id":"work_76977573","summary":"Objectives: The goal of this study was to compare cost-effectiveness of sacubitril/valsartan with angiotensin-converting enzyme (ACE) inhibitors for treating chronic heart failure patients with reduced ejection fraction (HFrEF) from the published articles and explore the methodology applied in the studies.\nMethods: Systematic research was conducted in February 2021 using PubMed, Cochrane, and EBSCO. A combination of MeSH terms of ‘cost-effectiveness analysis’, ‘heart failure with reduced ejection fraction’, ‘sacubitril valsartan’ and ‘angiotensin converting enzyme inhibitor’ was employed. The review selected for articles published in the last five years in English. \nResults: A total of 15 studies were included in this review. We found that the studies had been conducted in 12 different countries. The United States had the greatest number of publications (5), followed by the Netherlands (2). The study method most used was the Markov decision model (73%). Almost all studies produced ICERs and QALYs that were numerically high.\nConclusions: The use of sacubitril/valsartan associates with longer life expectancy and incremental cost-effectiveness ratio than angiotensin-converting enzyme inhibitors.\n","downloadable_attachments":[{"id":84519138,"asset_id":76977573,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":98064718,"first_name":"Stefanus Erdana","last_name":"Putra","domain_name":"uns-id","page_name":"StefanusErdanaPutra","display_name":"Stefanus Erdana Putra","profile_url":"https://uns-id.academia.edu/StefanusErdanaPutra?f_ri=606","photo":"https://0.academia-photos.com/98064718/21848360/35507648/s65_stefanus_erdana.putra.jpg"},{"id":222098217,"first_name":"Ratih","last_name":"Puspita Febrinasari","domain_name":"independent","page_name":"RatihPuspitaFebrinasari","display_name":"Ratih Puspita Febrinasari","profile_url":"https://independent.academia.edu/RatihPuspitaFebrinasari?f_ri=606","photo":"https://0.academia-photos.com/222098217/79777096/68346852/s65_ratih.puspita_febrinasari.jpeg"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false},{"id":3286,"name":"Patient Safety","url":"https://www.academia.edu/Documents/in/Patient_Safety?f_ri=606","nofollow":false},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=606","nofollow":false},{"id":24735,"name":"Cardiovascular disease","url":"https://www.academia.edu/Documents/in/Cardiovascular_disease?f_ri=606","nofollow":false},{"id":32355,"name":"Cost Management","url":"https://www.academia.edu/Documents/in/Cost_Management?f_ri=606"},{"id":49633,"name":"Heart Failure","url":"https://www.academia.edu/Documents/in/Heart_Failure?f_ri=606"},{"id":705104,"name":"Valsartan","url":"https://www.academia.edu/Documents/in/Valsartan?f_ri=606"},{"id":719604,"name":"Angiotensin Converting Enzyme","url":"https://www.academia.edu/Documents/in/Angiotensin_Converting_Enzyme?f_ri=606"},{"id":3767164,"name":"Sacubitril","url":"https://www.academia.edu/Documents/in/Sacubitril?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17970784" data-work_id="17970784" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17970784/Core_Components_of_Cardiac_Rehabilitation_Secondary_Prevention_Programs_A_Statement_for_Healthcare_Professionals_From_the_American_Heart_Association_and_the_American_Association_of_Cardiovascular_and_Pulmonary_Rehabilitation_Writing_Group">Core Components of Cardiac Rehabilitation/Secondary Prevention Programs : A Statement for Healthcare Professionals From the American Heart Association and the American Association of Cardiovascular and Pulmonary Rehabilitation Writing Group</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Page 1. ISSN: 1524-4539 Copyright © 2000 American Heart Association. All rights reserved. Print ISSN: 0009-7322. 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Fibrillation","url":"https://www.academia.edu/Documents/in/Atrial_Fibrillation?f_ri=606"},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=606"},{"id":192110,"name":"Ontario","url":"https://www.academia.edu/Documents/in/Ontario?f_ri=606"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=606"},{"id":389152,"name":"Current","url":"https://www.academia.edu/Documents/in/Current?f_ri=606"},{"id":1317824,"name":"Amiodarone","url":"https://www.academia.edu/Documents/in/Amiodarone?f_ri=606"},{"id":2201015,"name":"Postoperative care","url":"https://www.academia.edu/Documents/in/Postoperative_care?f_ri=606"},{"id":2463621,"name":"Postoperative Complications","url":"https://www.academia.edu/Documents/in/Postoperative_Complications?f_ri=606"},{"id":2735826,"name":"Health Care Surveys","url":"https://www.academia.edu/Documents/in/Health_Care_Surveys?f_ri=606"},{"id":3194761,"name":"Quality of health care","url":"https://www.academia.edu/Documents/in/Quality_of_health_care?f_ri=606"},{"id":3539064,"name":"Adrenal cortex hormones","url":"https://www.academia.edu/Documents/in/Adrenal_cortex_hormones?f_ri=606"},{"id":3789879,"name":"Cardiovascular medicine and haematology","url":"https://www.academia.edu/Documents/in/Cardiovascular_medicine_and_haematology?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_72147540" data-work_id="72147540" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/72147540/An%C3%A1lisis_del_nivel_de_ansiedad_en_el_paciente_adulto_con_cardiopat%C3%ADa_cong%C3%A9nita_en_una_instituci%C3%B3n_de_alta_especialidad">Análisis del nivel de ansiedad en el paciente adulto con cardiopatía congénita en una institución de alta especialidad</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Introducción: Gracias a los adelantos científico-tecnológicos, cada vez son más las personas con algún tipo de cardiopatía congénita que alcanzan la edad adulta, sin embargo, esta condición supone un impacto significativo en la esfera... