Cell Biology

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Cells are the basic units of life, and understanding them is crucial for all biological sciences. This field encompasses a wide range of topics, including the physiological properties, metabolic processes, signaling pathways, life cycle, and interactions of cells with their environment.</div><div><a href="https://cellbiology.blog/knowledgebase/why-is-cell-biology-important" title="Why is Cell Biology Important?"><h3>Why is Cell Biology Important?</h3></a>Cell Biology is fundamental to understanding the complexities of all living organisms. It provides insights into how organisms grow, develop, and function at the most basic level. Advances in cell biology have led to breakthroughs in medical research, including the development of new treatments for diseases, understanding genetic disorders, and the creation of vaccines.</div><div><a href="https://cellbiology.blog/knowledgebase/what-are-the-main-components-of-a-cell" title="What are the Main Components of a Cell?"><h3>What are the Main Components of a Cell?</h3></a>Cells are composed of various <a href="https://cellbiology.blog/about/index/organelles" title="organelles" target="_blank">organelles</a> that perform specific functions. These include the <a href="https://cellbiology.blog/about/index/nucleus" title="nucleus" target="_blank">nucleus</a>, which houses genetic material; the <a href="https://cellbiology.blog/about/index/mitochondria" title="mitochondria" target="_blank">mitochondria</a>, known as the powerhouses of the cell; the <a href="https://cellbiology.blog/about/index/endoplasmic-reticulum" title="endoplasmic reticulum" target="_blank">endoplasmic reticulum</a>, involved in protein and lipid synthesis; and the <a href="https://cellbiology.blog/about/index/golgi-apparatus" title="Golgi apparatus" target="_blank">Golgi apparatus</a>, which modifies, sorts, and packages proteins for secretion. Other essential components include the <a href="https://cellbiology.blog/about/index/cell-membrane" title="cell membrane" target="_blank">cell membrane</a>, <a href="https://cellbiology.blog/about/index/cytoskeleton" title="cytoskeleton" target="_blank">cytoskeleton</a>, and <a href="https://cellbiology.blog/about/index/ribosomes" title="ribosomes" target="_blank">ribosomes</a>.</div><div><a href="https://cellbiology.blog/knowledgebase/how-do-cells-communicate" title="How Do Cells Communicate?"><h3>How Do Cells Communicate?</h3></a>Cells communicate through <a href="https://cellbiology.blog/about/index/cell-signaling" title="cell signaling" target="_blank">cell signaling</a>, which involves the transmission of chemical signals between cells. This communication is crucial for coordinating various functions in multicellular organisms, such as growth, immune responses, and homeostasis. Cells use <a href="https://cellbiology.blog/about/index/receptors" title="receptors" target="_blank">receptors</a> on their surfaces to detect signaling molecules like <a href="https://cellbiology.blog/about/index/hormones" title="hormones" target="_blank">hormones</a>, <a href="https://cellbiology.blog/about/index/neurotransmitters" title="neurotransmitters" target="_blank">neurotransmitters</a>, and <a href="https://cellbiology.blog/about/index/cytokines" title="cytokines" target="_blank">cytokines</a>.</div><div><a href="https://cellbiology.blog/knowledgebase/what-is-cell-division-and-why-is-it-important" title="What is Cell Division and Why is it Important?"><h3>What is Cell Division and Why is it Important?</h3></a><a href="https://cellbiology.blog/about/index/cell-division" title="Cell division" target="_blank">Cell division</a> is the process by which a parent cell divides into two or more daughter cells. This process is essential for growth, development, and tissue repair in multicellular organisms. There are two main types of cell division: <a href="https://cellbiology.blog/about/index/mitosis" title="mitosis" target="_blank">mitosis</a> and <a href="https://cellbiology.blog/about/index/meiosis" title="meiosis" target="_blank">meiosis</a>. Mitosis results in two genetically identical daughter cells, while meiosis leads to the production of gametes (sperm and eggs) with half the genetic material of the parent cell.</div><div><a href="https://cellbiology.blog/knowledgebase/how-do-cells-obtain-energy" title="How Do Cells Obtain Energy?"><h3>How Do Cells Obtain Energy?</h3></a>Cells obtain energy through <a href="https://cellbiology.blog/about/index/metabolism" title="metabolism" target="_blank">metabolism</a>, which includes all the chemical reactions that occur within a cell. The primary source of energy for cells is <a href="https://cellbiology.blog/about/index/adenosine-triphosphate-(atp)" title="adenosine triphosphate (ATP)" target="_blank">adenosine triphosphate (ATP)</a>. Cells generate ATP through processes like <a href="https://cellbiology.blog/about/index/glycolysis" title="glycolysis" target="_blank">glycolysis</a>, the <a href="https://cellbiology.blog/about/index/citric-acid-cycle-(krebs-cycle)" title="citric acid cycle (Krebs cycle)" target="_blank">citric acid cycle (Krebs cycle)</a>, and <a href="https://cellbiology.blog/about/index/oxidative-phosphorylation" title="oxidative phosphorylation" target="_blank">oxidative phosphorylation</a>. <a href="https://cellbiology.blog/about/index/photosynthetic" title="Photosynthetic" target="_blank">Photosynthetic</a> cells, such as plant cells, can also produce energy through <a href="https://cellbiology.blog/about/index/photosynthesis" title="photosynthesis" target="_blank">photosynthesis</a>.</div><div><a href="https://cellbiology.blog/knowledgebase/what-techniques-are-used-in-cell-biology" title="What Techniques are Used in Cell Biology?"><h3>What Techniques are Used in Cell Biology?</h3></a>Various <a href="https://cellbiology.blog/about/index/techniques" title="techniques" target="_blank">techniques</a> are employed in cell biology to study cells. These include <a href="https://cellbiology.blog/about/index/microscopy" title="microscopy" target="_blank">microscopy</a>, which allows scientists to visualize cells and their structures; <a href="https://cellbiology.blog/about/index/cell-culture" title="cell culture" target="_blank">cell culture</a>, which involves growing cells in controlled conditions; <a href="https://cellbiology.blog/about/index/molecular-cloning" title="molecular cloning" target="_blank">molecular cloning</a>, which enables the study of genes and proteins; and <a href="https://cellbiology.blog/about/index/flow-cytometry" title="flow cytometry" target="_blank">flow cytometry</a>, which is used to analyze the physical and chemical characteristics of cells.</div><div><a href="https://cellbiology.blog/knowledgebase/what-are-stem-cells" title="What are Stem Cells?"><h3>What are Stem Cells?</h3></a><a href="https://cellbiology.blog/about/index/stem-cells" title="Stem cells" target="_blank">Stem cells</a> are undifferentiated cells with the ability to develop into different cell types. They play a crucial role in development, growth, and tissue repair. There are two main types of stem cells: <a href="https://cellbiology.blog/about/index/embryonic-stem-cells" title="embryonic stem cells" target="_blank">embryonic stem cells</a>, which can differentiate into any cell type, and <a href="https://cellbiology.blog/about/index/adult-stem-cells" title="adult stem cells" target="_blank">adult stem cells</a>, which are limited to differentiating into cell types of their tissue of origin. The potential of stem cells in regenerative medicine and therapeutic applications is a significant area of research in cell biology.</div><div><a href="https://cellbiology.blog/knowledgebase/what-are-some-common-cell-biology-disorders" title="What are Some Common Cell Biology Disorders?"><h3>What are Some Common Cell Biology Disorders?</h3></a>Various <a href="https://cellbiology.blog/about/index/disorders" title="disorders" target="_blank">disorders</a> arise from abnormalities in cell function and division. These include <a href="https://cellbiology.blog/about/index/cancer" title="cancer" target="_blank">cancer</a>, which is characterized by uncontrolled cell division; <a href="https://cellbiology.blog/about/index/genetic-disorders" title="genetic disorders" target="_blank">genetic disorders</a> like <a href="https://cellbiology.blog/about/index/cystic-fibrosis" title="cystic fibrosis" target="_blank">cystic fibrosis</a> and <a href="https://cellbiology.blog/about/index/down-syndrome" title="Down syndrome" target="_blank">Down syndrome</a>; and <a href="https://cellbiology.blog/about/index/neurodegenerative-diseases" title="neurodegenerative diseases" target="_blank">neurodegenerative diseases</a> such as <a href="https://cellbiology.blog/about/index/alzheimer's-disease" title="Alzheimer's disease" target="_blank">Alzheimer's disease</a> and <a href="https://cellbiology.blog/about/index/parkinson's-disease" title="Parkinson's disease" target="_blank">Parkinson's disease</a>. Understanding the cellular mechanisms underlying these disorders is essential for developing effective treatments.