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72147540" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Introducción: Gracias a los adelantos científico-tecnológicos, cada vez son más las personas con algún tipo de cardiopatía congénita que alcanzan la edad adulta, sin embargo, esta condición supone un impacto significativo en la esfera emocional; por ello, en el presente estudio se hace referencia a la ansiedad. Objetivo: Analizar el nivel de ansiedad que presentan los pacientes adultos con cardiopatía congénita en una institución de alta especialidad. Material y métodos: Estudio no experimental, analítico, prospectivo y transversal. Se aplicó previo consentimiento informado, un instrumento validado sobre ansiedad State and Trait Anxiety Inventory. Se determinó una muestra estadística aleatorizada simple (n = 248) con personas mayores de 17 años que tuvieran cardiopatía congénita cianógena o acianógena. Se analizaron los datos sociodemográficos con frecuencias, porcentajes y medidas de tendencia central; se compararon y asociaron variables ordinales con U de Mann Whitney, Pearson y S...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72147540" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="16d8d2bf0fcf18a3e8bd77a48927f928" rel="nofollow" data-download="{"attachment_id":81193346,"asset_id":72147540,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81193346/download_file?st=MTczMjQxMjYzNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="157447618" href="https://independent.academia.edu/ErikaAlfaro12">Erika Alfaro</a><script data-card-contents-for-user="157447618" type="text/json">{"id":157447618,"first_name":"Erika","last_name":"Alfaro","domain_name":"independent","page_name":"ErikaAlfaro12","display_name":"Erika Alfaro","profile_url":"https://independent.academia.edu/ErikaAlfaro12?f_ri=606","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_72147540 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72147540"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72147540, container: ".js-paper-rank-work_72147540", }); 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$(".js-view-count[data-work-id=72147540]").text(description); $(".js-view-count-work_72147540").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_72147540").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="72147540"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">5</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="606" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="24735" href="https://www.academia.edu/Documents/in/Cardiovascular_disease">Cardiovascular disease</a>, <script data-card-contents-for-ri="24735" type="text/json">{"id":24735,"name":"Cardiovascular disease","url":"https://www.academia.edu/Documents/in/Cardiovascular_disease?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="101403" href="https://www.academia.edu/Documents/in/Cardiovascular_nursing">Cardiovascular nursing</a>, <script data-card-contents-for-ri="101403" type="text/json">{"id":101403,"name":"Cardiovascular nursing","url":"https://www.academia.edu/Documents/in/Cardiovascular_nursing?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="115261" href="https://www.academia.edu/Documents/in/Enfermeria">Enfermeria</a><script data-card-contents-for-ri="115261" type="text/json">{"id":115261,"name":"Enfermeria","url":"https://www.academia.edu/Documents/in/Enfermeria?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72147540]'), work: {"id":72147540,"title":"Análisis del nivel de ansiedad en el paciente adulto con cardiopatía congénita en una institución de alta especialidad","created_at":"2022-02-21T16:31:04.322-08:00","url":"https://www.academia.edu/72147540/An%C3%A1lisis_del_nivel_de_ansiedad_en_el_paciente_adulto_con_cardiopat%C3%ADa_cong%C3%A9nita_en_una_instituci%C3%B3n_de_alta_especialidad?f_ri=606","dom_id":"work_72147540","summary":"Introducción: Gracias a los adelantos científico-tecnológicos, cada vez son más las personas con algún tipo de cardiopatía congénita que alcanzan la edad adulta, sin embargo, esta condición supone un impacto significativo en la esfera emocional; por ello, en el presente estudio se hace referencia a la ansiedad. Objetivo: Analizar el nivel de ansiedad que presentan los pacientes adultos con cardiopatía congénita en una institución de alta especialidad. Material y métodos: Estudio no experimental, analítico, prospectivo y transversal. Se aplicó previo consentimiento informado, un instrumento validado sobre ansiedad State and Trait Anxiety Inventory. Se determinó una muestra estadística aleatorizada simple (n = 248) con personas mayores de 17 años que tuvieran cardiopatía congénita cianógena o acianógena. Se analizaron los datos sociodemográficos con frecuencias, porcentajes y medidas de tendencia central; se compararon y asociaron variables ordinales con U de Mann Whitney, Pearson y S...","downloadable_attachments":[{"id":81193346,"asset_id":72147540,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":157447618,"first_name":"Erika","last_name":"Alfaro","domain_name":"independent","page_name":"ErikaAlfaro12","display_name":"Erika Alfaro","profile_url":"https://independent.academia.edu/ErikaAlfaro12?f_ri=606","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false},{"id":24735,"name":"Cardiovascular disease","url":"https://www.academia.edu/Documents/in/Cardiovascular_disease?f_ri=606","nofollow":false},{"id":101403,"name":"Cardiovascular nursing","url":"https://www.academia.edu/Documents/in/Cardiovascular_nursing?f_ri=606","nofollow":false},{"id":115261,"name":"Enfermeria","url":"https://www.academia.edu/Documents/in/Enfermeria?f_ri=606","nofollow":false},{"id":675863,"name":"Ansiedad","url":"https://www.academia.edu/Documents/in/Ansiedad?