</div><div><h3>Future Directions in Cell Biology</h3>The future of cell biology holds tremendous potential with advancements in technologies such as <a href="https://cellbiology.blog/about/index/crispr-cas9" title="CRISPR-Cas9" target="_blank">CRISPR-Cas9</a> gene editing, <a href="https://cellbiology.blog/about/index/single-cell-sequencing" title="single-cell sequencing" target="_blank">single-cell sequencing</a>, and <a href="https://cellbiology.blog/about/index/organ-on-a-chip" title="organ-on-a-chip" target="_blank">organ-on-a-chip</a> models. These innovations will enhance our understanding of cellular processes and lead to new therapeutic strategies for treating diseases.</div></div> </div> <div id="recent_papers"> <br><hr /><br><h2 class="heading1">Relevant Publications</h2> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947080" target='_blank' title="Transferrin receptor-based circulating tumor cell enrichment provides a snapshot of the molecular landscape of solid tumors and correlates with clinical outcomes.">Transferrin receptor-based circulating tumor cell enrichment provides a snapshot of the molecular landscape of solid tumors and correlates with clinical outcomes.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947524" target='_blank' title="Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi.">Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38948051" target='_blank' title="Influence of deep eutectic solvents on redox biocatalysis involving alcohol dehydrogenases.">Influence of deep eutectic solvents on redox biocatalysis involving alcohol dehydrogenases.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947230" target='_blank' title="Clinical and Genomic Profile of Primary Cranial Neurolymphomatosis.">Clinical and Genomic Profile of Primary Cranial Neurolymphomatosis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div 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Dynamics in Resistance to EGFR Inhibitors for NSCLC.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945477" target='_blank' title="Whole mount immunofluorescence analysis of fresh and stored human donor corneas highlights changes in limbal characteristics during storage.">Whole mount immunofluorescence analysis of fresh and stored human donor corneas highlights changes in limbal characteristics during storage.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947401" target='_blank' title="Exosomes in Bone Cancer: Unveiling their Vital Role in Diagnosis, Prognosis, and Therapeutic Advancements.">Exosomes in Bone Cancer: Unveiling their Vital Role in Diagnosis, Prognosis, and Therapeutic Advancements.</a> 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haematobium and Schistosoma bovis first generation hybrids undergo gene expressions changes consistent with species compatibility and heterosis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38954046" target='_blank' title="GSDME-mediated pyroptosis promotes anti-tumor immunity of neoadjuvant chemotherapy in breast cancer.">GSDME-mediated pyroptosis promotes anti-tumor immunity of neoadjuvant chemotherapy in breast cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38951662" target='_blank' title="Enhancing in situ cancer vaccines using delivery technologies.">Enhancing in situ cancer vaccines using delivery technologies.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38951909" target='_blank' title="A prospective study of HER3 expression pre and post neoadjuvant therapy of different breast cancer subtypes: implications for HER3 imaging therapy guidance.">A prospective study of HER3 expression pre and post neoadjuvant therapy of different breast cancer subtypes: implications for HER3 imaging therapy guidance.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38943021" target='_blank' title="Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue.">Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div 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mesenchymal stem cell exosomes alleviate necrotizing enterocolitis in neonatal mice by regulating intestinal epithelial cells autophagy.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38949349" target='_blank' title="Poissonian Cellular Potts Models Reveal Nonequilibrium Kinetics of Cell Sorting.">Poissonian Cellular Potts Models Reveal Nonequilibrium Kinetics of Cell Sorting.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38767365" target='_blank' title="Isolation of Nuclei from Human Intermuscular Adipose Tissue and Downstream Single-Nuclei RNA Sequencing.">Isolation of Nuclei from Human Intermuscular Adipose Tissue and Downstream Single-Nuclei RNA Sequencing.</a> </div> <p><strong>Issue Release:</strong> 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