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_72007465" data-work_id="72007465" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/72007465/Parental_Concerns_Based_General_Developmental_Screening_Tool_and_Autism_Risk_The_Taiwan_National_Birth_Cohort_Study">Parental Concerns Based General Developmental Screening Tool and Autism Risk: The Taiwan National Birth Cohort Study</a></div></div><div class="u-pb4x 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data-has-card-for-ri="154" href="https://www.academia.edu/Documents/in/Endocrinology">Endocrinology</a>, <script data-card-contents-for-ri="154" type="text/json">{"id":154,"name":"Endocrinology","url":"https://www.academia.edu/Documents/in/Endocrinology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="156" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a>, <script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="606" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1085" href="https://www.academia.edu/Documents/in/Epidemiology">Epidemiology</a><script data-card-contents-for-ri="1085" type="text/json">{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology?f_ri=606","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72007465]'), work: {"id":72007465,"title":"Parental Concerns Based General Developmental Screening Tool and Autism Risk: The Taiwan National Birth Cohort Study","created_at":"2022-02-20T14:22:52.509-08:00","url":"https://www.academia.edu/72007465/Parental_Concerns_Based_General_Developmental_Screening_Tool_and_Autism_Risk_The_Taiwan_National_Birth_Cohort_Study?f_ri=606","dom_id":"work_72007465","summary":null,"downloadable_attachments":[{"id":81113363,"asset_id":72007465,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36632110,"first_name":"For-wey","last_name":"Lung","domain_name":"independent","page_name":"ForweyLung","display_name":"For-wey Lung","profile_url":"https://independent.academia.edu/ForweyLung?f_ri=606","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":154,"name":"Endocrinology","url":"https://www.academia.edu/Documents/in/Endocrinology?f_ri=606","nofollow":false},{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=606","nofollow":false},{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=606","nofollow":false},{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology?f_ri=606","nofollow":false},{"id":2249,"name":"Autism","url":"https://www.academia.edu/Documents/in/Autism?f_ri=606"},{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=606"},{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=606"},{"id":62896,"name":"Allergy","url":"https://www.academia.edu/Documents/in/Allergy?f_ri=606"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female?f_ri=606"},{"id":118523,"name":"Checklist","url":"https://www.academia.edu/Documents/in/Checklist?f_ri=606"},{"id":131185,"name":"Cohort Study","url":"https://www.academia.edu/Documents/in/Cohort_Study?f_ri=606"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult?f_ri=606"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=606"},{"id":561987,"name":"Asian Continental Ancestry Group","url":"https://www.academia.edu/Documents/in/Asian_Continental_Ancestry_Group?f_ri=606"},{"id":770944,"name":"Fetus","url":"https://www.academia.edu/Documents/in/Fetus?f_ri=606"},{"id":942031,"name":"Birth Cohort","url":"https://www.academia.edu/Documents/in/Birth_Cohort?f_ri=606"},{"id":1217494,"name":"Early Diagnosis","url":"https://www.academia.edu/Documents/in/Early_Diagnosis?f_ri=606"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=606"},{"id":2489699,"name":"Autistic disorder","url":"https://www.academia.edu/Documents/in/Autistic_disorder?f_ri=606"},{"id":2533306,"name":"cultural characteristics","url":"https://www.academia.edu/Documents/in/cultural_characteristics?f_ri=606"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_71172982" data-work_id="71172982" itemscope="itemscope" 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class="InlineList-item"><div class="download"><a id="c734bbd0e6e66b64a07cc8f0dd5520b9" rel="nofollow" data-download="{"attachment_id":80635063,"asset_id":71172982,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80635063/download_file?st=MTczMjQxMjYzNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="2157074" href="https://marionegri.academia.edu/eugeniosantoro">eugenio santoro</a><script data-card-contents-for-user="2157074" type="text/json">{"id":2157074,"first_name":"eugenio","last_name":"santoro","domain_name":"marionegri","page_name":"eugeniosantoro","display_name":"eugenio santoro","profile_url":"https://marionegri.academia.edu/eugeniosantoro?f_ri=606","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_71172982 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="71172982"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 71172982, container: ".js-paper-rank-work_71172982", }); });</script></li><li class="js-percentile-work_71172982 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" 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